dysarthria

Summary

Summary: Disorders of speech articulation caused by imperfect coordination of pharynx, larynx, tongue, or face muscles. This may result from CRANIAL NERVE DISEASES; NEUROMUSCULAR DISEASES; CEREBELLAR DISEASES; BASAL GANGLIA DISEASES; BRAIN STEM diseases; or diseases of the corticobulbar tracts (see PYRAMIDAL TRACTS). The cortical language centers are intact in this condition. (From Adams et al., Principles of Neurology, 6th ed, p489)

Top Publications

  1. Gustaw K, Mirecka U. Dysarthria as the isolated clinical symptom of borreliosis--a case report. Ann Agric Environ Med. 2001;8:95-7 pubmed
    This report presents a case of dysarthria due to hypoglossal nerve mono-neuropathy as the only consequence of neuroborreliosis. The 65-year-old man with a seven-months history of articulation disturbances was examined...
  2. McAuliffe M, Carpenter S, Moran C. Speech intelligibility and perceptions of communication effectiveness by speakers with dysarthria following traumatic brain injury and their communication partners. Brain Inj. 2010;24:1408-15 pubmed publisher
    ..examined differences in perceived communicative effectiveness between a group of eight participants with chronic dysarthria following TBI and their nominated communication partners (TBIP)...
  3. Skodda S, Visser W, Schlegel U. Short- and long-term dopaminergic effects on dysarthria in early Parkinson's disease. J Neural Transm (Vienna). 2010;117:197-205 pubmed publisher
    ..As some improvement of vowel articulation was seen in individual patients, the pre-existing pattern of speech impairment might be responsible for the different response to pharmacological treatment...
  4. Marchant J, McAuliffe M, Huckabee M. Treatment of articulatory impairment in a child with spastic dysarthria associated with cerebral palsy. Dev Neurorehabil. 2008;11:81-90 pubmed
    A comparative study of treatment modalities for improving articulation in a 13-year-old child with severe spastic dysarthria associated with spastic cerebral palsy (SCP) was conducted.
  5. Hartelius L, Elmberg M, Holm R, Lovberg A, Nikolaidis S. Living with dysarthria: evaluation of a self-report questionnaire. Folia Phoniatr Logop. 2008;60:11-9 pubmed
    The study describes an effort to evaluate the speech difficulties as perceived by individuals with dysarthria. A self-report questionnaire, Living with Neurologically Based Speech Difficulties (Living with Dysarthria), was answered by 55 ..
  6. Walshe M, Peach R, Miller N. Dysarthria impact profile: development of a scale to measure psychosocial effects. Int J Lang Commun Disord. 2009;44:693-715 pubmed publisher
    The psychosocial impact of acquired dysarthria on the speaker is well recognized. To date, speech-and-language therapists have no instrument available to measure this construct...
  7. Bloch S, Beeke S. Co-constructed talk in the conversations of people with dysarthria and aphasia. Clin Linguist Phon. 2008;22:974-90 pubmed publisher
    ..By drawing attention to similarities in the consequences of dysarthria and aphasia in everyday interaction, it is suggested that researchers and clinicians might profitably look ..
  8. Wang Y, Kent R, Duffy J, Thomas J. Analysis of diadochokinesis in ataxic dysarthria using the motor speech profile program. Folia Phoniatr Logop. 2009;61:1-11 pubmed publisher
    ..study is to evaluate the suitability, reliability, and concurrent validity of the results from the DRA protocol and hand measurement for individuals with ataxic dysarthria, which is characteristically associated with dysdiadochokinesis.
  9. Van Nuffelen G, De Bodt M, Vanderwegen J, Van de Heyning P, Wuyts F. Effect of rate control on speech production and intelligibility in dysarthria. Folia Phoniatr Logop. 2010;62:110-9 pubmed publisher
    ..intelligibility, speaking rate (SR), articulation rate (AR) and pause characteristics in 27 individuals with dysarthria. The data reveal that with the exception of slower on demand, each RCM resulted in lower mean SRs and ARs (p <..

