paranasal sinuses

Summary

Summary: Air-filled spaces located within the bones around the NASAL CAVITY. They are extensions of the nasal cavity and lined by the ciliated NASAL MUCOSA. Each sinus is named for the cranial bone in which it is located, such as the ETHMOID SINUS; the FRONTAL SINUS; the MAXILLARY SINUS; and the SPHENOID SINUS.

Top Publications

  1. Aouad R, Chiu A. State of the art treatment of nasal polyposis. Am J Rhinol Allergy. 2011;25:291-8 pubmed publisher
    ..Nasal polyposis represents the end point of multiple inflammatory pathways and controversy continues as to the exact roles of medical and surgical approaches in the management of nasal polyposis...
  2. Güldner C, Ningo A, Voigt J, Diogo I, Heinrichs J, Weber R, et al. Potential of dosage reduction in cone-beam-computed tomography (CBCT) for radiological diagnostics of the paranasal sinuses. Eur Arch Otorhinolaryngol. 2013;270:1307-15 pubmed publisher
    ..of specific dosages and the identification of potential optimization in the performance of CBCT of the paranasal sinuses. Based on different tube parameters (tube current, tube voltage, and rotation angles), images of the nose ..
  3. Johansen H, Aanaes K, Pressler T, Nielsen K, Fisker J, Skov M, et al. Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response. J Cyst Fibros. 2012;11:525-31 pubmed publisher
    ..We studied whether the sinuses might be foci for Pseudomonas aeruginosa lung infection...
  4. Park H, Seoh J, Han K, Moon K, Lee S. The role of mucosal immunity in fungus ball of the paranasal sinuses. Acta Otolaryngol. 2012;132 Suppl 1:S58-62 pubmed publisher
    ..Increased levels of immunoglobulin (Ig)A, plasma cells, and lymphocytes without infiltration of other inflammatory cells suggest that mucosal immunity may play an important role in paranasal fungus ball...
  5. Soler Z, Mace J, Litvack J, Smith T. Chronic rhinosinusitis, race, and ethnicity. Am J Rhinol Allergy. 2012;26:110-6 pubmed publisher
    ..This study was designed to comprehensively evaluate the current prevalence of CRS across various treatment settings to identify possible disparities in health care access and use between racial and ethnic populations...
  6. Abadie W, McMains K, Weitzel E. Irrigation penetration of nasal delivery systems: a cadaver study. Int Forum Allergy Rhinol. 2011;1:46-9 pubmed publisher
    ..To determine the sinus penetration potential of several commercially available irrigation systems in maximally operated sinus cavities; cadaveric study in a tertiary care center...
  7. Rotenberg B, Zhang I, Arra I, Payton K. Postoperative care for Samter's triad patients undergoing endoscopic sinus surgery: a double-blinded, randomized controlled trial. Laryngoscope. 2011;121:2702-5 pubmed publisher
    ..The purpose of this study was to compare three different standardized medication regimens prescribed to these patients after ESS...
  8. Greenhaw B, Deshazo R, Arnold J, Wright L. Fungal immunotherapy in patients with allergic fungal sinusitis. Ann Allergy Asthma Immunol. 2011;107:432-6 pubmed publisher
    ..Previous studies using fungal immunotherapy reported less recurrence after surgery. There has been concern that traditional high-dose immunotherapy could induce systemic hypersensitivity in patients with this condition...
  9. Campbell P, Zinreich S, Aygun N. Imaging of the paranasal sinuses and in-office CT. Otolaryngol Clin North Am. 2009;42:753-64, vii pubmed publisher
    ..The latest development in CT technology, cone beam CT instrumentation, may change the way imaging of the nasal cavity and paranasal sinuses is performed in the future. These topics are discussed in this article.

More Information

Publications96

  1. Zafar U, Khan N, Afroz N, Hasan S. Clinicopathological study of non-neoplastic lesions of nasal cavity and paranasal sinuses. Indian J Pathol Microbiol. 2008;51:26-9 pubmed
    An analysis of cases presenting as mass in nasal cavity (NC), paranasal sinuses (PNS), and nasopharynx (NP) was done over a period of 7 years in Jawaharlal Nehru Medical College, Aligarh...
  2. Fatterpekar G, Delman B, Som P. Imaging the paranasal sinuses: where we are and where we are going. Anat Rec (Hoboken). 2008;291:1564-72 pubmed publisher
    ..imaging has dramatically changed our approach and understanding of the anatomy and pathology of paranasal sinuses. We have moved away from plain film radiographs to modern high-resolution sinus computerized tomography (CT) ..
