Research Topics
Genomes and Genes
| staphylococcal infectionsSummarySummary: Infections with bacteria of the genus STAPHYLOCOCCUS. Webpages
www.health.vic.gov.au/ideas/bluebook/staphylococcal.htm blue book: ideas - victorian government health information, australiawww.health.vic.gov.au/ideas/bluebook/index.htm staphylococcal infections (print versionwww.nlm.nih.gov/medlineplus/print/staphylococcalinfections.h ... cdc - increasing resistance to vancomycin and other glycopeptides in staphylococcus aureuswww.cdc.gov/ncidod/eid/vol7no2/tenover.htm channing laboratory - jean c. lee, phdwww.channing.harvard.edu/lee_j.htm staphylococcal infections: medlinepluswww.nlm.nih.gov/medlineplus/staphylococcalinfections.html genome analysis center/staphylococcus aureus n315www.bio.nite.go.jp/ngac/e/n315-e.html furunculosis clinical resourcesguam-dl.slis.ua.edu/clinical/infectious/bybodysystem/dermato ... curso sepsis grave: capítulo 7remi.uninet.edu/2004/08/REMIC07.htm furunculosis clinical resourcescchs-dl.slis.ua.edu/clinical/infectious/bybodysystem/dermato ... ol>Research Grants Analysis of VraSR and VraSR regulated gene expression in Staphylococcus aureusRadheshyam K Jayaswal; Fiscal Year: 2008 PENICILLIN INTERACTIVE PROTEINS OF STAPHYLOCOCCUS AUREUSHenry F Chambers; Fiscal Year: 2003 Novel antibacterial agents for treatment of TularemiaNachum Kaplan; Fiscal Year: 2004 Host Response in S. aureus Infections: Role of T cellsArthur O Tzianabos; Fiscal Year: 2006 Nanocarrier with metal bridge for affinity based delivery of metal binding peptidElijah M Bolotin; Fiscal Year: 2008 Quorum sensing and Staphylococcus aureus pathogenesisNaomi Balaban; Fiscal Year: 2005 A longitudinal Study of CA-MRSA Nasal Colonization in College Sports ParticipantsClarence Buddy Creech; Fiscal Year: 2008 PEGylated Lysostaphin for Staphylococcal InfectionsJOHN F KOKAI KUN; Fiscal Year: 2004 Regulation of Virulence by luxS in Staphylococcus aureusMOHAMED OMAR ELASRI; Fiscal Year: 2005 DYNAMIC PLATELET - STAPHYLOCOCCAL INTERACTIONSJulia M Ross; Fiscal Year: 2004 ol>Publications Molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream isolates in urban DetroitThea Chua Henry Ford Health System, Wayne State University School of Medicine, Detroit, Michigan 48202, USA J Clin Microbiol 46:2345-52 Comparison of community-acquired methicillin-resistant Staphylococcus aureus bacteremia to other staphylococcal species in a neonatal intensive care unitJacob Kuint Neonatal Department, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Eur J Pediatr 166:319-25 Are community-associated methicillin-resistant Staphylococcus aureus (MRSA) strains replacing traditional nosocomial MRSA strains?Kyle J Popovich Division of Infectious Disease, Department of Medicine, Rush University Medical Center, and Division of Infectious Disease, Department of Medicine, Stroger Hospital of Cook County, Chicago, Illinois 60612, USA Clin Infect Dis 46:787-94 Epidemiology and typing of Staphylococcus aureus strains isolated from bloodstream infectionsNathalie van der Mee Marquet Departement de Microbiologie et Moléculaire, UFR Médecine, Tours Cedex, France J Clin Microbiol 42:5650-7 Comparative in vitro activity of quinupristin/dalfopristin and seven other antimicrobials against methicillin-susceptible and methicillin-resistant nosocomial Staphylococcus aureus bloodstream isolatesP Nikolaidis First Department of Internal Medicine, Infectious Diseases Division, University Hospital AHEPA, Thessaloniki, Greece J Chemother 14:544-6 Methicillin-resistant versus methicillin-sensitive Staphylococcus aureus infective endocarditisE E Hill Department of Internal Medicine Infectious Diseases, K U Leuven, University Hospital Gasthuisberg, Leuven, Belgium Eur J Clin Microbiol Infect Dis 27:445-50 Staphylococcus aureus: the new adventures of a legendary pathogenSusan J Rehm Department of Infectious Disease, Cleveland Clinic Foundation, OH 44195, USA Cleve Clin J Med 75:177-80, 183-6, 190-2 Activities of antistaphylococcal antibiotics towards the extracellular and intraphagocytic forms of Staphylococcus aureus isolates from a patient with persistent bacteraemia and endocarditisS Lemaire Unité de Pharmacologie Cellulaire et Moléculaire, Université Catholique de Louvain, Bruxelles, Belgium Clin Microbiol Infect 14:766-77 Three-year survey of community-acquired methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin in a French university hospitalT Naas Service de Bactériologie virologie hygiène, Hôpital de Bicêtre, Assistance Publique, Hôpitaux de Paris, Faculté de Médecine Paris Sud, Le Kremlin Bicêtre, France J Hosp Infect 61:321-9 The emergence and importation of diverse genotypes of methicillin-resistant Staphylococcus aureus (MRSA) harboring the Panton-Valentine leukocidin gene (pvl) reveal that pvl is a poor marker for community-acquired MRSA strains in IrelandAngela S Rossney ol>National MRSA Reference Laboratory, St James s Hospital, James s St, Dublin 8, Ireland J Clin Microbiol 45:2554-63 | Scientific Experts
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Detail Information
Webpages
- staphylococcal infections- blue book: ideas - victorian government
www.health.vic.gov.au/ideas/bluebook/staphylococcal.htm
blue book: ideas - victorian government health information, australiawww.health.vic.gov.au/ideas/bluebook/index.htm
staphylococcal infections (print versionwww.nlm.nih.gov/medlineplus/print/staphylococcalinfections.h ...
