peritoneum

Summary

Summary: A membrane of squamous EPITHELIAL CELLS, the mesothelial cells, covered by apical MICROVILLI that allow rapid absorption of fluid and particles in the PERITONEAL CAVITY. The peritoneum is divided into parietal and visceral components. The parietal peritoneum covers the inside of the ABDOMINAL WALL. The visceral peritoneum covers the intraperitoneal organs. The double-layered peritoneum forms the MESENTERY that suspends these organs from the abdominal wall.

Top Publications

  1. Trevisan G, Rossato M, Hoffmeister C, Oliveira S, Silva C, Matheus F, et al. Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum. Eur J Pharmacol. 2013;714:332-44 pubmed publisher
    ..Collectively, our findings suggest that TRPV1 and TRPA1 stimulation in the peritoneum produces abdominal nociception that is mediated by sensory fibres activation.
  2. Young V, Brown J, Saunders P, Horne A. The role of the peritoneum in the pathogenesis of endometriosis. Hum Reprod Update. 2013;19:558-69 pubmed publisher
    ..is defined by the presence of endometrial tissue outside the uterus, most commonly attached to the pelvic peritoneum. The endometrium in women with endometriosis is reported to be altered and there is increasing evidence that the ..
  3. Keskin H, Sirin Y, Keles H, Turgut O, Ide T, Avsar A. The aromatase inhibitor letrozole reduces adhesion formation after intraperitoneal surgery in a rat uterine horn model. Eur J Obstet Gynecol Reprod Biol. 2013;167:199-204 pubmed publisher
    ..To investigate, in an experimental animal study, the effects of letrozole and tamoxifen in the reduction of adhesion formation following abdominopelvic surgery...
  4. Tarhan O, Barut I, Ozogul C, Bozkurt S, Baykara B, Bulbul M. Structural deteriorations of the human peritoneum during laparoscopic cholecystectomy. A transmission electron microscopic study. Surg Endosc. 2013;27:2744-50 pubmed publisher
    In previous studies, changes in the surface of the peritoneum during laparoscopic surgery are well defined. Nevertheless, almost all of these studies were performed on rodents via scanning electron microscopy...
  5. Sodek K, Murphy K, Brown T, Ringuette M. Cell-cell and cell-matrix dynamics in intraperitoneal cancer metastasis. Cancer Metastasis Rev. 2012;31:397-414 pubmed publisher
    ..The peritoneum is further rendered receptive to metastatic implantation and growth by myofibroblastic cell behaviors also ..
  6. Aysan E, Bektas H, Ersoz F. A new approach to postoperative peritoneal adhesions: prevention of peritoneal trauma by aloe vera gel. Eur J Obstet Gynecol Reprod Biol. 2010;149:195-8 pubmed publisher
    ..This effect is likely due not to its chemical properties but to its viscosity, providing a covering to prevent peritoneal trauma. ..
  7. Carlow D, Gold M, Ziltener H. Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells. J Immunol. 2009;183:1155-65 pubmed publisher
    ..These results extend basic understanding of omental and peritoneal cavity immunology and of how proinflammatory events occurring within the peritoneal cavity might affect adipocyte and hepatocyte metabolism. ..
  8. Nessim S, Perl J, Bargman J. The renin-angiotensin-aldosterone system in peritoneal dialysis: is what is good for the kidney also good for the peritoneum?. Kidney Int. 2010;78:23-8 pubmed publisher
    ..This brief review will describe our current state of knowledge about the role of peritoneal RAAS in peritoneal membrane damage and potential strategies to protect the membrane. ..
  9. Zhou J, Sun J, Yang C, Xie Z, Shao W, Jin H. Long-term outcomes of transvestibular vaginoplasty with pelvic peritoneum in 182 patients with Rokitansky's syndrome. Fertil Steril. 2010;94:2281-5 pubmed publisher
    To evaluate the technical feasibility and anatomical and functional outcomes of one-stage transvestibular vaginoplasty with pelvic peritoneum for the patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.
  10. Perl J, Huckvale K, Chellar M, John B, Davies S. Peritoneal protein clearance and not peritoneal membrane transport status predicts survival in a contemporary cohort of peritoneal dialysis patients. Clin J Am Soc Nephrol. 2009;4:1201-6 pubmed publisher
    ..Increased large-pore protein loss may reflect the severity of underlying cardiovascular disease, portending a poor prognosis for these patients. ..

Detail Information

Publications86

  1. Trevisan G, Rossato M, Hoffmeister C, Oliveira S, Silva C, Matheus F, et al. Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum. Eur J Pharmacol. 2013;714:332-44 pubmed publisher
    ..Collectively, our findings suggest that TRPV1 and TRPA1 stimulation in the peritoneum produces abdominal nociception that is mediated by sensory fibres activation.
