fusobacterium infections


Summary: Infections with bacteria of the genus FUSOBACTERIUM.

Top Publications

  1. Epaulard O, Brion J, Stahl J, Colombe B, Maurin M. The changing pattern of Fusobacterium infections in humans: recent experience with Fusobacterium bacteraemia. Clin Microbiol Infect. 2006;12:178-81 pubmed
    ..Only one patient presented with a classic Lemierre's syndrome. These results suggest an opportunistic pattern of modern fusobacterium infections.
  2. Murray S, Lieberman J. Fusobacterium osteomyelitis in a child with sickle cell disease. Pediatr Infect Dis J. 2002;21:979-81 pubmed
    ..The infection did not resolve with antibiotic therapy alone, but was cured after surgical debridement and hyperbaric oxygen therapy...
  3. Swidsinski A, Dörffel Y, Loening Baucke V, Theissig F, Rückert J, Ismail M, et al. Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum/necrophorum. Gut. 2011;60:34-40 pubmed publisher
    ..Acute appendicitis is a local intestinal inflammation with unclear origin. The aim was to test whether bacteria in appendicitis differ in composition to bacteria found in caecal biopsies from healthy and disease controls...
  4. Jalava J, Eerola E. Phylogenetic analysis of Fusobacterium alocis and Fusobacterium sulci based on 16S rRNA gene sequences: proposal of Filifactor alocis (Cato, Moore and Moore) comb. nov. and Eubacterium sulci (Cato, Moore and Moore) comb. nov. Int J Syst Bacteriol. 1999;49 Pt 4:1375-9 pubmed
    ..Two new combinations are proposed: Filifactor alocis (Cato, Moore and Moore) comb. nov. (type strain ATCC 35896T) and Eubacterium sulci (Cato, Moore and Moore) comb. nov. (type strain ATCC 35585T)...
  5. Williams M, Kerber C, Tergin H. Unusual presentation of Lemierre's syndrome due to Fusobacterium nucleatum. J Clin Microbiol. 2003;41:3445-8 pubmed
    ..This is the first case report of Lemierre's syndrome due to thrombophlebitis of the external jugular vein. The patient had a rapid clinical response to anticoagulation and antibiotics, as supported by anecdotal evidence...
  6. Jaremko J, Kirton A, Brenner J. A 12-year-old girl with pharyngitis, meningitis and sinovenous thrombosis. CMAJ. 2003;169:811-2 pubmed
  7. Ehlers Klug T, Rusan M, Fuursted K, Ovesen T. Fusobacterium necrophorum: most prevalent pathogen in peritonsillar abscess in Denmark. Clin Infect Dis. 2009;49:1467-72 pubmed publisher
    ..The purpose of the present study was to describe the epidemiology and bacteriology of PTA in Denmark, with particular emphasis on correlations between microbiological, clinical, and laboratory data...
  8. Liu P, Shi W, Zhu W, Smith J, Hsieh S, Gallo R, et al. Vaccination targeting surface FomA of Fusobacterium nucleatum against bacterial co-aggregation: Implication for treatment of periodontal infection and halitosis. Vaccine. 2010;28:3496-505 pubmed publisher
    ..nucleatum co-opts P. gingivalis to exacerbate gum infections. FomA is highlighted as a potential target for development of new therapeutics against periodontal infection and halitosis in humans...
  9. Guo D, Sun D, Wu R, Yang H, Zheng J, Fan C, et al. An indirect ELISA for serodiagnosis of cattle footrot caused by Fusobacterium necrophorum. Anaerobe. 2010;16:317-20 pubmed publisher
    ..43%, and relative specificity of rL-ELISA to nL-ELISA was 94.26%. These data demonstrated the rL-ELISA would have a potential use for early diagnosis of cattle footrot caused by F. necrophorum...

More Information

Publications105 found, 100 shown here

  1. Nazifi S, Esmailnezhad Z, Haghkhah M, Ghadirian S, Mirzaei A. Acute phase response in lame cattle with interdigital dermatitis. World J Microbiol Biotechnol. 2012;28:1791-6 pubmed publisher
    ..3 times increase in the lameness group compared to the control. In the lameness group, significant associations were observed for Hp with PBSA, SAA with TSA, TSA with PBSA, TSA with LBSA, PBSA with LBSA, and SAA with IFN-?...
