pasteurellaceae infections


Summary: Infections with bacteria of the family PASTEURELLACEAE.

Top Publications

  1. Guenther S, Schierack P, Grobbel M, Lübke Becker A, Wieler L, Ewers C. Real-time PCR assay for the detection of species of the genus Mannheimia. J Microbiol Methods. 2008;75:75-80 pubmed publisher
    ..We assume that the assay could become useful for fast laboratory diagnostic assessment particularly of respiratory infections caused by Mannheimia in animals...
  2. Díaz Aparicio E, Tenorio Gutiérrez V, Arellano Reynoso B, Enríquez Verdugo I, Aguilar Romero F. Pathogenicity of different strains of Histophilus somni in the experimental induction of ovine epididymitis. Can J Vet Res. 2009;73:157-60 pubmed
  3. Delis G, Koutsoviti Papadopoulou M, Siarkou V, Kounenis G, Batzias G. Pharmacodynamics of amoxicillin against Mannheimia haemolytica and Pasteurella multocida and pharmacokinetic/pharmacodynamic (PK/PD) correlation in sheep. Res Vet Sci. 2010;89:418-25 pubmed publisher
    ..1 ?g/mL. Intramuscular administration could be safely considered effective against both "deep" and "shallow" infections when the MICs of the targeted pathogens are lower than 1 ?g/mL...
  4. Jaramillo Arango C, Hernandez Castro R, Suárez Güemes F, Martínez Maya J, Aguilar Romero F, Jaramillo Meza L, et al. Characterisation of Mannheimia spp. strains isolated from bovine nasal exudate and factors associated to isolates, in dairy farms in the Central Valley of Mexico. Res Vet Sci. 2008;84:7-13 pubmed
    ..Bovines younger than one year of age and those with disease were the groups with the highest frequency of M. haemolytica and Mannheimia glucosida isolates...
  5. Geertsema R, Zekarias B, La Franco Scheuch L, Worby C, Russo R, Gershwin L, et al. IbpA DR2 subunit immunization protects calves against Histophilus somni pneumonia. Vaccine. 2011;29:4805-12 pubmed publisher
    ..Therefore, IbpA DR2 appears to be an important protective antigen of H. somni. The study shows, for the first time, that immunization with a purified Fic protein protects against disease in a natural host. ..
  6. Spagnoli S, Reilly T, Calcutt M, Fales W, Kim D. Subcutaneous botryomycosis due to Bibersteinia trehalosi in a Texas Longhorn steer. Vet Pathol. 2012;49:775-8 pubmed publisher
    ..This case of botryomycosis is unique for its association with Bibersteinia trehalosi. ..
  7. Jorth P, Trivedi U, Rumbaugh K, Whiteley M. Probing bacterial metabolism during infection using high-resolution transcriptomics. J Bacteriol. 2013;195:4991-8 pubmed publisher
    ..These results not only provide a high-resolution genomic analysis of a bacterial pathogen during in vivo growth but also provide new insight into metabolic pathways required for A. actinomycetemcomitans in vivo fitness. ..
  8. Weiser G, Miller D, Drew M, Rhyan J, Ward A. Variation in Pasteurella (Bibersteinia) and Mannheimia spp. following transport and antibiotic treatment in free-ranging and captive Rocky Mountain bighorn sheep (Ovis canadensis canadensis). J Zoo Wildl Med. 2009;40:117-25 pubmed
  9. Fragkou I, Gougoulis D, Billinis C, Mavrogianni V, Bushnell M, Cripps P, et al. Transmission of Mannheimia haemolytica from the tonsils of lambs to the teat of ewes during sucking. Vet Microbiol. 2011;148:66-74 pubmed publisher
    ..9. Results provide clear evidence that suckling by lambs can lead to transmission of M. haemolytica into the teats of the ewes; the bacteria have the potential to cause mastitis if circumstances are favourable. ..

More Information

Publications103 found, 100 shown here

  1. Burciaga Robles L, Step D, Krehbiel C, Holland B, Richards C, Montelongo M, et al. Effects of exposure to calves persistently infected with bovine viral diarrhea virus type 1b and subsequent infection with Mannheima haemolytica on clinical signs and immune variables: model for bovine respiratory disease via viral and bacterial inte. J Anim Sci. 2010;88:2166-78 pubmed publisher
    ..haemolytica. Understanding the physiological changes in morbid animals will lead to improved strategies for decreasing severity and economic losses associated with BRD. ..
  2. Christensen H, Bisgaard M, Larsen J, Olsen J. PCR-detection of Hemophilus paragallinarum, Hemophilus somnus, Mannheimia (Pasteurella) hemolytica, Mannheimia spp., Pasteurella trehalosi, and Pasteurella multocida. Methods Mol Biol. 2003;216:257-74 pubmed
  3. Petersen A, Christensen H, Kodjo A, Weiser G, Bisgaard M. Development of a multilocus sequence typing (MLST) scheme for Mannheimia haemolytica and assessment of the population structure of isolates obtained from cattle and sheep. Infect Genet Evol. 2009;9:626-32 pubmed publisher
    ..In conclusion, an unambiguous typing scheme is presented for M. haemolytica and results obtained confirm previous observations of a clonal population of the organism. ..
