aortitis

Summary

Summary: Inflammation of the wall of the AORTA.

Top Publications

  1. Mohamed H, Elliott B, Brothers T, Robison J. Suprarenal Clostridium septicum aortitis with rupture and simultaneous colon cancer. Ann Vasc Surg. 2006;20:825-9 pubmed
    We report a case of combined colon cancer and Clostridium septicum aortitis involving the suprarenal abdominal aorta with rupture. An 82-year-old male presented with fever, abdominal pain, and back pain associated with constipation...
  2. Adachi O, Saiki Y, Akasaka J, Oda K, Iguchi A, Tabayashi K. Surgical management of aortic regurgitation associated with takayasu arteritis and other forms of aortitis. Ann Thorac Surg. 2007;84:1950-3 pubmed
    Surgical management of aortic regurgitation associated with aortitis can be complicated with occurrence of prosthetic valve detachment or formation of pseudoaneurysm at the suture line...
  3. Gornik H, Creager M. Aortitis. Circulation. 2008;117:3039-51 pubmed publisher
  4. Selim A, Fulford L, Mohiaddin R, Sheppard M. Active aortitis in relapsing polychondritis. J Clin Pathol. 2001;54:890-2 pubmed
    ..b>Aortitis is a very rare complication...
  5. Matsuki T, Isoda K, Horai R, Nakajima A, Aizawa Y, Suzuki K, et al. Involvement of tumor necrosis factor-alpha in the development of T cell-dependent aortitis in interleukin-1 receptor antagonist-deficient mice. Circulation. 2005;112:1323-31 pubmed
    ..These mice also frequently develop aortitis at the root of the aorta, but the mechanism underlying the development of this disease has not been completely ..
  6. Siddiquee Z, Zane N, Smith R, Stone J. Dense IgG4 plasma cell infiltrates associated with chronic infectious aortitis: implications for the diagnosis of IgG4-related disease. Cardiovasc Pathol. 2012;21:470-5 pubmed publisher
    IgG4-related aortitis is a newly recognized form of noninfectious aortitis that occurs as part of the spectrum of a systemic disease referred to as IgG4-related disease...
  7. Liang K, Chowdhary V, Michet C, Miller D, Sundt T, Connolly H, et al. Noninfectious ascending aortitis: a case series of 64 patients. J Rheumatol. 2009;36:2290-7 pubmed publisher
    To identify the clinical presentation and histopathologic characteristics of noninfectious ascending aortitis. A retrospective medical record and histopathology review was performed of patients with histologic evidence of active ..
  8. Liechti M, Schob O, Kacl G, Caduff B. Clostridium septicum aortitis in a patient with colon carcinoma. Eur J Clin Microbiol Infect Dis. 2003;22:632-4 pubmed
  9. Balink H, Spoorenberg A, Houtman P, Brandenburg A, Verberne H. Early recognition of aortitis of the aorta ascendens with ¹?F-FDG PET/CT: syphilitic?. Clin Rheumatol. 2013;32:705-9 pubmed publisher
    ..on this case and existing literature on this subject, we come to the conclusion that (18)F-FDG PET/CT can help in an early establishment of syphilitic aortitis before the possible life-threatening sequelae of syphilitic aortitis occur.

More Information

Publications62

  1. Lopes R, Almeida J, Dias P, Pinho P, Maciel M. Infectious thoracic aortitis: a literature review. Clin Cardiol. 2009;32:488-90 pubmed publisher
    Infectious thoracic aortitis (IA) remains a rare disease, especially after the appearance of antibiotics. However, if left untreated it is always lethal...
  2. Chirinos J, Tamariz L, Lopes G, Del Carpio F, Zhang X, Milikowski C, et al. Large vessel involvement in ANCA-associated vasculitides: report of a case and review of the literature. Clin Rheumatol. 2004;23:152-9 pubmed
    ..Here, we report a case of fatal aortitis and aortic dissection in a patient with microscopic polyangiitis and review reported cases of large vessel ..
  3. Chowdhary V, Crowson C, Liang K, Michet C, Miller D, Warrington K, et al. Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study. Arthritis Res Ther. 2009;11:R29 pubmed publisher
    Idiopathic aortitis is a rare condition characterized by giant cell or lymphoplasmacytic inflammation of the aorta. The purpose of this study was to describe risk factors for the development of idiopathic aortitis...