  3. Smith T, Mendolia Loffredo S, Loehrl T, Sparapani R, Laud P, Nattinger A. Predictive factors and outcomes in endoscopic sinus surgery for chronic rhinosinusitis. Laryngoscope. 2005;115:2199-205 pubmed
    ..Preoperative CT may be a predictor of endoscopic and QOL outcome and deserves further study. ..
  4. Nitinavakarn B, Thanaviratananich S, Sangsilp N. Anatomical variations of the lateral nasal wall and paranasal sinuses: A CT study for endoscopic sinus surgery (ESS) in Thai patients. J Med Assoc Thai. 2005;88:763-8 pubmed
    Computerized tomography (CT) of the paranasal sinuses is usually required prior to endoscopic sinus surgery...
  5. Bozdemir K, Kutluhan A, Cetin H, Yalciner G, Bilgen A. Comparison of outcomes of simple polypectomy plus balloon catheter dilatation versus functional endoscopic sinus surgery in nasal polyposis: a preliminary study. Am J Rhinol Allergy. 2011;25:198-200 pubmed publisher
    ..BCD was performed on one side of each patient's paranasal sinuses (after nasal polypectomy by microdebrider) while standard FESS was performed on the other side...
  6. Gupta N, Kaur J, Srinivasan R, Das A, Mohindra S, Rajwanshi A, et al. Fine needle aspiration cytology in lesions of the nose, nasal cavity and paranasal sinuses. Acta Cytol. 2011;55:135-41 pubmed publisher
    ..To assess the spectrum of lesions in the sinonasal region diagnosed on FNAC...
  7. Beale T, Madani G, Morley S. Imaging of the paranasal sinuses and nasal cavity: normal anatomy and clinically relevant anatomical variants. Semin Ultrasound CT MR. 2009;30:2-16 pubmed
    ..This article describes the anatomy of the sinonasal region and the clinically relevant anatomical variants, highlighting the need for multiplanar reconstructions as a routine part of the examination when reviewing this region. ..
  8. Snidvongs K, Chaowanapanja P, Aeumjaturapat S, Chusakul S, Praweswararat P. Does nasal irrigation enter paranasal sinuses in chronic rhinosinusitis?. Am J Rhinol. 2008;22:483-6 pubmed publisher
    ..but, in chronic rhinosinusitis, nasal flush is also a potential route for topical drug administration into paranasal sinuses. A clinical study was conducted to investigate how well nasal irrigation could reach paranasal sinuses with ..
  9. Swibel Rosenthal L, Benninger M, Stone C, Zacharek M. Wound healing in the rabbit paranasal sinuses after Coblation: evaluation for use in endoscopic sinus surgery. Am J Rhinol Allergy. 2009;23:360-3 pubmed publisher
    ..This study was performed to determine the extent and pattern of injury in the paranasal sinuses with bipolar radiofrequency and evaluate wound healing...
  10. Mann W, Toth M, Gouveris H, Amedee R. The drainage system of the paranasal sinuses: a review with possible implications for balloon catheter dilation. Am J Rhinol Allergy. 2011;25:245-8 pubmed publisher
    ..ostia of the maxillary sinus are well known to rhinologic surgeons but are less known for the remaining paranasal sinuses. Probing and dilatation of the natural ostia of diseased sinuses is being popularized currently by the ..
  11. Yang P, Wang C, An Z. A murine model of ulcerative colitis: induced with sinusitis-derived superantigen and food allergen. BMC Gastroenterol. 2005;5:6 pubmed
    ..The SWF facilitated colonic mucosal sensitization to luminal antigen. Multiple challenging the sensitized colonic mucosa with specific antigen OVA induced inflammation, induced a condition similar to human ulcerative colitis. ..
  12. Romashko A, Stankiewicz J. Routine histopathology in uncomplicated sinus surgery: is it necessary?. Otolaryngol Head Neck Surg. 2005;132:407-12; discussion 413 pubmed
    ..To evaluate the incidence of occult pathology in routine, uncomplicated endoscopic sinus surgery, and to suggest guidelines for when to send specimens for histopathologic exam...
  13. Lundberg J. Nitric oxide and the paranasal sinuses. Anat Rec (Hoboken). 2008;291:1479-84 pubmed publisher
    The discovery within the paranasal sinuses for the production of nitric oxide (NO) has altered the traditional explanations of sinus physiology...
  14. Affolter A, Helmbrecht S, Finger S, Hormann K, Gotte K. Altered expression of cell cycle regulators p21, p27, and p53 in tumors of salivary glands and paranasal sinuses. Oncol Rep. 2005;13:1089-94 pubmed
    ..and compare the expression of p21, p27, and p53 in benign and malignant tumors of salivary glands and paranasal sinuses. Protein expression was detected by conventional immunohistochemistry (IHC)...