  2. Chirinos J, Lichtstein D, Garcia J, Tamariz L. The evolution of Lemierre syndrome: report of 2 cases and review of the literature. Medicine (Baltimore). 2002;81:458-65 pubmed
    ..4%), but significant morbidity occurred, which was likely preventable by early diagnosis and treatment. The pathophysiology, natural history, diagnostic methods for internal jugular vein thrombosis, and management are discussed...
  3. Narayanan S, Chengappa M, Stewart G, Nagaraja T. Immunogenicity and protective effects of truncated recombinant leukotoxin proteins of Fusobacterium necrophorum in mice. Vet Microbiol. 2003;93:335-47 pubmed
    ..necrophorum carries epitopes that induce protective immunity against experimental fusobacterial infection, thus providing further evidence to the importance of leukotoxin as a major virulence factor...
  4. Jacinto R, Montagner F, Signoretti F, Almeida G, Gomes B. Frequency, microbial interactions, and antimicrobial susceptibility of Fusobacterium nucleatum and Fusobacterium necrophorum isolated from primary endodontic infections. J Endod. 2008;34:1451-6 pubmed publisher
    ..Amoxicillin is a useful antibiotic against F. nucleatum and F. necrophorum in endodontic infections and has been prescribed as the first choice in Brazil...
  5. Han X, Weinberg J, Prabhu S, Hassenbusch S, Fuller G, Tarrand J, et al. Fusobacterial brain abscess: a review of five cases and an analysis of possible pathogenesis. J Neurosurg. 2003;99:693-700 pubmed
    ..The cases of five patients with fusobacterial brain abscess are presented. The authors discuss their attempt to determine the pathogenesis...
  6. Schmid T, Miskin H, Schlesinger Y, Argaman Z, Kleid D. Respiratory failure and hypercoagulability in a toddler with Lemierre's syndrome. Pediatrics. 2005;115:e620-2 pubmed
    ..Blood cultures were positive for Fusobacterium necrophorum. Screening for hypercoagulability revealed 2 known risk factors: a mutation in the prothrombin gene and elevated lipoprotein a...
  7. Le Moal G, Juhel L, Grollier G, Godet C, Azais I, Roblot F. Vertebral osteomyelitis due to Fusobacterium species: report of three cases and review of the literature. J Infect. 2005;51:E5-9 pubmed
    ..Clindamycin is the most appropriate antibiotic. The outcome seems to be very good without relapse with appropriate treatment compared to pyogenic vertebral osteomyelitis...
  8. Zhou H, Bennett G, Hickford J. Variation in Fusobacterium necrophorum strains present on the hooves of footrot infected sheep, goats and cattle. Vet Microbiol. 2009;135:363-7 pubmed publisher
    ..necrophorum is present in each case. This is in contrast to D. nodosus in footrot infections, which have been demonstrated to have up to seven strains infecting a single hoof...
  9. Subirana Pozo F, Serra Carreras J, Lorente Guerrero J, Crego de Pablos F, Garcia Lopez M, Grasa Pérez J, et al. [Lemiere's syndrome. Thrombophlebitis of the internal jugular vein induced by oropharyngeal lesion. A case report]. An Otorrinolaringol Ibero Am. 2001;28:419-30 pubmed
    ..We also undertake a review of Lemierre's syndrome cases published within the last seven years in the English and Spanish literature, giving special attention to diagnostical methods and therapeutical strategies. ..
  10. Duong M, Wenger J. Lemierre syndrome. Pediatr Emerg Care. 2005;21:589-93 pubmed
    ..We discuss a case of Lemierre syndrome in a 17-year-old girl and review the pathophysiology of Fusobacterium necrobacillosis and diagnosis and treatment of Lemierre syndrome. ..
  11. Baills M, Freydiere A, Floret D. [Septic osteomyelitis of the hip after Fusobacterium necrophorum pharyngitis]. Med Mal Infect. 2010;40:544-7 pubmed publisher
    ..Careful attention should be paid to common ENT infections with an unfavorable evolution despite antibiotics. PCR has become a very interesting tool to document bone and joints bacterial infections when cultures are negative. ..