  4. Agaimy A, Weyand M, Strecker T. Inflammatory thoracic aortic aneurysm (lymphoplasmacytic thoracic aortitis): a 13-year-experience at a German Heart Center with emphasis on possible role of IgG4. Int J Clin Exp Pathol. 2013;6:1713-22 pubmed
    ..IgG4-rich sclerosing lymphoplasmacytic thoracic aortitis is a constant histological feature of thoracic IAA...
  5. Pacini D, Leone O, Turci S, Camurri N, Giunchi F, Martinelli G, et al. Incidence, etiology, histologic findings, and course of thoracic inflammatory aortopathies. Ann Thorac Surg. 2008;86:1518-23 pubmed publisher
    The aims of this study were to detect the incidence of thoracic histologically proven aortitis in a large series of 788 patients operated on for thoracic aortic disease, to describe the surgical and histologic features of inflammatory ..
  6. Choi J, Yang H, Oh S, Yun K. Rupture of ascending aorta secondary to tuberculous aortitis. Ann Thorac Surg. 2003;75:1965-7 pubmed
    Tuberculous aortitis generally develops at the distal aortic arch and the descending aorta that are close to specific groups of mediastinal lymph nodes, but exceptionally it develops in the ascending aorta...
  7. Lee S, Lim S, Kim D, Joo H. Acupuncture induced necrotizing aortitis with infected pseudoaneurysm formation. Yonsei Med J. 2008;49:322-4 pubmed publisher
    Necrotizing aortitis is a rare and life-threatening complication of local or generalized bacterial infections and most commonly affects the abdominal aorta...
  8. Narvaez J, Narvaez J, Nolla J, Sirvent E, Reina D, Valverde J. Giant cell arteritis and polymyalgia rheumatica: usefulness of vascular magnetic resonance imaging studies in the diagnosis of aortitis. Rheumatology (Oxford). 2005;44:479-83 pubmed
    ..giant cell (temporal) arteritis (GCA) is the detection and monitoring of large-artery complications, particularly aortitis. Recent investigations support vascular magnetic resonance imaging (MRI) studies in this issue...
  9. Seder C, Kramer M, Long G, Uzieblo M, Shanley C, Bove P. Clostridium septicum aortitis: Report of two cases and review of the literature. J Vasc Surg. 2009;49:1304-9 pubmed publisher
    Clostridium septicum aortitis is a rare infection that has a strong association with occult colonic malignancy...
  10. Takagi H, Mori Y, Iwata H, Kimura M, Itokazu M, Shimokawa K, et al. Nondissecting aneurysm of the thoracic aorta with arteritis in systemic lupus erythematosus. J Vasc Surg. 2002;35:801-4 pubmed
    ..These findings would have been in accordance with active aortitis. Systemic lupus erythematosus was suggested as possibly associated with nondissecting thoracic aortic aneurysm, ..
  11. Burian K, Berencsi K, Endresz V, Gyulai Z, Valyi Nagy T, Valyi Nagy I, et al. Chlamydia pneumoniae exacerbates aortic inflammatory foci caused by murine cytomegalovirus infection in normocholesterolemic mice. Clin Diagn Lab Immunol. 2001;8:1263-6 pubmed
    ..The early foci induced by virus infection were significantly exacerbated following a single inoculation with Chlamydia pneumoniae. ..
  12. Wein M, Bartel T, Kabatnik M, Sadony V, Dirsch O, Erbel R. Rapid progression of bacterial aortitis to an ascending aortic mycotic aneurysm documented by transesophageal echocardiography. J Am Soc Echocardiogr. 2001;14:646-9 pubmed
    A case of bacterial aortitis of the ascending aorta caused by Staphylococcus aureus progressed to an aortic mycotic aneurysm. Transesophageal echocardiography was the diagnostic approach of choice...
  13. Miller D, Isotalo P, Weyand C, Edwards W, Aubry M, Tazelaar H. Surgical pathology of noninfectious ascending aortitis: a study of 45 cases with emphasis on an isolated variant. Am J Surg Pathol. 2006;30:1150-8 pubmed
    b>Aortitis is emerging as an important cause of ascending aortic aneurysm in the elderly. Its features have not been described in a surgical population...
  14. Homme J, Aubry M, Edwards W, Bagniewski S, Shane Pankratz V, Kral C, et al. Surgical pathology of the ascending aorta: a clinicopathologic study of 513 cases. Am J Surg Pathol. 2006;30:1159-68 pubmed
    ..cystic medial degeneration (CMD) in 209, aortic dissection (AD) in 109 (with CMD in 56), normal media in 90, aortitis in 57 (with CMD in 14), and other findings in 48...