  15. Combs S, Konkel S, Schulz Ertner D, Munter M, Debus J, Huber P, et al. Intensity modulated radiotherapy (IMRT) in patients with carcinomas of the paranasal sinuses: clinical benefit for complex shaped target volumes. Radiat Oncol. 2006;1:23 pubmed
    ..We treated 46 patients with histologically proven tumors of the paranasal sinuses with IMRT...
  16. Wise S, Venkatraman G, Wise J, DelGaudio J. Ethnic and gender differences in bone erosion in allergic fungal sinusitis. Am J Rhinol. 2004;18:397-404 pubmed
    ..028). In addition, there are statistically significant differences in the individual paranasal sinuses affected by bone erosion in AFS...
  17. Dammann F. [Imaging of paranasal sinuses today]. Radiologe. 2007;47:576, 578-83 pubmed
    ..in malignant disease or complications of inflammatory sinus disease that extend beyond the limits of the paranasal sinuses. The clinical value of other imaging modalities, including plain film radiography, ultrasound, or ..
  18. Marple B. Allergic rhinitis and inflammatory airway disease: interactions within the unified airspace. Am J Rhinol Allergy. 2010;24:249-54 pubmed publisher
    ..AR pharmacotherapies include antihistamines, leukotriene antagonists, intranasal corticosteroids, and immunotherapy; treatments attenuating proinflammatory responses may also benefit associated conditions. ..
  19. Azbell C, Zhang S, Skinner D, Fortenberry J, Sorscher E, Woodworth B. Hesperidin stimulates cystic fibrosis transmembrane conductance regulator-mediated chloride secretion and ciliary beat frequency in sinonasal epithelium. Otolaryngol Head Neck Surg. 2010;143:397-404 pubmed publisher
    ..26 +/- 0.18 vs 1.60 +/- 0.21, respectively; P < 0.05). Our in vitro and in vivo investigations provide strong support for future testing of this robust Cl(-) secretagogue and CBF activator in human clinical trials for CRS. ..
  20. Sanclement J, Webster P, Thomas J, Ramadan H. Bacterial biofilms in surgical specimens of patients with chronic rhinosinusitis. Laryngoscope. 2005;115:578-82 pubmed
    ..We were able to demonstrate evidence of bacteria in the biofilms on the subjects tested using TEM. ..
  21. Keir J. Why do we have paranasal sinuses?. J Laryngol Otol. 2009;123:4-8 pubmed publisher
    The paranasal sinuses, comprising the frontal, maxillary, ethmoid and sphenoid sinuses, have caused consternation and debate over their true function over the course of nearly two millennia...
  22. Ahn H, Chung S, Dhong H, Kim H, Ahn J, Lee S, et al. Comparison of surgical conditions during propofol or sevoflurane anaesthesia for endoscopic sinus surgery. Br J Anaesth. 2008;100:50-4 pubmed
    ..In the high-LM score patients, PR anaesthesia results in less blood loss and a better surgical conditions for ESS than SR anaesthesia. ..
  23. Casteleyn C, Cornillie P, Hermens A, Van Loo D, Van Hoorebeke L, van den Broeck W, et al. Topography of the rabbit paranasal sinuses as a prerequisite to model human sinusitis. Rhinology. 2010;48:300-4 pubmed publisher
    ..The absence of frontal and ethmoidal sinuses in any of the rabbits examined is a major difference between the rabbit and human sinuses. The rabbit maxillary sinus seems most appropriate for experimental work. ..
  24. Baroody F. Nasal and paranasal sinus anatomy and physiology. Clin Allergy Immunol. 2007;19:1-21 pubmed
  25. Stankiewicz J, Tami T, Truitt T, Atkins J, Liepert D, Winegar B. Transantral, endoscopically guided balloon dilatation of the ostiomeatal complex for chronic rhinosinusitis under local anesthesia. Am J Rhinol Allergy. 2009;23:321-7 pubmed publisher
  26. Uzun C. Paranasal sinus barotrauma in sports self-contained underwater breathing apparatus divers. J Laryngol Otol. 2009;123:80-4 pubmed publisher
    ..TO evaluate potential pre-dive parameters in relation to paranasal sinus barotrauma in sports self-contained underwater breathing apparatus divers...
  27. Baker A, Baker A. Anaesthesia for endoscopic sinus surgery. Acta Anaesthesiol Scand. 2010;54:795-803 pubmed publisher
    ..Post-operatively, multimodal oral analgesia provides good pain relief, while long-acting local anaesthetics have been shown not to improve analgesia. ..