  12. Gulmez D, Alp S, Topeli Iskit A, Akova M, Hascelik G. [Pneumonia caused by Fusobacterium necrophorum: is Lemierre syndrome still current?]. Mikrobiyol Bul. 2011;45:729-34 pubmed
  13. Ramirez S, Hild T, Rudolph C, Sty J, Kehl S, Havens P, et al. Increased diagnosis of Lemierre syndrome and other Fusobacterium necrophorum infections at a Children's Hospital. Pediatrics. 2003;112:e380 pubmed
    ..LS is an oropharyngeal infection characterized by septic thrombophlebitis of head and neck veins, complicated by dissemination of septic emboli to pulmonary and systemic sites...
  14. Campoamor Serrano M, Galiana Martín D, Noval Menéndez J, de la Fuente García B. [Hepatic abscesses and hepatic venous thrombosis due to Fusobacterium necrophorum septicemia: Lemierre syndrome variant]. Med Clin (Barc). 2007;129:197-8 pubmed
  15. Schlafer S, Riep B, Griffen A, Petrich A, Hübner J, Berning M, et al. Filifactor alocis--involvement in periodontal biofilms. BMC Microbiol. 2010;10:66 pubmed publisher
    ..F. alocis is likely to make a relevant contribution to the pathogenetic structure of biofilms accounting for periodontal inflammation and can be considered an excellent marker organism for periodontal disease. ..
  16. Gupta S, Ghosh S, Scott M, Bainbridge B, Jiang B, Lamont R, et al. Fusobacterium nucleatum-associated beta-defensin inducer (FAD-I): identification, isolation, and functional evaluation. J Biol Chem. 2010;285:36523-31 pubmed publisher
    ..FAD-I or its derivates offer a potentially new paradigm in immunoregulatory therapeutics because they may one day be used to bolster the innate defenses of vulnerable mucosae...
  17. Kimura M, Tanikawa T, Suzuki M, Koizumi N, Kamiyama T, Imaoka K, et al. Detection of Streptobacillus spp. in feral rats by specific polymerase chain reaction. Microbiol Immunol. 2008;52:9-15 pubmed publisher
    ..rattus (30/52). The nucleotide sequence analysis of the 16S rRNA gene of Streptobacillus spp. isolated from oral swabs of feral rats showed at least two different types of bacteria among isolates from R. norvegicus and R. rattus...
  18. Velagapudi P, Turagam M, Are C, Patel H, Yekkirala L. "A forgotten disease": a case of Lemierre syndrome. ScientificWorldJournal. 2009;9:331-2 pubmed publisher
    ..Mohammed Iqbal Syed et al. Lemierre Syndrome: Two Cases and a Review. Laryngoscope, 117:1605-1610, 2007 5. Vohra A, Saiz E, Ratzan KR. A young woman with a sore throat, septicaemia, and respiratory failure. Lancet 1997; 350:928. ..
  19. Bank S, Nielsen H, Mathiasen B, Leth D, Kristensen L, Prag J. Fusobacterium necrophorum- detection and identification on a selective agar. APMIS. 2010;118:994-9 pubmed publisher
    ..Furthermore, the F. necrophorum selective agar does not require experienced laboratory technicians, require fewer subcultures, is probably less expensive and is faster to perform than other culture methods...
  20. Runge V, Wells J, Williams N. Hepatic abscesses. Magnetic resonance imaging findings using gadolinium-BOPTA. Invest Radiol. 1996;31:781-8 pubmed
    ..The appearance of a liver abscess on late scans (45 to 60 minutes) after Gd-BOPTA injection is distinct from that of nonnecrotic metastases, with diffusion of the agent into the lesion noted. ..
  21. Brook I. Two cases of diskitis attributable to anaerobic bacteria in children. Pediatrics. 2001;107:E26 pubmed
    ..Future prospective studies are warranted to elucidate the role of anaerobic bacteria in diskitis in children. ..
  22. Tadepalli S, Stewart G, Nagaraja T, Jang S, Narayanan S. Fusobacterium equinum possesses a leukotoxin gene and exhibits leukotoxin activity. Vet Microbiol. 2008;127:89-96 pubmed
    ..Our data indicated that F. equinum isolates had lktA gene and its product was toxic to equine leukocytes. Therefore, leukotoxin may be an important virulence factor in F. equinum infections. ..
  23. Brundin M, Figdor D, Sundqvist G, Sjögren U. Starvation response and growth in serum of Fusobacterium nucleatum, Peptostreptococcus anaerobius, Prevotella intermedia, and Pseudoramibacter alactolyticus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:129-34 pubmed publisher
    ..These findings point to starvation-survival capacity as a selection factor for microbial participation in post-treatment disease. ..
