Summary: A natural association between organisms that is detrimental to at least one of them. This often refers to the production of chemicals by one microorganism that is harmful to another.

Top Publications

  1. Zhu L, Reese J, Louis J, Campbell L, Chen M. Electrical penetration graph analysis of the feeding behavior of soybean aphids on soybean cultivars with antibiosis. J Econ Entomol. 2011;104:2068-72 pubmed
    ..Our study suggests that resistance factors exist in the phloem of the resistant soybean lines, and that these lines may contain antixenosis in addition to antibiosis.
  2. Lahlali R, Peng G, Gossen B, McGregor L, Yu F, Hynes R, et al. Evidence that the biofungicide Serenade (Bacillus subtilis) suppresses clubroot on canola via antibiosis and induced host resistance. Phytopathology. 2013;103:245-54 pubmed publisher
    ..It is possible that antibiosis and induced resistance are involved in clubroot suppression by Serenade...
  3. Russell A, Singh P, Brittnacher M, Bui N, Hood R, Carl M, et al. A widespread bacterial type VI secretion effector superfamily identified using a heuristic approach. Cell Host Microbe. 2012;11:538-49 pubmed publisher
  4. Rodrigues da Cunha L, Fortes Ferreira C, Durmaz E, Goh Y, Sanozky Dawes R, Klaenhammer T. Characterization of Lactobacillus gasseri isolates from a breast-fed infant. Gut Microbes. 2012;3:15-24 pubmed publisher
    ..This study identified and characterized recently isolated L. gasseri strains from faeces of a breast fed infant as potential probiotic candidates for use in the human milk banks in Brazil. ..
  5. Michelsen C, Stougaard P. Hydrogen cyanide synthesis and antifungal activity of the biocontrol strain Pseudomonas fluorescens In5 from Greenland is highly dependent on growth medium. Can J Microbiol. 2012;58:381-90 pubmed publisher
    ..These experiments strongly indicate that the synthesis of HCN is highly dependent on the growth medium used...
  6. Rancès E, Ye Y, Woolfit M, McGraw E, O Neill S. The relative importance of innate immune priming in Wolbachia-mediated dengue interference. PLoS Pathog. 2012;8:e1002548 pubmed publisher
  7. Dwidar M, Monnappa A, Mitchell R. The dual probiotic and antibiotic nature of Bdellovibrio bacteriovorus. BMB Rep. 2012;45:71-8 pubmed publisher
    ..Owing to the unique and dual nature of this bacterium, this review proposes the use of "amphibiotic" to describe these bacteria and their activities...
  8. Huebner C, Ding Y, Petermann I, Knapp C, Ferguson L. The probiotic Escherichia coli Nissle 1917 reduces pathogen invasion and modulates cytokine expression in Caco-2 cells infected with Crohn's disease-associated E. coli LF82. Appl Environ Microbiol. 2011;77:2541-4 pubmed publisher
    ..In this report, we investigate the potential of the probiotic Escherichia coli Nissle 1917 (EcN) to reduce features associated with AIEC pathogenicity in an already established infection with AIEC reference strain LF82. ..
  9. Tan H, Deng Z, Cao L. Isolation and characterization of actinomycetes from healthy goat faeces. Lett Appl Microbiol. 2009;49:248-53 pubmed publisher
    ..To isolate and characterize actinomycetes with probiotic activities from healthy goat faeces...

More Information


  1. Marshall K, Shakya S, Greenhill A, Padill G, Baker A, Warner J. Antibiosis of Burkholderia ubonensis againist Burkholderia pseudomallei, the causative agent for melioidosis. Southeast Asian J Trop Med Public Health. 2010;41:904-12 pubmed
    ..Isolates of environmentally derived non-pseudomallei Burkholderia spp (n=16) were screened for antibiosis against 27 B. pseudomallei isolates. Three isolates subsequently identified as B...
  2. Losada L, Ajayi O, Frisvad J, Yu J, Nierman W. Effect of competition on the production and activity of secondary metabolites in Aspergillus species. Med Mycol. 2009;47 Suppl 1:S88-96 pubmed publisher
    ..These findings indicate that co-cultivation could be a very promising method for inducing and characterizing novel antifungal compounds produced by species of Aspergillus. ..