  28. Zhang S, Fortenberry J, Cohen N, Sorscher E, Woodworth B. Comparison of vectorial ion transport in primary murine airway and human sinonasal air-liquid interface cultures, models for studies of cystic fibrosis, and other airway diseases. Am J Rhinol Allergy. 2009;23:149-52 pubmed publisher
    ..Human sinonasal and murine septal epithelial cultures represent a useful model for studying CFTR activity and may provide significant advantages over lower airway tissues for investigating upper and lower respiratory pathophysiology. ..
  29. Durand M, Pourchez J, Aubert G, Le Guellec S, Navarro L, Forest V, et al. Impact of acoustic airflow nebulization on intrasinus drug deposition of a human plastinated nasal cast: new insights into the mechanisms involved. Int J Pharm. 2011;421:63-71 pubmed publisher
    ..The influence of drug concentration and endonasal anatomical features on the sinus deposition enhanced by the 100 Hz acoustic airflow was also examined...
  30. Weitzel E, McMains K, Rajapaksa S, Wormald P. Aerosinusitis: pathophysiology, prophylaxis, and management in passengers and aircrew. Aviat Space Environ Med. 2008;79:50-3 pubmed
    ..Aircrew that suffer Stage III aerosinusitis are at risk for recurrent sinus barotrauma that may require an expertly performed functional endoscopic sinus surgery to successfully manage it...
  31. Kim J, Song S, Cho J, Chang K, Jun B. Comparative study of the pneumatization of the mastoid air cells and paranasal sinuses using three-dimensional reconstruction of computed tomography scans. Surg Radiol Anat. 2010;32:593-9 pubmed publisher
    ..The purpose of this study was to investigate the relationship between the pneumatization of mastoid air cells and PNS using three-dimensional (3D) reconstruction of computed tomography (CT) scans of the PNS...
  32. Chao T. Uncommon anatomic variations in patients with chronic paranasal sinusitis. Otolaryngol Head Neck Surg. 2005;132:221-5 pubmed
    ..Uncommon anatomic variations, though unusual, are not rare in chronic paranasal sinusitis patients. Procedures should be tailored for most of these special conditions. ..
  33. Yiotakis J, Vamvakidis T, Iakovou E, Manolopoulos L. Aggressive verrucous carcinoma of the paranasal sinuses invading the orbit: case report and literature review. J Laryngol Otol. 2009;123:e23 pubmed publisher
    ..Verrucous carcinoma is a variant of well differentiated squamous cell carcinoma characterised by an exophytic, warty growth which is slowly but locally invasive and which can cause extensive local destruction if left untreated...
  34. Chakrabarti A, Denning D, Ferguson B, Ponikau J, Buzina W, Kita H, et al. Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies. Laryngoscope. 2009;119:1809-18 pubmed publisher
    ..However, consensus on terminology, pathogenesis, and optimal management is lacking. The International Society for Human and Animal Mycology convened a working group to attempt consensus on terminology and disease classification...
  35. Park I, Song J, Choi H, Kim T, Hoon S, Lee S, et al. Volumetric study in the development of paranasal sinuses by CT imaging in Asian: a pilot study. Int J Pediatr Otorhinolaryngol. 2010;74:1347-50 pubmed publisher
    The volume of the air cavities in the paranasal sinuses is not only the simplest, but also the most important index for paranasal sinus evaluation. However, few volumetric studies have been performed in all age groups...
  36. Pirner S, Tingelhoff K, Wagner I, Westphal R, Rilk M, Wahl F, et al. CT-based manual segmentation and evaluation of paranasal sinuses. Eur Arch Otorhinolaryngol. 2009;266:507-18 pubmed publisher
    ..None of the segmentation methods so far described provide risk segmentation. The robot's maximum distance to the segmented border can be adjusted according to the differently colored areas...
  37. Składzieriń J, Oles K, Zagolski O, Moskała M, Sztuka M, Strek P, et al. A giant cranial aneurysmal bone cyst associated with fibrous dysplasia. B-ENT. 2008;4:29-33 pubmed
    ..CT scans showed a predominantly cystic, expansive mass obstructing both nasal cavities, extending to all paranasal sinuses and both orbits, with evidence of anterior cranial fossa skull base destruction...
  38. Babin E, Rouleau V, Vedrine P, Toussaint B, De Raucourt D, Malard O, et al. Small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses. J Laryngol Otol. 2006;120:289-97 pubmed
    ..Small cell neuroendocrine carcinoma (SNEC) of the sinonasal tract is a rare disease...
