methicillin resistance

Summary

Summary: Non-susceptibility of a microbe to the action of METHICILLIN, a semi-synthetic penicillin derivative.

Webpages

  1. morning report » hepatopulmonary syndrome
    www.hsls.pitt.edu/morningreport/?cat=269
  2. morning report » time
    www.hsls.pitt.edu/morningreport/?cat=165
  3. genomic research laboratory geneva - qmrsa: detection of mrsa
    www.genomic.ch/research_qmrsa.php
  4. morning report » endocarditis
    www.hsls.pitt.edu/morningreport/?cat=228
  5. mrsa hospitalizations, united states | cdc eid
    www.cdc.gov/ncidod/eid/vol11no06/04-0831.htm
  6. mary t. johnson, ph.d
    www.indstate.edu/thcme/johnson/
  7. quadruplets
    buchta.lib.bioinfo.pl/meid:64729
  8. the rockefeller university - alexander tomasz lab
    www.rockefeller.edu/labheads/tomasz/tomasz-lab.php
  9. methicillin-resistant staphylococcus aureus in human milk - materials and methods
    memorias.ioc.fiocruz.br/951/3824mm.html
  10. parker college of chiropractic
    www.parkercc.edu/ContentPrint.aspx?id=1249

Research Grants

  1. Analysis of VraSR and VraSR regulated gene expression in Staphylococcus aureus
    Radheshyam K Jayaswal; Fiscal Year: 2008
  2. PENICILLIN INTERACTIVE PROTEINS OF STAPHYLOCOCCUS AUREUS
    Henry F Chambers; Fiscal Year: 2003
  3. Staphylococcal methicillin resistance locus
    Gordon L Archer; Fiscal Year: 2008
  4. Staphylococcal methicillin resistance locus
    Gordon L Archer; Fiscal Year: 2007
  5. Horizontal Genetic Transfer In Straphylococi
    Ashley Robinson; Fiscal Year: 2008
  6. Proline uptake in staphylococcus aureus pathogenesis
    William R Schwan; Fiscal Year: 2002
  7. Horizontal Genetic Transfer In Straphylococi
    Ashley Robinson; Fiscal Year: 2007
  8. Applied Research on Antimicrobial Ressitance
    Daniel J Sexton; Fiscal Year: 2005
  9. Outcomes of and Risk factors for Infections due to USA300 MRSA
    Kristen M Kreisel; Fiscal Year: 2007
  10. Regulation/mecA gene expression/clinic S.aureus isolates
    Adriana E Rosato; Fiscal Year: 2005

Publications

  1. Update on emerging infections: news from the Centers for Disease Control and Prevention
    Gregory J Moran
    Department of Emergency Medicine, Olive View-UCLA Medical Center, Sylmar, CA, USA
    Ann Emerg Med 41:148-51
  2. Vancomycin intermediate and resistant Staphylococcus aureus. What the nephrologist needs to know
    L Clifford McDonald
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Nephrol News Issues 18:63-4, 66-7, 71-2 passim
  3. [Resistance to antibiotics of Staphylococcus aureus responsible of osteoarticular infections]
    J Raymond
    Université Renée Descartes, Service de Bactériologie, Hôpital Cochin, 27 r Fbg St Jacques 75014 Paris, France
    Arch Pediatr 14:S97-S101
  4. Virulence characteristics of community-associated Staphylococcus aureus and in vitro activities of moxifloxacin alone and in combination against community-associated and healthcare-associated meticillin-resistant and -susceptible S. aureus
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    J Med Microbiol 57:452-6
  5. Isolation in Brazil of nosocomial Staphylococcus aureus with reduced susceptibility to vancomycin
    G A Oliveira
    Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil
    Infect Control Hosp Epidemiol 22:443-8
  6. Staphylococcal cassette chromosome mec and Panton-Valentine leukocidin characterization of methicillin-resistant Staphylococcus aureus clones
    Shannon M Moroney
    Esoteric Testing, Department of Pathology, Tampa General Hospital, P O Box 1289, Tampa, Florida 33601, USA
    J Clin Microbiol 45:1019-21
  7. Methicillin-resistant versus methicillin-sensitive Staphylococcus aureus infective endocarditis
    E E Hill
    Department of Internal Medicine Infectious Diseases, K U Leuven, University Hospital Gasthuisberg, Leuven, Belgium
    Eur J Clin Microbiol Infect Dis 27:445-50
  8. Comparison of genetic backgrounds of methicillin-resistant and -susceptible Staphylococcus aureus isolates from Portuguese hospitals and the community
    M Aires de Sousa
    Laboratório de Genética Molecular, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal
    J Clin Microbiol 43:5150-7
  9. Transmission and epidemiology of MRSA: current perspectives
    Maggi Banning
    The School of Health and Social Sciences, Middlesex University, Archway Campus, London
    Br J Nurs 14:548-51, 554
  10. Molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream isolates in urban Detroit
    Thea Chua
    Henry Ford Health System, Wayne State University School of Medicine, Detroit, Michigan 48202, USA
    J Clin Microbiol 46:2345-52

