technology transfer


Summary: Spread and adoption of inventions and techniques from one geographic area to another, from one discipline to another, or from one sector of the economy to another. For example, improvements in medical equipment may be transferred from industrial countries to developing countries, advances arising from aerospace engineering may be applied to equipment for persons with disabilities, and innovations in science arising from government research are made available to private enterprise.

Top Publications

  1. Campbell E, Bendavid E. Data-sharing and data-withholding in genetics and the life sciences: results of a national survey of technology transfer officers. J Health Care Law Policy. 2003;6:241-55 pubmed
  2. Ventura R, Brunner L, Heriyanto B, de Boer O, O HARA M, Huynh C, et al. Technology transfer of an oil-in-water vaccine-adjuvant for strengthening pandemic influenza preparedness in Indonesia. Vaccine. 2013;31:1641-5 pubmed publisher
    ..The Vaccine Formulation Laboratory at University of Lausanne is engaged in the technology transfer of an antigen-sparing oil-in-water adjuvant in order to empower developing countries vaccine manufacturers ..
  3. Mátés L, Izsvák Z, Ivics Z. Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives. Genome Biol. 2007;8 Suppl 1:S1 pubmed
  4. Looby M, Ibarra N, Pierce J, Buckley K, O Donovan E, Heenan M, et al. Application of quality by design principles to the development and technology transfer of a major process improvement for the manufacture of a recombinant protein. Biotechnol Prog. 2011;27:1718-29 pubmed publisher
  5. Ozaki D, Gao H, Todd C, Greene K, Montefiori D, Sarzotti Kelsoe M. International technology transfer of a GCLP-compliant HIV-1 neutralizing antibody assay for human clinical trials. PLoS ONE. 2012;7:e30963 pubmed publisher
    ..As a result, several of the CAVD/CA-VIMC Regional Laboratories are now in the process of conducting or planning to conduct the GCLP-compliant TZM-bl NAb Assay as an indicator of vaccine immunogenicity for ongoing human clinical trials. ..
  6. Bakker W, Thomassen Y, van t Oever A, Westdijk J, van Oijen M, Sundermann L, et al. Inactivated polio vaccine development for technology transfer using attenuated Sabin poliovirus strains to shift from Salk-IPV to Sabin-IPV. Vaccine. 2011;29:7188-96 pubmed publisher
    ..Also, results will be shown from large-scale (to prepare for future technology transfer) generation of Master- and Working virus seedlots, and clinical trial material (for phase I studies) ..
  7. Grossi E. Technology transfer from the science of medicine to the real world: the potential role played by artificial adaptive systems. Subst Use Misuse. 2007;42:267-304 pubmed
    ..These tools can allow a more efficient technology transfer from the science of medicine to the real world, overcoming many obstacles responsible for the present ..
  8. Dyrskjøt L, Reinert T, Novoradovsky A, Zuiverloon T, Beukers W, Zwarthoff E, et al. Analysis of molecular intra-patient variation and delineation of a prognostic 12-gene signature in non-muscle invasive bladder cancer; technology transfer from microarrays to PCR. Br J Cancer. 2012;107:1392-8 pubmed publisher
    ..A PCR-based 12-gene signature significantly predicts disease progression in patients with non-muscle invasive bladder cancer. ..
  9. Squires D, Gumbley S, Storti S. Training substance abuse treatment organizations to adopt evidence-based practices: the Addiction Technology Transfer Center of New England Science to Service Laboratory. J Subst Abuse Treat. 2008;34:293-301 pubmed
    ..To help address this gap, the Addiction Technology Transfer Center of New England (ATTC-NE), located at Brown University, has adapted and implemented an organizational ..

More Information


  1. Plebani M, Marincola F. Research translation: a new frontier for clinical laboratories. Clin Chem Lab Med. 2006;44:1303-12 pubmed
  2. Kreeftenberg H, van der Velden T, Kersten G, van der Heuvel N, de Bruijn M. Technology transfer of Sabin-IPV to new developing country markets. Biologicals. 2006;34:155-8 pubmed
    ..This paper discusses the approach followed and the experience already gained in the project, as well as factors critical to its success. ..
  3. Pearson H. Translational research: a case history. Nature. 2008;453:846-9 pubmed publisher
  4. Wasan K, Thornton S, Bell I, Goulding R, Gretes M, Gray A, et al. The global access initiative at the University of British Columbia (UBC): Availability of UBC discoveries and technologies to the developing world. J Pharm Sci. 2009;98:791-4 pubmed publisher
    ..This commentary will discuss these principles and provide examples of where they have been applied to several UBC technologies. ..
  5. Veniegas R, Kao U, Rosales R, Arellanes M. HIV prevention technology transfer: challenges and strategies in the real world. Am J Public Health. 2009;99 Suppl 1:S124-30 pubmed publisher
    ..the phases (preimplementation, implementation, and maintenance and evolution) and activities defined by the technology transfer model for evidence-based HIV prevention interventions...