  39. Hamilton Farrell M, Bhattacharyya A. Barotrauma. Injury. 2004;35:359-70 pubmed
    ..The management of these problems includes prevention, the use of pressure-equalizing techniques, vasoconstrictor drugs, surgery, and hyperbaric oxygen therapy...
  40. Coffey C, Sonnenburg R, Melroy C, Dubin M, Senior B. Endoscopically guided aerobic cultures in postsurgical patients with chronic rhinosinusitis. Am J Rhinol. 2006;20:72-6 pubmed
    ..debate in the literature regarding the microbial flora of normal, acutely infected, and chronically infected paranasal sinuses. Few studies have specifically looked at the microbial flora of healthy and infected sinus cavities after ..
  41. Caversaccio M, Zheng G, Nolte L. [Computer-aided surgery of the paranasal sinuses and the anterior skull base]. HNO. 2008;56:376-8, 780-2 pubmed publisher
    ..Computer-aided surgery also has great potential for education...
  42. Kantarci M, Karasen R, Alper F, Onbas O, Okur A, Karaman A. Remarkable anatomic variations in paranasal sinus region and their clinical importance. Eur J Radiol. 2004;50:296-302 pubmed
    ..The radiologist must pay close attention to anatomical variations in the preoperative evaluation...
  43. Kokan N, Hosomi Y, Inamoto S, Ohnishi K, Tanimoto H, Nibu K. Microscopic polyangiitis histologically confirmed by biopsy from nasal cavity and paranasal sinuses: a case report. Rheumatol Int. 2006;26:936-8 pubmed
    ..Pathological findings revealed vasculitis of small vessels in the mucosal surface. MPA was diagnosed on the basis of clinical symptoms, elevated MPO-ANCA and the pathological findings of the nasal and paranasal surgical specimen...
  44. Mazza D, Bontempi E, Guerrisi A, Del Monte S, Cipolla G, Perrone A, et al. Paranasal sinuses anatomic variants: 64-slice CT evaluation. Minerva Stomatol. 2007;56:311-8 pubmed
    The aim of the paper was to perform a 64-slice CT evaluation of the main anatomic variants of paranasal sinuses.
  45. Dijkstra M, Ebbens F, Poublon R, Fokkens W. Fluticasone propionate aqueous nasal spray does not influence the recurrence rate of chronic rhinosinusitis and nasal polyps 1 year after functional endoscopic sinus surgery. Clin Exp Allergy. 2004;34:1395-400 pubmed
    ..Their efficacy after functional endoscopic sinus surgery (FESS) has not been fully established by placebo-controlled trials...
  46. Emirzeoglu M, Sahin B, Bilgic S, Celebi M, Uzun A. Volumetric evaluation of the paranasal sinuses in normal subjects using computer tomography images: a stereological study. Auris Nasus Larynx. 2007;34:191-5 pubmed
    The size and shape of paranasal sinuses are especially relevant when considering endoscopic sinus surgery...
  47. Boyce J, Eccles R. Do chronic changes in nasal airflow have any physiological or pathological effect on the nose and paranasal sinuses? A systematic review. Clin Otolaryngol. 2006;31:15-9 pubmed
    ..Such studies provide evidence that reduced nasal airflow causes no significant nasal disease. . There is no convincing evidence that a reduction in nasal airflow is a causative factor for rhinitis or sinusitis...
  48. Moeller W, Schuschnig U, Meyer G, Häussinger K, Keller M, Junge Hülsing B, et al. Ventilation and aerosolized drug delivery to the paranasal sinuses using pulsating airflow - a preliminary study. Rhinology. 2009;47:405-12 pubmed publisher
    ..including chronic sinusitis, there is limited success in the topical drug delivery to the nose and the paranasal sinuses. This is caused by the nose being an efficient filter for inhaled aerosol particles and the paranasal ..
  49. Kim H, Jung Cho M, Lee J, Tae Kim Y, Kahng H, Sung Kim H, et al. The relationship between anatomic variations of paranasal sinuses and chronic sinusitis in children. Acta Otolaryngol. 2006;126:1067-72 pubmed
    Anatomical variations in the nose and paranasal sinuses are common in children...
  50. Lee J, Byun J, Shim S, Lee S. Outcomes after endoscopic sinus surgery for unilateral versus bilateral chronic rhinosinusitis with nasal polyposis. Am J Rhinol Allergy. 2010;24:83-6 pubmed publisher
    ..Because no study has been conducted on the surgical outcomes between unilateral and bilateral CRS with NP after ESS, we evaluated subjective and objective outcomes between patients with unilateral and bilateral CRS with NP...
