infection

Summary

Summary: Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.

Top Publications

  1. Paudel S, Alispahic M, Liebhart D, Hess M, Hess C. Assessing pathogenicity of Gallibacterium anatis in a natural infection model: the respiratory and reproductive tracts of chickens are targets for bacterial colonization. Avian Pathol. 2013;42:527-35 pubmed publisher
    Two separate bird trials were performed to establish a reliable route of infection for Gallibacterium anatis in chickens, comparing intranasal (i.n.) and intravenous (i.v.) applications...
  2. Olsen C. Statistics in Infection and immunity revisited. Infect Immun. 2014;82:916-20 pubmed publisher
    In 2003, a review of the use of statistics in Infection and Immunity (IAI) found that more than half of articles had errors of statistical analysis or reporting of statistical results...
  3. Carey A, Tan C, Mirza S, Irving Rodgers H, Webb R, Lam A, et al. Infection and cellular defense dynamics in a novel 17?-estradiol murine model of chronic human group B streptococcus genital tract colonization reveal a role for hemolysin in persistence and neutrophil accumulation. J Immunol. 2014;192:1718-31 pubmed publisher
    ..Overall, this study defines key infection dynamics in a novel murine model of chronic GBS genital tract colonization and establishes previously unknown ..
  4. Rinaldi S, Catalano R, Wade J, Rossi A, Norman J. Decidual neutrophil infiltration is not required for preterm birth in a mouse model of infection-induced preterm labor. J Immunol. 2014;192:2315-25 pubmed publisher
    ..Neutrophil infiltration of the uteroplacental tissues has been particularly associated with infection-associated preterm labor (PTL) in both women and mouse models...
  5. Churlaud G, Jimenez V, Ruberte J, Amadoudji Zin M, Fourcade G, Gottrand G, et al. Sustained stimulation and expansion of Tregs by IL2 control autoimmunity without impairing immune responses to infection, vaccination and cancer. Clin Immunol. 2014;151:114-26 pubmed publisher
    ..They showed no change in the occurrence and growth of chemically-induced tumors. Altogether, chronic low-dose IL2 treatment does not affect beneficial effector immune responses at doses that prevent autoimmune diabetes. ..
  6. Glatman Zaretsky A, Engiles J, Hunter C. Infection-induced changes in hematopoiesis. J Immunol. 2014;192:27-33 pubmed publisher
  7. Way E, Chen K, Kolls J. Dysregulation in lung immunity - the protective and pathologic Th17 response in infection. Eur J Immunol. 2013;43:3116-24 pubmed publisher
    ..In this Mini-Review we highlight recent advances in the protective and pathologic roles of Th17 cytokines in the context of infection at the pulmonary barrier.
  8. Ebenhan T, Zeevaart J, Venter J, Govender T, Kruger G, Jarvis N, et al. Preclinical evaluation of 68Ga-labeled 1,4,7-triazacyclononane-1,4,7-triacetic acid-ubiquicidin as a radioligand for PET infection imaging. J Nucl Med. 2014;55:308-14 pubmed publisher
    ..99m)Tc-UBI29-41 was previously tested for detecting infection in humans using SPECT...
  9. Hills N, Johnston S, Sidney S, Zielinski B, Fullerton H. Recent trauma and acute infection as risk factors for childhood arterial ischemic stroke. Ann Neurol. 2012;72:850-8 pubmed publisher
    Trauma and acute infection have been associated with stroke in adults, and are prevalent exposures in children. We hypothesized that these environmental factors are independently associated with childhood arterial ischemic stroke (AIS)...

More Information

Publications106 found, 100 shown here

  1. Lawrence B, Vorderstrasse B. New insights into the aryl hydrocarbon receptor as a modulator of host responses to infection. Semin Immunopathol. 2013;35:615-26 pubmed publisher
    The host response to infection is known to be influenced by many factors, including genetics, nutritional status, age, as well as drug and chemical exposures...
  2. Roquer J, Cuadrado Godia E, Giralt Steinthauer E, Jimena S, Jimenez Conde J, Martinez Rodriguez J, et al. Previous infection and stroke: a prospective study. Cerebrovasc Dis. 2012;33:310-5 pubmed publisher
    ..We sought to describe, in a large prospective series, the frequency of previous infection (PI) in IS and intracerebral hemorrhage (ICH), and to assess whether any relationship with stroke subtype or ..
