coronary artery disease

Summary

Summary: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.

Top Publications

  1. . Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661-78 pubmed
    ..identified 24 independent association signals at P < 5 x 10(-7): 1 in bipolar disorder, 1 in coronary artery disease, 9 in Crohn's disease, 3 in rheumatoid arthritis, 7 in type 1 diabetes and 3 in type 2 diabetes...
  2. Ding E, Smit L, Hu F. The metabolic syndrome as a cluster of risk factors: is the whole greater than the sum of its parts?: comment on "The metabolic syndrome, its component risk factors, and progression of coronary atherosclerosis". Arch Intern Med. 2010;170:484-5 pubmed publisher
  3. Ehret G, Munroe P, Rice K, Bochud M, Johnson A, Chasman D, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011;478:103-9 pubmed publisher
    ..significant variants was associated with hypertension, left ventricular wall thickness, stroke and coronary artery disease, but not kidney disease or kidney function...
  4. Gundapaneni K, Shyamala N, Galimudi R, Kupsal K, Gantala S, Padala C, et al. Polymorphic variants of Caspase genes (8 & 3) in the risk prediction of Coronary Artery Disease. Gene. 2017;627:278-283 pubmed publisher
    Apoptosis has been involved in a number of pathological conditions including coronary artery disease (CAD). Caspases (CASP) are important regulators and executioners in both extrinsic and intrinsic apoptotic pathways...
  5. Phie J, Krishna S, Moxon J, Omer S, Kinobe R, Golledge J. Flavonols reduce aortic atherosclerosis lesion area in apolipoprotein E deficient mice: A systematic review and meta-analysis. PLoS ONE. 2017;12:e0181832 pubmed publisher
    ..Based on the included studies, the flavonols appear to be the most effective flavonoids for reducing aortic atherosclerotic lesion area in apolipoprotein E deficient mice. ..
  6. Gaudino M, Antoniades C, Benedetto U, Deb S, Di Franco A, Di Giammarco G, et al. Mechanisms, Consequences, and Prevention of Coronary Graft Failure. Circulation. 2017;136:1749-1764 pubmed publisher
    ..Intraoperative flow verification and secondary prevention using antiplatelet and lipid-lowering agents can help reducing the incidence of graft failure. ..
  7. Lytvyn Y, Bjornstad P, Udell J, Lovshin J, Cherney D. Sodium Glucose Cotransporter-2 Inhibition in Heart Failure: Potential Mechanisms, Clinical Applications, and Summary of Clinical Trials. Circulation. 2017;136:1643-1658 pubmed publisher
    ..use of SGLT2 inhibition in patients without T2D with HF or at risk of HF, such as in patients with coronary artery disease or hypertension...
  8. Petretta M, Cuocolo A. Screening asymptomatic patients with type 2 diabetes is recommended: Pro. J Nucl Cardiol. 2015;22:1225-8 pubmed publisher
  9. Fujiyoshi A, Jacobs D, Fitzpatrick A, Alonso A, Duprez D, Sharrett A, et al. Coronary Artery Calcium and Risk of Dementia in MESA (Multi-Ethnic Study of Atherosclerosis). Circ Cardiovasc Imaging. 2017;10: pubmed publisher
    ..This is consistent with a hypothesis that vascular injuries play a role in the development of dementia. ..
  10. Favarato D, Gutierrez P. Case 5/2016 - A 56-Year-old Man Hospitalized for Unstable Angina, who Presented Recurrence of Precordial Pain and Cardiac Arrest with Pulseless Electrical Activity. Arq Bras Cardiol. 2016;107:485-490 pubmed publisher

Detail Information

Publications62

  1. . Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661-78 pubmed
    ..identified 24 independent association signals at P < 5 x 10(-7): 1 in bipolar disorder, 1 in coronary artery disease, 9 in Crohn's disease, 3 in rheumatoid arthritis, 7 in type 1 diabetes and 3 in type 2 diabetes...
