pleurisy

Summary

Summary: INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.

Top Publications

  1. Impellizzeri D, Esposito E, Mazzon E, Paterniti I, Di Paola R, Bramanti P, et al. The effects of oleuropein aglycone, an olive oil compound, in a mouse model of carrageenan-induced pleurisy. Clin Nutr. 2011;30:533-40 pubmed publisher
    ..The aim of this study was to investigate the effects of oleuropein aglycone, a hydrolysis product of oleuropein, in a mouse model of carrageenan-induced pleurisy.
  2. Meyns T, Van Steelant J, Rolly E, Dewulf J, Haesebrouck F, Maes D. A cross-sectional study of risk factors associated with pulmonary lesions in pigs at slaughter. Vet J. 2011;187:388-92 pubmed publisher
    ..001) and the frequent purchasing of pigs (P = 0.020). The findings of this study indicate that the prevalence of pleuritis and pneumonia remains high in Belgium and management factors are central to disease control...
  3. Costa M, Nihei J, Mengel J, Henriques M, Penido C. Requirement of L-selectin for gammadelta T lymphocyte activation and migration during allergic pleurisy: co-relation with eosinophil accumulation. Int Immunopharmacol. 2009;9:303-12 pubmed publisher
    ..Such results demonstrate that CD62L is crucial for the activation of gammadelta T cells in lymph nodes, for their migration into inflamed tissue and for the modulation of eosinophil influx during allergic response...
  4. Boschi E, Leite C, Saciura V, Caberlon E, Lunardelli A, Bitencourt S, et al. Anti-Inflammatory effects of low-level laser therapy (660 nm) in the early phase in carrageenan-induced pleurisy in rat. Lasers Surg Med. 2008;40:500-8 pubmed publisher
    In the classic model of pleurisy there is little evidence about the anti-inflammatory effects of low-level laser therapy (LLLT) as well the dosage characteristics, such as wavelength, total energy, number and pattern of treatment...
  5. Cuzzocrea S, Mazzon E, Di Paola R, Peli A, Bonato A, Britti D, et al. The role of the peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in the regulation of acute inflammation. J Leukoc Biol. 2006;79:999-1010 pubmed
    ..question, we used two animal models of acute inflammation (carrageenan-induced paw edema and carrageenan-induced pleurisy)...
  6. Lee H, Choi Y, Kim S, Lee T, Im E, Huh K, et al. [Familial infestation of Paragonimus westermani with peritonitis and pleurisy]. Korean J Gastroenterol. 2005;46:242-6 pubmed
    ..They were treated with praziquantel and their symptoms improved rapidly over 2 days. Both patients were asymptomatic at a follow-up visit 2 months later...
  7. Di Paola R, Mazzon E, Muià C, Genovese T, Menegazzi M, Zaffini R, et al. Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice. Respir Res. 2005;6:66 pubmed
    ..we investigate the effects of the green tea extract in an animal model of acute inflammation, carrageenan-induced pleurisy. We report here that green tea extract (given at 25 mg/kg i.p...
  8. Allegra M, Ianaro A, Tersigni M, Panza E, Tesoriere L, Livrea M. Indicaxanthin from cactus pear fruit exerts anti-inflammatory effects in carrageenin-induced rat pleurisy. J Nutr. 2014;144:185-92 pubmed publisher
    ..Miller) in a rat model of acute inflammation. Rat pleurisy was achieved by injection of 0...
  9. Kohmo S, Kijima T, Mori M, Minami T, Namba Y, Yano Y, et al. CXCL12 as a biological marker for the diagnosis of tuberculous pleurisy. Tuberculosis (Edinb). 2012;92:248-52 pubmed publisher
    ..To determine the clinical efficacy of CXCL12 as a diagnostic marker for tuberculous (TB) pleurisy, we measured CXCL12 concentration in pleural fluid and serum from patients with various etiologies...

More Information

Publications70

  1. Batinic Haberle I, Cuzzocrea S, Reboucas J, Ferrer Sueta G, Mazzon E, Di Paola R, et al. Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. Free Radic Biol Med. 2009;46:192-201 pubmed publisher
    ..In another model, carrageenan-induced pleurisy in mice, inflammation was evidenced by increased pleural fluid exudate and neutrophil infiltration and activation:..
