skull base

Summary

Summary: The inferior region of the skull consisting of an internal (cerebral), and an external (basilar) surface.

Top Publications

  1. Hornyak M, Digre K, Couldwell W. Neuro-ophthalmologic manifestations of benign anterior skull base lesions. Postgrad Med. 2009;121:103-14 pubmed publisher
    Visual disturbance is a common presenting symptom of anterior skull base lesions. These lesions cause deterioration in visual acuity, restriction of the visual field, or reduction of ocular mobility...
  2. Combs S, Sterzing F, Uhl M, Habl G, Schubert K, Debus J, et al. Helical tomotherapy for meningiomas of the skull base and in paraspinal regions with complex anatomy and/or multiple lesions. Tumori. 2011;97:484-91 pubmed publisher
    ..To evaluate helical tomotherapy for the treatment of complex-shaped uni- or multifocal meningiomas...
  3. Zanoletti E, Martini A, Emanuelli E, Mazzoni A. Lateral approaches to the skull base. Acta Otorhinolaryngol Ital. 2012;32:281-7 pubmed
    Progress in the study of skull base anatomy and the different lesions involving it has led to more and more precise knowledge of the site...
  4. Harvey R, Parmar P, Sacks R, Zanation A. Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence. Laryngoscope. 2012;122:452-9 pubmed publisher
    Systematically review the outcomes of endoscopic endonasal techniques to reconstruct large skull base defects (ESBR)...
  5. Manes R, Barnett S, Batra P. Utility of novel 3-dimensional stereoscopic vision system for endoscopic sinonasal and skull-base surgery. Int Forum Allergy Rhinol. 2011;1:191-7 pubmed publisher
    The objective of this pilot study was to evaluate the utility of novel 3-dimensional (3D) endoscopy during endoscopic sinonasal and skull base surgery.
  6. Eloy J, Choudhry O, Friedel M, Kuperan A, Liu J. Endoscopic nasoseptal flap repair of skull base defects: is addition of a dural sealant necessary?. Otolaryngol Head Neck Surg. 2012;147:161-6 pubmed publisher
    We compared the incidence of postoperative cerebrospinal fluid (CSF) leaks in patients undergoing endoscopic skull base repair with a pedicled nasoseptal flap (PNSF) with or without the addition of a dural sealant.
  7. Eloy J, Kuperan A, Choudhry O, Harirchian S, Liu J. Efficacy of the pedicled nasoseptal flap without cerebrospinal fluid (CSF) diversion for repair of skull base defects: incidence of postoperative CSF leaks. Int Forum Allergy Rhinol. 2012;2:397-401 pubmed publisher
    The advances in endoscopic skull base surgery have led to the resection of increasingly larger cranial base lesions and the creation of larger skull base defects with the potential for increased postoperative high-flow cerebrospinal fluid ..
  8. Wei X, Li W, Li M, Li Y, Wang D, Zhang Y, et al. Detection of brain lesions at the skull base using diffusion-weighted imaging with readout-segmented echo-planar imaging and generalized autocalibrating partially parallel acquisitions. Neurol India. 2011;59:839-43 pubmed publisher
    To analyze the value of readout-segmented echo-planar imaging (rs-EPI) with parallel imaging and a two-dimensional (2D) navigator-based reacquisition technique in the detection of brain lesions at the skull base.
  9. Liang F, Sun W, Han P, Lu X, Lian Y, Huang X. Detecting plasma Epstein-Barr virus DNA to diagnose postradiation nasopharyngeal skull base lesions in nasopharyngeal carcinoma patients: a prospective study. Chin J Cancer. 2012;31:142-9 pubmed publisher
    The diagnosis of postradiation nasopharyngeal skull base lesions in petients with nasopharyngeal carcinoma (NPC) is still a tough problem in clinical practice. An early and accurate diagnosis is important for subsequent management...

More Information

Publications88

  1. Scheller C, Vogel A, Simmermacher S, Rachinger J, Prell J, Strauss C, et al. Prophylactic intravenous nimodipine treatment in skull base surgery: pharmacokinetic aspects. J Neurol Surg A Cent Eur Neurosurg. 2012;73:153-9 pubmed publisher
    ..Nimodipine is primarily used in subarachnoid hemorrhage (SAH). Clinical trials revealed also a beneficial effect of prophylactic nimodipine treatment on cranial nerve functions following vestibular schwannoma surgery...