  2. Ding E, Smit L, Hu F. The metabolic syndrome as a cluster of risk factors: is the whole greater than the sum of its parts?: comment on "The metabolic syndrome, its component risk factors, and progression of coronary atherosclerosis". Arch Intern Med. 2010;170:484-5 pubmed publisher
  3. Ehret G, Munroe P, Rice K, Bochud M, Johnson A, Chasman D, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011;478:103-9 pubmed publisher
    ..significant variants was associated with hypertension, left ventricular wall thickness, stroke and coronary artery disease, but not kidney disease or kidney function...
  4. Gundapaneni K, Shyamala N, Galimudi R, Kupsal K, Gantala S, Padala C, et al. Polymorphic variants of Caspase genes (8 & 3) in the risk prediction of Coronary Artery Disease. Gene. 2017;627:278-283 pubmed publisher
    Apoptosis has been involved in a number of pathological conditions including coronary artery disease (CAD). Caspases (CASP) are important regulators and executioners in both extrinsic and intrinsic apoptotic pathways...
  5. Phie J, Krishna S, Moxon J, Omer S, Kinobe R, Golledge J. Flavonols reduce aortic atherosclerosis lesion area in apolipoprotein E deficient mice: A systematic review and meta-analysis. PLoS ONE. 2017;12:e0181832 pubmed publisher
    ..Based on the included studies, the flavonols appear to be the most effective flavonoids for reducing aortic atherosclerotic lesion area in apolipoprotein E deficient mice. ..
  6. Gaudino M, Antoniades C, Benedetto U, Deb S, Di Franco A, Di Giammarco G, et al. Mechanisms, Consequences, and Prevention of Coronary Graft Failure. Circulation. 2017;136:1749-1764 pubmed publisher
    ..Intraoperative flow verification and secondary prevention using antiplatelet and lipid-lowering agents can help reducing the incidence of graft failure. ..
  7. Lytvyn Y, Bjornstad P, Udell J, Lovshin J, Cherney D. Sodium Glucose Cotransporter-2 Inhibition in Heart Failure: Potential Mechanisms, Clinical Applications, and Summary of Clinical Trials. Circulation. 2017;136:1643-1658 pubmed publisher
    ..use of SGLT2 inhibition in patients without T2D with HF or at risk of HF, such as in patients with coronary artery disease or hypertension...
  8. Petretta M, Cuocolo A. Screening asymptomatic patients with type 2 diabetes is recommended: Pro. J Nucl Cardiol. 2015;22:1225-8 pubmed publisher
  9. Fujiyoshi A, Jacobs D, Fitzpatrick A, Alonso A, Duprez D, Sharrett A, et al. Coronary Artery Calcium and Risk of Dementia in MESA (Multi-Ethnic Study of Atherosclerosis). Circ Cardiovasc Imaging. 2017;10: pubmed publisher
    ..This is consistent with a hypothesis that vascular injuries play a role in the development of dementia. ..
  10. Favarato D, Gutierrez P. Case 5/2016 - A 56-Year-old Man Hospitalized for Unstable Angina, who Presented Recurrence of Precordial Pain and Cardiac Arrest with Pulseless Electrical Activity. Arq Bras Cardiol. 2016;107:485-490 pubmed publisher
  11. Russ M, Wackerl C, Zeymer U, Hochadel M, Kerber S, Zahn R, et al. Gender based differences in drug eluting stent implantation - data from the German ALKK registry suggest underuse of DES in elderly women. BMC Cardiovasc Disord. 2017;17:68 pubmed publisher
    Observational studies suggest there are gender based differences in the treatment of coronary artery disease, with women receiving evidence based therapy less frequently than suggested by current guidelines...
  12. Barbu M, Lindström U, Nordborg C, Martinsson A, Dworeck C, Jeppsson A. Sclerosing Aortic and Coronary Arteritis Due to IgG4-Related Disease. Ann Thorac Surg. 2017;103:e487-e489 pubmed publisher
    ..the case of a 55-year-old woman admitted for a coronary artery bypass operation because of three-vessel coronary artery disease based on angiographic findings and clinical symptoms...