  2. Goulart S, Moritz M, Lang K, Liz R, Schenkel E, Fröde T. Anti-inflammatory evaluation of Solidago chilensis Meyen in a murine model of pleurisy. J Ethnopharmacol. 2007;113:346-53 pubmed
    ..effects and the mechanism of action of the aqueous extracts obtained from rhizomes, leaves and inflorescences of Solidago chilensis in the mouse model of pleurisy. The extracts were prepared by infusion and were lyophilized.
  3. Mofredj A, Beldjoudi S, Farouj N. [Purulent pleurisy due to lactococcus lactis cremoris]. Rev Mal Respir. 2006;23:485-6 pubmed
  4. Crisafulli C, Mazzon E, Muià C, Bella P, Esposito E, Meli R, et al. Effects of combination of melatonin and dexamethasone on acute lung injury in a mice model of carrageenan-induced pleurisy. J Pineal Res. 2006;41:228-37 pubmed
    ..investigated the effects of combination therapy in animal models of acute lung inflammation (carrageenan-induced pleurisy)...
  5. Costa R, Fernandes E, Menezes de Lima O, Campos M, Calixto J. Effect of novel selective non-peptide kinin B(1) receptor antagonists on mouse pleurisy induced by carrageenan. Peptides. 2006;27:2967-75 pubmed
    ..receptor antagonists, the benzodiazepine antagonist and SSR240612, were evaluated in carrageenan-induced mouse pleurisy. The peptide R-715 (0.5 mg/kg, i.p.) and the non-peptide benzodiazepine (3 mg/kg, i.p...
  6. Lopes Martins R, Albertini R, Martins P, Bjordal J, Faria Neto H. Spontaneous effects of low-level laser therapy (650 nm) in acute inflammatory mouse pleurisy induced by carrageenan. Photomed Laser Surg. 2005;23:377-81 pubmed
    Our aim was to investigate the effect of low-level laser therapy (LLLT), 650-nm wavelength, on acute inflammatory pleurisy.
  7. Cakir E, Deniz O, Ozcan O, Tozkoparan E, Yaman H, Akgul E, et al. Pleural fluid and serum procalcitonin as diagnostic tools in tuberculous pleurisy. Clin Biochem. 2005;38:234-8 pubmed
    ..We investigated the use of procalcitonin (PCT) concentration in tuberculous pleuritis diagnosis...
  8. Kass S, Williams P, Reamy B. Pleurisy. Am Fam Physician. 2007;75:1357-64 pubmed
    ..When these other significant causes of pleuritic pain have been excluded, the diagnosis of pleurisy can be made. There are numerous causes of pleurisy, with viral pleurisy among the most common...
  9. Merialdi G, Dottori M, Bonilauri P, Luppi A, Gozio S, Pozzi P, et al. Survey of pleuritis and pulmonary lesions in pigs at abattoir with a focus on the extent of the condition and herd risk factors. Vet J. 2012;193:234-9 pubmed publisher
    ..Vaccination of weaners at 3-5 weeks of age against PRRS using a modified live vaccine was associated with a reduction in the percentage of cranioventral pulmonary consolidation (EP-like lesions)...
  10. Eros G, Varga G, Varadi R, Czobel M, Kaszaki J, Ghyczy M, et al. Anti-inflammatory action of a phosphatidylcholine, phosphatidylethanolamine and N-acylphosphatidylethanolamine-enriched diet in carrageenan-induced pleurisy. Eur Surg Res. 2009;42:40-8 pubmed publisher
    ..We hypothesized that an increased dietary input of PC, PE and NAPE may interfere with leukocyte reactions and thus decreases the inflammatory activation...
  11. Nardi G, Siqueira Junior J, Delle Monache F, Pizzolatti M, Ckless K, Ribeiro do Valle R. Antioxidant and anti-inflammatory effects of products from Croton celtidifolius Bailon on carrageenan-induced pleurisy in rats. Phytomedicine. 2007;14:115-22 pubmed
    ..superoxide dismutase (SOD) activity and superoxide anion production) parameters in carrageenan-induced pleurisy in rats. NO production was also measured by nitrite/nitrate levels...
