pleural empyema

Summary

Summary: Suppurative inflammation of the pleural space.

Top Publications

  1. Shen Y, Hwang K, Niu C. Complicated parapneumonic effusion and empyema in children. J Microbiol Immunol Infect. 2006;39:483-8 pubmed
  2. Avansino J, Goldman B, Sawin R, Flum D. Primary operative versus nonoperative therapy for pediatric empyema: a meta-analysis. Pediatrics. 2005;115:1652-9 pubmed
    ..The optimal treatment of children with empyema remains controversial. The purpose of this review was to compare reported results of nonoperative and primary operative therapy for the treatment of pediatric empyema...
  3. Spencer D, Iqbal S, Hasan A, Hamilton L. Empyema thoracis is still increasing in UK children. BMJ. 2006;332:1333 pubmed
  4. Arancibia M, Vega Briceño L, Pizarro M, Pulgar D, Holmgren N, Bertrand P, et al. [Empyema and pleural effusion in children]. Rev Chilena Infectol. 2007;24:454-61 pubmed publisher
    b>Pleural empyema (PE) is a serious complication of community-acquired pneumonia (CAP).
  5. Lahti E, Mertsola J, Kontiokari T, Eerola E, Ruuskanen O, Jalava J. Pneumolysin polymerase chain reaction for diagnosis of pneumococcal pneumonia and empyema in children. Eur J Clin Microbiol Infect Dis. 2006;25:783-9 pubmed
    ..In the evaluation of blood samples, blood culture remains the superior method for the diagnosis of bacteremic pneumococcal disease...
  6. Macedo M, Meyer K, Oliveira T. Necrotizing pneumonia in children submitted to thoracoscopy due to pleural empyema: incidence, treatment and clinical evolution. J Bras Pneumol. 2010;36:301-5 pubmed
    ..To assess the incidence of necrotizing pneumonia (NP) in children submitted to thoracoscopy, comparing patients with and without NP in terms of the presentation and clinical evolution...
  7. Wurnig P, Wittmer V, Pridun N, Hollaus P. Video-assisted thoracic surgery for pleural empyema. Ann Thorac Surg. 2006;81:309-13 pubmed
    ..After we gained considerable experience with video-assisted thoracic surgery (VATS) and became familiar with its advantages, we started to use it for the treatment of thoracic empyema...
  8. Byington C, Korgenski K, Daly J, Ampofo K, Pavia A, Mason E. Impact of the pneumococcal conjugate vaccine on pneumococcal parapneumonic empyema. Pediatr Infect Dis J. 2006;25:250-4 pubmed
    ..Our objective was to describe the temporal trends in PPE in Utah before and after the availability of the 7-valent pneumococcal conjugate vaccine (PCV-7)...
  9. Le Monnier A, Carbonnelle E, Zahar J, Le Bourgeois M, Abachin E, Quesne G, et al. Microbiological diagnosis of empyema in children: comparative evaluations by culture, polymerase chain reaction, and pneumococcal antigen detection in pleural fluids. Clin Infect Dis. 2006;42:1135-40 pubmed
    b>Pleural empyema is an increasingly reported complication of pneumonia in children. Microbiological diagnostic tests for empyema by culture frequently have false-negative results due to previous administration of antibiotics...

More Information

Publications68

  1. Fletcher M, Leeming J, Cartwright K, Finn A. Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine. Pediatr Infect Dis J. 2006;25:559-60 pubmed
    During 2003-2004, locally presenting pleural empyema cases in children increased 3-fold...
  2. Ploton C, Freydiere A, Benito Y, Bendridi N, Mazzocchi C, Bellon G, et al. Streptococcus pneumoniae thoracic empyema in children: rapid diagnosis by using the Binax NOW immunochromatographic membrane test in pleural fluids. Pathol Biol (Paris). 2006;54:498-501 pubmed
    ..To evaluate an immunochromatographic membrane test for Streptococcus pneumoniae antigen (Binax NOW, Inverness medical France) applied to pleural fluid samples...