  13. Nakanishi R, Baskaran L, Gransar H, Budoff M, Achenbach S, Al Mallah M, et al. Relationship of Hypertension to Coronary Atherosclerosis and Cardiac Events in Patients With Coronary Computed Tomographic Angiography. Hypertension. 2017;70:293-299 pubmed publisher
    ..64-detector row coronary computed tomographic angiography, we identified 14?803 patients without known coronary artery disease. Of these, 1434 hypertensive patients were matched to 1434 patients without hypertension...
  14. Li S, Zhang F, Cui Y, Wu M, Lee C, Song J, et al. Modified high-throughput quantification of plasma microRNAs in heparinized patients with coronary artery disease using heparinase. Biochem Biophys Res Commun. 2017;493:556-561 pubmed publisher
    ..In conclusion, we present a simple method for the removal of heparin with heparinase I, and for the subsequent successful miRNAs TLDA or RT-qPCR amplification. ..
  15. Han Q, Wu L, Li T, Meng X, Yao H. There is a link between carotid intima media thickness and coronary artery disease: It might be inflammation. Int J Cardiol. 2016;203:1144-5 pubmed publisher
  16. Christiansen M, Larsen S, Nyegaard M, Neergaard Petersen S, Ajjan R, Würtz M, et al. Coronary artery disease-associated genetic variants and biomarkers of inflammation. PLoS ONE. 2017;12:e0180365 pubmed publisher
    Genetic constitution and inflammation both contribute to development of coronary artery disease (CAD). Several CAD-associated single-nucleotide polymorphisms (SNPs) have recently been identified, but their functions are largely unknown...
  17. Ji H, Li Y, Fan Z, Zuo B, Jian X, Li L, et al. Monocyte/lymphocyte ratio predicts the severity of coronary artery disease: a syntax score assessment. BMC Cardiovasc Disord. 2017;17:90 pubmed publisher
    ..monocyte to lymphocyte ratio (MLR) provides predictive value of the lesion severity in patients with coronary artery disease (CAD)...
  18. Gumanova N, Klimushina M, Gavrilova N, Metelskaya V. [Combined markers of initial stages of coronary atherosclerosis]. Biomed Khim. 2017;63:272-277 pubmed publisher
    ..Prediktornye svo?stva dannogo testa pokazali éffektivnost' na fone primeniaemo? lekarstvenno? terapii. ..
  19. Wu M, Huang M, Chiang J, Sun M, Lee Y, Yen H. Acupuncture decreased the risk of coronary heart disease in patients with fibromyalgia in Taiwan: a nationwide matched cohort study. Arthritis Res Ther. 2017;19:37 pubmed publisher
    ..Our study confirmed that acupuncture reduced the risk of CHD in patients with fibromyalgia in Taiwan. Further clinical and mechanistic studies are warranted. ..
  20. Nicolini F, Vezzani A, Romano G, Carino D, Ricci M, Chicco M, et al. Coronary Artery Bypass Grafting with Arterial Conduits in the Elderly. Int Heart J. 2017;58:647-653 pubmed publisher
  21. Loo G, Koo C, Zhang J, Li R, Sethi R, Ong T, et al. Impact of obstructive sleep apnea on cardiovascular outcomes in patients treated with percutaneous coronary intervention: rationale and design of the sleep and stent study. Clin Cardiol. 2014;37:261-9 pubmed
    ..Based on the complete preliminary results of the first 785 recruited patients, the prevalence of OSA was 48.3%. We expect the follow-up for primary endpoint to be completed in late 2015; study results will be presented in 2016. ..
  22. Carpeggiani C, Picano E, Brambilla M, Michelassi C, Knuuti J, Kauffman P, et al. Variability of radiation doses of cardiac diagnostic imaging tests: the RADIO-EVINCI study (RADIationdOse subproject of the EVINCI study). BMC Cardiovasc Disord. 2017;17:63 pubmed publisher
    Patients with coronary artery disease can accumulate significant radiation dose through repeated exposures to coronary computed tomographic angiography, myocardial perfusion imaging with single photon emission computed tomography or ..