cdc - increasing resistance to vancomycin and other glycopeptides in staphylococcus aureuswww.cdc.gov/ncidod/eid/vol7no2/tenover.htm
channing laboratory - jean c. lee, phdwww.channing.harvard.edu/lee_j.htm
staphylococcal infections: medlinepluswww.nlm.nih.gov/medlineplus/staphylococcalinfections.html
genome analysis center/staphylococcus aureus n315www.bio.nite.go.jp/ngac/e/n315-e.html
furunculosis clinical resourcesguam-dl.slis.ua.edu/clinical/infectious/bybodysystem/dermato ...
curso sepsis grave: capítulo 7remi.uninet.edu/2004/08/REMIC07.htm
furunculosis clinical resourcescchs-dl.slis.ua.edu/clinical/infectious/bybodysystem/dermato ...
publication: vascular prosthetic infection with staphylococcus epidermidis: experimental study of pathogenesis and therapywww.fred.psu.edu/ds/retrieve/fred/publication/2921795
medline publication: evaluation of three techniques for documenting staphylococcus epidermidis vascular prosthetic graft infectionswww.fred.psu.edu/ds/retrieve/fred/medlinepub/1992873
radiology in ped emerg med, vol 2, case 5www.hawaii.edu/medicine/pediatrics/pemxray/v2c05.html
genomic research laboratory geneva - staphylococcus aureus intracellular survivalwww.genomic.ch/research_intern.php
staphylococcal infections clinical resourcescapstoneclinic-dl.slis.ua.edu/clinical/infectious/byorganism ...
nosocomial infections clinical resourcescapstoneclinic-dl.slis.ua.edu/clinical/infectious/nosocomial ...
nosocomial infections clinical resourcesfsumed-dl.slis.ua.edu/clinical/infectious/nosocomial.htm
genomic research laboratory geneva - staphylococcus aureus biofilmswww.genomic.ch/research_biofilm.php
staphylococcal infections patient/family resourcesdalemc-dl.slis.ua.edu/patientinfo/infectious/byorganism/bact ...
rifampinwww.umm.edu/altmed/drugs/rifampin-112000.htm
staphylococcal infections clinical resourcesfsumed-dl.slis.ua.edu/clinical/infectious/byorganism/bacteri ...
staphylococcus biofilm picture (hardin md / cdcwww.lib.uiowa.edu/hardin/md/cdc/staph/sem3.html
staphylococcal infections patient/family resourcesahecpinebluff-dl.slis.ua.edu/patientinfo/infectious/byorgani ...
staphylococcal infectionsbuchta.lib.bioinfo.pl/meid:18216
staphylococcal infections clinical resourcesbaptistnashville-dl.slis.ua.edu/clinical/infectious/byorgani ...
hillier, andrew :: the college of veterinary medicine at the ohio state universitywww.vet.ohio-state.edu/AndrewHillier.htm
folliculitis clinical resourcesguam-dl.slis.ua.edu/clinical/infectious/bybodysystem/dermato ...
infectious arthritis clinical resourcescapstoneclinic-dl.slis.ua.edu/clinical/infectious/bybodysyst ...
ol>Research Grants
Analysis of VraSR and VraSR regulated gene expression in Staphylococcus aureusRadheshyam K Jayaswal; Fiscal Year: 2008
..Thus, there is an urgent need for the development of new antimicrobial agents to treat staphylococcal infections. In our lab we have been using various approaches such as isolation and characterization of laboratory-..
PENICILLIN INTERACTIVE PROTEINS OF STAPHYLOCOCCUS AUREUSHenry F Chambers; Fiscal Year: 2003
..of penicillins and beta-lactam antibiotics is the real problem, as these are drug of choice to treat staphylococcal infections. The objective of this research is to further knowledge of mechanisms of methicillin resistance...
Novel antibacterial agents for treatment of TularemiaNachum Kaplan; Fiscal Year: 2004
..Phase II clinical trials are proposed in Years 4 and 5, as a narrow spectrum agent for the treatment of Staphylococcal infections. This funding will assure rapid progress of this new class of antibacterial agent through the last ..
Host Response in S. aureus Infections: Role of T cellsArthur O Tzianabos; Fiscal Year: 2006
..b>Staphylococcal infections occur most frequently when mucosal barriers are breached, following insertion of a foreign body, or in ..
Nanocarrier with metal bridge for affinity based delivery of metal binding peptidElijah M Bolotin; Fiscal Year: 2008
..lysostaphin in an optimal infection site-directed delivery system for the treatment of invasive staphylococcal infections. Public Health Relevance: The available therapies for antibiotic resistant S...
Quorum sensing and Staphylococcus aureus pathogenesisNaomi Balaban; Fiscal Year: 2005
..understand how virulence is regulated in Staphylococcus aureus and to further develop immunotherapy to staphylococcal infections. S...
A longitudinal Study of CA-MRSA Nasal Colonization in College Sports ParticipantsClarence Buddy Creech; Fiscal Year: 2008
..Treatment of staphylococcal infections has become more challenging due to the emergence of community-associated methicillin-resistant S...