  4. Dassanayake R, Call D, Sawant A, Casavant N, Weiser G, Knowles D, et al. Bibersteinia trehalosi inhibits the growth of Mannheimia haemolytica by a proximity-dependent mechanism. Appl Environ Microbiol. 2010;76:1008-13 pubmed publisher
    ..These observations demonstrate that B. trehalosi can both outgrow and inhibit M. haemolytica growth with the latter related to a proximity- or contact-dependent mechanism...
  5. Moustacas V, Silva T, Costa L, Xavier M, Carvalho C, Costa E, et al. Species-specific multiplex PCR for the diagnosis of Brucella ovis, Actinobacillus seminis, and Histophilus somni infection in rams. BMC Vet Res. 2013;9:51 pubmed publisher
  6. Bager R, Persson G, Nesta B, Soriani M, Serino L, Jeppsson M, et al. Outer membrane vesicles reflect environmental cues in Gallibacterium anatis. Vet Microbiol. 2013;167:565-72 pubmed publisher
    ..anatis produce OMVs in vitro and the OMV protein profile suggests that the production is an important and well-regulated ability employed by the bacteria, which may be used for vaccine production purposes. ..
  7. Sandal I, Shao J, Annadata S, Apicella M, Boye M, Jensen T, et al. Histophilus somni biofilm formation in cardiopulmonary tissue of the bovine host following respiratory challenge. Microbes Infect. 2009;11:254-63 pubmed publisher
  8. Bojesen A, Nielsen S, Bisgaard M. Prevalence and transmission of haemolytic Gallibacterium species in chicken production systems with different biosecurity levels. Avian Pathol. 2003;32:503-10 pubmed
    ..In general, flock infections resembled an 'all or none' type of colonization as practically all of the chickens in infected flocks sampled positive. There was no evidence of vertical transmission of Gallibacterium...
  9. Mavrogianni V, Cripps P, Papaioannou N, Taitzoglou I, Fthenakis G. Teat disorders predispose ewes to clinical mastitis after challenge with Mannheimia haemolytica. Vet Res. 2006;37:89-105 pubmed
    ..We postulate that teat lesions can be predisposing factor to mastitis, by adversely affecting defences and speeding the process of infection and making it more severe...
  10. Hansen M, Bertelsen M, Delaney M, Fravel V, Gulland F, Bojesen A. Otariodibacter oris and Bisgaardia genomospecies 1 isolated from infections in pinnipeds. J Wildl Dis. 2013;49:661-5 pubmed publisher
    ..Likewise, the isolation of Bisgaardia genomospecies 1 in pure culture from an abscess in a harbor seal implies causality. ..
  11. Griffin D. Bovine pasteurellosis and other bacterial infections of the respiratory tract. Vet Clin North Am Food Anim Pract. 2010;26:57-71, table of contents pubmed publisher
  12. Wu J, Wu Y, Shien J, Hsu Y, Chen C, Shieh H, et al. Recombinant proteins containing the hypervariable region of the haemagglutinin protect chickens against challenge with Avibacterium paragallinarum. Vaccine. 2011;29:660-7 pubmed publisher
    ..paragallinarum of the homologous serovar. These results suggest that recombinant proteins containing the hypervariable region may be useful antigens for use in the development of a vaccine against A. paragallinarum. ..
  13. Davis A, Crum L, Corbeil L, Hildebrand M. Expression of Histophilus somni IbpA DR2 protective antigen in the diatom Thalassiosira pseudonana. Appl Microbiol Biotechnol. 2017;101:5313-5324 pubmed publisher
    ..Mice exposed to 5 ?g of diatom-expressed DR2 in whole or sonicated cells (without protein purification) exhibited a modest immune response without the addition of adjuvant. ..
  14. Sisay T, Zerihun A. Diversity of Mannheimia haemolytica and pasteurella trehalosi serotypes from apparently healthy sheep and abattoir specimens in the highlands of Wollo, North East Ethiopia. Vet Res Commun. 2003;27:3-14 pubmed
    ..Multiple serotypes were common in all types of samples. The importance of including in vaccines the most prevalent serotypes involved in the pneumonia of sheep in the area is discussed. ..
  15. St Michael F, Cairns C, Filion A, Neelamegan D, Lacelle S, Cox A. Investigating the candidacy of lipopolysaccharide-based glycoconjugates as vaccines to combat Mannheimia haemolytica. Glycoconj J. 2011;28:397-410 pubmed publisher
  16. Karched M, Furgang D, Planet P, DeSalle R, Fine D. Genome sequence of Aggregatibacter actinomycetemcomitans RHAA1, isolated from a rhesus macaque, an Old World primate. J Bacteriol. 2012;194:1275-6 pubmed publisher
    ..Aggregatibacter actinomycetemcomitans is implicated in localized aggressive periodontitis. We report the first genome sequence of an A. actinomycetemcomitans strain isolated from an Old World primate...
