onychomycosis

Summary

Summary: A fungal infection of the nail, usually caused by DERMATOPHYTES; YEASTS; or nondermatophyte MOLDS.

Top Publications

  1. Pierard G, Pierard Franchimont C, Quatresooz P. Fungal thigmotropism in onychomycosis and in a clear hydrogel pad model. Dermatology. 2007;215:107-13 pubmed
    ..This behavior has been shown experimentally with fungal hyphae of both dermatophytes and nondermatophyte molds, as well as with the mycelial phase of the dimorphic yeast Candida albicans...
  2. Elewski B, Rich P, Pollak R, Pariser D, Watanabe S, Senda H, et al. Efinaconazole 10% solution in the treatment of toenail onychomycosis: Two phase III multicenter, randomized, double-blind studies. J Am Acad Dermatol. 2013;68:600-608 pubmed publisher
    b>Onychomycosis is a common nail infection, often resulting in nail plate damage and deformity. Topical lacquer treatments have negligible efficacy...
  3. Gupta A, Drummond Main C, Cooper E, Brintnell W, Piraccini B, Tosti A. Systematic review of nondermatophyte mold onychomycosis: diagnosis, clinical types, epidemiology, and treatment. J Am Acad Dermatol. 2012;66:494-502 pubmed publisher
    Nondermatophyte mold (NDM) onychomycosis is difficult to diagnose given that NDMs are common contaminants of the nails and of the mycology laboratory...
  4. Garcia Doval I, Cabo F, Monteagudo B, Alvarez J, Ginarte M, Rodríguez Alvarez M, et al. Clinical diagnosis of toenail onychomycosis is possible in some patients: cross-sectional diagnostic study and development of a diagnostic rule. Br J Dermatol. 2010;163:743-51 pubmed publisher
    Suspected toenail onychomycosis is a frequent problem. Clinical diagnosis has been considered inadequate...
  5. Takahata Y, Hiruma M, Shiraki Y, Tokuhisa Y, Sugita T, Muto M. Treatment of dermatophyte onychomycosis with three pulses of terbinafine (500 mg day for a week). Mycoses. 2009;52:72-6 pubmed publisher
    We assessed the safety and efficacy of pulse therapy with terbinafine tablets in 55 patients with dermatophytic onychomycosis. One pulse consisted of oral terbinafine tablets (500 mg day(-1)) given for 1 week usually followed by a 3-week ..
  6. Shimamura T, Kubota N, Nagasaka S, Suzuki T, Mukai H, Shibuya K. Establishment of a novel model of onychomycosis in rabbits for evaluation of antifungal agents. Antimicrob Agents Chemother. 2011;55:3150-5 pubmed publisher
    We developed a novel model of onychomycosis in which we observed fungi in the deep layer of the nail, and we used the model to evaluate the efficacy of two topical antifungal drugs...
  7. Garg J, Tilak R, Singh S, Gulati A, Garg A, Prakash P, et al. Evaluation of pan-dermatophyte nested PCR in diagnosis of onychomycosis. J Clin Microbiol. 2007;45:3443-5 pubmed
    ..microscopy, culture isolation, and single-round PCR for diagnosis of 152 patients with clinically suspected onychomycosis. Results indicate that nested PCR may be considered the gold standard for the diagnosis of cases of ..
  8. Welsh O, Vera Cabrera L, Welsh E. Onychomycosis. Clin Dermatol. 2010;28:151-9 pubmed publisher
    b>Onychomycosis is a frequent nail disease caused by dermatophytes, yeasts, and nondermatophyte molds. Trichophyton rubrum, T mentagrophytes, and Epidermophyton floccosum are the most common etiologic agents worldwide...
  9. Meireles T, Rocha M, Brilhante R, Cordeiro R, Sidrim J. Successive mycological nail tests for onychomycosis: a strategy to improve diagnosis efficiency. Braz J Infect Dis. 2008;12:333-7 pubmed
    b>Onychomycosis is a fungal infection of nails caused by dermatophytes, yeasts and moulds, accounting for about 50% of onychopathies...