PEGylated Lysostaphin for Staphylococcal InfectionsJOHN F KOKAI KUN; Fiscal Year: 2004
..aureus infections (as a nasal cream) and in treating topical and systemic S. aureus infections, including S. aureus endocarditis...
Regulation of Virulence by luxS in Staphylococcus aureusMOHAMED OMAR ELASRI; Fiscal Year: 2005
..Our goal is to fill this gap as a prerequisite to developing therapeutic protocols for treatment of staphylococcal infections. In the proposed research, the hypothesis is that luxS system regulates the expression of virulence ..
DYNAMIC PLATELET - STAPHYLOCOCCAL INTERACTIONSJulia M Ross; Fiscal Year: 2004
..of platelet activation, blood components, blood flow, and bacteria in the development of blood-born staphylococcal infections. A long-term goal of this work is to investigate the interrelationship between thrombogenesis and ..
Regulation of S. aureus biofilm by RbfChia Y Lee; Fiscal Year: 2008
..b>Staphylococcal infections have become more difficult to treat due to the emergence of antibiotic resistance strains...
Regulation of S. aureus biofilm by RbfChia Y Lee; Fiscal Year: 2007
..b>Staphylococcal infections have become more difficult to treat due to the emergence of antibiotic resistance strains...
Computational Assembly of Beta Barrel Membrane ProteinJie Liang; Fiscal Year: 2008
..hospital-acquired pneumonia due to gram-negative bacteria, meningococcal meningitis, anthrax, and staphylococcal infections such as surgical wound and burn infections...
Computational Assembly of Beta Barrel Membrane ProteinJie Liang; Fiscal Year: 2007
..hospital-acquired pneumonia due to gram-negative bacteria, meningococcal meningitis, anthrax, and staphylococcal infections such as surgical wound and burn infections...
ol>Publications
Molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream isolates in urban DetroitThea Chua
Henry Ford Health System, Wayne State University School of Medicine, Detroit, Michigan 48202, USA
J Clin Microbiol 46:2345-52
Henry Ford Health System, Wayne State University School of Medicine, Detroit, Michigan 48202, USA
J Clin Microbiol 46:2345-52
..Infection control measures should focus not only on prevention of the spread of community strains in the hospital but also prevention of the spread of hospital strains associated with VRSA into the community...
Comparison of community-acquired methicillin-resistant Staphylococcus aureus bacteremia to other staphylococcal species in a neonatal intensive care unitJacob Kuint
Neonatal Department, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Eur J Pediatr 166:319-25
Neonatal Department, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Eur J Pediatr 166:319-25
..One possible explanation for this observation is that the CA-MRSA outbreak strain did not contain the pvl-gene, which has been suggested to be a significant virulence factor...
Are community-associated methicillin-resistant Staphylococcus aureus (MRSA) strains replacing traditional nosocomial MRSA strains?Kyle J Popovich
Division of Infectious Disease, Department of Medicine, Rush University Medical Center, and Division of Infectious Disease, Department of Medicine, Stroger Hospital of Cook County, Chicago, Illinois 60612, USA
Clin Infect Dis 46:787-94
Division of Infectious Disease, Department of Medicine, Rush University Medical Center, and Division of Infectious Disease, Department of Medicine, Stroger Hospital of Cook County, Chicago, Illinois 60612, USA
Clin Infect Dis 46:787-94
..For most risk factors and outcomes, patients infected with CG and HG strains were similar, suggesting that, thus far, CG strains are behaving like their traditional hospital-associated counterparts...
Epidemiology and typing of Staphylococcus aureus strains isolated from bloodstream infectionsNathalie van der Mee Marquet
Departement de Microbiologie et Moléculaire, UFR Médecine, Tours Cedex, France
J Clin Microbiol 42:5650-7
Departement de Microbiologie et Moléculaire, UFR Médecine, Tours Cedex, France
J Clin Microbiol 42:5650-7
....
Comparative in vitro activity of quinupristin/dalfopristin and seven other antimicrobials against methicillin-susceptible and methicillin-resistant nosocomial Staphylococcus aureus bloodstream isolatesP Nikolaidis
First Department of Internal Medicine, Infectious Diseases Division, University Hospital AHEPA, Thessaloniki, Greece
J Chemother 14:544-6
First Department of Internal Medicine, Infectious Diseases Division, University Hospital AHEPA, Thessaloniki, Greece
J Chemother 14:544-6
..5mg/L. According to these results, quinupristin-dalfopristin shows promising in-vitro activity and may be a welcome alternative treatment for methicillin-resistant staphylococcal infections, resulting in reduced use of glycopeptides.
Methicillin-resistant versus methicillin-sensitive Staphylococcus aureus infective endocarditisE E Hill
Department of Internal Medicine Infectious Diseases, K U Leuven, University Hospital Gasthuisberg, Leuven, Belgium
Eur J Clin Microbiol Infect Dis 27:445-50
Department of Internal Medicine Infectious Diseases, K U Leuven, University Hospital Gasthuisberg, Leuven, Belgium
Eur J Clin Microbiol Infect Dis 27:445-50
..Denial of surgery because of local or general factors in patients that meet criteria for surgical intervention in acute IE is prognostically ominous...
