allergic bronchopulmonary aspergillosis

Summary

Summary: Hypersensitivity reaction (ALLERGIC REACTION) to fungus ASPERGILLUS in an individual with long-standing BRONCHIAL ASTHMA. It is characterized by pulmonary infiltrates, EOSINOPHILIA, elevated serum IMMUNOGLOBULIN E, and skin reactivity to Aspergillus antigen.

Top Publications

  1. O Connor T, O DONNELL A, Hurley M, Bredin C. Allergic bronchopulmonary aspergillosis: a rare cause of pleural effusion. Respirology. 2001;6:361-3 pubmed
    Aspergillus fumigatus is one of the most ubiquitous of the airborne saprophytic fungi. Allergic bronchopulmonary aspergillosis (ABPA) is a syndrome seen in patients with asthma and cystic fibrosis, and is characterized by ..
  2. Vaid M, Kaur S, Sambatakou H, Madan T, Denning D, Sarma P. Distinct alleles of mannose-binding lectin (MBL) and surfactant proteins A (SP-A) in patients with chronic cavitary pulmonary aspergillosis and allergic bronchopulmonary aspergillosis. Clin Chem Lab Med. 2007;45:183-6 pubmed
    ..Patients with chronic cavitary pulmonary aspergillosis (CCPA; n=15) or allergic bronchopulmonary aspergillosis (ABPA; n=7) of Caucasian origin were screened for single nucleotide polymorphisms (SNPs) in the ..
  3. Garcia G, Humbert M, Capel F, Rimaniol A, Escourrou P, Emilie D, et al. Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis. Allergy. 2007;62:170-7 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a rare variant of severe asthma resulting from hypersensitivity to Aspergillus fumigatus (Asp f) present in the airways...
  4. Kreindler J, Steele C, Nguyen N, Chan Y, Pilewski J, Alcorn J, et al. Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis. J Clin Invest. 2010;120:3242-54 pubmed publisher
    b>Allergic bronchopulmonary aspergillosis (ABPA) is caused by a dominant Th2 immune response to antigens derived from the opportunistic mold Aspergillus, most commonly Aspergillus fumigatus...
  5. Saxena S, Madan T, Shah A, Muralidhar K, Sarma P. Association of polymorphisms in the collagen region of SP-A2 with increased levels of total IgE antibodies and eosinophilia in patients with allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol. 2003;111:1001-7 pubmed
    ..association of polymorphisms in the collagen region of SP-A1 and SP-A2 (genes encoding SP-A) with allergic bronchopulmonary aspergillosis (ABPA) and its clinical markers...
  6. Blease K, Mehrad B, Standiford T, Lukacs N, Gosling J, Boring L, et al. Enhanced pulmonary allergic responses to Aspergillus in CCR2-/- mice. J Immunol. 2000;165:2603-11 pubmed
    ..Thus, these findings demonstrate that CCR2 plays an important role in the immune response against A. fumigatus, thereby limiting the allergic airway inflammatory and remodeling responses to this fungus. ..
  7. Moss R. Pathophysiology and immunology of allergic bronchopulmonary aspergillosis. Med Mycol. 2005;43 Suppl 1:S203-6 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a complication of persistent asthma and cystic fibrosis (CF), diseases in part characterized by excessive viscous mucus and compromised mucociliary clearance...
  8. Chakrabarti A, Sethi S, Raman D, Behera D. Eight-year study of allergic bronchopulmonary aspergillosis in an Indian teaching hospital. Mycoses. 2002;45:295-9 pubmed
    A total of 651 patients with clinically suspected allergic bronchopulmonary aspergillosis (ABPA) were evaluated during the 8-year period from January 1991 to December 1998. Overall, 338 cases (51...
  9. Lin R, Sethi S, Bhargave G. Measured immunoglobulin E in allergic bronchopulmonary aspergillosis treated with omalizumab. J Asthma. 2010;47:942-5 pubmed publisher
    The ability to assess adequate reductions in immunoglobulin E (IgE) in allergic bronchopulmonary aspergillosis (ABPA) has been a concern with regards to omalizumab treatment...

More Information

Publications72

  1. Scheer B, Hutcheson P, Lagos J, Wood J, Slavin R. Mucoid impaction: a localized form of allergic bronchopulmonary aspergillosis. Allergy Asthma Proc. 2004;25:229-32 pubmed
    ..There are striking similarities between patients with mucoid impaction and those with allergic bronchopulmonary aspergillosis (ABPA), often referred to as "mucoid microimpaction...