More Information

Publications77

  1. Hay R, Baran R. Onychomycosis: a proposed revision of the clinical classification. J Am Acad Dermatol. 2011;65:1219-27 pubmed publisher
    The classification of onychomycosis, infection of the nail apparatus caused by fungi, has changed over time with the recognition of new pathways of nail infection, new organisms, and new variations in the appearance of diseased infected ..
  2. Nenoff P, Mügge C, Herrmann J, Keller U. Tinea faciei incognito due to Trichophyton rubrum as a result of autoinoculation from onychomycosis. Mycoses. 2007;50 Suppl 2:20-5 pubmed
    ..An infection caused by Trichophyton rubrum of the face always occurs following autoinoculation from a pre-existing tinea pedis and tinea unguium of feet and toenails, sometimes of the fingernails...
  3. Nasir A, Goldstein B, van Cleeff M, Swick L. Clinical evaluation of safety and efficacy of a new topical treatment for onychomycosis. J Drugs Dermatol. 2011;10:1186-91 pubmed
    This clinical study assessed the safety and efficacy of an investigational topical product for the treatment of onychomycosis (nail fungus)...
  4. Dai T, Tegos G, Rolz Cruz G, Cumbie W, Hamblin M. Ultraviolet C inactivation of dermatophytes: implications for treatment of onychomycosis. Br J Dermatol. 2008;158:1239-46 pubmed publisher
    b>Onychomycosis responds to systemic antifungals and sometimes to topical lacquers, but alternative treatments are desirable...
  5. Gupta A, Uro M, Cooper E. Onychomycosis therapy: past, present, future. J Drugs Dermatol. 2010;9:1109-13 pubmed
    Methods to treat onychomycosis are varied, using therapies that can be categorized as topical, oral or device-related. Since their development, oral therapies have represented the gold standard for treatment over other methods...
  6. Piraccini B, Sisti A, Tosti A. Long-term follow-up of toenail onychomycosis caused by dermatophytes after successful treatment with systemic antifungal agents. J Am Acad Dermatol. 2010;62:411-4 pubmed publisher
    Recurrences (relapse or reinfection) of onychomycosis are not uncommon, with percentages reported in various studies ranging from 10% to 53%...
  7. Souza P, Vettorato G, Pinto G, Duquia R, Amaro T, Almeira Junior H, et al. Concordance between direct microscopy and fungical culture for the diagnostic of feet's onychomycosis. An Bras Dermatol. 2012;87:157-9 pubmed
    ..microscopy and fungical culture from subungueal samples of the patients with clinical suspicion of feet's onychomycosis. The agreement occurred in 56.1% of the exams with dermatophytes, in 52.4% by others fungi and in 90...
  8. Rothmund G, Sattler E, Kaestle R, Fischer C, Haas C, Starz H, et al. Confocal laser scanning microscopy as a new valuable tool in the diagnosis of onychomycosis - comparison of six diagnostic methods. Mycoses. 2013;56:47-55 pubmed publisher
    b>Onychomycosis is common and can mimic several different nail disorders. Accurate diagnosis is essential to choose the optimum antifungal therapy...
  9. Tanrıverdi S, Ozer O. Novel topical formulations of Terbinafine-HCl for treatment of onychomycosis. Eur J Pharm Sci. 2013;48:628-36 pubmed publisher
    Terbinafine hydrochloride (TBF-HCl) is an active substance that is using for treatment of onychomycosis. Onychomycosis is a fungal infection which is the most common disease of nail plate...
  10. Sigurgeirsson B. Prognostic factors for cure following treatment of onychomycosis. J Eur Acad Dermatol Venereol. 2010;24:679-84 pubmed publisher
    To examine if host baseline factors and week 24 mycology results are associated with mycological and clinical cure in patients with onychomycosis treated with oral terbinafine.
  11. Moreno G, Arenas R. Other fungi causing onychomycosis. Clin Dermatol. 2010;28:160-3 pubmed publisher
    Nondermatophyte onychomycosis account for 2% to 12% of all nail fungal infections and can be caused by a wide range of fungi, mainly Scopulariopsis brevicaulis, Aspergillus versicolor, A. flavus, A. niger, A...
  12. Watanabe S, Harada T, Hiruma M, Iozumi K, Katoh T, Mochizuki T, et al. Epidemiological survey of foot diseases in Japan: results of 30,000 foot checks by dermatologists. J Dermatol. 2010;37:397-406 pubmed publisher
    ..2% used topical medication only. This survey showed that often patients are not aware of fungal infections and that their treatment is sometimes insufficient. Dermatologists should actively examine and treat patients with TP and TU...