  2. Dallan I, Castelnuovo P, Vicini C, Tschabitscher M. The natural evolution of endoscopic approaches in skull base surgery: robotic-assisted surgery?. Acta Otorhinolaryngol Ital. 2011;31:390-4 pubmed
    ..This is particularly intriguing in skull base regions...
  3. Oostra A, van Furth W, Georgalas C. Extended endoscopic endonasal skull base surgery: from the sella to the anterior and posterior cranial fossa. ANZ J Surg. 2012;82:122-30 pubmed publisher
    b>Skull base surgery has gone through significant changes with the development of extended endoscopic endonasal approaches over the last decade...
  4. Burkhardt J, Neidert M, Grotzer M, Krayenbuhl N, Bozinov O. Surgical resection of pediatric skull base meningiomas. Childs Nerv Syst. 2013;29:83-7 pubmed publisher
    Meningiomas in children are rare, especially those located at the skull base. In this study, we report our experience of meningioma surgery in the pediatric population and compare our findings of skull base (SB) versus non-skull base (NSB)..
  5. Liu J, Schmidt R, Choudhry O, Shukla P, Eloy J. Surgical nuances for nasoseptal flap reconstruction of cranial base defects with high-flow cerebrospinal fluid leaks after endoscopic skull base surgery. Neurosurg Focus. 2012;32:E7 pubmed publisher
    ..endonasal approaches have allowed for a minimally invasive solution for removal of a variety of ventral skull base lesions, including intradural tumors...
  6. Han J, Zhang Q, Kong F, Gao Y. The incidence of invasion and metastasis of nasopharyngeal carcinoma at different anatomic sites in the skull base. Anat Rec (Hoboken). 2012;295:1252-9 pubmed publisher
    ..incidence of direct invasion and metastasis of nasopharyngeal carcinoma (NPC) at different anatomic sites in the skull base using magnetic resonance imaging (MRI)...
  7. Lee D, Yoon T, Lee J, Joo Y, Kim I, Jang W, et al. Clinical utility of the inferior turbinate flaps in the reconstruction of the nasal septum and skull base. J Craniofac Surg. 2012;23:e322-6 pubmed publisher
    ..been used for the repair of the septal perforation, and the PPITF has been used for the reconstruction of the skull base. Because of the technical difficulties of endoscopic preparation of the ITF, clinical studies on endoscopic ..
  8. Eloy J, Kalyoussef E, Choudhry O, Baredes S, Gandhi C, Govindaraj S, et al. Salvage endoscopic nasoseptal flap repair of persistent cerebrospinal fluid leak after open skull base surgery. Am J Otolaryngol. 2012;33:735-40 pubmed publisher
    Persistent cerebrospinal fluid (CSF) rhinorrhea after open skull base surgery can be challenging to manage due to the risk of meningitis, brain abscess, surgical morbidity associated with revision craniotomy, and the lack of available ..
  9. Gil Z, Margalit N. Anteriorly based inferior turbinate flap for endoscopic skull base reconstruction. Otolaryngol Head Neck Surg. 2012;146:842-7 pubmed publisher
    In the absence of the nasal septal flap, there is limited ability to reconstruct the anterior skull base because of the paucity of alternative intranasal vascularized flaps...
  10. de Almeida J, Witterick I, Gullane P, Gentili F, Lohfeld L, Ringash J, et al. Quality of life instruments for skull base pathology: systematic review and methodologic appraisal. Head Neck. 2013;35:1221-31 pubmed publisher
    Several quality of life (QOL) instruments exist for skull base pathology, however, there have been no attempts to appraise and systematically review these instruments.
  11. Hong W, Tsai J, Chang S, Sorger J. Robotic skull base surgery via supraorbital keyhole approach: a cadaveric study. Neurosurgery. 2013;72 Suppl 1:33-8 pubmed publisher
    The supraorbital keyhole approach has been used in anterior skull base tumor and aneurysm surgery. However, there are debates regarding the safety and limitations of this kind of approach.
  12. Maione L, Benadjaoud S, Eloit C, Sinisi A, Colao A, Chanson P, et al. Computed tomography of the anterior skull base in Kallmann syndrome reveals specific ethmoid bone abnormalities associated with olfactory bulb defects. J Clin Endocrinol Metab. 2013;98:E537-46 pubmed publisher
    ..Kallmann syndrome (KS) is characterized by congenital hypogonadotropic hypogonadism (CHH) and an impaired sense of smell related to defective development of the olfactory system...