  17. Blum S, Freed M, Zukin N, Shwimmer A, Weissblit L, Khatib N, et al. Bovine subclinical mastitis caused by Mannheimia granulomatis. J Vet Diagn Invest. 2010;22:995-7 pubmed
    ..Mannheimia granulomatis was isolated for 10 months from the milk of a cow with elevated somatic cell counts. The infection was self-limiting. Phenotypic and molecular characteristics of the isolate were determined...
  18. Fine D, Furgang D, McKiernan M, Rubin M. Can salivary activity predict periodontal breakdown in A. actinomycetemcomitans infected adolescents?. Arch Oral Biol. 2013;58:611-20 pubmed publisher
    ..A salivary activity profile can distinguish between subjects who are Aa-positive and remain healthy from those who develop LAP. ..
  19. Hanatani T, Suzuki J, Ogawa M, Aoyama N, Kobayashi N, Hirata Y, et al. The periodontal pathogen Aggregatibacter actinomycetemcomitans deteriorates ventricular remodeling after myocardial infarction in mice. Int Heart J. 2012;53:253-6 pubmed
    ..a.-negative MI mice. The injection of A.a. into the mice without MI did not affect their hearts. We concluded that a periodontal pathogen infection might deteriorate ventricular remodeling after MI through inflammatory cell infiltration. ..
  20. Bager R, Nesta B, Pors S, Soriani M, Serino L, Boyce J, et al. The fimbrial protein FlfA from Gallibacterium anatis is a virulence factor and vaccine candidate. Infect Immun. 2013;81:1964-73 pubmed publisher
    ..anatis strains, suggesting the potential of FlfA as a serotype-independent vaccine candidate This is the first study describing a fimbrial subunit protein of G. anatis with a clear potential as a vaccine antigen. ..
  21. Leite F, Atapattu D, Kuckleburg C, Schultz R, Czuprynski C. Incubation of bovine PMNs with conditioned medium from BHV-1 infected peripheral blood mononuclear cells increases their susceptibility to Mannheimia haemolytica leukotoxin. Vet Immunol Immunopathol. 2005;103:187-93 pubmed
  22. Andrade G, Ladeira S, Battlehner C, Saldiva P, Caldini E. Molecular and ultrastructural studies of the fibrotic lesions of bovine focal proliferative fibrogranulomatous panniculitis (Lechiguana). Vet Res Commun. 2008;32:65-74 pubmed
    ..The results strongly suggest the involvement of a myofibroblast-like cell population that expresses mRNA for type I collagen and is probably associated with the increase of collagen deposition...
  23. Berry B, Krehbiel C, Confer A, Gill D, Smith R, Montelongo M. Effects of dietary energy and starch concentrations for newly received feedlot calves: I. Growth performance and health. J Anim Sci. 2004;82:837-44 pubmed
    ..Although animal performance was not influenced, the present data suggest that feeding the high-energy diet decreased the percentage of P. multocida and H. somnus pathogens in calves that received one or more antimicrobial treatments...
  24. Fett T, Zecchinon L, Vanden Bergh P, Desmecht D. Mannheimia haemolytica leukotoxin-induced cytolysis of caprine (Capra hircus) leukocytes is mediated by the CD18 subunit of beta2-integrins. Microb Pathog. 2008;45:337-42 pubmed publisher
    ..Taken together, these results indicate that CD18 on caprine leukocytes serves as a receptor for Lkt. ..
  25. Repeke C, Ferreira S, Vieira A, Silveira E, Avila Campos M, Da Silva J, et al. Dose-response met-RANTES treatment of experimental periodontitis: a narrow edge between the disease severity attenuation and infection control. PLoS ONE. 2011;6:e22526 pubmed publisher
  26. Blackall P, O Dell R, Stephens C. Minimal inhibitory concentration of tilmicosin against isolates of Histophilus somni from Australian cattle. Aust Vet J. 2007;85:503-4 pubmed
  27. Tan T, Ng L, Eng L. Five clinical cases of Necropsobacter rosorum bacteremia. J Clin Microbiol. 2013;51:1337-40 pubmed publisher
    ..N. rosorum is consistently misidentified by commercial identification systems, which may delay recognition of this organism as a human pathogen...
  28. Miller M, Hause B, Killion H, Fox K, Edwards W, Wolfe L. Phylogenetic and epidemiologic relationships among Pasteurellaceae from Colorado bighorn sheep herds. J Wildl Dis. 2013;49:653-60 pubmed publisher
    ..g., M. haemolytica sensu stricto and lktA-positive B. trehalosi) and other select pathogens may be most informative for investigating and managing bighorn respiratory disease. ..