  15. Maillet J, Palombi T, Sablayrolles J, Bonnet N. Septic rupture of an atherosclerotic plaque of the ascending aorta. Interact Cardiovasc Thorac Surg. 2012;15:790-1 pubmed
    Infectious aortitis has become a rare disease thanks to the widespread use of antibiotics...
  16. Narang A, Rathlev N. Non-aneurysmal infectious aortitis: a case report. J Emerg Med. 2007;32:359-63 pubmed
    Infectious aortitis is a rare clinical entity that is most often associated with an abdominal aortic aneurysm. There have been very few documented cases of aortitis in the setting of a normal-sized caliber aorta...
  17. Tavora F, Burke A. Review of isolated ascending aortitis: differential diagnosis, including syphilitic, Takayasu's and giant cell aortitis. Pathology. 2006;38:302-8 pubmed
    ..We discuss the differential diagnosis of syphilitic aortitis, Takayasu's disease, and giant cell aortitis, with a review of the literature and brief overview of other types ..
  18. Vaglio A, Buzio C. Chronic periaortitis: a spectrum of diseases. Curr Opin Rheumatol. 2005;17:34-40 pubmed
    ..Its clinical course is chronic-relapsing, so a careful follow-up is essential. Further studies are needed to investigate the pathogenetic mechanisms and the most appropriate therapeutic options. ..
  19. Yang Z, Reilly S. Clostridium septicum aortitis causing aortic dissection in a 22-year-old man. Tex Heart Inst J. 2009;36:334-6 pubmed
    ..Only 26 cases of C. septicum aortitis have been reported; all of those patients were elderly, and 20 of them had an associated colonic neoplasm...
  20. Stone J. Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of IgG4-related systemic disease. Curr Opin Rheumatol. 2011;23:88-94 pubmed publisher
    ..This review will focus on IgG4-related systemic disease as a cause of thoracic aortitis, inflammatory abdominal aortic aneurysm or periaortitis, and retroperitoneal fibrosis...
  21. Cevasco M, Menard M, Bafford R, McNamee C. Acute infectious pseudoaneurysm of the descending thoracic aorta and review of infectious aortitis. Vasc Endovascular Surg. 2010;44:697-700 pubmed publisher
    ..A literature review of mycotic thoracic aortic aneurysms and pseudoaneurysms is also presented...
  22. Butler N, Mundy J, Shah P. Aortic complications of giant cell arteritis: a diagnostic and management dilemma. J Card Surg. 2010;25:572-81 pubmed publisher
    We describe three giant cell aortitis patients who were operatively managed at our institution over the last seven years and review the recent relevant literature to highlight the specific features of the disease and the salient points of ..
  23. Schubl S, TSAI S, Ryer E, Wang C, Hu J, Kent K, et al. Upregulation of protein kinase cdelta in vascular smooth muscle cells promotes inflammation in abdominal aortic aneurysm. J Surg Res. 2009;153:181-7 pubmed publisher
    ..These findings, coupled with earlier studies of PKCdelta, suggest that PKCdelta plays a central role in the pathogenesis of AAAs and may be a potential target for future therapies. ..
  24. Hountis P, Dedeilias P, Vourlakou C, Bolos K. Isolated bilateral coronary artery ostial stenosis in aortitis syndrome. Hellenic J Cardiol. 2010;51:472-4 pubmed
    ..The patient's history was not significant for systemic diseases. The aorta had prominent signs of aortitis of unknown etiology, possibly due to a chronic mycotic process...
  25. Huang J, Ho A, Ahmed A, Bhalla S, Menias C. Borne identity: CT imaging of vascular infections. Emerg Radiol. 2011;18:335-43 pubmed publisher
    ..pictorial review aims to discuss and illustrate the CT findings of the following vascular infections including aortitis, mycotic aneurysms, infective endocarditis, septic thrombophlebitis in the chest and abdomen, and Kawasaki ..
  26. Lin M, Cheng H. Images in cardiovascular medicine: tuberculous aortitis. Intern Med. 2012;51:1983-5 pubmed
    Tuberculous aortitis is a rare disease entity indicative of disseminated tuberculosis. We report a case who presented with newly diagnosed hypertension one year after her last admission for pulmonary and pericardial tuberculosis...