  2. Young V, Brown J, Saunders P, Horne A. The role of the peritoneum in the pathogenesis of endometriosis. Hum Reprod Update. 2013;19:558-69 pubmed publisher
    ..is defined by the presence of endometrial tissue outside the uterus, most commonly attached to the pelvic peritoneum. The endometrium in women with endometriosis is reported to be altered and there is increasing evidence that the ..
  3. Keskin H, Sirin Y, Keles H, Turgut O, Ide T, Avsar A. The aromatase inhibitor letrozole reduces adhesion formation after intraperitoneal surgery in a rat uterine horn model. Eur J Obstet Gynecol Reprod Biol. 2013;167:199-204 pubmed publisher
    ..To investigate, in an experimental animal study, the effects of letrozole and tamoxifen in the reduction of adhesion formation following abdominopelvic surgery...
  4. Tarhan O, Barut I, Ozogul C, Bozkurt S, Baykara B, Bulbul M. Structural deteriorations of the human peritoneum during laparoscopic cholecystectomy. A transmission electron microscopic study. Surg Endosc. 2013;27:2744-50 pubmed publisher
    In previous studies, changes in the surface of the peritoneum during laparoscopic surgery are well defined. Nevertheless, almost all of these studies were performed on rodents via scanning electron microscopy...
  5. Sodek K, Murphy K, Brown T, Ringuette M. Cell-cell and cell-matrix dynamics in intraperitoneal cancer metastasis. Cancer Metastasis Rev. 2012;31:397-414 pubmed publisher
    ..The peritoneum is further rendered receptive to metastatic implantation and growth by myofibroblastic cell behaviors also ..
  6. Aysan E, Bektas H, Ersoz F. A new approach to postoperative peritoneal adhesions: prevention of peritoneal trauma by aloe vera gel. Eur J Obstet Gynecol Reprod Biol. 2010;149:195-8 pubmed publisher
    ..This effect is likely due not to its chemical properties but to its viscosity, providing a covering to prevent peritoneal trauma. ..
  7. Carlow D, Gold M, Ziltener H. Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells. J Immunol. 2009;183:1155-65 pubmed publisher
    ..These results extend basic understanding of omental and peritoneal cavity immunology and of how proinflammatory events occurring within the peritoneal cavity might affect adipocyte and hepatocyte metabolism. ..
  8. Nessim S, Perl J, Bargman J. The renin-angiotensin-aldosterone system in peritoneal dialysis: is what is good for the kidney also good for the peritoneum?. Kidney Int. 2010;78:23-8 pubmed publisher
    ..This brief review will describe our current state of knowledge about the role of peritoneal RAAS in peritoneal membrane damage and potential strategies to protect the membrane. ..
  9. Zhou J, Sun J, Yang C, Xie Z, Shao W, Jin H. Long-term outcomes of transvestibular vaginoplasty with pelvic peritoneum in 182 patients with Rokitansky's syndrome. Fertil Steril. 2010;94:2281-5 pubmed publisher
    To evaluate the technical feasibility and anatomical and functional outcomes of one-stage transvestibular vaginoplasty with pelvic peritoneum for the patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.
  10. Perl J, Huckvale K, Chellar M, John B, Davies S. Peritoneal protein clearance and not peritoneal membrane transport status predicts survival in a contemporary cohort of peritoneal dialysis patients. Clin J Am Soc Nephrol. 2009;4:1201-6 pubmed publisher
    ..Increased large-pore protein loss may reflect the severity of underlying cardiovascular disease, portending a poor prognosis for these patients. ..
  11. Zhang H, Liu X, Liu Y, Yi B, Yu X. Epithelial-mesenchymal transition of rat peritoneal mesothelial cells via Rhoa/Rock pathway. In Vitro Cell Dev Biol Anim. 2011;47:165-72 pubmed publisher
    ..In conclusion, the RhoA/Rock signaling pathway may mediate EMT induced by TGF-?1 in rat peritoneal mesothelial cells. The RhoA/Rock pathway may be a potential therapeutic target for the treatment of peritoneal fibrosis. ..
  12. Weiss L, Stegmayr B, Malmsten G, Tejde M, Hadimeri H, Siegert C, et al. Biocompatibility and tolerability of a purely bicarbonate-buffered peritoneal dialysis solution. Perit Dial Int. 2009;29:647-55 pubmed
    ..Additionally, it seems to have a positive effect on residual renal function. ..
  13. Huang W, Zhang D, Millard R, Wang T, Zhao T, Fan G, et al. Gene manipulated peritoneal cell patch repairs infarcted myocardium. J Mol Cell Cardiol. 2010;48:702-12 pubmed publisher
    A gene manipulated cell patch using a homologous peritoneum substrate was developed and applied after myocardial infarction to repair scarred myocardium...
  14. Kamel R. Prevention of postoperative peritoneal adhesions. Eur J Obstet Gynecol Reprod Biol. 2010;150:111-8 pubmed publisher
    ..By the end of the study, recommendations formulated for surgeons to be followed during the operations to prevent, as much as possible, the postoperative adhesions. ..