  2. Agarwal R, Gupta D, Aggarwal A, Saxena A, Chakrabarti A, Jindal S. Clinical significance of hyperattenuating mucoid impaction in allergic bronchopulmonary aspergillosis: an analysis of 155 patients. Chest. 2007;132:1183-90 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a disease that presents with diverse clinicoradiologic manifestations...
  3. Krasnick J, Greenberger P, Roberts M, Patterson R. Allergic bronchopulmonary aspergillosis: serologic update for 1995. J Clin Lab Immunol. 1995;46:137-42 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a complex disease occurring in 1-2% of patients with asthma involving hypersensitivity to Aspergillus species...
  4. Zirbes J, Milla C. Steroid-sparing effect of omalizumab for allergic bronchopulmonary aspergillosis and cystic fibrosis. Pediatr Pulmonol. 2008;43:607-10 pubmed publisher
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a complication commonly encountered in patients with CF that produces significant respiratory morbidity...
  5. Kraemer R, Deloséa N, Ballinari P, Gallati S, Crameri R. Effect of allergic bronchopulmonary aspergillosis on lung function in children with cystic fibrosis. Am J Respir Crit Care Med. 2006;174:1211-20 pubmed
    ..The relationship between sensitization to Aspergillus fumigatus and progression of pulmonary function is not yet established in cystic fibrosis (CF)...
  6. Knutsen A, Hutcheson P, Slavin R, Kurup V. IgE antibody to Aspergillus fumigatus recombinant allergens in cystic fibrosis patients with allergic bronchopulmonary aspergillosis. Allergy. 2004;59:198-203 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) in cystic fibrosis (CF) is characterized by a heightened Th2 CD4+ T-cell response to Aspergillus fumigatus (Af) allergens and a hyper-immunoglobulin E (IgE) state compared with cystic ..
  7. Kurup V, Grunig G. Animal models of allergic bronchopulmonary aspergillosis. Mycopathologia. 2002;153:165-77 pubmed
    ..Among the different allergic diseases caused by this fungus, allergic bronchopulmonary aspergillosis (ABPA) is by far the most significant one...
  8. Hemmann S, Menz G, Ismail C, Blaser K, Crameri R. Skin test reactivity to 2 recombinant Aspergillus fumigatus allergens in A fumigatus-sensitized asthmatic subjects allows diagnostic separation of allergic bronchopulmonary aspergillosis from fungal sensitization. J Allergy Clin Immunol. 1999;104:601-7 pubmed
    ..Among these, allergic bronchopulmonary aspergillosis (ABPA) represents a complex clinical syndrome that is difficult to diagnose...
  9. Tillie Leblond I, Tonnel A. Allergic bronchopulmonary aspergillosis. Allergy. 2005;60:1004-13 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) occurs in nonimmunocompromised patients and belongs to the hypersensitivity disorders induced by Aspergillus...
  10. Agarwal R, Aggarwal A, Gupta D. High-attenuation mucus in allergic bronchopulmonary aspergillosis: another cause of diffuse high-attenuation pulmonary abnormality. AJR Am J Roentgenol. 2006;186:904 pubmed
  11. Wark P, Gibson P. Allergic bronchopulmonary aspergillosis: new concepts of pathogenesis and treatment. Respirology. 2001;6:1-7 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a condition that results from a hypersensitivity reaction to the fungus Aspergillus fumigatus...
  12. Vlahakis N, Aksamit T. Diagnosis and treatment of allergic bronchopulmonary aspergillosis. Mayo Clin Proc. 2001;76:930-8 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed pulmonary disorder in asthmatic patients and patients with cystic fibrosis...
  13. Hogaboam C, Gallinat C, Taub D, Strieter R, Kunkel S, Lukacs N. Immunomodulatory role of C10 chemokine in a murine model of allergic bronchopulmonary aspergillosis. J Immunol. 1999;162:6071-9 pubmed
    ..role of the chemokine C10 was explored in allergic airway responses during experimental allergic bronchopulmonary aspergillosis (ABPA). The intratracheal delivery of Asperigillus fumigatus Ag into A...
  14. Kumar R, Chopra D, Chopra R. Evaluation of allergic bronchopulmonary aspergillosis in patients with and without central bronchiectasis. J Asthma. 2002;39:473-7 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity disorder induced by Aspergillus species colonizing the bronchial tree. Thirty one patients fulfilling criteria of ABPA were evaluated in the present study...