Scientific Experts

Detail Information

Webpages16

  1. morning report » hepatopulmonary syndrome
    www.hsls.pitt.edu/morningreport/?cat=269
  2. morning report » time
    www.hsls.pitt.edu/morningreport/?cat=165
  3. genomic research laboratory geneva - qmrsa: detection of mrsa
    www.genomic.ch/research_qmrsa.php
  4. morning report » endocarditis
    www.hsls.pitt.edu/morningreport/?cat=228
  5. mrsa hospitalizations, united states | cdc eid
    www.cdc.gov/ncidod/eid/vol11no06/04-0831.htm
  6. mary t. johnson, ph.d
    www.indstate.edu/thcme/johnson/
  7. quadruplets
    buchta.lib.bioinfo.pl/meid:64729
  8. the rockefeller university - alexander tomasz lab
    www.rockefeller.edu/labheads/tomasz/tomasz-lab.php
  9. methicillin-resistant staphylococcus aureus in human milk - materials and methods
    memorias.ioc.fiocruz.br/951/3824mm.html
  10. parker college of chiropractic
    www.parkercc.edu/ContentPrint.aspx?id=1249
  11. oxazolidinones
    buchta.lib.bioinfo.pl/meid:183998
  12. fleming forum - infection, immunity and control
    flemingforum.org.uk/index.asp
  13. neutropenia
    lib.bioinfo.pl/meid:28748
  14. outcomerea: promotion et développement de l'enseignement et de la recherche en réanimation
    www.outcomerea.org/Publication/Is-methicillin-resistance-ass ...

