laughter

Summary

Summary: An involuntary expression of merriment and pleasure; it includes the patterned motor responses as well as the inarticulate vocalization.

Top Publications

  1. Sarzi Braga S, Manni R, Pedretti R. Laughter-induced syncope. Lancet. 2005;366:426 pubmed
  2. Szameitat D, Alter K, Szameitat A, Darwin C, Wildgruber D, Dietrich S, et al. Differentiation of emotions in laughter at the behavioral level. Emotion. 2009;9:397-405 pubmed publisher
    Although laughter is important in human social interaction, its role as a communicative signal is poorly understood...
  3. Davila Ross M, Allcock B, Thomas C, Bard K. Aping expressions? Chimpanzees produce distinct laugh types when responding to laughter of others. Emotion. 2011;11:1013-20 pubmed publisher
    ..The present work examined laughter in chimpanzees to test whether nonhuman primates also use their expressions in such distinct ways...
  4. Krack P, Kumar R, Ardouin C, Dowsey P, McVicker J, Benabid A, et al. Mirthful laughter induced by subthalamic nucleus stimulation. Mov Disord. 2001;16:867-75 pubmed
    ..using high stimulation parameters (50% higher than therapeutic) induced funny associations, leading to infectious laughter and hilarity, whereas the therapeutic parameters induced a hypomanic behavior and marked improvement of akinesia...
  5. Overeem S, Reijntjes R, Huyser W, Lammers G, van Dijk J. Corticospinal excitability during laughter: implications for cataplexy and the comparison with REM sleep atonia. J Sleep Res. 2004;13:257-64 pubmed
    ..Although this may explain the suppression of H-reflexes during REM sleep, cataplexy and laughter, it is not the only explanation...
  6. Pearce J. Some neurological aspects of laughter. Eur Neurol. 2004;52:169-71 pubmed
    This brief survey of laughter attempts an analysis of its neurological mechanisms, evolution, role in social behaviour and its clinicopathological importance...
  7. Tateno A, Jorge R, Robinson R. Pathological laughing and crying following traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2004;16:426-34 pubmed
    ..examined the prevalence and clinical correlates of pathological laughing and crying (PLC) using the Pathological Laughter and Crying Scale (PLAC) in 92 consecutive patients with acute symptoms 3, 6, and 12 months after traumatic brain ..
  8. Gervais M, Wilson D. The evolution and functions of laughter and humor: a synthetic approach. Q Rev Biol. 2005;80:395-430 pubmed
    A number of recent hypotheses have attempted to explain the ultimate evolutionary origins of laughter and humor...
  9. Herring D, Burleson M, Roberts N, Devine M. Coherent with laughter: subjective experience, behavior, and physiological responses during amusement and joy. Int J Psychophysiol. 2011;79:211-8 pubmed publisher
    ..As predicted, participants reported more amusement, showed more positive facial expressions and laughter, and exhibited less heart rate deceleration and a larger increase in respiratory amplitude in response to the ..

More Information

Publications62

  1. Riem M, van IJzendoorn M, Tops M, Boksem M, Rombouts S, Bakermans Kranenburg M. No laughing matter: intranasal oxytocin administration changes functional brain connectivity during exposure to infant laughter. Neuropsychopharmacology. 2012;37:1257-66 pubmed publisher
    Infant laughter is a rewarding experience. It activates neural reward circuits and promotes parental proximity and care, thus facilitating parent-infant attachment...
  2. Takeda M, Hashimoto R, Kudo T, Okochi M, Tagami S, Morihara T, et al. Laughter and humor as complementary and alternative medicines for dementia patients. BMC Complement Altern Med. 2010;10:28 pubmed publisher
    ..Considering the individuality of dementia patients, applicability of laughter and humor therapy is discussed...
  3. Wortzel H, Oster T, Anderson C, Arciniegas D. Pathological laughing and crying : epidemiology, pathophysiology and treatment. CNS Drugs. 2008;22:531-45 pubmed
  4. Yun S, Jung W, Park S, Moon S, Park J, Ko C, et al. Hwangryunhaedogtang (huanglianjiedutang) treatment for pathological laughter after stroke and importance of patterns identification: a preliminary study. Am J Chin Med. 2007;35:725-33 pubmed
    ..of hwangryunhaedogtang (huanglianjiedutang) (HT) treatment for patients with post stroke pathological laughter (PL). Fourteen subjects were enrolled...