  23. Koolhaas C, Dhana K, Golubic R, Schoufour J, Hofman A, van Rooij F, et al. Physical Activity Types and Coronary Heart Disease Risk in Middle-Aged and Elderly Persons: The Rotterdam Study. Am J Epidemiol. 2016;183:729-38 pubmed publisher
    ..In conclusion, in this long-term follow-up study of older adults, domestic work and cycling were associated with reduced CHD risk. Physical activity should be promoted in this population with the aim to prevent CHD. ..
  24. Watanabe R, Shirai T, Namkoong H, Zhang H, Berry G, Wallis B, et al. Pyruvate controls the checkpoint inhibitor PD-L1 and suppresses T cell immunity. J Clin Invest. 2017;127:2725-2738 pubmed publisher
    Patients with coronary artery disease (CAD) are at high risk for reactivation of the varicella zoster virus (VZV) and development of herpes zoster (HZ)...
  25. Papini G, Bonomi A, Stut W, Kraal J, Kemps H, Sartor F. Proof of concept of a 45-second cardiorespiratory fitness self-test for coronary artery disease patients based on accelerometry. PLoS ONE. 2017;12:e0183740 pubmed publisher
    ..Thirty healthy subjects (40% females, 31.3 ± 7.8 yrs, 25.1 ± 3.2 BMI) and eighteen male coronary artery disease (CAD) (56.6 ± 7.4 yrs, 28.7 ± 4...
  26. Campo G, Vieceli Dalla Sega F, Pavasini R, Aquila G, Gallo F, Fortini F, et al. Biological effects of ticagrelor over clopidogrel in patients with stable coronary artery disease and chronic obstructive pulmonary disease. Thromb Haemost. 2017;117:1208-1216 pubmed publisher
    ..test if ticagrelor is superior to clopidogrel in improving endothelial function in patients with stable coronary artery disease (SCAD) and concomitant chronic obstructive pulmonary disease (COPD)...
  27. Seo M, Lee J, Hahn J, Ryu G, Hong S, Dhong H, et al. Association of Obstructive Sleep Apnea With Subclinical Cardiovascular Disease Predicted by Coronary Artery Calcium Score in Asymptomatic Subjects. Am J Cardiol. 2017;120:577-581 pubmed publisher
    ..In conclusion, the patients with intermittent hypoxemia during sleep should be considered for evaluation of coronary artery calcification to detect cardiovascular disease in subclinical status. ..
  28. Albert B, Lee A, McLendon T, Devereaux R, Odum C, Foulkes G. Is Total Elbow Arthroplasty Safe as an Outpatient Procedure?. J Surg Orthop Adv. 2017;26:25-28 pubmed
    ..Bivariate comparison showed increased prevalence of coronary artery disease in the OP group (32% vs. 7%) and increased age in the IP group (68 years vs. 58 years)...
  29. Lee S, Lin F, Lu Y, Chang H, Min J. Rationale and design of the Coronary Computed Tomographic Angiography for Selective Cardiac Catheterization: Relation to Cardiovascular Outcomes, Cost Effectiveness and Quality of Life (CONSERVE) trial. Am Heart J. 2017;186:48-55 pubmed publisher
    ..vs "direct catheterization" strategies for stable patients with suspected but without known coronary artery disease, who meet AHA/ACC guideline indication for ICA...
  30. Yamamoto M, Yamashita K, Matsumura M, Fujino A, Ishida M, Ebara S, et al. Serial 3-Vessel Optical Coherence Tomography and Intravascular Ultrasound Analysis of Changing Morphologies Associated With Lesion Progression in Patients With Stable Angina Pectoris. Circ Cardiovasc Imaging. 2017;10: pubmed publisher
    ..6; 95% confidence interval, 3.7-50.6; P<0.001). Lesion progression was categorized to distinct OCT morphologies that were related to changes in plaque mass or vessel remodeling. ..