  15. Zhai Y, Chen L, Hömme M, Hackert T, Gross M, Hoffmann G, et al. Expression and function of matrix Gla protein in human peritoneal mesothelial cells. Nephrol Dial Transplant. 2010;25:3213-21 pubmed publisher
    ..MGP is expressed by HPMC and regulated by glucose, IGF1 and TGFß1. It is a potent inhibitor of calcification in vitro and may thus play a role in the regulation of peritoneal calcium homeostasis. ..
  16. Elsurer R, Afsar B, Sezer S, Ozdemir F, Haberal M. Peritoneal albumin leakage: 2 year prospective cardiovascular event occurrence and patient survival analysis. Nephrology (Carlton). 2009;14:712-5 pubmed publisher
    ..Only advanced age independently predicts the occurrence of a cardiovascular event in patients receiving PD. ..
  17. Laterza B, Baratti D, Cozzi G, Kusamura S, Oliva G, Gavazzi C, et al. Colobronchial fistula: an unusual complication after peritonectomy and hyperthermic intra-peritoneal chemotherapy (HIPEC). In Vivo. 2009;23:151-3 pubmed
    ..Colobronchial fistula is a rare and potentially lethal complication of CRS and HIPEC. A suggestive clinical picture and contrast studies allow conclusive diagnosis to be made. Surgery is a safe and effective therapeutic option. ..
  18. She W, Lo O, Fan J, Poon J, Law W. Needlescopic totally extraperitoneal hernioplasty for unilateral inguinal hernia in adult patients. Asian J Surg. 2011;34:23-7 pubmed publisher
    ..However, because this was a small cohort study, larger prospective, randomized controlled trials are required to establish the longterm benefit, safety and complications of needlescopic surgery. ..
  19. Na D, Liu F, Miao Z, Du Z, Xu H. Astragalus extract inhibits destruction of gastric cancer cells to mesothelial cells by anti-apoptosis. World J Gastroenterol. 2009;15:570-7 pubmed
    ..Gastric cancer cells induce apoptosis of HPMCs through the supernatant. Astragalus memebranaceushas inhibits this phenomenon and can be used an adjuvant chemothera-peutic agent in gastric cancer therapy. ..
  20. Mizuno T, Mizuno M, Morgan B, Noda Y, Yamada K, Okada N, et al. Specific collaboration between rat membrane complement regulators Crry and CD59 protects peritoneum from damage by autologous complement activation. Nephrol Dial Transplant. 2011;26:1821-30 pubmed publisher
    ..The membrane complement regulators (CRegs), Crry, CD55 and CD59, are expressed in the rat peritoneum, especially along the mesothelial cell layer...
  21. Yamaguchi Y, Ishigaki T, Sano K, Miyamoto K, Nomura S, Horiuchi T. Three-dimensional invasion of epithelial-mesenchymal transition-positive human peritoneal mesothelial cells into collagen gel is promoted by the concentration gradient of fibronectin. Perit Dial Int. 2011;31:477-85 pubmed publisher
    In long-term peritoneal dialysis, myofibroblast-like cells found in the interstitium of the peritoneum are assumed to be a transformed type of mesothelial cell-epithelial-mesenchymal transition-positive [EMT(+)] human peritoneal ..
  22. Patel P, West Mays J, Kolb M, Rodrigues J, Hoff C, Margetts P. Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells. Matrix Biol. 2010;29:97-106 pubmed publisher
    ..To assess the transforming growth factor (TGF) beta independent effects of PDGF, we over-expressed PDGF-B in the peritoneum of either wild-type mice (Smad3+/+) or those with a deletion of the TGFbeta signaling protein Smad3 (Smad3(-/-))...
  23. Krediet R, Coester A, Kolesnyk I, de Graaff M, Zweers M, Smit W, et al. Karl d. Nolph state of the art lecture: feasible and future options for salvation of the peritoneal membrane. Perit Dial Int. 2009;29 Suppl 2:S195-7 pubmed
    ..The experimental studies indicate favorable effects of combining osmotic agents, together with drugs that interfere with the polyol pathway and the formation of advanced glycosylation end-products. ..
  24. Sun Y, Zhu F, Yu X, Nie J, Huang F, Li X, et al. Treatment of established peritoneal fibrosis by gene transfer of Smad7 in a rat model of peritoneal dialysis. Am J Nephrol. 2009;30:84-94 pubmed publisher
    ..gene transfer significantly attenuated the increased peritoneal fibrosis including the thickening of fibrotic peritoneum, accumulation of alpha-SMA and collagen I, and an improvement in peritoneal dysfunction (all p < 0.05)...
  25. Yokoyama Y, Masaki T, Kiribayashi K, Nakashima A, Kokoroishi K, Ogawa T, et al. 15-Deoxy-Delta12,14-prostaglandin J2 inhibits angiotensin II-induced fibronectin expression via hepatocyte growth factor induction in human peritoneal mesothelial cells. Ther Apher Dial. 2010;14:43-51 pubmed publisher
    ..Furthermore, PHA-665752 attenuates the inhibitory effects of 15d-PGJ(2) on FN secretion. These findings suggest that 15d-PGJ(2) has a novel and potent antifibrotic effect in HPMC and this action is likely mediated by HGF. ..