  3. Hotz C, Chileshe J, Siamusantu W, Palaniappan U, Kafwembe E. Vitamin A intake and infection are associated with plasma retinol among pre-school children in rural Zambia. Public Health Nutr. 2012;15:1688-96 pubmed publisher
    To determine the prevalence of vitamin A deficiency, infection and adequacy of vitamin A intakes among Zambian children, and the contribution of dietary vitamin A and infection to vitamin A status...
  4. Blander J, Torchinsky M, Campisi L. Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells. Immunol Res. 2012;54:50-68 pubmed publisher
    ..Notorious among these has been microbial infection. Older studies describing associations between microbial infection and autoimmune disease are now followed by ..
  5. Zheng J, Liu Y, Lau Y, Tu W. ??-T cells: an unpolished sword in human anti-infection immunity. Cell Mol Immunol. 2013;10:50-7 pubmed publisher
    ..T cells have both 'innate' and 'adaptive' characteristics in the immune response, and their anti-infection activities are mediated by multiple pathways that are under elaborate regulation by other immune components...
  6. Lin L, Chen Y, Chang Y, Lee C. Neuroendocrine responses of a crustacean host to viral infection: effects of infection of white spot syndrome virus on the expression and release of crustacean hyperglycemic hormone in the crayfish Procambarus clarkii. Comp Biochem Physiol A Mol Integr Physiol. 2013;164:327-32 pubmed publisher
    ..characterize the changes in crustacean hyperglycemic hormone (CHH) transcript and peptide levels in response to infection of white spot syndrome virus (WSSV) in a crustacean, Procambarus clarkii...
  7. Kostkova P, Fowler D, Wiseman S, Weinberg J. Major infection events over 5 years: how is media coverage influencing online information needs of health care professionals and the public?. J Med Internet Res. 2013;15:e107 pubmed publisher
    ..To investigate professional and public online information needs around major infection outbreaks and correlate these with media coverage...
  8. Shaw P, Feske S. Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity. J Physiol. 2012;590:4157-67 pubmed publisher
    ..This review provides a concise discussion of the role of CRAC channels in these lymphocyte populations and the regulation of adaptive immune responses to infection, in autoimmunity and inflammation.
  9. Morris D, Khurasany M, Nguyen T, Kim J, Guilford F, Mehta R, et al. Glutathione and infection. Biochim Biophys Acta. 2013;1830:3329-49 pubmed publisher
    ..against the detrimental effects of oxidative stress within the human body, as well as protection against infection by exogenous microbial organisms...
  10. Oikonomopoulou K, Brinc D, Kyriacou K, Diamandis E. Infection and cancer: revaluation of the hygiene hypothesis. Clin Cancer Res. 2013;19:2834-41 pubmed publisher
    ..The factors that direct this dichotomous influence of infection-mediated immunity on carcinogenesis are not well understood...
  11. Rowles D, Terhune S, Cristea I. Discovery of host-viral protein complexes during infection. Methods Mol Biol. 2013;1064:43-70 pubmed publisher
    ..The rapid identification of host proteins targeted by viral proteins during infection provides significant insights into mechanisms of viral protein function...
  12. Yasmin S, Mukherjee A. A cyto-epidemiological study on married women in reproductive age group (15-49 years) regarding reproductive tract infection in a rural community of West Bengal. Indian J Public Health. 2012;56:204-9 pubmed publisher
    Reproductive tract infection (RTI) represents a major public health problem in India...
  13. Ansuini V, Rigante D, Esposito S. Debate around infection-dependent hemophagocytic syndrome in paediatrics. BMC Infect Dis. 2013;13:15 pubmed publisher
    ..b>Infection-dependent HPS has been widely observed, but there are no data concerning its incidence in children...
  14. Wukich D, Hobizal K, Brooks M. Severity of diabetic foot infection and rate of limb salvage. Foot Ankle Int. 2013;34:351-8 pubmed publisher
    ..in patients with diabetes mellitus (DM), and proper classification of the severity of diabetic foot infection (DFI) is important in determining an effective antibiotic regimen, the need for hospitalization and surgery, and ..
  15. Archibald L, Jarvis W. Health care-associated infection outbreak investigations by the Centers for Disease Control and Prevention, 1946-2005. Am J Epidemiol. 2011;174:S47-64 pubmed publisher
    ..Data from investigations invariably contributed to CDC-generated guidelines for prevention and control of health care-associated infections. ..
  16. Milner J, Beck M. The impact of obesity on the immune response to infection. Proc Nutr Soc. 2012;71:298-306 pubmed publisher
    ..This is a review of research findings concerning the impact of obesity on the immune response to infection, including a discussion of possible mechanisms...
