peritoneal cavity


Summary: The space enclosed by the peritoneum. It is divided into two portions, the greater sac and the lesser sac or omental bursa, which lies behind the STOMACH. The two sacs are connected by the foramen of Winslow, or epiploic foramen.

Top Publications

  1. Corona R, Verguts J, Koninckx R, Mailova K, Binda M, Koninckx P. Intraperitoneal temperature and desiccation during endoscopic surgery. Intraoperative humidification and cooling of the peritoneal cavity can reduce adhesions. Am J Obstet Gynecol. 2011;205:392.e1-7 pubmed publisher
    ..With a modified humidifier, desiccation could be eliminated while maintaining the intraperitoneal temperature between 31 to 32°C...
  2. Le S, Gongora M, Zhang B, Grimmond S, Campbell G, Campbell J, et al. Gene expression profile of the fibrotic response in the peritoneal cavity. Differentiation. 2010;79:232-43 pubmed publisher
    The cellular response to materials implanted in the peritoneal cavity has been utilised to produce tissue for grafting to hollow smooth muscle organs (blood vessels, bladder, uterus and vas deferens)...
  3. Shin N, Kim M, Chung J, Chung Y, Choi J, Park Y. The differential imaging features of fat-containing tumors in the peritoneal cavity and retroperitoneum: the radiologic-pathologic correlation. Korean J Radiol. 2010;11:333-45 pubmed publisher
    ..Classifying lesions in terms of the necessity of performing surgical treatment can provide important information to clinicians, and this is the one of a radiologist's key responsibilities...
  4. Jamur M, Moreno A, Mello L, Souza Júnior D, Campos M, Pastor M, et al. Mast cell repopulation of the peritoneal cavity: contribution of mast cell progenitors versus bone marrow derived committed mast cell precursors. BMC Immunol. 2010;11:32 pubmed publisher
    ..This study was undertaken to determine the mast cell response in the peritoneal cavity and bone marrow during repopulation of the peritoneal cavity in rats.
  5. Fan C, Zhang D, Zhang C. On sample size of the kruskal-wallis test with application to a mouse peritoneal cavity study. Biometrics. 2011;67:213-24 pubmed publisher
    ..A mouse peritoneal cavity study is used to demonstrate the application of the methods.
  6. Vale A, Tanner J, Schelonka R, Zhuang Y, Zemlin M, Gartland G, et al. The peritoneal cavity B-2 antibody repertoire appears to reflect many of the same selective pressures that shape the B-1a and B-1b repertoires. J Immunol. 2010;185:6085-95 pubmed publisher
    ..assess the extent and nature of somatic categorical selection of CDR-3 of the Ig H chain (CDR-H3) content in peritoneal cavity (PerC) B cells, we analyzed the composition of V(H)7183DJC? transcripts derived from sorted PerC B-1a, B-1b, ..
  7. Brand A, De Kwaadsteniet M, Dicks L. The ability of nisin F to control Staphylococcus aureus infection in the peritoneal cavity, as studied in mice. Lett Appl Microbiol. 2010;51:645-9 pubmed publisher
    ..To determine the ability of nisin F to control systematic infection caused by Staphylococcus aureus, using C57BL/6 mice as a model...
  8. Ishii M, Kato C, Hakamata A, Kojima N. Targeting with oligomannose-coated liposomes promotes maturation and splenic trafficking of dendritic cells in the peritoneal cavity. Int Immunopharmacol. 2011;11:164-71 pubmed publisher
    ..Both types of cells rapidly took up OMLs in the peritoneal cavity, but only CD11b(dull)CD11c(+) cells produced interleukin (IL)-12 in response to OML uptake...
  9. Budzynski A, Matłok M, Pedziwiatr M, Budzynski P, Tusinski M, Zub Pokrowiecka A, et al. SILS (single incision laparoscopic surgery) - new surgical approach to peritoneal cavity. Adv Med Sci. 2011;56:18-24 pubmed publisher
    ..During the last years we can observe an intense development of surgical technique minimizing the access to peritoneal cavity to just one small incision, most frequently localized in the umbilicus.

More Information


  1. Gupta N, Rajwanshi A, Dey P, Suri V. Adult granulosa cell tumor presenting as metastases to the pleural and peritoneal cavity. Diagn Cytopathol. 2012;40:912-5 pubmed publisher
    ..A precise diagnosis in such a case may be possible on serous body fluid cytology with a combined clinical and cytopathologic approach...