  27. Emami H, Vijayakumar J, Subramanian S, Vucic E, Singh P, Macnabb M, et al. Arterial 18F-FDG uptake in rheumatoid arthritis correlates with synovial activity. JACC Cardiovasc Imaging. 2014;7:959-60 pubmed publisher
  28. Domenech E, Garcia Planella E, Olazábal A, Sanchez Delgado J, Zabana Y, Bernal I, et al. Abdominal aortitis associated with Crohn's disease. Dig Dis Sci. 2005;50:1122-3 pubmed
  29. Kimura N, Yamaguchi A, Noguchi K, Adachi K, Adachi H, Ino T. Type B aortic dissection associated with Salmonella infection. Gen Thorac Cardiovasc Surg. 2007;55:212-6 pubmed
    ..In this case, it is believed that insidious Salmonella aortitis caused acute type B aortic dissection.
  30. Abdelbaky A, Corsini E, Figueroa A, Fontanez S, Subramanian S, Ferencik M, et al. Focal arterial inflammation precedes subsequent calcification in the same location: a longitudinal FDG-PET/CT study. Circ Cardiovasc Imaging. 2013;6:747-54 pubmed publisher
    ..Here, we provide first-in-man evidence that arterial inflammation precedes subsequent Ca deposition, a marker of plaque progression, within the underlying location in the artery wall. ..
  31. Hoffman G. Determinants of vessel targeting in vasculitis. Clin Dev Immunol. 2004;11:275-9 pubmed
    ..differences exist in regions of the aorta that determine vulnerability to diseases, such as atherosclerosis, aortitis, giant cell arteritis and Takayasu's disease...
  32. Raff G, Gray B, Torres A, Hasselman T. Aortitis in a child with Abiotrophia defectiva endocarditis. Pediatr Infect Dis J. 2004;23:574-6 pubmed
    ..We describe an unusual case complicated by extensive aortitis with pits in the ascending aorta and the proximal aortic arch.
  33. Darie C, Boutalba S, Fichter P, Huret J, Jaillot P, Deplus F, et al. [Aortitis after G-CSF injections]. Rev Med Interne. 2004;25:225-9 pubmed
    b>Aortitis consists in aortic wall inflammation from infectious or non infectious cause. It may lead to aortic aneurysm with a risk of rupture, which is life-threatening and may justify surgical procedures...
  34. Löffler C, Hoffend J, Benck U, Krämer B, Bergner R. The value of ultrasound in diagnosing extracranial large-vessel vasculitis compared to FDG-PET/CT: A retrospective study. Clin Rheumatol. 2017;36:2079-2086 pubmed publisher
    ..GCA), Takayasu arteritis, and a series of rare diseases like Behçet's disease, IgG4-related disease, infectious aortitis, and other unfrequent entities...
  35. Rivero Marcotegui M, Maravi Petri C, Barba Cosials J, Hernández Palacios R, Sanchez Alvarez J. [Fever of unknown origin and tuberculous aortitis]. An Med Interna. 1994;11:546-8 pubmed
  36. Ben Jmaa H, Karray R, Jmal H, Chérif T, Dhouib F, Souissi I, et al. [Surgical and endoluminal management of the inflammatory aortitis: A Tunisian center experience]. J Med Vasc. 2017;42:213-220 pubmed publisher
    Non-infectious aortitis is usually due to giant-cell arteritis, Takayasu disease or Behçet disease...
  37. Chaudet A, Goujon J, Ghazali A. Febrile abdominal pain revealing Horton's disease. Am J Emerg Med. 2017;35:1583.e3-1583.e5 pubmed publisher
    ..It can affect extracranial large vessels but only rarely the aorta. Diagnosis of aortitis is difficult and its incidence is probably underestimated...
  38. Gasparovic H, Djuric Z, Bosnic D, Petricevic M, Brida M, Dotlic S, et al. Aortic root vasculitis associated with Cogan's syndrome. Ann Thorac Surg. 2011;92:340-1 pubmed publisher
    ..a patient with progressive congestive heart failure due to massive aortic and mitral insufficiency coupled with aortitis leading to an ascending aortic aneurysm...
  39. Elourimi G, Soussan M, Warzocha U, Bugaud H, Dhote R, Abad S. Efficacy of tocilizumab highlighted by FDG-PET/CT in a patient with relapsing polychondritis-associated aortitis. Rheumatol Int. 2017;37:1931-1935 pubmed publisher
    ..We report the case of a woman with a corticosteroid-resistant RP-associated aortitis, who was successfully treated with tocilizumab (TCZ)...