  15. Latzin P, Hartl D, Regamey N, Frey U, Schoeni M, Casaulta C. Comparison of serum markers for allergic bronchopulmonary aspergillosis in cystic fibrosis. Eur Respir J. 2008;31:36-42 pubmed
    The diagnosis of allergic bronchopulmonary aspergillosis (ABPA) in cystic fibrosis (CF) is a challenge. Thymus- and activation-regulated chemokine (TARC) has recently been reported to play a role in ABPA...
  16. Deepak D, Panjabi C, Gudwani S, Chaudhary N, Shah A. Nasal septal perforation in a patient with allergic bronchopulmonary aspergillosis and rhinitis on long term corticosteroids. Asian Pac J Allergy Immunol. 2001;19:287-90 pubmed
    A 22-year-old male, referred to us as a case of multi-drug resistant tuberculosis was diagnosed as allergic bronchopulmonary aspergillosis (ABPA) after serological and computed tomography confirmation...
  17. Tonnel A, Tillie Leblond I. [Refractory asthma: diagnosing allergic bronchopulmonary aspergillosis]. Presse Med. 2008;37:161-6 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) results from a twofold mechanism: Th2-like hypersensitivity reaction and bronchial colonization by Aspergillus fumigatus...
  18. Ogasawara T, Iesato K, Okabe H, Murata K, Kominami S, Tomita K, et al. [A case of pleural effusion associated with allergic bronchopulmonary aspergillosis during a relapse of the disease]. Nihon Kokyuki Gakkai Zasshi. 2003;41:905-10 pubmed
    ..b>Allergic bronchopulmonary aspergillosis (ABPA) was diagnosed on the basis of the following findings: elevated serum IgE level, positive ..
  19. Shah A, Bhagat R, Panchal N, Jaggi O, Khan Z. Allergic bronchopulmonary aspergillosis with middle lobe syndrome and allergic Aspergillus sinusitis. Eur Respir J. 1993;6:917-8 pubmed
    ..Evaluation of the patient led to the diagnosis of concomitant allergic bronchopulmonary aspergillosis with allergic Aspergillus sinusitis, a rarely reported association.
  20. Blease K, Mehrad B, Lukacs N, Kunkel S, Standiford T, Hogaboam C. Antifungal and airway remodeling roles for murine monocyte chemoattractant protein-1/CCL2 during pulmonary exposure to Asperigillus fumigatus conidia. J Immunol. 2001;166:1832-42 pubmed
    ..These data suggest that MCP-1/CCL2 participates in the pulmonary antifungal and allergic responses to A. fumigatus conidia...
  21. Knutsen A, Noyes B, Warrier M, Consolino J. Allergic bronchopulmonary aspergillosis in a patient with cystic fibrosis: diagnostic criteria when the IgE level is less than 500 IU/mL. Ann Allergy Asthma Immunol. 2005;95:488-93 pubmed
    ..the Cystic Fibrosis Foundation developed a consensus report recommending diagnostic criteria for allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis that includes a serum IgE level greater than 500 IU/mL as ..
  22. Marchand E, Verellen Dumoulin C, Mairesse M, Delaunois L, Brancaleone P, Rahier J, et al. Frequency of cystic fibrosis transmembrane conductance regulator gene mutations and 5T allele in patients with allergic bronchopulmonary aspergillosis. Chest. 2001;119:762-7 pubmed
    To assess the frequency of cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in patients with allergic bronchopulmonary aspergillosis (ABPA).
  23. Wark P. Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment. Respir Med. 2004;98:915-23 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a complex condition that affects people with asthma and cystic fibrosis (CF)...
  24. Knutsen A, Bellone C, Kauffman H. Immunopathogenesis of allergic bronchopulmonary aspergillosis in cystic fibrosis. J Cyst Fibros. 2002;1:76-89 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity lung disease mediated by an allergic late-phase inflammatory response to Aspergillus fumigatus antigens...
  25. Agarwal R, Singh N, Gupta D. Pulmonary hypertension as a presenting manifestation of allergic bronchopulmonary aspergillosis. Indian J Chest Dis Allied Sci. 2009;51:37-40 pubmed
    ..Identification of the disease, in its early-stage, can prevent progression to bronchiectasis and fibrotic lung disease, and thus, patients can be saved from the morbidity related to end-stage disease...