  5. Barbanti P, Fabbrini G, Berardelli A. Acute pathological laughter induced by sumatriptan. Cephalalgia. 2008;28:92-3 pubmed
  6. Panksepp J. Neuroevolutionary sources of laughter and social joy: modeling primal human laughter in laboratory rats. Behav Brain Res. 2007;182:231-44 pubmed
    ..positive, playful social situations, and may index willingness for social engagement, similar to human infantile laughter, which may mature into productive adult socio-sexual behaviors...
  7. Balick M, Lee R. The role of laughter in traditional medicine and its relevance to the clinical setting: healing with ha!. Altern Ther Health Med. 2003;9:88-91 pubmed
  8. Szameitat D, Darwin C, Wildgruber D, Alter K, Szameitat A. Acoustic correlates of emotional dimensions in laughter: arousal, dominance, and valence. Cogn Emot. 2011;25:599-611 pubmed publisher
    Although laughter plays an essential part in emotional vocal communication, little is known about the acoustical correlates that encode different emotional dimensions...
  9. Hayashi T, Murakami K. The effects of laughter on post-prandial glucose levels and gene expression in type 2 diabetic patients. Life Sci. 2009;85:185-7 pubmed publisher
    This report mainly summarizes the results of our study in which the physiological effects of laughter--as a positive emotional expression--were analyzed with respect to gene expression changes to demonstrate the hypothesis that the mind ..
  10. Mehu M, Dunbar R. Relationship between smiling and laughter in humans (Homo sapiens): testing the power asymmetry hypothesis. Folia Primatol (Basel). 2008;79:269-80 pubmed publisher
    ..Three affiliative behaviours were recorded by focal sampling: spontaneous smiles, deliberate smiles and laughter. Interestingly, young men showed significantly higher proportions of deliberate smiles in comparison to laughter ..
  11. Mendez M, Nakawatase T, Brown C. Involuntary laughter and inappropriate hilarity. J Neuropsychiatry Clin Neurosci. 1999;11:253-8 pubmed
    b>Laughter is a particularly human behavior. Neuropsychiatrists are faced with disorders of laughter, yet the nature of this behavior and its disturbances remains obscure...
  12. Amaki M, Kamide K, Takiuchi S, Niizuma S, Horio T, Kawano Y. A case of neurally mediated syncope induced by laughter successfully treated with combination of propranolol and midodrine. Int Heart J. 2007;48:123-7 pubmed
    A 69-year-old man had been suffering from recurrent syncope induced by laughter since the age of 58...
  13. Hayashi T, Urayama O, Kawai K, Hayashi K, Iwanaga S, Ohta M, et al. Laughter regulates gene expression in patients with type 2 diabetes. Psychother Psychosom. 2006;75:62-5 pubmed
    Positive emotions influence endocrinological and immunological response. This study examined the effect of laughter,as an expression of positive emotion, in terms of gene expression changes...
  14. Holmes C, Goldman M. Seizures presenting as incessant laughter: a case of gelastic epilepsy. J Emerg Med. 2012;43:e447-9 pubmed publisher
    Gelastic seizures are defined as seizure activity manifesting as laughter inappropriate to the situation, with supporting evidence on electroencephalogram or magnetic resonance imaging...
  15. Nwokah E, Hsu H, Davies P, Fogel A. The integration of laughter and speech in vocal communication: a dynamic systems perspective. J Speech Lang Hear Res. 1999;42:880-94 pubmed
    b>Laughter in infant-directed speech was examined in 13 mother-infant pairs to investigate the possible co-occurrence of speech and laughter...
  16. Liangas G, Morton J, Henry R. Mirth-triggered asthma: is laughter really the best medicine?. Pediatr Pulmonol. 2003;36:107-12 pubmed
    Mirthful emotions such as laughter and excitement are unrecognized but perhaps important triggers of asthma. Our study aimed to explore the prevalence, mechanisms, and associations of mirth-triggered asthma (MTA) in children...