More Information

Publications62

  1. Ogawa K, Yoshihashi H, Suzuki Y, Kamei S, Mizutani T. Clinical study of the responsible lesion for dysarthria in the cerebellum. Intern Med. 2010;49:861-4 pubmed
    There have been few reports describing the lesion for cerebellar dysarthria. We compared MRI findings of 4 reported patients (including our previously reported patient) to that of our patient who showed ataxic speech and ataxic gait...
  2. Posada I, Gallardo M, Domínguez C, Rivera H, Cabello A, Arenas J, et al. [Mitochondrial DNA depletion and POLG mutations in a patient with sensory ataxia, dysarthria and ophthalmoplegia]. Med Clin (Barc). 2010;135:452-5 pubmed publisher
    ..We report on a patient having the clinical triad of sensory ataxic neuropathy, dysarthria and ophthalmoplegia (SANDO), POLG mutations and reduced muscle mtDNA content.
  3. Bowen A, Hesketh A, Patchick E, Young A, Davies L, Vail A, et al. Effectiveness of enhanced communication therapy in the first four months after stroke for aphasia and dysarthria: a randomised controlled trial. BMJ. 2012;345:e4407 pubmed publisher
    ..To assess the effectiveness of enhanced communication therapy in the first four months after stroke compared with an attention control (unstructured social contact)...
  4. Weiss M, Saneto R. Sensory ataxic neuropathy with dysarthria and ophthalmoparesis (SANDO) in late life due to compound heterozygous POLG mutations. Muscle Nerve. 2010;41:882-5 pubmed publisher
    ..The triad of sensory ataxic neuropathy, dysarthria, and ophthalmoparesis (SANDO) has been demonstrated in a small subset of patients with POLG1 mutations...
  5. Turner S, Hildebrand M, Block S, Damiano J, Fahey M, Reilly S, et al. Small intragenic deletion in FOXP2 associated with childhood apraxia of speech and dysarthria. Am J Med Genet A. 2013;161A:2321-6 pubmed publisher
    ..His phenotype included features of childhood apraxia of speech and dysarthria, oral motor dyspraxia, receptive and expressive language disorder, and literacy difficulties...
  6. Robbins M, Roth S, Swerdlow M, Bieri P, Herskovitz S. Optic neuritis and palatal dysarthria as presenting features of post-infectious GQ1b antibody syndrome. Clin Neurol Neurosurg. 2009;111:465-6 pubmed publisher
    ..man had optic neuritis 2 weeks after a diarrheal illness, followed by several deficits including palatal dysarthria, diplopia, ataxia, sensory dysfunction, and mild dysautonomia. Brain MRI and CSF were normal...
  7. Cohen S, Elackattu A, Noordzij J, Walsh M, Langmore S. Palliative treatment of dysphonia and dysarthria. Otolaryngol Clin North Am. 2009;42:107-21, x pubmed publisher
    ..For these patients there are a number of palliative interventions that can greatly improve their quality of life...
  8. Blanchet P, Snyder G. Speech rate treatments for individuals with dysarthria: a tutorial. Percept Mot Skills. 2010;110:965-82 pubmed
    Research confirms the long-standing clinical observation that patients with dysarthria exhibit variability in speech rate. Thus, modifying speech rate has been documented as one of the best treatment options for these patients...
  9. Bloch S, Wilkinson R. Acquired dysarthria in conversation: methods of resolving understandability problems. Int J Lang Commun Disord. 2011;46:510-23 pubmed publisher
    People with acquired progressive dysarthria typically experience increased problems with intelligibility in everyday conversation as their disease progresses...