  26. Imai T, Hirahara I, Morishita Y, Onishi A, Inoue M, Muto S, et al. DNA microarray analysis of the epithelial-mesenchymal transition of mesothelial cells in a rat model of peritoneal dialysis. Adv Perit Dial. 2011;27:11-5 pubmed
    ..Mesenchymal-like cells over-proliferated on the surface of the peritoneum. A DNA microarray analysis revealed that the expression of 168 genes had increased by more than a factor of 4...
  27. Devuyst O, Margetts P, Topley N. The pathophysiology of the peritoneal membrane. J Am Soc Nephrol. 2010;21:1077-85 pubmed publisher
    ..These studies are relevant to mechanisms responsible not only for the major complications of PD but also for endothelial biology, host defense, inflammation, and tissue repair processes. ..
  28. Ni J, McLoughlin R, Brodovitch A, Moulin P, Brouckaert P, Casadei B, et al. Nitric oxide synthase isoforms play distinct roles during acute peritonitis. Nephrol Dial Transplant. 2010;25:86-96 pubmed publisher
    ..isoforms has been implicated in acute peritonitis, but the role played by the NOS isoforms expressed in the peritoneum is unknown...
  29. Fang C, Chou T, Lin G, Yen Z, Lee C, Chen S. Peritoneal infusion with cold saline decreased postoperative intra-abdominal adhesion formation. World J Surg. 2010;34:721-7 pubmed publisher
    ..Postoperative intra-abdominal adhesion is a common morbidity after laparotomy. We try to determine whether peritoneal infusion with cold saline may decrease postoperative intra-abdominal adhesion formation...
  30. Aoki S, Makino J, Nagashima A, Takezawa T, Nomoto N, Uchihashi K, et al. Fluid flow stress affects peritoneal cell kinetics: possible pathogenesis of peritoneal fibrosis. Perit Dial Int. 2011;31:466-76 pubmed publisher
    ..During PD, the dialysis solution continuously generates fluid flow stress to the peritoneum under peristalsis and body motion...
  31. Sikkink C, Reijnen M, Duffhues B, de Man B, Lomme R, van Goor H. Intercellular adhesion molecule-1 and gelatinase expression in human peritoneal mesothelial cells during propagation in culture. Transl Res. 2009;153:240-8 pubmed publisher
    ..For omental cells, a differential effect of stimulation occurs depending on whether the cells have been passaged 2 or 4 times. The presence of hyaluronan did not affect the expression of ICAM-1 or the gelatinases...
  32. Gotloib L. Mechanisms of cell death during peritoneal dialysis. A role for osmotic and oxidative stress. Contrib Nephrol. 2009;163:35-44 pubmed publisher
    ..To offer a condensed description of the modes of cell death and the involved mechanisms behind them as detected in the different layers of the peritoneal tissue during experimental and clinical, long-term peritoneal dialysis (PD)...
  33. Ayuzawa N, Ishibashi Y, Takazawa Y, Kume H, Fujita T. Peritoneal morphology after long-term peritoneal dialysis with biocompatible fluid: recent clinical practice in Japan. Perit Dial Int. 2012;32:159-67 pubmed publisher
    ..Clinical practice has been modified in Japan, especially for anuric patients, and now includes the use of hybrid therapy. The impact on peritoneal morphology has not been well reported...
  34. Schulke L, Berbic M, Manconi F, Tokushige N, Markham R, Fraser I. Dendritic cell populations in the eutopic and ectopic endometrium of women with endometriosis. Hum Reprod. 2009;24:1695-703 pubmed publisher
    ..The aim of this study was to investigate DC populations in the eutopic and ectopic endometrium of women with endometriosis compared with controls...
  35. Theegarten D, Boukercha S, Philippou S, Anhenn O. Submesothelial deposition of carbon nanoparticles after toner exposition: case report. Diagn Pathol. 2010;5:77 pubmed publisher
    ..Laparoscopy done for suspected endometriosis surprisingly revealed black spots within the peritoneum. Submesothelial aggregates of CNP with a diameter of 31-67 nm were found by scanning and transmission electron ..
  36. Roth B, Birkhäuser F, Zehnder P, Burkhard F, Thalmann G, Studer U. Readaptation of the peritoneum following extended pelvic lymphadenectomy and cystectomy has a significant beneficial impact on early postoperative recovery and complications: results of a prospective randomized trial. Eur Urol. 2011;59:204-10 pubmed publisher
    ..Prolonged postoperative pain and delayed intestinal transit are frequent problems following extended pelvic lymph-node dissection (PLND) and cystectomy...
