yersinia infections

Summary

Summary: Infections with bacteria of the genus YERSINIA.

Top Publications

  1. Zhan L, Han Y, Yang L, Geng J, Li Y, Gao H, et al. The cyclic AMP receptor protein, CRP, is required for both virulence and expression of the minimal CRP regulon in Yersinia pestis biovar microtus. Infect Immun. 2008;76:5028-37 pubmed publisher
  2. Trulzsch K, Geginat G, Sporleder T, Ruckdeschel K, Hoffmann R, Heesemann J, et al. Yersinia outer protein P inhibits CD8 T cell priming in the mouse infection model. J Immunol. 2005;174:4244-51 pubmed
    ..Using this approach we could further show that the listeriolysin O-specific CD8 T cells generated in vivo by the yopP mutant are functional and are able to protect mice against a lethal challenge with wild type Listeria. ..
  3. Wortberg F, Nardy E, Contzen M, Rau J. Identification of Yersinia ruckeri from diseased salmonid fish by Fourier transform infrared spectroscopy. J Fish Dis. 2012;35:1-10 pubmed publisher
    ..The differentiation of sorbitol-positive variants of Y. ruckeri using FT-IR was demonstrated...
  4. Zhou H, Monack D, Kayagaki N, Wertz I, Yin J, Wolf B, et al. Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation. J Exp Med. 2005;202:1327-32 pubmed
    ..Moreover, an in vitro assay was established to demonstrate directly the deubiquitinating activity of purified YopJ. ..
  5. Raida M, Holten Andersen L, Buchmann K. Association between Yersinia ruckeri infection, cytokine expression and survival in rainbow trout (Oncorhynchus mykiss). Fish Shellfish Immunol. 2011;30:1257-64 pubmed publisher
    ..Thus, less susceptible fish are protected by other factors and contract merely a weak non-lethal infection eliciting no or a weak cytokine response...
  6. Mikula K, Kolodziejczyk R, Goldman A. Yersinia infection tools-characterization of structure and function of adhesins. Front Cell Infect Microbiol. 2012;2:169 pubmed publisher
    ..Those extracellular regions define the activity of each adhesin. This review focuses on the structure and function of these important molecules, and their role in pathogenesis. ..
  7. Białas N, Kasperkiewicz K, Radziejewska Lebrecht J, Skurnik M. Bacterial cell surface structures in Yersinia enterocolitica. Arch Immunol Ther Exp (Warsz). 2012;60:199-209 pubmed publisher
    ..These structures ensure the correct architecture of the OM, provide adhesive properties as well as resistance to antimicrobial peptides and to host innate immune response mechanisms...
  8. Raida M, Buchmann K. Bath vaccination of rainbow trout (Oncorhynchus mykiss Walbaum) against Yersinia ruckeri: effects of temperature on protection and gene expression. Vaccine. 2008;26:1050-62 pubmed publisher
    ..Expression of cellular factors such as CD8alpha was significantly increased in the protected trout and this suggests that cellular factors including cytotoxic T-cells could play a role in immunity against Y. ruckeri. ..
  9. Gerke C, Falkow S, Chien Y. The adaptor molecules LAT and SLP-76 are specifically targeted by Yersinia to inhibit T cell activation. J Exp Med. 2005;201:361-71 pubmed
    ..This is the first example showing that a pathogen targets these adaptor proteins in the TCR signaling pathway, suggesting a novel mechanism by which pathogens may efficiently alter T cell-mediated immune responses...

More Information

Publications84

  1. Trulzsch K, Oellerich M, Heesemann J. Invasion and dissemination of Yersinia enterocolitica in the mouse infection model. Adv Exp Med Biol. 2007;603:279-85 pubmed
    ..Only very few yersiniae invade Peyer's patches and establish just a very few monoclonal microabscesses. This is due to both Yersinia and host specific factors. ..
  2. Perdikogianni C, Galanakis E, Michalakis M, Giannoussi E, Maraki S, Tselentis Y, et al. Yersinia enterocolitica infection mimicking surgical conditions. Pediatr Surg Int. 2006;22:589-92 pubmed
    ..Y. enterocolitica enteritis manifestations can infrequently mimic appendicitis or other surgical conditions but should remain in the differential diagnosis of children presenting with an acute abdomen. ..