Staphylococcus aureus: the new adventures of a legendary pathogenSusan J Rehm
Department of Infectious Disease, Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 75:177-80, 183-6, 190-2
Department of Infectious Disease, Cleveland Clinic Foundation, OH 44195, USA
Cleve Clin J Med 75:177-80, 183-6, 190-2
..Another worrisome trend is increasing resistance to vancomycin (Vancocin)...
Activities of antistaphylococcal antibiotics towards the extracellular and intraphagocytic forms of Staphylococcus aureus isolates from a patient with persistent bacteraemia and endocarditisS Lemaire
Unité de Pharmacologie Cellulaire et Moléculaire, Université Catholique de Louvain, Bruxelles, Belgium
Clin Microbiol Infect 14:766-77
Unité de Pharmacologie Cellulaire et Moléculaire, Université Catholique de Louvain, Bruxelles, Belgium
Clin Microbiol Infect 14:766-77
..Determination of the intracellular susceptibility of S. aureus, combined with improved methods of diagnosis, could be useful when dealing with persistent staphylococcal infections and could improve therapy.
Three-year survey of community-acquired methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin in a French university hospitalT Naas
Service de Bactériologie virologie hygiène, Hôpital de Bicêtre, Assistance Publique, Hôpitaux de Paris, Faculté de Médecine Paris Sud, Le Kremlin Bicêtre, France
J Hosp Infect 61:321-9
Service de Bactériologie virologie hygiène, Hôpital de Bicêtre, Assistance Publique, Hôpitaux de Paris, Faculté de Médecine Paris Sud, Le Kremlin Bicêtre, France
J Hosp Infect 61:321-9
..The incidence at Bicêtre Hospital was 0.8% of all S. aureus and 2% of all MRSA isolated. Our data indicate that these MRSA isolates might become hospital acquired...
The emergence and importation of diverse genotypes of methicillin-resistant Staphylococcus aureus (MRSA) harboring the Panton-Valentine leukocidin gene (pvl) reveal that pvl is a poor marker for community-acquired MRSA strains in IrelandAngela S Rossney
National MRSA Reference Laboratory, St James s Hospital, James s St, Dublin 8, Ireland
J Clin Microbiol 45:2554-63
National MRSA Reference Laboratory, St James s Hospital, James s St, Dublin 8, Ireland
J Clin Microbiol 45:2554-63
..3, and the remaining 11 isolates could not be subtyped. This study demonstrates that pvl is not a reliable marker for CA-MRSA in Ireland and reveals the emergence and importation of diverse genotypes of pvl-positive MRSA in Ireland...
Comparisons of community-associated methicillin-resistant Staphylococcus aureus (MRSA) and hospital-associated MSRA infections in Sacramento, CaliforniaHsin Huang
Department of Infectious Disease, University of California, Davis, Medical Center, 4150 V Street, PSSB, G500, Sacramento, CA 95817, USA
J Clin Microbiol 44:2423-7
Department of Infectious Disease, University of California, Davis, Medical Center, 4150 V Street, PSSB, G500, Sacramento, CA 95817, USA
J Clin Microbiol 44:2423-7
..This strain originated in the community and is not related to MRSA strains from healthcare settings. Injecting drug users could be a major reservoir for CA-MRSA transmission...
[Resistance to antibiotics of Staphylococcus aureus responsible of osteoarticular infections]J Raymond
Université Renée Descartes, Service de Bactériologie, Hôpital Cochin, 27 r Fbg St Jacques 75014 Paris, France
Arch Pediatr 14:S97-S101
Université Renée Descartes, Service de Bactériologie, Hôpital Cochin, 27 r Fbg St Jacques 75014 Paris, France
Arch Pediatr 14:S97-S101
..It is now established that CA-MRSA are pathogens present all over the world. It thus became necessary to look after the epidemiology of these virulent strains...
Sporadic "transitional" community-associated methicillin-resistant Staphylococcus aureus strains from health care facilities in the United StatesJennifer M Brady
Molecular Microbiology Laboratory, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
J Clin Microbiol 45:2654-61
Molecular Microbiology Laboratory, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
J Clin Microbiol 45:2654-61
..The potential role of PVL-carrying phages and plasmids in the success of CA-MRSA clones has been discussed...
Emergence of community-associated methicillin-resistant Staphylococcus aureus USA 300 clone as a cause of health care-associated infections among patients with prosthetic joint infectionsEkaterina V Kourbatova
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
Am J Infect Control 33:385-91
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
Am J Infect Control 33:385-91
..methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as an important cause of staphylococcal infections, but there have been little data on whether CA-MRSA causes health care-associated infections...
Prevalence of SCCmec type IV in nosocomial bloodstream isolates of methicillin-resistant Staphylococcus aureusPriscila de A Trindade
Department of Infectious Diseases, LIM 54, Hospital das Clinicas, University of Sao Paulo, Rua Harmonia 564/52, São Paulo-SP 05435000, Brazil
J Clin Microbiol 43:3435-7
Department of Infectious Diseases, LIM 54, Hospital das Clinicas, University of Sao Paulo, Rua Harmonia 564/52, São Paulo-SP 05435000, Brazil
J Clin Microbiol 43:3435-7
..Molecular typing demonstrated four patterns, with one predominant pattern. Although usually community acquired, SCCmec type IV in our setting is clearly nosocomial...
Virulence characteristics of community-associated Staphylococcus aureus and in vitro activities of moxifloxacin alone and in combination against community-associated and healthcare-associated meticillin-resistant and -susceptible S. aureusEllie J C Goldstein
R M Alden Research Laboratory, Santa Monica, CA 90404, USA
J Med Microbiol 57:452-6
R M Alden Research Laboratory, Santa Monica, CA 90404, USA
J Med Microbiol 57:452-6
..The FICI values for doxycycline were 3-6 for 32/34 strains, indicating antagonism, suggesting that it should not be used in combination with moxifloxacin...
