enterobacteriaceae infections

Summary

Summary: Infections with bacteria of the family ENTEROBACTERIACEAE.

Top Publications

  1. Obeng Nkrumah N, Twum Danso K, Krogfelt K, Newman M. High levels of extended-spectrum beta-lactamases in a major teaching hospital in Ghana: the need for regular monitoring and evaluation of antibiotic resistance. Am J Trop Med Hyg. 2013;89:960-4 pubmed publisher
    ..2%) non-ESBL producers were multidrug resistant. Regular ESBL detection and evaluation of antibiotic resistance may help reduce the spread of ESBLs and antibiotic resistance in Ghana...
  2. Zilberberg M, Shorr A. Prevalence of multidrug-resistant Pseudomonas aeruginosa and carbapenem-resistant Enterobacteriaceae among specimens from hospitalized patients with pneumonia and bloodstream infections in the United States from 2000 to 2009. J Hosp Med. 2013;8:559-63 pubmed publisher
    ..Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a pathogen of concern over the past decade...
  3. Bouchillon S, Badal R, Hoban D, Hawser S. Antimicrobial susceptibility of inpatient urinary tract isolates of gram-negative bacilli in the United States: results from the study for monitoring antimicrobial resistance trends (SMART) program: 2009-2011. Clin Ther. 2013;35:872-7 pubmed publisher
    ..The Study for Monitoring Antimicrobial Resistance Trends is an ongoing global surveillance program that has monitored the susceptibilities of Gram-negative bacilli from inpatient urinary tract infections (UTIs) since late 2009...
  4. Woerther P, Burdet C, Chachaty E, Andremont A. Trends in human fecal carriage of extended-spectrum ?-lactamases in the community: toward the globalization of CTX-M. Clin Microbiol Rev. 2013;26:744-58 pubmed publisher
    ..Only a better knowledge of its dynamics and biology will lead to further development of appropriate control measures...
  5. Mielke L, Groom J, Rankin L, Seillet C, Masson F, Putoczki T, et al. TCF-1 controls ILC2 and NKp46+ROR?t+ innate lymphocyte differentiation and protection in intestinal inflammation. J Immunol. 2013;191:4383-91 pubmed publisher
    ..Collectively, our findings demonstrate an essential requirement for TCF-1 in ILC2 differentiation and reveal a link among Tcf7, Notch, and Tbx21 in NKp46(+) ILC3 development. ..
  6. Liebana E, Carattoli A, Coque T, Hasman H, Magiorakos A, Mevius D, et al. Public health risks of enterobacterial isolates producing extended-spectrum ?-lactamases or AmpC ?-lactamases in food and food-producing animals: an EU perspective of epidemiology, analytical methods, risk factors, and control options. Clin Infect Dis. 2013;56:1030-7 pubmed publisher
    ..Decreasing total antimicrobial use is also of high priority. Implementation of measures to limit strain dissemination (increasing farm biosecurity, controls in animal trade, and other general postharvest controls) are also important...
  7. Yasuike M, Takano T, Kondo H, Hirono I, Aoki T. Differential gene expression profiles in Japanese flounder (Paralichthys olivaceus) with different susceptibilities to edwardsiellosis. Fish Shellfish Immunol. 2010;29:747-52 pubmed publisher
    ..The microarray results could be useful for selective breeding to enhance disease resistance of Japanese flounder against E. tarda and for studying strategies for controlling edwardsiellosis...
  8. Falagas M, Karageorgopoulos D, Nordmann P. Therapeutic options for infections with Enterobacteriaceae producing carbapenem-hydrolyzing enzymes. Future Microbiol. 2011;6:653-66 pubmed publisher
    ..Combination antimicrobial therapy with agents exhibiting synergy might also be of benefit, until novel effective agents could become clinically available. ..
  9. Pournaras S, Vrioni G, Neou E, Dendrinos J, Dimitroulia E, Poulou A, et al. Activity of tigecycline alone and in combination with colistin and meropenem against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains by time-kill assay. Int J Antimicrob Agents. 2011;37:244-7 pubmed publisher
    ..Additional in vivo tests are warranted to assess better the killing kinetics of tigecycline combinations against KPC-producers. ..