  6. Baer J, Wells E, Rosengren D, Hartzler B, Beadnell B, Dunn C. Agency context and tailored training in technology transfer: a pilot evaluation of motivational interviewing training for community counselors. J Subst Abuse Treat. 2009;37:191-202 pubmed publisher
  7. Bubela T, Caulfield T. Role and reality: technology transfer at Canadian universities. Trends Biotechnol. 2010;28:447-51 pubmed publisher
    b>Technology transfer offices (TTOs) play a central role in the knowledge translation and commercialization agenda of Canadian universities...
  8. Friede M, Palkonyay L, Alfonso C, Pervikov Y, Torelli G, Wood D, et al. WHO initiative to increase global and equitable access to influenza vaccine in the event of a pandemic: supporting developing country production capacity through technology transfer. Vaccine. 2011;29 Suppl 1:A2-7 pubmed publisher
    ..g. those that allow significant dose-sparing. To this end, the influenza vaccine technology transfer initiative was launched in 2007 and, to date, vaccine manufacturers in 11 developing countries have ..
  9. Miyaki C, Meros M, Precioso A, Raw I. Influenza vaccine production for Brazil: a classic example of successful North-South bilateral technology transfer. Vaccine. 2011;29 Suppl 1:A12-5 pubmed publisher
    b>Technology transfer is a promising approach to increase vaccine production at an affordable price in developing countries...
  10. Kesselheim A, Avorn J. University-based science and biotechnology products: defining the boundaries of intellectual property. JAMA. 2005;293:850-4 pubmed
  11. Morel C, Acharya T, Broun D, Dangi A, Elias C, Ganguly N, et al. Health innovation networks to help developing countries address neglected diseases. Science. 2005;309:401-4 pubmed
    ..Here we highlight a complementary and increasingly important means to improve health equity: the growing ability of some developing countries to undertake health innovation. ..
  12. Tesfaye A, Jemal I, Ferede S, Martin Curran M. Technology transfer pathways and livelihood impact indicators in central Ethiopia. Trop Anim Health Prod. 2005;37 Suppl 1:101-22 pubmed
    ..The results showed that there are many opportunities for group dissemination by making use of existing social networks. There are also opportunities for dissemination through extension agents, farmer groups and radio broadcasting...
  13. Sloboda Z, Schildhaus S. A discussion of the concept of technology transfer of research-based drug "abuse" prevention and treatment interventions. Subst Use Misuse. 2002;37:1079-87 pubmed
    ..Several theoretical perspectives that have not been brought into the technology transfer discussion are mentioned, others need to be reviewed for their potential to guide further research in this ..
  14. Southon F, Sauer C, Grant C. Information technology in complex health services: organizational impediments to successful technology transfer and diffusion. J Am Med Inform Assoc. 1997;4:112-24 pubmed
    ..There is a need to take a more sophisticated approach to understanding the complexities of organizational factors than has traditionally been the case. ..
  15. Brown B, Flynn P. The federal role in drug abuse technology transfer: a history and perspective. J Subst Abuse Treat. 2002;22:245-57 pubmed
    ..more effective in achieving the individual and organizational behavior change needed to achieve technology transfer. Argument is made that the federal government remains the best, if not the only resource for promoting ..
  16. Neumann M, Sogolow E. Replicating effective programs: HIV/AIDS prevention technology transfer. AIDS Educ Prev. 2000;12:35-48 pubmed
    ..The experience of the REP project indicates that technology transfer is complex. Interventions need to be adapted to local circumstances...
  17. Kraft J, Mezoff J, Sogolow E, Neumann M, Thomas P. A technology transfer model for effective HIV/AIDS interventions: science and practice. AIDS Educ Prev. 2000;12:7-20 pubmed
    ..Starting with a review of diffusion of innovations and technology transfer literature, we offer a technology transfer model for HIV interventions...
  18. Heller M, Eisenberg R. Can patents deter innovation? The anticommons in biomedical research. Science. 1998;280:698-701 pubmed
    ..Otherwise, more intellectual property rights may lead paradoxically to fewer useful products for improving human health. ..
  19. Lloyd J, Milstien J. Auto-disable syringes for immunization: issues in technology transfer. Bull World Health Organ. 1999;77:1001-7 pubmed
    ..The present article examines factors influencing technology transfer, including feasibility, corporate interest, cost, quality assurance, intellectual property considerations, ..
  20. Andrzejewski M, Kirby K, Morral A, Iguchi M. Technology transfer through performance management: the effects of graphical feedback and positive reinforcement on drug treatment counselors' behavior. Drug Alcohol Depend. 2001;63:179-86 pubmed
    ..Nonetheless, present results show promise that feedback and positive reinforcement could be used to improve technology transfer of behavioral interventions into community clinic settings.