Resistance to methicillin and other antimicrobials among community-acquired and nosocomial Staphylococcus aureus strains in a pediatric teaching hospital in Salvador, Northeast BrazilCristiana M Nascimento Carvalho
Department of Pediatrics, School of Medicine, Federal University of Bahia UFBA, Salvador, Bahia, Brazil
Microb Drug Resist 14:129-31
Department of Pediatrics, School of Medicine, Federal University of Bahia UFBA, Salvador, Bahia, Brazil
Microb Drug Resist 14:129-31
..9% vs. 4.9%, p<0.001). Resistance to other antimicrobials was more common among NI-MRSA compared with CA-MRSA. Although at a low rate, CA-MRSA has occurred among children, in this region...
Community- and health care-associated methicillin-resistant Staphylococcus aureus: a comparison of molecular epidemiology and antimicrobial activities of various agentsBrian T Tsuji
Anti Infective Research Laboratory, Department of Pharmacy Practice, Wayne State University, MI 48201, USA
Diagn Microbiol Infect Dis 58:41-7
Anti Infective Research Laboratory, Department of Pharmacy Practice, Wayne State University, MI 48201, USA
Diagn Microbiol Infect Dis 58:41-7
..Further studies are warranted against a larger number of molecularly defined, geographically diverse CAMRSA to confirm these findings...
Staphylococcal cassette chromosome mec and Panton-Valentine leukocidin characterization of methicillin-resistant Staphylococcus aureus clonesShannon M Moroney
Esoteric Testing, Department of Pathology, Tampa General Hospital, P O Box 1289, Tampa, Florida 33601, USA
J Clin Microbiol 45:1019-21
Esoteric Testing, Department of Pathology, Tampa General Hospital, P O Box 1289, Tampa, Florida 33601, USA
J Clin Microbiol 45:1019-21
..CA-MRSA isolates carried the SCCmec type IV complex, and most were PVL positive. The HA-MRSA isolates carried the SCCmec type II complex and did not harbor the PVL genes...
Transmission and epidemiology of MRSA: current perspectivesMaggi Banning
The School of Health and Social Sciences, Middlesex University, Archway Campus, London
Br J Nurs 14:548-51, 554
The School of Health and Social Sciences, Middlesex University, Archway Campus, London
Br J Nurs 14:548-51, 554
....
Hospital transmission of community-acquired methicillin-resistant Staphylococcus aureus among postpartum womenLisa Saiman
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Clin Infect Dis 37:1313-9
Department of Pediatrics, Columbia University, New York, New York 10032, USA
Clin Infect Dis 37:1313-9
..We report that MW2, which was previously limited to the midwestern United States, has spread to the northeastern United States and has become a health care-associated pathogen...
Molecular epidemiology of community- and health care-associated methicillin-resistant Staphylococcus aureus in Manitoba, CanadaJohn L Wylie
Cadham Provincial Public Health Laboratory, Manitoba Health, P O Box 8450, 750 William Ave, Winnipeg, Manitoba, R3C 3Y1
J Clin Microbiol 43:2830-6
Cadham Provincial Public Health Laboratory, Manitoba Health, P O Box 8450, 750 William Ave, Winnipeg, Manitoba, R3C 3Y1
J Clin Microbiol 43:2830-6
..Mapping of specific CA-MRSA types over successive 5-year periods showed rapid temporal shifts in prevalence in different parts of the province...
Community-acquired methicillin-resistant Staphylococcus aureus in children in northern TaiwanYin-Hua Fang
Department of Pediatrics, Min-Sheng General Hospital, Taoyuan, Taiwan, ROC
J Microbiol Immunol Infect 37:29-34
Department of Pediatrics, Min-Sheng General Hospital, Taoyuan, Taiwan, ROC
J Microbiol Immunol Infect 37:29-34
..Our data suggest an increasing role of MRSA as a community pathogen in previously healthy children. Infection control strategies for both hospital and community should be re-evaluated...
Comparison of genetic backgrounds of methicillin-resistant and -susceptible Staphylococcus aureus isolates from Portuguese hospitals and the communityM Aires de Sousa
Laboratório de Genética Molecular, Instituto de Tecnologia QuÃmica e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal
J Clin Microbiol 43:5150-7
Laboratório de Genética Molecular, Instituto de Tecnologia QuÃmica e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal
J Clin Microbiol 43:5150-7
..Furthermore, we provide evidence that the introduction of SCCmec into sensitive clones is most likely a relatively infrequent event that seems to depend not exclusively on the presence of a successful MSSA lineage...
Spread of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) in hospitals in Taipei, Taiwan in 2005, and comparison of its drug resistance with previous hospital-acquired MRSATomomi Takano
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan, and National Taiwan University Hospital, Taipei, Taiwan
Microbiol Immunol 51:627-32
Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan, and National Taiwan University Hospital, Taipei, Taiwan
Microbiol Immunol 51:627-32
..The data suggests that although PVL+ CA-MRSA is isolated at a high incidence from hospitals in Taipei, the drug resistance is mostly selected in the community and less prominent compared with previous PVL- hospital-acquired MRSA...