  26. Allmers H, Huber H, Baur X. Two year follow-up of a garbage collector with allergic bronchopulmonary aspergillosis (ABPA). Am J Ind Med. 2000;37:438-42 pubmed
    ..Bronchial challenge testing with commercially available Aspergillus fumigatus extract resulted in an immediate-type asthmatic reaction. Two years later he was still symptomatic and antibodies persisted at lower levels...
  27. Shah A, Panjabi C. Allergic bronchopulmonary aspergillosis: a review of a disease with a worldwide distribution. J Asthma. 2002;39:273-89 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA), an immunologically mediated lung disease, occurs predominantly in patients with asthma...
  28. Greenberger P. Allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol. 2002;110:685-92 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) complicates asthma and cystic fibrosis. The survival factors in Aspergillus fumigatus that support saprophytic growth in bronchial mucus are not understood...
  29. Cockrill B, Hales C. Allergic bronchopulmonary aspergillosis. Annu Rev Med. 1999;50:303-16 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a syndrome seen in patients with asthma and cystic fibrosis. It is characterized by chronic colonization of the airways with a ubiquitous fungus, Aspergillus fumigatus...
  30. Stevens D, Schwartz H, Lee J, Moskovitz B, Jerome D, Catanzaro A, et al. A randomized trial of itraconazole in allergic bronchopulmonary aspergillosis. N Engl J Med. 2000;342:756-62 pubmed
    b>Allergic bronchopulmonary aspergillosis is a hypersensitivity disorder that can progress from an acute phase to chronic disease...
  31. Gupta K, Das A, Joshi K, Singh N, Aggarwal R, Prakash M. Aspergillus endocarditis in a known case of allergic bronchopulmonary aspergillosis: an autopsy report. Cardiovasc Pathol. 2010;19:e137-9 pubmed publisher
    ..This is an uncommon case of a 60-year-old asthmatic male who developed allergic bronchopulmonary aspergillosis during the course of his illness, and while receiving low dose oral steroids, he subsequently ..
  32. Kurup V, Raju R, Manickam P. Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis. Infect Immun. 2005;73:4381-4 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) results from the interactions of the Aspergillus allergens and immune system of the patients. We studied the gene expression profile in a mouse model of ABPA...
  33. Shah A, Kala J, Sahay S. Allergic bronchopulmonary aspergillosis with hilar adenopathy in a 42-month-old boy. Pediatr Pulmonol. 2007;42:747-8 pubmed
  34. Nikolaizik W, Weichel M, Blaser K, Crameri R. Intracutaneous tests with recombinant allergens in cystic fibrosis patients with allergic bronchopulmonary aspergillosis and Aspergillus allergy. Am J Respir Crit Care Med. 2002;165:916-21 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA), an intensive inflammatory reaction to Aspergillus fumigatus, can cause irreversible lung damage in patients with cystic fibrosis (CF)...
  35. Eaton T, Weiner Miller P, Garrett J, Cutting G. Cystic fibrosis transmembrane conductance regulator gene mutations: do they play a role in the aetiology of allergic bronchopulmonary aspergillosis?. Clin Exp Allergy. 2002;32:756-61 pubmed
    ..Previous work suggests that cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations may be implicated in the aetiology of allergic bronchopulmonary aspergilosis (ABPA)...
  36. Judson M, Stevens D. Current pharmacotherapy of allergic bronchopulmonary aspergillosis. Expert Opin Pharmacother. 2001;2:1065-71 pubmed
    ..carried out, the available data support the use of corticosteroids for acute exacerbations of allergic bronchopulmonary aspergillosis (ABPA)...
  37. Skov M, Høiby N, Koch C. Itraconazole treatment of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Allergy. 2002;57:723-8 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) in cystic fibrosis (CF) patients is a potentially fatal inflammatory disease due to the dual-type immune response provoked by the fungal antigens...
  38. Kauffman H. Immunopathogenesis of allergic bronchopulmonary aspergillosis and airway remodeling. Front Biosci. 2003;8:e190-6 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity lung disease clinically characterized by manifestation of wheezing, pulmonary infiltrates and bronchiectasis and fibrosis which afflicts asthmatic and cystic fibrosis (..
  39. Hogaboam C, Blease K, Schuh J. Cytokines and chemokines in allergic bronchopulmonary aspergillosis (ABPA) and experimental Aspergillus-induced allergic airway or asthmatic disease. Front Biosci. 2003;8:e147-56 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a devastating clinical disease that results from an aggressive pulmonary allergic response to the antigens released by colonizing Aspergillus fumigatus (A...