Research Grants10

  1. Analysis of VraSR and VraSR regulated gene expression in Staphylococcus aureus
    Radheshyam K Jayaswal; Fiscal Year: 2008
    ..GISA strains, along with proteomic and genomic analyses to investigate the mechanisms of vancomycin/ methicillin resistance in S. aureus. Transcriptional profiling of S...
  2. PENICILLIN INTERACTIVE PROTEINS OF STAPHYLOCOCCUS AUREUS
    Henry F Chambers; Fiscal Year: 2003
    ..The objective of this research is to further knowledge of mechanisms of methicillin resistance. Resistance is determined by several proteins that interact with penicillin...
  3. Staphylococcal methicillin resistance locus
    Gordon L Archer; Fiscal Year: 2008
    ..In addition, microarray and proteomic studies will be pursued on other agents that perturb the cell wall. Public Health Relevance: This Public Health Relevance is not available...
  4. Staphylococcal methicillin resistance locus
    Gordon L Archer; Fiscal Year: 2007
    ..The purine biosynthetic operons will be genetically manipulated and correlated with development of VR and OR. In addition, microarray and proteomic studies will be pursued on other agents that perturb the cell wall...
  5. Horizontal Genetic Transfer In Straphylococi
    Ashley Robinson; Fiscal Year: 2008
    ..The accessory genetic element, SCCmec, harbors the methicillin resistance determinant and is thought to be horizontally transferred between the principal staphylococcal pathogen, ..
  6. Proline uptake in staphylococcus aureus pathogenesis
    William R Schwan; Fiscal Year: 2002
    ..Recent outbreaks of community-acquired S. aureus possessing methicillin resistance and the emergence of vancomycin-resistant S...
  7. Horizontal Genetic Transfer In Straphylococi
    Ashley Robinson; Fiscal Year: 2007
    ..The accessory genetic element, SCCmec, harbors the methicillin resistance determinant and is thought to be horizontally transferred between the principal staphylococcal pathogen, ..
  8. Applied Research on Antimicrobial Ressitance
    Daniel J Sexton; Fiscal Year: 2005
    ..Specific aims: i) To define the attributable impact of methicillin resistance upon economic costs of surgical site infections and bloodstream infections due to S. aureus...
  9. Outcomes of and Risk factors for Infections due to USA300 MRSA
    Kristen M Kreisel; Fiscal Year: 2007
    ..Antibiotic resistance is common in S. aureus, of which methicillin resistance is the resistance of greatest clinical consequence. Infections due to methicillin-resistant S...
  10. Regulation/mecA gene expression/clinic S.aureus isolates
    Adriana E Rosato; Fiscal Year: 2005
    ..provide evidence of the existence of additional loci involved in or required for inducible expression of methicillin resistance. These data will provide valuable structure/function information to complement studies investigating the ..