  2. Poland C, Byrne F, Cho W, Prina Mello A, Murphy F, Davies G, et al. Length-dependent pathogenic effects of nickel nanowires in the lungs and the peritoneal cavity. Nanotoxicology. 2012;6:899-911 pubmed publisher
    ..This may have important implications when considering the hazard posed by fibrous nanomaterials and their regulation in workplaces...
  3. Parra D, Rieger A, Li J, Zhang Y, Randall L, Hunter C, et al. Pivotal advance: peritoneal cavity B-1 B cells have phagocytic and microbicidal capacities and present phagocytosed antigen to CD4+ T cells. J Leukoc Biol. 2012;91:525-36 pubmed publisher
    ..In a broader context, these newly identified capacities of B-1 B cells further support the previously recognized functional, developmental, and evolutionary relationships between these cells and macrophages...
  4. Fieren M. The local inflammatory responses to infection of the peritoneal cavity in humans: their regulation by cytokines, macrophages, and other leukocytes. Mediators Inflamm. 2012;2012:976241 pubmed publisher
  5. Brisslert M, Amu S, Pullerits R. Intra-peritoneal sRAGE treatment induces alterations in cellular distribution of CD19(+), CD3 (+) and Mac-1 (+) cells in lymphoid organs and peritoneal cavity. Cell Tissue Res. 2013;351:139-48 pubmed publisher
    ..Mice treated with sRAGE displayed an increased leucocyte count in the peritoneal cavity, enlarged spleens and increased cellularity compared with vehicle-treated animals...
  6. Yilmaz M, Akbulut S, Kahraman A, Yilmaz S. Liver hydatid cyst rupture into the peritoneal cavity after abdominal trauma: case report and literature review. Int Surg. 2012;97:239-44 pubmed publisher
    ..Rupture of a hydatid cyst into the peritoneal cavity is rare and challenging for the surgeon...
  7. Wang H, Xing Y, Mao L, Luo Y, Kang L, Meng G. Pannexin-1 influences peritoneal cavity cell population but is not involved in NLRP3 inflammasome activation. Protein Cell. 2013;4:259-65 pubmed publisher
    ..Our study thus reveals an important role for Panx1 in regulation of peritoneal cell population and peritonitis development...
  8. Jacobs Tulleneers Thevissen D, Chintinne M, Ling Z, Gillard P, Schoonjans L, Delvaux G, et al. Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient. Diabetologia. 2013;56:1605-14 pubmed publisher
    ..This study examined in immunodeficient mice whether alginate-encapsulated graft function was inferior to that of free grafts of the same size and composition...
  9. Margry B, Wieland W, van Kooten P, van Eden W, Broere F. Peritoneal cavity B-1a cells promote peripheral CD4+ T-cell activation. Eur J Immunol. 2013;43:2317-26 pubmed publisher
    ..Using combined adoptive transfer experiments with peptide-pulsed peritoneal cavity (PerC)-derived B-1a cells and CFSE-labeled T cells, we show that B-1a cells present Ag to CD4(+) T cells ..
  10. de Almeida Buranello P, Moulin M, Souza D, Jamur M, Roque Barreira M, Oliver C. The lectin ArtinM induces recruitment of rat mast cells from the bone marrow to the peritoneal cavity. PLoS ONE. 2010;5:e9776 pubmed publisher
    ..The D-mannose binding lectin ArtinM is known to recruit neutrophils, to degranulate mast cells and may have potential therapeutic applications. However, the effect of ArtinM on mast cell recruitment has not been investigated...
  11. Maseda D, Candando K, Smith S, Kalampokis I, Weaver C, Plevy S, et al. Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-?+CD4+ T cell numbers during colitis development in mice. J Immunol. 2013;191:2780-2795 pubmed publisher
    ..However, the peritoneal cavity also contains relatively high frequencies of functionally defined IL-10-competent B10 cells...
  12. Hamaguchi Y, Uchida J, Cain D, Venturi G, Poe J, Haas K, et al. The peritoneal cavity provides a protective niche for B1 and conventional B lymphocytes during anti-CD20 immunotherapy in mice. J Immunol. 2005;174:4389-99 pubmed
    ..By contrast, peritoneal cavity B cells expressed normal CD20 densities and were coated with CD20 mAb, but only 30-43% of B1 cells and 43-78%..