  12. Sousa L, Carmo A, Rezende B, Lopes F, Silva D, Alessandri A, et al. Cyclic AMP enhances resolution of allergic pleurisy by promoting inflammatory cell apoptosis via inhibition of PI3K/Akt and NF-kappaB. Biochem Pharmacol. 2009;78:396-405 pubmed publisher
    ..underlying the ability of cAMP elevating agents to resolve eosinophilic inflammation in a model of allergic pleurisy in mice...
  13. Lunardelli A, Leite C, Pires M, de Oliveira J. Extract of the bristles of Dirphia sp. increases nitric oxide in a rat pleurisy model. Inflamm Res. 2006;55:129-35 pubmed
    ..In the present study we assessed the inflammatory potential of venom obtained from caterpillar genus Dirphia in an acute model of lung injury...
  14. Di Paola R, Crisafulli C, Mazzon E, Esposito E, Paterniti I, Galuppo M, et al. GW0742, a high-affinity PPAR -beta/delta agonist, inhibits acute lung injury in mice. Shock. 2010;33:426-35 pubmed publisher
    ..the effects of a high-affinity PPAR-beta/delta agonist, GW0742, in a mouse model of carrageenan (CAR)-induced pleurisy. Injection of CAR into the pleural cavity of mice elicited an acute inflammatory response characterized by ..
  15. Shu C, Lee L, Wang J, Chien Y, Wang J, Yu C. Non-tuberculous mycobacterial pleurisy: an 8-year single-centre experience in Taiwan. Int J Tuberc Lung Dis. 2010;14:635-41, 4 p following 641 pubmed
    To investigate the clinical characteristics and outcomes of patients with pleurisy due to non-tuberculous mycobacteria (NTM), which are currently unclear.
  16. Dalmarco E, Budni P, Parisotto E, Wilhelm Filho D, Fröde T. Antioxidant effects of mycophenolate mofetil in a murine pleurisy model. Transpl Immunol. 2009;22:12-7 pubmed publisher
    ..and exudation, as well as myeloperoxidase and some antioxidant enzyme activities using carrageenan-induced pleurisy in mice. Our results showed that MMF significantly decreased leukocyte influx (P<0.01), exudation (P<0...
  17. Yoshida H, Hasegawa R, Hayashi H, Irie Y. Imidapril-induced eosinophilic pleurisy. Case report and review of the literature. Respiration. 2005;72:423-6 pubmed
    We describe an unusual case of a patient with eosinophilic pleurisy associated with long-term administration of imidapril, an angiotensin-converting enzyme inhibitor (ACEI)...
  18. Gomides L, Duarte I, Ferreira R, Perez A, Francischi J, Klein A. Proteinase-activated receptor-4 plays a major role in the recruitment of neutrophils induced by trypsin or carrageenan during pleurisy in mice. Pharmacology. 2012;89:275-82 pubmed publisher
  19. Moriya Y, Sugawara T, Arai M, Tsuda Y, Uchida K, Noguchi T, et al. Bilateral massive bloody pleurisy complicated by angiosarcoma. Intern Med. 2007;46:125-8 pubmed
    We report a case of angiosarcoma complicated by bilateral massive bloody pleurisy (hematocrit of 7.2%) in an 83-year-old woman. An autopsy revealed hemorrhagic tumors infiltrating both the diaphragm and serosal surface of the peritoneum...
  20. Niwa T, Nakamura A, Kato T, Kutsuna T, Katou K, Morita H, et al. Pharmacokinetic study of pleural fluid penetration of carbapenem antibiotic agents in chemical pleurisy. Respir Med. 2006;100:324-31 pubmed
    ..agents [imipenem (IPM), panipenem (PAPM), meropenem (MEPM), and biapenem (BIPM)] using an experimental rabbit pleuritis model to clarify the usefulness of the carbapenem agents for the treatment of bacterial pleurisy or pyothorax.
  21. Dagnra A, Gbadoe A, Edorh T, Prince David M, Tidjani O, Sadzo D. [Incidence and impact of HIV infection among patients with bacterial pleurisy in Lomé (Togo)]. Med Mal Infect. 2004;34:216-20 pubmed
    ..hospital in Lomé (Togo) to determine the incidence and the impact of HIV among patients with bacterial pleurisy. Two hundred cases of bacterial pleurisy were consecutively included over 17 months...