  17. Madan J, Farzan S, Hibberd P, Karagas M. Normal neonatal microbiome variation in relation to environmental factors, infection and allergy. Curr Opin Pediatr. 2012;24:753-9 pubmed publisher
    ..the impact of multiple exposures, and its effects on immune response and clinical outcomes such as allergy and infection. Postnatal exposures play a central role in the complex interactions between the nearly blank canvas of the ..
  18. Farzan S, Korrick S, Li Z, Enelow R, Gandolfi A, Madan J, et al. In utero arsenic exposure and infant infection in a United States cohort: a prospective study. Environ Res. 2013;126:24-30 pubmed publisher
    ..As), a ubiquitous environmental toxicant, has recently been linked to disrupted immune function and enhanced infection susceptibility in highly exposed populations...
  19. Dixon W, Abrahamowicz M, Beauchamp M, Ray D, Bernatsky S, Suissa S, et al. Immediate and delayed impact of oral glucocorticoid therapy on risk of serious infection in older patients with rheumatoid arthritis: a nested case-control analysis. Ann Rheum Dis. 2012;71:1128-33 pubmed publisher
    To explore the relationship of serious infection risk with current and prior oral glucocorticoid (GC) therapy in elderly patients with rheumatoid arthritis (RA)...
  20. Palestro C, Love C. Decreased sensitivity of (18)F-fluorodeoxyglucose imaging in infection and inflammation. Semin Nucl Med. 2012;42:261-6 pubmed publisher
    Nuclear medicine plays an important role in the evaluation of inflammation and infection. Although (99m)Tc-methylene diphosphonate, (67)Ga-citrate, and in vitro labeled autologous leukocyte imaging are useful procedures, there are ..
  21. Cypowyj S, Picard C, Marodi L, Casanova J, Puel A. Immunity to infection in IL-17-deficient mice and humans. Eur J Immunol. 2012;42:2246-54 pubmed publisher
  22. Abdelrahman H, Siam A, Shawky A, Ezzati A, Boehm H. Infection after vertebroplasty or kyphoplasty. A series of nine cases and review of literature. Spine J. 2013;13:1809-17 pubmed publisher
    ..b>Infection after vertebroplasty or kyphoplasty is a serious, yet, rarely reported complication...
  23. Herbinger K, Schunk M, Nothdurft H, von Sonnenburg F, Loscher T, Bretzel G. Comparative study on infection-induced thrombocytopenia among returned travellers. Infection. 2012;40:373-9 pubmed publisher
    ..was significantly more frequent among patients with malaria (63%), acute human immunodeficiency virus infection (48%), dengue fever/dengue haemorrhagic fever (DF/DHF; 47%), Epstein-Barr virus infectious mononucleosis (23%), ..
  24. Rodelo J, De La Rosa G, Valencia M, Ospina S, Arango C, Gomez C, et al. D-dimer is a significant prognostic factor in patients with suspected infection and sepsis. Am J Emerg Med. 2012;30:1991-9 pubmed publisher
    ..and d-dimer (DD) are markers of mortality in patients admitted to the emergency department (ED) with suspected infection and sepsis. We conducted a prospective cohort in a university hospital in Medellín, Colombia...
  25. Jian J, Konopka J, Liu C. Insights into the role of progranulin in immunity, infection, and inflammation. J Leukoc Biol. 2013;93:199-208 pubmed publisher
    ..the data supporting an emerging role of PGRN in the fields of the "Cubic of I", namely, immunity, infection, and inflammation, with special focus on its regulation of autoimmune syndromes...
  26. Jin R, Zhu X, Liu L, Nanda A, Granger D, Li G. Simvastatin attenuates stroke-induced splenic atrophy and lung susceptibility to spontaneous bacterial infection in mice. Stroke. 2013;44:1135-43 pubmed publisher
    ..the effects of simvastatin treatment on stroke-induced splenic atrophy and lung susceptibility to bacterial infection in acute experimental stroke in mice...
  27. Levi M, van der Poll T, Schultz M. New insights into pathways that determine the link between infection and thrombosis. Neth J Med. 2012;70:114-20 pubmed
    Severe infection is often linked to prothrombotic events...
  28. Neyt K, Perros F, GeurtsvanKessel C, Hammad H, Lambrecht B. Tertiary lymphoid organs in infection and autoimmunity. Trends Immunol. 2012;33:297-305 pubmed publisher
    ..Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation...
  29. Hainer V, Hainerová I, Zamrazilová H. [Role of infection in the pathogenesis of obesity]. Cas Lek Cesk. 2012;151:563-7 pubmed
    ..However, additional pathogenetic factors should be considered, including an infection. Several viruses causing obesity have been described in mice, chicken, rats, hamsters and monkeys...