Prevalence of inducible clindamycin resistance among community- and hospital-associated Staphylococcus aureus isolatesMukesh Patel
Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
J Clin Microbiol 44:2481-4
Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
J Clin Microbiol 44:2481-4
..Due to the low prevalence of MLSBi among CA-MRSA isolates, clindamycin remains a useful option for outpatient therapy...
Antimicrobial susceptibility and clonal relatedness between community- and hospital-acquired methicillin-resistant Staphylococcus aureus from blood culturesSook In Jung
Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Republic of Korea
J Microbiol 44:336-43
Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Republic of Korea
J Microbiol 44:336-43
..This study suggests that, although the CA-MRSA blood isolates showed diverse PFGE and antimicrobial resistance patterns, some of these isolates may have originated from the HA-MRSA strains...
In vitro activity of daptomycin against multidrug-resistant Staphylococcus aureus and S. aureus with known virulence factors, including community-acquired methicillin-resistant isolatesDiane M Anastasiou
Cubist Pharmaceuticals Inc, Lexington, MA 02421, USA
Diagn Microbiol Infect Dis 61:339-42
Cubist Pharmaceuticals Inc, Lexington, MA 02421, USA
Diagn Microbiol Infect Dis 61:339-42
..aureus with known virulence genes. All isolates were inhibited at <or=1 microg/mL, suggesting that daptomycin has excellent activity against both hospital-acquired and community-acquired S. aureus isolates...
[Methicillin-resistant Staphylococcus aureus (MRSA) in the community]A G Vonk
VU Medisch Centrum, afd Medische Microbiologie en Infectiepreventie, Postbus 7057, 1007 MB, Amsterdam
Ned Tijdschr Geneeskd 151:401-7
VU Medisch Centrum, afd Medische Microbiologie en Infectiepreventie, Postbus 7057, 1007 MB, Amsterdam
Ned Tijdschr Geneeskd 151:401-7
..In order to prevent and control CA-MRSA outbreaks in the community successfully, the restrictive Dutch antibiotic policy must be followed with strict infection prevention measures...
Bactericidal activity of orally available agents against methicillin-resistant Staphylococcus aureusAnjum S Kaka
Section of Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
J Antimicrob Chemother 58:680-3
Section of Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
J Antimicrob Chemother 58:680-3
..No differences in bactericidal activity were detected when activities against CA-MRSA and HA-MRSA were compared...
Antimicrobial susceptibility and staphylococcal chromosomal cassette mec type in community- and hospital-associated methicillin-resistant Staphylococcus aureusKerry L LaPlante
Anti Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, USA
Pharmacotherapy 27:3-10
Anti Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, USA
Pharmacotherapy 27:3-10
....
A useful clinical approach to community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infectionsB A Cunha
J Hosp Infect 68:271-3
J Hosp Infect 68:271-3
[Stakes, treatment strategies and progression of MRSA nosocomial pneumonia, especially pneumonia due to mechanical ventilation]R G Wunderink
Methodist Healthcare, University of Tennessee, Memphis, USA
Presse Med 33:2S5-9
Methodist Healthcare, University of Tennessee, Memphis, USA
Presse Med 33:2S5-9
..BETWEEN EFFICACY AND TOLERANCE: The increase in the MIC of vancomycin in the serum and the lungs during acute MRSA acquired under mechanical ventilation may provoke problems in tolerance, notably renal...
Vancomycin intermediate and resistant Staphylococcus aureus. What the nephrologist needs to knowL Clifford McDonald
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
Nephrol News Issues 18:63-4, 66-7, 71-2 passim
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
Nephrol News Issues 18:63-4, 66-7, 71-2 passim
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[The Dutch MRSA policy should be retained]B J M Vlaminckx
Universitair Medisch Centrum Utrecht
Ned Tijdschr Geneeskd 150:1884
Universitair Medisch Centrum Utrecht
Ned Tijdschr Geneeskd 150:1884
..In addition, widespread use of vancomycin for treating MRSA infections encourages the spread and development of vancomycin-resistant micro-organisms...
[Nosocomial methicillin-resistant staphylococci that remain sensitive to non-beta lactam antibiotics]Roberto Manfredi
Recenti Prog Med 94:344
Recenti Prog Med 94:344
Isolation in Brazil of nosocomial Staphylococcus aureus with reduced susceptibility to vancomycinG A Oliveira
Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil
Infect Control Hosp Epidemiol 22:443-8
Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil
Infect Control Hosp Epidemiol 22:443-8
..This alerts us to the possibility that VRSA may be capable of nosocomial transfer if adequate hospital infection control measures are not taken...
Differential growth of epidemic methicillin-resistant Staphylococcus aureus in vancomycinI Alshami
Department of Medical Microbiology, Clinical Sciences Building 1, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK
Br J Biomed Sci 62:109-13
Department of Medical Microbiology, Clinical Sciences Building 1, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK
Br J Biomed Sci 62:109-13
..EMRSAs 1A, 2A and 15A became more resistant to methicillin, and EMRSAs 8A, 11A and 12A became less resistant to methicillin. These results suggest that more than one mechanism is responsible for this phenomenon...
Frequency of mecA gene and borderline oxacillin resistant Staphylococcus aureus in nosocomial acquired methicillin resistance Staphylococcus aureus infectionsF Khorvash
Isfahan University of Medical Sciences, Hezar Jerib Street, Isfahan, Iran
Pak J Biol Sci 11:1282-5
Isfahan University of Medical Sciences, Hezar Jerib Street, Isfahan, Iran
Pak J Biol Sci 11:1282-5
..in our hospital, vancomycin should be reserved only for life threatening infections due to these organisms. Thus MRSA typing should be done to choose appropriate antibiotic for optimal treatment of MRSA infections...