  37. Carrión B, Perez Martinez F, Monteagudo S, Pérez Carrión M, Gomez Roldan C, Ceña V, et al. Atorvastatin reduces high glucose toxicity in rat peritoneal mesothelial cells. Perit Dial Int. 2011;31:325-31 pubmed publisher
    ..We studied the toxic effects of high glucose (50 mmol/L and 83 mmol/L) and its reversal by atorvastatin (0.5 - 5 ?mol/L) on cultures of rat peritoneal mesothelial cells (PMCs)...
  38. Horiuchi T, Matsunaga K, Banno M, Nakano Y, Nishimura K, Hanzawa C, et al. HPMCs induce greater intercellular delocalization of tight junction-associated proteins due to a higher susceptibility to H2O2 compared with HUVECs. Perit Dial Int. 2009;29:217-26 pubmed
  39. Lauder C, Garcea G, Strickland A, Maddern G. Use of a modified chitosan-dextran gel to prevent peritoneal adhesions in a rat model. J Surg Res. 2011;171:877-82 pubmed publisher
    ..This study examines the application of a modified chitosan-dextran (CD) gel to the intraperitoneal cavity to reduce adhesion formation. This is a unique synthetic gel, its active ingredients being succinyl chitosan and dextran aldehyde...
  40. Lauder C, Garcea G, Strickland A, Maddern G. Abdominal adhesion prevention: still a sticky subject?. Dig Surg. 2010;27:347-58 pubmed publisher
    ..There is an ongoing need to evaluate current understanding of adhesion formation and products aimed at prevention. Failure to keep up to date with adhesion treatment may subject clinicians to a greater medico-legal risk...
  41. Fassbender A, Overbergh L, Verdrengh E, Kyama C, Vodolazakaia A, Bokor A, et al. How can macroscopically normal peritoneum contribute to the pathogenesis of endometriosis?. Fertil Steril. 2011;96:697-9 pubmed publisher
    This study indicates that the immunobiology of macroscopically normal peritoneum is relevant to understand the pathogenesis of endometriosis...
  42. Cabourne E, Roberts G, Goldin R, Ryder T, Mobberly M, Ziprin P. Investigation of tumor-peritoneal interactions in the pathogenesis of peritoneal metastases using a novel ex vivo peritoneal model. J Surg Res. 2010;164:e265-72 pubmed publisher
    ..The aim of this experimental study is to develop and validate a novel ex vivo model of the human peritoneum to better identify factors involved in the development of peritoneal metastasis in order to improve its ..
  43. Bates G, Shomento S. Adhesion prevention in patients with multiple cesarean deliveries. Am J Obstet Gynecol. 2011;205:S19-24 pubmed publisher
    ..This article discusses what is currently known about adhesion prevention in the obstetric population and highlights the paucity of level I evidence available to clinicians in this setting...
  44. Mizuno M, Ito Y, Mizuno T, Harris C, Suzuki Y, Okada N, et al. Membrane complement regulators protect against fibrin exudation increases in a severe peritoneal inflammation model in rats. Am J Physiol Renal Physiol. 2012;302:F1245-51 pubmed publisher
    ..peritonitis developed when zymosan was administered intraperitoneally following scraping injury of rat peritoneum (Mizuno M, Ito Y, Hepburn N, Mizuno T, Noda Y, Yuzawa Y, Harris CL, Morgan BP, Matsuo S...
  45. Ksiazek K, Mikula Pietrasik J, Korybalska K, Dworacki G, Jorres A, Witowski J. Senescent peritoneal mesothelial cells promote ovarian cancer cell adhesion: the role of oxidative stress-induced fibronectin. Am J Pathol. 2009;174:1230-40 pubmed publisher
    ..These data indicate that oxidative stress that accompanies senescence may increase FN production by HOMCs and thus facilitate binding and dissemination of ovarian cancer cells...
  46. Baroni G, Schuinski A, de Moraes T, Meyer F, Pecoits Filho R. Inflammation and the peritoneal membrane: causes and impact on structure and function during peritoneal dialysis. Mediators Inflamm. 2012;2012:912595 pubmed publisher
    ..An understanding of the mechanisms involved in peritoneal inflammation is fundamental to improve patient survival and provide a better quality of life...
  47. de Bree E, Helm C. Hyperthermic intraperitoneal chemotherapy in ovarian cancer: rationale and clinical data. Expert Rev Anticancer Ther. 2012;12:895-911 pubmed publisher
  48. Schreinemacher M, Emans P, Gijbels M, Greve J, Beets G, Bouvy N. Degradation of mesh coatings and intraperitoneal adhesion formation in an experimental model. Br J Surg. 2009;96:305-13 pubmed publisher
    ..In this experimental study the ability of different coated and uncoated meshes to attenuate adhesion formation was examined...
  49. Griffith J, Liu Y, Tekmal R, Binkley P, Holden A, Schenken R. Menstrual endometrial cells from women with endometriosis demonstrate increased adherence to peritoneal cells and increased expression of CD44 splice variants. Fertil Steril. 2010;93:1745-9 pubmed publisher
    ..Here, we assessed whether ESCs and EECs from women with endometriosis demonstrate increased adherence to PMCs and examined CD44 splice variants' potential role in this process...
