birth order

Summary

Summary: The sequence in which children are born into the family.

Top Publications

  1. Cardwell C, Stene L, Joner G, Cinek O, Svensson J, Goldacre M, et al. Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies. Diabetologia. 2008;51:726-35 pubmed publisher
    ..after Caesarean section was little altered after adjustment for gestational age, birth weight, maternal age, birth order, breast-feeding and maternal diabetes (adjusted OR 1.19, 95% CI 1.04-1.36, p = 0.01)...
  2. Singer H, Morris C, Gause C, Gillin P, Crawford S, Zimmerman A. Antibodies against fetal brain in sera of mothers with autistic children. J Neuroimmunol. 2008;194:165-72 pubmed
    ..Data support a possible complex association between genetic/metabolic/environmental factors and the placental transfer of maternal antibodies in autism. ..
  3. Kumar V, Jeyaseelan L, Sebastian T, Regi A, Mathew J, Jose R. New birth weight reference standards customised to birth order and sex of babies from South India. BMC Pregnancy Childbirth. 2013;13:38 pubmed publisher
    ..This study has addressed both the above issues and in addition provides birthweight reference ranges with regard to sex of the baby and maternal parity...
  4. Ochiai H, Shirasawa T, Ohtsu T, Nishimura R, Morimoto A, Obuchi R, et al. Number of siblings, birth order, and childhood overweight: a population-based cross-sectional study in Japan. BMC Public Health. 2012;12:766 pubmed publisher
    Although several studies have investigated the relationship between the number of siblings or birth order and childhood overweight, the results are inconsistent...
  5. Kusunoki T, Mukaida K, Morimoto T, Sakuma M, Yasumi T, Nishikomori R, et al. Birth order effect on childhood food allergy. Pediatr Allergy Immunol. 2012;23:250-4 pubmed publisher
    Higher birth order is associated with a smaller risk of allergy (birth order effect)...
  6. Lawson D, Mace R. Siblings and childhood mental health: evidence for a later-born advantage. Soc Sci Med. 2010;70:2061-2069 pubmed publisher
    The social and health sciences have often emphasised the negative impacts of large sibship size and late birth order on childhood...
  7. Gaughran F, Blizard R, Mohan R, Zammit S, Owen M. Birth order and the severity of illness in schizophrenia. Psychiatry Res. 2007;150:205-10 pubmed
    ..The effect of birth order on (1) severity of the worst ever episode of illness; (2) deterioration from premorbid level of functioning; (3)..
  8. Celik Y, Younis M. Effects of antenatal care services on birthweight: importance of model specification and empirical procedure used in estimating the marginal productivity of health inputs. J Med Syst. 2007;31:197-204 pubmed
    ..The estimated functions indicate that antenatal care, woman's health status, and birth order are significant determinants in birthweight...
  9. Mensah F, Willett E, Simpson J, Smith A, Roman E. Birth order and sibship size: evaluation of the role of selection bias in a case-control study of non-Hodgkin's lymphoma. Am J Epidemiol. 2007;166:717-23 pubmed
    ..studies investigating associations between non-Hodgkin's lymphoma and familial characteristics, such as birth order and sibship size...

Scientific Experts

More Information

Publications62

  1. Jha P, Kesler M, Kumar R, Ram F, Ram U, Aleksandrowicz L, et al. Trends in selective abortions of girls in India: analysis of nationally representative birth histories from 1990 to 2005 and census data from 1991 to 2011. Lancet. 2011;377:1921-8 pubmed publisher
    ..We aimed to establish the trends in sex ratio by birth order from 1990 to 2005 with three nationally representative surveys and to quantify the totals of selective ..
  2. Ghosh J, Bandyopadhyay A. Income, birth order, siblings, and anthropometry. Hum Biol. 2006;78:733-41 pubmed
    ..of the present cross-sectional study was to examine the relationship and effect of monthly household income, birth order, and number of siblings on adult body dimensions, adiposity index, and body composition among adult Bengali ..
  3. Schagen S, Delemarre van de Waal H, Blanchard R, Cohen Kettenis P. Sibling sex ratio and birth order in early-onset gender dysphoric adolescents. Arch Sex Behav. 2012;41:541-9 pubmed publisher
    ..Sibling sex ratio refers to the ratio of brothers to sisters in the aggregate sibships of a group of probands. Birth order refers to the probands' position (e.g., first-born, middle-born, last-born) within their sibships...