  3. O Brien J, Wright G. An ecological perspective of microbial secondary metabolism. Curr Opin Biotechnol. 2011;22:552-8 pubmed publisher
  4. Meng F, Han Y, Teng W, Li Y, Li W. QTL underlying the resistance to soybean aphid (Aphis glycines Matsumura) through isoflavone-mediated antibiosis in soybean cultivar 'Zhongdou 27'. Theor Appl Genet. 2011;123:1459-65 pubmed publisher
    ..However, none of them was via isoflavone-mediated antibiosis process...
  5. Ferreira C, Grześkowiak L, Collado M, Salminen S. In vitro evaluation of Lactobacillus gasseri strains of infant origin on adhesion and aggregation of specific pathogens. J Food Prot. 2011;74:1482-7 pubmed publisher
    ..difficile in the mucus model. This study demonstrates that the studied L. gasseri strains fulfill the basic adhesion and aggregation properties for probiotics and could be considered for potential future use in children. ..
  6. Louis J, Lorenc Kukula K, Singh V, Reese J, Jander G, Shah J. Antibiosis against the green peach aphid requires the Arabidopsis thaliana MYZUS PERSICAE-INDUCED LIPASE1 gene. Plant J. 2010;64:800-11 pubmed publisher
    ..These results indicate that MPL1 has an essential function in antibiosis against GPA...
  7. Louis J, Leung Q, Pegadaraju V, Reese J, Shah J. PAD4-dependent antibiosis contributes to the ssi2-conferred hyper-resistance to the green peach aphid. Mol Plant Microbe Interact. 2010;23:618-27 pubmed publisher
    ..Instead, hyper-resistance in the ssi2 mutant results from heightened antibiosis that curtails insect reproduction...
  8. Heindl H, Wiese J, Thiel V, Imhoff J. Phylogenetic diversity and antimicrobial activities of bryozoan-associated bacteria isolated from Mediterranean and Baltic Sea habitats. Syst Appl Microbiol. 2010;33:94-104 pubmed publisher
    ..A total of 340 associated bacteria were isolated, and 101 displayed antibiotic activities. While antibiosis was predominantly directed against Gram-positive test strains, 16S rRNA gene sequencing revealed affiliation of ..
  9. Qin H, Zhang Z, Hang X, Jiang Y. L. plantarum prevents enteroinvasive Escherichia coli-induced tight junction proteins changes in intestinal epithelial cells. BMC Microbiol. 2009;9:63 pubmed publisher
    ..L. plantarum exerted a protective effect against the damage to integrity of Caco-2 monolayer cells and the structure and distribution of TJ proteins by EIEC infection. ..
  10. Köhler T, Donner V, van Delden C. Lipopolysaccharide as shield and receptor for R-pyocin-mediated killing in Pseudomonas aeruginosa. J Bacteriol. 2010;192:1921-8 pubmed publisher
    ..The results of this study highlight the potential role of R-pyocins in shaping bacterial populations during host colonization and support use of these molecules as specific and potent bactericidal agents. ..
  11. Hibbing M, Fuqua C, Parsek M, Peterson S. Bacterial competition: surviving and thriving in the microbial jungle. Nat Rev Microbiol. 2010;8:15-25 pubmed publisher
    ..The next challenge is to integrate the findings of these laboratory and theoretical studies and to evaluate the predictions that they generate in more natural settings. ..
  12. Garbeva P, Silby M, Raaijmakers J, Levy S, Boer W. Transcriptional and antagonistic responses of Pseudomonas fluorescens Pf0-1 to phylogenetically different bacterial competitors. ISME J. 2011;5:973-85 pubmed publisher
  13. Simark Mattsson C, Jonsson R, Emilson C, Roos K. Final pH affects the interference capacity of naturally occurring oral Lactobacillus strains against mutans streptococci. Arch Oral Biol. 2009;54:602-7 pubmed publisher
    ..mutans. ..