  50. Yu M, Shin K, Kim J, Kim Y, Chung S, Park S, et al. HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium. J Am Soc Nephrol. 2009;20:567-81 pubmed publisher
    ..Treatment of HPMCs with HGF or BMP-7 blocks high glucose-induced EMT, and BMP-7 ameliorates peritoneal fibrosis in an animal model of peritoneal dialysis...
  51. Berbic M, Hey Cunningham A, Ng C, Tokushige N, Ganewatta S, Markham R, et al. The role of Foxp3+ regulatory T-cells in endometriosis: a potential controlling mechanism for a complex, chronic immunological condition. Hum Reprod. 2010;25:900-7 pubmed publisher
    ..Surprisingly, Foxp3+ regulatory T-cells, which control and suppress a range of immune responses, have not previously been investigated in endometriosis...
  52. Lambie M, John B, Mushahar L, Huckvale C, Davies S. The peritoneal osmotic conductance is low well before the diagnosis of encapsulating peritoneal sclerosis is made. Kidney Int. 2010;78:611-8 pubmed publisher
    ..Thus, our study shows that regular peritoneal membrane function tests can identify most patients at high risk of developing EPS before its occurrence...
  53. Lee B, Kim K, Soh K. Visualizing the network of Bonghan ducts in the omentum and peritoneum by using Trypan blue. J Acupunct Meridian Stud. 2009;2:66-70 pubmed publisher
    ..By using it, we observed a weblike network of BHDs which was in various membrane structures, such as the peritoneum, and omenta...
  54. Ksiazek K, Mikuła Pietrasik J, Catar R, Dworacki G, Winckiewicz M, Frydrychowicz M, et al. Oxidative stress-dependent increase in ICAM-1 expression promotes adhesion of colorectal and pancreatic cancers to the senescent peritoneal mesothelium. Int J Cancer. 2010;127:293-303 pubmed publisher
    ..These results indicate that increased oxidative stress and increased expression of ICAM-1 in senescent HOMCs may facilitate peritoneal adhesion of selected colorectal and pancreatic cancers...
  55. McGee S, Routh J, Pereira C, Gettman M. Minimal contamination of the human peritoneum after transvesical incision. J Endourol. 2009;23:659-63 pubmed publisher
    ..Our study examines the resultant microbial contamination of the human peritoneum after transvesical incision and exposure of the abdomen to bladder contents during robot-assisted laparoscopic ..
  56. Zappa M, Sibert A, Vullierme M, Bertin C, Bruno O, Vilgrain V. [Postoperative imaging of the peritoneum and abdominal wall]. J Radiol. 2009;90:969-79 pubmed
    ..Other rare complications include desmoid tumors and gossypiboma. Wall complications, after laparotomy as well as laparoscopic surgery, are mainly hematoma, infections and wound hernia...
  57. Gangji A, Brimble K, Margetts P. Association between markers of inflammation, fibrosis and hypervolemia in peritoneal dialysis patients. Blood Purif. 2009;28:354-8 pubmed publisher
    ..The link between inflammation and hypervolemia has not been extensively studied. The aim of this study was to determine if an association exists between hypervolemia and markers of inflammation in PD patients...
  58. Whang S, Astudillo J, Sporn E, Bachman S, Miedema B, Davis W, et al. In search of the best peritoneal adhesion model: comparison of different techniques in a rat model. J Surg Res. 2011;167:245-50 pubmed publisher
    ..The aim of this study was to compare quality and quantity of adhesions in four different models and to find the best model...
  59. Chaudhary K, Khanna R. Biocompatible peritoneal dialysis solutions: do we have one?. Clin J Am Soc Nephrol. 2010;5:723-32 pubmed publisher
    ..This review discusses the current status of these biocompatible solutions in PD patients...
  60. Oh K, Jung J, Yoon M, Song A, Lee H, Ro H, et al. Intra-peritoneal interleukin-6 system is a potent determinant of the baseline peritoneal solute transport in incident peritoneal dialysis patients. Nephrol Dial Transplant. 2010;25:1639-46 pubmed publisher
    ..We also hypothesized that the dialysate concentrations of IL-6/sIL-6R could be closely related to local inflammation or angiogenesis in the peritoneal cavity...
  61. Yokoi H, Kasahara M, Mori K, Ogawa Y, Kuwabara T, Imamaki H, et al. Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis. Kidney Int. 2012;81:160-9 pubmed publisher
    ..To study this, we used microarray analysis and compared gene expression profiles of the peritoneum in control and chlorhexidine gluconate (CG)-induced peritoneal fibrosis mice...
  62. da Luz M, Barral S, Barral C, Bechara C, Lacerda Filho A. Idiopathic encapsulating peritonitis: report of two cases. Surg Today. 2011;41:1644-8 pubmed publisher
    ..The prognosis after appropriate surgical therapy is good, but depends on coexisting diseases...