  24. Huggan P, Murdoch D. Fusobacterial infections: clinical spectrum and incidence of invasive disease. J Infect. 2008;57:283-9 pubmed publisher
    ..Clinically significant infections caused by members of the genus Fusobacterium are rare. We sought to describe the spectrum of clinical disease and epidemiology of these conditions presenting to an acute hospital over a five year period...
  25. McKinnon A, Black A, Lortie K, Fleming N. A case of adolescent pelvic inflammatory disease caused by a rare bacterium: Fusobacterium nucleatum. J Pediatr Adolesc Gynecol. 2013;26:e113-5 pubmed publisher
    ..This case also highlights the importance of the role of diagnostic laparoscopy in young women who have persistent pain following previous surgery due to the potential of missed pathology or subclinical infection. ..
  26. Kumar A, Anderson D, Amachawadi R, Nagaraja T, Narayanan S. Characterization of Fusobacterium necrophorum isolated from llama and alpaca. J Vet Diagn Invest. 2013;25:502-7 pubmed publisher
    ..05) toward alpaca PMNs compared to bovine PMNs. Fusobacterium necrophorum isolates from llama and alpaca are similar to bovine isolates, and leukotoxin may be a major virulence factor. ..
  27. Jakob W, Schroder H, Rudolph M, Krasiński Z, Krasinska M, Wolf O, et al. Necrobacillosis in free-living male European bison in Poland. J Wildl Dis. 2000;36:248-56 pubmed
    ..Immunolabeling and electron microscopy also suggest that these organisms are Fusobacterium sp. ..
  28. Gillis K, Seenan J, Cahill A, Tyers A, Khanna N, Edwards G, et al. An unusual infection in an injecting drug user. Scott Med J. 2011;56:59 pubmed publisher
    ..We present a case of septic thrombophlebitis secondary to Fusobacterium gonidiaformans infection in a heroin user, which demonstrates the frequently unusual nature of pathogens and presentations in this group of patients. ..
  29. Ishiguro N, Maeda A, Suzuki K, Yamana Y, Fukuya Y, Kawashima M. Three cases of perioral dermatitis related to fusobacteria treated with ?-lactam antibiotics. J Dermatolog Treat. 2014;25:507-9 pubmed publisher
    ..Fusobacteria were positive before treatment but became negative after the treatment in all of them. The ?-lactam antibiotics might be a useful treatment for perioral dermatitis, especially in cases who cannot take tetracyclines. ..
  30. Chang C, Liou C, Huang C, Lui C, Chang K. Cavernous sinus thrombosis and cerebral infarction caused by Fusobacterium nucleatum infection. Chang Gung Med J. 2004;27:459-63 pubmed
    ..We describe our experience in the management of this case of anaerobic meningitis and the unusual complication of ischemic stroke; this case suggests that more aggressive therapy in addition to empirical antibiotics may be warranted. ..
  31. Cundiff J, Djalilian H, Mafee M. Bilateral sequential petrous apicitis secondary to an anaerobic bacterium. Otolaryngol Head Neck Surg. 2006;135:969-71 pubmed
  32. Fardini Y, Wang X, Temoin S, Nithianantham S, Lee D, Shoham M, et al. Fusobacterium nucleatum adhesin FadA binds vascular endothelial cadherin and alters endothelial integrity. Mol Microbiol. 2011;82:1468-80 pubmed publisher
    ..This may explain why F. nucleatum is often found in mixed infections. This study reveals a possible novel dissemination mechanism utilized by pathogens. ..
  33. Libeer C, Bockaert J, Van den Brande P, Zachee P, Van de Vyvere M, Geyskens W. [The Lemierre syndrome: a complicated oropharyngeal infection]. Acta Clin Belg. 2005;60:173-9 pubmed
    ..In the beginning there is often a transient hyperbilirubinemia with toxic inflammatory blood results. Under the correct antibiotic regime complete recovery can be obtained. ..
  34. Braunbeck A, Geiger E, Weber R, Maier M, Daecke W, Fiebig C, et al. [Phlegmon of the palm of the hand as initial manifestation of the Lemierre syndrome]. Unfallchirurg. 2010;113:155-8 pubmed publisher
    ..In this case, positron emission tomography (PET) was revealed to be an appropriate instrument to determine the extent of the disease in a one step procedure. ..