More Information

Publications89

  1. Takano T, Matsuyama T, Oseko N, Sakai T, Kamaishi T, Nakayasu C, et al. The efficacy of five avirulent Edwardsiella tarda strains in a live vaccine against Edwardsiellosis in Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2010;29:687-93 pubmed publisher
    ..Injection with avirulent E. tarda increased the expression of cytokine genes, including interleukin-1beta (IL-1beta), type 1 interferon (IFN), and IFN-gamma in head-kidney of the Japanese flounder...
  2. Tzouvelekis L, Markogiannakis A, Psichogiou M, Tassios P, Daikos G. Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensions. Clin Microbiol Rev. 2012;25:682-707 pubmed publisher
    ..Fortunately, there are sound studies showing successful containment of CPE by bundles of measures, among which the most important are active surveillance cultures, separation of carriers, and assignment of dedicated nursing staff. ..
  3. Joseph S, Cetinkaya E, Drahovska H, Levican A, Figueras M, Forsythe S. Cronobacter condimenti sp. nov., isolated from spiced meat, and Cronobacter universalis sp. nov., a species designation for Cronobacter sp. genomospecies 1, recovered from a leg infection, water and food ingredients. Int J Syst Evol Microbiol. 2012;62:1277-83 pubmed publisher
    ..DNA-DNA reassociation and phenotypic analysis confirmed that these strains represent a novel species, for which the name Cronobacter universalis sp. nov. is proposed (type strain NCTC 9529(T) = CECT 7864(T) = LMG 26249(T)). ..
  4. Lowe C, Katz K, Mcgeer A, Muller M. Disparity in infection control practices for multidrug-resistant Enterobacteriaceae. Am J Infect Control. 2012;40:836-9 pubmed publisher
    ..These results are concerning given evidence that a coordinated approach may be required to prevent or limit the emergence of CRE. ..
  5. Shoorashetty R, Nagarathnamma T, Prathibha J. Comparison of the boronic acid disk potentiation test and cefepime-clavulanic acid method for the detection of ESBL among AmpC-producing Enterobacteriaceae. Indian J Med Microbiol. 2011;29:297-301 pubmed publisher
    ..This method fails to detect ESBL in the presence of AmpC. Therefore, we compared two different ESBL detection methods against the CLSI confirmatory test...
  6. Wolcott R, Dowd S. Molecular diagnosis of Raoultella planticola infection of a surgical site. J Wound Care. 2010;19:329-32 pubmed
    ..This pathogen was diagnosed with rapid clinical molecular pathogen diagnostic methods, which allowed an appropriate therapy to be implemented, thereby improving prognosis. ..
  7. Rankin L, Groom J, Chopin M, Herold M, Walker J, Mielke L, et al. The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway. Nat Immunol. 2013;14:389-95 pubmed publisher
    ..Our results pinpoint the regulation of Notch signaling by T-bet as a distinct molecular pathway that guides the development of NKp46+ ILCs...
  8. Freeman J, McBride S, Nisbet M, Gamble G, Williamson D, Taylor S, et al. Bloodstream infection with extended-spectrum beta-lactamase-producing Enterobacteriaceae at a tertiary care hospital in New Zealand: risk factors and outcomes. Int J Infect Dis. 2012;16:e371-4 pubmed publisher
    ..Known colonization with ESBL-E is a strong risk factor for ESBL-E bacteremia, and colonization status should be taken into consideration when choosing empirical therapy. ..
  9. Liu Z, Zaki M, Vogel P, Gurung P, Finlay B, Deng W, et al. Role of inflammasomes in host defense against Citrobacter rodentium infection. J Biol Chem. 2012;287:16955-64 pubmed publisher
    ..Thus, production of IL-1? and IL-18 downstream of the Nlrp3 and Nlrc4 inflammasomes plays a critical role in host defense against enteric infections caused by C. rodentium...
  10. Woerther P, Angebault C, Jacquier H, Hugede H, Janssens A, Sayadi S, et al. Massive increase, spread, and exchange of extended spectrum ?-lactamase-encoding genes among intestinal Enterobacteriaceae in hospitalized children with severe acute malnutrition in Niger. Clin Infect Dis. 2011;53:677-85 pubmed publisher
    ..Although their dissemination appears linked to Escherichia coli intestinal carriage, precise paths of this dynamic are largely unknown...
  11. Ota N, Wong K, Valdez P, Zheng Y, Crellin N, Diehl L, et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol. 2011;12:941-8 pubmed publisher
    ..rodentium in mice lacking lymphotoxin signals, which suggests that IL-22 connects the lymphotoxin pathway to mucosal epithelial defense mechanisms...