  30. Kreisman L, Cobb B. Infection, inflammation and host carbohydrates: a Glyco-Evasion Hypothesis. Glycobiology. 2012;22:1019-30 pubmed publisher
    ..We review how infection and inflammation can lead to host glycosylation changes, how host glycosylation changes can increase ..
  31. Pyo J, Park J, Park Y, Lee S, Ha Y, Lee S. Delta neutrophil index as a marker for differential diagnosis between flare and infection in febrile systemic lupus erythematosus patients. Lupus. 2013;22:1102-9 pubmed publisher
    ..of systemic lupus erythematosus (SLE), and because of this it is difficult to discriminate between SLE flare and infection. The delta neutrophil index (DNI), automatically determined by the ADVIA 2120 electronic cell analyzer, has been ..
  32. Ma Y, Chang H. Caspase work model during pathogen infection. Virol Sin. 2011;26:366-75 pubmed publisher
    ..These three modes are regulated by different inhibitors, and there may be a novel way to treat intracellular pathogen and autoimmune diseases based on the specific inhibitors. ..
  33. van den Berg L, Gringhuis S, Geijtenbeek T. An evolutionary perspective on C-type lectins in infection and immunity. Ann N Y Acad Sci. 2012;1253:149-58 pubmed publisher
    ..This review provides an update on the role of C-type lectins in HIV-1, mycobacterial, and Candida infections, and the coevolution of hosts and pathogens. ..
  34. Chaves F, Lee A, Nayak J, Richards K, Sant A. The utility and limitations of current Web-available algorithms to predict peptides recognized by CD4 T cells in response to pathogen infection. J Immunol. 2012;188:4235-48 pubmed publisher
    The ability to track CD4 T cells elicited in response to pathogen infection or vaccination is critical because of the role these cells play in protective immunity...
  35. Atladóttir H, Henriksen T, Schendel D, Parner E. Using maternally reported data to investigate the association between early childhood infection and autism spectrum disorder: the importance of data source. Paediatr Perinat Epidemiol. 2012;26:373-85 pubmed publisher
    ..We aimed to replicate these findings using maternal reports of childhood infection. We used the Danish National Birth Cohort consisting of 92 583 live singletons born from 1997 to 2003 in Denmark...
  36. Tiwari S, Pratyush D, Gupta B, Dwivedi A, Chaudhary S, Rayicherla R, et al. Prevalence and severity of vitamin D deficiency in patients with diabetic foot infection. Br J Nutr. 2013;109:99-102 pubmed publisher
    ..present research was to study the prevalence and severity of vitamin D deficiency in patients with diabetic foot infection. Patients were enrolled in two groups: diabetic patients with foot infection (n 125) as cases and diabetic ..
  37. Drakesmith H, Prentice A. Hepcidin and the iron-infection axis. Science. 2012;338:768-72 pubmed publisher
    ..We describe how hepcidin integrates signals from diverse physiological inputs, forming a key molecular bridge between iron trafficking and response to infection.
  38. Li J, Yang J, Huang J, Jiang D, Zhang F, Liu M, et al. Immunosuppression and the infection caused by gut mucosal barrier dysfunction in patients with early severe acute pancreatitis. Front Biosci (Landmark Ed). 2013;18:892-900 pubmed
    Few data are available on the relationship between immune response and the infection caused by gut mucosal barrier dysfunction in patients with severe acute pancreatitis (SAP)...
  39. Ouellet J, Ball C, Kortbeek J, Mack L, Kirkpatrick A. Bioprosthetic mesh use for the problematic thoracoabdominal wall: outcomes in relation to contamination and infection. Am J Surg. 2012;203:594-597 pubmed publisher
    ..Two patients presented recurrences (median follow-up = 126 days). The use of HADM for complex thoracoabdominal wall defects in contaminated or infected settings is a reliable option available for surgeons. ..
  40. Frazer L, Darville T, Chandra Kuntal K, Andrews C, Zurenski M, Mintus M, et al. Plasmid-cured Chlamydia caviae activates TLR2-dependent signaling and retains virulence in the guinea pig model of genital tract infection. PLoS ONE. 2012;7:e30747 pubmed publisher
    ..caviae. Furthermore, inflammatory pathology induced by infection of guinea pigs with CC13 was similar to that induced by GPIC, although we observed more rapid resolution of CC13 ..
  41. Kaech S, Cui W. Transcriptional control of effector and memory CD8+ T cell differentiation. Nat Rev Immunol. 2012;12:749-61 pubmed publisher
    During an infection, T cells can differentiate into multiple types of effector and memory T cells, which help to mediate pathogen clearance and provide long-term protective immunity...