  22. Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Ndengele M, Salvemini D. Superoxide-related signaling cascade mediates nuclear factor-kappaB activation in acute inflammation. Antioxid Redox Signal. 2004;6:699-704 pubmed
    ..These data confirm that M40403 exerts a potent antiinflammatory activity and clearly demonstrate that the reduction of the inflammatory process is associated with modification of the activation of signal transduction pathways...
  23. Pozzatti P, dos Reis G, Pereira D, Heller M, Micke G, Horst H, et al. Esenbeckia leiocarpa Engl. inhibits inflammation in a carrageenan-induced murine model of pleurisy. J Pharm Pharmacol. 2011;63:1091-102 pubmed publisher
    ..The aim of this study was to investigate the anti-inflammatory effects of the crude hydroalcoholic extract (CHE) isolated from Esenbeckia leiocarpa Engl., and fractions and subfractions derived from it...
  24. Busnardo T, Padoani C, Mora T, Biavatti M, Fröde T, Burger C, et al. Anti-inflammatory evaluation of Coronopus didymus in the pleurisy and paw oedema models in mice. J Ethnopharmacol. 2010;128:519-25 pubmed publisher
    ..The aim of this study was: to investigate the anti-inflammatory effect of hydroalcoholic extract obtained from the leaves of CD following the traditional procedure...
  25. Ceccarelli M, Bani D, Cinci L, Nistri S, Uliva C, Ragazzo E, et al. Anti-inflammatory effects of low molecular weight heparin derivative in a rat model of carrageenan-induced pleurisy. J Cell Mol Med. 2009;13:2704-12 pubmed publisher
    ..weight, has marked anti-inflammatory effects in a rat model of acute inflammation, the carrageenan-induced pleurisy, commonly used to test NSAID efficacy. A 30-min. pre-treatment with K5NOSepiLMW (0.1, 0.5 and 1 mg/kg b.wt...
  26. Bandeira Melo C, Bonavita A, Diaz B, E Silva P, Carvalho V, Jose P, et al. A novel effect for annexin 1-derived peptide ac2-26: reduction of allergic inflammation in the rat. J Pharmacol Exp Ther. 2005;313:1416-22 pubmed
    ..In the current study, we report the effectiveness of the peptide Ac2-26 as an antiallergic tool in a model of rat pleurisy and provide indication for some of the mechanisms involved...
  27. Sakaguchi Y, Shirahase H, Kunishiro K, Ichikawa A, Kanda M, Uehara Y. Effect of combination of nitric oxide synthase and cyclooxygenase inhibitors on carrageenan-induced pleurisy in rats. Life Sci. 2006;79:442-7 pubmed
    ..IND), a non-selective COX inhibitor and a combination of these agents (L-NAME+IND) on carrageenan-induced pleurisy in rats...
  28. Fraile L, Alegre A, López Jiménez R, Nofrarias M, Segales J. Risk factors associated with pleuritis and cranio-ventral pulmonary consolidation in slaughter-aged pigs. Vet J. 2010;184:326-33 pubmed publisher
    ..59) that cranio-ventral pulmonary consolidation lesions (EP-like lesions) were affected by the type of farm ventilation, the presence of respiratory symptoms during the fattening period and Mhyo and SIV H1N2 herd seroprevalence...
  29. Kawanami T, Fukuda K, Yatera K, Kido M, Mukae H, Taniguchi H. A higher significance of anaerobes: the clone library analysis of bacterial pleurisy. Chest. 2011;139:600-608 pubmed publisher
    ..The aims of this study were to evaluate bacterial etiologies of bacterial pleurisy using a cultivation-independent method.
  30. Pereira R, Medeiros Y, Fröde T. Antiinflammatory effects of Tacrolimus in a mouse model of pleurisy. Transpl Immunol. 2006;16:105-11 pubmed
    ..Tacrolimus is an antibiotic macrolide with immunosuppressant properties isolated from Streptomyces tsukubaensis...
  31. Sjolund M, Zoric M, Persson M, Karlsson G, Wallgren P. Disease patterns and immune responses in the offspring to sows with high or low antibody levels to Actinobacillus pleuropneumoniae serotype 2. Res Vet Sci. 2011;91:25-31 pubmed publisher
    ..These piglets will also mount a higher antibody response when later infected, indicating a heritability of the humoral immune response...