Publications62

  1. Update on emerging infections: news from the Centers for Disease Control and Prevention
    Gregory J Moran
    Department of Emergency Medicine, Olive View-UCLA Medical Center, Sylmar, CA, USA
    Ann Emerg Med 41:148-51
  2. Vancomycin intermediate and resistant Staphylococcus aureus. What the nephrologist needs to know
    L Clifford McDonald
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Nephrol News Issues 18:63-4, 66-7, 71-2 passim
    ....
  3. [Resistance to antibiotics of Staphylococcus aureus responsible of osteoarticular infections]
    J Raymond
    Université Renée Descartes, Service de Bactériologie, Hôpital Cochin, 27 r Fbg St Jacques 75014 Paris, France
    Arch Pediatr 14:S97-S101
    ..It is now established that CA-MRSA are pathogens present all over the world. It thus became necessary to look after the epidemiology of these virulent strains...
  4. Virulence characteristics of community-associated Staphylococcus aureus and in vitro activities of moxifloxacin alone and in combination against community-associated and healthcare-associated meticillin-resistant and -susceptible S. aureus
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    J Med Microbiol 57:452-6
    ..The FICI values for doxycycline were 3-6 for 32/34 strains, indicating antagonism, suggesting that it should not be used in combination with moxifloxacin...
  5. Isolation in Brazil of nosocomial Staphylococcus aureus with reduced susceptibility to vancomycin
    G A Oliveira
    Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil
    Infect Control Hosp Epidemiol 22:443-8
    ..This alerts us to the possibility that VRSA may be capable of nosocomial transfer if adequate hospital infection control measures are not taken...
  6. Staphylococcal cassette chromosome mec and Panton-Valentine leukocidin characterization of methicillin-resistant Staphylococcus aureus clones
    Shannon M Moroney
    Esoteric Testing, Department of Pathology, Tampa General Hospital, P O Box 1289, Tampa, Florida 33601, USA
    J Clin Microbiol 45:1019-21
    ..CA-MRSA isolates carried the SCCmec type IV complex, and most were PVL positive. The HA-MRSA isolates carried the SCCmec type II complex and did not harbor the PVL genes...
  7. Methicillin-resistant versus methicillin-sensitive Staphylococcus aureus infective endocarditis
    E E Hill
    Department of Internal Medicine Infectious Diseases, K U Leuven, University Hospital Gasthuisberg, Leuven, Belgium
    Eur J Clin Microbiol Infect Dis 27:445-50
    ..Denial of surgery because of local or general factors in patients that meet criteria for surgical intervention in acute IE is prognostically ominous...
  8. Comparison of genetic backgrounds of methicillin-resistant and -susceptible Staphylococcus aureus isolates from Portuguese hospitals and the community
    M Aires de Sousa
    Laboratório de Genética Molecular, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal
    J Clin Microbiol 43:5150-7
    ..Furthermore, we provide evidence that the introduction of SCCmec into sensitive clones is most likely a relatively infrequent event that seems to depend not exclusively on the presence of a successful MSSA lineage...
  9. Transmission and epidemiology of MRSA: current perspectives
    Maggi Banning
    The School of Health and Social Sciences, Middlesex University, Archway Campus, London
    Br J Nurs 14:548-51, 554
    ....
  10. Molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream isolates in urban Detroit
    Thea Chua
    Henry Ford Health System, Wayne State University School of Medicine, Detroit, Michigan 48202, USA
    J Clin Microbiol 46:2345-52
    ..Infection control measures should focus not only on prevention of the spread of community strains in the hospital but also prevention of the spread of hospital strains associated with VRSA into the community...
  11. Methicillin-resistant Staphylococcus aureus in horses and horse personnel
    J Scott Weese
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada N1G 2W1
    Vet Clin North Am Equine Pract 20:601-13
    ..This statement was directed at control of MRSA in people; however, it is equally relevant in the veterinary context and should receive strong consideration...
  12. [The Dutch MRSA policy should be retained]
    B J M Vlaminckx
    Universitair Medisch Centrum Utrecht
    Ned Tijdschr Geneeskd 150:1884
    ..In addition, widespread use of vancomycin for treating MRSA infections encourages the spread and development of vancomycin-resistant micro-organisms...
  13. Differential growth of epidemic methicillin-resistant Staphylococcus aureus in vancomycin
    I Alshami