  42. Piccinini A, Midwood K. Endogenous control of immunity against infection: tenascin-C regulates TLR4-mediated inflammation via microRNA-155. Cell Rep. 2012;2:914-26 pubmed publisher
    ..Tenascin-C is an extracellular matrix glycoprotein that is specifically induced upon injury and infection. Here, we show that its expression is required to generate an effective immune response to bacterial ..
  43. Luntamo M, Kulmala T, Cheung Y, Maleta K, Ashorn P. The effect of antenatal monthly sulphadoxine-pyrimethamine, alone or with azithromycin, on foetal and neonatal growth faltering in Malawi: a randomised controlled trial. Trop Med Int Health. 2013;18:386-97 pubmed publisher
    ..Adding azithromycin to the regimen appears to offer further benefits in reducing foetal and neonatal growth faltering. ..
  44. Tang L, Zhang H, Lei L, Gong S, Zhou Z, Baseman J, et al. Oviduct infection and hydrosalpinx in DBA1/j mice is induced by intracervical but not intravaginal inoculation with Chlamydia muridarum. PLoS ONE. 2013;8:e71649 pubmed publisher
    Intravaginal infection with C. muridarum in mice often results in hydrosalpinx similar to that found in women urogenitally infected with C. trachomatis, making the C...
  45. Janka G. Familial and acquired hemophagocytic lymphohistiocytosis. Annu Rev Med. 2012;63:233-46 pubmed publisher
    ..Treatment of HLH includes immune-suppressive and immune-modulatory agents, cytostatic drugs, and biological response modifiers. For patients with FHL, stem cell transplantation is indicated and can be curative. ..
  46. Zhang Y, Gu Y, Guo T, Li Y, Cai H. Perioperative immunonutrition for gastrointestinal cancer: a systematic review of randomized controlled trials. Surg Oncol. 2012;21:e87-95 pubmed publisher
    ..To improve the clinical outcome, immunonutrition (IN) was usually used in the patients undergoing elective gastrointestinal caner surgery. However, its effectiveness remains uncertain...
  47. MacMicking J. Interferon-inducible effector mechanisms in cell-autonomous immunity. Nat Rev Immunol. 2012;12:367-82 pubmed publisher
    ..induce the expression of hundreds of genes as part of an elaborate antimicrobial programme designed to combat infection in all nucleated cells - a process termed cell-autonomous immunity...
  48. Oakeshott P, Aghaizu A, Reid F, Howell Jones R, Hay P, Sadiq S, et al. Frequency and risk factors for prevalent, incident, and persistent genital carcinogenic human papillomavirus infection in sexually active women: community based cohort study. BMJ. 2012;344:e4168 pubmed publisher
    ..To investigate frequency and risk factors for prevalent, incident, and persistent carcinogenic human papillomavirus (HPV) in young women before the introduction of immunisation against HPV types 16 and 18 for schoolgirls...
  49. Maeda H. The link between infection and cancer: tumor vasculature, free radicals, and drug delivery to tumors via the EPR effect. Cancer Sci. 2013;104:779-89 pubmed publisher
    This review focuses primarily on my own research, including pathogenic mechanisms of microbial infection, vascular permeability in infection and tumors, and effects of nitric oxide (NO), superoxide anion radical (O??), and 8-..
  50. Scheffer K, Popa Wagner R, Florin L. Isolation and characterization of pathogen-bearing endosomes enable analysis of endosomal escape and identification of new cellular cofactors of infection. Methods Mol Biol. 2013;1064:101-13 pubmed publisher
    ..Here, we present detailed experimental instructions on isolation of endosomes after virus infection and their subsequent biomolecular characterization...
  51. Johnson R, Kerr M, Slaven J. Plac8-dependent and inducible NO synthase-dependent mechanisms clear Chlamydia muridarum infections from the genital tract. J Immunol. 2012;188:1896-904 pubmed publisher
    ..In vitro studies have shown that CD4 T cells terminate infection by upregulating epithelial inducible NO synthase (iNOS) transcription and NO production...
  52. Wong M, Ohrmalm L, Broliden K, Aust C, Hibberd M, Tolfvenstam T. Mannose-binding lectin 2 polymorphisms do not influence frequency or type of infection in adults with chemotherapy induced neutropaenia. PLoS ONE. 2012;7:e30819 pubmed publisher
    ..and from iatrogenic treatments for their underlying disease we investigated the role of MBL in susceptibility to infection. In this cross sectional, prospective study, blood samples obtained from 96 neutropaenic febrile episodes, ..