  3. Leung C, Chang Y. Video-assisted thoracoscopic surgery in a 1-month-old infant with pleural empyema. J Formos Med Assoc. 2006;105:936-40 pubmed
    b>Pleural empyema is a frequent complication of bacterial pneumonia in childhood but is rare in neonates...
  4. Sonnappa S, Jaffe A. Treatment approaches for empyema in children. Paediatr Respir Rev. 2007;8:164-70 pubmed
  5. Matzi V, Lindenmann J, Porubsky C, Neuboeck N, Maier A, Smolle Juettner F. Intrathoracic insertion of the VAC device in a case of pleural empyema 20 years after pneumonectomy. Ann Thorac Surg. 2007;84:1762-4 pubmed
    We report a 72-year-old man suffering from pleural empyema after pneumonectomy due to nonsmall cell lung cancer 20 years previously. Insufficiency of the bronchial stump was ruled out by bronchoscopy and bronchography...
  6. Sahn S. Diagnosis and management of parapneumonic effusions and empyema. Clin Infect Dis. 2007;45:1480-6 pubmed
    ..Fibrinolytics are most likely to be effective during the early fibrinolytic stage and may make surgical drainage unnecessary. If pleural space drainage is ineffective, video-assisted thoracic surgery should be performed without delay...
  7. Roxburgh C, Youngson G, Townend J, Turner S. Trends in pneumonia and empyema in Scottish children in the past 25 years. Arch Dis Child. 2008;93:316-8 pubmed
    ..The incidence of childhood empyema, a complication of pneumonia, is increasing, and the underlying mechanisms are not understood. Whether a rise in pneumonia incidence could account for the increase in empyema remains to be seen...
  8. Liapakis I, Light R, Pitiakoudis M, Karayiannakis A, Giamarellos Bourboulis E, Ismailos G, et al. Penetration of clarithromycin in experimental pleural empyema model fluid. Respiration. 2005;72:296-300 pubmed
    ..The degree of penetration of clarithromycin into the pleural fluid has not been studied...
  9. Bekri H, Cohen R, Varon E, Madhi F, Gire R, Guillot F, et al. [Streptococcus pneumoniae serotypes involved in children with pleural empyemas in France]. Arch Pediatr. 2007;14:239-43 pubmed
    ..Potential prevention of pleural empyemas by the heptavalent pneumococcal conjugate vaccine is dependent on adequation between specific pneumococcal serogroups present in vaccine and those responsible for empyemas...
  10. Finley C, Clifton J, FitzGerald J, Yee J. Empyema: an increasing concern in Canada. Can Respir J. 2008;15:85-9 pubmed
    ..Empyema is a suppurative infection of the pleural space. Without prompt treatment, it can result in significant hospital stays, more invasive treatments as it progresses, and substantial morbidity and mortality...
  11. Chapman S, Khor C, Vannberg F, Frodsham A, Walley A, Maskell N, et al. IkappaB genetic polymorphisms and invasive pneumococcal disease. Am J Respir Crit Care Med. 2007;176:181-7 pubmed
    ..Rare NFKBIA mutations cause immunodeficiency with severe bacterial infection, raising the possibility that common IkappaB gene polymorphisms confer susceptibility to common bacterial disease...
  12. Chen S, Chen W, Hsu W, Yu Y, Shih C. Role of pleural fluid C-reactive protein concentration in discriminating uncomplicated parapneumonic pleural effusions from complicated parapneumonic effusion and empyema. Lung. 2006;184:141-5 pubmed
    ..97/1,00/0.95. This study suggests that measurement of pleural CRP can be useful in the workup of patients with a parapneumonic effusion in order to differentiate CPPE from UPPE...