    Department of Medical Microbiology, Clinical Sciences Building 1, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK
    Br J Biomed Sci 62:109-13
    ..EMRSAs 1A, 2A and 15A became more resistant to methicillin, and EMRSAs 8A, 11A and 12A became less resistant to methicillin. These results suggest that more than one mechanism is responsible for this phenomenon...
  14. An analysis of a community-acquired pathogen in a Kentucky community: methicillin-resistant Staphylococcus aureus
    Forest W Arnold
    University of Louisville School of Medicine, KY 40292, USA
    J Ky Med Assoc 103:206-10
    ..After incision and drainage, a review of the antimicrobial sensitivities indicates that oral treatment may be adequate for a selection of cases...
  15. Intermediate vancomycin susceptibility in a community-associated MRSA clone
    Christopher J Graber
    Division of Infectious Diseases, University of California, San Francisco General Hospital, 94110, USA
    Emerg Infect Dis 13:491-3
    ..The strain was isolated from the bone of a 56-year-old man with lumbar osteomyelitis after a 6-week treatment course of vancomycin for catheter-associated septic thrombophlebitis...
  16. Staphylococcus aureus carrier state among elderly residents of a long-term care facility
    Gad Mendelson
    Shoham Geriatric Center, Pardes Hanna, Israel
    J Am Med Dir Assoc 4:125-7
    ..This information and the identification of factors associated with MRSA infection permit the development of an institutional infection control program...
  17. Beyond MRSA: VISA and VRSA: what will ward off these pathogens in health care facilities?
    Betsy Todd
    New York-Presbyterian Hospital, Columbia University Medical Center, New York City, NY, USA
    Am J Nurs 106:28-30
  18. Three-year survey of community-acquired methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin in a French university hospital
    T Naas
    Service de Bactériologie virologie hygiène, Hôpital de Bicêtre, Assistance Publique, Hôpitaux de Paris, Faculté de Médecine Paris Sud, Le Kremlin Bicêtre, France
    J Hosp Infect 61:321-9
    ..The incidence at Bicêtre Hospital was 0.8% of all S. aureus and 2% of all MRSA isolated. Our data indicate that these MRSA isolates might become hospital acquired...
  19. The emergence and importation of diverse genotypes of methicillin-resistant Staphylococcus aureus (MRSA) harboring the Panton-Valentine leukocidin gene (pvl) reveal that pvl is a poor marker for community-acquired MRSA strains in Ireland
    Angela S Rossney
    National MRSA Reference Laboratory, St James s Hospital, James s St, Dublin 8, Ireland
    J Clin Microbiol 45:2554-63
    ..3, and the remaining 11 isolates could not be subtyped. This study demonstrates that pvl is not a reliable marker for CA-MRSA in Ireland and reveals the emergence and importation of diverse genotypes of pvl-positive MRSA in Ireland...
  20. Sporadic "transitional" community-associated methicillin-resistant Staphylococcus aureus strains from health care facilities in the United States
    Jennifer M Brady
    Molecular Microbiology Laboratory, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
    J Clin Microbiol 45:2654-61
    ..The potential role of PVL-carrying phages and plasmids in the success of CA-MRSA clones has been discussed...
  21. Comparisons of community-associated methicillin-resistant Staphylococcus aureus (MRSA) and hospital-associated MSRA infections in Sacramento, California
    Hsin Huang
    Department of Infectious Disease, University of California, Davis, Medical Center, 4150 V Street, PSSB, G500, Sacramento, CA 95817, USA
    J Clin Microbiol 44:2423-7
    ..This strain originated in the community and is not related to MRSA strains from healthcare settings. Injecting drug users could be a major reservoir for CA-MRSA transmission...
  22. Emergence of community-associated methicillin-resistant Staphylococcus aureus USA 300 clone as a cause of health care-associated infections among patients with prosthetic joint infections
    Ekaterina V Kourbatova
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
    Am J Infect Control 33:385-91
    ..CONCLUSION: We have demonstrated that the CA-MRSA USA300 clone is no longer just a cause of community-acquired infections but has also emerged as a cause of health care-associated infections, causing PJI at our institution...
  23. Resistance to methicillin and other antimicrobials among community-acquired and nosocomial Staphylococcus aureus strains in a pediatric teaching hospital in Salvador, Northeast Brazil
    Cristiana M Nascimento Carvalho