  53. Chico R, Mayaud P, Ariti C, Mabey D, Ronsmans C, Chandramohan D. Prevalence of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review. JAMA. 2012;307:2079-86 pubmed publisher
  54. Enouz S, Carrie L, Merkler D, Bevan M, Zehn D. Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection. J Exp Med. 2012;209:1769-79 pubmed
    ..Upon activation during an infection they cause autoimmunity and form memory cells...
  55. Fluri F, Morgenthaler N, Mueller B, Christ Crain M, Katan M. Copeptin, procalcitonin and routine inflammatory markers-predictors of infection after stroke. PLoS ONE. 2012;7:e48309 pubmed publisher
    Early predictors for the development of stroke-associated infection may identify patients at high risk and reduce post-stroke infection and mortality...
  56. Best J, Blair D, Knell J, Yang E, Mayya V, Doedens A, et al. Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nat Immunol. 2013;14:404-12 pubmed publisher
    After infection, many factors coordinate the population expansion and differentiation of CD8+ effector and memory T cells...
  57. Schiffer J, Corey L. Rapid host immune response and viral dynamics in herpes simplex virus-2 infection. Nat Med. 2013;19:280-90 pubmed publisher
    ..The fact that immune responses usually control viral replication in genital skin before lesions develop provides hope that enhancing such responses could lead to effective vaccines and immunotherapies. ..
  58. Muraki Y, Usui M, Isaji S, Mizuno S, Nakatani K, Yamada T, et al. Impact of CYP3A5 genotype of recipients as well as donors on the tacrolimus pharmacokinetics and infectious complications after living-donor liver transplantation for Japanese adult recipients. Ann Transplant. 2011;16:55-62 pubmed
    ..67, p=0.03). Preoperative assessment of CYP3A5 genotypes in both recipients and donors would be useful not only for predicting tacrolimus pharmacokinetics but also defining high-risk group of infectious complications after LDLT. ..
  59. Amulic B, Cazalet C, Hayes G, Metzler K, Zychlinsky A. Neutrophil function: from mechanisms to disease. Annu Rev Immunol. 2012;30:459-89 pubmed publisher
    ..of neutrophils not only as professional killers, but also as instructors of the immune system in the context of infection and inflammatory disease...
  60. Ducharme G, Lowe G, Goutagny R, Williams S. Early alterations in hippocampal circuitry and theta rhythm generation in a mouse model of prenatal infection: implications for schizophrenia. PLoS ONE. 2012;7:e29754 pubmed publisher
    ..To investigate this, we used a mouse model of prenatal infection with the viral mimic, polyriboinosinic-polyribocytidilic acid (poly I:C), a model based on epidemiological ..
  61. Puzik A, Rupp J, Tröger B, Gopel W, Herting E, Hartel C. Insulin-like growth factor-I regulates the neonatal immune response in infection and maturation by suppression of IFN-?. Cytokine. 2012;60:369-76 pubmed publisher
    ..Immunosuppression by IGF-I might be a key regulator of neonatal immune responses in infection and maturation...
  62. Amanna I, Hammarlund E, Lewis M, Slifka M. Impact of infection or vaccination on pre-existing serological memory. Hum Immunol. 2012;73:1082-6 pubmed publisher
    ..These immunizations provided the opportunity to determine if infection/vaccination and the resulting toll-like receptor stimulation would alter antigen-specific serological memory to ..
  63. Vicetti Miguel R, Reighard S, Chavez J, Rabe L, Maryak S, Wiesenfeld H, et al. Transient detection of Chlamydial-specific Th1 memory cells in the peripheral circulation of women with history of Chlamydia trachomatis genital tract infection. Am J Reprod Immunol. 2012;68:499-506 pubmed publisher
    Development of safe and effective Chlamydia trachomatis vaccines requires better understanding of the host immune responses elicited by natural infection.
  64. Mancino A, Habbeddine M, Johnson E, Luron L, Bebien M, Memet S, et al. I kappa B kinase alpha (IKK?) activity is required for functional maturation of dendritic cells and acquired immunity to infection. EMBO J. 2013;32:816-28 pubmed publisher
    ..This presents a unique role for IKK? in dampening inflammation while simultaneously promoting adaptive immunity that could have important implications for the development of new vaccine adjuvants and treatment of autoimmune diseases. ..
  65. Brabin L, Brabin B, Gies S. Influence of iron status on risk of maternal or neonatal infection and on neonatal mortality with an emphasis on developing countries. Nutr Rev. 2013;71:528-40 pubmed publisher
    b>Infection is a major cause of neonatal death in developing countries...