  13. Cardillo G, Carleo F, Carbone L, Di Martino M, Salvadori L, Petrella L, et al. Chronic postpneumonic pleural empyema: comparative merits of thoracoscopic versus open decortication. Eur J Cardiothorac Surg. 2009;36:914-8 pubmed publisher
    We seek to evaluate the comparative merits of thoracoscopic versus open decortication in the surgical management of patients with chronic postpneumonic pleural empyema.
  14. Sonnappa S, Cohen G, Owens C, van Doorn C, Cairns J, Stanojevic S, et al. Comparison of urokinase and video-assisted thoracoscopic surgery for treatment of childhood empyema. Am J Respir Crit Care Med. 2006;174:221-7 pubmed
    ..Despite increasing incidence and morbidity, little evidence exists to inform the best management approach in childhood empyema...
  15. Vucicevic Z, Sharma M, Miklic S, Ferencic Z. Multiloculated pleural empyema following acupuncture. Infection. 2005;33:297-8 pubmed
  16. Clark J. Microbiology and management of pleural empyema. Adv Exp Med Biol. 2009;634:61-8 pubmed
    ..Serotype 1 pneumococcus is frequently implicated and the reasons for an apparent increase in incidence remain unclear. Management requires antibiotics and removal of pus either by fibrinolysis or primary drainage...
  17. Solaini L, Prusciano F, Bagioni P. Video-assisted thoracic surgery in the treatment of pleural empyema. Surg Endosc. 2007;21:280-4 pubmed
    The use of video-assisted thoracic surgery (VATS) in the treatment of pleural empyema has been proposed since the early 1990s, but among surgeons, its use varies considerably, and the results are discordant...
  18. Obando I, Arroyo L, Sanchez Tatay D, Moreno D, Hausdorff W, Brueggemann A. Molecular typing of pneumococci causing parapneumonic empyema in Spanish children using multilocus sequence typing directly on pleural fluid samples. Pediatr Infect Dis J. 2006;25:962-3 pubmed
  19. Cascio A, Barone M, Micali V, Iaria C, Delfino D, David A, et al. On a fatal case of Candida krusei pleural empyema in a pregnant woman with spontaneous esophagus perforation. Mycopathologia. 2010;169:451-5 pubmed publisher
    ..The case is contextualized among similar cases found through a PubMed search...
  20. Engum S. Minimal access thoracic surgery in the pediatric population. Semin Pediatr Surg. 2007;16:14-26 pubmed
    ..The role of the robot in pediatric thoracoscopy is still in the early stages of definition...
  21. Griffiths A, Massie J. Pleural empyema in a 14-year-old adolescent with cystic fibrosis. J Paediatr Child Health. 2006;42:396-7 pubmed
  22. Hernández Pérez J, Rodríguez Suárez P, Freixinet Gilart J. [Pleural empyema secondary to pyonephrosis]. Arch Bronconeumol. 2008;44:285 pubmed
  23. Cremonesini D, Thomson A. How should we manage empyema: antibiotics alone, fibrinolytics, or primary video-assisted thoracoscopic surgery (VATS)?. Semin Respir Crit Care Med. 2007;28:322-32 pubmed
    ..Both of these treatments result in shorter hospital stay and fewer complications than the conservative approach. In this review we will appraise the evidence for all three treatments and consider which treatment is optimal in children...
  24. Schiza S, Siafakas N. Clinical presentation and management of empyema, lung abscess and pleural effusion. Curr Opin Pulm Med. 2006;12:205-11 pubmed
    ..Pleural effusions, lung abscess and empyema remain a commonly encountered clinical problem and a significant source of morbidity. The aim of this review is to summarize recent developments with emphasis on controlled trials...
  25. Chan D, Sihoe A, Chan S, Tsang D, Fang B, Lee T, et al. Surgical treatment for empyema thoracis: is video-assisted thoracic surgery "better" than thoracotomy?. Ann Thorac Surg. 2007;84:225-31 pubmed
    ..This study compares the radiologic and functional outcomes of decortication using the two approaches...