  4. Gomez Gil E, Esteva I, Carrasco R, Almaraz M, Pasaro E, Salamero M, et al. Birth order and ratio of brothers to sisters in Spanish transsexuals. Arch Sex Behav. 2011;40:505-10 pubmed publisher
    ..Compared with the expected rates in the general population, birth order was significantly higher in both MF (Slater's Index = 0.59; Fraternal Index = 0.61; Sororal Index = 0...
  5. Blanchard R. Review and theory of handedness, birth order, and homosexuality in men. Laterality. 2008;13:51-70 pubmed
    ..This phenomenon has been called the fraternal birth order effect...
  6. Lammi N, Moltchanova E, Blomstedt P, Eriksson J, Taskinen O, Sarti C, et al. The effect of birth order and parental age on the risk of type 1 and 2 diabetes among young adults. Diabetologia. 2007;50:2433-8 pubmed
    The aim of this study was to examine the effects of birth order and parental age on the risk of type 1 and type 2 diabetes among Finnish individuals aged 15-39 years...
  7. Schmidt L, Kamper Jørgensen M, Schmiegelow K, Johansen C, Lahteenmaki P, Träger C, et al. Infectious exposure in the first years of life and risk of central nervous system tumours in children: analysis of birth order, childcare attendance and seasonality of birth. Br J Cancer. 2010;102:1670-5 pubmed publisher
    ..4 million children, we studied the association of birth order and seasonal variation of birth with subsequent risk for CNS tumours...
  8. Giagazoglou P, Kabitsis N, Kokaridas D, Zaragas C, Katartzi E, Kabitsis C. The movement assessment battery in Greek preschoolers: the impact of age, gender, birth order, and physical activity on motor outcome. Res Dev Disabil. 2011;32:2577-82 pubmed publisher
    ..The findings reinforce the need for the evaluation of motor performance in preschool-aged children, in order specific individual motor profiles to be established for optimizing and adapting early intervention programs. ..
  9. Smith G, Fleming K, White I. Birth order of twins and risk of perinatal death related to delivery in England, Northern Ireland, and Wales, 1994-2003: retrospective cohort study. BMJ. 2007;334:576 pubmed
    To determine the effect of birth order on the risk of perinatal death in twin pregnancies. Retrospective cohort study. England, Northern Ireland, and Wales, 1994-2003...
  10. Blaser M, Nomura A, Lee J, Stemmerman G, Perez Perez G. Early-life family structure and microbially induced cancer risk. PLoS Med. 2007;4:e7 pubmed
    ..pylori- if the H. pylori test is falsely negative), belonging to a large sibship or higher birth order was associated with a significantly increased risk of developing gastric adenocarcinoma late in life...
  11. Tatsuta N, Nakai K, Murata K, Suzuki K, Iwai Shimada M, Yaginuma Sakurai K, et al. Prenatal exposures to environmental chemicals and birth order as risk factors for child behavior problems. Environ Res. 2012;114:47-52 pubmed publisher
    ..disappeared when conducting multiple regression analysis with possible confounders; at that time, the birth order, home environment, and maternal intelligence quotient were significantly related to the internalizing score...
  12. Bogaert A. Biological versus nonbiological older brothers and men's sexual orientation. Proc Natl Acad Sci U S A. 2006;103:10771-4 pubmed
    ..consistent biodemographic correlate of sexual orientation in men is the number of older brothers (fraternal birth order). The mechanism underlying this effect remains unknown...
  13. VanderLaan D, Vasey P. Male sexual orientation in independent samoa: evidence for fraternal birth order and maternal fecundity effects. Arch Sex Behav. 2011;40:495-503 pubmed publisher
    ..e., the fraternal birth order effect)...
  14. Bogaert A, Skorska M. Sexual orientation, fraternal birth order, and the maternal immune hypothesis: a review. Front Neuroendocrinol. 2011;32:247-54 pubmed publisher
    ..This "fraternal birth order" (FBO) effect has been replicated numerous times, including in non-Western samples...
  15. Ramasamy A, Curjuric I, Coin L, Kumar A, McArdle W, Imboden M, et al. A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. J Allergy Clin Immunol. 2011;128:996-1005 pubmed publisher
    ..We found no evidence for variants that modified the effect of birth order on either phenotype...