  66. van den Hoek H, Bos W, de Boer A, van de Garde E. Statins and prevention of infections: systematic review and meta-analysis of data from large randomised placebo controlled trials. BMJ. 2011;343:d7281 pubmed publisher
    ..b>Infection or infection related death. The first study selection yielded 632 trials...
  67. Ewald P, Swain Ewald H. Infection, mutation, and cancer evolution. J Mol Med (Berl). 2012;90:535-41 pubmed publisher
  68. Listing J, Gerhold K, Zink A. The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment. Rheumatology (Oxford). 2013;52:53-61 pubmed publisher
    RA is known to be associated with an increased risk of serious infection. Even more than 50 years ago, observational studies showed a greater than 2-fold increased risk of serious infection in RA...
  69. Mrazek F, Gallo J, Stahelova A, Petrek M. Coding variants of TLR2 and TLR4 genes do not substantially contribute to prosthetic joint infection. Inflamm Res. 2013;62:483-7 pubmed publisher
    Prosthetic joint infection (PJI) is a severe complication of total joint arthroplasty (TJA)...
  70. Andrew D, Cochrane M, Schripsema J, Ramsey K, Dando S, O Meara C, et al. The duration of Chlamydia muridarum genital tract infection and associated chronic pathological changes are reduced in IL-17 knockout mice but protection is not increased further by immunization. PLoS ONE. 2013;8:e76664 pubmed publisher
    ..We have compared (i) the course of natural genital tract C. muridarum infection, (ii) the development of oviduct pathology and (iii) the development of vaccine-induced immunity against ..
  71. Young S, Banza L, Hallan G, Beniyasi F, Manda K, Munthali B, et al. Complications after intramedullary nailing of femoral fractures in a low-income country. Acta Orthop. 2013;84:460-7 pubmed publisher
    Some surgeons believe that internal fixation of fractures carries too high a risk of infection in low-income countries (LICs) to merit its use there...
  72. Shapiro G, Fraser W, Frasch M, Séguin J. Psychosocial stress in pregnancy and preterm birth: associations and mechanisms. J Perinat Med. 2013;41:631-45 pubmed publisher
    ..Culture-independent characterization of the vaginal microbiome and noninvasive monitoring of cholinergic activity represent two exciting frontiers in this research. ..
  73. Jackson D, Gern J, Lemanske R. The contributions of allergic sensitization and respiratory pathogens to asthma inception. J Allergy Clin Immunol. 2016;137:659-65; quiz 666 pubmed publisher
  74. Folk A, Cotoraci C, Baltă C, Suciu M, Herman H, Boldura O, et al. Evaluation of Hepatotoxicity with Treatment Doses of Flucytosine and Amphotericin B for Invasive Fungal Infections. Biomed Res Int. 2016;2016:5398730 pubmed publisher
    Invasive fungal infection is a well-known cause of morbidity and mortality in immunocompromised patients...
  75. Potluri K, Holt D, Hou S. Neurologic complications in renal transplantation. Handb Clin Neurol. 2014;121:1245-55 pubmed publisher
    ..Clinical presentation of central nervous system infection in transplant recipients can be different from the normal population as the anti-inflammatory effects of ..
  76. Torres L, Rhenals A, Jiménez A, Ramírez Villalobos D, Urióstegui R, Piña M, et al. [Intentional search and reclassification of maternal deaths in Mexico: The effect on the distribution of causes]. Salud Publica Mex. 2014;56:333-47 pubmed
  77. Arakaki R. Sodium-glucose cotransporter-2 inhibitors and genital and urinary tract infections in type 2 diabetes. Postgrad Med. 2016;128:409-17 pubmed publisher
  78. Alcaide M, Strbo N, Romero L, Jones D, Rodriguez V, Arheart K, et al. Bacterial Vaginosis Is Associated with Loss of Gamma Delta T Cells in the Female Reproductive Tract in Women in the Miami Women Interagency HIV Study (WIHS): A Cross Sectional Study. PLoS ONE. 2016;11:e0153045 pubmed publisher
    Bacterial vaginosis (BV) is the most common female reproductive tract infection and is associated with an increased risk of acquiring and transmitting HIV by a mechanism that is not well understood...
  79. Deer T, Provenzano D, Hanes M, Pope J, Thomson S, Russo M, et al. The Neurostimulation Appropriateness Consensus Committee (NACC) Recommendations for Infection Prevention and Management. Neuromodulation. 2017;20:31-50 pubmed publisher
    ..convened an international panel of well published and diverse physicians to examine the best practices for infection mitigation and management in patients undergoing neurostimulation...