  13. Sorensen E, Gerber S, Sedlacek A, Rybalko V, Chan W, Lord E. Omental immune aggregates and tumor metastasis within the peritoneal cavity. Immunol Res. 2009;45:185-94 pubmed publisher
  14. Leite A, Cunha F, Dal Secco D, Fukada S, Girão V, Rocha F. Effects of nitric oxide on neutrophil influx depends on the tissue: role of leukotriene B4 and adhesion molecules. Br J Pharmacol. 2009;156:818-25 pubmed publisher
    ..We investigated the effect of nitric oxide synthase (NOS) inhibition on polymorphonuclear cell (PMN) influx in zymosan or lipopolysaccharide (LPS)-induced arthritis and peritonitis...
  15. Roberts G, Baird D, Gallagher K, Jones R, Pepper C, Williams J, et al. Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysis. J Am Soc Nephrol. 2009;20:1895-900 pubmed publisher
    ..We found that functional effector memory T cells capable of mounting long-term recall responses enrich the peritoneal cavity of PD patients...
  16. Xing Y, Li W, Lin Y, Fu M, Li C, Zhang P, et al. The influence of BCR density on the differentiation of natural poly-reactive B cells begins at an early stage of B cell development. Mol Immunol. 2009;46:1120-8 pubmed publisher
    ..More importantly, our data suggests that the influence by receptor expression on the differentiation of natural poly-reactive B cells begins at an early stage of B cell development...
  17. Sumiyama K, Tajiri H, Gostout C. Submucosal endoscopy with mucosal flap safety valve (SEMF) technique: a safe access method into the peritoneal cavity and mediastinum. Minim Invasive Ther Allied Technol. 2008;17:365-9 pubmed publisher
    ..The methods and technology growing from this concept may minimize trauma from surgical access to the peritoneal cavity by completely eliminating body surface incisions...
  18. Voermans R, Sheppard B, van Berge Henegouwen M, Fockens P, Faigel D. Comparison of Transgastric NOTES and laparoscopic peritoneoscopy for detection of peritoneal metastases. Ann Surg. 2009;250:255-9 pubmed publisher
    ..Transgastric peritoneoscopy (TGP) may be a future alternative to the diagnostic laparoscopy (LAP)...
  19. Zhang Z, Xi T, Wang Y, Chen X, Zhang J, Wang C, et al. In vitro study of endothelial cells lining vascular grafts grown within the recipient's peritoneal cavity. Tissue Eng Part A. 2008;14:1109-20 pubmed publisher
    ..Careful design of the bioreactor and careful selection of the culture conditions will greatly improve the chances of producing a useful anti-thrombogenic surface for tissue-engineered small-diameter vessels...
  20. Berberich S, Dähne S, Schippers A, Peters T, Muller W, Kremmer E, et al. Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots. J Immunol. 2008;180:2196-203 pubmed
    The constitutive migration of B cells from the circulation into the peritoneal cavity and back is essential for peritoneal B cell homeostasis and function...
  21. Cao Y, Zhang B, Croll T, Rolfe B, Campbell J, Campbell G, et al. Engineering tissue tubes using novel multilayered scaffolds in the rat peritoneal cavity. J Biomed Mater Res A. 2008;87:719-27 pubmed publisher
    ..on the inside and outside surfaces of the scaffolds were observed, none of these biomolecule coatings was able to overcome the foreign body response within the peritoneal cavity, even in the presence of a nonadsorptive HA undercoat.
  22. Ohnmacht C, Pullner A, Van Rooijen N, Voehringer D. Analysis of eosinophil turnover in vivo reveals their active recruitment to and prolonged survival in the peritoneal cavity. J Immunol. 2007;179:4766-74 pubmed
    ..These results demonstrate that the peritoneum serves as reservoir for eosinophils...
  23. Zuinen R, Yamaji K, Aoki M, Chikuma T, Hojo H. Early induced, high-level interleukin-6 expression in the rat peritoneal cavity into which a hepatotoxicant carbon tetrachloride was administered. Toxicol Lett. 2007;170:42-8 pubmed
    ..of CCl4 dissolved in a small amount of vehicle selectively induces a high production of IL-6 in the peritoneal cavity early after the administration...