  13. Shemer A, Davidovici B, Grunwald M, Trau H, Amichai B. New criteria for the laboratory diagnosis of nondermatophyte moulds in onychomycosis. Br J Dermatol. 2009;160:37-9 pubmed publisher
    Nondermatophyte moulds (NDM) may be found as aetiological agents or as contaminants in onychomycosis. The classic and most used criteria for the diagnosis of NDM are those established by English in 1976.
  14. Shemer A, Trau H, Davidovici B, Amichai B, Grunwald M. Onychomycosis: rationalization of topical treatment. Isr Med Assoc J. 2008;10:415-6 pubmed
    ..Fungal infection of the nail affects millions of people worldwide and has an estimated prevalence of more than 10% of the general population...
  15. Dias N, Santos C, Portela M, Lima N. Toenail onychomycosis in a Portuguese geriatric population. Mycopathologia. 2011;172:55-61 pubmed publisher
    b>Onychomycosis is a common fungal infection of the nail but few data of mycological features in geriatric Portuguese population are yet available...
  16. Ghannoum M, Isham N, Herbert J, Henry W, Yurdakul S. Activity of TDT 067 (terbinafine in Transfersome) against agents of onychomycosis, as determined by minimum inhibitory and fungicidal concentrations. J Clin Microbiol. 2011;49:1716-20 pubmed publisher
    ..mg/ml of terbinafine in Transfersome that has been developed to deliver terbinafine to the nail bed to treat onychomycosis. In this study, we report the in vitro activities of TDT 067 against dermatophytes, compared with those of the ..
  17. Ozkan F, Ozturk P, Ozyurt K, Incı M, Kalender A, Bakan B, et al. Frequency of peripheral arterial disease and venous insufficiency in toenail onychomycosis. J Dermatol. 2013;40:107-10 pubmed publisher
    b>Onychomycosis in toenails is a common fungal infection and vascular abnormalities of lower extremities have been thought as one of the predisposing conditions...
  18. Aghamirian M, Ghiasian S. Onychomycosis in Iran: epidemiology, causative agents and clinical features. Nihon Ishinkin Gakkai Zasshi. 2010;51:23-9 pubmed
    b>Onychomycosis represents the most frequently encountered nail disease, which is difficult to eradicate with drug treatment.
  19. Cursi I, Freitas L, Neves M, Silva I. Onycomychosis due to Scytalidium spp.: a clinical and epidemiologic study at a University Hospital in Rio de Janeiro, Brazil. An Bras Dermatol. 2011;86:689-93 pubmed
    ..It is currently considered a primary pathogen of the nail. The prevalence of nail infections caused by this fungus has been increasing in recent decades, although few published studies have been done on its epidemiology...
  20. Yin Z, Xu J, Luo D. A meta-analysis comparing long-term recurrences of toenail onychomycosis after successful treatment with terbinafine versus itraconazole. J Dermatolog Treat. 2012;23:449-52 pubmed publisher
    As the most frequently used systemic antifungal agents for onychomycosis, terbinafine and itraconazole have both proved to have the conditions of recurrence in various degrees during follow-up period after end of therapy; very little is ..
  21. Shemer A, Nathansohn N, Kaplan B, Trau H. Toenail abnormalities and onychomycosis in chronic venous insufficiency of the legs: should we treat?. J Eur Acad Dermatol Venereol. 2008;22:279-82 pubmed publisher
    Toenail manifestations of chronic venous insufficiency (CVI) may often mimic the nail changes of onychomycosis. The current study aims to determine the frequency of toenails deformations in patients with CVI, onychomycosis prevalence ..
  22. Kaur R, Kashyap B, Bhalla P. Onychomycosis--epidemiology, diagnosis and management. Indian J Med Microbiol. 2008;26:108-16 pubmed
    b>Onychomycosis is a fungal infection of nails caused by dermatophytes, yeasts or nondermatophyte molds and represents about 30% of mycotic cutaneous infections...