  32. Budak F, Uzaslan E, Cangur S, Goral G, Oral H. Increased pleural soluble fas ligand (sFasL) levels in tuberculosis pleurisy and its relation with T-helper type 1 cytokines. Lung. 2008;186:337-43 pubmed publisher
    Tuberculosis (TB) pleurisy is accepted to be the best model for evaluating the local protective cellular immune response to Mycobacterium tuberculosis (MTB) since it can be spontaneously self-cured...
  33. Dalmarco E, Medeiros Y, Fröde T. Cyclosporin A inhibits CD11a/CD18 adhesion molecules due to inhibition of TNFalpha and IL-1 beta levels in the mouse model of pleurisy induced by carrageenan. Cell Adh Migr. 2008;2:231-5 pubmed
    The mouse model of pleurisy induced by carrageenan is characterized by a significant enhancement of cell migration due to neutrophils 4 h after pleurisy induction...
  34. Buss Z, Medeiros Y, Fröde T. PPAR-gamma agonist rosiglitazone attenuates the inflammation caused by carrageenan in the mouse model of pleurisy. Inflammation. 2012;35:280-8 pubmed publisher
    The aim of this study was to investigate the anti-inflammatory efficacy of rosiglitazone (ROSI) in a pleurisy model of carrageenan-induced inflammation...
  35. Impellizzeri D, Di Paola R, Esposito E, Mazzon E, Paterniti I, Melani A, et al. CGS 21680, an agonist of the adenosine (A2A) receptor, decreases acute lung inflammation. Eur J Pharmacol. 2011;668:305-16 pubmed publisher
    ..1mg/kgi.p.), an agonist of the adenosine (A(2A)) receptor, in a mouse model of carrageenan-induced pleurisy. Injection of carrageenan into the pleural cavity of mice elicited an acute inflammatory response characterised ..
  36. Suminoe A, Matsuzaki A, Koga Y, Kusuhara K, Hara T. Human herpesvirus 6 (HHV-6)-associated pleurisy after unrelated cord blood transplantation in children with chemotherapy-resistant malignant Lymphoma. J Pediatr Hematol Oncol. 2007;29:709-12 pubmed
    ..Both of them suffered from pleurisy with and without interstitial pneumonitis after transplantation...
  37. Cleveland Nielsen A, Nielsen E, Ersbøll A. Chronic pleuritis in Danish slaughter pig herds. Prev Vet Med. 2002;55:121-35 pubmed
    ..Two factors protected against CP: feeding with only dry feed and practising all-in-all-out production. ..
  38. Yamada Y, Nakamura A, Hosoda M, Kato T, Asano T, Tonegawa K, et al. Cytokines in pleural liquid for diagnosis of tuberculous pleurisy. Respir Med. 2001;95:577-81 pubmed
    ..deaminase (ADA) in pleural liquid has been considered as a supplemental diagnostic marker for tuberculous pleurisy. However, this is complicated by false-positives and -negatives...
  39. Hayashi I, Amano H, Ishihara K, Kumagai Y, Yoshimura H, Majima M. The role of kinin B1 in the plasma extravasation of carrageenin-induced pleurisy. Life Sci. 2002;70:937-49 pubmed
    ..of des-Arg9-bradykinin (des-Arg9-BK) and kinin B1 receptor in the plasma extravasation of rat carrageenin-induced pleurisy was investigated employing B1 receptor agonist and antagonists and kininogen-deficient rats...
  40. Cuzzocrea S, Mazzon E, Sautebin L, Dugo L, Serraino I, De Sarro A, et al. Protective effects of Celecoxib on lung injury and red blood cells modification induced by carrageenan in the rat. Biochem Pharmacol. 2002;63:785-95 pubmed
    ..Therefore, selective inhibitor of COX-2 such as Celecoxib, offers a therapeutic approach for the management of various inflammatory diseases. ..
  41. Salvemini D, Mazzon E, Dugo L, Riley D, Serraino I, Caputi A, et al. Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403. Br J Pharmacol. 2001;132:815-27 pubmed
    ..For this purpose, the pharmacological profile of M40403 was evaluated in carrageenan-induced pleurisy. 3...
  42. Enøe C, Mousing J, Schirmer A, Willeberg P. Infectious and rearing-system related risk factors for chronic pleuritis in slaughter pigs. Prev Vet Med. 2002;54:337-49 pubmed
    ..In SPF herds, farrow-to-finish as opposed to finishing herds was associated with 47% of the occurrence of CP. Seropositivity for MYC was associated with 33% (39%) of the occurrence of CP in herds with a size > (< or =) 1,500 pigs. ..