  29. Rose Dye T, Burciaga Robles L, Krehbiel C, Step D, Fulton R, Confer A, et al. Rumen temperature change monitored with remote rumen temperature boluses after challenges with bovine viral diarrhea virus and Mannheimia haemolytica. J Anim Sci. 2011;89:1193-200 pubmed publisher
    ..89). Rumen temperature boluses appear to have potential as a tool for detecting temperature changes associated with adverse health events such as exposure to bovine respiratory disease and BVDV...
  30. Dyer N, Ward A, Weiser G, White D. Seasonal incidence and antibiotic susceptibility patterns of Pasteurellaceae isolated from American bison (Bison bison). Can J Vet Res. 2001;65:7-14 pubmed
    ..The most common resistance pattern observed was to neomycin and spectinomycin (73/147) (49%). ..
  31. Jones K, Thornton J, Zhang Y, Mauel M. A 5-year retrospective report of Gallibacterium anatis and Pasteurella multocida isolates from chickens in Mississippi. Poult Sci. 2013;92:3166-71 pubmed publisher
    ..multocida for fear that the culprit may actually be the more antimicrobial-resistant G. anatis. ..
  32. Inkaya A, Maçin S, Bozkurt G, Gocmen R, Akyon Y, Unal S. Aggregatibacter aphrophilus misidentified as Brucella spp. in an immunocompetent patient with brain abscess. J Pak Med Assoc. 2016;66:1032-4 pubmed
    ..Right to left shunt through the pulmonary arteriovenous malformation was speculated to be the underlying cause for the brain abscess. The patient was treated successfully with ampicillin-sulbactam after failing ceftriaxone treatment. ..
  33. Fernández Varón E, Cárceles García C, Serrano Rodríguez J, Cárceles Rodríguez C. Pharmacokinetics (PK), pharmacodynamics (PD), and PK-PD integration of ceftiofur after a single intravenous, subcutaneous and subcutaneous-LA administration in lactating goats. BMC Vet Res. 2016;12:232 pubmed
    ..Thus, this drug could be effective in treating infectious diseases of goats caused by M. haemolytica at a dose of 6 mg/kg with the SC-LA formulation. ..
  34. Greko C, Finn M, Ohagen P, Franklin A, Bengtsson B. A tissue cage model in calves for studies on pharmacokinetic/pharmacodynamic interactions of antimicrobials. Int J Antimicrob Agents. 2003;22:429-38 pubmed
    ..If drug dosages in relation to the MIC of strains used for infection are optimised, the model offers an interesting alternative to explore relevant factors for drug dosage optimisation. ..
  35. Lawrence P, Dassanayake R. Ovis aries CR4 is involved in Mannheimia haemolytica leukotoxin-induced cytotoxicity. Vet Immunol Immunopathol. 2010;135:266-74 pubmed publisher
    ..haemolytica Lkt and mediate concentration-dependent lysis of host cells, thus, confirming their role in M. haemolytica pathogenesis. This is a critical step in understanding host innate immunity and the management of pneumonia in sheep...
  36. Kuhnert P, Korczak B, Falsen E, Straub R, Hoops A, Boerlin P, et al. Nicoletella semolina gen. nov., sp. nov., a new member of Pasteurellaceae isolated from horses with airway disease. J Clin Microbiol. 2004;42:5542-8 pubmed
    ..6%), and infB (99.7%) sequences exist within the species, indicating that N. semolina isolates not only are phenotypically homogeneous but also are genetically homogeneous. The type strain of N. semolina is CCUG43639(T) (DSM16380(T))...
  37. Ismail M, El Kattan Y. Comparative pharmacokinetics of marbofloxacin in healthy and Mannheimia haemolytica infected calves. Res Vet Sci. 2007;82:398-404 pubmed
    ..haemolytica, which can be expected to optimize the clinical efficacy and minimize the development of resistance...
  38. Benrachadi L, Bouziane A, Azziman Z, Bouziane Ouartini F, Ennibi O. Screening for periodontopathogenic bacteria in severe chronic periodontitis in a Moroccan population. Med Mal Infect. 2012;42:599-602 pubmed publisher
  39. Katsuda K, Kohmoto M, Kawashima K, Tsunemitsu H, Tsuboi T, Eguchi M. Molecular typing of Mannheimia (Pasteurella) haemolytica serotype A1 isolates from cattle in Japan. Epidemiol Infect. 2003;131:939-46 pubmed
    ..These results indicate that isolates of M. haemolytica A1 strain with various molecular profiles have already spread in Japan and may have caused sporadic infections...
  40. Ozawa M, Asai T, Sameshima T. Mutations in GyrA and ParC in fluoroquinolone-resistant Mannheimia haemolytica isolates from cattle in Japan. J Vet Med Sci. 2009;71:493-4 pubmed
    ..Three mutations in the QRDRs of GyrA were found in the NA-resistant isolates: S83Y in two isolates, S83F in two isolates and D87G in one isolate...
  41. Chien J, Lin C, Chen Y, Lay C, Wang C, Tsai C. Epidural abscess caused by Haemophilus aphrophilus misidentified as Pasteurella species. Intern Med. 2009;48:853-8 pubmed
    ..He was successfully treated with adequate antibiotics and surgery. The clinical features of sixteen previously reported cases of spinal infection caused by H. aphrophilus are reviewed...