  23. Gupta A, Cooper E. Update in antifungal therapy of dermatophytosis. Mycopathologia. 2008;166:353-67 pubmed publisher
    ..For tinea unguium (onychomycosis) and tinea capitis, oral therapies are the primary treatments provided...
  24. Mayser P, Freund V, Budihardja D. Toenail onychomycosis in diabetic patients: issues and management. Am J Clin Dermatol. 2009;10:211-20 pubmed publisher
    ..A recent large prospective study has shown that onychomycosis is among the most significant predictors of foot ulcer...
  25. Pelegrini A, Takahashi J, Pereira C, Pessoni R, Souza M. Incidence of dermatophytosis in a public hospital of São Bernardo do Campo, São Paulo State, Brazil. Rev Iberoam Micol. 2009;26:118-20 pubmed publisher
    ..6% of the infections. These data agree with findings reported in the literature indicating a lower prevalence of filamentous fungi, such as Epidermophyton, Trichophyton, and Microsporum, in dermatomycosis...
  26. Chang C, Young Xu Y, Kurth T, Orav J, Chan A. The safety of oral antifungal treatments for superficial dermatophytosis and onychomycosis: a meta-analysis. Am J Med. 2007;120:791-8 pubmed
    We estimated the absolute risks of treatment termination and incidence of adverse liver outcomes among all commonly used oral antifungal treatments for superficial dermatophytosis and onychomycosis.
  27. Sipponen P, Sipponen A, Lohi J, Soini M, Tapanainen R, Jokinen J. Natural coniferous resin lacquer in treatment of toenail onychomycosis: an observational study. Mycoses. 2013;56:289-96 pubmed publisher
    ..study, we tested the clinical effectiveness of a lacquer composed of spruce resin for topical treatment of onychomycosis. Thirty-seven patients with clinical diagnosis of onychomycosis were enrolled into the study...
  28. Carney C, Tosti A, Daniel R, Scher R, Rich P, DeCoster J, et al. A new classification system for grading the severity of onychomycosis: Onychomycosis Severity Index. Arch Dermatol. 2011;147:1277-82 pubmed publisher
    To establish and validate a new system to define the severity of onychomycosis. The Onychomycosis Severity Index (OSI) score is obtained by multiplying the score for the area of involvement (range, 0-5) by the score for the proximity of ..
  29. Singal A, Khanna D. Onychomycosis: Diagnosis and management. Indian J Dermatol Venereol Leprol. 2011;77:659-72 pubmed publisher
    b>Onychomycosis is a common nail ailment associated with significant physical and psychological morbidity...
  30. Zhao Y, Li L, Wang J, Kang K, Zhang Q. Cutaneous malasseziasis: four case reports of atypical dermatitis and onychomycosis caused by Malassezia. Int J Dermatol. 2010;49:141-5 pubmed publisher
    ..This study investigates four special cases associated with Malassezia...
  31. Malay D, Yi S, Borowsky P, Downey M, Mlodzienski A. Efficacy of debridement alone versus debridement combined with topical antifungal nail lacquer for the treatment of pedal onychomycosis: a randomized, controlled trial. J Foot Ankle Surg. 2009;48:294-308 pubmed publisher
    Pedal onychomycosis is a common malady caused by dermatophytes, saprophytes, and yeasts...
  32. Brown S. Efficacy of fluconazole for the treatment of onychomycosis. Ann Pharmacother. 2009;43:1684-91 pubmed publisher
    To evaluate the efficacy of fluconazole for the treatment of onychomycosis.
  33. Piraccini B, Gianni C. Update on the management of onychomycosis. G Ital Dermatol Venereol. 2013;148:633-8 pubmed
    b>Onychomycosis is a fungal infection of the nail which is highly prevalent in the general population, particularly among older individuals. Patients seek care because the disease is infectious or simply for an esthetic discomfort...
  34. Bontems O, Hauser P, Monod M. Evaluation of a polymerase chain reaction-restriction fragment length polymorphism assay for dermatophyte and nondermatophyte identification in onychomycosis. Br J Dermatol. 2009;161:791-6 pubmed publisher
    ..The correct identification of the aetiological agent of nail infections is necessary in order to recommend appropriate treatment...