  12. Mathers A, Cox H, Kitchel B, Bonatti H, Brassinga A, Carroll J, et al. Molecular dissection of an outbreak of carbapenem-resistant enterobacteriaceae reveals Intergenus KPC carbapenemase transmission through a promiscuous plasmid. MBio. 2011;2:e00204-11 pubmed publisher
    ..Whether infection control measures that focus on preventing transmission of drug-resistant clones are effective in controlling dissemination of these elements is unknown. ..
  13. Hu F, Chen S, Xu X, Guo Y, Liu Y, Zhu D, et al. Emergence of carbapenem-resistant clinical Enterobacteriaceae isolates from a teaching hospital in Shanghai, China. J Med Microbiol. 2012;61:132-6 pubmed publisher
  14. Basu R, O Quinn D, Silberger D, Schoeb T, Fouser L, Ouyang W, et al. Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria. Immunity. 2012;37:1061-75 pubmed publisher
    ..These findings establish Th22 cells as an important component of mucosal antimicrobial host defense. ..
  15. Nordmann P, Poirel L, Dortet L. Rapid detection of carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis. 2012;18:1503-7 pubmed publisher
    ..It was 100% sensitive and specific compared with molecular-based techniques. This rapid (<2 hours), inexpensive technique may be implemented in any laboratory. ..
  16. Kim Y, Kamada N, Shaw M, Warner N, Chen G, Franchi L, et al. The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes. Immunity. 2011;34:769-80 pubmed publisher
    ..Thus, Nod2 mediates CCL2-CCR2-dependent recruitment of inflammatory monocytes, which is important in promoting bacterial eradication in the intestine...
  17. Petty N, Feltwell T, Pickard D, Clare S, Toribio A, Fookes M, et al. Citrobacter rodentium is an unstable pathogen showing evidence of significant genomic flux. PLoS Pathog. 2011;7:e1002018 pubmed publisher
    ..We draw parallels with the evolution of other bacterial pathogens and conclude that C. rodentium is a recently evolved pathogen that may have emerged alongside the development of inbred mice as a model for human disease. ..
  18. Short S, Wolfner M, Lazzaro B. Female Drosophila melanogaster suffer reduced defense against infection due to seminal fluid components. J Insect Physiol. 2012;58:1192-201 pubmed publisher
  19. van der Bij A, Pitout J. The role of international travel in the worldwide spread of multiresistant Enterobacteriaceae. J Antimicrob Chemother. 2012;67:2090-100 pubmed publisher
    ..The emergence of CTX-M-, KPC- and NDM-producing bacteria is a good example of the role that globalization plays in the rapid dissemination of new antibiotic resistance mechanisms. ..
  20. Gurung P, Malireddi R, Anand P, Demon D, Vande Walle L, Liu Z, et al. Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-? (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens. J Biol Chem. 2012;287:34474-83 pubmed publisher
    ..typhimurium. Thus, TLR4- and TRIF-induced caspase-11 synthesis is critical for noncanonical Nlrp3 inflammasome activation in macrophages infected with enteric pathogens. ..
  21. Williamson D, Sidjabat H, Freeman J, Roberts S, Silvey A, Woodhouse R, et al. Identification and molecular characterisation of New Delhi metallo-?-lactamase-1 (NDM-1)- and NDM-6-producing Enterobacteriaceae from New Zealand hospitals. Int J Antimicrob Agents. 2012;39:529-33 pubmed publisher
  22. Li C, Zhang Y, Wang R, Lu J, Nandi S, Mohanty S, et al. RNA-seq analysis of mucosal immune responses reveals signatures of intestinal barrier disruption and pathogen entry following Edwardsiella ictaluri infection in channel catfish, Ictalurus punctatus. Fish Shellfish Immunol. 2012;32:816-27 pubmed publisher
    ..Understanding of molecular mechanisms of pathogen entry during infection will provide insight into strategies for selection of resistant catfish brood stocks against various diseases...
  23. Day K, Ali S, Mirza I, Sidjabat H, Silvey A, Lanyon C, et al. Prevalence and molecular characterization of Enterobacteriaceae producing NDM-1 carbapenemase at a military hospital in Pakistan and evaluation of two chromogenic media. Diagn Microbiol Infect Dis. 2013;75:187-91 pubmed publisher
    ..NDM-1 carbapenemase was most commonly found amongst commensal types of Escherichia coli, especially phylogenetic group B1...