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    ..Another option for implant infection management has emerged in which the soft tissue infection is neutralized, the implant is removed, the surgical ..
  81. Setacci C, Müller Hülsbeck S, Jamar F. Common diagnostic flowcharts in vascular and endovascular surgery. Q J Nucl Med Mol Imaging. 2014;58:46-54 pubmed
    Vascular and endovascular procedures are typically very "clean" procedures, with a very low infection rate. However, these complications, although rare, are unfortunately associated with a high rate of morbidity and mortality...
  82. Jutte P, Lazzeri E, Sconfienza L, Cassar Pullicino V, Trampuz A, Petrosillo N, et al. Diagnostic flowcharts in osteomyelitis, spondylodiscitis and prosthetic joint infection. Q J Nucl Med Mol Imaging. 2014;58:2-19 pubmed
    ..In this report the proceedings of this consensus meeting, including the proposed flowcharts for diagnosis, are published. ..
  83. De Gregorio P, Juárez Tomás M, Leccese Terraf M, Nader Macias M. In vitro and in vivo effects of beneficial vaginal lactobacilli on pathogens responsible for urogenital tract infections. J Med Microbiol. 2014;63:685-96 pubmed publisher
    ..However, as these effects were not evidenced in the murine model used, further animal studies under different experimental conditions should be conducted to evaluate the preventive effect of Lb against challenge with S. agalactiae. ..
  84. Ma L, Chen R, Liu F, Li Y, Wu Z, Zhong W, et al. Reduced NK cell percentage at birth is associated with late onset infection in very preterm neonates. Scand J Immunol. 2014;80:50-6 pubmed publisher
    Immune status in the early life of preterm infants and its association with late onset infection has not been fully described...
  85. Lamkanfi M, Dixit V. Mechanisms and functions of inflammasomes. Cell. 2014;157:1013-22 pubmed publisher
    ..Activation of caspases 1 and 11 in canonical and noncanonical inflammasomes, respectively, also protects against infection by triggering pyroptosis, a proinflammatory and lytic mode of cell death...
  86. Yang W, Cai X, Han X, Ji L. DPP-4 inhibitors and risk of infections: a meta-analysis of randomized controlled trials. Diabetes Metab Res Rev. 2016;32:391-404 pubmed publisher
    ..Out of 2181 studies, 74 studies were finally included. The risk of overall infection for DPP-4 inhibitors treatment was comparable to placebo (odds ratio (OR)?=?0...
  87. Franklin J, Schneeweiss S, Solomon D. Assessment of Confounders in Comparative Effectiveness Studies From Secondary Databases. Am J Epidemiol. 2017;185:474-478 pubmed publisher
    ..Thus, investigators should carefully consider the timing of confounder measurements relative to exposure initiation and the rate of change in the confounder in order to choose the most relevant measure for each patient. ..
  88. Kanayama M, Xu S, Danzaki K, Gibson J, Inoue M, Gregory S, et al. Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin. Nat Immunol. 2017;18:973-984 pubmed publisher
    ..Here we found that osteopontin (OPN) skewed this balance during pathogenic conditions such as infection and autoimmunity...
  89. Nathan C. Kunkel Lecture: Fundamental immunodeficiency and its correction. J Exp Med. 2017;214:2175-2191 pubmed publisher
    ..immunodeficiency" is the inability of the encoded immune system to protect an otherwise healthy host from every infection that could threaten its life...
  90. Berenson J, Hilger J, Yellin O, Boccia R, Matous J, Dressler K, et al. A phase 1/2 study of oral panobinostat combined with melphalan for patients with relapsed or refractory multiple myeloma. Ann Hematol. 2014;93:89-98 pubmed publisher
    ..Panobinostat?+?melphalan appears to have tolerability issues in a dosing regimen capable of producing a response. Care must be taken to balance tolerability and efficacy with this combination. ..
  91. Mizuno S, Muraki Y, Nakatani K, Tanemura A, Kuriyama N, Ohsawa I, et al. Immunological aspects in late phase of living donor liver transplant patients: usefulness of monitoring peripheral blood CD4+ adenosine triphosphate activity. Clin Dev Immunol. 2013;2013:982163 pubmed publisher
    ..The mean ATP level of the IMK assay was significantly lower in the patients with infection including recurrence of hepatitis C (HCV) (n = 10) than in those without infection (n = 39): 185 versus 350 ng/..
  92. Avery R. Update on infections in composite tissue allotransplantation. Curr Opin Organ Transplant. 2013;18:659-64 pubmed publisher
    ..More descriptions of infection risk in the late posttransplant period will be helpful, as more composite tissue allotransplantation recipients ..