  63. Cho J, Hur I, Kim C, Park S, Ryu H, Yook J, et al. Impact of systemic and local peritoneal inflammation on peritoneal solute transport rate in new peritoneal dialysis patients: a 1-year prospective study. Nephrol Dial Transplant. 2010;25:1964-73 pubmed publisher
    ..The association between peritoneal solute transport rates (PSTRs) and inflammatory markers in patients on peritoneal dialysis (PD) is still under investigation. We aimed to elucidate their relationship during the first year on PD...
  64. Johnson D, Hawley C, McDonald S, Brown F, Rosman J, Wiggins K, et al. Superior survival of high transporters treated with automated versus continuous ambulatory peritoneal dialysis. Nephrol Dial Transplant. 2010;25:1973-9 pubmed publisher
  65. Schug Pass C, Lippert H, Kockerling F. Fixation of mesh to the peritoneum using a fibrin glue: investigations with a biomechanical model and an experimental laparoscopic porcine model. Surg Endosc. 2009;23:2809-15 pubmed publisher
    ..The experiments in this study were aimed at elucidating the extent to which tack- or suture-based permanent fixation can be replaced by fixation with fibrin glue for laparoscopic intraperitoneal repair of abdominal wall hernias...
  66. Nishii T, Yashiro M, Shinto O, Sawada T, Ohira M, Hirakawa K. Cancer stem cell-like SP cells have a high adhesion ability to the peritoneum in gastric carcinoma. Cancer Sci. 2009;100:1397-402 pubmed publisher
    ..Oct3/4 and Sox2 may be associated with CSC in gastric cancer...
  67. Patel P, Sekiguchi Y, Oh K, Patterson S, Kolb M, Margetts P. Smad3-dependent and -independent pathways are involved in peritoneal membrane injury. Kidney Int. 2010;77:319-28 pubmed publisher
    ..cells to a mesenchymal phenotype plays an integral role in the angiogenic and fibrotic changes seen in the peritoneum of patients receiving long-term peritoneal dialysis...
  68. Sekiguchi Y, Hamada C, Ro Y, Nakamoto H, Inaba M, Shimaoka T, et al. Differentiation of bone marrow-derived cells into regenerated mesothelial cells in peritoneal remodeling using a peritoneal fibrosis mouse model. J Artif Organs. 2012;15:272-82 pubmed publisher
    Marked thickening of the peritoneum and vasculopathy in the submesothelial compact zone have been reported in long-term peritoneal dialysis patients...
  69. Vlijm A, Stoker J, Bipat S, Spijkerboer A, Phoa S, Maes R, et al. Computed tomographic findings characteristic for encapsulating peritoneal sclerosis: a case-control study. Perit Dial Int. 2009;29:517-22 pubmed
    ..To establish CT findings characteristic for EPS, we compared CT findings between EPS patients and long-term peritoneal dialysis (PD) patients without EPS...
  70. Gotloib L. The mesothelium under the siege of dialysis solutions: old glucose, new glucose, and glucose-free osmotic agents. Adv Perit Dial. 2009;25:6-10 pubmed
    ..Icodextrin does not appear to be more biocompatible than glucose. Amino-acid-based solution is less harmful to the mesothelium, but its usefulness is still limited...
  71. Merino M, Montes C, Acosta Rodriguez E, Bermejo D, Amezcua Vesely M, Gruppi A. Peritoneum from Trypanosoma cruzi-infected mice is a homing site of Syndecan-1 neg plasma cells which mainly provide non-parasite-specific antibodies. Int Immunol. 2010;22:399-410 pubmed publisher
    ..Electron microscopy studies showed that peritoneum of infected mice lodges plasma cells with typical morphology as well as atypical plasma cells named 'Mott-like ..
  72. Loureiro J, Aguilera A, Selgas R, Sandoval P, Albar Vizcaino P, Perez Lozano M, et al. Blocking TGF-?1 protects the peritoneal membrane from dialysate-induced damage. J Am Soc Nephrol. 2011;22:1682-95 pubmed publisher
    ..Exposure of the peritoneum to PD fluid induced fibrosis, angiogenesis, functional impairment, and the accumulation of fibroblasts...
  73. Lee H, Hwang Y, Jung J, Na K, Kim H, Son M, et al. Comparison of vascular calcification scoring systems using plain radiographs to predict vascular stiffness in peritoneal dialysis patients. Nephrology (Carlton). 2011;16:656-62 pubmed publisher
    ..The objective of this study is to compare predictability of two different vascular calcification scoring systems using plain radiographs in peritoneal dialysis (PD) patients...
  74. Takahashi S, Taniguchi Y, Nakashima A, Arakawa T, Kawai T, Doi S, et al. Mizoribine suppresses the progression of experimental peritoneal fibrosis in a rat model. Nephron Exp Nephrol. 2009;112:e59-69 pubmed publisher
    ..We therefore examined the effects of mizoribine in an experimental model of peritoneal fibrosis...