  10. Rudzinski L, Fletcher R, Dickson D, Crook R, Hutton M, Adamson J, et al. Early onset familial Alzheimer Disease with spastic paraparesis, dysarthria, and seizures and N135S mutation in PSEN1. Alzheimer Dis Assoc Disord. 2008;22:299-307 pubmed publisher
  11. Dickson S, Barbour R, Brady M, Clark A, Paton G. Patients' experiences of disruptions associated with post-stroke dysarthria. Int J Lang Commun Disord. 2008;43:135-53 pubmed publisher
    Post-stroke dysarthria rehabilitation should consider social participation for people with dysarthria, but before this approach can be adopted, an understanding of the psychosocial impact of dysarthria is required...
  12. Liégeois F, Tournier J, Pigdon L, Connelly A, Morgan A. Corticobulbar tract changes as predictors of dysarthria in childhood brain injury. Neurology. 2013;80:926-32 pubmed publisher
    To identify corticobulbar tract changes that may predict chronic dysarthria in young people who have sustained a traumatic brain injury (TBI) in childhood using diffusion MRI tractography.
  13. Tripoliti E, Strong L, Hickey F, Foltynie T, Zrinzo L, Candelario J, et al. Treatment of dysarthria following subthalamic nucleus deep brain stimulation for Parkinson's disease. Mov Disord. 2011;26:2434-6 pubmed publisher
    ..Speech impairment is a frequent side effect of the surgery. This study examined the efficacy of an intensive speech treatment, the Lee Silverman Voice Treatment (LSVT) on dysarthria after STN-DBS.
  14. Long A, Hesketh A, Bowen A. Communication outcome after stroke: a new measure of the carer's perspective. Clin Rehabil. 2009;23:846-56 pubmed publisher
    ..To validate a measure of the carer's perspective of a stroke survivor's communication in everyday life...
  15. Brady M, Clark A, Dickson S, Paton G, Barbour R. Dysarthria following stroke: the patient's perspective on management and rehabilitation. Clin Rehabil. 2011;25:935-52 pubmed publisher
    To explore the perceptions of people with stroke-related dysarthria in relation to the management and rehabilitation of dysarthria.
  16. Hustad K. The relationship between listener comprehension and intelligibility scores for speakers with dysarthria. J Speech Lang Hear Res. 2008;51:562-73 pubmed publisher
    ..between listener comprehension and intelligibility scores for speakers with mild, moderate, severe, and profound dysarthria. Relationships were examined across all speakers and their listeners when severity effects were statistically ..
  17. Yunusova Y, Weismer G, Westbury J, Lindstrom M. Articulatory movements during vowels in speakers with dysarthria and healthy controls. J Speech Lang Hear Res. 2008;51:596-611 pubmed publisher
    ..lip, tongue blade, and dorsum during production of selected English vowels by normal speakers and speakers with dysarthria due to amyotrophic lateral sclerosis (ALS) or Parkinson disease (PD)...
  18. Tjaden K, Wilding G. The impact of rate reduction and increased loudness on fundamental frequency characteristics in dysarthria. Folia Phoniatr Logop. 2011;63:178-86 pubmed publisher
    ..with adjustments in utterance-level measures of fundamental frequency (F(0)) variability for speakers with dysarthria and healthy controls that have been shown to impact on intelligibility in previously published studies...
  19. Walshe M, Miller N. Living with acquired dysarthria: the speaker's perspective. Disabil Rehabil. 2011;33:195-203 pubmed publisher
    To explore the speaker's experience of living with acquired chronic dysarthria.
  20. Hill A, Theodoros D, Russell T, Ward E. The redesign and re-evaluation of an internet-based telerehabilitation system for the assessment of dysarthria in adults. Telemed J E Health. 2009;15:840-50 pubmed publisher
    A previous study revealed that reliable assessment of dysarthria was feasible...
  21. McHugh J, Lonergan R, Howley R, O Rourke K, Taylor R, Farrell M, et al. Sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO) in a sibling pair with a homozygous p.A467T POLG mutation. Muscle Nerve. 2010;41:265-9 pubmed publisher
    Two siblings who developed fifth-decade-onset, concurrent progressive sensory ataxia, dysarthria, and ophthalmoparesis were found to be homozygous for the p.A467T mutation of the polymerase gamma (POLG) gene...