  51. Hepworth E, Bucknor M, Patel A, Vaughan W. Nationwide survey on the use of image-guided functional endoscopic sinus surgery. Otolaryngol Head Neck Surg. 2006;135:68-73 pubmed
    ..To evaluate impressions and usage of sinus surgery image-guided surgical (IGS) systems by ENT surgeons in the United States...
  52. Maniscalco M, Sofia M, Weitzberg E, Lundberg J. Sounding airflow enhances aerosol delivery into the paranasal sinuses. Eur J Clin Invest. 2006;36:509-13 pubmed
    ..produced by phonation (nasal humming) causes a large increase in the gas exchange between the nose and the paranasal sinuses. This is reflected by a high peak in nasally exhaled nitric oxide (NO) levels because NO accumulated in the ..
  53. Eller R, Sillers M. Common fibro-osseous lesions of the paranasal sinuses. Otolaryngol Clin North Am. 2006;39:585-600, x pubmed
    Within in the broad spectrum of disease that can affect the paranasal sinuses is a class of benign bony abnormalities known collectively as fibro-osseous lesions...
  54. Kasapoglu F, Coskun H, Ozmen O, Akalin H, Ener B. Acute invasive fungal rhinosinusitis: evaluation of 26 patients treated with endonasal or open surgical procedures. Otolaryngol Head Neck Surg. 2010;143:614-20 pubmed publisher
    ..Our purpose was to present the diagnostic and therapeutic management and outcome of these patients...
  55. Lee W, Ramanathan M, Spannhake E, Lane A. The cigarette smoke component acrolein inhibits expression of the innate immune components IL-8 and human beta-defensin 2 by sinonasal epithelial cells. Am J Rhinol. 2007;21:658-63 pubmed publisher
    ..In this study, we explore whether exposure of human sinonasal epithelial cells (HSNECs) to AC similarly reduces their innate immune gene expression...
  56. Schubert M. Allergic fungal sinusitis: pathophysiology, diagnosis and management. Med Mycol. 2009;47 Suppl 1:S324-30 pubmed publisher
    ..rhinosinusitis that often include central areas of increased contrast ('hyperattenuation') within abnormal paranasal sinuses that represent the presence of fungal-containing allergic mucin...
  57. Swibel Rosenthal L, Benninger M, Stone C, Zacharek M. Wound healing in the paranasal sinuses after Coblation, Part II: evaluation for endoscopic sinus surgery using a sheep model. Am J Rhinol Allergy. 2010;24:464-6 pubmed publisher
    ..This study was designed to further understand the pattern of injury using the bipolar radiofrequency plasma process used by the Coblator and evaluate postprocedure healing...
  58. Möller W, Schuschnig U, Meyer G, Mentzel H, Keller M. Ventilation and drug delivery to the paranasal sinuses: studies in a nasal cast using pulsating airflow. Rhinology. 2008;46:213-20 pubmed
    ..including chronic sinusitis, there is limited success in the topical drug delivery to the nose and the paranasal sinuses. This is caused by the nose being an efficient filter for inhaled aerosol particles and the paranasal ..
  59. Márquez S, Tessema B, Clement P, Schaefer S. Development of the ethmoid sinus and extramural migration: the anatomical basis of this paranasal sinus. Anat Rec (Hoboken). 2008;291:1535-53 pubmed publisher
    ..patient care has consequently driven the need for the proper and accurate anatomical description of the paranasal sinuses, regrettably the continuing subject of persistent confusion and ambiguity in nomenclature and terminology...
  60. Khalid A, Quraishi S, Kennedy D. Long-term quality of life measures after functional endoscopic sinus surgery. Am J Rhinol. 2004;18:131-6 pubmed
    ..The aim of this study was to evaluate the longer-term effects of combined medical and surgical therapy for CRS on overall health status and QOL...
  61. Hansen S, Rau M, Johansen H, Ciofu O, Jelsbak L, Yang L, et al. Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection. ISME J. 2012;6:31-45 pubmed publisher
    ..established sinus surgery treatment program for CF patients at the Copenhagen CF Center, colonization of the paranasal sinuses with P. aeruginosa has been investigated, paralleled by sampling of sputum from the same patients...
  62. Ehnhage A, Olsson P, Kolbeck K, Skedinger M, Dahlen B, Alenius M, et al. Functional endoscopic sinus surgery improved asthma symptoms as well as PEFR and olfaction in patients with nasal polyposis. Allergy. 2009;64:762-9 pubmed publisher
    ..The management is anti-inflammatory, with topical and oral corticosteroids as the first-line treatment. The effect of surgical treatment on lower airway inflammation has not been sufficiently studied...