  24. Peeters P, Aerssens J, de Hoogt R, Stanisz A, Göhlmann H, Hillsley K, et al. Molecular profiling of murine sensory neurons in the nodose and dorsal root ganglia labeled from the peritoneal cavity. Physiol Genomics. 2006;24:252-63 pubmed
    ..calcium channels; and transient receptor potential cation channels present in afferents projecting to the peritoneal cavity. Our genome-wide expression profiling data provide novel insight into molecular signatures that underlie ..
  25. Van Dijk C, Ledesma S, Teitelbaum I. Patient characteristics associated with defects of the peritoneal cavity boundary. Perit Dial Int. 2005;25:367-73 pubmed
    Conflicting literature exist regarding the patient characteristics that may confer an increased risk for anatomic complications of the peritoneal cavity boundaries.
  26. Ito H, Ninomiya A, Furuuchi T, Hagiwara M, Kanai K, Kodaira K, et al. [A case of intravesical foreign body with a vesical rupture invading the peritoneal cavity: a case report]. Hinyokika Kiyo. 2009;55:425-7 pubmed
    ..We performed open surgery, and found the urinary bladder to be perforated by a foreign body which invaded the peritoneal cavity. To our knowledge, there were 10 similar cases in Japan.
  27. Binda M, Koninckx P. Prevention of adhesion formation in a laparoscopic mouse model should combine local treatment with peritoneal cavity conditioning. Hum Reprod. 2009;24:1473-9 pubmed publisher
    ..This process can be enhanced by factors derived from the peritoneal cavity such as mesothelial cell hypoxia (pneumoperitoneum with pure CO(2)), reactive oxygen species (..
  28. Joshipura V, Haribhakti S, Patel N, Naik R, Soni H, Patel B, et al. A prospective randomized, controlled study comparing low pressure versus high pressure pneumoperitoneum during laparoscopic cholecystectomy. Surg Laparosc Endosc Percutan Tech. 2009;19:234-40 pubmed publisher
    ..Laparoscopic cholecystectomy can be performed at low pressure pneumoperitoneum. However, available space for dissection is less than the high pressure pneumoperitoneum...
  29. Mebius R. Lymphoid organs for peritoneal cavity immune response: milky spots. Immunity. 2009;30:670-2 pubmed publisher
    Milky spots are located in the omentum of the peritoneal cavity and their classification as lymphoid organs has been debated. In this issue of Immunity, Rangel-Moreno et al...
  30. Zhao Z, Liu S, Li Z, Hou J, Wang Z, Ma X, et al. Sectional anatomy of the peritoneal reflections of the upper abdomen in the coronal plane. J Comput Assist Tomogr. 2005;29:430-7 pubmed
    ..The purpose of this study was to provide practical anatomic data for the imaging diagnosis and surgical treatment of the diseases of the subphrenic spaces...
  31. Yan T, Black D, Savady R, Sugarbaker P. Systematic review on the efficacy of cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis from colorectal carcinoma. J Clin Oncol. 2006;24:4011-9 pubmed
    ..The efficacy of cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for patients with peritoneal carcinomatosis from colorectal carcinoma remains to be established...
  32. Vizzini A, Vazzana M, Cammarata M, Parrinello N. Peritoneal cavity phagocytes from the teleost sea bass express a glucocorticoid receptor (cloned and sequenced) involved in genomic modulation of the in vitro chemiluminescence response to zymosan. Gen Comp Endocrinol. 2007;150:114-23 pubmed
    ..In situ hybridization assay revealed that DlGR1 was expressed in macrophages and neutrophils from the peritoneal cavity. Since in a previous paper, sea bass PCL chemiluminescence response (CL) has been related to increased ..
  33. Rippe A, Rippe C, Swärd K, Rippe B. Disproportionally low clearance of macromolecules from the plasma to the peritoneal cavity in a mouse model of peritoneal dialysis. Nephrol Dial Transplant. 2007;22:88-95 pubmed
    ..This study was performed to establish a model for quantitative measurements of a number of basic peritoneal transport parameters, particularly transperitoneal clearances (Cl) of macromolecules, during mouse peritoneal dialysis...
  34. Fukumoto Y, Ikeguchi M, Matsumoto S, Inoue M, Osaki T, Fukuda K, et al. Detection of cancer cells and gene expression of cytokines in the peritoneal cavity in patients with gastric cancer. Gastric Cancer. 2006;9:271-6 pubmed
    The gene expression of the cytokines interleukin-2 (IL-2) and IL-10 in peritoneal washings was examined in relation to the presence of cancer cells in the peritoneal cavity in patients with gastric cancer.