  35. Christensen A, Kirkegaard M, Randrup T, Klug T. Biochemical tests cannot differentiate between tonsillar and middle ear-derived infections. Dan Med J. 2013;60:A4623 pubmed
    ..None of the infection markers studied were useful for differential diagnostics. not relevant. not relevant. ..
  36. do Vale C, de Oliveira Fraga L, Costa A, Tavares C, Martins Filho O, de Macedo Farias L, et al. Antiproliferative activity of Actinobacillus (Haemophilus) actinomycetemcomitans and Fusobacterium nucleatum in peripheral blood mononuclear cells. Res Microbiol. 2004;155:731-40 pubmed
    ..H.) actinomycetemcomitans and F. nucleatum cytoplasmic extracts in their antiproliferative activity, regarding the antigen concentration required for maximum inhibition and their vulnerability to heating and proteolytic treatment. ..
  37. Edwards A, Grossman T, Rudney J. Fusobacterium nucleatum transports noninvasive Streptococcus cristatus into human epithelial cells. Infect Immun. 2006;74:654-62 pubmed
    ..These studies indicate that F. nucleatum may facilitate the colonization of epithelial cells by bacteria unable to adhere or invade directly...
  38. Karkos P, Asrani S, Karkos C, Leong S, Theochari E, Alexopoulou T, et al. Lemierre's syndrome: A systematic review. Laryngoscope. 2009;119:1552-9 pubmed publisher
    ..Successful management rests on the awareness of the condition, a high index of suspicion, and a multidisciplinary team approach. ..
  39. Nair P, Sundqvist G, Sjögren U. Experimental evidence supports the abscess theory of development of radicular cysts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106:294-303 pubmed publisher
    ..This finding provides strong experimental evidence in support of the "abscess theory" of development of radicular cysts. ..
  40. Nohrström E, Mattila T, Pettila V, Kuusela P, Carlson P, Kentala E, et al. Clinical spectrum of bacteraemic Fusobacterium infections: from septic shock to nosocomial bacteraemia. Scand J Infect Dis. 2011;43:463-70 pubmed publisher
    ..However, F. necrophorum infections present more frequently without any apparent venous thrombosis and may be accompanied by abscesses. ..
  41. Haddad N, Morris T, Dhillon R, Gibbon F. Unusual neurological presentation of Fusobacterium necrophorum disease. BMJ Case Rep. 2016;2016: pubmed publisher
    ..Awareness of this organism is important. The combination of source control together with appropriate antibiotic use was crucial in controlling the infection. ..
  42. Arat Y, Shetlar D, Rose J. Blindness from septic thrombophlebitis of the orbit and cavernous sinus caused by Fusobacterium nucleatum. Arch Ophthalmol. 2004;122:652-4 pubmed
  43. Heininger A, Will B, Krueger W, Kottler B, Unertl K, Stark M. [Detection and identification of the pathogenic cause of a brain abscess by molecular genetic methods]. Anaesthesist. 2004;53:830-5 pubmed
    ..which was only diagnosed by broad spectrum PCR. To our knowledge this is the second report about a brain abscess, where Fusobacterium spp. was identified only by broad spectrum PCR and subsequent DNA sequencing. ..
  44. Centor R, Atkinson T, Ratliff A, Xiao L, Crabb D, Estrada C, et al. The clinical presentation of Fusobacterium-positive and streptococcal-positive pharyngitis in a university health clinic: a cross-sectional study. Ann Intern Med. 2015;162:241-7 pubmed publisher
    ..necrophorum-positive pharyngitis clinically resembles streptococcal pharyngitis. University of Alabama at Birmingham and the Justin E. Rodgers Foundation. ..
  45. Klinge L, Vester U, Schaper J, Hoyer P. Severe Fusobacteria infections (Lemierre syndrome) in two boys. Eur J Pediatr. 2002;161:616-8 pubmed
    ..Case 2 presented with a life-threatening septicaemia due to a retropharyngeal abscess and perforated otitis media followed by osteomyelitis of the atlas and thrombosis of the left sigmoid sinus and internal jugular vein...
  46. Kato C, Mikami M, Suzuki A, Saito K. The reduction of Fusobacterium nucleatum in mice is irrelevant to the nitric oxide induced by iNOS. Microbiol Immunol. 2003;47:27-35 pubmed
    ..However the significant amounts of NO derived from the iNOS synthesized in the LB group between 12 hr and 24 hr after injection of LFn were not involved in the Fn reduction. ..