  3. Mallik S, Virdi J. Genetic relationships between clinical and non-clinical strains of Yersinia enterocolitica biovar 1A as revealed by multilocus enzyme electrophoresis and multilocus restriction typing. BMC Microbiol. 2010;10:158 pubmed publisher
    ..BURST analysis of MLRT data nevertheless provided newer insights into the probable evolution of clinical strains from aquatic strains. ..
  4. Falcão J, Falcão D, Pitondo Silva A, Malaspina A, Brocchi M. Molecular typing and virulence markers of Yersinia enterocolitica strains from human, animal and food origins isolated between 1968 and 2000 in Brazil. J Med Microbiol. 2006;55:1539-48 pubmed
    ..enterocolitica for human infections in Brazil, an epidemiological aspect that has not been investigated in this country, confirming data from other parts of the world...
  5. Young G. The Ysa type 3 secretion system of Yersinia enterocolitica biovar 1B. Adv Exp Med Biol. 2007;603:286-97 pubmed
    ..enterocolitica interactions with the host. In part, the Ysa T3S system targets the innate immune response to suppress the ability of the host to rapidly clear an infection. ..
  6. Trcek J, Fuchs T, Trulzsch K. Analysis of Yersinia enterocolitica invasin expression in vitro and in vivo using a novel luxCDABE reporter system. Microbiology. 2010;156:2734-45 pubmed publisher
  7. Walker K, Maltez V, Hall J, Vitko N, Miller V. A phenotype at last: essential role for the Yersinia enterocolitica Ysa type III secretion system in a Drosophila melanogaster S2 cell model. Infect Immun. 2013;81:2478-87 pubmed publisher
    ..Establishment of S2 cells as a model for Y. enterocolitica infection provides a versatile tool to elucidate the role of the Ysa T3SS in the life cycle of this gastrointestinal pathogen. ..
  8. Gröbner S, Schulz S, Soldanova I, Gunst D, Waibel M, Wesselborg S, et al. Absence of Toll-like receptor 4 signaling results in delayed Yersinia enterocolitica YopP-induced cell death of dendritic cells. Infect Immun. 2007;75:512-7 pubmed
    ..Later (>4 h), DC die independent of TLR4 signaling. In TLR4-deficient DC caspase 8 cleavage is delayed, indicating that TLR4 signaling accelerates caspase 8 activation, leading to DC death. ..
  9. Raida M, Buchmann K. Development of adaptive immunity in rainbow trout, Oncorhynchus mykiss (Walbaum) surviving an infection with Yersinia ruckeri. Fish Shellfish Immunol. 2008;25:533-41 pubmed publisher
    ..This would explain the relatively fast elimination of the bacteria during the secondary infection whereby the activation of cytokines becomes less pronounced. ..
  10. Leo J, Skurnik M. Adhesins of human pathogens from the genus Yersinia. Adv Exp Med Biol. 2011;715:1-15 pubmed publisher
    ..Also the plasminogen activator of Y. pestis can mediate adherence to host cells. Although the adhesins of the pathogenic yersiniae have been studied extensively, their exact roles in the biology of infection remain elusive...
  11. Batzilla J, Antonenka U, Höper D, Heesemann J, Rakin A. Yersinia enterocolitica palearctica serobiotype O:3/4--a successful group of emerging zoonotic pathogens. BMC Genomics. 2011;12:348 pubmed publisher
    ..enterocolitica ssp. enterocolitica 8081 O:8/1B to address the peculiarities of the O:3/4 group...
  12. Golubov A, Gierczynski R, Heesemann J, Rakin A. A novel insertion sequence element, IS Yen2, as an epidemiological marker for weakly pathogenic bioserotypes of Yersinia enterocolitica. Int J Med Microbiol. 2005;295:213-26 pubmed
    ..Distribution of the different groups of IS elements in two Y. enterocolitica pathotypes is in favor of the parallel evolution of American and European Y. enterocolitica strains. ..