  42. Inamoto I, Lo R. Identification of putative two-component regulatory systems in the bovine pathogen Mannheimia haemolytica A1, and preliminary characterization of the NarQ/P system. FEMS Microbiol Lett. 2010;311:27-35 pubmed publisher
    ..The expression of the leukotoxin gene was also altered in the narP mutant as shown by Western immunoblot analysis and reverse transcription-PCR...
  43. D Amours G, Ward T, Mulvey M, Read R, Morck D. Genetic diversity and tetracycline resistance genes of Histophilus somni. Vet Microbiol. 2011;150:362-72 pubmed publisher
  44. Kristensen B, Frees D, Bojesen A. Expression and secretion of the RTX-toxin GtxA among members of the genus Gallibacterium. Vet Microbiol. 2011;153:116-23 pubmed publisher
    ..In conclusion, we have shown that differences in haemolytic properties among strains of Gallibacterium may be explained by both genotypic differences and by differential expression...
  45. Subramaniam R, Shanthalingam S, Bavananthasivam J, Kugadas A, Potter K, Foreyt W, et al. A multivalent Mannheimia-Bibersteinia vaccine protects bighorn sheep against Mannheimia haemolytica challenge. Clin Vaccine Immunol. 2011;18:1689-94 pubmed publisher
    ..haemolytica challenge which is likely to reduce the BHS population decline due to pneumonia...
  46. Walsh D, Wolfe L, Vieira M, Miller M. Detection probability and Pasteurellaceae surveillance in bighorn sheep. J Wildl Dis. 2012;48:593-602 pubmed
    ..Detection probability impacts the results reported from bacterial cultures for Pasteurellaceae in bighorn sheep, and confounding effects of the detection process should be addressed to improve the rigor of surveillance...
  47. Izawa A, Ishihara Y, Mizutani H, Kobayashi S, Goto H, Okabe E, et al. Inflammatory bone loss in experimental periodontitis induced by Aggregatibacter actinomycetemcomitans in interleukin-1 receptor antagonist knockout mice. Infect Immun. 2014;82:1904-13 pubmed publisher
    ..In short, these data suggest that IL-1Ra may serve as a potential therapeutic drug for periodontal disease. ..
  48. Welsh R, Dye L, Payton M, Confer A. Isolation and antimicrobial susceptibilities of bacterial pathogens from bovine pneumonia: 1994--2002. J Vet Diagn Invest. 2004;16:426-31 pubmed
    ..0001), and trimethoprim/sulfamethoxazole (P = 0.0003). Antimicrobial susceptibilities for H. somni were variable for spectinomycin and sulfachloropyridizine, whereas susceptibilities to other antibiotics remained consistently high...
  49. Noro T, Oishi E, Kaneshige T, Yaguchi K, Amimoto K, Shimizu M. Identification and characterization of haemagglutinin epitopes of Avibacterium paragallinarum serovar C. Vet Microbiol. 2008;131:406-13 pubmed publisher
    ..5 is a practical candidate protein to develop a new vaccine against avian infectious coryza caused by Av. paragallinarum serovar C...
  50. Hyvärinen K, Tuomainen A, Laitinen S, Bykov I, Törmäkangas L, Lindros K, et al. Chlamydial and periodontal pathogens induce hepatic inflammation and fatty acid imbalance in apolipoprotein E-deficient mice. Infect Immun. 2009;77:3442-9 pubmed publisher
    ..Our results indicate that proatherogenic pathogens infect the liver, causing proinflammatory alterations and lipid disturbances. This infection may maintain chronic systemic inflammation attributable to atherogenesis...
  51. Krol J, Bania J, Florek M, Pliszczak Król A, Staroniewicz Z. Polymerase chain reaction-based identification of clinically relevant Pasteurellaceae isolated from cats and dogs in Poland. J Vet Diagn Invest. 2011;23:532-7 pubmed publisher
    ..The PCR assays were shown to be species specific, providing a valuable supplement to phenotypic identification of species within this group of bacteria...
  52. Lo K, Kimball R, Lehmann J, Gershwin L, Worby C, Corbeil L. Antibody responses of calves to Histophilus somni recombinant IbpA subunits. Comp Immunol Microbiol Infect Dis. 2012;35:453-9 pubmed publisher
    ..somni, vaccinated calves had slight anamnestic responses to IbpA3 and IbpA5, but not to IbpA DR2. Since IbpA DR2 is a protective antigen, the data suggest the IbpA DR2 would be a useful addition to H. somni vaccines...
  53. Mombelli A, Cionca N, Almaghlouth A, Décaillet F, Courvoisier D, Giannopoulou C. Are there specific benefits of amoxicillin plus metronidazole in Aggregatibacter actinomycetemcomitans-associated periodontitis? Double-masked, randomized clinical trial of efficacy and safety. J Periodontol. 2013;84:715-24 pubmed publisher
    ..actinomycetemcomitans with moderate to advanced periodontitis benefit specifically from amoxicillin plus metronidazole given as an adjunct to full-mouth scaling and root planing...
