cochlear aqueduct

Summary

Summary: A fine channel that passes through the TEMPORAL BONE near the SCALA TYMPANI (the basilar turn of the cochlea). The cochlear aqueduct connects the PERILYMPH-filled bony labyrinth to the SUBARACHNOID SPACE.

Top Publications

  1. Calmels M, Deguine O. Perilymphatic fistula. Ear Nose Throat J. 2004;83:666 pubmed
  2. Laurens Thalen E, Wit H, Segenhout J, Albers F. Direct measurement flow resistance of cochlear aqueduct in guinea pigs. Acta Otolaryngol. 2004;124:670-4 pubmed
    The cochlear aqueduct connects the scala tympani to the subarachnoid space and is the main pressure equalization canal for the inner ear...
  3. Wit H, Feijen R, Albers F. Cochlear aqueduct flow resistance is not constant during evoked inner ear pressure change in the guinea pig. Hear Res. 2003;175:190-9 pubmed
    ..ear pressure change the calculated flow resistance of the inner ear pressure release routes (mainly the cochlear aqueduct) was approximately constant, with a value of 12 Pa s/nl (averaged over two ears), when values for the inner ..
  4. Magnano M, Albera R, Lerda W, Usai A, Milan F, Giordano L, et al. [Evaluation of the cochlear aqueduct patency: comparison of 2 noninvasive techniques]. Acta Otorhinolaryngol Ital. 1997;17:403-8 pubmed
    Variations in cephalo-rachidian fluid pressure can be transmitted to the middle ear through the cochlear aqueduct (CA)...
  5. Feijen R, Segenhout J, Albers F, Wit H. Cochlear aqueduct flow resistance depends on round window membrane position in guinea pigs. J Assoc Res Otolaryngol. 2004;5:404-10 pubmed
    The resistance for fluid flow of the cochlear aqueduct was measured in guinea pigs for different positions of the round window membrane...
  6. Ghiz A, Salt A, DeMott J, Henson M, Henson O, Gewalt S. Quantitative anatomy of the round window and cochlear aqueduct in guinea pigs. Hear Res. 2001;162:105-12 pubmed
    ..D. 0.08, n=6). The length and variation of cross-sectional area as a function of distance for the cochlear aqueduct was determined in five specimens...
  7. Traboulsi R, Avan P. Transmission of infrasonic pressure waves from cerebrospinal to intralabyrinthine fluids through the human cochlear aqueduct: Non-invasive measurements with otoacoustic emissions. Hear Res. 2007;233:30-9 pubmed
    The cochlear aqueduct connecting intralabyrinthine and cerebrospinal fluids (CSF) acts as a low-pass filter that should be able to transmit infrasonic pressure waves from CSF to cochlea...
  8. Hofman R, Segenhout J, Albers F, Wit H. The relationship of the round window membrane to the cochlear aqueduct shown in three-dimensional imaging. Hear Res. 2005;209:19-23 pubmed
    The round window membrane and cochlear aqueduct complex in the guinea pig are reconstructed with 3D-imaging, using orthogonal plane fluorescence optical sectioning (OPFOS)...
  9. Miranda J, Suzuki F, de Carvalho Borges M. Perilymphatic hyperension. Braz J Otorhinolaryngol. 2006;72:430 pubmed

More Information

Publications62

  1. Kusuma S, Liou S, Haynes D. Disequilibrium after cochlear implantation caused by a perilymph fistula. Laryngoscope. 2005;115:25-6 pubmed
    ..Further workup of this patient revealed radiographic findings suggestive of a perilymphatic fistula, with immediate and complete resolution of symptoms after exploratory tympanotomy and packing around the cochleostomy...
  2. Klokker M, Vesterhauge S. Perilymphatic fistula in cabin attendants: an incapacitating consequence of flying with common cold. Aviat Space Environ Med. 2005;76:66-8 pubmed
    ..Only one CA has been able to return to flying duties. The article emphasizes the risk of flying with poor middle ear equalization and the necessity of reminding crews and airline companies to "never fly with a common cold"...
  3. Feijen R, Segenhout J, Albers F, Wit H. Change of guinea pig inner ear pressure by square wave middle ear cavity pressure variation. Acta Otolaryngol. 2002;122:138-45 pubmed
    ..The results could not be described using a linear model with constant window membrane compliance and cochlear aqueduct flow resistance...