Comparative in vitro activity of linezolid and five other antimicrobials against nosocomial isolates of methicillin-resistant Staphylococcus aureus, methicillin-resistant Staphylococcus epidermidis and vancomycin-resistant Enterococcus faeciumS Metallidis
1st Internal Medicine Department, Infectious Diseases Division, AHEPA University Hospital, Thessaloniki, Greece
J Chemother 15:442-8
1st Internal Medicine Department, Infectious Diseases Division, AHEPA University Hospital, Thessaloniki, Greece
J Chemother 15:442-8
..faecium had MIC range 0.5-1.5, MIC50 = 1, MIC90 = 1. Linezolid is the first of a novel antimicrobial class, the oxazolidinones, which is a promising treatment for serious Gram-positive infections, including multiresistant strains...
Health care-associated endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycinChia Yu Chi
Division of Clinical Research, National Health Research Institutes, Tainan, Taiwan
J Clin Microbiol 46:810-3
Division of Clinical Research, National Health Research Institutes, Tainan, Taiwan
J Clin Microbiol 46:810-3
..We report the successful treatment of a pediatric patient with SARV IE and characterization of the infecting strain. The MIC of vancomycin rose from 1.5 to 2 microg/ml, and the SARV was confirmed by population analysis...
Staphylococcus aureus bloodstream infections: risk factors, outcomes, and the influence of methicillin resistance in Calgary, Canada, 2000-2006Kevin B Laupland
Department of Medicine, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
J Infect Dis 198:336-43
Department of Medicine, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
J Infect Dis 198:336-43
..aureus bacteremia did not significantly change during the study. CONCLUSIONS: Although the overall influence of S. aureus bacteremia has not significantly changed, MRSA has emerged as an important etiology in our region...
Staphylococcus aureus bacteraemia in children: a 5-year retrospective reviewB A Suryati
Department of Immunology and Infectious Diseases, Children's Hospital at Westmead, Sydney, New South Wales, Australia
J Paediatr Child Health 38:290-4
Department of Immunology and Infectious Diseases, Children's Hospital at Westmead, Sydney, New South Wales, Australia
J Paediatr Child Health 38:290-4
..4%) was significantly lower than the published literature relating to adults (11-32%). CONCLUSION: The present study highlights the differences between S. aureus bacteraemia in adults and children...
Staphylococcus aureus bacteraemia in children and neonates: a 10 year retrospective reviewSarah Denniston
Department of Paediatrics, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B4 5SS, United Kingdom
J Infect 53:387-93
Department of Paediatrics, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B4 5SS, United Kingdom
J Infect 53:387-93
..Most SA in blood cultures are not due to contamination. Prospective studies are needed to determine appropriate investigation and treatment...
Cost of the meticillin-resistant Staphylococcus aureus search and destroy policy in a Dutch university hospitalE Nulens
Medical Microbiology, Algemeen Ziekenhuis Sint Jan, Brugge, Belgium
J Hosp Infect 68:301-7
Medical Microbiology, Algemeen Ziekenhuis Sint Jan, Brugge, Belgium
J Hosp Infect 68:301-7
..At an MRSA prevalence of <or=8% the search and destroy policy remains cost-effective. From an economic point of view, the search and destroy policy is the best alternative at maintaining an endemic MRSA level at <1%...
Methicillin-resistant Staphylococcus aureus bacteraemia in neonatal intensive care units: an analysis of 90 episodesY Y Chuang
Division of Paediatric Infectious Diseases, Chang Gung Children's Hospital, Chang Gung University, Taoyuan, Taiwan
Acta Paediatr 93:786-90
Division of Paediatric Infectious Diseases, Chang Gung Children's Hospital, Chang Gung University, Taoyuan, Taiwan
Acta Paediatr 93:786-90
..In uncomplicated MRSA bacteraemia, treatment with vancomycin for < or = 14 d seems to be adequate...
Vancomycin therapy and the progression of methicillin-resistant Staphylococcus aureus vertebral osteomyelitisMichael S Gelfand
Methodist University Hospital of Memphis, Memphis, TN, USA
South Med J 97:593-7
Methodist University Hospital of Memphis, Memphis, TN, USA
South Med J 97:593-7
..A review of the literature and possible therapeutic alternatives are also discussed...
Pneumonia caused by methicillin-resistant Staphylococcus aureusEthan Rubinstein
University of Manitoba, Winnipeg, Canada
Clin Infect Dis 46:S378-85
University of Manitoba, Winnipeg, Canada
Clin Infect Dis 46:S378-85
A recent increase in staphylococcal infections caused by methicillin-resistant Staphylococcus aureus (MRSA), combined with frequent, prolonged ventilatory support of an aging, often chronically ill population, has resulted in a large ..
[Staphylococcus aureus sepsis in hospitalized non neutropenic patients: retrospective clinical and microbiological analysis]Marco Falcone
Dipartimento di Medicina Clinica, Divisione di Clinica Medica III, Università degli Studi La Sapienza di Roma
Ann Ital Med Int 17:166-72
Dipartimento di Medicina Clinica, Divisione di Clinica Medica III, Università degli Studi La Sapienza di Roma
Ann Ital Med Int 17:166-72
..05) were confirmed as associated with a complicated outcome. SAS in non neutropenic patients is associated with significant morbidity consequent to a high rate of metastatic infectious disease and with a considerable related mortality...