  54. Britton A, Zabek E. Bronchopneumonia in two dairy calves associated with Mannheimia species cluster V infection. J Vet Diagn Invest. 2012;24:1043-6 pubmed publisher
    ..Lesions were linked to the presence of leukotoxin A based on phenotypic hemolysis and molecular demonstration of the leukotoxin A gene...
  55. Agnes J, Zekarias B, Shao M, Anderson M, Gershwin L, Corbeil L. Bovine respiratory syncytial virus and Histophilus somni interaction at the alveolar barrier. Infect Immun. 2013;81:2592-7 pubmed publisher
    ..Enhanced breakdown of collagen IV in the basal lamina and of fibrillar collagen I in the adjacent interstitium in the dual infection may facilitate dissemination of H. somni infection...
  56. Wessels J, Wessels M, Thompson L. Histophilus somni myocarditis in cattle in the UK. Vet Rec. 2004;154:608 pubmed
  57. Ramón Rocha M, García González O, Pérez Méndez A, Ibarra Caballero J, Pérez Márquez V, Vaca S, et al. Membrane vesicles released by Avibacterium paragallinarum contain putative virulence factors. FEMS Microbiol Lett. 2006;257:63-8 pubmed
    ..Nucleic acids were also detected inside MVs. Avibacterium paragallinarum releases MVs containing putative virulence factors, which could be important in the pathogenesis of infectious coryza...
  58. Mendoza Espinoza A, Terzolo H, Delgado R, Zavaleta A, Koga Y, Huberman Y. Serotyping of Avibacterium paragallinarum isolates from Peru. Avian Dis. 2009;53:462-5 pubmed
    ..Cross-protection trials are needed to compare the protection conferred by vaccines containing traditional B serovar strains to the protection by experimental vaccines containing variant B serovar isolates from Peru...
  59. Wolfe L, Diamond B, Spraker T, Sirochman M, Walsh D, Machin C, et al. A bighorn sheep die-off in southern Colorado involving a Pasteurellaceae strain that may have originated from syntopic cattle. J Wildl Dis. 2010;46:1262-8 pubmed
    ..Our and others' findings suggest that intimate interactions between wild sheep and cattle should be discouraged as part of a comprehensive approach to health management and conservation of North American wild sheep species...
  60. Miller D, Weiser G, Ward A, Drew M, Chapman P. Domestic sheep (Ovis aries) Pasteurellaceae isolates from diagnostic submissions to the Caine Veterinary Teaching Center (1990-2004). Vet Microbiol. 2011;150:284-8 pubmed publisher
    ..50-1.19). The inference of this study is limited due to the retrospective study design. However, it is the first study that provides an extensive baseline list of biovariants associated with respiratory disease in domestic sheep...
  61. Hansson I, Johansson K, Persson M, Riihimäki M. The clinical significance of Nicoletella semolina in horses with respiratory disorders and a screening of the bacterial flora in the airways of horses. Vet Microbiol. 2013;162:695-9 pubmed publisher
    ..In conclusion, N. semolina is not a primary pathogenic bacterium, as it was isolated at similar frequencies in horses with respiratory disorders and those in the healthy control group...
  62. Höglund Aberg C, Antonoglou G, Haubek D, Kwamin F, Claesson R, Johansson A. Cytolethal distending toxin in isolates of Aggregatibacter actinomycetemcomitans from Ghanaian adolescents and association with serotype and disease progression. PLoS ONE. 2013;8:e65781 pubmed publisher
    ..actinomycetemcomitans collected from an adolescent West African population and to examine the association between the carrier status of A. actinomycetemcomitans and the progression of attachment loss (AL)...
  63. White B, Goehl D, Amrine D, Booker C, Wildman B, Perrett T. Bayesian evaluation of clinical diagnostic test characteristics of visual observations and remote monitoring to diagnose bovine respiratory disease in beef calves. Prev Vet Med. 2016;126:74-80 pubmed publisher
    ..3%) and low (2.6%) prevalence situations. This research illustrates the potential of remote cattle monitoring to augment conventional methods of BRD diagnosis resulting in more accurate identification of diseased cattle. ..
  64. Takeda S, Arashima Y, Kato K, Ogawa M, Kono K, Watanabe K, et al. A case of Pasteurella haemolytica sepsis in a patient with mitral valve disease who developed a splenic abscess. Scand J Infect Dis. 2003;35:764-5 pubmed
    ..We report a patient with sepsis caused by Pasteurella haemolytica, an extremely rare etiologic agent of human infection, who had mitral valve disease and developed a splenic abscess...
  65. Lo R, Sathiamoorthy S, Shewen P. Analysis of in vivo expressed genes in Mannheimia haemolytica A1. FEMS Microbiol Lett. 2006;265:18-25 pubmed
    ..The regulator proteins may be required in higher levels to regulate expression of target genes...