  24. Xu L, Shabir S, Bodah T, McMurray C, Hardy K, Hawkey P, et al. Regional survey of CTX-M-type extended-spectrum ?-lactamases among Enterobacteriaceae reveals marked heterogeneity in the distribution of the ST131 clone. J Antimicrob Chemother. 2011;66:505-11 pubmed publisher
    ..To establish the prevalence and diversity of clinically significant extended-spectrum ?-lactamase (ESBL)-producing Enterobacteriaceae harbouring bla(CTX-M) in the West Midlands region of the UK...
  25. Wine E, Shen Tu G, Gareau M, Goldberg H, Licht C, Ngan B, et al. Osteopontin mediates Citrobacter rodentium-induced colonic epithelial cell hyperplasia and attaching-effacing lesions. Am J Pathol. 2010;177:1320-32 pubmed publisher
    ..rodentium infection, indicating that OPN impacts disease pathogenesis through bacterial attachment and altered host immune responses...
  26. Millán B, Ghiglione B, Díaz T, Gutkind G, Araque M. CTX-M-14 ?-lactamase-producing Citrobacter freundii isolated in Venezuela. Ann Clin Microbiol Antimicrob. 2011;10:22 pubmed publisher
    ..freundii.LM07/10. Although this is the first report of CTX-M-14 in Venezuela, we alert the medical community that future increase of these ?-lactamases in our city could be due to dissemination of plasmids into bacterial populations...
  27. Golub V, Kim A, Krol V. Surgical wound infection, tuboovarian abscess, and sepsis caused by Edwardsiella tarda: case reports and literature review. Infection. 2010;38:487-9 pubmed publisher
    ..tarda infection and cholangitis who recently traveled to Ecuador. He presented with hypoxia and further workup revealed choledocholithiasis and common bile duct benign polyps. Both patients made a full recovery...
  28. Sun Y, Liu C, Sun L. Comparative study of the immune effect of an Edwardsiella tarda antigen in two forms: subunit vaccine vs DNA vaccine. Vaccine. 2011;29:2051-7 pubmed publisher
    ..Taken together, these results indicate that both rEta2 and pCEta2 induce specific and nonspecific immunities, however, pCEta2 induces both B cell and T cell responses, whereas rEta2 induces mainly humoral response...
  29. Ku K, Pogue J, Moshos J, Bheemreddy S, Wang Y, Bhargava A, et al. Retrospective evaluation of colistin versus tigecycline for the treatment of Acinetobacter baumannii and/or carbapenem-resistant Enterobacteriaceae infections. Am J Infect Control. 2012;40:983-7 pubmed publisher
    ..Study aim was to compare the efficacy of colistin to tigecycline for the treatment of these types of infections...
  30. Kawai T, Kusakabe H, Seki A, Kobayashi S, Onodera M. Osteomyelitis due to trimethoprim/sulfamethoxazole-resistant Edwardsiella tarda infection in a patient with X-linked chronic granulomatous disease. Infection. 2011;39:171-3 pubmed publisher
    ..tarda in a patient with chronic granulomatous disease (CGD). Once E. tarda acquires antibiotic resistance, infected CGD patients may develop severe infections with unforeseeable consequences...
  31. Kiss E, Vonarbourg C, Kopfmann S, Hobeika E, Finke D, Esser C, et al. Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles. Science. 2011;334:1561-5 pubmed publisher
    ..Our results establish a molecular link between nutrients and the formation of immune system components required to maintain intestinal homeostasis and resistance to infections...
  32. Wang Y, Wang Q, Xiao J, Liu Q, Wu H, Zhang Y. Genetic relationships of Edwardsiella strains isolated in China aquaculture revealed by rep-PCR genomic fingerprinting and investigation of Edwardsiella virulence genes. J Appl Microbiol. 2011;111:1337-48 pubmed publisher
    ..The aim of this study was to classify Edwardsiella strains isolated from China aquaculture based on biochemical and molecular methods...