  26. Lahti E, Peltola V, Virkki R, Alanen M, Ruuskanen O. Development of parapneumonic empyema in children. Acta Paediatr. 2007;96:1686-92 pubmed
    ..The aim of the study was to find clinical predictors for parapneumonic empyema in children...
  27. Barbato A, Panizzolo C, Monciotti C, Marcucci F, Stefanutti G, Gamba P. Use of urokinase in childhood pleural empyema. Pediatr Pulmonol. 2003;35:50-5 pubmed
    Urokinase is an enzyme with a fibrinolytic effect that facilitates pleural empyema drainage through a chest tube...
  28. Waller D, Rengarajan A. Thoracoscopic decortication: a role for video-assisted surgery in chronic postpneumonic pleural empyema. Ann Thorac Surg. 2001;71:1813-6 pubmed
    ..VAT) decortication of the visceral cortex to reexpand entrapped lung in cases of chronic postpneumonic pleural empyema. A prospective cohort study of 48 consecutive patients with multiloculated postpneumonic pleural empyema in ..
  29. Lawrence D, Ohri S, Moxon R, Townsend E, Fountain S. Thoracoscopic debridement of empyema thoracis. Ann Thorac Surg. 1997;64:1448-50 pubmed
    ..1 days (OD) (p = 0.001). Primary surgical therapy with VATD should be considered for all patients with pleural empyema, irrespective of the duration of symptoms...
  30. Schopf L, Fraga J, Amantéa S, Sanches P, Muller A, Borowski S, et al. Induction of pleural empyema in rats by thoracentesis with intrapleural pressure monitoring. Pediatr Surg Int. 2004;20:515-9 pubmed
    ..We conclude that empyema may be induced in rats by the inoculation of Staphylococcus aureus by means of thoracentesis with pleural pressure monitoring. The highest amount of pleural fluid was observed 3 days after bacterial inoculation...
  31. Cassina P, Hauser M, Hillejan L, Greschuchna D, Stamatis G. Video-assisted thoracoscopy in the treatment of pleural empyema: stage-based management and outcome. J Thorac Cardiovasc Surg. 1999;117:234-8 pubmed
    Despite modern diagnostic methods and appropriate treatment, pleural empyema remains a serious problem...
  32. Petrakis I, Kogerakis N, Drositis I, Lasithiotakis K, Bouros D, Chalkiadakis G. Video-assisted thoracoscopic surgery for thoracic empyema: primarily, or after fibrinolytic therapy failure?. Am J Surg. 2004;187:471-4 pubmed
    ..VATS should be considered as the treatment of choice for thoracic empyema, in the fibrinopurulent stage, as it is more effective when applied primarily than when applied after fibrinolytic therapy. ..
  33. Kim B, Oh B, Jang W, Min Y, Park Y, Park J. Video-assisted thoracoscopic decortication for management of postpneumonic pleural empyema. Am J Surg. 2004;188:321-4 pubmed
    ..We present and evaluate our technique and experience with thoracoscopic management of pleural empyema, irrespective of chronicity.
  34. Wolday D, Seyoum B. Pleural empyema due to Salmonella paratyphi in a patient with AIDS. Trop Med Int Health. 1997;2:1140-2 pubmed
    b>Pleural empyema due to Salmonella has rarely been reported in immunocompromised patients...
  35. Eastham K, Freeman R, Kearns A, Eltringham G, Clark J, Leeming J, et al. Clinical features, aetiology and outcome of empyema in children in the north east of England. Thorax. 2004;59:522-5 pubmed
    ..A prospective study was undertaken to investigate the clinical features, aetiology, and outcome of cases of empyema and parapneumonic effusion presenting to a tertiary paediatric respiratory centre between February 1997 and August 2001...