  4. Karhuketo T, Puhakka H. Endoscope-guided round window fistula repair. Otol Neurotol. 2001;22:869-73 pubmed
    ..Endoscope-guided round window membrane repair was performed to evaluate whether the approach is feasible in the treatment of a round window fistula...
  5. Naganawa S, Koshikawa T, Fukatsu H, Ishigaki T, Fukuta T. MR cisternography of the cerebellopontine angle: comparison of three-dimensional fast asymmetrical spin-echo and three-dimensional constructive interference in the steady-state sequences. AJNR Am J Neuroradiol. 2001;22:1179-85 pubmed
    ..MR cisternography has been used as the noninvasive screening tool of the cerebellopontine angle. The purpose of this study was to directly compare two currently dominant types of sequences for heavily T2-weighted MR cisternography...
  6. Portmann D, Souza Leao F, Bussières R, Noyon P. [Validation of a clinical scale for the diagnosis of perilymphatic fistula]. Rev Laryngol Otol Rhinol (Bord). 2005;126:243-8 pubmed
    ..The goal of this article is to study the clinical situations where you must suspect a PLF and to support a clinical scale described in a previous work (Bussières et al 2003)...
  7. Nuttall A, Zheng J, Ren T, de Boer E. Electrically evoked otoacoustic emissions from apical and basal perilymphatic electrode positions in the guinea pig cochlea. Hear Res. 2001;152:77-89 pubmed
    ..A preliminary model study indicates that short time delayed emissions are the result of a large spatial distribution of current applied to perilymphatic locations possibly giving rise to "wave-fixed" emissions...
  8. Jung N, Moon W, Lee M, Chung E. Magnetic resonance cisternography: comparison between 3-dimensional driven equilibrium with sensitivity encoding and 3-dimensional balanced fast-field echo sequences with sensitivity encoding. J Comput Assist Tomogr. 2007;31:588-91 pubmed
  9. Crawford A, McGrath N. Hearing loss after lumbar puncture. J Clin Neurosci. 2010;17:149-52 pubmed publisher
    ..He was subsequently found to have stenosis of the distal left transverse sinus, which was treated with stenting...
  10. Fritzsch B. How does the urodele ear develop?. Int J Dev Biol. 1996;40:763-71 pubmed
  11. Ozveren M, Ture U, Ozek M, Pamir M. Anatomic landmarks of the glossopharyngeal nerve: a microsurgical anatomic study. Neurosurgery. 2003;52:1400-10; discussion 1410 pubmed
    ..This study aims to disclose the course of the GPhN and point out landmarks to aid in its exposure...
  12. Nakamura T, Naganawa S, Fukatsu H, Sakurai Y, Aoki I, Ninomiya A, et al. Contrast enhancement of the cochlear aqueduct in MR imaging: its frequency and clinical significance. Neuroradiology. 2003;45:626-30 pubmed
    There have been no previous reports on contrast enhancement of the cochlear aqueduct in magnetic resonance imaging. The purpose of the present study was to evaluate the frequency and significance of this finding...
  13. Park M, Lee H, Kim H, Oh S, Lee J, Suh M. Differences in perilymphatic space enhancement and adverse inflammatory reaction after intratympanic injection of two different gadolinium agents: A 9.4-T magnetic resonance imaging study. Hear Res. 2016;333:118-126 pubmed publisher
    ..4 ± 6.6 dB SPL) post-injection. Gd-DTPA was superior to Gd-DTPA-BMA for visualization of the inner ear. Administration of diluted Gd agents intratympanically may induce considerable inflammatory reactions in the inner ear. ..
  14. Angelard B, Francois M, Viala P, Narcy P. [Perilymphatic fistula]. Ann Otolaryngol Chir Cervicofac. 1991;108:446-50 pubmed
    ..Further studies are needed, especially to better understand the pathophysiology of the perilymphatic fistulae, and their results must certainly be appreciated in the longer term...
  15. Can I, Gocmen H, Kurt A, Samim E. Sudden hearing loss due to large vestibular aqueduct syndrome in a child: should exploratory tympanotomy be performed?. Int J Pediatr Otorhinolaryngol. 2004;68:841-4 pubmed
    ..Thyroid function tests and neck palpation were normal. It was an unusual case with both large vestibular aqueduct syndrome (LVAS) and simultaneous spontaneous perilymph fistula...
