Summary: Blood pressure levels that are between normotension and hypertension. Individuals with prehypertension are at a higher risk for developing cardiovascular diseases. Generally, prehypertension is defined as SYSTOLIC PRESSURE of 131-139 mm Hg and/or DIASTOLIC PRESSURE of 81-89 when the optimal is 120/80 mm Hg. For diabetics and other metabolism diseases the prehypertension is around 110-129/70-79 mm Hg.

Top Publications

  1. Schiffrin E. Inflammation, immunity and development of essential hypertension. J Hypertens. 2014;32:228-9 pubmed publisher
  2. Gorelick P. Blood pressure and the prevention of cognitive impairment. JAMA Neurol. 2014;71:1211-3 pubmed publisher
  3. Mendy V, Perryman B, Hawkins J, Dove C. Planning for the strategic recruitment of barbershops for blood pressure screening and referral in the Mississippi Delta region. Prev Chronic Dis. 2014;11:E126 pubmed publisher
  4. Falkner B. Prehypertension in adolescents: how high is the risk for hypertension?. J Pediatr. 2012;160:7-9 pubmed publisher
  5. Kissel C, Anderson T. Role of endothelin-1 and endothelial dysfunction in prehypertension. Can J Cardiol. 2012;28:251-3 pubmed publisher
  6. Madias J. Sustained blood pressure lowering effect of twice daily remote ischemic conditioning sessions in a normotensive/prehypertensive subject. Int J Cardiol. 2015;182:392-4 pubmed publisher
  7. Bano N. Prehypertension among young adult females in Dammam, Saudi Arabia. East Mediterr Health J. 2013;19:899-900 pubmed
  8. Lin S, Lee K, Lin K, Cheng K, Tsai W, Sheu S, et al. Prevalence of prehypertension and associated risk factors in a rural Taiwanese adult population. Int J Cardiol. 2010;144:269-73 pubmed publisher
    ..on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure has recently introduced the prehypertension category of blood pressure status that needs monitoring and intervention...
  9. Pengpid S, Peltzer K, Ferrer A. Prehypertension and associated factors among university students in the Philippines. Int J Adolesc Med Health. 2014;26:245-52 pubmed publisher
    b>Prehypertension is a new category of blood pressure, and is considered a cardiovascular risk factor. The aim of this study was to estimate the prevalence of prehypertension and its associated factors in young adults in the Philippines...

More Information


  1. Li W, Jin C, Vaidya A, Wu Y, Rexrode K, Zheng X, et al. Blood Pressure Trajectories and the Risk of Intracerebral Hemorrhage and Cerebral Infarction: A Prospective Study. Hypertension. 2017;70:508-514 pubmed publisher
    ..trajectories was labeled according to their BP range and pattern over time: normotensive-stable (n=26 740), prehypertension-stable (n=35 674), stage 1 hypertension-increasing (n=8215), stage 1 hypertension-decreasing (n=6422), and ..
  2. Plat J, Severins N, Morrison S, Mensink R. Effects of NWT-03, an egg-protein hydrolysate, on blood pressure in normotensive, high-normotensive and mild-hypertensive men and women: a dose-finding study. Br J Nutr. 2017;117:942-950 pubmed publisher
    ..As no dose-response relationship was evident, these results should be interpreted with care, and additional studies are needed. ..
  3. Madias J, Koulouridis I. Effect of repeat twice daily sessions of remote ischemic conditioning over the course of one week on blood pressure of a normotensive/prehypertensive subject. Int J Cardiol. 2014;176:1076-7 pubmed publisher
  4. Mazor Aronovitch K, Lotan D, Modan Moses D, Fradkin A, Pinhas Hamiel O. Blood pressure in obese and overweight children and adolescents. Isr Med Assoc J. 2014;16:157-61 pubmed
    ..Hypertension was documented in 17.2% of the study group at the second measurement. Elevated BP was diagnosed in 31% of overweight and obese children and adolescents. Increased awareness and early diagnosis and treatment are essential. ..
  5. Alessi A, Brandão A, Paiva A, Rocha Nogueira A, Feitosa A, Campos Gonzaga C, et al. I Brazilian position paper on prehypertension, white coat hypertension and masked hypertension: diagnosis and management. Arq Bras Cardiol. 2014;102:110-8 pubmed
  6. Guo X, Zhang X, Guo L, Li Z, Zheng L, Yu S, et al. Association between pre-hypertension and cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Curr Hypertens Rep. 2013;15:703-16 pubmed
    The quantitative associations between prehypertension or its separate blood pressure (BP) ranges and the risk of main cardiovascular diseases (CVDs) have not been reliably documented...
  7. Huang Y, Cai X, Liu C, Zhu D, Hua J, Hu Y, et al. Prehypertension and the risk of coronary heart disease in Asian and Western populations: a meta-analysis. J Am Heart Assoc. 2015;4: pubmed publisher
    The results of studies on the association between prehypertension (blood pressure 120 to 139/80 to 89 mm Hg) and coronary heart disease (CHD) remain controversial...
  8. Pannarale G, Moroni C, Acconcia M, Pannitteri G, Truscelli G, Valente L, et al. The natural history of prehypertension. A 20-year follow-up. Eur Rev Med Pharmacol Sci. 2017;21:1329-1334 pubmed
    According to the JNC7 report, prehypertension category includes subjects with systolic blood pressure between 120 and 139 mmHg and/or diastolic blood pressure between 80 and 89 mmHg that would be at risk for developing hypertension and ..
  9. Fukushima K, Morokuma S, Tsukimori K, Murata M, Wake N. Blood pressure measurements within the JNC7 pre-hypertensive range after 32 weeks of gestation are a risk factor for decreased fetal growth. Hypertens Res. 2012;35:128-30 pubmed publisher
  10. Booth J, Li J, Zhang L, Chen L, Muntner P, Egan B. Trends in Prehypertension and Hypertension Risk Factors in US Adults: 1999-2012. Hypertension. 2017;70:275-284 pubmed publisher
    b>Prehypertension is associated with increased risk for hypertension and cardiovascular disease...
  11. Adams S, DeLorey D, Davenport M, Stickland M, Fairey A, North S, et al. Effects of high-intensity aerobic interval training on cardiovascular disease risk in testicular cancer survivors: A phase 2 randomized controlled trial. Cancer. 2017;123:4057-4065 pubmed publisher
    ..Further research concerning the long-term effects of HIIT on CVD morbidity and mortality in TCS is warranted. Cancer 2017;123:4057-65. © 2017 American Cancer Society. ..
  12. Rossi G. Does primary aldosteronism exist in normotensive and mildly hypertensive patients, and should we look for it?. Hypertens Res. 2011;34:43-6 pubmed publisher