  33. Huang T, Bogaerts P, Berhin C, Guisset A, Glupczynski Y. Evaluation of Brilliance ESBL agar, a novel chromogenic medium for detection of extended-spectrum-beta- lactamase-producing Enterobacteriaceae. J Clin Microbiol. 2010;48:2091-6 pubmed publisher
    ..The high negative predictive value (99.3%) found for OX suggests that this medium may constitute an excellent screening tool for the rapid exclusion of patients not carrying ESBL producers...
  34. Perry J, Naqvi S, Mirza I, Alizai S, Hussain A, Ghirardi S, et al. Prevalence of faecal carriage of Enterobacteriaceae with NDM-1 carbapenemase at military hospitals in Pakistan, and evaluation of two chromogenic media. J Antimicrob Chemother. 2011;66:2288-94 pubmed publisher
  35. Fernandez A, Pereira M, Suárez J, Poza M, Treviño M, Villalón P, et al. Emergence in Spain of a multidrug-resistant Enterobacter cloacae clinical isolate producing SFO-1 extended-spectrum beta-lactamase. J Clin Microbiol. 2011;49:822-8 pubmed publisher
    ..This study describes for the first time an outbreak in which an SFO-1-producing E. cloacae strain was involved. Note that so far, this ?-lactamase has previously been isolated in only a single case of E. cloacae infection in Japan...
  36. Gomez S, Rapoport M, Togneri A, Viegas Caetano J, Faccone D, Corso A, et al. Emergence of metallo-?-lactamases in Enterobacteriaceae from Argentina. Diagn Microbiol Infect Dis. 2011;69:94-7 pubmed publisher
    ..ESBL bla(PER-2) was detected in both strains and M9921 also harboured qnrB10, aac(6')-Ib and aac(6')-Ib-cr. This is the first report of MBLs in Enterobacteriaceae from Argentina...
  37. Cuevas O, Cercenado E, Gimeno M, Marin M, Coronel P, Bouza E. Comparative in vitro activity of cefditoren and other antimicrobials against Enterobacteriaceae causing community-acquired uncomplicated urinary tract infections in women: a Spanish nationwide multicenter study. Diagn Microbiol Infect Dis. 2010;67:251-60 pubmed publisher
    ..2%, 5.5%, 2.3%, 20.2%, 27.4%, and 4.8%. The activity of cefditoren against Enterobacteriaceae producing community-acquired uncomplicated UTI in women was superior to that of AMP, A/C, FUR, CIP, and SxT and similar to that of FOS...
  38. Galani I, Souli M, Panagea T, Poulakou G, Kanellakopoulou K, Giamarellou H. Prevalence of 16S rRNA methylase genes in Enterobacteriaceae isolates from a Greek university hospital. Clin Microbiol Infect. 2012;18:E52-4 pubmed publisher
    ..All rmtB-harbouring isolates were clonally unrelated. None of the E. coli (n = 1398) and Enterobacter spp. (n = 414) isolates were positive for armA, rmtA, rmtB, rmtC or rmtD...
  39. Poirel L, Potron A, Nordmann P. OXA-48-like carbapenemases: the phantom menace. J Antimicrob Chemother. 2012;67:1597-606 pubmed publisher
    ..Adequate screening and detection methods are therefore required to prevent and control their dissemination...
  40. Qiu J, Heller J, Guo X, Chen Z, Fish K, Fu Y, et al. The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells. Immunity. 2012;36:92-104 pubmed publisher
    ..Our data uncover a previously unrecognized physiological role for Ahr in promoting innate gut immunity by regulating ROR?t(+) ILCs. ..
  41. Tumanov A, Koroleva E, Guo X, Wang Y, Kruglov A, Nedospasov S, et al. Lymphotoxin controls the IL-22 protection pathway in gut innate lymphoid cells during mucosal pathogen challenge. Cell Host Microbe. 2011;10:44-53 pubmed publisher
    ..Taken together, our data show that LT?R signaling in gut lymphoid follicles regulates IL-22 production by ILCs in response to mucosal pathogen challenge...
  42. Overdevest I, Willemsen I, Rijnsburger M, Eustace A, Xu L, Hawkey P, et al. Extended-spectrum ?-lactamase genes of Escherichia coli in chicken meat and humans, The Netherlands. Emerg Infect Dis. 2011;17:1216-22 pubmed publisher
    ..These findings suggest that the abundant presence of ESBL genes in the food chain may have a profound effect on future treatment options for a wide range of infections caused by gram-negative bacteria...