  13. Lyson T, Sieskiewicz A, Rutkowski R, Kochanowicz J, Turek G, Rogowski M, et al. [Transnasal endoscopic approaches to the cranial base]. Neurol Neurochir Pol. 2013;47:63-73 pubmed
    ..The authors of this contribution use most of these approaches in their endoscopic skull base surgery...
  14. Roth J, Singh A, Nyquist G, Fraser J, Bernardo A, Anand V, et al. Three-dimensional and 2-dimensional endoscopic exposure of midline cranial base targets using expanded endonasal and transcranial approaches. Neurosurgery. 2009;65:1116-28; discussion 1128-30 pubmed publisher
    ..Three-dimensional endoscopes augment the spatial orientation and may improve patient safety and the learning curve for endoscopic approaches to the midline cranial base. ..
  15. Garcia Navarro V, Anand V, Schwartz T. Gasket seal closure for extended endonasal endoscopic skull base surgery: efficacy in a large case series. World Neurosurg. 2013;80:563-8 pubmed publisher
    ..To assess long-term efficacy of the gasket seal, a method for watertight closure of the cranial base using autologous fascia lata held in place by a rigid buttress, in a large case series...
  16. Connor S, Flis C. The contribution of high-resolution multiplanar reformats of the skull base to the detection of skull-base fractures. Clin Radiol. 2005;60:878-85 pubmed
    ..To investigate the contribution of routine review of submillimetric multiplanar reformats to the diagnosis of skull-base fractures...
  17. Waterval J, Stokroos R, Bauer N, de Bondt R, Manni J. Phenotypic manifestations and management of hyperostosis cranialis interna, a hereditary bone dysplasia affecting the calvaria and the skull base. Am J Med Genet A. 2010;152A:547-55 pubmed publisher
    ..bone disorder that is characterized by endosteal hyperostosis and osteosclerosis of the calvaria and the skull base (OMIM 144755)...
  18. Zanation A, Carrau R, Snyderman C, Germanwala A, Gardner P, Prevedello D, et al. Nasoseptal flap reconstruction of high flow intraoperative cerebral spinal fluid leaks during endoscopic skull base surgery. Am J Rhinol Allergy. 2009;23:518-21 pubmed publisher
    ..The nasoseptal flap is an excellent anterior skull base reconstructive technique...
  19. Briggs R, Wormald P. Endoscopic transnasal intradural repair of anterior skull base cerebrospinal fluid fistulae. J Clin Neurosci. 2004;11:597-9 pubmed
    This study presents the techniques and results of endoscopic diagnosis and repair of cerebrospinal fluid (CSF) fistulae involving the anterior skull base and paranasal sinuses.
  20. Koerbel A, Gharabaghi A, Samii A, Gerganov V, von Gösseln H, Tatagiba M, et al. Trigeminocardiac reflex during skull base surgery: mechanism and management. Acta Neurochir (Wien). 2005;147:727-32; discussion 732-3 pubmed
    ..and management of the trigeminocardiac reflex (TCR) during neurosurgical procedures for lesions of the skull base. Two hundred patients underwent neurosurgical procedures for various skull base lesions and were evaluated ..
  21. Theron S, Steyn F. Clinical image. An unusual cause of proptosis: aneurysmal bone cyst of the anterior skull base. Pediatr Radiol. 2006;36:997 pubmed
  22. Huisman T, Brehmer U, Zeilinger G, Stallmach T, Gysin C. Parapharyngeal neuroglial heterotopia extending through the skull base in a neonate with airway obstruction. J Pediatr Surg. 2007;42:1764-7 pubmed
    ..Preoperative identification of intracranial extension is essential for planning surgery to prevent postoperative cerebrospinal fluid leaks or possible meningitis. ..
  23. Onodera S, Aoyama H, Katoh N, Taguchi H, Yasuda K, Yoshida D, et al. Long-term outcomes of fractionated stereotactic radiotherapy for intracranial skull base benign meningiomas in single institution. Jpn J Clin Oncol. 2011;41:462-8 pubmed publisher
    ..the outcome of linac-based fractionated stereotactic radiotherapy over the last 10 years for intracranial skull base benign meningiomas in patients who were inoperable, who had residual tumors with some components of high mitotic ..