  16. Traccis S, Zoroddu G, Zecca M, Cau T, Solinas M, Masuri R. Evaluating patients with vertigo: bedside examination. Neurol Sci. 2004;25 Suppl 1:S16-9 pubmed
    ..This article reviews the most common peripheral and central vestibular syndromes as well as the key elements of the bedside vestibular system examination...
  17. Böhmer A. On the pathomechanism of cochlear dysfunction in experimental perilymph fistulas. Laryngoscope. 1991;101:1307-12 pubmed
  18. Dieterich M. Dizziness. Neurologist. 2004;10:154-64 pubmed
    ..The functional ranges of the systems overlap, thus permitting them to compensate in part for each other's deficiencies...
  19. Yanagihara N, Hyodo J, Takagi D, Miuchi S. A case of pneumolabyrinth induced by Eustachian tube air inflation. Otol Neurotol. 2012;33:1408-11 pubmed publisher
    ..Here, we report a case of pneumolabyrinth induced by Eustachian tube air inflation (ETAI) with a catheter and present evidence that multiple air bubbles entered the perilymphatic space through a preexisting oval window fistula...
  20. Rupa V, Agarwal I, Rajshekhar V. Congenital perilymph fistula causing recurrent meningitis: lessons learnt from a single-institution case series. Otolaryngol Head Neck Surg. 2014;150:285-91 pubmed publisher
    ..To study the steps involved in definitive evaluation and successful management of patients with congenital perilymph fistula presenting with recurrent meningitis...
  21. Meldrum J, Prinsley P. Perilymph fistula: the patients' experience. J Laryngol Otol. 2016;130:526-31 pubmed publisher
    ..This study aimed to assess the experiences and outcomes of patients who underwent surgical repair of a perilymph fistula in Norfolk, UK...
  22. Bruno E, Alessandrini M, Russo S, D Erme G, Nucci R. Perilymphatic fistula following trans-tympanic trauma: a clinical case presentation and review of the literature. An Otorrinolaringol Ibero Am. 2002;29:359-66 pubmed
    ..The peculiarity of this case must be set in relation with both the aetiopathogenesis of the labyrinthine lesion and the severity of the symptomatology caused by it...
  23. de Groot J, Veldman J. Early effects of gentamicin on inner ear glycocalyx cytochemistry. Hear Res. 1988;35:39-45 pubmed
    ..Cationized ferritin reactivity of the perilymphatic and endolymphatic glycocalyx was not significantly influenced. The cytochemistry of the inner ear glycocalyx and the possible biochemical changes induced by gentamicin are discussed...
  24. Rupa V, Rajshekhar V, Weider D. Syndrome of recurrent meninigitis due to congenital perilymph fistula with two different clinical presentations. Int J Pediatr Otorhinolaryngol. 2000;54:173-7 pubmed
    ..While one had a classical Mondini defect and unilateral hearing loss, the other had normal audiometric and radiographic findings. The fistulae were successfully closed via a tympanotomy approach in both the patients...
  25. Nakashima T, Watanabe Y, Yanagita N. The effect of round window membrane rupture on endolymphatic and perilymphatic pressures. Arch Otorhinolaryngol. 1987;244:236-40 pubmed
    ..these pressures: anoxia, hypercapnia, increased intracranial pressure, and occlusion of the vein of the cochlear aqueduct. When the round window membrane was not ruptured, increases in endolymphatic pressure paralleled the ..
  26. McGhee M, Dornhoffer J. A case of barotrauma-induced pneumolabyrinth secondary to perilymphatic fistula. Ear Nose Throat J. 2000;79:456-9 pubmed
    ..The niche was repaired with tragal perichondrium and bolstered with Gelfoam...
  27. Foster P, Luebke A. A model for perilymphatic fistula induced hearing loss in the guinea pig cochlea. Hear Res. 2002;167:175-9 pubmed
    ..In addition, the fluctuation of the hearing loss with positional changes supports the use of positional audiometry when evaluating perilymphatic fistulas...
  28. Albera R, Giordano L, Rosso P, Canale A, Cavalot A, Di Girolamo S, et al. Surgery of otosclerosis in the elderly. Aging (Milano). 2001;13:8-10 pubmed
    ..On the basis of the results obtained, it is concluded that stapes surgery should be offered to elderly patients with the same indications as younger patients with otosclerosis...