  36. Krzossok S, Benck U, Van Der Woude F, Braun C. [Disseminated intravascular coagulation, perimyocarditis and bilateral pleural empyema in adult Still's disease]. Dtsch Med Wochenschr. 2004;129:2535-7 pubmed
    ..A 21-year-old man was admitted to the hospital because of high fever, arthralgias and myalgias. One week before he was treated with penicillin G orally because of cough and sore throat...
  37. Wait M, Sharma S, Hohn J, Dal Nogare A. A randomized trial of empyema therapy. Chest. 1997;111:1548-51 pubmed
  38. Wiener Kronish J, Sakuma T, Kudoh I, Pittet J, Frank D, Dobbs L, et al. Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits. J Appl Physiol (1985). 1993;75:1661-9 pubmed
    ..aeruginosa (wild-type strain, PAO-1) were required to injure the epithelial barrier and to cause pleural empyema with exudative pleural effusions that contained both the instilled alveolar protein tracer and P. aeruginosa...
  39. Gates R, Hogan M, Weinstein S, Arca M. Drainage, fibrinolytics, or surgery: a comparison of treatment options in pediatric empyema. J Pediatr Surg. 2004;39:1638-42 pubmed
    ..Whereas success has been reported for all of these techniques, VATS has been suggested as the best method because of decreased length of stay...
  40. Ray T, Berkenbosch J, Russo P, Tobias J. Tissue plasminogen activator as an adjuvant therapy for pleural empyema in pediatric patients. J Intensive Care Med. 2004;19:44-50 pubmed
    ..A discussion of other current therapies for empyema, along with a comparison of these therapies to TPA regarding the costs of therapies and risk-benefit ratios, is also included...
  41. Casanova Espinosa A, Cisneros Serrano C, Girón Moreno R, Olivera M, Moreno Balsalobre R, Zamora García E. [Pleural empyema associated with endobronchial lipoma]. Arch Bronconeumol. 2005;41:172-4 pubmed
    ..report the case of an 83-year-old man diagnosed with community-acquired pneumonia that led to complications: pleural empyema caused by Haemophilus influenzae infection and atelectasis of the right middle and lower lobes secondary to a ..
  42. Schultz K, Fan L, Pinsky J, Ochoa L, Smith E, Kaplan S, et al. The changing face of pleural empyemas in children: epidemiology and management. Pediatrics. 2004;113:1735-40 pubmed
    ..This study evaluates the changes that have affected the outcome in children with pleural empyema, including the emergence of resistant organisms, the introduction of the pneumococcal conjugate vaccine, and ..
  43. Baranwal A, Singh M, Marwaha R, Kumar L. Empyema thoracis: a 10-year comparative review of hospitalised children from south Asia. Arch Dis Child. 2003;88:1009-14 pubmed
    ..To study the clinical and microbial profile of childhood empyema in South Asia and to identify the changes over the past three decades...
  44. Cirino L, Gomes F, Batista B. The etiology of extensive pleural effusions with troublesome clinical course among children. Sao Paulo Med J. 2004;122:269-72 pubmed
    ..In São Paulo, pneumonia is the main infectious cause of death among children. Parapneumonic pleural effusion is a possible complication and has to be treated surgically when the patient does not respond to antibiotics...
  45. Guyon G, Allal H, Lalande M, Rodiere M. [Pleural empyema in children: Montpellier's experience]. Arch Pediatr. 2005;12 Suppl 1:S54-7 pubmed
    To assess the management of pleural empyema in pediatric from a medical and surgical experience and a review of the literature.
  46. Ulku R, Onen A, Onat S, Kilinc N, Ozcelik C. Intrapleural fibrinolytic treatment of multiloculated pediatric empyemas. Pediatr Surg Int. 2004;20:520-4 pubmed
    ..IPFA do not seem to be effective in children with chronic phase empyema...