  13. Bergsbaken T, Cookson B. Macrophage activation redirects yersinia-infected host cell death from apoptosis to caspase-1-dependent pyroptosis. PLoS Pathog. 2007;3:e161 pubmed
  14. Heroven A, Sest M, Pisano F, Scheb Wetzel M, Steinmann R, Böhme K, et al. Crp induces switching of the CsrB and CsrC RNAs in Yersinia pseudotuberculosis and links nutritional status to virulence. Front Cell Infect Microbiol. 2012;2:158 pubmed publisher
  15. McNally A, La Ragione R, Best A, Manning G, Newell D. An aflagellate mutant Yersinia enterocolitica biotype 1A strain displays altered invasion of epithelial cells, persistence in macrophages, and cytokine secretion profiles in vitro. Microbiology. 2007;153:1339-49 pubmed
    ..Preliminary studies using porcine in vitro organ culture (IVOC) tissue suggested that the flagella mutant was also attenuated in its ability to colonize intestinal tissue...
  16. Viboud G, Bliska J. Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis. Annu Rev Microbiol. 2005;59:69-89 pubmed
    ..This review focuses on the biochemical functions of Yops, the signaling pathways they modulate, and the role of these proteins in Yersinia virulence...
  17. Martínez P, Fredriksson Ahomaa M, Pallotti A, Rosmini R, Houf K, Korkeala H. Variation in the prevalence of enteropathogenic Yersinia in slaughter pigs from Belgium, Italy, and Spain. Foodborne Pathog Dis. 2011;8:445-50 pubmed publisher
    ..enterocolitica in Belgium, Italy, and Spain. Bioserotype 4/O:3 of Y. enterocolitica and bioserotypes 2/O:3 and 1/O:1 of Y. pseudotuberculosis have been shown to predominate...
  18. Bastardo A, Ravelo C, Romalde J. Multilocus sequence typing reveals high genetic diversity and epidemic population structure for the fish pathogen Yersinia ruckeri. Environ Microbiol. 2012;14:1888-97 pubmed publisher
    ..It was also possible to associate some unique ST with isolates from recent outbreaks in vaccinated salmonid fish...
  19. Autenrieth S, Linzer T, Hiller C, Keller B, Warnke P, Köberle M, et al. Immune evasion by Yersinia enterocolitica: differential targeting of dendritic cell subpopulations in vivo. PLoS Pathog. 2010;6:e1001212 pubmed publisher
    ..These events may contribute to reduced T-cell proliferation and immune evasion of Ye...
  20. Haig S, Davies R, Welch T, Reese R, Verner Jeffreys D. Comparative susceptibility of Atlantic salmon and rainbow trout to Yersinia ruckeri: relationship to O antigen serotype and resistance to serum killing. Vet Microbiol. 2011;147:155-61 pubmed publisher
    ..Overall, strains recovered from infected salmon possess a wider range of phenotypic properties (relative virulence, O serotype and possession of serum-resistance factors), compared to ERM-causing rainbow trout isolates...
  21. Nikolaou K, Hensel A, Bartling C, Tomaso H, Arnold T, Rösler U, et al. Prevalence of anti-Yersinia outer protein antibodies in goats in lower saxony. J Vet Med B Infect Dis Vet Public Health. 2005;52:17-24 pubmed
    ..The impact on consumer health, i.e. especially for risk groups-like people allergic to cow milk and the impact on the profit of a farm will have to be elucidated in further studies...
  22. Porter C, Choi D, Cash B, Pimentel M, Murray J, May L, et al. Pathogen-specific risk of chronic gastrointestinal disorders following bacterial causes of foodborne illness. BMC Gastroenterol. 2013;13:46 pubmed publisher
    ..We utilized a US Department of Defense medical encounter database to evaluate the risk of several gastrointestinal disorders following select foodborne infections...
  23. Axler DiPerte G, Hinchliffe S, Wren B, Darwin A. YtxR acts as an overriding transcriptional off switch for the Yersinia enterocolitica Ysc-Yop type 3 secretion system. J Bacteriol. 2009;191:514-24 pubmed publisher
    ..Therefore, YtxR is a newly identified regulator of the ysc-yop genes that can act as an overriding off switch for this critical virulence system...