  43. Alexiou Daniel S, Tea A, Ilonidis G, Antoniadis A. A case of pleurisy associated with antibodies to Rickettsia conorii. Clin Microbiol Infect. 2003;9:437-40 pubmed
    ..Conorii infection, which concerns a farmer with clinical, radiological and cytological findings of pleurisy without evidence of malignancy. An elevated antibody titre for R...
  44. Cuzzocrea S, McDonald M, Filipe H, Costantino G, Mazzon E, Santagati S, et al. Effects of tempol, a membrane-permeable radical scavenger, in a rodent model of carrageenan-induced pleurisy. Eur J Pharmacol. 2000;390:209-22 pubmed
    ..the effects of tempol, a membrane-permeable radical scavenger, in rats subjected to carrageenan-induced pleurisy. Treatment of rats with tempol (10, 30, or 100 mg/kg 15 min prior to carrageenan) attenuated the pleural ..
  45. Cuzzocrea S, Sautebin L, De Sarro G, Costantino G, Rombola L, Mazzon E, et al. Role of IL-6 in the pleurisy and lung injury caused by carrageenan. J Immunol. 1999;163:5094-104 pubmed
    ..Taken together, our results clearly demonstrate that IL-6KO mice are more resistant to the acute inflammation of the lung caused by carrageenan injection into the pleural space than the corresponding WT mice...
  46. Watarai M, Yazawa M, Yamanda K, Yamamoto H, Yamazaki Y. Pulmonary sarcoidosis with associated bloody pleurisy. Intern Med. 2002;41:1021-3 pubmed
    ..Serum angiotensin-II-converting enzyme and lysozyme levels were elevated. Since thoracentesis indicated bloody pleurisy, video-assisted thoracoscopy was performed and revealed multiple white nodules on both the visceral and parietal ..
  47. Fröde T, Souza G, Calixto J. The effects of IL-6 and IL-10 and their specific antibodies in the acute inflammatory responses induced by carrageenan in the mouse model of pleurisy. Cytokine. 2002;17:149-56 pubmed
    ..total and differential leukocyte influx, but significantly increased exudation according to assessment 4 h after pleurisy induction by Cg (P<0.01)...
  48. Kunter E, Cerrahoglu K, Ilvan A, Isitmangil T, Turken O, Okutan O, et al. The value of pleural fluid anti-A60 IgM in BCG-vaccinated tuberculous pleurisy patients. Clin Microbiol Infect. 2003;9:212-20 pubmed
    To determine if detection of IgM and IgG antibodies against mycobacterial antigen A60, together with the Mantoux tuberculin skin test (TST), could be used in the diagnosis of tuberculous pleurisy (TP) in BCG-vaccinated cases.
  49. Cuzzocrea S, Costantino G, Mazzon E, Caputi A. Beneficial effects of raxofelast (IRFI 016), a new hydrophilic vitamin E-like antioxidant, in carrageenan-induced pleurisy. Br J Pharmacol. 1999;126:407-14 pubmed
    ..of raxofelast, a new hydrophilic vitamin E-like antioxidant agent, in rats subjected to carrageenan-induced pleurisy. 2...
  50. Gilroy D, Colville Nash P, McMaster S, Sawatzky D, Willoughby D, Lawrence T. Inducible cyclooxygenase-derived 15-deoxy(Delta)12-14PGJ2 brings about acute inflammatory resolution in rat pleurisy by inducing neutrophil and macrophage apoptosis. FASEB J. 2003;17:2269-71 pubmed
    ..In an acute pleurisy, polymorphonuclear leukocytes (PMNs) were found to predominate at the onset of the lesion but decreased in number ..
  51. Tomlinson A, Appleton I, Moore A, Gilroy D, Willis D, Mitchell J, et al. Cyclo-oxygenase and nitric oxide synthase isoforms in rat carrageenin-induced pleurisy. Br J Pharmacol. 1994;113:693-8 pubmed
    ..of cyclo-oxygenase (COX) and nitric oxide synthase (NOS) isoforms were determined in the rat carrageenin-induced pleurisy model of acute inflammation. 2...