  24. Harvey R, Sheahan P, Schlosser R. Inferior turbinate pedicle flap for endoscopic skull base defect repair. Am J Rhinol Allergy. 2009;23:522-6 pubmed publisher
    Endoscopic skull base reconstruction (ESBR) is an important advance in the management of skull base defects...
  25. Nyquist G, Anand V, Singh A, Schwartz T. Janus flap: bilateral nasoseptal flaps for anterior skull base reconstruction. Otolaryngol Head Neck Surg. 2010;142:327-31 pubmed publisher
    Large dural defects after extended endoscopic endonasal skull base resections require meticulous reconstruction to prevent a cerebrospinal fluid leak postoperatively...
  26. Chen H, Lin C, Jen Y, Juan C, Hsueh C, Lee J, et al. Ruptured internal carotid pseudoaneurysm in a nasopharyngeal carcinoma patient with skull base osteoradionecrosis. Otolaryngol Head Neck Surg. 2004;130:388-90 pubmed
  27. Kassam A, Snyderman C, Mintz A, Gardner P, Carrau R. Expanded endonasal approach: the rostrocaudal axis. Part I. Crista galli to the sella turcica. Neurosurg Focus. 2005;19:E3 pubmed
    ..More recently, the standard endonasal approach has been expanded to provide access to other, parasellar lesions. With the addition of the endoscope, this expansion carries significant potential for the resection of skull base lesions.
  28. Kong D, Kim H, Kim S, Min J, Nam D, Park K, et al. Challenging reconstructive techniques for skull base defect following endoscopic endonasal approaches. Acta Neurochir (Wien). 2011;153:807-13 pubmed publisher
    We assessed the outcomes of various reconstructive methods for skull base defect after endoscopic endonasal approaches (EEA) depending on the degree of intraoperative cerebrospinal fluid (CSF) leaks. Between Jan. 2008 and Sep...
  29. Prevedello D, Kassam A, Snyderman C, Carrau R, Mintz A, Thomas A, et al. Endoscopic cranial base surgery: ready for prime time?. Clin Neurosurg. 2007;54:48-57 pubmed
  30. Kono Y, Prevedello D, Snyderman C, Gardner P, Kassam A, Carrau R, et al. One thousand endoscopic skull base surgical procedures demystifying the infection potential: incidence and description of postoperative meningitis and brain abscesses. Infect Control Hosp Epidemiol. 2011;32:77-83 pubmed publisher
    Endonasal endoscopic skull base surgery (ESBS) is perceived as having a high risk of infection because it is performed through the sinuses, which are not sterile...
  31. Katsuno M, Yokota H, Yamamoto Y, Teramoto A. Bilateral traumatic abducens nerve palsy associated with skull base fracture--case report. Neurol Med Chir (Tokyo). 2007;47:307-9 pubmed
    A 29-year-old man presented with skull base fractures involving the bilateral petrous bones and clivus to the posterior clinoid process manifesting as bilateral abducens nerves palsy...
  32. Nyquist G, Anand V, Mehra S, Kacker A, Schwartz T. Endoscopic endonasal repair of anterior skull base non-traumatic cerebrospinal fluid leaks, meningoceles, and encephaloceles. J Neurosurg. 2010;113:961-6 pubmed publisher
    ..endonasal approach has become the preferred technique for CSF leak and encephalocele repair of the anterior skull base. The purpose of this study is to identify patient characteristics; review adjunctive perioperative treatments, ..
  33. Meng Q, Yang Y, Zhou M, Li X. Trigemino-cardiac reflex: the trigeminal depressor responses during skull base surgery. Clin Neurol Neurosurg. 2008;110:662-6 pubmed publisher
    ..reflex (TCR) defined as the phenomenon of abrupt drops in heart rate (HR) and blood pressure during skull base surgery...
  34. Sreepada G, Kwartler J. Skull base osteomyelitis secondary to malignant otitis externa. Curr Opin Otolaryngol Head Neck Surg. 2003;11:316-23 pubmed
    b>Skull base osteomyelitis secondary to malignant otitis externa was first described in 1959. Since then, advances have been made in the diagnosis, treatment, and clinical outcomes of this condition.