  29. Lesinski S. Causes of conductive hearing loss after stapedectomy or stapedotomy: a prospective study of 279 consecutive surgical revisions. Otol Neurotol. 2002;23:281-8 pubmed
    ..To analyze the causes for residual or recurrent conductive hearing loss following stapedectomy or stapedotomy and then propose surgical techniques to avoid these complications...
  30. Albera R, Cavalot A, Musto R, Fadda G, Staffieri A, Di Girolamo S. Tympanic membrane displacement analyser tracing modifications induced by glycerol in Menière's disease. Audiology. 2001;40:185-90 pubmed
    ..Since a Vi improvement implies a reduction of perilymph pressure, our results confirm the effectiveness of Vi in detecting specific action of glycerol in MD...
  31. Ciuman R. Communication routes between intracranial spaces and inner ear: function, pathophysiologic importance and relations with inner ear diseases. Am J Otolaryngol. 2009;30:193-202 pubmed publisher
    ..exist 3 communication routes between the intracranial space and the inner ear, the vestibular aqueduct, the cochlear aqueduct, and the internal auditory canal...
  32. Roehm P, Hoffer M, Balaban C. Gentamicin uptake in the chinchilla inner ear. Hear Res. 2007;230:43-52 pubmed
    ..Cell bodies in the ipsilateral dorsal cochlear nucleus bordering the cochlear aqueduct (CA) showed a lateral to medial gradient of gentamicin staining, suggesting the CA as a potential site of ..
  33. Mancini P, D Elia C, Bosco E, De Seta E, Panebianco V, Vergari V, et al. Follow-up of cochlear implant use in patients who developed bacterial meningitis following cochlear implantation. Laryngoscope. 2008;118:1467-71 pubmed publisher
    ..The present study is a long-term follow-up of speech perception outcomes and cochlear implant use in three cases of meningitis that occurred after cochlear implantation...
  34. Migirov L, Kronenberg J. Petromastoid canal and cochlear aqueduct in cochlear implant candidates. Otolaryngol Head Neck Surg. 2009;140:419-22 pubmed publisher
    ..To present temporal bone fine channels in cochlear implantation candidates...
  35. Wolters F, Klis S, Hamers F, de Groot J, Smoorenburg G. Perilymphatic application of alpha-melanocyte stimulating hormone ameliorates hearing loss caused by systemic administration of cisplatin. Hear Res. 2004;189:31-40 pubmed
    ..Since alpha-MSH was directly delivered to the cochlea, the ameliorating effect of alpha-MSH on OHC survival is likely to involve a cochlear target...
  36. Prisman E, Ramsden J, Blaser S, Papsin B. Traumatic perilymphatic fistula with pneumolabyrinth: diagnosis and management. Laryngoscope. 2011;121:856-9 pubmed publisher
    ..We suggest exploration be reserved for patients with persisting cerebrospinal fluid leakage, progressive sensorineural hearing loss, or vestibular symptomatology...
  37. Achache M, Sanjuan Puchol M, Santini L, Lafont B, Cihanek M, Lavieille J, et al. Late pneumolabyrinth after undiagnosed post-traumatic perilymphatic fistula. Case report illustrating the importance of systematic emergency management. Eur Ann Otorhinolaryngol Head Neck Dis. 2013;130:283-7 pubmed publisher
    ..Labyrinth involvement is rare, but there is a risk of perilymphatic rupture that is often underestimated on initial clinical examination due to the predominance of neurological and/or somatic symptoms...
  38. Magliulo G, Petti R, Vingolo G, Ronzoni R. [Experimental perilymphatic fistula: the electrocochleographic findings]. Acta Otorhinolaryngol Ital. 1992;12:547-52 pubmed
    ..This latter observation associated with a decrease in the amplitude of the threshold seems to be a specific audiologic sign of the fistula. The clinical implication are discussed...
  39. Kleemann D, Nofz S, Plank I, Schlottmann A. [Rupture of the round window--detection with fluorescence endoscopy]. HNO. 2001;49:89-92 pubmed
    ..Both patients obtained a normal hearing curve within 1 week after surgical intervention and obliteration of the round niche...