  24. Onuk E, Ciftci A, Findik A, Ciftci G, Altun S, Balta F, et al. Phenotypic and molecular characterization of Yersinia ruckeri isolates from rainbow trout (Oncorhynchus mykiss, Walbaum, 1792) in Turkey. Berl Munch Tierarztl Wochenschr. 2011;124:320-8 pubmed
  25. Zheng H, Sun Y, Lin S, Mao Z, Jiang B. Yersinia enterocolitica infection in diarrheal patients. Eur J Clin Microbiol Infect Dis. 2008;27:741-52 pubmed publisher
    ..During autumn-winter months, clinicians should pay more attention to clinical manifestation, early diagnosis, and treatment with susceptible antibiotics of yersiniosis and its complications, targeting high-risk patients...
  26. Al Dahouk S, Nockler K, Tomaso H, Splettstoesser W, Jungersen G, Riber U, et al. Seroprevalence of brucellosis, tularemia, and yersiniosis in wild boars (Sus scrofa) from north-eastern Germany. J Vet Med B Infect Dis Vet Public Health. 2005;52:444-55 pubmed
    ..Only careful and systematic monitoring will help to prevent the (re)emergence of these zoonotic diseases in domestic animals and consequently human infection...
  27. Fouz B, Zarza C, Amaro C. First description of non-motile Yersinia ruckeri serovar I strains causing disease in rainbow trout, Oncorhynchus mykiss (Walbaum), cultured in Spain. J Fish Dis. 2006;29:339-46 pubmed
    ..The occurrence of this emergent pathogen in Spanish continental aquaculture from its first isolation in 2001 to date is also documented...
  28. Montagner C, Arquint C, Cornelis G. Translocators YopB and YopD from Yersinia enterocolitica form a multimeric integral membrane complex in eukaryotic cell membranes. J Bacteriol. 2011;193:6923-8 pubmed publisher
    ..This heteropolymeric YopBD complex could be copurified after solubilization in 0.5% dodecyl maltoside but not visualized in the electron microscope. We speculate that this complex may not be stable and rigid but only transient...
  29. Köberle M, Klein Günther A, Schütz M, Fritz M, Berchtold S, Tolosa E, et al. Yersinia enterocolitica targets cells of the innate and adaptive immune system by injection of Yops in a mouse infection model. PLoS Pathog. 2009;5:e1000551 pubmed publisher
    ..The YopE-beta-lactamase hybrid protein reporter system provides new insights into the modulation of host cell and immune responses by Ye Yops...
  30. Handley S, Dube P, Miller V. Histamine signaling through the H(2) receptor in the Peyer's patch is important for controlling Yersinia enterocolitica infection. Proc Natl Acad Sci U S A. 2006;103:9268-73 pubmed
    ..In this study, we provide evidence that histamine signaling through the histamine H(2) but not the H(1) receptor is important for controlling Y. enterocolitica infection within the Peyer's patches and mesenteric lymph nodes of mice...
  31. Heise T, Dersch P. Identification of a domain in Yersinia virulence factor YadA that is crucial for extracellular matrix-specific cell adhesion and uptake. Proc Natl Acad Sci U S A. 2006;103:3375-80 pubmed
    ..We conclude that even small variations in adhesion factors can provoke major differences in the virulence properties of related pathogens...
  32. Bhagat N, Virdi J. The enigma of Yersinia enterocolitica biovar 1A. Crit Rev Microbiol. 2011;37:25-39 pubmed publisher
    ..These studies should also take into account the clonal groups of biovar 1A...
  33. Rosner B, Stark K, Hohle M, Werber D. Risk factors for sporadic Yersinia enterocolitica infections, Germany 2009-2010. Epidemiol Infect. 2012;140:1738-47 pubmed publisher
    ..Prevention efforts should specifically target parents and caregivers of young children and focus on the high infection risk associated with consumption of raw minced pork...
  34. Pérez Gutiérrez C, Llobet E, Llompart C, Reinés M, Bengoechea J. Role of lipid A acylation in Yersinia enterocolitica virulence. Infect Immun. 2010;78:2768-81 pubmed publisher
    ..The levels of pYV-encoded virulence factors Yops and YadA in the acyltransferase mutants were not affected. Finally, we show that only the htrB mutant was attenuated in vivo...