  14. Lim S, Im D. Screening and characterization of probiotic lactic acid bacteria isolated from Korean fermented foods. J Microbiol Biotechnol. 2009;19:178-86 pubmed
    ..aureus resulted most likely from both organic acids and bacteriocin. Based on its phenotypic characteristics and utilization of various sugars, the KC 21 strain was identified as Lactobacillus plantarum. ..
  15. Gião M, Azevedo N, Wilks S, Vieira M, Keevil C. Interaction of Legionella pneumophila and Helicobacter pylori with bacterial species isolated from drinking water biofilms. BMC Microbiol. 2011;11:57 pubmed publisher
    ..pneumophila but not the viability which indicates that the presence of autochthonous microorganisms can lead to misleading results when the safety of water is assessed by cultivable methods alone. ..
  16. Mela F, Fritsche K, de Boer W, van Veen J, De Graaff L, van den Berg M, et al. Dual transcriptional profiling of a bacterial/fungal confrontation: Collimonas fungivorans versus Aspergillus niger. ISME J. 2011;5:1494-504 pubmed publisher
    ..Both partners experienced nitrogen shortage in each other's presence. Overall, our results indicate that the Collimonas/Aspergillus interaction is a complex interplay between trophism, antibiosis and competition for nutrients.
  17. Romanenko L, Uchino M, Kalinovskaya N, Mikhailov V. Isolation, phylogenetic analysis and screening of marine mollusc-associated bacteria for antimicrobial, hemolytic and surface activities. Microbiol Res. 2008;163:633-44 pubmed
    ..The recovery of strains producing antimicrobial and surface-active substances suggests that microorganisms associated with the marine bivalve are potential source of bioactive metabolites. ..
  18. Zeriouh H, Romero D, Garcia Gutierrez L, Cazorla F, de Vicente A, Pérez García A. The iturin-like lipopeptides are essential components in the biological control arsenal of Bacillus subtilis against bacterial diseases of cucurbits. Mol Plant Microbe Interact. 2011;24:1540-52 pubmed publisher
    ..Taken together, our results highlight the potential of these B. subtilis strains as biocontrol agents against fungal and bacterial diseases of cucurbits and the versatility of iturins as antifungal and antibacterial compounds...
  19. Schierack P, Kleta S, Tedin K, Babila J, Oswald S, Oelschlaeger T, et al. E. coli Nissle 1917 Affects Salmonella adhesion to porcine intestinal epithelial cells. PLoS ONE. 2011;6:e14712 pubmed publisher
    ..This mechanism appears to be common to many E. coli strains, with strong adherence being a prerequisite for an effective reduction of SiiE-mediated Salmonella adhesion. ..
  20. Prieto P, Navarro Raya C, Valverde Corredor A, Amyotte S, Dobinson K, Mercado Blanco J. Colonization process of olive tissues by Verticillium dahliae and its in planta interaction with the biocontrol root endophyte Pseudomonas fluorescens PICF7. Microb Biotechnol. 2009;2:499-511 pubmed publisher
    ..dahliae is reported. Early and localized root surface and root endophytic colonization by P. fluorescens PICF7 is needed to impair full progress of verticillium wilt epidemics in olive. ..
  21. Kambris Z, Blagborough A, Pinto S, Blagrove M, Godfray H, Sinden R, et al. Wolbachia stimulates immune gene expression and inhibits plasmodium development in Anopheles gambiae. PLoS Pathog. 2010;6:e1001143 pubmed publisher
    ..The data are discussed with respect to the comparative effects on malaria vectorial capacity of life shortening and direct inhibition of Plasmodium development that can be produced by Wolbachia...
  22. Rae R, Iatsenko I, Witte H, Sommer R. A subset of naturally isolated Bacillus strains show extreme virulence to the free-living nematodes Caenorhabditis elegans and Pristionchus pacificus. Environ Microbiol. 2010;12:3007-21 pubmed publisher
    ..elegans and P. pacificus. Among 20 pathogenic strains with distinct virulence patterns against the two nematodes, we selected three B. cereus-like strains to investigate resistance and susceptibility immune responses in nematodes. ..
  23. Kong K, Schneper L, Mathee K. Beta-lactam antibiotics: from antibiosis to resistance and bacteriology. APMIS. 2010;118:1-36 pubmed publisher
    This review focuses on the era of antibiosis that led to a better understanding of bacterial morphology, in particular the cell wall component peptidoglycan...