  21. Lane J, Leahy J, Bauer S. Accomplishing technology transfer: case-based lessons of what works and what does not. Assist Technol. 2003;15:69-88 pubmed
    This paper presents lessons drawn from technology transfer case studies that address the persistent question: "What works, what does not, and why?" Each lesson highlights critical factors determining success or failure and is ..
  22. Campbell E, Powers J, Blumenthal D, Biles B. Inside the triple helix: technology transfer and commercialization in the life sciences. Health Aff (Millwood). 2004;23:64-76 pubmed
    ..bias in the reporting of results, limited revenues from these activities, and the lack of data to evaluate technology transfer activities...
  23. Zerhouni E. Translational and clinical science--time for a new vision. N Engl J Med. 2005;353:1621-3 pubmed
  24. Salicrup L, Fedorkova L. Challenges and opportunities for enhancing biotechnology and technology transfer in developing countries. Biotechnol Adv. 2006;24:69-79 pubmed
    ..The challenge, however, lies in defining the role of technology transfer to develop therapies for diseases prevalent in developing countries...
  25. Johnston K, Kennedy C, Murdoch I, Taylor P, Cook C. The cost-effectiveness of technology transfer using telemedicine. Health Policy Plan. 2004;19:302-9 pubmed
    ..b>Technology transfer is one way to improve specialist skills whilst at the same time reducing the burden of disease...
  26. Kaiser J. Technology transfer: U.S. scientists faulted on biotech consulting. Science. 2004;304:1222 pubmed
  27. Zhang Q, Zhang R, Qiu J, Zhang J, Wang X, Jiang L, et al. One-year clinical outcome of interventionalist- versus patient-transfer strategies for primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction: results from the REVERSE-STEMI study. Circ Cardiovasc Qual Outcomes. 2011;4:355-62 pubmed publisher
  28. Reisinger K, Casanova H, Wu Y, Moorer C. Comparison of á priori alignment techniques for transtibial prostheses in the developing world - pilot study. Disabil Rehabil. 2007;29:863-72 pubmed
    ..A second goal was to assess the feasibility of technology transfer for providing prosthetic services to remote areas of landmine-affected countries...
  29. Ng S, Kessler L, Srivastava R, Dusek J, Duncan D, Tansey M, et al. Growing practice specialists in mental health: addressing stigma and recruitment with a nursing residency program. Nurs Leadersh (Tor Ont). 2010;23 Spec No 2010:101-12 pubmed
    ..In this paper, we describe our journey in designing and implementing a nursing residency program for other nurse leaders interested in providing a similar program to build on our experience. ..
  30. Rees B, Spiekstra S, Carfi M, Ouwehand K, Williams C, Corsini E, et al. Inter-laboratory study of the in vitro dendritic cell migration assay for identification of contact allergens. Toxicol In Vitro. 2011;25:2124-34 pubmed publisher
    ..The results were consistent between the laboratories, and the dose response data were reproduced in the three laboratories. ..
  31. Zmorzynska A, Suk J, Biederbick W, Maidhof H, Sasse J, Semenza J, et al. Unfinished business: efforts to define dual-use research of bioterrorism concern. Biosecur Bioterror. 2011;9:372-8 pubmed publisher
    ..Additionally, we note that the 11 activities identified are not easily conducted or replicated, and therefore the likelihood of their being used in a high-tech mass casualty bioterrorism event should be reevaluated. ..
  32. Aguilar A, Bochereau L, Matthiessen Guyader L. Biotechnology and sustainability: the role of transatlantic cooperation in research and innovation. Trends Biotechnol. 2008;26:163-5 pubmed publisher
  33. Kayyal M, Gibbs T. Applying a quality assurance system model to curriculum transformation: transferable lessons learned. Med Teach. 2012;34:e690-7 pubmed publisher
    ..We perceive that the lessons learned from this activity are capable of being translated to other Universities, in other similar developing countries; our hope is that others can learn from our experiences. ..
  34. Fernández J, Stein R, Lo A. Commercializing biomedical research through securitization techniques. Nat Biotechnol. 2012;30:964-75 pubmed
    ..9–11.4% for equity holders and 5–8% for 'research-backed obligation' holders, which are lower than typical venture-capital hurdle rates but attractive to pension funds, insurance companies and other large institutional investors. ..
  35. Smaglik P. Northern exposure. Nature. 2006;443:1026-27 pubmed
  36. Moore D, Bayne K, Barnard T. Science as a service: understanding successful knowledge transfer in a New Zealand research institute. Work. 2012;41 Suppl 1:642-7 pubmed publisher
    ..The methodology had three parts. A review of the knowledge and technology transfer literature; a series of 15 semi-structured interviews with science leaders; and a facilitated workshop...