  16. Cardwell C, Stene L, Joner G, Bulsara M, Cinek O, Rosenbauer J, et al. Birth order and childhood type 1 diabetes risk: a pooled analysis of 31 observational studies. Int J Epidemiol. 2011;40:363-74 pubmed publisher
    ..We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies...
  17. Turner T, Pihur V, Chakravarti A. Quantifying and modeling birth order effects in autism. PLoS ONE. 2011;6:e26418 pubmed publisher
    ..We analyzed the data from three publicly available autism family collections in the USA for potential birth order effects and studied the statistical properties of three tests to show that adequate power to detect these ..
  18. Jelenkovic A, Silventoinen K, Tynelius P, Myrskylä M, Rasmussen F. Association of birth order with cardiovascular disease risk factors in young adulthood: a study of one million Swedish men. PLoS ONE. 2013;8:e63361 pubmed publisher
    b>Birth order has been suggested to be linked to several cardiovascular disease (CVD) risk factors, but the evidence is still inconsistent...
  19. Ghaemmaghami S, Nikniaz L, Mahdavi R, Nikniaz Z, Razmifard F, Afsharnia F. Effects of infants' birth order, maternal age, and socio-economic status on birth weight. Saudi Med J. 2013;34:949-53 pubmed
    To determine the effects of infants' birth order, maternal age, and socioeconomic status (SES) on birth weight...
  20. Reichenberg A, Smith C, Schmeidler J, Silverman J. Birth order effects on autism symptom domains. Psychiatry Res. 2007;150:199-204 pubmed
    ..Nevertheless, the findings suggest that genetic studies in autism using specific levels of familial autism traits as phenotypes should take into account their intercorrelations and birth order effects embedded in the instrument.
  21. Becker N, de Sanjose S, Nieters A, Maynadie M, Foretova L, Cocco P, et al. Birth order, allergies and lymphoma risk: results of the European collaborative research project Epilymph. Leuk Res. 2007;31:1365-72 pubmed
    ..Our findings on birth order and lymphoma increase the inconsistency of findings across studies and suggest a critical reappraisal of ..
  22. Kristensen P, Bjerkedal T. Explaining the relation between birth order and intelligence. Science. 2007;316:1717 pubmed
    Negative associations between birth order and intelligence level have been found in numerous studies. The explanation for this relation is not clear, and several hypotheses have been suggested...
  23. Goldberg S, Israeli E, Schwartz S, Shochat T, Izbicki G, Toker Maimon O, et al. Asthma prevalence, family size, and birth order. Chest. 2007;131:1747-52 pubmed
    ..If the hygiene hypothesis is correct, asthma prevalence should be inversely related to birth order. The objective of this study was to examine the relationship between asthma prevalence, and family size and ..
  24. Wegienka G, Havstad S, Shue L, Zoratti E, Ownby D, Johnson C. Birth order and cord immunoglobulin E: results using a high-sensitivity immunoglobulin E protocol. Int Arch Allergy Immunol. 2008;145:305-12 pubmed
    Studies have shown an inverse association between birth order and allergic disease risk; some but not all have shown an inverse association between cord blood immunoglobulin E (IgE) and birth order...
  25. Blanchard R. Supplementary analyses regarding Langevin, Langevin, and Curnoe's (2007) findings on fraternal birth order in homosexual men. Arch Sex Behav. 2007;36:610-4; discussion 615-6 pubmed
    A recent article by Langevin, Langevin, and Curnoe (2007) reported mixed results regarding the fraternal birth order effect, that is, the repeatedly observed finding that older brothers correlate with homosexuality in later-born males...
  26. Langevin R, Langevin M, Curnoe S. Family size, birth order, and parental age among male paraphilics and sex offenders. Arch Sex Behav. 2007;36:599-609 pubmed
    A sample of 1823 male paraphilics, sex offenders, and non-sex offender controls were compared on family size, birth order, and parents' ages at the time of the probands' births...
  27. Schrader M, Travis J. Variation in offspring size with birth order in placental fish: a role for asymmetric sibling competition?. Evolution. 2012;66:272-9 pubmed publisher
    ..Together these results suggest that sibling competition is a direct consequence of the evolution of matrotrophy and superfetation in poeciliid fish. ..
  28. Cardwell C, Stene L, Joner G, Davis E, Cinek O, Rosenbauer J, et al. Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data. Diabetologia. 2010;53:641-51 pubmed publisher
    ..03 [95% CI 1.00-1.06]; p=0.03). Adjustments for potential confounders such as gestational age, maternal age, birth order, Caesarean section, breastfeeding and maternal diabetes had little effect on these findings...