    Department of Pediatrics, School of Medicine, Federal University of Bahia UFBA, Salvador, Bahia, Brazil
    Microb Drug Resist 14:129-31
    ..9% vs. 4.9%, p<0.001). Resistance to other antimicrobials was more common among NI-MRSA compared with CA-MRSA. Although at a low rate, CA-MRSA has occurred among children, in this region...
  24. Comparison of community-acquired methicillin-resistant Staphylococcus aureus bacteremia to other staphylococcal species in a neonatal intensive care unit
    Jacob Kuint
    Neonatal Department, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Pediatr 166:319-25
    ..One possible explanation for this observation is that the CA-MRSA outbreak strain did not contain the pvl-gene, which has been suggested to be a significant virulence factor...
  25. Community- and health care-associated methicillin-resistant Staphylococcus aureus: a comparison of molecular epidemiology and antimicrobial activities of various agents
    Brian T Tsuji
    Anti Infective Research Laboratory, Department of Pharmacy Practice, Wayne State University, MI 48201, USA
    Diagn Microbiol Infect Dis 58:41-7
    ..Further studies are warranted against a larger number of molecularly defined, geographically diverse CAMRSA to confirm these findings...
  26. Community-acquired methicillin-resistant Staphylococcus aureus in children in northern Taiwan
    Yin-Hua Fang
    Department of Pediatrics, Min-Sheng General Hospital, Taoyuan, Taiwan, ROC
    J Microbiol Immunol Infect 37:29-34
    ..Our data suggest an increasing role of MRSA as a community pathogen in previously healthy children. Infection control strategies for both hospital and community should be re-evaluated...
  27. Molecular epidemiology of community- and health care-associated methicillin-resistant Staphylococcus aureus in Manitoba, Canada
    John L Wylie
    Cadham Provincial Public Health Laboratory, Manitoba Health, P O Box 8450, 750 William Ave, Winnipeg, Manitoba, R3C 3Y1
    J Clin Microbiol 43:2830-6
    ..Mapping of specific CA-MRSA types over successive 5-year periods showed rapid temporal shifts in prevalence in different parts of the province...
  28. Are community-associated methicillin-resistant Staphylococcus aureus (MRSA) strains replacing traditional nosocomial MRSA strains?
    Kyle J Popovich
    Division of Infectious Disease, Department of Medicine, Rush University Medical Center, and Division of Infectious Disease, Department of Medicine, Stroger Hospital of Cook County, Chicago, Illinois 60612, USA
    Clin Infect Dis 46:787-94
    ..For most risk factors and outcomes, patients infected with CG and HG strains were similar, suggesting that, thus far, CG strains are behaving like their traditional hospital-associated counterparts...
  29. Hospital transmission of community-acquired methicillin-resistant Staphylococcus aureus among postpartum women
    Lisa Saiman
    Department of Pediatrics, Columbia University, New York, New York 10032, USA
    Clin Infect Dis 37:1313-9
    ..We report that MW2, which was previously limited to the midwestern United States, has spread to the northeastern United States and has become a health care-associated pathogen...
  30. Spread of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) in hospitals in Taipei, Taiwan in 2005, and comparison of its drug resistance with previous hospital-acquired MRSA
    Tomomi Takano
    Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan, and National Taiwan University Hospital, Taipei, Taiwan
    Microbiol Immunol 51:627-32
    ..The data suggests that although PVL+ CA-MRSA is isolated at a high incidence from hospitals in Taipei, the drug resistance is mostly selected in the community and less prominent compared with previous PVL- hospital-acquired MRSA...
  31. Prevalence of inducible clindamycin resistance among community- and hospital-associated Staphylococcus aureus isolates
    Mukesh Patel
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
    J Clin Microbiol 44:2481-4
    ..Due to the low prevalence of MLSBi among CA-MRSA isolates, clindamycin remains a useful option for outpatient therapy...
  32. Antimicrobial susceptibility and clonal relatedness between community- and hospital-acquired methicillin-resistant Staphylococcus aureus from blood cultures
    Sook In Jung
    Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Republic of Korea
    J Microbiol 44:336-43
    ..This study suggests that, although the CA-MRSA blood isolates showed diverse PFGE and antimicrobial resistance patterns, some of these isolates may have originated from the HA-MRSA strains...
  33. Epidemiology and typing of Staphylococcus aureus strains isolated from bloodstream infections