  17. MacDonald C. A chuckle a day keeps the doctor away: therapeutic humor and laughter. J Psychosoc Nurs Ment Health Serv. 2004;42:18-25 pubmed
    There are several beneficial efforts attributed to humor and laughter, including improved immune function, increased pain tolerance, and decreased stress response...
  18. Keltner D, Bonanno G. A study of laughter and dissociation: distinct correlates of laughter and smiling during bereavement. J Pers Soc Psychol. 1997;73:687-702 pubmed
    b>Laughter facilitates the adaptive response to stress by increasing the psychological distance from distress and by enhancing social relations...
  19. Bhatjiwale M, Nadkarni T, Desai K, Goel A. Pathological laughter as a presenting symptom of massive trigeminal neuromas: report of four cases. Neurosurgery. 2000;47:469-71; discussion 471-2 pubmed
    ..is a report of four cases of huge trigeminal neuromas that presented with the principle symptom of pathological laughter (PL). All four patients were male and were in either the third or fourth decade of life...
  20. Siddiqui M, Fernandez H, Garvan C, Kirsch Darrow L, Bowers D, Rodriguez R, et al. Inappropriate crying and laughing in Parkinson disease and movement disorders. World J Biol Psychiatry. 2009;10:234-40 pubmed publisher
    ..PBA is characterized by uncontrollable laughter without mirth, or alternatively crying without the feeling of sadness...
  21. Bachorowski J, Smoski M, Owren M. The acoustic features of human laughter. J Acoust Soc Am. 2001;110:1581-97 pubmed
    Remarkably little is known about the acoustic features of laughter. Here, acoustic outcomes are reported for 1024 naturally produced laugh bouts recorded from 97 young adults as they watched funny video clips...
  22. Takahashi K, Iwase M, Yamashita K, Tatsumoto Y, Ue H, Kuratsune H, et al. The elevation of natural killer cell activity induced by laughter in a crossover designed study. Int J Mol Med. 2001;8:645-50 pubmed
    The elevation of natural killer cell activity (NKCA) by laughter was not confirmed due to incomplete methodology of previous studies although positive emotion is believed to be favorable for health...
  23. Toda M, Kusakabe S, Nagasawa S, Kitamura K, Morimoto K. Effect of laughter on salivary endocrinological stress marker chromogranin A. Biomed Res. 2007;28:115-8 pubmed
    We investigated the effect of laughter on salivary endocrinological stress marker chromogranin A (CgA)...
  24. Sander K, Brechmann A, Scheich H. Audition of laughing and crying leads to right amygdala activation in a low-noise fMRI setting. Brain Res Brain Res Protoc. 2003;11:81-91 pubmed
    ..This aspect was revealed by a low-noise fMRI protocol which presumably minimized confounding effects of stressful high-noise fMRI. ..
  25. Osaka N, Osaka M. Striatal reward areas activated by implicit laughter induced by mimic words in humans: a functional magnetic resonance imaging study. Neuroreport. 2005;16:1621-4 pubmed
    The neurobiological reward components of laughter induced by words were investigated...
  26. Overeem S, Taal W, Ocal Gezici E, Lammers G, van Dijk J. Is motor inhibition during laughter due to emotional or respiratory influences?. Psychophysiology. 2004;41:254-8 pubmed
    We compared the effects of laughter and several respiratory movements on spinal motor excitability to unravel their respective influences...
  27. Panksepp J, Burgdorf J. "Laughing" rats and the evolutionary antecedents of human joy?. Physiol Behav. 2003;79:533-47 pubmed
    ..patterns ( approximately 50-kHz chirps) in rats may have more than a passing resemblance to primitive human laughter. In this paper, we summarize a dozen reasons for the working hypothesis that such rat vocalizations reflect a ..
  28. Sander K, Scheich H. Left auditory cortex and amygdala, but right insula dominance for human laughing and crying. J Cogn Neurosci. 2005;17:1519-31 pubmed
    ..Both the original and time-reversed laughing and crying activated more strongly the right insula, which may be compatible with its assumed function in emotional self-awareness. ..