  24. Lugtenberg B, Kamilova F. Plant-growth-promoting rhizobacteria. Annu Rev Microbiol. 2009;63:541-56 pubmed publisher
    ..Mechanisms of biological control by which rhizobacteria can promote plant growth indirectly, i.e., by reducing the level of disease, include antibiosis, induction of systemic resistance, and competition for nutrients and niches.
  25. Murdoch S, Trunk K, English G, Fritsch M, Pourkarimi E, Coulthurst S. The opportunistic pathogen Serratia marcescens utilizes type VI secretion to target bacterial competitors. J Bacteriol. 2011;193:6057-69 pubmed publisher
    ..marcescens with a very similar and active T6SS. We conclude that type VI secretion plays a crucial role in the competitiveness, and thus indirectly the virulence, of S. marcescens and other opportunistic bacterial pathogens. ..
  26. Saikia R, Gogoi D, Mazumder S, Yadav A, Sarma R, Bora T, et al. Brevibacillus laterosporus strain BPM3, a potential biocontrol agent isolated from a natural hot water spring of Assam, India. Microbiol Res. 2011;166:216-25 pubmed publisher
    ..The bacterium was characterized by morphological, biochemical and molecular approaches and confirmed that the strain BPM3 is Brevibacillus laterosporus. ..
  27. Arakawa K, Kawai Y, Iioka H, Tanioka M, Nishimura J, Kitazawa H, et al. Effects of gassericins A and T, bacteriocins produced by Lactobacillus gasseri, with glycine on custard cream preservation. J Dairy Sci. 2009;92:2365-72 pubmed publisher
    ..This is the first report showing the combined effect of bacteriocin and glycine and their application for food preservation, which may be helpful for future use in the food industry. ..
  28. Rypien K, Ward J, Azam F. Antagonistic interactions among coral-associated bacteria. Environ Microbiol. 2010;12:28-39 pubmed publisher
    ..Overall, this study demonstrates that antagonism could be a structuring force in coral-associated microbial communities and may contribute to pathogenesis as well as disease resistance. ..
  29. Pusey P, Stockwell V, Reardon C, Smits T, Duffy B. Antibiosis activity of Pantoea agglomerans biocontrol strain E325 against Erwinia amylovora on apple flower stigmas. Phytopathology. 2011;101:1234-41 pubmed publisher
    ..b>Antibiosis was evaluated as a mode of antagonism on flower stigmas using two antibiosis-deficient mutants...
  30. Ayeni F, Adeniyi B, Ogunbanwo S, Tabasco R, Paarup T, Peláez C, et al. Inhibition of uropathogens by lactic acid bacteria isolated from dairy foods and cow's intestine in western Nigeria. Arch Microbiol. 2009;191:639-48 pubmed publisher
    ..Based on their sensitivity to Weissella spp., there is a potential for using these LAB as a natural approach for the protection against the uropathogens assayed. ..
  31. Hahm M, Sumayo M, Hwang Y, Jeon S, Park S, Lee J, et al. Biological control and plant growth promoting capacity of rhizobacteria on pepper under greenhouse and field conditions. J Microbiol. 2012;50:380-5 pubmed publisher
    ..Collectively, the application of mixtures of PGPR strains on pepper might be considered as a potential biological control under greenhouse and field conditions. ..
  32. Müller T, Behrendt U, Ruppel S, von der Waydbrink G, Müller M. Fluorescent Pseudomonads in the Phyllosphere of Wheat: Potential Antagonists Against Fungal Phytopathogens. Curr Microbiol. 2016;72:383-9 pubmed publisher
    ..The results of the study suggest that pseudomonads in the phyllosphere of crop plants may possibly contribute to natural plant protection. ..
  33. Basurto Cadena M, Vázquez Arista M, García Jiménez J, Salcedo Hernandez R, Bideshi D, Barboza Corona J. Isolation of a new Mexican strain of Bacillus subtilis with antifungal and antibacterial activities. ScientificWorldJournal. 2012;2012:384978 pubmed publisher
    ..Chitinases and zwittermicin production could not be detected. Then, B. subtilis 21 could potentially be used to control phytopathogenic fungi that infect strawberry plants. ..