  29. Ford A, Forman D, Bailey A, Goodman K, Axon A, Moayyedi P. Effect of sibling number in the household and birth order on prevalence of Helicobacter pylori: a cross-sectional study. Int J Epidemiol. 2007;36:1327-33 pubmed
    ..Effects of sibling number and birth order on prevalence of infection have not been extensively studied...
  30. Von Behren J, Spector L, Mueller B, Carozza S, Chow E, Fox E, et al. Birth order and risk of childhood cancer: a pooled analysis from five US States. Int J Cancer. 2011;128:2709-16 pubmed publisher
    The causes of childhood cancers are largely unknown. Birth order has been used as a proxy for prenatal and postnatal exposures, such as frequency of infections and in utero hormone exposures...
  31. Grulich A, Vajdic C, Falster M, Kane E, Smedby K, Bracci P, et al. Birth order and risk of non-hodgkin lymphoma--true association or bias?. Am J Epidemiol. 2010;172:621-30 pubmed publisher
    There is inconsistent evidence that increasing birth order may be associated with risk of non-Hodgkin lymphoma (NHL)...
  32. Swamy G, Edwards S, GELFAND A, James S, Miranda M. Maternal age, birth order, and race: differential effects on birthweight. J Epidemiol Community Health. 2012;66:136-42 pubmed publisher
    Studies examining the influence of maternal age and birth order on birthweight have not effectively disentangled the relative contributions of each factor to birthweight, especially as they may differ by race...
  33. Wells J, Hallal P, Reichert F, Dumith S, Menezes A, Victora C. Associations of birth order with early growth and adolescent height, body composition, and blood pressure: prospective birth cohort from Brazil. Am J Epidemiol. 2011;174:1028-35 pubmed publisher
    ..The magnitude of increased blood pressure is clinically significant; hence, birth order is an important developmental predictor of cardiovascular risk in this population...
  34. Haugaard L, Ajslev T, Zimmermann E, Angquist L, Sørensen T. Being an only or last-born child increases later risk of obesity. PLoS ONE. 2013;8:e56357 pubmed publisher
    Studies have suggested that number of siblings and birth order is associated with obesity. However, studies combining these exposures are needed...
  35. Berger I, Felsenthal Berger N. Attention-deficit hyperactivity disorder (ADHD) and birth order. J Child Neurol. 2009;24:692-6 pubmed publisher
    b>Birth order is considered one of the most influential environmental factors in child development, affecting cognitive abilities and behavioral traits...
  36. Sulloway F. Psychology. Birth order and intelligence. Science. 2007;316:1711-2 pubmed
  37. Wang H, Sekine M, Chen X, Kanayama H, Yamagami T, Kagamimori S. Sib-size, birth order and risk of overweight in junior high school students in Japan: results of the Toyama Birth Cohort Study. Prev Med. 2007;44:45-51 pubmed
    To investigate whether there is a relationship between sib-size, birth order and the risk of overweight in junior high school students...
  38. Savage T, Derraik J, Miles H, Mouat F, Cutfield W, Hofman P. Birth order progressively affects childhood height. Clin Endocrinol (Oxf). 2013;79:379-85 pubmed publisher
    ..Thus, we aimed to assess whether birth order was associated with changes in growth and metabolism in childhood...
  39. Rossi A, Mullin P, Chmait R. Neonatal outcomes of twins according to birth order, presentation and mode of delivery: a systematic review and meta-analysis. BJOG. 2011;118:523-32 pubmed publisher
    ..Studies selection criteria were: both twins alive at labour, outcomes stratified for birth order, presentation, planned and actual delivery mode...
  40. Zucker K, Blanchard R, Kim T, Pae C, Lee C. Birth order and sibling sex ratio in homosexual transsexual South Korean men: Effects of the male-preference stopping rule. Psychiatry Clin Neurosci. 2007;61:529-33 pubmed
    Two biodemographic variables - birth order and sibling sex ratio - have been examined in several Western samples of homosexual transsexual men...
  41. Gooren L. The biology of human psychosexual differentiation. Horm Behav. 2006;50:589-601 pubmed
    ..Genetic studies and the fraternal birth order hypothesis provide indications of familial clustering of homosexuality but in many homosexuals these genetic ..