  47. Megged O, Assous M, Miskin H, Peleg U, Schlesinger Y. Neurologic manifestations of Fusobacterium infections in children. Eur J Pediatr. 2013;172:77-83 pubmed publisher
    ..The purpose of this study was to review our experience with pediatric Fusobacterium infections. The medical records of all children aged 0 to 18 years who were diagnosed between 1999 and 2011 with ..
  48. Brazier J, Hall V, Yusuf E, Duerden B. Fusobacterium necrophorum infections in England and Wales 1990-2000. J Med Microbiol. 2002;51:269-72 pubmed
    ..F. necrophorum continues to be a regular but uncommon cause of bacteraemia and metastatic abscesses following an acute sore throat, especially in young, otherwise healthy adults...
  49. Chang P, Harris J, Bhumbra N, Puczynski M, Kherallah N, Lewis T, et al. Index of suspicion. Pediatr Rev. 2006;27:73-8 pubmed
  50. Castellarin M, Warren R, Freeman J, Dreolini L, Krzywinski M, Strauss J, et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Res. 2012;22:299-306 pubmed publisher
    ..5 × 10(-6)), and we observed a positive association with lymph node metastasis...
  51. Cheung W, Bellas J. Case report: Lemierre syndrome presenting with fever and pharyngitis. Am Fam Physician. 2007;75:979-80 pubmed
  52. Dorsey S. A critically ill young man with septic emboli to the lungs. J Emerg Med. 2002;22:415-7 pubmed
  53. Hayashi M, Yamawaki I, Nakata J, Watanabe N, Ohkawa S. [A case of Lemierre syndrome]. Nihon Kokyuki Gakkai Zasshi. 2003;41:651-4 pubmed
    ..Although Lemierre syndrome is a relatively uncommon disease with the potentially life-threatening complication of acute pharyngotonsillitis, this syndrome should be considered in cases of severe tonsillitis or pharyngitis...
  54. Kirsch D, Tighe D, D Antonio M, Palacios E. Lemierre's syndrome. Ear Nose Throat J. 2004;83:806 pubmed
  55. Costalat V, Cartier C, Delort P, Brunel H, Bourbotte G, Bonafe A. [Clinical case #3. Venous thrombosis of the lateral sinus]. J Radiol. 2005;86:520-2 pubmed
  56. Mittal M, Zimmerman R. Meningitis and epidural abscess related to pansinusitis. Pediatr Emerg Care. 2009;25:267-8 pubmed publisher
    ..Despite no history or examination findings suggestive of sinusitis, she was found to have pansinusitis with intracranial extension causing meningitis and epidural abscess...
  57. Chand D, Brady R, Bissler J. Hemolytic uremic syndrome in an adolescent with Fusobacterium necrophorum bacteremia. Am J Kidney Dis. 2001;37:E22 pubmed
    ..Understanding the pathophysiologic mechanisms involved in atypical HUS would guide the development of more precise therapies...
  58. Nogueira Moreira A, Fernandez Canigia L, Furman C, Chiappe V, Marcantoni M, Bianchini H. [Clinical and microbiological study of adult periodontal disease]. Rev Argent Microbiol. 2001;33:133-40 pubmed
    ..There were significant differences in the subgingival microflora between healthy and disease sites in patients with moderate and severe periodontitis...
  59. Thatcher P. Hepatic abscesses caused by Fusobacterium necrophorum as part of the Lemierre syndrome. J Clin Gastroenterol. 2003;37:196-7 pubmed
  60. Nakashita S, Onozawa Y, Hayashi H, Kawamitsu H, Amakawa T. [Fusobacterium necroforum sepsis]. Nihon Naika Gakkai Zasshi. 2003;92:2415-6 pubmed
  61. Veldhoen E, Wolfs T, van Vught A. Two cases of fatal meningitis due to Fusobacterium necrophorum. Pediatr Neurol. 2007;36:261-3 pubmed
    ..This report presents two fatal cases who presented to our pediatric intensive care unit in December 2004...