  22. Sterling L, Jawaid A, Salamone A, Murthy S, Mosnik D, McDowell E, et al. Association between dysarthria and cognitive impairment in ALS: A prospective study. Amyotroph Lateral Scler. 2010;11:46-51 pubmed publisher
    ..An association between cognitive changes and bulbar site of onset or dysarthria has been suggested, but the findings are variable...
  23. Tomik B, Guiloff R. Dysarthria in amyotrophic lateral sclerosis: A review. Amyotroph Lateral Scler. 2010;11:4-15 pubmed publisher
    b>Dysarthria is a motor disorder of speech characterized by abnormalities of the articulation and intelligibility of speech. Phonation and the rate of facial movements may also be affected...
  24. Hiraga A, Tanaka S, Kamitsukasa I. Pure dysarthria due to an insular infarction. J Clin Neurosci. 2010;17:812-3 pubmed publisher
    Cortical infarction presenting with pure dysarthria is rarely reported. Previous studies have reported pure dysarthria due to cortical stroke at the precentral gyrus or middle frontal gyrus...
  25. Bloch S, Wilkinson R. Acquired dysarthria in conversation: identifying sources of understandability problems. Int J Lang Commun Disord. 2009;44:769-83 pubmed publisher
    Acquired progressive dysarthria is traditionally assessed, rated, and researched using measures of speech perception and intelligibility...
  26. Perez Lloret S, Negre Pages L, Ojero Senard A, Damier P, Destee A, Tison F, et al. Oro-buccal symptoms (dysphagia, dysarthria, and sialorrhea) in patients with Parkinson's disease: preliminary analysis from the French COPARK cohort. Eur J Neurol. 2012;19:28-37 pubmed publisher
    Abnormal oro-buccal functions including dysarthria, sialorrhea and dysphagia commonly affect patients with Parkinson's disease (PD).
  27. Smith M, Arnett P. Dysarthria predicts poorer performance on cognitive tasks requiring a speeded oral response in an MS population. J Clin Exp Neuropsychol. 2007;29:804-12 pubmed
    b>Dysarthria is a common symptom of multiple sclerosis (MS)...
  28. Morgan A, Masterton R, Pigdon L, Connelly A, Liégeois F. Functional magnetic resonance imaging of chronic dysarthric speech after childhood brain injury: reliance on a left-hemisphere compensatory network. Brain. 2013;136:646-57 pubmed publisher
    Severe and persistent speech disorder, dysarthria, may be present for life after brain injury in childhood, yet the neural correlates of this chronic disorder remain elusive...
  29. Uttner I, Kirchheiner J, Tumani H, Mottaghy F, Lebedeva E, Ozer E, et al. A novel presenilin1 mutation (Q223R) associated with early onset Alzheimer's disease, dysarthria and spastic paraparesis and decreased Abeta levels in CSF. Eur J Neurol. 2010;17:631-3 pubmed publisher
    ..The index patient was a 35-year-old man presenting with cognitive decline, behavioural symptoms, dysarthria, and gait disorder due to spasticity.
  30. Pennington L, Roelant E, Thompson V, Robson S, Steen N, Miller N. Intensive dysarthria therapy for younger children with cerebral palsy. Dev Med Child Neurol. 2013;55:464-71 pubmed publisher
    ..was to investigate if intervention targeting breath support, phonation, and speech rate increases speech intelligibility and participation in the conversational interactions of younger children with dysarthria and cerebral palsy (CP).
  31. McHenry M. The effect of pacing strategies on the variability of speech movement sequences in dysarthria. J Speech Lang Hear Res. 2003;46:702-10 pubmed
    There are many potential sources of variability in speech production, particularly in individuals with dysarthria. The degree and time course of stabilization of the speech production system during recovery from a neurological insult is ..