  35. Landsman A, Robbins A, Angelini P, Wu C, Cook J, Oster M, et al. Treatment of mild, moderate, and severe onychomycosis using 870- and 930-nm light exposure. J Am Podiatr Med Assoc. 2010;100:166-77 pubmed
    The Noveon is a unique dual-wavelength near-infrared diode laser used to treat onychomycosis. The device operates at physiologic temperatures that are thermally safe for human tissue...
  36. Tuccori M, Bresci F, Guidi B, Blandizzi C, Del Tacca M, Di Paolo M. Fatal hepatitis after long-term pulse itraconazole treatment for onychomycosis. Ann Pharmacother. 2008;42:1112-7 pubmed publisher
    ..To report the occurrence of acute cytolytic hepatitis in a patient exposed to pulse itraconazole therapy for 24 weeks and provide a concise review of the literature on cases of itraconazole-induced hepatitis...
  37. Sigurgeirsson B, Olafsson J, Steinsson J, Kerrouche N, Sidou F. Efficacy of amorolfine nail lacquer for the prophylaxis of onychomycosis over 3 years. J Eur Acad Dermatol Venereol. 2010;24:910-5 pubmed publisher
    Standard treatment for onychomycosis often results in less than half of subjects achieving disease-free nails. Onychomycosis is even more challenging to treat as relapses and re-infections are common.
  38. Kumar S, Kimball A. New antifungal therapies for the treatment of onychomycosis. Expert Opin Investig Drugs. 2009;18:727-34 pubmed
    b>Onychomycosis is a common disorder of nails caused by diverse spectrum of fungi ranging from dermatophytes to nondermatophyte molds and yeasts...
  39. Hashemi S, Gerami M, Zibafar E, Daei M, Moazeni M, Nasrollahi A. Onychomycosis in Tehran: mycological study of 504 patients. Mycoses. 2010;53:251-5 pubmed publisher
    b>Onychomycosis is a common nail disorder resulting from the invasion of the nail plate by a dermatophyte, yeast or mould species and gives rise to some diverse clinical presentations...
  40. Chadeganipour M, Nilipour S, Ahmadi G. Study of onychomycosis in Isfahan, Iran. Mycoses. 2010;53:153-7 pubmed publisher
    A mycological study was undertaken in 488 patients suspected of onychomycosis in Isfahan, a large province of Iran, to gain more insight into the prevalence and aetiology of this infection...
  41. Martins E, Guerrer L, Cunha K, Soares M, de Almeida M. [Onychomycosis: clinical, epidemiological and mycological study in the municipality of São José do Rio Preto]. Rev Soc Bras Med Trop. 2007;40:596-8 pubmed
    ..Candida parapsilosis (47%) and Trichophyton rubrum (38%) were prevalent. They were 100% sensitive to ketoconazole and 99% sensitive to amphotericin B. The highest prevalences were among women (80%), adults (62%) and toes (84%)...
  42. Amichai B, Davidovici B, Trau H, Lyakhovitsky A, Grunwald M, Shemer A. A rationale for systemic treatment in onychomycosis with negative results on fungal examination. Clin Exp Dermatol. 2011;36:724-7 pubmed publisher
    ..Laboratory confirmation of fungal infection is currently accepted as a requirement before initiation of antifungal treatment in clinical practice...
  43. Gaburri D, Chebli J, Zanine A, Gamonal A, Gaburri P. Onychomycosis in inflammatory bowel diseases. J Eur Acad Dermatol Venereol. 2008;22:807-12 pubmed publisher
    As far as we have sought for in Medline and PubMed, not one study until now has evaluated the prevalence of onychomycosis in patients with inflammatory bowel disease (IBD)...
  44. Namitome K, Kano R, Sekiguchi M, Iwasaki T, Kaneshima T, Nishifuji K. Isolation of Fusarium sp. from a claw of a dog with onychomycosis. J Vet Med Sci. 2011;73:965-9 pubmed
    ..To the authors' knowledge, this is the first case report of canine onychomycosis in which Fusarium sp. was isolated from the affected claw.
  45. Surjushe A, Kamath R, Oberai C, Saple D, Thakre M, Dharmshale S, et al. A clinical and mycological study of onychomycosis in HIV infection. Indian J Dermatol Venereol Leprol. 2007;73:397-401 pubmed
    b>Onychomycosis is one of the early manifestations of HIV infection with a prevalence of 15-40%...