  62. Amess J, O NEILL W, Giollariabhaigh C, Dytrych J. A six-month audit of the isolation of Fusobacterium necrophorum from patients with sore throat in a district general hospital. Br J Biomed Sci. 2007;64:63-5 pubmed
    ..The results presented here indicate that F. necrophorum is second to group A haemolytic streptococci as a cause of sore throat, especially in the young adult, and introduction of routine culture should be considered...
  63. Ohkusa T, Kato K, Terao S, Chiba T, Mabe K, Murakami K, et al. Newly developed antibiotic combination therapy for ulcerative colitis: a double-blind placebo-controlled multicenter trial. Am J Gastroenterol. 2010;105:1820-9 pubmed publisher
    ..Fusobacterium varium may contribute to ulcerative colitis (UC). We conducted a double-blind placebo-controlled multicenter trial to determine whether antibiotic combination therapy induces and/or maintains remission of active UC...
  64. Weiss I, Marom T, Goldfarb A, Roth Y. Luc's abscess: the return of an old fellow. Otol Neurotol. 2010;31:776-9 pubmed publisher
    ..Luc's abscess, a subperiosteal temporal collection, is an infrequent complication with a particularly benign course...
  65. Zacharek M, Malani P, Chenoweth C. Clinical problem solving: radiology. Radiology quiz case 2: Lemierre syndrome. Arch Otolaryngol Head Neck Surg. 2002;128:597-9 pubmed
  66. Olson J, Mandava N. Bilateral intraocular involvement in Lemierre's syndrome. Br J Ophthalmol. 2006;90:249-50 pubmed
  67. Ravn T, Huniche B, Breum L, Jørgen Christensen J. Lemierre's syndrome: still an important clinical entity. Scand J Infect Dis. 2006;38:299-301 pubmed
    ..Familiarity with the signs and symptoms of Lemierre's syndrome is therefore of great importance...
  68. Boye M, Aalbaek B, Agerholm J. Fusobacterium necrophorum determined as abortifacient in sheep by laser capture microdissection and fluorescence in situ hybridization. Mol Cell Probes. 2006;20:330-6 pubmed
    ..necrophorum showed that no other bacteria could be detected in the tissue sections. We therefore conclude that F. necrophorum was the likely cause of abortion in these sheep...
  69. van Wissen M, Gerdes V, van Gorp E, Brandjes D, Soesan M. Unusual presentation of Lemierre's syndrome: two cases and a review. Blood Coagul Fibrinolysis. 2009;20:466-9 pubmed publisher
    ..necrophorum, even without the presence of clinical symptoms pointing towards thrombosis of the internal jugular vein, justifies further radiological testing for thrombophlebitis of the internal jugular vein...
  70. Heyndrickx M, Galateau Salle F, Herry I, Icard P. Pulmonary botryomycosis on a lung cavity: a rare pulmonary infection mimicking cancer. Gen Thorac Cardiovasc Surg. 2012;60:607-9 pubmed publisher
    ..Botryomycosis is a difficult diagnosis that clinically mimics actinomycosis, tuberculosis or cancer. In most cases, surgery is necessary to assess diagnosis and treatment...
  71. Rashidi A, Tahhan S, Cohee M, Goodman B. Fusobacterium nucleatum infection mimicking metastatic cancer. Indian J Gastroenterol. 2012;31:198-200 pubmed
    ..Cancer work up was negative. A liver biopsy grew Fusobacterium nucleatum. To our knowledge, F. nucleatum infection presenting with multiple liver masses and Trousseau-like syndrome has not been reported earlier...
  72. Screaton N, Ravenel J, Lehner P, Heitzman E, Flower C. Lemierre syndrome: forgotten but not extinct--report of four cases. Radiology. 1999;213:369-74 pubmed
    ..Internal jugular venous thrombosis was demonstrated at ultrasonography and contrast material-enhanced CT...
  73. Onoue S, Imai T, Kumada H, Umemoto T, Kaca W, Isshiki Y, et al. Serum antibodies of periodontitis patients compared to the lipopolysaccharides of Porphyromonas gingivalis and Fusobacterium nucleatum. Microbiol Immunol. 2003;47:51-5 pubmed
    ..gingivalis. These results suggest that the antibody measurement of patients' sera against the LPS of periodontal bacteria can be applied for the diagnosis of periodontitis...