  29. Kimata H. Laughter counteracts enhancement of plasma neurotrophin levels and allergic skin wheal responses by mobile phone-mediated stress. Behav Med. 2004;29:149-52 pubmed
    b>Laughter caused by viewing a comic video (Rowan Atkinson's The Best Bits of Mr...
  30. Pioro E. Current concepts in the pharmacotherapy of pseudobulbar affect. Drugs. 2011;71:1193-207 pubmed publisher
    Arising in settings of CNS insult, pseudobulbar affect (PBA) consists of uncontrollable episodes of crying or laughter incongruent to the patient's mood...
  31. Hasan H, Hasan T. Laugh yourself into a healthier person: a cross cultural analysis of the effects of varying levels of laughter on health. Int J Med Sci. 2009;6:200-11 pubmed
    This cross-cultural study explored along with various personality factors the relationship between laughter and disease prevalence...
  32. Hudenko W, Stone W, Bachorowski J. Laughter differs in children with autism: an acoustic analysis of laughs produced by children with and without the disorder. J Autism Dev Disord. 2009;39:1392-400 pubmed publisher
    ..b>Laughter was recorded during a series of playful interactions with an examiner...
  33. Aguirregomozcorta M, Ramio Torrenta L, Gich J, Quiles A, Genis D. Paroxysmal dystonia and pathological laughter as a first manifestation of multiple sclerosis. Mult Scler. 2008;14:262-5 pubmed
    ..Pathological laughter is usually seen as a pseudobulbar palsy in some diffuse neurological diseases, but cases have been described, ..
  34. Hayashi K, Hayashi T, Iwanaga S, Kawai K, Ishii H, Shoji S, et al. Laughter lowered the increase in postprandial blood glucose. Diabetes Care. 2003;26:1651-2 pubmed
  35. Parvizi J, Joseph J, Press D, Schmahmann J. Pathological laughter and crying in patients with multiple system atrophy-cerebellar type. Mov Disord. 2007;22:798-803 pubmed
    ..We report our clinical and post mortem findings in a patient with MSA-C who exhibited pathological laughter in the absence of any congruent changes of mood...
  36. Bragg M. Fall about laughing: a case of laughter syncope. Emerg Med Australas. 2006;18:518-9 pubmed
    b>Laughter syncope is an unusual but recognized form of situational syncope likely to have a similar pathophysiological origin to tussive syncope. There are few case reports of this syndrome in the literature...
  37. Reddy V, Williams E, Vaughan A. Sharing humour and laughter in autism and Down's syndrome. Br J Psychol. 2002;93:219-42 pubmed
    Everyday humour and laughter can tell us about children's ability to engage with and understand others...
  38. Ishigami S, Nakajima A, Tanno M, Matsuzaki T, Suzuki H, Yoshino S. Effects of mirthful laughter on growth hormone, IGF-1 and substance P in patients with rheumatoid arthritis. Clin Exp Rheumatol. 2005;23:651-7 pubmed
    ..GH has been shown to be associated with joint symptoms such as pain and swelling. On the other hand, mirthful laughter has favorable effects on the neuroendocrine-immune system...
  39. Kimata H. Differential effects of laughter on allergen-specific immunoglobulin and neurotrophin levels in tears. Percept Mot Skills. 2004;98:901-8 pubmed
    b>Laughter after viewing a humorous video "Modern Times" decreased Japanese cedar pollen-specific immunoglobulin E (IgE) and IgG4 levels, while it enhanced Japanese cedar pollen-specific IgA levels in tears of patients with atopic ..
  40. Pettigrew J. Laughter abolishes binocular rivalry. Clin Exp Optom. 2005;88:39-45 pubmed
    ..The present study builds on an incidental observation that laughter stopped the rivalry alternations between horizontal and vertical and induced the mixed percept instead...
  41. Parvizi J, Anderson S, Martin C, Damasio H, Damasio A. Pathological laughter and crying: a link to the cerebellum. Brain. 2001;124:1708-19 pubmed
    Patients with pathological laughter and crying (PLC) are subject to relatively uncontrollable episodes of laughter, crying or both...