  35. Georgalas C, Goudakos J, Fokkens W. Osteoma of the skull base and sinuses. Otolaryngol Clin North Am. 2011;44:875-90, vii pubmed publisher
    ..We believe that the vast majority of frontal sinus osteomata can be managed endoscopically, and that only significant anterior or extreme infero-lateral extension constitute major limiting factors. ..
  36. Verillaud B, Genty E, Leboulanger N, Zerah M, Garabedian E, Roger G. Mucocele after transnasal endoscopic repair of traumatic anterior skull base fistula in children. Int J Pediatr Otorhinolaryngol. 2011;75:1137-42 pubmed publisher
    To report the long-term sinonasal complications after endoscopic repair of anterior skull base fractures in children. This study describes mucocele formation in 6 patients treated endoscopically for posttraumatic CSF fistulae...
  37. Al Kaissi A, Ben Chehida F, Ben Ghachem M, Klaushofer K, Grill F. Diffuse skull base/cervical fusion syndromes in two siblings with spondylocostal dysostosis syndrome: analysis via three dimensional computed tomography scanning. Spine (Phila Pa 1976). 2008;33:E425-8 pubmed publisher
    A study on a pair of male sibs to reach for the etiological understanding of unusual skull base/spine maldevelopment.
  38. Hadad G, Bassagasteguy L, Carrau R, Mataza J, Kassam A, Snyderman C, et al. A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap. Laryngoscope. 2006;116:1882-6 pubmed
    In patients with large dural defects of the anterior and ventral skull base after endonasal skull base surgery, there is a significant risk of a postoperative cerebrospinal fluid leak after reconstruction...
  39. Cernea C, Ferraz A, de Castro I, Sotto M, Logullo A, Bacchi C, et al. Angiogenesis and skin carcinomas with skull base invasion: a case-control study. Head Neck. 2004;26:396-400 pubmed
    ..In this study, the expression of CD34 in basal cell carcinomas ( BCCs) and squamous cell carcinomas (SCCs) with skull base invasion was compared with that in tumors with good outcome.
  40. Abuzayed B, Tanriover N, Gazioglu N, Sanus G, Ozlen F, Biceroglu H, et al. Endoscopic endonasal anatomy and approaches to the anterior skull base: a neurosurgeon's viewpoint. J Craniofac Surg. 2010;21:529-37 pubmed publisher
    The objective of this study was to review the endoscopic anatomy of the anterior skull base, defining the pitfalls of endoscopic endonasal approaches to this region...
  41. Ausman J. A revolution in skull base surgery: the quality of life matters!. Surg Neurol. 2006;65:635-6 pubmed
  42. Doglietto F, Prevedello D, Jane J, Han J, Laws E. Brief history of endoscopic transsphenoidal surgery--from Philipp Bozzini to the First World Congress of Endoscopic Skull Base Surgery. Neurosurg Focus. 2005;19:E3 pubmed
    ..led to the development of novel surgical procedures for the treatment of various pathological conditions in the skull base. In this paper the authors review the history of the endoscope--its technical development and its application--..
  43. Schaller B, Filis A, Merten H, Buchfelder M. Premature craniosynostosis--the role of skull base surgery in its correction. A surgical and radiological experience of 172 operated infants/children. J Craniomaxillofac Surg. 2012;40:195-200 pubmed publisher
    ..Functional impairment is caused either by a pathological growth pattern or increased intracranial pressure. The indications for surgery are to increase intracranial volume and to correct aesthetics...
  44. Dong C, Macdonald D, Akagami R, Westerberg B, Alkhani A, Kanaan I, et al. Intraoperative facial motor evoked potential monitoring with transcranial electrical stimulation during skull base surgery. Clin Neurophysiol. 2005;116:588-96 pubmed
  45. Gil Z, Constantini S, Spektor S, Abergel A, Khafif A, Beni Adani L, et al. Skull base approaches in the pediatric population. Head Neck. 2005;27:682-9 pubmed
    This study aimed to examine the surgical, oncologic, and developmental results of infants and children undergoing extirpation of skull base tumors.
  46. Hayashi N, Kubo M, Tsuboi Y, Nishimura S, Nishijima M, Ahmed Abdel Aal M, et al. Impact of anomalous origin of the ophthalmic artery from the middle meningeal artery on selection of surgical approach to skull base meningioma. Surg Neurol. 2007;68:568-71; discussion 571-2 pubmed
    ..Ectopic sites of origin of the ophthalmic artery from the MMA are associated with visual complications of surgery directed along the sphenoidal wing or embolization of the MMA...