    Nathalie van der Mee Marquet
    Departement de Microbiologie et Moléculaire, UFR Médecine, Tours Cedex, France
    J Clin Microbiol 42:5650-7
    ....
  34. In vitro activity of daptomycin against multidrug-resistant Staphylococcus aureus and S. aureus with known virulence factors, including community-acquired methicillin-resistant isolates
    Diane M Anastasiou
    Cubist Pharmaceuticals Inc, Lexington, MA 02421, USA
    Diagn Microbiol Infect Dis 61:339-42
    ..aureus with known virulence genes. All isolates were inhibited at <or=1 microg/mL, suggesting that daptomycin has excellent activity against both hospital-acquired and community-acquired S. aureus isolates...
  35. [Methicillin-resistant Staphylococcus aureus (MRSA) in the community]
    A G Vonk
    VU Medisch Centrum, afd Medische Microbiologie en Infectiepreventie, Postbus 7057, 1007 MB, Amsterdam
    Ned Tijdschr Geneeskd 151:401-7
    ..In order to prevent and control CA-MRSA outbreaks in the community successfully, the restrictive Dutch antibiotic policy must be followed with strict infection prevention measures...
  36. Bactericidal activity of orally available agents against methicillin-resistant Staphylococcus aureus
    Anjum S Kaka
    Section of Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    J Antimicrob Chemother 58:680-3
    ..No differences in bactericidal activity were detected when activities against CA-MRSA and HA-MRSA were compared...
  37. Antimicrobial susceptibility and staphylococcal chromosomal cassette mec type in community- and hospital-associated methicillin-resistant Staphylococcus aureus
    Kerry L LaPlante
    Anti Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, USA
    Pharmacotherapy 27:3-10
    ....
  38. A useful clinical approach to community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections
    B A Cunha
    J Hosp Infect 68:271-3
  39. Staphylococcus aureus: the new adventures of a legendary pathogen
    Susan J Rehm
    Department of Infectious Disease, Cleveland Clinic Foundation, OH 44195, USA
    Cleve Clin J Med 75:177-80, 183-6, 190-2
    ..Another worrisome trend is increasing resistance to vancomycin (Vancocin)...
  40. The community prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in older people living in their own homes: implications for treatment, screening and surveillance in the UK
    J Maudsley
    Academic Department Geriatric Medicine, Royal Free Campus, Royal Free and University College Medical School, Rowland Hill Street, Hampstead, London NW4 1AJ, UK
    J Hosp Infect 57:258-62
    ..Community antibiotic policies for skin and soft-tissue infection do not require amendment. Patients with previous MRSA should be isolated and screened on admission especially to high-risk units...
  41. Community-acquired methicillin-resistant Staphylococcus aureus in institutionalized adults with developmental disabilities
    Abraham Borer
    Soroka University Medical Center and the Ben-Gurion University of the Negev, Beer-Sheva, Isreal
    Emerg Infect Dis 8:966-70
    ..Selective antibiotic pressure may result in the emergence, persistence, and dissemination of MRSA strains, causing prolonged disease...
  42. Community-acquired methicillin-resistant Staphylococcus aureus: an ever-emerging epidemic
    Michael R Bubacz
    Wisconsin Department of Corrections, Madison, USA
    AAOHN J 55:193-4
    ..Prevention of MRSA infections can best be achieved by hand hygiene. Antibiotics should be chosen on the basis of culture results and sensitivity...
  43. Characterisation of non-multiresistant methicillin-resistant Staphylococcus aureus (including EMRSA-15) in Kuwait Hospitals
    E E Udo
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    Clin Microbiol Infect 12:262-9
    ..9%) isolates produced urease. These isolates were mainly from wound and skin infections, showed low-level methicillin resistance (MIC 8-48 mg/L), and nine carried genes for PVL...
  44. Susceptibilities to antiseptic agents and distribution of antiseptic-resistance genes qacA/B and smr of methicillin-resistant Staphylococcus aureus isolated in Asia during 1998 and 1999
    Norihisa Noguchi
    Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo 192 0392, Japan
    J Med Microbiol 54:557-65
    ....
  45. Analysis of meticillin-susceptible and meticillin-resistant biofilm-forming Staphylococcus aureus from catheter infections isolated in a large Italian hospital
    Dezemona Petrelli
    Department of Molecular, Cellular and Animal Biology, University of Camerino, Camerino, Italy
    J Med Microbiol 57:364-72