  37. Salinas Miranda A, Nash M, Salemi J, Mbah A, Salihu H. Cutting-edge technology for public health workforce training in comparative effectiveness research. Health Informatics J. 2013;19:101-15 pubmed publisher
  38. Levinson D. Genetics and suicidal ideation during antidepressant treatment. Am J Psychiatry. 2008;165:395; author reply 395-6 pubmed publisher
  39. Navarro M, Modena K, Freitas M, Fagundes T. Transferring ART research into education in Brazil. J Appl Oral Sci. 2009;17 Suppl:99-105 pubmed
    ..This will facilitate and standardize the introduction and adoption of the ART approach in undergraduate education in Brazil. ..
  40. Matsuo K, Runge H, Miller D, Barak Bernhagen M, Boedeker B. Technology transfer at the University of Nebraska Medical Center. Stud Health Technol Inform. 2011;163:351-3 pubmed begin the process of developing his or her idea, and then two pathways that occur simultaneously: the Technology Transfer process of patenting, marketing, and licensing the invention; and the engineering process of developing, ..
  41. Anfossi L, D Arco G, Calderara M, Baggiani C, Giovannoli C, Giraudi G. Development of a quantitative lateral flow immunoassay for the detection of aflatoxins in maize. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011;28:226-34 pubmed publisher
    ..97x + 0.07, r²= 0.980) when data was compared with that obtained through an official method. The developed method is reliable, rapid and allows for application outside the laboratory as a point-of-use test for screening purposes. ..
  42. Higginbotham D, Beukelman D, Blackstone S, Bryen D, Caves K, DeRuyter F, et al. AAC technology transfer: an AAC-RERC report. Augment Altern Commun. 2009;25:68-76 pubmed publisher
    ..The purpose of this article is to discuss barriers to technology transfer, to outline some technology transfer strategies, and to illustrate these strategies with AAC-RERC related ..
  43. Balser J, Baruchin A. Science at the interstices: an evolution in the academy. Acad Med. 2008;83:827-31 pubmed publisher
    ..The authors discuss potential models that could serve to lower barriers to interdisciplinary science, promoting a new synergy between AMCs and their parent universities. ..
  44. MCBRIDE D. Giant database allows scientists to share information. ONS Connect. 2008;23:22 pubmed
  45. Gerhardt R, Adams B, De Lorenzo R, Godinez F, Crawford D, Gruppo L, et al. Panel synopsis: pre-hospital combat health support 2010: what should our azimuth be?. J Trauma. 2007;62:S15-6 pubmed
  46. Bergman K, Graff G. The global stem cell patent landscape: implications for efficient technology transfer and commercial development. Nat Biotechnol. 2007;25:419-24 pubmed
  47. Fernandes M, Miska D. Beyond Bayh-Dole and the Lambert Review: an initial product development and transaction model for the interface between universities and business. Biotechnol Genet Eng Rev. 2004;21:249-76 pubmed
  48. Stanbrook M, Austin P, Redelmeier D. Acronym-named randomized trials in medicine--the ART in medicine study. N Engl J Med. 2006;355:101-2 pubmed
  49. Noblin A, Cortelyou Ward K, Liu D. The use of governance tools in promotion of health care information technology adoption by physicians. Health Care Manag (Frederick). 2011;30:250-60 pubmed publisher
    ..Grants, loans, and tax expenditures are some of the options available to physicians to purchase electronic health records and other types of health care information technology. ..
  50. Househ M, Kushniruk A, Carleton B, Cloutier Fisher D. A literature review on distance knowledge exchange in healthcare groups: what can we learn from the ICT literature?. J Med Syst. 2011;35:639-46 pubmed publisher
    ..A discussion of how ICTs could impact the social interaction process of knowledge exchange activities is made. ..
  51. Mazur L, Chen S. An empirical study for medication delivery improvement based on healthcare professionals' perceptions of medication delivery system. Health Care Manag Sci. 2009;12:56-66 pubmed
    ..The outcomes of this research are a theoretical model for reducing medication delivery errors and a set ofworkflow design rules for healthcare professionals to continuously reduce medication delivery errors. ..
  52. Padhy A, Dondi M. Thematic planning: the role of the International Atomic Energy Agency in promoting education, medical research, and technology transfer among nuclear medicine communities of developing countries. Semin Nucl Med. 2008;38:S2-4 pubmed publisher
  53. Piette J, List J, Rana G, Townsend W, Striplin D, Heisler M. Mobile Health Devices as Tools for Worldwide Cardiovascular Risk Reduction and Disease Management. Circulation. 2015;132:2012-27 pubmed publisher
    ..Next-generation mHealth programs developed worldwide should be based on evidence-based behavioral theories and incorporate advances in artificial intelligence for adapting systems automatically to patients' unique and changing needs. ..