  47. Pirris S, Pollack I, Snyderman C, Carrau R, Spiro R, Tyler Kabara E, et al. Corridor surgery: the current paradigm for skull base surgery. Childs Nerv Syst. 2007;23:377-84 pubmed
    ..In this report, we present the case of a 3-year-old boy who was found to have a large posterior pharyngeal, clival, and posterior fossa tumor detected on a CT scan after a closed head injury...
  48. Schuknecht B, Simmen D, Briner H, Holzmann D. Nontraumatic skull base defects with spontaneous CSF rhinorrhea and arachnoid herniation: imaging findings and correlation with endoscopic sinus surgery in 27 patients. AJNR Am J Neuroradiol. 2008;29:542-9 pubmed
    Defects at the skull base leading to spontaneous CSF rhinorrhea are rare lesions...
  49. Boseley M, Tami T. Endoscopic management of anterior skull base encephaloceles. Ann Otol Rhinol Laryngol. 2004;113:30-3 pubmed
    Encephaloceles are relatively rare phenomena produced by the protrusion of brain and dura through an anterior skull base defect. Although they can occur as congenital defects, encephaloceles can also present after trauma...
  50. Tatreau J, Patel M, Shah R, McKinney K, Wheless S, Senior B, et al. Anatomical considerations for endoscopic endonasal skull base surgery in pediatric patients. Laryngoscope. 2010;120:1730-7 pubmed publisher
    Pediatric skull base surgery is limited by several boney sinonasal landmarks that must be overcome prior to tumor dissection...
  51. Bumm K, Wurm J, Rachinger J, Dannenmann T, Bohr C, Fahlbusch R, et al. An automated robotic approach with redundant navigation for minimal invasive extended transsphenoidal skull base surgery. Minim Invasive Neurosurg. 2005;48:159-64 pubmed
    ..An image-guided robotic system was designed to address potential human errors in performing transsphenoidal sinus surgery by combining the reproducible accuracy of a robotic system with standard computer navigation...
  52. Cavallo L, Messina A, Esposito F, de Divitiis O, Dal Fabbro M, de Divitiis E, et al. Skull base reconstruction in the extended endoscopic transsphenoidal approach for suprasellar lesions. J Neurosurg. 2007;107:713-20 pubmed
    ..Effective reconstruction of large skull base defects is a major concern in such extended approaches and remains challenging.
  53. Tsao Y, Kao C, Wang H, Chin S, Moe K. Transorbital penetrating injury of paranasal sinuses and anterior skull base by a plastic chair glide: management options of a foreign body in multiple anatomic compartments. Otolaryngol Head Neck Surg. 2006;134:177-9 pubmed
  54. Casler J, Doolittle A, Mair E. Endoscopic surgery of the anterior skull base. Laryngoscope. 2005;115:16-24 pubmed
    Traditional surgical approaches to the anterior skull base often involve craniotomy, facial incisions, disruption of skeletal framework, tracheotomy, and an extended hospital stay...
  55. Alio J, Lorenzo J, Iglesias C. Cranial base growth in patients with Down syndrome: a longitudinal study. Am J Orthod Dentofacial Orthop. 2008;133:729-37 pubmed publisher
    ..The purpose of this study was to assess the growth of the cranial base in a sample of patients diagnosed with Down syndrome (DS)...
  56. Bleier B, Wang E, Vandergrift W, Schlosser R. Mucocele rate after endoscopic skull base reconstruction using vascularized pedicled flaps. Am J Rhinol Allergy. 2011;25:186-7 pubmed publisher
    Postoperative cerebrospinal fluid leak is a significant risk after endoscopic skull base surgery. Recently, novel reconstructive techniques using vascularized pedicled mucosal flaps have been applied to decrease this potential risk...
  57. Bumm K, Heupel J, Bozzato A, Iro H, Hornung J. Localization and infliction pattern of iatrogenic skull base defects following endoscopic sinus surgery at a teaching hospital. Auris Nasus Larynx. 2009;36:671-6 pubmed publisher
    ..We present our results of over 14 years of experience from endoscopic repair of CSF rhinorrhea with long-term follow-up...