  63. Pifferi M, Bush A, Caramella D, Di Cicco M, Zangani M, Chinellato I, et al. Agenesis of paranasal sinuses and nasal nitric oxide in primary ciliary dyskinesia. Eur Respir J. 2011;37:566-71 pubmed publisher
    Agenesis of paranasal sinuses has only been described in case reports of patients with primary ciliary dyskinesia (PCD)...
  64. Ghegan M, Wise S, Gorham E, Schlosser R. Socioeconomic factors in allergic fungal rhinosinusitis with bone erosion. Am J Rhinol. 2007;21:560-3 pubmed
    ..The aim of this study was to evaluate the contribution of race, ethnicity, and various socioeconomic factors to the advanced presentation of AFRS with orbital and skull base bone erosion...
  65. Tsao Y, Kao C, Wang H, Chin S, Moe K. Transorbital penetrating injury of paranasal sinuses and anterior skull base by a plastic chair glide: management options of a foreign body in multiple anatomic compartments. Otolaryngol Head Neck Surg. 2006;134:177-9 pubmed
  66. Gallup A, Hack G. Human paranasal sinuses and selective brain cooling: a ventilation system activated by yawning?. Med Hypotheses. 2011;77:970-3 pubmed publisher
    The function of the paranasal sinuses has been a controversial subject since the time of Galen, with many different theories advanced about their biological significance...
  67. Grobler A, Weitzel E, Buele A, Jardeleza C, Cheong Y, Field J, et al. Pre- and postoperative sinus penetration of nasal irrigation. Laryngoscope. 2008;118:2078-81 pubmed publisher
    ..The aim of this study is to determine a critical ostial size at which douching solution reliably enters the sinus cavities...
  68. Marseglia G, Castellazzi A, Licari A, Marseglia A, Leone M, Pagella F, et al. Inflammation of paranasal sinuses: the clinical pattern is age-dependent. Pediatr Allergy Immunol. 2007;18 Suppl 18:10-2 pubmed
  69. Wise S, Kingdom T, McKean L, DelGaudio J, Venkatraman G. Presence of fungus in sinus cultures of cystic fibrosis patients. Am J Rhinol. 2005;19:47-51 pubmed
    ..The bacteriology of sinus cultures from CF patients and the implications of sinus bacterial pathogens in this group have been studied; however, sinus fungal isolates from CF patients have not been examined in the literature...
  70. Wormald P, van Renen G, Perks J, Jones J, Langton Hewer C. The effect of the total intravenous anesthesia compared with inhalational anesthesia on the surgical field during endoscopic sinus surgery. Am J Rhinol. 2005;19:514-20 pubmed
    ..The aim of this study was to compare the surgical field in patients in whom total intravenous anesthesia (TIVA) is used as opposed to inhalation anesthesia. A prospective randomized controlled trial was performed...
  71. Saijo R, Majima Y, Hyo N, Takano H. Particle deposition of therapeutic aerosols in the nose and paranasal sinuses after transnasal sinus surgery: a cast model study. Am J Rhinol. 2004;18:1-7 pubmed
    ..The topical administration of steroids or antibiotics to the nose and the sinuses is one of the important postsurgical therapies of endoscopic sinus surgery (ESS)...
  72. Sonmez G, Uzun G, Mutluoglu M, Toklu A, Mutlu H, Ay H, et al. Paranasal sinus mucosal hypertrophy in experienced divers. Aviat Space Environ Med. 2011;82:992-4 pubmed
    ..In this study, we used magnetic resonance imaging (MRI) to compare asymptomatic divers with control subjects for PSMH...
  73. Hojreh A, Czerny C, Kainberger F. Dose classification scheme for computed tomography of the paranasal sinuses. Eur J Radiol. 2005;56:31-7 pubmed
    ..The purpose of this study was to define objective and reproducible standards for the quality of CT images as a function of radiation doses and therapeutic validity...
  74. De Zani D, Borgonovo S, Biggi M, Vignati S, Scandella M, Lazzaretti S, et al. Topographic comparative study of paranasal sinuses in adult horses by computed tomography, sinuscopy, and sectional anatomy. Vet Res Commun. 2010;34 Suppl 1:S13-6 pubmed publisher
    Clinical and radiographic investigations of paranasal sinuses in horses are difficult due to the complex anatomy of these regions, the lack of patognomonic symptoms, and the low sensitivity of conventional diagnostic techniques...