  40. Laudito A, Gai V, Battista S, Garabello D, Limerutti G, Rinaldi M. Images in cardiovascular medicine. Clostridium septicum arch aortitis. Circulation. 2008;117:1609 pubmed publisher
  41. Hsu C, Huang Y, Chuang Y. Detection of an infected abdominal aortic aneurysm with three-phase bone scan and gallium-67 scan. Clin Nucl Med. 2008;33:305-7 pubmed publisher
    ..The previously unsuspected infected abdominal aortic aneurysm was confirmed by computed tomography. ..
  42. Zenati M, Bonanomi G, Kostov D, Lee R. Images in cardiovascular medicine. Fulminant Clostridium septicum aortitis. Circulation. 2002;105:1871 pubmed
  43. Kasashima S, Zen Y. IgG4-related inflammatory abdominal aortic aneurysm. Curr Opin Rheumatol. 2011;23:18-23 pubmed publisher
  44. Murakami S, Saito H, Ohe M, Kondo T, Oshita F, Yamada K. Periaortitis associated with anti-neutrophil cytoplasmic antibodies induced by bevacizumab combination therapy. Intern Med. 2013;52:589-91 pubmed
    ..A noninfectious fever occurring during chemotherapy might be a sign of vasculitis; therefore, we must ensure that possible periaortitis is not overlooked. ..
  45. Dhareshwar J, Estrera A, Covinsky M, Safi H. Inflammatory aneurysm of the ascending aorta. Eur J Cardiothorac Surg. 2006;30:806-7 pubmed
    ..Inflammatory aneurysms of the aorta are usually seen in the infrarenal abdominal aorta and very rarely in the ascending aorta. We present the case of a 76-year-old male with inflammatory aneurysm of the ascending aorta. ..
  46. Roberts W, Ko J, Moore T, Jones W. Causes of pure aortic regurgitation in patients having isolated aortic valve replacement at a single US tertiary hospital (1993 to 2005). Circulation. 2006;114:422-9 pubmed
    ..aorta: dissection, 28 patients (19%); the Marfan syndrome or its forme fruste variety, 15 patients (10%); aortitis, 12 patients (8%), and in the remaining 91 patients (62%), the cause of the AR was not determined...
  47. Hirose H, Cassano A, Youdelman B, Hou J, Strong M. Inflammatory aneurysm of the descending aorta: a case report. Heart Surg Forum. 2005;8:E431-3 pubmed
    ..We report a rare case of an inflammatory descending aneurysm. At surgery, the patient had multiple aneurysms on the descending aorta. Histology of the specimen demonstrated an infiltration of chronic inflammatory cells in the aortic media. ..
  48. Fiessinger J, Paul J. [Inflammatory and infectious aortitis]. Rev Prat. 2002;52:1094-9 pubmed
    Takayasu's disease is the most characteristic example of aortitis. Non-specific aortoarteritis is the only one with stenotic lesions of the aorta. Ischemic symptoms depend of the arterial lesions...
  49. Lopez F, Vaidyan P, Mega A, Schiffman F. Aortitis as a manifestation of myelodysplastic syndrome. Postgrad Med J. 2001;77:116-8 pubmed
    b>Aortitis is the inflammation of the wall of the aorta and can occur from an infection or autoimmune disease. Myelodysplastic syndrome (MDS) is characterised by abnormal haematopoiesis and a dysfunctional immune system...
  50. Holubec T, Laco J, Holubcová Z, Vojacek J, Dominik J, Steiner I, et al. Repair of thoracic aortic aneurysm due to noninfectious aortitis. J Card Surg. 2012;27:199-204 pubmed publisher
    Isolated thoracic aortitis (ITA) is a newly-defined pathological entity with a still-unknown etiopathology and with some potential relationship to IgG4-related systemic disease...
  51. Czihal M, Forster S, Hoffmann U. [Imaging diagnostics of large vessel vasculitis]. Radiologe. 2010;50:855-60 pubmed publisher
    ..To date the diagnostic benefit of combined PET and morphological imaging (PET-CT) as well as the value of imaging procedures in order to assess disease activity and therapy control remain unclear. ..
  52. Tseng C, Tsai J, Chen C. Abdominal aortitis associated with autoimmune pancreatitis. Clin Gastroenterol Hepatol. 2009;7:e3-4 pubmed publisher
  53. Brodmann M, Lipp R, Aigner R, Pilger E. Positron emission tomography reveals extended thoracic and abdominal peri-aortitis. Vasc Med. 2003;8:127-8 pubmed