  52. Edamitsu S, Matsukawa A, Ohkawara S, Takagi K, Nariuchi H, Yoshinaga M. Role of TNF alpha, IL-1, and IL-1ra in the mediation of leukocyte infiltration and increased vascular permeability in rabbits with LPS-induced pleurisy. Clin Immunol Immunopathol. 1995;75:68-74 pubmed
    ..role in the mediation of leukocyte infiltration and increased vascular permeability in rabbits with LPS-induced pleurisy. The leukocyte infiltration was largely mediated by both TNF alpha and IL-1 and could be divided into at least ..
  53. Pinho V, Oliveira S, Souza D, Vasconcelos D, Alessandri A, Lukacs N, et al. The role of CCL22 (MDC) for the recruitment of eosinophils during allergic pleurisy in mice. J Leukoc Biol. 2003;73:356-62 pubmed
    ..However, in an allergic pleurisy model, an anti-CCL22 polyclonal antibody given during sensitization or before challenge had no significant effect ..
  54. Cuzzocrea S, Costantino G, Mazzon E, Caputi A. Regulation of prostaglandin production in carrageenan-induced pleurisy by melatonin. J Pineal Res. 1999;27:9-14 pubmed
    ..the production of the inflammatory mediator prostaglandins in a model of acute inflammation, carrageenan-induced pleurisy, where prostaglandins are known to play a crucial role. The results show that melatonin (12...
  55. Ianaro A, Ialenti A, Maffia P, Pisano B, Di Rosa M. Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. FEBS Lett. 2001;508:61-6 pubmed
    In this study, using rat carrageenin-induced pleurisy, we found that treatment of rats with either indomethacin or NS-398 suppressed the pleurisy at 2 h but significantly exacerbated this reaction at 48 h...
  56. Monguilhott Dalmarco E, Fröde T, Medeiros Y. Additional evidence of acute anti-inflammatory effects of cyclosporin A in a murine model of pleurisy. Transpl Immunol. 2004;12:151-7 pubmed
    ..It is well known that cyclosporin A (CsA) exhibits important anti-inflammatory effects, besides its immunosuppressive activity. However, the mechanisms by which CsA exerts these effects remain unclear...
  57. Makino J, Yoshiyama Y, Kanke M, Kamata M, Ozawa S, Maruyama H, et al. [Pharmacokinetic study of penetration of meropenem into pleural effusion in patients with pleurisy]. Jpn J Antibiot. 2002;55:77-88 pubmed
    Complication by secondary infection is observed in not only bacterial pleurisy but also other pleurisy, and the appropriate administration of antibacterial agents is necessary...
  58. Murai N, Nagai K, Fujisawa H, Hatanaka K, Kawamura M, Harada Y. Concurrent evolution and resolution in an acute inflammatory model of rat carrageenin-induced pleurisy. J Leukoc Biol. 2003;73:456-63 pubmed
    ..course of neutrophil apoptosis and the following ingestion by mononuclear leukocytes in rat carrageenin-induced pleurisy, detecting DNA fragmentation by the deoxyuridine triphosphate-biotin nick-end labeling (TUNEL) method, by ..
  59. Cuzzocrea S, Mazzon E, Sautebin L, Serraino I, Dugo L, Calabro G, et al. The protective role of endogenous estrogens in carrageenan-induced lung injury in the rat. Mol Med. 2001;7:478-87 pubmed
    ..Here we investigate the effects of endogenous estrogens in rats subjected to carrageenan-induced pleurisy.
  60. Fröde T, Medeiros Y. Myeloperoxidase and adenosine-deaminase levels in the pleural fluid leakage induced by carrageenan in the mouse model of pleurisy. Mediators Inflamm. 2001;10:223-7 pubmed
    ..Although myeloperoxidase (MPO) and adenosine-deaminase (ADA) levels are markers of activated leukocytes, both enzymes have not been currently addressed in inflammation models...
  61. Fröde T, Souza G, Calixto J. The modulatory role played by TNF-alpha and IL-1 beta in the inflammatory responses induced by carrageenan in the mouse model of pleurisy. Cytokine. 2001;13:162-8 pubmed
    ..total and differential cell migration at 4 h, while having little or no effect on the late (48 h) phase of the Cg pleurisy. These findings extend previous results and demonstrate that the pro-inflammatory cytokines TNF-alpha and IL-..