  35. Rein s M, Llobet E, Llompart C, Moranta D, P rez Guti rrez C, Bengoechea J. Molecular basis of Yersinia enterocolitica temperature-dependent resistance to antimicrobial peptides. J Bacteriol. 2012;194:3173-88 pubmed publisher
    ..However, rovA expression reached wild-type levels in the phoPQ pmrAB mutant background, hence indicating the existence of an unknown regulatory network controlling rovA expression in this background...
  36. Gierczyński R, Golubov A, Neubauer H, Pham J, Rakin A. Development of multiple-locus variable-number tandem-repeat analysis for Yersinia enterocolitica subsp. palearctica and its application to bioserogroup 4/O3 subtyping. J Clin Microbiol. 2007;45:2508-15 pubmed
    ..palearctica O9 and O5,27, there was only a minor correlation between the MLVA genotypes and serogroups. MLVA may be a helpful tool for epidemiological investigations of Y. enterocolitica subsp. palearctica outbreaks...
  37. Chettri J, Raida M, Kania P, Buchmann K. Differential immune response of rainbow trout (Oncorhynchus mykiss) at early developmental stages (larvae and fry) against the bacterial pathogen Yersinia ruckeri. Dev Comp Immunol. 2012;36:463-74 pubmed publisher
    ..A dense covering of surfaces of gill filaments by IgT antibody in the young fish suggest a role of this antibody as innate immune factor at early developmental stages...
  38. Gröbner S, Autenrieth S, Soldanova I, Gunst D, Schaller M, Bohn E, et al. Yersinia YopP-induced apoptotic cell death in murine dendritic cells is partially independent from action of caspases and exhibits necrosis-like features. Apoptosis. 2006;11:1959-68 pubmed
    ..However, it has to be resolved if necrosis-like DC death occurs independently from apoptotic events or as an apoptotic epiphenomenon...
  39. Welch T, Verner Jeffreys D, Dalsgaard I, Wiklund T, Evenhuis J, Cabrera J, et al. Independent emergence of Yersinia ruckeri biotype 2 in the United States and Europe. Appl Environ Microbiol. 2011;77:3493-9 pubmed publisher
    ..This differentiation of distinct BT2 lineages is of critical importance for the development and validation of alternative vaccines or other treatment strategies intended for the control of BT2 strains...
  40. Fredriksson Ahomaa M, Cernela N, Hachler H, Stephan R. Yersinia enterocolitica strains associated with human infections in Switzerland 2001-2010. Eur J Clin Microbiol Infect Dis. 2012;31:1543-50 pubmed publisher
    ..Y. enterocolitica 2/O:5,27 and 2/O:9 strains showed resistance to amoxicillin/clavulanic acid and cefoxitin, but Y. enterocolitica 4/O:3 strains did not...
  41. Huovinen E, Sihvonen L, Virtanen M, Haukka K, Siitonen A, Kuusi M. Symptoms and sources of Yersinia enterocolitica-infection: a case-control study. BMC Infect Dis. 2010;10:122 pubmed publisher
    ..Also YE-like species, which can sometimes be misidentified as YE, are considered nonvirulent...
  42. Rosner B, Stark K, Werber D. Epidemiology of reported Yersinia enterocolitica infections in Germany, 2001-2008. BMC Public Health. 2010;10:337 pubmed publisher
    ..We present recent data on the epidemiology of reported yersiniosis in Germany...
  43. Batzilla J, Heesemann J, Rakin A. The pathogenic potential of Yersinia enterocolitica 1A. Int J Med Microbiol. 2011;301:556-61 pubmed publisher
    ..However, presence of known and putative virulence-associated features shared with the pathogenic serobiotypes compels to reconsider properly the pathogenic potential of this group of emerging pathogens...
  44. Renaud N, Lecci L, Courcol R, Simonet M, Gaillot O. CHROMagar Yersinia, a new chromogenic agar for screening of potentially pathogenic Yersinia enterocolitica isolates in stools. J Clin Microbiol. 2013;51:1184-7 pubmed publisher
    ..CAY reduces the workload (and thus costs) for stool analysis and can therefore be recommended for routine laboratory use...