  58. Alameda Y, Busquets J, Portela J. Anterior skull base cerebrospinal fluid fistulas in Puerto Rico: treatment and outcome. Bol Asoc Med P R. 2009;101:29-33 pubmed
    The surgical management of anterior skull base cerebrospinal fluid (CSF) fistulas has evolved throughout the last decade...
  59. de Notaris M, Prats Galino A, Cavallo L, Esposito F, Iaconetta G, Gonzalez J, et al. Preliminary experience with a new three-dimensional computer-based model for the study and the analysis of skull base approaches. Childs Nerv Syst. 2010;26:621-6 pubmed publisher
    ..post-dissection Digital Imaging and Communication in Medicine (DICOM) images of both transcranial and endonasal skull base approaches...
  60. Ueda R, Saito R, Horiguchi T, Nakamura Y, Ichikizaki K. Malignant peripheral nerve sheath tumor in the anterior skull base associated with neurofibromatosis type 1--case report. Neurol Med Chir (Tokyo). 2004;44:38-42 pubmed
    A 36-year-old man presented with a tumor in the anterior skull base manifesting as headache and visual disturbance. Neurofibromatosis type 1 (NF-1) was identified in early childhood in the patient, and also in his father...
  61. Chamoun R, Couldwell W. Practical and technical aspects of trans-sphenoidal surgery. J Neurosurg Sci. 2011;55:265-75 pubmed
    ..With enhanced knowledge and understanding of the surgical anatomy of the skull base, the application of extended transsphenoidal approaches became possible, thus widening significantly the ..
  62. Ghegan M, Lee F, Schlosser R. Incidence of skull base and orbital erosion in allergic fungal rhinosinusitis (AFRS) and non-AFRS. Otolaryngol Head Neck Surg. 2006;134:592-5 pubmed
    ..To compare the incidence of bony erosion associated with allergic fungal rhinosinusitis (AFRS) with the incidence of bony erosion seen in other types of inflammatory sinusitis...
  63. Prevedello D, Barges Coll J, Fernandez Miranda J, Morera V, Jacobson D, Madhok R, et al. Middle turbinate flap for skull base reconstruction: cadaveric feasibility study. Laryngoscope. 2009;119:2094-8 pubmed publisher
    ..The purpose of this study is to describe a novel vascularized pedicled flap from the middle turbinate (MT) mucosa and to assess its feasibility using a cadaveric model...
  64. Wise S, DelGaudio J. Computer-aided surgery of the paranasal sinuses and skull base. Expert Rev Med Devices. 2005;2:395-408 pubmed
    ..article, the history of image-guidance systems and their application to surgery of the paranasal sinuses and skull base will be reviewed...
  65. Feiz Erfan I, Horn E, Rekate H, Spetzler R, Ng Y, Rosenfeld J, et al. Surgical strategies for approaching hypothalamic hamartomas causing gelastic seizures in the pediatric population: transventricular compared with skull base approaches. J Neurosurg. 2005;103:325-32 pubmed
    ..The authors provide evidence that direct resection of hypothalamic hamartomas (HHs) can improve associated gelastic and nongelastic seizures...
  66. Woodworth B, Chiu A, Cohen N, Kennedy D, O Malley B, Palmer J. Real-time computed tomography image update for endoscopic skull base surgery. J Laryngol Otol. 2008;122:361-5 pubmed
    ..However, conventional computer-aided systems do not provide intra-operative updated computed tomography imaging. We describe the technical aspects of the xCAT, a new intra-operative mobile volume computed tomography scanner...
  67. Behari S, Tyagi I, Banerji D, Kumar V, Jaiswal A, Phadke R, et al. Postauricular, transpetrous, presigmoid approach for extensive skull base tumors in the petroclival region: the successes and the travails. Acta Neurochir (Wien). 2010;152:1633-45 pubmed publisher
    ..This study reviews the surgical technique, corridors of extension, and complications encountered utilizing this approach for excising extensive lesions in these locations...
  68. Imola M, Sciarretta V, Schramm V. Skull base reconstruction. Curr Opin Otolaryngol Head Neck Surg. 2003;11:282-90 pubmed
    Reconstruction of skull base defects following tumor resection is of paramount importance in avoiding serious and life-threatening complications...