  40. Pasqualotto A, Powell G, Niven R, Denning D. The effects of antifungal therapy on severe asthma with fungal sensitization and allergic bronchopulmonary aspergillosis. Respirology. 2009;14:1121-7 pubmed publisher
    ..This study assessed the effect of antifungal therapy in patients with severe asthma with fungal sensitization (SAFS) and allergic bronchopulmonary aspergillosis (ABPA).
  41. Agarwal R, Gupta D, Aggarwal A, Saxena A, Saikia B, Chakrabarti A, et al. Clinical significance of decline in serum IgE levels in allergic bronchopulmonary aspergillosis. Respir Med. 2010;104:204-10 pubmed publisher
    The total serum IgE level is a marker of immunological activity in allergic bronchopulmonary aspergillosis (ABPA), and a 35% decline beyond six weeks is traditionally taken as criteria for remission...
  42. Erwin G, FitzGerald J. Case report: allergic bronchopulmonary aspergillosis and allergic fungal sinusitis successfully treated with voriconazole. J Asthma. 2007;44:891-5 pubmed
    b>Allergic bronchopulmonary aspergillosis and allergic fungal sinusitis are closely related disorders that rarely present in the same individual...
  43. Koehm S, Slavin R, Hutcheson P, Trejo T, David C, Bellone C. HLA-DRB1 alleles control allergic bronchopulmonary aspergillosis-like pulmonary responses in humanized transgenic mice. J Allergy Clin Immunol. 2007;120:570-7 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a lung hypersensitivity disease mediated in part by CD4(+) T(H)2 cells...
  44. Greenberger P. Allergic bronchopulmonary aspergillosis, allergic fungal sinusitis, and hypersensitivity pneumonitis. Clin Allergy Immunol. 2002;16:449-68 pubmed
  45. Gibson P, Wark P, Simpson J, Meldrum C, Meldrum S, Saltos N, et al. Induced sputum IL-8 gene expression, neutrophil influx and MMP-9 in allergic bronchopulmonary aspergillosis. Eur Respir J. 2003;21:582-8 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction to the fungus Aspergillus fumigatus, causing severe asthma that may progress to bronchiectasis...
  46. Ritz N, Ammann R, Casaulta Aebischer C, Schoeni Affolter F, Schoeni M. Risk factors for allergic bronchopulmonary aspergillosis and sensitisation to Aspergillus fumigatus in patients with cystic fibrosis. Eur J Pediatr. 2005;164:577-82 pubmed
    An increasing incidence of allergic bronchopulmonary aspergillosis (ABPA) as a complication in patients with cystic fibrosis (CF) is reported...
  47. Schwienbacher M, Israel L, Heesemann J, Ebel F. Asp f6, an Aspergillus allergen specifically recognized by IgE from patients with allergic bronchopulmonary aspergillosis, is differentially expressed during germination. Allergy. 2005;60:1430-5 pubmed
    Aspergillus fumigatus is a pathogenic mould causing allergic and invasive respiratory diseases. Allergic bronchopulmonary Aspergillosis (ABPA) is a severe pulmonary complication resulting from hypersensitivity to A. fumigatus proteins...
  48. Shah A, Panjabi C. Contemporaneous occurrence of allergic bronchopulmonary aspergillosis, allergic Aspergillus sinusitis, and aspergilloma. Ann Allergy Asthma Immunol. 2006;96:874-8 pubmed
    ..The coexistence of allergic bronchopulmonary aspergillosis (ABPA) with aspergilloma is uncommon, whereas concurrent ABPA and allergic Aspergillus sinusitis (..
  49. Agarwal R, Srinivas R, Jindal S. Allergic bronchopulmonary aspergillosis complicating chronic obstructive pulmonary disease. Mycoses. 2008;51:83-5 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a well recognised entity which complicates the course of 1-2% of patients with asthma and 2-15% of cystic fibrosis...
  50. Shah A, Maurya V, Panjabi C, Khanna P. Allergic bronchopulmonary aspergillosis without clinical asthma caused by Aspergillus niger. Allergy. 2004;59:236-7 pubmed
  51. Mussaffi H, Rivlin J, Shalit I, Ephros M, Blau H. Nontuberculous mycobacteria in cystic fibrosis associated with allergic bronchopulmonary aspergillosis and steroid therapy. Eur Respir J. 2005;25:324-8 pubmed
    ..3%) met the criteria for NTM pulmonary disease (five with M. abscessus). Five had allergic bronchopulmonary aspergillosis (ABPA) compared with one out of 133 patients without NTM disease...