  45. Sihvonen L, Haukka K, Kuusi M, Virtanen M, Siitonen A. Yersinia enterocolitica and Y. enterocolitica-like species in clinical stool specimens of humans: identification and prevalence of bio/serotypes in Finland. Eur J Clin Microbiol Infect Dis. 2009;28:757-65 pubmed publisher
  46. Wang X, Cui Z, Jin D, Tang L, Xia S, Wang H, et al. Distribution of pathogenic Yersinia enterocolitica in China. Eur J Clin Microbiol Infect Dis. 2009;28:1237-44 pubmed publisher
  47. DePaolo R, Kamdar K, Khakpour S, Sugiura Y, Wang W, Jabri B. A specific role for TLR1 in protective T(H)17 immunity during mucosal infection. J Exp Med. 2012;209:1437-44 pubmed publisher
    ..Furthermore, they also demonstrate that TLR2 has dual immune functions in the gut and identify TLR1 as a critical innate receptor for protective intestinal T(H)17 immunity...
  48. Zheng Y, Lilo S, Mena P, Bliska J. YopJ-induced caspase-1 activation in Yersinia-infected macrophages: independent of apoptosis, linked to necrosis, dispensable for innate host defense. PLoS ONE. 2012;7:e36019 pubmed publisher
    ..These data suggest that YopJ-induced caspase-1 activation in Yersinia-infected macrophages is a downstream consequence of necrotic cell death and is dispensable for innate host resistance to a strain with enhanced cytotoxicity...
  49. McNally A, Dalton T, La Ragione R, Stapleton K, Manning G, Newell D. Yersinia enterocolitica isolates of differing biotypes from humans and animals are adherent, invasive and persist in macrophages, but differ in cytokine secretion profiles in vitro. J Med Microbiol. 2006;55:1725-34 pubmed
    ..Infections of porcine tissue also suggested the possibility of host-tissue tropism within Y. enterocolitica subtypes...
  50. Okwori A, Martínez P, Fredriksson Ahomaa M, Agina S, Korkeala H. Pathogenic Yersinia enterocolitica 2/O:9 and Yersinia pseudotuberculosis 1/O:1 strains isolated from human and non-human sources in the Plateau State of Nigeria. Food Microbiol. 2009;26:872-5 pubmed publisher
    ..The dominating genotype of Y. enterocolitica 2/O:9 strains among humans was also found among strains isolated from pig, fermented cow milk and traditional intestine pepper soap samples...
  51. Tobback E, Decostere A, Hermans K, Haesebrouck F, Chiers K. Yersinia ruckeri infections in salmonid fish. J Fish Dis. 2007;30:257-68 pubmed
    ..The possibility of the presence of similar virulence markers and/or pathogenic mechanisms between the Yersinia species which elicit disease in humans and Y. ruckeri is also examined...
  52. Held L, Graziano G, Frank C, Rue H. Joint spatial analysis of gastrointestinal infectious diseases. Stat Methods Med Res. 2006;15:465-80 pubmed
    ..We will illustrate our approach through the analysis of gastrointestinal diseases notification data obtained from the German infectious disease surveillance system, administered by the Robert Koch Institute in Berlin...
  53. Harun N, Wang T, Secombes C. Gene expression profiling in naïve and vaccinated rainbow trout after Yersinia ruckeri infection: insights into the mechanisms of protection seen in vaccinated fish. Vaccine. 2011;29:4388-99 pubmed publisher
    ..Thus, it is possible that different types of adaptive responses are on-going within the vaccinated fish during infection with Y. ruckeri, potentially affected by the site and stage of infection...
  54. Howard S, Gaunt M, Hinds J, Witney A, Stabler R, Wren B. Application of comparative phylogenomics to study the evolution of Yersinia enterocolitica and to identify genetic differences relating to pathogenicity. J Bacteriol. 2006;188:3645-53 pubmed
    ..enterocolitica. Further analysis revealed that Y. enterocolitica does not cluster according to source (host)...