  46. Gupta A, Simpson F. New therapeutic options for onychomycosis. Expert Opin Pharmacother. 2012;13:1131-42 pubmed publisher
    b>Onychomycosis is a fungal infection of the nail apparatus that affects 10 - 30% of the global population...
  47. Silva J, Doimo G, Faria D. The use of high frequency waves to treat onychomycosis: preliminary communication of three cases. An Bras Dermatol. 2011;86:598-600 pubmed
    The research evaluated the efficacy of high frequency waves in the treatment of onychomycosis in three patients during twelve months through the clinical examination of nails and also through mycological examination...
  48. Derby R, Rohal P, Jackson C, Beutler A, Olsen C. Novel treatment of onychomycosis using over-the-counter mentholated ointment: a clinical case series. J Am Board Fam Med. 2011;24:69-74 pubmed publisher
    current medication treatments for onychomycosis have less than full cure-rate efficacy and have the potential for adverse side effects...
  49. Romero Cerecero O, Zamilpa A, Jiménez Ferrer J, Rojas Bribiesca G, Roman Ramos R, Tortoriello J. Double-blind clinical trial for evaluating the effectiveness and tolerability of Ageratina pichinchensis extract on patients with mild to moderate onychomycosis. A comparative study with ciclopirox. Planta Med. 2008;74:1430-5 pubmed publisher
    ..b>Onychomycosis, also known as tinea of the nails or tinea unguium, constitutes an infection of the nails produced by ..
  50. Shemer A, Nathansohn N, Trau H, Amichai B, Grunwald M. Ciclopirox nail lacquer for the treatment of onychomycosis: an open non-comparative study. J Dermatol. 2010;37:137-9 pubmed publisher
    b>Onychomycosis is a relatively common disease accounting for up to 50% of all nail disorders. Topical treatment, although less effective than systemic, is usually preferred by patients...
  51. Hubka V, Mencl K, Skorepová M, Lyskova P, Zálabská E. Phaeohyphomycosis and onychomycosis due to Chaetomium spp., including the first report of Chaetomium brasiliense infection. Med Mycol. 2011;49:724-33 pubmed publisher
    ..The second case involved onychomycosis with strikingly brown nail discoloration due to Chaetomium globosum in an otherwise healthy patient...
  52. Baudraz Rosselet F, Ruffieux C, Lurati M, Bontems O, Monod M. Onychomycosis insensitive to systemic terbinafine and azole treatments reveals non-dermatophyte moulds as infectious agents. Dermatology. 2010;220:164-8 pubmed publisher
    ..Dermatophytes are the main cause of onychomycoses, but various non-dermatophyte filamentous fungi are often isolated from abnormal nails...
  53. Xavier A, Oliveira J, Ribeiro V, Souza M. Epidemiological aspects of patients with ungual and cutaneous lesions caused by Scytalidium spp. An Bras Dermatol. 2010;85:805-10 pubmed
    Dermatomycoses caused by non-dermatophyte filamentous fungi are rare infections, except for onychomycosis, whose prevalence has increased over the past few years. Among these etiologic agents, we highlight Scytalidium dimidiatum and S...
  54. Ebihara M, Makimura K, Sato K, Abe S, Tsuboi R. Molecular detection of dermatophytes and nondermatophytes in onychomycosis by nested polymerase chain reaction based on 28S ribosomal RNA gene sequences. Br J Dermatol. 2009;161:1038-44 pubmed publisher
    b>Onychomycosis is often caused by dermatophytes, but the role of nondermatophytes is underestimated due to the difficulty of identifying them by conventional direct microscopy and culture.
  55. Takahata Y, Hiruma M, Sugita T, Muto M. A case of onychomycosis due to Aspergillus sydowii diagnosed using DNA sequence analysis. Mycoses. 2008;51:170-3 pubmed publisher
    We report a case of disto-lateral subungal onychomycosis of the first toe of the right foot of a 33-year-old female...
  56. Leibovici V, Hershko K, Ingber A, Westerman M, Leviatan Strauss N, Hochberg M. Increased prevalence of onychomycosis among psoriatic patients in Israel. Acta Derm Venereol. 2008;88:31-3 pubmed publisher
    Published data on the prevalence of onychomycosis in psoriasis patients compared with healthy controls are controversial, We therefore conducted a prospective study of toenail onychomycosis, among 113 psoriatic and 106 healthy non-..