  66. Bojesen A, Larsen J, Pedersen A, Morner T, Mattson R, Bisgaard M. Identification of a novel Mannheimia granulomatis lineage from lesions in roe deer (Capreolus capreolus). J Wildl Dis. 2007;43:345-52 pubmed
    ..granulomatis. The lktA genotype was present in all roe deer isolates based on Southern blot analysis, whereas the corresponding beta-hemolytic phenotype was absent in one of these isolates...
  67. Zhao Q, Sun Y, Zhang X, Kong Y, Xie Z, Zhu Y, et al. Evaluation of two experimental infection models for Avibacterium paragallinarum. Vet Microbiol. 2010;141:68-72 pubmed publisher
    ..Thus, on carrying out animal experiments, the effect of 'in-contact' challenge model is more accurate than the artificial intrasinus-injection-route model...
  68. Chukiatsiri K, Sasipreeyajan J, Neramitmansuk W, Chansiripornchai N. Efficacy of autogenous killed vaccine of Avibacterium paragallinarum. Avian Dis. 2009;53:382-6 pubmed
    ..This is in contrast to the unvaccinated control group, in which facial edema and serous nasal discharge was found, and bacteria could be isolated from all chickens in the group...
  69. Johnson T, Fernández Alarcón C, Bojesen A, Nolan L, Trampel D, Seemann T. Complete genome sequence of Gallibacterium anatis strain UMN179, isolated from a laying hen with peritonitis. J Bacteriol. 2011;193:3676-7 pubmed publisher
    ..Here we report the availability of the first completed G. anatis genome sequence of strain UMN179, isolated from an Iowa laying hen with peritonitis...
  70. Cortelli J, Aquino D, Cortelli S, Roman Torres C, Franco G, Gomez R, et al. Aggregatibacter actinomycetemcomitans serotypes infections and periodontal conditions: a two-way assessment. Eur J Clin Microbiol Infect Dis. 2012;31:1311-8 pubmed publisher
    ..actinomycetemcomitans serotype b. Non-typeable strains were either not detected or were relatively infrequent, and serotypes d and f were not detected in the examined Brazilian population...
  71. Ashigaki N, Suzuki J, Aoyama N, Ogawa M, Watanabe R, Kobayashi N, et al. The periodontal pathogen Aggregatibacter actinomycetemcomitans affects experimental autoimmune myocarditis in mice. Int Heart J. 2013;54:412-6 pubmed
    ..a.-injected EAM group exhibited significantly increased expressions of MMP-9 mRNA compared to the hearts of the mice in the PBS-injected EAM group (P < 0.05). These results show that A.a. aggravated EAM via an enhanced MMP expression...
  72. McGill J, Rusk R, Guerra Maupome M, Briggs R, Sacco R. Bovine Gamma Delta T Cells Contribute to Exacerbated IL-17 Production in Response to Co-Infection with Bovine RSV and Mannheimia haemolytica. PLoS ONE. 2016;11:e0151083 pubmed publisher
    ..Together, our results demonstrate that calves, like humans, mount a robust IL-17 response during RSV infection; and suggest a previously unrecognized role for IL-17 and γδ T cells in the pathogenesis of BRDC. ..
  73. Kawamoto D, Ando Suguimoto E, Bueno Silva B, DiRienzo J, Mayer M. Alteration of Homeostasis in Pre-osteoclasts Induced by Aggregatibacter actinomycetemcomitans CDT. Front Cell Infect Microbiol. 2016;6:33 pubmed publisher
    ..Therefore, the CDT may impair host defense mechanisms in periodontitis. ..
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  75. Gånheim C, Johannisson A, Ohagen P, Persson Waller K. Changes in peripheral blood leucocyte counts and subpopulations after experimental infection with BVDV and/or Mannheimia haemolytica. J Vet Med B Infect Dis Vet Public Health. 2005;52:380-5 pubmed
    ..The drops were most pronounced in the BVDV/Mh group. The numbers of B+ lymphocytes and IL-2R+ cells did not change significantly...
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    ..The findings support previous suggestions that G. anatis biovar haemolytica is associated with infection of the reproductive tract of chickens, making it a likely cause of lowered productivity and an animal welfare concern...
  77. Fragkou I, Dagleish M, Papaioannou N, Cripps P, Boscos C, Ververidis H, et al. The induction of lymphoid follicle-like structures in the ovine teat duct following experimental infection with Mannheimia haemolytica. Vet J. 2010;184:194-200 pubmed publisher
    ..The findings suggest that these organised lymphoid structures are inducible and contribute to the defence of the infected teat when the PMN-macrophage response is overwhelmed...
  78. Zhang T, Kurita Ochiai T, Hashizume T, Du Y, Oguchi S, Yamamoto M. Aggregatibacter actinomycetemcomitans accelerates atherosclerosis with an increase in atherogenic factors in spontaneously hyperlipidemic mice. FEMS Immunol Med Microbiol. 2010;59:143-51 pubmed publisher
    ..Increases in proatherogenic factors may explain the aggravation of atherosclerosis by A. actinomycetemcomitans infection...