  42. Meyer M, Zysset S, von Cramon D, Alter K. Distinct fMRI responses to laughter, speech, and sounds along the human peri-sylvian cortex. Brain Res Cogn Brain Res. 2005;24:291-306 pubmed
    In this event-related fMRI study, 12 right-handed volunteers heard human laughter, sentential speech, and nonvocal sounds in which global temporal and harmonic information were varied whilst they were performing a simple auditory target ..
  43. Chow G, Desai D, Spragg D, Zakaria S. Laughter-induced left bundle branch block. J Cardiovasc Electrophysiol. 2012;23:1136-8 pubmed publisher
    ..case of a patient with ischemic heart disease and intermittent left bundle branch block, reproducibly induced by laughter. Following treatment of ischemia with successful deployment of a drug-eluting stent, no further episodes of ..
  44. Mahony D, Burroughs W, Hieatt A. The effects of laughter on discomfort thresholds: does expectation become reality?. J Gen Psychol. 2001;128:217-26 pubmed
    ..and relaxation have been controlled in previous studies as possible mechanisms for the effectiveness of mirthful laughter in coping with pain and discomfort. The purpose of this study is to control expectation of benefit from laughter...
  45. Sherman A, Sweeny T, Grabowecky M, Suzuki S. Laughter exaggerates happy and sad faces depending on visual context. Psychon Bull Rev. 2012;19:163-9 pubmed publisher
    b>Laughter is an auditory stimulus that powerfully conveys positive emotion. We investigated how laughter influenced the visual perception of facial expressions...
  46. Andreasen D, El Fassi D. [The Pilgaard-Dahl syndrome: laughter-induced pneumothorax]. Ugeskr Laeger. 2010;172:3496-8 pubmed
    ..The syndrome consists of laughter-induced pneumothorax in smoking middle-aged men when exposed to hearty humour...
  47. Marci C, Moran E, Orr S. Physiologic evidence for the interpersonal role of laughter during psychotherapy. J Nerv Ment Dis. 2004;192:689-95 pubmed
    The role of laughter during psychotherapy is poorly understood. This study examined 10 unique sessions of psychodynamic psychotherapy with digital videotape and simultaneous measures of skin conductivity (SC) from patients and therapists...
  48. Sperli F, Spinelli L, Pollo C, Seeck M. Contralateral smile and laughter, but no mirth, induced by electrical stimulation of the cingulate cortex. Epilepsia. 2006;47:440-3 pubmed
    The cerebral representation of laughter is dissociated. The emotional aspects seem to be processed in the temporal lobe; whereas the motor features apparently rely on the frontal cortex...
  49. Filippelli M, Pellegrino R, Iandelli I, Misuri G, Rodarte J, Duranti R, et al. Respiratory dynamics during laughter. J Appl Physiol (1985). 2001;90:1441-6 pubmed
    Lung and chest wall mechanics were studied during fits of laughter in 11 normal subjects. Laughing was naturally induced by showing clips of the funniest scenes from a movie by Roberto Benigni...
  50. Coelho M, Ferro J. Fou rire prodromique. Case report and systematic review of literature. Cerebrovasc Dis. 2003;16:101-4 pubmed
  51. Panksepp J, Burgdorf J. 50-kHz chirping (laughter?) in response to conditioned and unconditioned tickle-induced reward in rats: effects of social housing and genetic variables. Behav Brain Res. 2000;115:25-38 pubmed
    ..Overall, these results suggest that tickle evoked 50-kHz USVs may be a useful behavioral marker of positive social affect in rats. Difficulties with such concepts are also discussed. ..
  52. Vlachopoulos C, Xaplanteris P, Alexopoulos N, Aznaouridis K, Vasiliadou C, Baou K, et al. Divergent effects of laughter and mental stress on arterial stiffness and central hemodynamics. Psychosom Med. 2009;71:446-53 pubmed publisher
    To investigate the effect of laughter and mental stress on arterial stiffness and central hemodynamics. Arterial stiffness and wave reflections are independent predictors of cardiovascular risk...
  53. Hennenlotter A, Schroeder U, Erhard P, Castrop F, Haslinger B, Stoecker D, et al. A common neural basis for receptive and expressive communication of pleasant facial affect. Neuroimage. 2005;26:581-91 pubmed
    ..Such a mechanism is suggested to be important for empathic understanding of others' feelings. ..