  75. Braun N, Fritz P, Biegger D, Kimmel M, Reimold F, Ulmer C, et al. Difference in the expression of hormone receptors and fibrotic markers in the human peritoneum--implications for therapeutic targets to prevent encapsulating peritoneal sclerosis. Perit Dial Int. 2011;31:291-300 pubmed publisher
    ..of nuclear receptors [progesterone (PR), androgen (AR), vitamin D (VDR), and glucocorticoid (GCR)] in the human peritoneum. We also investigated estrogen receptor (ER), matrix metalloproteinase 9 (MMP9), and transforming growth factor ?..
  76. Saito Y, Sekine W, Sano R, Komatsu S, Mizuno H, Katabami K, et al. Potentiation of cell invasion and matrix metalloproteinase production by alpha3beta1 integrin-mediated adhesion of gastric carcinoma cells to laminin-5. Clin Exp Metastasis. 2010;27:197-205 pubmed publisher
    We previously reported that the adhesion of gastric carcinoma cells to the peritoneum mediated by the alpha3beta1 integrin-laminin interaction is a key step in the initial process of peritoneal metastatic dissemination...
  77. Adamidis K, Zachariou C, Kopaka M, Charitaki E, Drakopoulos V, Kara P, et al. Sclerosing peritonitis presenting 2 years after renal transplantation in a former CAPD patient. Ren Fail. 2011;33:246-8 pubmed publisher
    ..Although the appearance of SP after renal transplantation is extremely rare, it must be included in the differential diagnosis of every case of unexplained malnutrition and abdominal obstruction in a patient with a PD history...
  78. Zhang T, Ma Z, Wang R, Wang Y, Wang S, Cheng Z, et al. Thrombin facilitates invasion of ovarian cancer along peritoneum by inducing monocyte differentiation toward tumor-associated macrophage-like cells. Cancer Immunol Immunother. 2010;59:1097-108 pubmed publisher
    ..The inflammatory environment of the peritoneum in EOC contains abundant macrophages, activated thrombin, and thrombin-associated receptors...
  79. Agresta F, Mazzarolo G, Bedin N. Incarcerated internal hernia of the small intestine through a re-approximated peritoneum after a trans-abdominal pre-peritoneal procedure--apropos of two cases: review of the literature. Hernia. 2011;15:347-50 pubmed publisher
  80. Poli Neto O, Filho A, Rosa e Silva J, Barbosa H, Candido dos Reis F, Nogueira A. Increased capsaicin receptor TRPV1 in the peritoneum of women with chronic pelvic pain. Clin J Pain. 2009;25:218-22 pubmed publisher
    To investigate the expression of capsaicin receptor [transient receptor potential vanilloid type-1 (TRPV1)] in the peritoneum of women with chronic pelvic pain (CPP).
  81. Balafa O, Halbesma N, Struijk D, Dekker F, Krediet R. Peritoneal albumin and protein losses do not predict outcome in peritoneal dialysis patients. Clin J Am Soc Nephrol. 2011;6:561-6 pubmed publisher
    ..The aim of this study was to investigate whether baseline peritoneal loss and clearance of albumin and other proteins is a risk factor of death in peritoneal dialysis patients...
  82. Aysan E, Bektas H, Kaygusuz A, Huq G. A new approach for decreasing postoperative peritoneal adhesions: preventing peritoneal trauma with soybean oil. J Invest Surg. 2009;22:275-80 pubmed
    ..Covering peritoneal surfaces with soybean oil may decrease peritoneal adhesions by preventing peritoneal trauma...
  83. Sandoval P, Loureiro J, Gonzalez Mateo G, Pérez Lozano M, Maldonado Rodríguez A, Sanchez Tomero J, et al. PPAR-? agonist rosiglitazone protects peritoneal membrane from dialysis fluid-induced damage. Lab Invest. 2010;90:1517-32 pubmed publisher
    ..Exposure of the peritoneum to PD fluid resulted in AGEs accumulation, an inflammatory response, the loss of mesothelial cell monolayer and ..
  84. Körbel C, Menger M, Laschke M. Size and spatial orientation of uterine tissue transplants on the peritoneum crucially determine the growth and cyst formation of endometriosis-like lesions in mice. Hum Reprod. 2010;25:2551-8 pubmed publisher
    ..However, until now the surgical techniques have not been standardized, and we address this issue here...
  85. Colmont C, Raby A, Dioszeghy V, LeBouder E, Foster T, Jones S, et al. Human peritoneal mesothelial cells respond to bacterial ligands through a specific subset of Toll-like receptors. Nephrol Dial Transplant. 2011;26:4079-90 pubmed publisher
    ..To investigate the initiation of bacterial peritonitis, we characterized TLR activation by bacterial ligands in human peritoneal mesothelial cells (HPMC)...
  86. Bellón T, Martinez V, Lucendo B, del Peso G, Castro M, Aroeira L, et al. Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis. Nephrol Dial Transplant. 2011;26:2995-3005 pubmed publisher