  32. Hawley M, Enderby P, Green P, Cunningham S, Brownsell S, Carmichael J, et al. A speech-controlled environmental control system for people with severe dysarthria. Med Eng Phys. 2007;29:586-93 pubmed
    ..Off-the-shelf ASR systems function poorly for users with severe dysarthria because of the increased variability of their articulations...
  33. Liss J, Spitzer S, Caviness J, Adler C, Edwards B. Lexical boundary error analysis in hypokinetic and ataxic dysarthria. J Acoust Soc Am. 2000;107:3415-24 pubmed
    ..error (LBE) analysis was conducted on listener transcripts from phrases produced by speakers with hypokinetic dysarthria, ataxic dysarthria, and normal controls...
  34. De Marco S, Squilloni E, Vigna L, Bertagnolio M, Sternberg C. Irinotecan chemotherapy associated with transient dysarthria and aphasia. Ann Oncol. 2004;15:1147-8 pubmed
  35. Jordan L, Hillis A. Disorders of speech and language: aphasia, apraxia and dysarthria. Curr Opin Neurol. 2006;19:580-5 pubmed
    We review recent important papers pertaining to acquired aphasia, apraxia of speech and dysarthria with special attention to clinically significant work published in the last 12 months.
  36. Polur P, Miller G. Investigation of an HMM/ANN hybrid structure in pattern recognition application using cepstral analysis of dysarthric (distorted) speech signals. Med Eng Phys. 2006;28:741-8 pubmed
    Computer speech recognition of individuals with dysarthria, such as cerebral palsy patients requires a robust technique that can handle conditions of very high variability and limited training data...
  37. Urban P, Rolke R, Wicht S, Keilmann A, Stoeter P, Hopf H, et al. Left-hemispheric dominance for articulation: a prospective study on acute ischaemic dysarthria at different localizations. Brain. 2006;129:767-77 pubmed
    b>Dysarthria is a frequent symptom in cerebral ischaemia. However, speech characteristics of these patients have not previously been investigated in relation to lesion site in a prospective study...
  38. Sidtis J, Gomez C, Groshong A, Strother S, Rottenberg D. Mapping cerebral blood flow during speech production in hereditary ataxia. Neuroimage. 2006;31:246-54 pubmed
    b>Dysarthria is a significant feature of the dominantly inherited spinocerebellar ataxias (SCA), but little is known about the patterns of brain activity associated with this disorder of motor speech control...
  39. Morgan J, Cavaliere R, Juel V. Reversible corpus callosum lesion in legionnaires' disease. J Neurol Neurosurg Psychiatry. 2004;75:651-4 pubmed
    ..Legionella pneumophila infection should be included in the differential diagnosis of conditions associated with reversible lesions of the corpus callosum...
  40. Rosen K, Kent R, Delaney A, Duffy J. Parametric quantitative acoustic analysis of conversation produced by speakers with dysarthria and healthy speakers. J Speech Lang Hear Res. 2006;49:395-411 pubmed
    This study's main purpose was to (a) identify acoustic signatures of hypokinetic dysarthria (HKD) that are robust to phonetic variation in conversational speech and (b) determine specific characteristics of the variability associated with ..
  41. Liss J, Spitzer S, Caviness J, Adler C. The effects of familiarization on intelligibility and lexical segmentation in hypokinetic and ataxic dysarthria. J Acoust Soc Am. 2002;112:3022-30 pubmed
    This study is the third in a series that has explored the source of intelligibility decrement in dysarthria by jointly considering signal characteristics and the cognitive-perceptual processes employed by listeners...
  42. Kyllerman M, Brandberg G, Wiklund L, Mansson J. Dysarthria, progressive parkinsonian features and symmetric necrosis of putamen in a family with painful lipomas (Dercum disease variant). Neuropediatrics. 2002;33:69-72 pubmed
    ..The disorder was associated with dysarthria, visual pursuit defect and progressive dystonia...