  40. Shupak A. Recurrent diving-related inner ear barotrauma. Otol Neurotol. 2006;27:1193-6 pubmed
    ..To present two cases of recurrent diving-related inner ear barotrauma (IEB) and to discuss the possible cause and pathogenesis of the increased inner ear vulnerability...
  41. Lollis S, Weider D, Phillips J, Roberts D. Ventriculoperitoneal shunt insertion for the treatment of refractory perilymphatic fistula. J Neurosurg. 2006;105:1-5 pubmed
    ..The goal of this study was to provide preliminary data regarding clinical and functional outcome, including postoperative morbidity, related to ventriculoperitoneal (VP) shunt insertion for refractory perilymphatic fistula...
  42. Thalen E, Wit H, Segenhout J, Albers F. Dynamics of inner ear pressure change caused by intracranial pressure manipulation in the guinea pig. Acta Otolaryngol. 2001;121:470-6 pubmed
    ..The main route for pressure transfer is the cochlear aqueduct. about which little is known with regard to its dynamic properties...
  43. Thalen E, Wit H, Segenhout H, Albers F. Inner ear pressure changes following square wave intracranial or ear canal pressure manipulation in the same guinea pig. Eur Arch Otorhinolaryngol. 2002;259:174-9 pubmed
    ..As expected, the combination of the cochlear aqueduct and the inner ear behaves as a low-pass filtering system for intracranial pressure manipulation and as a ..
  44. Reis H, Marques R, Moussalle S. [Perilymphatic fistula: report of a case which resolved spontaneously in five days and literature review]. Rev Neurol. 2002;34:838-40 pubmed
    ..We report a patient with a perilymphatic fistula and review the literature on this topic...
  45. Valk W, Wit H, Albers F. Effect of acute inner ear pressure changes on low-level distortion product otoacoustic emissions in the guinea pig. Acta Otolaryngol. 2004;124:929-36 pubmed
    ..To determine a relation between acute inner ear pressure changes and cochlear function as measured by low-level 2f(1)-f(2) distortion product otoacoustic emissions (DPOAEs)...
  46. Palmieri A, Ettorre G. Cochlear and vestibular acqueducts. Radiol Med. 2004;107:541-53; quiz 554-5 pubmed
  47. Krombach G, Schmitz Rode T, Prescher A, DiMartino E, Weidner J, Gunther R. The petromastoid canal on computed tomography. Eur Radiol. 2002;12:2770-5 pubmed
    ..diameter, obtained in the middle portion of the canal, was compared with the diameter of the vestibular and cochlear aqueduct in all patients, and absolute values measured in 20 cases...
  48. Bussières R, Portmann D, Noyon P. [When to suspect a perilymphatic fistula?]. Rev Laryngol Otol Rhinol (Bord). 2003;124:259-64 pubmed
    ..The diagnosis of perilymphatic fistula (PLF) is difficult since no single clinical situation gives the diagnosis for sure. The goal of this study is to clarify the clinical situations where you must suspect a PLF...
  49. Schroeder A, Darrow D. Management of the draining ear in children. Pediatr Ann. 2004;33:843-53 pubmed
    ..In such cases, prompt referral to the otolaryngologist can facilitate accurate diagnosis and successful management...
  50. Gopen Q, Rosowski J, Merchant S. Anatomy of the normal human cochlear aqueduct with functional implications. Hear Res. 1997;107:9-22 pubmed
    There is great variation in published descriptions of the shape, size, and patency of the human cochlear aqueduct. The first part of this paper describes the anatomy of the normal human cochlear aqueduct as determined from a study of 101 ..
  51. Stimmer H. Enlargement of the cochlear aqueduct: does it exist?. Eur Arch Otorhinolaryngol. 2011;268:1655-61 pubmed publisher
    Our intention was to evaluate whether enlargement of the cochlear aqueduct could play a role in dysfunctions of the inner ear...
  52. Böhmer A. Early alterations of cochlear function in experimental perilymph fistulas. Laryngoscope. 1990;100:389-94 pubmed
    ..A sudden (conductive) hearing loss and a poor response to suprathreshold stimulation might indicate inner ear damage secondary to a perilymphatic fistula...
  53. Foster P. Autologous intratympanic blood patch for presumed perilymphatic fistulas. J Laryngol Otol. 2016;130:1158-1161 pubmed
    ..To assess an alternative to bed rest and surgery for suspected perilymphatic fistulas using intratympanic blood injections...