  57. Westerberg D, Voyack M. Onychomycosis: Current trends in diagnosis and treatment. Am Fam Physician. 2013;88:762-70 pubmed
    b>Onychomycosis is a fungal infection of the nails that causes discoloration, thickening, and separation from the nail bed...
  58. Sun P, Ju Y. Onychomycosis caused by Phaeoacremonium parasiticum: first case report. Mycoses. 2011;54:172-4 pubmed publisher
    A variety of non-dermatophyte moulds can cause human onychomycosis. We report an unusual case of onychomycosis caused by Phaeoacremonium parasiticum, which has not been mentioned in the literature before...
  59. Jaiswal A, Sharma R, Garg A. An open randomized comparative study to test the efficacy and safety of oral terbinafine pulse as a monotherapy and in combination with topical ciclopirox olamine 8% or topical amorolfine hydrochloride 5% in the treatment of onychomycosis. Indian J Dermatol Venereol Leprol. 2007;73:393-6 pubmed
    b>Onychomycosis is a fungal infection of nails caused by dermatophytes, yeasts and molds.
  60. Guilhermetti E, Takahachi G, Shinobu C, Svidzinski T. Fusarium spp. as agents of onychomycosis in immunocompetent hosts. Int J Dermatol. 2007;46:822-6 pubmed
  61. Farwa U, Abbasi S, Mirza I, Amjad A, Ikram A, Ikram A, et al. Non-dermatophyte moulds as pathogens of onychomycosis. J Coll Physicians Surg Pak. 2011;21:597-600 pubmed publisher
    To determine the role and pattern of non-dermatophyte moulds as causative agents of onychomycosis.
  62. Manevitch Z, Lev D, Hochberg M, Palhan M, Lewis A, Enk C. Direct antifungal effect of femtosecond laser on Trichophyton rubrum onychomycosis. Photochem Photobiol. 2010;86:476-9 pubmed publisher
    b>Onychomycosis is caused by dermatophyte infection of the nail...
  63. Thomas J, Jacobson G, Narkowicz C, Peterson G, Burnet H, Sharpe C. Toenail onychomycosis: an important global disease burden. J Clin Pharm Ther. 2010;35:497-519 pubmed publisher
    b>Onychomycosis is a fungal infection of the nail plate or nail bed. It does not usually cure itself and it can trigger more infectious lesions in other parts of the body...
  64. Menendez S, Falcón L, Maqueira Y. Therapeutic efficacy of topical OLEOZON® in patients suffering from onychomycosis. Mycoses. 2011;54:e272-7 pubmed publisher
    The results of the use of ozonised sunflower oil (OLEOZON(®)) in the treatment of onychomycosis, based on its known antimycotic action and good skin tolerance, by means of a controlled randomised phase III assay are presented...
  65. Lurati M, Baudraz Rosselet F, Vernez M, Spring P, Bontems O, Fratti M, et al. Efficacious treatment of non-dermatophyte mould onychomycosis with topical amphotericin B. Dermatology. 2011;223:289-92 pubmed publisher
    Dermatophytes are the main cause of onychomycosis, but various non-dermatophyte moulds (NDMs) are often the infectious agents in abnormal nails. In particular, Fusarium spp...
  66. de Giorgi V, Sestini S, Massi D, Panelos J, Papi F, Dini M, et al. Subungual melanoma: a particularly invasive "onychomycosis". J Am Geriatr Soc. 2007;55:2094-6 pubmed
  67. Van Duyn Graham L, Elewski B. Recent updates in oral terbinafine: its use in onychomycosis and tinea capitis in the US. Mycoses. 2011;54:e679-85 pubmed publisher
    b>Onychomycosis and tinea capitis are prevalent fungal diseases that are difficult to cure and usually require systemic treatment. Onychomycosis has high recurrence rates and can significantly affect a patient's quality of life...
  68. Allevato M. Diseases mimicking onychomycosis. Clin Dermatol. 2010;28:164-77 pubmed publisher
    ..One of the first differential diagnoses that should be considered when an onychodystrophic nail is observed is onychomycosis, which is the cause in 50% of cases.