  75. Möller W, Schuschnig U, Khadem Saba G, Meyer G, Junge Hülsing B, Keller M, et al. Pulsating aerosols for drug delivery to the sinuses in healthy volunteers. Otolaryngol Head Neck Surg. 2010;142:382-8 pubmed publisher
  76. Pea F, Marioni G, Pavan F, Staffieri C, Bottin R, Staffieri A, et al. Penetration of levofloxacin into paranasal sinuses mucosa of patients with chronic rhinosinusitis after a single 500 mg oral dose. Pharmacol Res. 2007;55:38-41 pubmed
    ..The aim of this study was to assess levofloxacin penetration into paranasal sinuses mucosa of 15 patients with chronic rhinosinusitis 1h (n = 4), 2 h (n = 5) and 3 h (n = 6) after a single 500 ..
  77. Strek P, Zagolski O, Składzień J, Kurzyński M, Dyduch G. Osteomas of the paranasal sinuses: surgical treatment options. Med Sci Monit. 2007;13:CR244-50 pubmed
    Osteomas are relatively common, benign, slow-growing, often asymptomatic neoplasms of the paranasal sinuses occurring mainly in the frontal and ethmoid sinuses...
  78. Wise S, Rogers G, Ghegan M, Harvey R, DelGaudio J, Schlosser R. Radiologic staging system for allergic fungal rhinosinusitis (AFRS). Otolaryngol Head Neck Surg. 2009;140:735-40 pubmed publisher
    ..1) Develop an objective method for quantifying radiologic bone erosion in allergic fungal rhinosinusitis (AFRS); and 2) assess the utility of the new CT scan staging system in differentiating AFRS patient groups...
  79. Ruskell G. Orbital passage of pterygopalatine ganglion efferents to paranasal sinuses and nasal mucosa in man. Cells Tissues Organs. 2003;175:223-8 pubmed
    ..enter the orbit apically, branch and enter the posterior ethmoidal foramen terminating in the lining of the paranasal sinuses and others advance to enter the anterior ethmoidal canal to reach the nasal mucosa...
  80. Camargo R, Tuon F, Sumi D, Gebrim E, Imamura R, Nicodemo A, et al. Mucosal leishmaniasis and abnormalities on computed tomographic scans of paranasal sinuses. Am J Trop Med Hyg. 2010;83:515-8 pubmed publisher
    ..The aim of this study was to analyze alterations of the paranasal sinuses in patients with ML by using computed tomography (CT) scans...
  81. Moller W, Saba G, Häussinger K, Becker S, Keller M, Schuschnig U. Nasally inhaled pulsating aerosols: lung, sinus and nose deposition. Rhinology. 2011;49:286-91 pubmed publisher
  82. Triulzi F. Diagnostic imaging of the pediatric nasal cavity and paranasal sinuses. Int J Immunopathol Pharmacol. 2010;23:41-4 pubmed
    The vast majority of nasal and paranasal sinuses (PNS) diseases in childhood are of inflammatory origin. In particular, during the early rapid development of PNS rhinosinusitis are exceedingly frequent in both acute and chronic forms...
  83. Eggesbø H. Radiological imaging of inflammatory lesions in the nasal cavity and paranasal sinuses. Eur Radiol. 2006;16:872-88 pubmed
    ..Computed tomography (CT) is the primary modality in diagnosing and mapping suspected inflammatory sinonasal disease. Magnetic resonance (MR) imaging is complementary to CT if fungal sinusitis, pyocele or malignancy are suspected...
  84. Ramanathan M, Lane A. Innate immunity of the sinonasal cavity and its role in chronic rhinosinusitis. Otolaryngol Head Neck Surg. 2007;136:348-56 pubmed
    ..This review will outline our current knowledge of sinonasal innate immunity, the role of innate immunity in the pathogenesis of CRS, and potential therapeutic targets in the innate immune system...
  85. Tingelhoff K, Moral A, Kunkel M, Rilk M, Wagner I, Eichhorn K, et al. Comparison between manual and semi-automatic segmentation of nasal cavity and paranasal sinuses from CT images. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:5505-8 pubmed
    ..semi-automatic segmentation is adequate for ENT surgical workflow or whether fully automatic segmentation of paranasal sinuses and nasal cavity is needed...
  86. Psaltis A, Weitzel E, Ha K, Wormald P. The effect of bacterial biofilms on post-sinus surgical outcomes. Am J Rhinol. 2008;22:1-6 pubmed publisher
    ..This study was performed to evaluate the role that bacterial biofilms have on post-sinus surgical outcomes...
  87. Friedman M, Schalch P, Lin H, Mazloom N, Neidich M, Joseph N. Functional endoscopic dilatation of the sinuses: patient satisfaction, postoperative pain, and cost. Am J Rhinol. 2008;22:204-9 pubmed publisher
    ..A retrospective study was performed of 70 patients with chronic rhinosinusitis who underwent FEDS or FESS as primary or revision treatment...