  79. Zepeda V, Calderón Apodaca N, Paasch M, Martin P, Paredes D, Ramírez Apolinar S, et al. Histopathologic findings in chickens experimentally infected with Gallibacterium anatis by nasal instillation. Avian Dis. 2010;54:1306-9 pubmed
    ..Because several degrees of severity were established in histopathologic lesions, probable variations in virulence, among the experimental strains, also are discussed...
  80. Omaleki L, Browning G, Allen J, Barber S. Molecular epidemiology of Mannheimia haemolytica and Mannheimia glucosida associated with ovine mastitis. J Vet Diagn Invest. 2012;24:730-4 pubmed publisher
  81. Usui M, Nagai H, Tamura Y. An in vitro method for evaluating endotoxic activity using prostaglandin E(2) induction in bovine peripheral blood. Biologicals. 2013;41:158-61 pubmed publisher
    ..These results may provide a reason for the many report of side effects of H. somni-containing vaccines. The PGE2 detection assay described here could be a valuable method for evaluating the endotoxic activities of vaccines in cows...
  82. Paino A, Ahlstrand T, Nuutila J, Navickaite I, Lahti M, Tuominen H, et al. Identification of a novel bacterial outer membrane interleukin-1?-binding protein from Aggregatibacter actinomycetemcomitans. PLoS ONE. 2013;8:e70509 pubmed publisher
    ..Our findings suggest that A. actinomycetemcomitans expresses an IL-1?-binding surface-exposed lipoprotein that may be part of the bacterial IL-1?-sensing system...
  83. Szenci O, Sassi G, Fodor L, Molnar L, Szelenyi Z, Tibold J, et al. Co-infection with Bovine Herpesvirus 4 and Histophilus somni Significantly Extends the Service Period in Dairy Cattle with Purulent Vaginal Discharge. Reprod Domest Anim. 2016;51:143-9 pubmed publisher
    ..Based on these clinical and comparative data, our results confirm that these two microorganisms together may impair important reproductive parameters which may cause large economic losses to dairy farms...
  84. Berge A, Sischo W, Craigmill A. Antimicrobial susceptibility patterns of respiratory tract pathogens from sheep and goats. J Am Vet Med Assoc. 2006;229:1279-81 pubmed
    ..To determine the antimicrobial susceptibility of common respiratory tract pathogens from sheep and goats...
  85. Bojesen A, Shivaprasad H. Genetic diversity of Gallibacterium isolates from California turkeys. Avian Pathol. 2007;36:227-30 pubmed
    ..Similarly, the same clone was identified from two of the three German flocks. Further investigation of the spread of Gallibacterium between turkey flocks, including infections acquired from chickens or wild birds, should be carried out...
  86. Aulik N, Hellenbrand K, Kisiela D, Czuprynski C. Mannheimia haemolytica leukotoxin binds cyclophilin D on bovine neutrophil mitochondria. Microb Pathog. 2011;50:168-78 pubmed publisher
    ..These data confirm that LKT binds to bovine neutrophil mitochondria, but indicate there are distinctions between neutrophil and BL-3 mitochondria that might reflect differences in cyclophilin D...
  87. Huangfu H, Zhao J, Yang X, Chen L, Chang H, Wang X, et al. Development and preliminary application of a quantitative PCR assay for detecting gtxA-containing Gallibacterium species in chickens. Avian Dis. 2012;56:315-20 pubmed
  88. Guzmán Brambila C, Rojas Mayorquín A, Flores Samaniego B, Ortuño Sahagún D. Two outer membrane lipoproteins from Histophilus somni are immunogenic in rabbits and sheep and induce protection against bacterial challenge in mice. Clin Vaccine Immunol. 2012;19:1826-32 pubmed publisher
    ..somni bacterial challenge...
  89. Klima C, Zaheer R, Briggs R, McAllister T. A multiplex PCR assay for molecular capsular serotyping of Mannheimia haemolytica serotypes 1, 2, and 6. J Microbiol Methods. 2017;139:155-160 pubmed publisher
    ..In addition, the gene targets identified in this study can be used in silico to identify serotype 1, 2, and 6 strains in sequenced M. haemolytica isolates without the need for culture based analysis. ..
  90. Poulsen L, Reinert T, Sand R, Bisgaard M, Christensen H, Olsen J, et al. Occurrence of haemolytic Mannheimia spp. in apparently healthy sheep in Norway. Acta Vet Scand. 2006;48:19 pubmed publisher
    ..The aim of the present study was to evaluate the occurrence of haemolytic Mannheimia species in apparently healthy sheep originating from four sheep flocks in South-Western Norway...
  91. Colles K. Cattle fertility problems and Histophilus somni. Vet Rec. 2007;160:672 pubmed
  92. Dwan L, Thompson H, Taylor D, Philbey A. Laryngeal abscessation due to Mannheimia haemolytica in an alpaca (Vicugna pacos) cria. Vet Rec. 2008;163:124-5 pubmed