  34. do Nascimento M, de Almeida Sarmento R, Dos Santos G, de Oliveira C, de Souza D. Antagonism of Trichoderma isolates against Leucoagaricus gongylophorus (Singer) Möller. J Basic Microbiol. 2017;57:699-704 pubmed publisher
    ..gongylophorus. This isolate is a promising fungus for field tests of biological control methods for leaf-cutting ants. ..
  35. Zarate G, Palacios J, Villena J, Zúñiga Hansen M. Inhibition of enteropathogens adhesion to human enterocyte-like HT-29 cells by a dairy strain of Propionibacterium acidipropionici. Benef Microbes. 2016;7:431-41 pubmed publisher
    ..Enteritidis. Results suggest that P. acidipropionici Q4 could be considered for the development of propionibacteria containing functional foods helpful in counteracting enteropathogen infection. ..
  36. Cha J, Han S, Hong H, Cho H, Kim D, Kwon Y, et al. Microbial and biochemical basis of a Fusarium wilt-suppressive soil. ISME J. 2016;10:119-29 pubmed publisher
  37. Ho B, Basler M, Mekalanos J. Type 6 secretion system-mediated immunity to type 4 secretion system-mediated gene transfer. Science. 2013;342:250-3 pubmed publisher
    ..aeruginosa cells to potentially block acquisition of parasitic foreign DNA. ..
  38. Barberis C, Dalcero A, Magnoli C. Evaluation of aflatoxin B1 and ochratoxin A in interacting mixed cultures of Aspergillus sections Flavi and Nigri on peanut grains. Mycotoxin Res. 2012;28:149-56 pubmed publisher
    ..001). These results suggest that, under optimal environmental conditions in peanut grains, the interaction between A. flavus and A. niger aggregate strains could result in an inhibition of AFB1 and in a stimulation of OTA production. ..
  39. Sharafi H, Maleki H, Ahmadian G, Shahbani Zahiri H, Sajedinejad N, Houshmand B, et al. Antibacterial activity and probiotic potential of Lactobacillus plantarum HKN01: a new insight into the morphological changes of antibacterial compound-treated Escherichia coli by electron microscopy. J Microbiol Biotechnol. 2013;23:225-36 pubmed
    ..coli to the treatment with the antibacterial compound. According to the in vivo experiments oral administration of L. plantarum HKN01 resulted in recovery of infected BALB/c mice with Salmonella enterica ser. Typhimurium. ..
  40. Sanchez B, Urdaci M. Extracellular proteins from Lactobacillus plantarum BMCM12 prevent adhesion of enteropathogens to mucin. Curr Microbiol. 2012;64:592-6 pubmed publisher
    ..Extracellular proteins from BMCM12 reduced significantly the adhesion of the pathogens when they were added prior to adhesion assays. These proteins play thus important roles in preventing pathogen adhesion to the mucin layer. ..
  41. Wang M, Ma L, Han J, Liu H, He Y. [Identification of endophytic actinomycete St24 tomato plants from and its application in biocontrol of gray mold disease]. Ying Yong Sheng Tai Xue Bao. 2012;23:2529-35 pubmed
    ..cinerea. Foliar spraying the extracts at 100 mg x L(-1) had the best protective effect, with the controlling effect reached 94.3% after 24 h and 85.4% after 120 h. ..
  42. Delavenne E, Mounier J, Deniel F, Barbier G, Le Blay G. Biodiversity of antifungal lactic acid bacteria isolated from raw milk samples from cow, ewe and goat over one-year period. Int J Food Microbiol. 2012;155:185-90 pubmed publisher
    ..anomala. Raw milk, especially cow and goat milks from the summer/fall period appeared to be a productive reservoir for antifungal lactobacilli. ..
  43. Gueguen E, Cascales E. Promoter swapping unveils the role of the Citrobacter rodentium CTS1 type VI secretion system in interbacterial competition. Appl Environ Microbiol. 2013;79:32-8 pubmed publisher
    ..Artificial induction of both promoters demonstrated that the CTS1 T6SS is functional as shown by the Hcp release assay and confers on C. rodentium a growth advantage in antibacterial competition experiments with Escherichia coli. ..