  55. Boqvist S, Pettersson H, Svensson A, Andersson Y. Sources of sporadic Yersinia enterocolitica infection in children in Sweden, 2004: a case-control study. Epidemiol Infect. 2009;137:897-905 pubmed publisher
    ..0, 95% CI 1.2-3.4). We believe that the importance of Y. enterocolitica infection in children has been neglected and that results from this study can be used to develop preventive recommendations...
  56. Fredriksson Ahomaa M, Stolle A, Korkeala H. Molecular epidemiology of Yersinia enterocolitica infections. FEMS Immunol Med Microbiol. 2006;47:315-29 pubmed
    ..Indistinguishable genotypes have also been found between human strains and dog, cat, sheep and wild rodent strains, indicating that these animals are other possible infection sources for humans...
  57. Gijsbers C, Benninga M, Büller H. Clinical and laboratory findings in 220 children with recurrent abdominal pain. Acta Paediatr. 2011;100:1028-32 pubmed publisher
    ..To investigate the clinical and laboratory findings in children with recurrent abdominal pain (RAP)...
  58. Gürtler M, Alter T, Kasimir S, Linnebur M, Fehlhaber K. Prevalence of Yersinia enterocolitica in fattening pigs. J Food Prot. 2005;68:850-4 pubmed
    ..enterocolitica to humans from pigs and pork products...
  59. Handley S, Newberry R, Miller V. Yersinia enterocolitica invasin-dependent and invasin-independent mechanisms of systemic dissemination. Infect Immun. 2005;73:8453-5 pubmed
    ..The invasin-dependent route is clearly discernible in mice devoid of intestinal Peyer's patches and mesenteric lymph nodes...
  60. Sihvonen L, Hallanvuo S, Haukka K, Skurnik M, Siitonen A. The ail gene is present in some Yersinia enterocolitica biotype 1A strains. Foodborne Pathog Dis. 2011;8:455-7 pubmed publisher
    ..The finding suggests that ail-based detection methods for Y. enterocolitica alone are insufficient to detect real pathogenic strains...
  61. El Qouqa I, El Jarou M, Samaha A, Al Afifi A, Al Jarousha A. Yersinia enterocolitica infection among children aged less than 12 years: a case-control study. Int J Infect Dis. 2011;15:e48-53 pubmed publisher
    ..A case-control study was conducted to identify risk factors, signs, and symptoms that may be associated with, Yersinia enterocolitica among children aged less than 12 years...
  62. Ryckaert J, Bossier P, D Herde K, Diez Fraile A, Sorgeloos P, Haesebrouck F, et al. Persistence of Yersinia ruckeri in trout macrophages. Fish Shellfish Immunol. 2010;29:648-55 pubmed publisher
    ..In conclusion, this study clearly demonstrates the capacity of Y. ruckeri to survive in rainbow trout macrophages in vitro as well as in vivo, confirming its facultative intracellular nature...
  63. Dube P. Interaction of Yersinia with the gut: mechanisms of pathogenesis and immune evasion. Curr Top Microbiol Immunol. 2009;337:61-91 pubmed publisher
    ..This review examines the mechanisms of immune evasion employed by the Yersinia and highlights recent advances in understanding the host-pathogen interaction...
  64. Zheng H, Sun Y, Mao Z, Jiang B. Investigation of virulence genes in clinical isolates of Yersinia enterocolitica. FEMS Immunol Med Microbiol. 2008;53:368-74 pubmed publisher
    ..Perhaps, some of them, lacking some traditional virulence genes, contain other unknown virulence markers that interact with each other and play an important role in the diverse pathogenesis of pathogenic Y. enterocolitica...
  65. Wiens G, Vallejo R. Temporal and pathogen-load dependent changes in rainbow trout (Oncorhynchus mykiss) immune response traits following challenge with biotype 2 Yersinia ruckeri. Fish Shellfish Immunol. 2010;29:639-47 pubmed publisher
    ..This study further supports the use of SAA transcript abundance and spleen somatic index as general measures of immunological status and fish health...