  52. Barton R, Hobson R, Denton M, Peckham D, Brownlee K, Conway S, et al. Serologic diagnosis of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis through the detection of immunoglobulin G to Aspergillus fumigatus. Diagn Microbiol Infect Dis. 2008;62:287-91 pubmed publisher
    b>Allergic bronchopulmonary aspergillosis (ABPA) is seen in approximately 10% of patients with cystic fibrosis (CF) and can be difficult to diagnose...
  53. Agarwal R, Nath A, Aggarwal A, Gupta D, Chakrabarti A. Aspergillus hypersensitivity and allergic bronchopulmonary aspergillosis in patients with acute severe asthma in a respiratory intensive care unit in North India. Mycoses. 2010;53:138-43 pubmed publisher
    The prevalence of allergic bronchopulmonary aspergillosis (ABPA) in chronic asthma has been reported in various studies...
  54. Redmann S, Charles B. A rapid HPLC method with fluorometric detection for determination of plasma itraconazole and hydroxy-itraconazole concentrations in cystic fibrosis children with allergic bronchopulmonary aspergillosis. Biomed Chromatogr. 2006;20:343-8 pubmed
    ..method was demonstrated by measurement of itraconazole and hydroxy-itraconazole in plasma samples drawn from paediatric cystic fibrosis patients, who were prescribed itraconazole for treatment of allergic bronchopulmonary aspergillosis.
  55. Slavin R, Hutcheson P, Chauhan B, Bellone C. An overview of allergic bronchopulmonary aspergillosis with some new insights. Allergy Asthma Proc. 2004;25:395-9 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) occurs as a complication of bronchial asthma or cystic fibrosis (CF)...
  56. Ye F, Zhang N, Zhong N. [Clinical and pathological analysis of allergic bronchopulmonary aspergillosis in China]. Zhonghua Jie He He Hu Xi Za Zhi. 2009;32:434-8 pubmed
    To describe the clinical features and diagnosis of allergic bronchopulmonary aspergillosis (ABPA).
  57. Patterson K, Strek M. Allergic bronchopulmonary aspergillosis. Proc Am Thorac Soc. 2010;7:237-44 pubmed publisher
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a complex clinical entity that results from an allergic immune response to Aspergillus fumigatus, most often occurring in a patient with asthma or cystic fibrosis...
  58. Wark P, Hensley M, Saltos N, Boyle M, Toneguzzi R, Epid G, et al. Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: a randomized controlled trial. J Allergy Clin Immunol. 2003;111:952-7 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) complicates chronic asthma and results from hypersensitivity to the fungus Aspergillus fumigatu s, causing an intense systemic immune response and progressive lung damage.
  59. Skov M, McKay K, Koch C, Cooper P. Prevalence of allergic bronchopulmonary aspergillosis in cystic fibrosis in an area with a high frequency of atopy. Respir Med. 2005;99:887-93 pubmed
    ..Lower airway colonisation with Aspergillus fumigatus and the complicating hypersensitivity reaction allergic bronchopulmonary aspergillosis (ABPA) is well recognised in patients with cystic fibrosis (CF)...
  60. Suzuki K, Iwata S, Iwata H. Allergic bronchopulmonary aspergillosis in a 9-year-old boy. Eur J Pediatr. 2002;161:408-9 pubmed
  61. Moss R. Allergic bronchopulmonary aspergillosis. Clin Rev Allergy Immunol. 2002;23:87-104 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA) is a common complication of cystic fibrosis (CF), occurring in approximately 10% of patients and accompanying/accounting for approximately 10% of pulmonary exacerbations...
  62. Gibson P. Allergic bronchopulmonary aspergillosis. Semin Respir Crit Care Med. 2006;27:185-91 pubmed
    b>Allergic bronchopulmonary aspergillosis is an uncommon but serious respiratory condition characterized by chronic airway inflammation and airway damage resulting from persistent colonization by and sensitization to the fungus Aspergillus ..
  63. Crameri R, Hemmann S, Ismail C, Menz G, Blaser K. Disease-specific recombinant allergens for the diagnosis of allergic bronchopulmonary aspergillosis. Int Immunol. 1998;10:1211-6 pubmed
    b>Allergic bronchopulmonary aspergillosis (ABPA), a severe pulmonary complication caused by Aspergillus fumigatus, is considered a complex clinical syndrome with defined serological, pathological radiological and clinical features...