  74. Engelke C, Rummeny E, Marten K. A patient with prolonged fever after pharyngotonsillitis. Br J Radiol. 2004;77:627-8 pubmed
  75. Constantin J, Mira J, Guerin R, Cayot Constantin S, Lesens O, Gourdon F, et al. Lemierre's syndrome and genetic polymorphisms: a case report. BMC Infect Dis. 2006;6:115 pubmed
    ..Lemierre's syndrome presents a classic clinical picture, the pathophysiology of which remains obscure. Attempts have been made to trace genetic predispositions that modify the host detection of pathogen or the resultant systemic reaction...
  76. Airoldi J, Pereira L, Cotter A, Gomez R, Berghella V, Prasertcharoensuk W, et al. Amniocentesis prior to physical exam-indicated cerclage in women with midtrimester cervical dilation: results from the expectant management compared to Physical Exam-indicated Cerclage international cohort study. Am J Perinatol. 2009;26:63-8 pubmed publisher
    ..90). The performance of an amniocentesis prior to cerclage did not independently contribute to PTB less than 28 weeks...
  77. Drouet A, Le Moigne F, Donat A, Guilloton L, Felten D. [Brain abscess as the first clinical manifestation of isolated pulmonary arteriovenous malformation without Rendu-Osler disease]. Rev Neurol (Paris). 2011;167:29-34 pubmed publisher
    ..Brain abscesses occur in 5 to 13 % of patients with pulmonary arteriovenous malformation (PAVM), more often present in Rendu-Osler-Weber disease or hereditary hemorrhagic telangiectasia (HHT)...
  78. Sabatiello M, Vanhooteghem O, Mostinckx S, de la Brassinne M. The Pott's puffy tumor: an unusual complication of frontal sinusitis, methods for its detection. Pediatr Dermatol. 2010;27:406-8 pubmed publisher
    ..Given that, superficial temporal artery pseudoaneurysms might be interpreted as a cyst or lipoma, it is imperative that physicians be aware of their presentation...
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    ..The patient was treated with anticoagulation and a 10-week course of intravenous antibiotics, including ceftriaxone and metronidazole...
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    ..The aim of this study is to explore the effect of high molecular weight cranberry constituent (non-dialyzable material [NDM]) on the virulence of a mixed infection with Porphyromonas gingivalis and Fusobacterium nucleatum in mice...
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    ..F. necrophorum, a putative trigger organism for noma may gain a foothold only when certain staging conditions (i.e., lowered host resistance and/or oral lesion) are present...
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    ..The incidence of fusobacterium infections appears to be increasing, and we present three cases of fusobacteriosis who presented with features of ..
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    ..Trauma was the most important reported cause of farmed white-tailed deer mortality; necrobacillosis was a major cause of morbidity and mortality, especially in fawns...
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    ..These results suggest that the DNA probe Fu12 and the three pairs of PCR primers could be useful in the identification of F. nucleatum ATCC 25586T, especially with regard to the determination of the authenticity of the strain...
  86. Shin H, Kim M, Kim H, Park S, Kim D, Baek D, et al. Development of strain-specific PCR primers for the identification of Fusobacterium nucleatum subsp. fusiforme ATCC 51190(T) and subsp. vincentii ATCC 49256(T). Anaerobe. 2010;16:43-6 pubmed publisher
    ..These results suggest that the two sets of PCR primers could be used to identify F. nucleatum subsp. fusiforme ATCC 51190(T) and F. nucleatum subsp. vincentii ATCC 49256(T), particularly for ascertaining the authenticity of the strain...
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    ..This condition was so rare that, historically, it became known as the "forgotten disease," but an increasing frequency of reports indicates that Lemierre syndrome may not be so uncommon...
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    ..pyogenes (fimA and plo) was associated with metritis (fimA) when detected at 1-3 DIM and endometritis (fimA and plo) when detected at 8-10 and 34-36 DIM...
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    ..The 16S-23S rRNA gene ITS can be a useful tool to determine the origin of F. nucleatum. The results of this study strongly indicate that F. nucleatum subsp. polymorphum of oral origin could be involved with pregnancy complications...
  91. Huang S, Yang Z, Zou D, Dong D, Liu A, Liu W, et al. Rapid detection of nusG and fadA in Fusobacterium nucleatum by loop-mediated isothermal amplification. J Med Microbiol. 2016;65:760-9 pubmed publisher
    ..nucleatum. The LAMP method constitutes a sensitive and specific visual assay for the rapid detection of the pathogen F. nucleatum. ..
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