  31. Hamilton Craig C, Chow C, Younger J, Jelinek V, Chan J, Liew G. Cardiac Society of Australia and New Zealand position statement executive summary: coronary artery calcium scoring. Med J Aust. 2017;207:357-361 pubmed
    ..High risk patients are treated with a high efficacy statin and aspirin. Very low risk patients (ie, CAC score of zero) do not benefit from treatment...
  32. Cerit L. The Tip of The Iceberg: Non-Calcified Coronary Plague and Epicardial Adipose Tissue. Arq Bras Cardiol. 2017;108:383-385 pubmed publisher
  33. Chang T, Tsai W, Huang T, Su S, Chang C, Ma H, et al. Dysregulation of endothelial colony-forming cell function by a negative feedback loop of circulating miR-146a and -146b in cardiovascular disease patients. PLoS ONE. 2017;12:e0181562 pubmed publisher
    ..a specific cell lineage of endothelial progenitor cells (EPCs) is highly associated with the severity of coronary artery disease (CAD), the most common type of cardiovascular disease (CVD)...
  34. Schmidt B, Frölich S, Dragano N, Frank M, Eisele L, Pechlivanis S, et al. Socioeconomic Status Interacts with the Genetic Effect of a Chromosome 9p21.3 Common Variant to Influence Coronary Artery Calcification and Incident Coronary Events in the Heinz Nixdorf Recall Study (Risk Factors, Evaluation of Coronary Calcium, and . Circ Cardiovasc Genet. 2017;10: pubmed publisher
    Genetic variants of a locus within the chromosome 9p21.3 region are consistently associated with coronary artery disease and coronary artery calcification (CAC). The aim of this study was to examine whether a 9p21...
  35. Marçula M, Aiello V. Case 5/2015 - 88-Year-Old Female with Chronic Coronary Artery Disease, Upper Limb Thrombosis, Atrial Fibrillation and Cardiac Arrest. Arq Bras Cardiol. 2015;105:527-35 pubmed publisher
  36. Laitinen T, Puolakka E, Ruohonen S, Magnussen C, Smith K, Viikari J, et al. Association of Socioeconomic Status in Childhood With Left Ventricular Structure and Diastolic Function in Adulthood: The Cardiovascular Risk in Young Finns Study. JAMA Pediatr. 2017;171:781-787 pubmed publisher
    ..Increased left ventricular (LV) mass and diastolic dysfunction are associated with cardiovascular disease. Prospective data on effects of childhood socioeconomic status (SES) on measures of LV structure and function are lacking...
  37. Dewey F, Gusarova V, Dunbar R, O Dushlaine C, Schurmann C, Gottesman O, et al. Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease. N Engl J Med. 2017;377:211-221 pubmed publisher
    ..We performed tests of association for loss-of-function variants in ANGPTL3 with lipid levels and with coronary artery disease in 13,102 case patients and 40,430 controls from the DiscovEHR study, with follow-up studies involving 23,..
  38. Al Asoom L. Coronary angiogenic effect of long-term administration of Nigella sativa. BMC Complement Altern Med. 2017;17:308 pubmed publisher
    ..NS effect on coronary angiogenesis needs to be explored further as it might lead to a new promising preventive and therapeutic agent of the ischemic heart disease. ..
  39. Yan Y, Song D, Liu L, Meng X, Qi C, Wang J. The relationship of plasma decoy receptor 3 and coronary collateral circulation in patients with coronary artery disease. Life Sci. 2017;189:84-88 pubmed publisher
    ..was associated with CCC formation and evaluate its predictive power for CCC status in patients with coronary artery disease. Among patients who underwent coronary angiography with coronary artery disease and had a stenosis of ?90%..
  40. Lemesle G, Tricot O, Meurice T, Lallemant R, Delomez M, Equine O, et al. Incident Myocardial Infarction and Very Late Stent Thrombosis in Outpatients With Stable Coronary Artery Disease. J Am Coll Cardiol. 2017;69:2149-2156 pubmed publisher
    ..correlates, and prognosis associated with incident myocardial infarction (MI) in patients with stable coronary artery disease (CAD)...