  47. Peltola V, Alanen M, Mertsola J, Ruuskanen O. [Empyema--increasingly common complication connected to pneumonia in children]. Duodecim. 2004;120:1771-7 pubmed
  48. Rzyman W, Skokowski J, Romanowicz G, Lass P, Dziadziuszko R. Decortication in chronic pleural empyema - effect on lung function. Eur J Cardiothorac Surg. 2002;21:502-7 pubmed
    The aim of the present study is to evaluate the lung function before and after the lung decortication in patients with chronic pleural empyema (CPE).
  49. Varela G, Jimenez M, Novoa N, Aranda J. Estimating hospital costs attributable to prolonged air leak in pulmonary lobectomy. Eur J Cardiothorac Surg. 2005;27:329-33 pubmed
    ..The present study aims to compare the prevalence of pulmonary complications (atelectasis, pneumonia and pleural empyema) in patients with or without PAL and to quantify economic costs directly incurred by PAL in a series of ..
  50. Maskell N, Davies C, Nunn A, Hedley E, Gleeson F, Miller R, et al. U.K. Controlled trial of intrapleural streptokinase for pleural infection. N Engl J Med. 2005;352:865-74 pubmed
    ..This use is based on small trials that did not have the statistical power to evaluate accurately important clinical outcomes, including safety. We conducted a trial to clarify the therapeutic role of intrapleural streptokinase...
  51. Martinez Ferro M, Duarte S, Laje P. Single-port thoracoscopy for the treatment of pleural empyema in children. J Pediatr Surg. 2004;39:1194-6 pubmed
    This report is an evaluation of a single-port technique for the thoracoscopic treatment of pleural empyema in children.
  52. Khilnani G. Fibrinolytic therapy for parapneumonic effusion and empyema. Indian J Chest Dis Allied Sci. 2002;44:81-4 pubmed
  53. Waller D. Thoracoscopy in management of postpneumonic pleural infections. Curr Opin Pulm Med. 2002;8:323-6 pubmed
    ..Controversy surrounds its comparative benefits over intrapleural fibrinolysis in early exudative or fibrinopurulent pleural empyema and its usefulness in the treatment of chronic pleural empyema.
  54. Kolditz M, Halank M, Hoffken G. [Parapneumonic effusion and pleural empyema - topical aspects of classification, diagnosis and treatment]. Pneumologie. 2004;58:83-91 pubmed
    ..This overview summarizes the actual aspects of classification, diagnosis and treatment of the parapneumonic effusion and draws conclusions for the daily management of this condition...
  55. Cheng Y, Wu H, Chou S, Kao E. Video-assisted thoracoscopic surgery in the treatment of chronic empyema thoracis. Surg Today. 2002;32:19-25 pubmed
    ..VATD is considered to be a feasible surgical modality for the treatment of stage III empyema thoracis in selected patients...
  56. Colt H. Thoracoscopy. A prospective study of safety and outcome. Chest. 1995;108:324-9 pubmed
    ..To assess a standard classification of adverse events and evaluate the safety and long-term outcome of thoracoscopy in patients with pleural disease...
  57. Weil Olivier C, Levy C, Marguet C, Sardet A, de La Rocque F, Lecuyer A, et al. [Multicenter pediatric retrospective study on pneumonia with empyema in France]. Arch Pediatr. 2005;12:823-6 pubmed
  58. Gulbahar M, Gurturk K. Pyothorax associated with a Mycoplasma sp and Arcanobacterium pyogenes in a kitten. Aust Vet J. 2002;80:344-5 pubmed
    ..The concomitant presence of Mycoplasma sp and A pyogenes could be considered another variation on the polymicrobial nature of pyothorax and associated pleural lesions in cats...
  59. Córdoba López A, Bueno Alvarez Arenas M, Monterrubio Villa J, Corcho Sánchez G. [Streptococcus agalactiae pleural empyema in a healthy adult]. Enferm Infecc Microbiol Clin. 2002;20:478-9 pubmed