  66. Arias C, Olivares Fuster O, Hayden K, Shoemaker C, Grizzle J, Klesius P. First report of Yersinia ruckeri biotype 2 in the USA. J Aquat Anim Health. 2007;19:35-40 pubmed publisher
    ..ruckeri isolates. This is the first report of Y. ruckeri biotype 2 in the USA...
  67. Leo J, Elovaara H, Bihan D, Pugh N, Kilpinen S, Raynal N, et al. First analysis of a bacterial collagen-binding protein with collagen Toolkits: promiscuous binding of YadA to collagens may explain how YadA interferes with host processes. Infect Immun. 2010;78:3226-36 pubmed publisher
    ..This leads to the intriguing possibility that YadA may interfere in vivo with host processes mediated by endogenous collagen-binding proteins...
  68. Wang X, Qiu H, Jin D, Cui Z, Kan B, Xiao Y, et al. O:8 serotype Yersinia enterocolitica strains in China. Int J Food Microbiol. 2008;125:259-66 pubmed publisher
    ..This suggests the O:8 strains lacking virulence determinants may not disseminate rapidly in humans and are maintained in animal reservoirs; and therefore exhibit higher variance and divergence from the virulent type...
  69. Fredriksson Ahomaa M, Wacheck S, Koenig M, Stolle A, Stephan R. Prevalence of pathogenic Yersinia enterocolitica and Yersinia pseudotuberculosis in wild boars in Switzerland. Int J Food Microbiol. 2009;135:199-202 pubmed publisher
    ..This study shows that the prevalence of enteropathogenic Yersinia is high and both enteropathogenic Y. enterocolitica and Y. pseudotuberculosis are common findings in tonsils of wild boars in Switzerland...
  70. Kirjavainen V, Jarva H, Biedzka Sarek M, Blom A, Skurnik M, Meri S. Yersinia enterocolitica serum resistance proteins YadA and ail bind the complement regulator C4b-binding protein. PLoS Pathog. 2008;4:e1000140 pubmed publisher
    ..These findings show that Y. enterocolitica uses two proteins, YadA and Ail, to bind C4bp. Binding of C4bp could help Y. enterocolitica to evade complement-mediated clearance in the human host...
  71. Bastardo A, Bohle H, Ravelo C, Toranzo A, Romalde J. Serological and molecular heterogeneity among Yersinia ruckeri strains isolated from farmed Atlantic salmon Salmo salar in Chile. Dis Aquat Organ. 2011;93:207-14 pubmed publisher
    ..Genotyping analyses by enterobacterial repetitive intergenic consensus (ERIC-) and repetitive extragenic palindromic (REP-)PCR techniques clearly indicated intraspecific genetic diversity among Chilean Y. ruckeri strains...
  72. Fabrega A, Vila J. Yersinia enterocolitica: pathogenesis, virulence and antimicrobial resistance. Enferm Infecc Microbiol Clin. 2012;30:24-32 pubmed publisher
    ..A review of the pathogenesis, virulence and antimicrobial resistance is carried out...
  73. Evenhuis J, Cleveland B. Modulation of rainbow trout (Oncorhynchus mykiss) intestinal immune gene expression following bacterial challenge. Vet Immunol Immunopathol. 2012;146:8-17 pubmed publisher
    ..These findings demonstrate that measurable changes in immune gene expression occur in the intestine of rainbow trout following bath challenge with Y. ruckeri or injection challenge with F. psychrophilum...
  74. Wheeler R, Davies R, Dalsgaard I, Garcia J, Welch T, Wagley S, et al. Yersinia ruckeri biotype 2 isolates from mainland Europe and the UK likely represent different clonal groups. Dis Aquat Organ. 2009;84:25-33 pubmed publisher
    ..UK Atlantic salmon isolates were genetically and serologically diverse, with 12 distinct pulsotypes identified among 32 isolates...
  75. Leclercq A, Martin L, Vergnes M, Ounnoughene N, Laran J, Giraud P, et al. Fatal Yersinia enterocolitica biotype 4 serovar O:3 sepsis after red blood cell transfusion. Transfusion. 2005;45:814-8 pubmed
    ..Although posttransfusion bacterial sepsis is rare, this complication is associated with a high mortality rate...