  44. Puterka G, Scott J, Brown M, Hammon R. Response of Russian wheat aphid resistance in wheat and barley to four Diuraphis (Hemiptera: Aphididae) species. J Econ Entomol. 2013;106:1029-35 pubmed
    ..The Russian wheat aphid biotype 2 resistant wheat lines would be effective in managing both wheat pest species. ..
  45. Le Moal V, Fayol Messaoudi D, Servin A. Compound(s) secreted by Lactobacillus casei strain Shirota YIT9029 irreversibly and reversibly impair the swimming motility of Helicobacter pylori and Salmonella enterica serovar Typhimurium, respectively. Microbiology. 2013;159:1956-71 pubmed publisher
    ..The inhibition of S. Typhimurium SL1344 swimming motility leads to delayed cell entry into human enterocyte-like Caco-2/TC7 cells and a strong decrease of cell entry into human mucus-secreting HT29-MTX cells. ..
  46. Crowley S, Mahony J, Morrissey J, van Sinderen D. Transcriptomic and morphological profiling of Aspergillus fumigatus Af293 in response to antifungal activity produced by Lactobacillus plantarum 16. Microbiology. 2013;159:2014-24 pubmed publisher
    ..Increased transcription of the global regulator LaeA was also observed indicating that exposure to the antifungal activity caused a cellular stress response. ..
  47. Kinkel L, Schlatter D, Xiao K, Baines A. Sympatric inhibition and niche differentiation suggest alternative coevolutionary trajectories among Streptomycetes. ISME J. 2014;8:249-56 pubmed publisher
  48. Kapley A, Tanksale H, Sagarkar S, Prasad A, Kumar R, Sharma N, et al. Antimicrobial activity of Alcaligenes sp. HPC 1271 against multidrug resistant bacteria. Funct Integr Genomics. 2016;16:57-65 pubmed publisher
    ..Gene expression analysis demonstrated that both NRPS and dTDP-glucose 4,6-dehydratase gene clusters are functional and could be involved in antibacterial biosynthesis. ..
  49. Kergourlay G, Messaoudi S, Dousset X, Prevost H. Genome sequence of Lactobacillus salivarius SMXD51, a potential probiotic strain isolated from chicken cecum, showing anti-campylobacter activity. J Bacteriol. 2012;194:3008-9 pubmed publisher
  50. Youle M, Rohwer F, Stacy A, Whiteley M, Steel B, Delalez N, et al. The Microbial Olympics. Nat Rev Microbiol. 2012;10:583-8 pubmed publisher
    ..In this Essay, we honour the best competitors in the microbial world by inviting them to take part in the inaugural Microbial Olympics. ..
  51. Deng Y, Boon C, Chen S, Lim A, Zhang L. Cis-2-dodecenoic acid signal modulates virulence of Pseudomonas aeruginosa through interference with quorum sensing systems and T3SS. BMC Microbiol. 2013;13:231 pubmed publisher
    ..Treatment with BDSF obviously reduced the virulence of P. aeruginosa in both HeLa cell and zebrafish infection models. These results depict that BDSF modulates virulence of P. aeruginosa through interference with QS systems and T3SS. ..
  52. Pelinski R, Cerrutti P, Ponsone M, Chulze S, Galvagno M. Statistical optimization of simple culture conditions to produce biomass of an ochratoxigenic mould biocontrol yeast strain. Lett Appl Microbiol. 2012;54:377-82 pubmed publisher
    ..Cells of L. thermotolerans produced aerobically could be sustainably produced in a medium just containing cheap carbon, nitrogen and phosphorus sources. Response surface methodology allowed the fine-tuning of cultural conditions. ..
  53. Boughachiche F, Reghioua S, Zerizer H, Boulahrouf A. [Antibacterial activity of rare Streptomyces species against clinical resistant bacteria]. Ann Biol Clin (Paris). 2012;70:169-74 pubmed publisher
    ..It produces two types of bioactive molecules, one is polar and the second is non polar (according to thin layer chromatography technique results). ..