  43. Tjaden K, Wilding G. Rate and loudness manipulations in dysarthria: acoustic and perceptual findings. J Speech Lang Hear Res. 2004;47:766-83 pubmed
    ..in the size of the articulatory-acoustic working space and improved acoustic distinctiveness for speakers with dysarthria. Improved intelligibility also has been reported...
  44. Pinto S, Thobois S, Costes N, Le Bars D, Benabid A, Broussolle E, et al. Subthalamic nucleus stimulation and dysarthria in Parkinson's disease: a PET study. Brain. 2004;127:602-15 pubmed
    ..The effect of STN stimulation on parkinsonian dysarthria has not, however, been investigated using PET...
  45. Kent R, Kent J, Duffy J, Thomas J, Weismer G, Stuntebeck S. Ataxic dysarthria. J Speech Lang Hear Res. 2000;43:1275-89 pubmed
    Although ataxic dysarthria has been studied with various methods in several languages, questions remain concerning which features of the disorder are most consistent, which speaking tasks are most sensitive to the disorder, and whether ..
  46. Mackenzie C, Lowit A. Behavioural intervention effects in dysarthria following stroke: communication effectiveness, intelligibility and dysarthria impact. Int J Lang Commun Disord. 2007;42:131-53 pubmed
    b>Dysarthria is a common post-stroke presentation. Its management falls within the remit of the speech and language therapy profession. Little controlled evaluation of the effects of intervention for dysarthria in stroke has been reported.
  47. Tjaden K, Rivera D, Wilding G, Turner G. Characteristics of the lax vowel space in dysarthria. J Speech Lang Hear Res. 2005;48:554-66 pubmed
    It has been hypothesized that lax vowels may be relatively unaffected by dysarthria, owing to the reduced vocal tract shapes required for these phonetic events (G. S. Turner, K. Tjaden, & G. Weismer, 1995)...
  48. Doyle P, Leeper H, Kotler A, Thomas Stonell N, O NEILL C, Dylke M, et al. Dysarthric speech: a comparison of computerized speech recognition and listener intelligibility. J Rehabil Res Dev. 1997;34:309-16 pubmed
    ..Severity of dysarthria did appear to influence recognition of target stimuli...
  49. Hertrich I, Ackermann H. Temporal and spectral aspects of coarticulation in ataxic dysarthria: an acoustic analysis. J Speech Lang Hear Res. 1999;42:367-81 pubmed
  50. Ozawa Y, Shiromoto O, Ishizaki F, Watamori T. Symptomatic differences in decreased alternating motion rates between individuals with spastic and with ataxic dysarthria: an acoustic analysis. Folia Phoniatr Logop. 2001;53:67-72 pubmed
    ..differences in decreased oral alternating motion rates (AMRs) between individuals with spastic and with ataxic dysarthria. The subjects were 6 individuals with spastic dysarthria, 6 with ataxic dysarthria and 6 normal speakers...
  51. Sellars C, Hughes T, Langhorne P. Speech and language therapy for dysarthria due to non-progressive brain damage. Cochrane Database Syst Rev. 2005;:CD002088 pubmed
    b>Dysarthria is a common sequel of non-progressive brain damage (typically stroke and traumatic brain damage)...
  52. Kent R, Vorperian H, Kent J, Duffy J. Voice dysfunction in dysarthria: application of the Multi-Dimensional Voice Program. J Commun Disord. 2003;36:281-306 pubmed
    Phonatory dysfunction is a frequent component of dysarthria and often is a primary feature noted in clinical assessment. But the vocal impairment can be difficult to assess because (a)...
  53. Shelburne S, Kielhofner M, Tiwari P. Cerebellar involvement in legionellosis. South Med J. 2004;97:61-4 pubmed
    ..Finally, possible methods of pathogenicity are discussed including data regarding direct bacterial invasion, toxin production, and immune-mediated mechanisms...