  35. Olszewski W, Kubicka U, Tarnowski W, Bielecki K, Ziolkowska A, Wesolowska A. Activation of human peritoneal immune cells in early stages of gastric and colon cancer. Surgery. 2007;141:212-21 pubmed
    ..We investigated mobilization of immune cells in peritoneal fluid of gastric and colon cancer, phenotypes and level of activation of recruited cells, and concentration of cellular and peritoneal fluid cytokines...
  36. Berberich S, Forster R, Pabst O. The peritoneal micromilieu commits B cells to home to body cavities and the small intestine. Blood. 2007;109:4627-34 pubmed
    ..Here we report that exposure of naive B cells to the microenvironment of the peritoneal cavity modulates their migration propensities in the absence of antigenic stimulation...
  37. Ksiazek K, Korybalska K, Jorres A, Witowski J. Accelerated senescence of human peritoneal mesothelial cells exposed to high glucose: the role of TGF-beta1. Lab Invest. 2007;87:345-56 pubmed
  38. Kantsevoy S, Jagannath S, Niiyama H, Isakovich N, Chung S, Cotton P, et al. A novel safe approach to the peritoneal cavity for per-oral transgastric endoscopic procedures. Gastrointest Endosc. 2007;65:497-500 pubmed
    ..We have previously reported the feasibility and safety of per-oral transgastric endoscopic procedures in a porcine model...
  39. Refeidi A. Live Ascaris lumbricoides in the peritoneal cavity. Ann Saudi Med. 2007;27:118-21 pubmed
  40. Yonemura Y, Kawamura T, Bandou E, Tsukiyama G, Endou Y, Miura M. The natural history of free cancer cells in the peritoneal cavity. Recent Results Cancer Res. 2007;169:11-23 pubmed
  41. von Delius S, Feussner H, Wilhelm D, Karagianni A, Henke J, Schmid R, et al. Transgastric in vivo histology in the peritoneal cavity using miniprobe-based confocal fluorescence microscopy in an acute porcine model. Endoscopy. 2007;39:407-11 pubmed
    ..Apart from its therapeutic implications, this type of access to the peritoneal cavity might also be useful for targeted in vivo histological investigation by means of confocal fluorescence ..
  42. Tanimoto N, Terasawa M, Nakamura M, Kegai D, Aoshima N, Kobayashi Y, et al. Involvement of KC, MIP-2, and MCP-1 in leukocyte infiltration following injection of necrotic cells into the peritoneal cavity. Biochem Biophys Res Commun. 2007;361:533-6 pubmed
    ..the mechanism, we used an inflammation model induced by injection of necrotic leukemic P388 cells into the peritoneal cavity in this study...
  43. Faull R. Peritoneal defensins--key contributors to the innate immunity of the peritoneal cavity?. Perit Dial Int. 2007;27:634-5 pubmed
  44. Narula V, Hazey J, Renton D, Reavis K, Paul C, Hinshaw K, et al. Transgastric instrumentation and bacterial contamination of the peritoneal cavity. Surg Endosc. 2008;22:605-11 pubmed
    ..We report the bacterial load and contamination of the peritoneal cavity in patients requiring a gastrotomy Roux-en-Y gastric bypass (LSRYGB).
  45. Lim S, Kim H, Lee K, Yoo C, Park S, Seo S. Does the use of a uterine manipulator with an intrauterine balloon in total laparoscopic hysterectomy facilitate tumor cell spillage into the peritoneal cavity in patients with endometrial cancer?. Int J Gynecol Cancer. 2008;18:1145-9 pubmed publisher
    ..Possible explanations are retrograde seeding of tumor cells into the peritoneal cavity, the pressure effect of the inflatable manipulator tip, and spillage of preexited tumor cells between the ..
  46. Campbell G, Turnbull G, Xiang L, Haines M, Armstrong S, Rolfe B, et al. The peritoneal cavity as a bioreactor for tissue engineering visceral organs: bladder, uterus and vas deferens. J Tissue Eng Regen Med. 2008;2:50-60 pubmed publisher
    ..This study shows that myofibroblast tissue produced in the peritoneal cavity is sufficiently plastic to permit differentiation of cells into bladder, vas deferens or uterine smooth ..