Infective endocarditis caused by USA300 methicillin-resistant Staphylococcus aureus (MRSA)N Z Haque
Henry Ford Health System, Detroit, MI, USA
Int J Antimicrob Agents 30:72-7
Henry Ford Health System, Detroit, MI, USA
Int J Antimicrob Agents 30:72-7
..As USA300 strains of MRSA continue to increase in prevalence, clinicians must be aware of the increasing spectrum of illness in considering management and prevention strategies...
Staphylococcus aureus septicemia in non-neutropenic adult patients hospitalized in internal medicine unitsF Gallucci
Department of Internal Medicine, Cardarelli Hospital, Napoli, Italy
Rocz Akad Med Bialymst 50:216-9
Department of Internal Medicine, Cardarelli Hospital, Napoli, Italy
Rocz Akad Med Bialymst 50:216-9
..8% (7 patients). CONCLUSIONS: SAS in non-neutropenic patients observed in Internal Medicine Units are associated with significant morbidity and mortality, closer to that reported for neutropenic illnesses...
Community-acquired methicillin-resistant Staphylococcus aureus in Madrid, Spain: transcontinental importation and polyclonal emergence of Panton-Valentine leukocidin-positive isolatesEmilia Cercenado
Servicio de MicrobiologÃa, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Diagn Microbiol Infect Dis 61:143-9
Servicio de MicrobiologÃa, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Diagn Microbiol Infect Dis 61:143-9
..Nine patients were from South America. Our results indicate the transcontinental importation and recent emergence in Spain of PVL-positive CA-MRSA strains belonging to 3 distinct lineages, including 1 predominant (ST8-SCCmec IVc)...
Epidemiology of community-acquired Staphylococcus aureus bacteremiaChih-Yu Chi
Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, and National Yang-Ming University, Taipei, Taiwan, ROC
J Microbiol Immunol Infect 37:16-23
Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, and National Yang-Ming University, Taipei, Taiwan, ROC
J Microbiol Immunol Infect 37:16-23
..Early empiric therapy with glycopeptides in these patients may reduce morbidity and mortality...
Epidemiology and outcomes of community-associated methicillin-resistant Staphylococcus aureus infectionS L Davis
Henry Ford Hospital, Detroit, MI, USA
J Clin Microbiol 45:1705-11
Henry Ford Hospital, Detroit, MI, USA
J Clin Microbiol 45:1705-11
..7 to 6.9). In the community setting, the molecular characteristics of the S. aureus strains were heterogeneous. CA-MRSA infections were associated with a more adverse impact on outcome than CA-MSSA infections...
Severe Staphylococcal sepsis in adolescents in the era of community-acquired methicillin-resistant Staphylococcus aureusBlanca E Gonzalez
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
Pediatrics 115:642-8
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA
Pediatrics 115:642-8
OBJECTIVE: More than 70% of the community-acquired (CA) staphylococcal infections treated at Texas Children's Hospital are caused by methicillin-resistant Staphylococcus aureus (MRSA)...
Adult methicillin-resistant Staphylococcus aureus bacteremia in Taiwan: clinical significance of non-multi-resistant antibiogram and Panton-Valentine leukocidin geneJiun Ling Wang
Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan
Diagn Microbiol Infect Dis 59:365-71
Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan
Diagn Microbiol Infect Dis 59:365-71
..Most PVL-positive MRSA isolates belonged to SCCmec V. PVL-positive CA-MRSA isolates could cause more deep-seated infections in patients presented with non-multi-resistant MRSA bacteremia...
Community-onset methicillin-resistant Staphylococcus aureus bacteremia in Northern AustraliaRonan J Murray
Department of Microbiology and Infectious Diseases, Royal Perth Hospital, G P O Box X2213, Perth, Western Australia 6847, Australia
Int J Infect Dis 8:275-83
Department of Microbiology and Infectious Diseases, Royal Perth Hospital, G P O Box X2213, Perth, Western Australia 6847, Australia
Int J Infect Dis 8:275-83
..CONCLUSION: The increasing incidence of COMRSAB in our region has resulted in the addition of vancomycin to standard empiric therapy in certain patients with suspected S. aureus bacteremia acquired in the community...
An analysis of a community-acquired pathogen in a Kentucky community: methicillin-resistant Staphylococcus aureusForest W Arnold
University of Louisville School of Medicine, KY 40292, USA
J Ky Med Assoc 103:206-10
University of Louisville School of Medicine, KY 40292, USA
J Ky Med Assoc 103:206-10
..After incision and drainage, a review of the antimicrobial sensitivities indicates that oral treatment may be adequate for a selection of cases...
Update on emerging infections: news from the Centers for Disease Control and PreventionGregory J Moran
Department of Emergency Medicine, Olive View-UCLA Medical Center, Sylmar, CA, USA
Ann Emerg Med 41:148-51
Department of Emergency Medicine, Olive View-UCLA Medical Center, Sylmar, CA, USA
Ann Emerg Med 41:148-51
Activities of clindamycin, daptomycin, doxycycline, linezolid, trimethoprim-sulfamethoxazole, and vancomycin against community-associated methicillin-resistant Staphylococcus aureus with inducible clindamycin resistance in murine thigh infection and in viKerry L LaPlante
Anti Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, USA
Antimicrob Agents Chemother 52:2156-62
Anti Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, USA
Antimicrob Agents Chemother 52:2156-62
..At present, there are several alternatives that appear promising for treating clindamycin resistance-inducible strains of CA-MRSA...
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