  69. Ogawa Y, Nakagawa A, Takayama K, Tominaga T. Pulsed laser-induced liquid jet for skull base tumor removal with vascular preservation through the transsphenoidal approach: a clinical investigation. Acta Neurochir (Wien). 2011;153:823-30 pubmed publisher
    ..To overcome these problems, we have developed a pulsed laser-induced liquid jet (LILJ) system to dissect tumor tissue with preservation of fine blood vessels within deep and narrow working spaces and evaluated its utility and safety...
  70. Cavallo L, Messina A, Gardner P, Esposito F, Kassam A, Cappabianca P, et al. Extended endoscopic endonasal approach to the pterygopalatine fossa: anatomical study and clinical considerations. Neurosurg Focus. 2005;19:E5 pubmed
    The pterygopalatine fossa is an area located deep in the skull base. The microsurgical transmaxillary-transantral route is usually chosen to remove lesions in this region...
  71. Hanasono M, Silva A, Skoracki R, Gidley P, DeMonte F, Hanna E, et al. Skull base reconstruction: an updated approach. Plast Reconstr Surg. 2011;128:675-86 pubmed publisher
    The authors' goal was to develop an updated and comprehensive algorithm for skull base reconstruction based on data from the 10-year period following their initial report.
  72. Chiu E, Kraus D, Bui D, Mehrara B, Disa J, Bilsky M, et al. Anterior and middle cranial fossa skull base reconstruction using microvascular free tissue techniques: surgical complications and functional outcomes. Ann Plast Surg. 2008;60:514-20 pubmed publisher
    Surgical ablation for oncologic disease requiring skull base resection can result in both facial disfigurement and a complex wound defect with exposed orbital content, oral cavity, bone, and dural lining...
  73. Gardner P, Kassam A, Rothfus W, Snyderman C, Carrau R. Preoperative and intraoperative imaging for endoscopic endonasal approaches to the skull base. Otolaryngol Clin North Am. 2008;41:215-30, vii pubmed publisher
    ..The radiographic evaluation of skull base anatomy and its relationship to associated tumors is critical for both preoperative planning and intraoperative ..
  74. Moyer J, Chepeha D, Teknos T. Contemporary skull base reconstruction. Curr Opin Otolaryngol Head Neck Surg. 2004;12:294-9 pubmed
    Tumors of the skull base that would have been considered inoperable thirty or forty years ago are now routinely resected with reliable results due to the advancement of modern reconstructive techniques...
  75. Strauss G. [Computer-assisted surgery of the frontal skull base]. HNO. 2009;57:990-7 pubmed publisher
    ..Extended approaches in the frontal skull base appear to benefit from the use of navigation support to a high degree...
  76. Yen R, Ting L, Cheng M, Wu Y, Tzen K, Hong R. Usefulness of 201TL SPECT/CT relative to 18F-FDG PET/CT in detecting recurrent skull base nasopharyngeal carcinoma. Head Neck. 2009;31:717-24 pubmed publisher
    This study was designed to compare (201)Tl single photon emission computed tomography (SPECT)/CT with 18-fluoro-2-deoxyglucose ((18)F-FDG) PET/CT in diagnosing recurrent skull base nasopharyngeal carcinoma (NPC).
  77. Feiz Erfan I, Horn E, Theodore N, Zabramski J, Klopfenstein J, Lekovic G, et al. Incidence and pattern of direct blunt neurovascular injury associated with trauma to the skull base. J Neurosurg. 2007;107:364-9 pubmed
    b>Skull base fractures are often associated with potentially devastating injuries to major neural arteries in the head and neck, but the incidence and pattern of this association are unknown.
  78. Kassam A, Gardner P, Snyderman C, Mintz A, Carrau R. Expanded endonasal approach: fully endoscopic, completely transnasal approach to the middle third of the clivus, petrous bone, middle cranial fossa, and infratemporal fossa. Neurosurg Focus. 2005;19:E6 pubmed
    ..third of the clivus and the region around the petrous internal carotid artery (ICA) is a difficult area of the skull base in terms of access...
  79. Peng L, Liu Y, Ai Y, Liu Z, He Y, Liu Q. Skull base metastases from a malignant solitary fibrous tumor of the liver. A case report and literature review. Diagn Pathol. 2011;6:127 pubmed publisher
    ..To our knowledge, this is the first case of malignant solitary fibrous liver tumors with skeletal metastasis...