  42. Dahly D, Adair L. Does lower birth order amplify the association between high socioeconomic status and central adiposity in young adult Filipino males?. Int J Obes (Lond). 2010;34:751-9 pubmed publisher
    To test the hypothesis that lower birth order amplifies the positive association between socioeconomic status and central adiposity in young adult males from a lower income, developing country context...
  43. El Gilany A, Hammad S. Epidemiology of diarrhoeal diseases among children under age 5 years in Dakahlia, Egypt. East Mediterr Health J. 2005;11:762-75 pubmed
    ..of diarrhoea was significantly higher among children in rural areas, those aged 6-24 months and of higher birth order, in the summer, when mothers were younger, had lower education or were not working, and when fathers had lower ..
  44. Ayyavoo A, Savage T, Derraik J, Hofman P, Cutfield W. First-born children have reduced insulin sensitivity and higher daytime blood pressure compared to later-born children. J Clin Endocrinol Metab. 2013;98:1248-53 pubmed publisher
    ..Therefore, we aimed to assess whether birth order would be associated with changes in metabolism in childhood...
  45. Carballo J, García Nieto R, Alvarez Garcia R, Caro Cañizares I, Lopez Castroman J, Muñoz Lorenzo L, et al. Sibship size, birth order, family structure and childhood mental disorders. Soc Psychiatry Psychiatr Epidemiol. 2013;48:1327-33 pubmed publisher
    The aim of this study was to determine the role that birth order, sibship size and family structure have as risk factors in the development of common childhood mental disorders. A case-control study design was conducted (N = 16,823)...
  46. Lawson D, Mace R. Sibling configuration and childhood growth in contemporary British families. Int J Epidemiol. 2008;37:1408-21 pubmed publisher
    ..Later-born children appear worst affected by within family resource division. ..
  47. Blanchard R, Lippa R. Birth order, sibling sex ratio, handedness, and sexual orientation of male and female participants in a BBC internet research project. Arch Sex Behav. 2007;36:163-76 pubmed
    This study investigated the relations among sexual orientation, fraternal birth order (number of older brothers), and hand-preference...
  48. Singh N, Pripp A, Brekke T, Stray Pedersen B. Different sex ratios of children born to Indian and Pakistani immigrants in Norway. BMC Pregnancy Childbirth. 2010;10:40 pubmed publisher
    ..Norway" and the female-to-male (F/M) sex ratio was evaluated among 21,325 children born, in increasing birth order, during three stratified periods (i.e., 1969-1986, 1987-1996, and 1997-2005)...
  49. Rahman Q, Symeonides D. Neurodevelopmental correlates of paraphilic sexual interests in men. Arch Sex Behav. 2008;37:166-72 pubmed
    ..It is suggested that processes such as developmental instability and maternal immunity may play a role in variant sexual preferences among otherwise healthy heterosexual men. ..
  50. Biswas S, Bose K. Sex differences in the effect of birth order and parents' educational status on stunting: a study on Bengalee preschool children from eastern India. Homo. 2010;61:271-6 pubmed publisher
    ..selected from 30 randomly selected ICDS centres to study the impact of parents' educational status and child birth order on stunting. The overall (age and sex combined) rate of stunting was 39.2%. Child birth order (BO) (chi(2)=14...
  51. Vivekananda U, Johnston C, McKenna Yasek D, Shaw C, Leigh P, Brown R, et al. Birth order and the genetics of amyotrophic lateral sclerosis. J Neurol. 2008;255:99-102 pubmed
    ..hypothesis that such a mechanism is responsible for sporadic ALS, we have performed a retrospective analysis of birth order position. We have analyzed sibships of size greater than four using a binomial test for birth position...
  52. Bernsen R, de Jongste J, van der Wouden J. Birth order and sibship size as independent risk factors for asthma, allergy, and eczema. Pediatr Allergy Immunol. 2003;14:464-9 pubmed
    This study was carried out to disentangle the independent relations of birth order and sibship size with the presence of asthma, allergy and eczema...
  53. MacCulloch S, Gray N, Phillips H, Taylor J, MacCulloch M. Birth order in sex-offending and aggressive-offending men. Arch Sex Behav. 2004;33:467-74 pubmed
    The relation between birth order and number of sexual and violent convictions was investigated retrospectively in a sample of 113 men, to determine whether the established fraternal birth order effect in male homosexual preference and ..