  41. Garg A, Rao S, Agrawal S, Theodoropoulos K, Mennuni M, Sharma A, et al. Meta-Analysis of Randomized Controlled Trials of Percutaneous Coronary Intervention With Drug-Eluting Stents Versus Coronary Artery Bypass Grafting in Left Main Coronary Artery Disease. Am J Cardiol. 2017;119:1942-1948 pubmed publisher
    ..stents (DES) compared with coronary artery bypass grafting (CABG) in selected patients with left main coronary artery disease (LMCAD)...
  42. Yamamoto Y, Iino K, Ueda H, No H, Nishida Y, Takago S, et al. Coronary Artery Bypass Grafting in a Patient With Polyarteritis Nodosa. Ann Thorac Surg. 2017;103:e431-e433 pubmed publisher
    ..Coronary angiography revealed 3-vessel coronary artery disease. We performed 2-vessel coronary artery bypass grafting with the saphenous vein because the left internal ..
  43. Zhang X, Zhu Q, Yang J, Chen Y, Li Y, Zhu S, et al. Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis. BMC Med. 2017;15:84 pubmed publisher
    The optimal revascularization technique in patients with left main coronary artery disease (CAD) remains controversial...
  44. Souza R, Alves C, de Oliveira C, Reis A, Carvalho A. Circulating levels of adiponectin and extent of coronary artery disease in patients undergoing elective coronary angiography. Braz J Med Biol Res. 2017;51:e6738 pubmed publisher
    ..and anti-atherogenic properties, is encoded by a gene whose polymorphisms are associated with presence of coronary artery disease (CAD). Serum APN levels are inversely related with presence and complexity of CAD...
  45. Smits P, Assaf A, Richardt G, Omerovic E, Abdel Wahab M, Neumann F. Design and rationale of the COMPARE-ACUTE trial: Fractional flow reserve-guided primary multivessel percutaneous coronary intervention to improve guideline indexed actual standard of care for treatment of ST-elevation myocardial infarction in patient. Am Heart J. 2017;186:21-28 pubmed publisher
    ..The aim of the COMPARE-ACUTE trial is to assess whether FFR-guided complete revascularization in the acute setting is superior to culprit lesion treatment-only therapy. ..
  46. Oksman E, Linna M, Hörhammer I, Lammintakanen J, Talja M. Cost-effectiveness analysis for a tele-based health coaching program for chronic disease in primary care. BMC Health Serv Res. 2017;17:138 pubmed publisher
    ..analysis of a tele-based health-coaching intervention among patients with type 2 diabetes (T2D), coronary artery disease (CAD) and congestive heart failure (CHF)...
  47. Leng W, Zeng X, Kwong J, Hua X. Periodontal disease and risk of coronary heart disease: An updated meta-analysis of prospective cohort studies. Int J Cardiol. 2015;201:469-72 pubmed publisher
  48. DeFilippis A, Young R, Carrubba C, McEvoy J, Budoff M, Blumenthal R, et al. An analysis of calibration and discrimination among multiple cardiovascular risk scores in a modern multiethnic cohort. Ann Intern Med. 2015;162:266-75 pubmed publisher
    ..If validated, overestimation of ASCVD risk may have substantial implications for individual patients and the health care system. National Heart, Lung, and Blood Institute. ..
  49. Salerno M, Sharif B, Arheden H, Kumar A, Axel L, Li D, et al. Recent Advances in Cardiovascular Magnetic Resonance: Techniques and Applications. Circ Cardiovasc Imaging. 2017;10: pubmed publisher
    ..in the evaluation of congenital heart disease, heart failure, cardiac masses, pericardial disease, and coronary artery disease. This review will highlight some recent novel cardiovascular magnetic resonance imaging techniques, ..
  50. Min Y, Song B, Kim H, Kim K, Lee H, Min B, et al. Associations between reflux esophagitis and the progression of coronary artery calcification: A cohort study. PLoS ONE. 2017;12:e0184996 pubmed publisher
    ..Reflux esophagitis (RE) and coronary heart disease (CHD) have common risk factors, including obesity and metabolic syndrome. This study aimed to evaluate the associations between RE and the future CHD risk...