  47. Narula V, Happel L, Volt K, Bergman S, Roland J, Dettorre R, et al. Transgastric endoscopic peritoneoscopy does not require decontamination of the stomach in humans. Surg Endosc. 2009;23:1331-6 pubmed publisher
    ..We report the bacterial load and contamination of the peritoneal cavity in ten patients who underwent diagnostic transgastric endoscopic peritoneoscopy.
  48. von Renteln D, Eickhoff A, Kaehler G, Riecken B, Caca K. Endoscopic closure of the natural orifice transluminal endoscopic surgery (NOTES) access site to the peritoneal cavity by means of transmural resorbable sutures: an animal survival study. Endoscopy. 2009;41:154-9 pubmed publisher
    ..To date, no endoscopic technique has utilized resorbable transmural sutures for closure of the NOTES gastrostomy...
  49. Drew E, Merzaban J, Seo W, Ziltener H, McNagny K. CD34 and CD43 inhibit mast cell adhesion and are required for optimal mast cell reconstitution. Immunity. 2005;22:43-57 pubmed
    ..Our data provide clear-cut evidence for a hematopoietic function for CD34 and suggest that it acts as a negative regulator of cell adhesion...
  50. Kodera Y, Ito S, Mochizuki Y, Kondo K, Koshikawa K, Suzuki N, et al. A phase II study of radical surgery followed by postoperative chemotherapy with S-1 for gastric carcinoma with free cancer cells in the peritoneal cavity (CCOG0301 study). Eur J Surg Oncol. 2009;35:1158-63 pubmed publisher
    ..A standard treatment for such patients remains to be established...
  51. Muller J, Delos M, Panin N, Rabolli V, Huaux F, Lison D. Absence of carcinogenic response to multiwall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat. Toxicol Sci. 2009;110:442-8 pubmed publisher
    ..and cancer, these observations prompted us to explore the carcinogenic potential of these MWCNT in the peritoneal cavity of rats...
  52. Mansourian S, Sadjjadi S, Hosseini S, Barzin Z, Mehrabani D, Tanideh N, et al. Evaluation of different chemical agents on the germinative layer of sheep hydatid cyst after implantation to peritoneal cavity of BALB/c. J Invest Surg. 2009;22:183-7 pubmed publisher
    ..protoscolices lead to recurrence or the recurrence is due to the remainder of the germinative layer in the peritoneal cavity. The aim of this study was in vivo evaluation of different chemical (protoscolicidal) solutions on the ..
  53. Regli A, De Keulenaer B, Singh B, Hockings L, Noffsinger B, van Heerden P. The respiratory pressure-abdominal volume curve in a porcine model. Intensive Care Med Exp. 2017;5:11 pubmed publisher
    ..4 +/-8.5 kg) received standardized anesthesia and mechanical ventilation. A latex balloon inserted in the peritoneal cavity was inflated in 1-L increments until IAP exceeded 40 cmH2O...
  54. Skuballa J, Taraschewski H, Petney T, Pfäffle M, Smales L. The avian acanthocephalan Plagiorhynchus cylindraceus (Palaeacanthocephala) parasitizing the European hedgehog (Erinaceus europaeus) in Europe and New Zealand. Parasitol Res. 2010;106:431-7 pubmed publisher
    ..2% up to 47.6%, while in New Zealand, only 1.6% (Auckland 7.9%). Most of the worms occurred inside the peritoneal cavity where they had partly degenerated...
  55. Boudreau E, Chen G, Li X, Buck K, Hitzemann R, Hickman D. Intraperitoneal catheter placement for pharmacological imaging studies in conscious mice. Lab Anim (NY). 2010;39:23-5 pubmed publisher
    ..This technique eliminates the need to remove the animal from the scanner to administer a drug through the intraperitoneal route. ..
  56. Costa W, Coimbra F, Ribeiro H, Diniz A, de Godoy A, Begnami M, et al. Safety and preliminary results of perioperative chemotherapy and hyperthermic intraperitoneal chemotherapy (HIPEC) for high-risk gastric cancer patients. World J Surg Oncol. 2012;10:195 pubmed publisher
    ..The aim of this study is to report the preliminary results of the association of perioperative chemotherapy, radical surgery and HIPEC in high-risk gastric patients in a single institution...