    ..These observations suggest that, at the local level and at a particular site of infection, S. aureus may show great genetic variability and escape the general rule of expansion of the S. aureus pandemic clones...
  46. Why tackling MRSA needs a comprehensive approach
    Sarah J Fairclough
    Epsom and St Helier University Hospitals NHS Trust, London
    Br J Nurs 15:72-5
    ..However, a comprehensive approach, including, in particular, good hand hygiene, could reduce the morbidity and mortality arising from MRSA and other hospital-acquired infections...
  47. The prevalence of methicillin-resistant Staphylococcus aureus
    Manuel Cortazal
    Am J Infect Control 34:613-5
  48. [Stakes, treatment strategies and progression of MRSA nosocomial pneumonia, especially pneumonia due to mechanical ventilation]
    R G Wunderink
    Methodist Healthcare, University of Tennessee, Memphis, USA
    Presse Med 33:2S5-9
    ..BETWEEN EFFICACY AND TOLERANCE: The increase in the MIC of vancomycin in the serum and the lungs during acute MRSA acquired under mechanical ventilation may provoke problems in tolerance, notably renal...
  49. Prevention of health care-associated methicillin-resistant Staphylococcus aureus infections: adapting to a changing epidemiology
    Tobi B Karchmer
    Clin Infect Dis 41:167-9
  50. Comparative in vitro activity of quinupristin/dalfopristin and seven other antimicrobials against methicillin-susceptible and methicillin-resistant nosocomial Staphylococcus aureus bloodstream isolates
    P Nikolaidis
    First Department of Internal Medicine, Infectious Diseases Division, University Hospital AHEPA, Thessaloniki, Greece
    J Chemother 14:544-6
    ..5mg/L. According to these results, quinupristin-dalfopristin shows promising in-vitro activity and may be a welcome alternative treatment for methicillin-resistant staphylococcal infections, resulting in reduced use of glycopeptides...
  51. [Nosocomial methicillin-resistant staphylococci that remain sensitive to non-beta lactam antibiotics]
    Roberto Manfredi
    Recenti Prog Med 94:344
  52. Frequency of mecA gene and borderline oxacillin resistant Staphylococcus aureus in nosocomial acquired methicillin resistance Staphylococcus aureus infections
    F Khorvash
    Isfahan University of Medical Sciences, Hezar Jerib Street, Isfahan, Iran
    Pak J Biol Sci 11:1282-5
    ..in our hospital, vancomycin should be reserved only for life threatening infections due to these organisms. Thus MRSA typing should be done to choose appropriate antibiotic for optimal treatment of MRSA infections...
  53. Arresting drug-resistant organisms
    Rebecca Kjonegaard
    Sharp Grossmont Hospital, La Mesa, CA, USA
    Nursing 35:48-50
  54. Pulse-field gel electrophoresis typing of methicillin-resistant Staphylococcus aureus strains susceptible to aminoglycosides isolated from 1993 to 2002
    M Lescat
    Laboratoire de Microbiologie, Hôpital Albert Chenevier, 40 rue de Mesly, 94000 Creteil, France
    J Hosp Infect 57:253-7
    ..This work indicates the need for further studies on the genome, to determine whether AS-MRSA have derived from strains that occurred before aminoglycosides came into clinical use...
  55. Costs associated with a strict policy to eradicate methicillin-resistant Staphylococcus aureus in a Dutch University Medical Center: a 10-year survey
    M Vriens
    Department of Surgery, University Medical Center Utrecht, HP G 04.228, Heidelberglaan 100, The Netherlands
    Eur J Clin Microbiol Infect Dis 21:782-6
    ....
  56. Useful oldies: oral antibiotics for the treatment of MRSA infections
    K Zvethkova
    J Hosp Infect 57:348-9
  57. Infection control or formulary control: what is the best tool to reduce nosocomial infections due to methicillin-resistant Staphylococcus aureus?
    Bala Hota
    Clin Infect Dis 42:785-7
  58. Identification of a variant "Rome clone" of methicillin-resistant Staphylococcus aureus with decreased susceptibility to vancomycin, responsible for an outbreak in an intensive care unit
    Marco Cassone
    Department of Clinical Medicine, University La Sapienza, Rome, Italy
    Microb Drug Resist 10:43-9
    ....
  59. Oral antibiotic treatment of MRSA infections
    B A Cunha
    J Hosp Infect 60:88-90
  60. Health care-associated endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin
    Chia Yu Chi
    Division of Clinical Research, National Health Research Institutes, Tainan, Taiwan
    J Clin Microbiol 46:810-3
    ..We report the successful treatment of a pediatric patient with SARV IE and characterization of the infecting strain. The MIC of vancomycin rose from 1.5 to 2 microg/ml, and the SARV was confirmed by population analysis...