  43. Cohen Stuart J, Dierikx C, al Naiemi N, Karczmarek A, Van Hoek A, Vos P, et al. Rapid detection of TEM, SHV and CTX-M extended-spectrum beta-lactamases in Enterobacteriaceae using ligation-mediated amplification with microarray analysis. J Antimicrob Chemother. 2010;65:1377-81 pubmed publisher
    ..The aim of this study was to develop and evaluate a novel ESBL assay using ligation-mediated amplification combined with microarray analysis to detect the most prevalent ESBLs in Enterobacteriaceae: TEM, SHV and CTX-M...
  44. Xu L, Wang Q, Xiao J, Liu Q, Wang X, Chen T, et al. Characterization of Edwardsiella tarda waaL: roles in lipopolysaccharide biosynthesis, stress adaptation, and virulence toward fish. Arch Microbiol. 2010;192:1039-47 pubmed publisher
    ..tarda, signifying the gene as a potential target for live attenuated vaccine against this bacterium...
  45. Goddard S, Muller M. The efficacy of infection control interventions in reducing the incidence of extended-spectrum ?-lactamase-producing Enterobacteriaceae in the nonoutbreak setting: A systematic review. Am J Infect Control. 2011;39:599-601 pubmed publisher
    ..Although 4 uncontrolled, retrospective studies were included in the review, no well designed prospective studies capable of informing infection control practice were identified, underscoring the urgent need for research in this area...
  46. Castro N, Toranzo A, Bastardo A, Barja J, Magariños B. Intraspecific genetic variability of Edwardsiella tarda strains from cultured turbot. Dis Aquat Organ. 2011;95:253-8 pubmed publisher
  47. Sonnenberg G, Monticelli L, Elloso M, Fouser L, Artis D. CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut. Immunity. 2011;34:122-34 pubmed publisher
    ..Collectively these data demonstrate that adult CD4(+) LTi cells are a critical source of IL-22 and identify a previously unrecognized function for CD4(+) LTi cells in promoting innate immunity in the intestine. ..
  48. Sun Y, Liu C, Sun L. Identification of an Edwardsiella tarda surface antigen and analysis of its immunoprotective potential as a purified recombinant subunit vaccine and a surface-anchored subunit vaccine expressed by a fish commensal strain. Vaccine. 2010;28:6603-8 pubmed publisher
    ..Together these results indicate that Esa1 is a protective immunogen and an effective oral vaccine when delivered by FP3/pJsa1 as a surface-anchored antigen...
  49. Doyle D, Peirano G, Lascols C, Lloyd T, Church D, Pitout J. Laboratory detection of Enterobacteriaceae that produce carbapenemases. J Clin Microbiol. 2012;50:3877-80 pubmed publisher
    ..MHT and MBL Etest were often difficult to interpret. We recommend using molecular tests for the optimal detection of carbapenemase-producing Enterobacteriaceae...
  50. Wlodarska M, Willing B, Keeney K, Menendez A, Bergstrom K, Gill N, et al. Antibiotic treatment alters the colonic mucus layer and predisposes the host to exacerbated Citrobacter rodentium-induced colitis. Infect Immun. 2011;79:1536-45 pubmed publisher
    ..These results suggest that antibiotic perturbation of the microbiota can disrupt intestinal homeostasis and the integrity of intestinal defenses, which protect against invading pathogens and intestinal inflammation...
  51. Lonchel C, Meex C, Gangoue Pieboji J, Boreux R, Assoumou M, Melin P, et al. Proportion of extended-spectrum ß-lactamase-producing Enterobacteriaceae in community setting in Ngaoundere, Cameroon. BMC Infect Dis. 2012;12:53 pubmed publisher
    ..The current study aimed to determine the proportion of ESBLs in Enterobacteriaceae isolated in the community and to analyse some risk factors associated with ESBL carriage...
  52. Dierikx C, van Duijkeren E, Schoormans A, van Essen Zandbergen A, Veldman K, Kant A, et al. Occurrence and characteristics of extended-spectrum-?-lactamase- and AmpC-producing clinical isolates derived from companion animals and horses. J Antimicrob Chemother. 2012;67:1368-74 pubmed publisher
  53. Gupta N, Limbago B, Patel J, Kallen A. Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. Clin Infect Dis. 2011;53:60-7 pubmed publisher
    ..As a result, preventing both CRE transmission and CRE infections have become important public health objectives. This review describes the current epidemiology of CRE in the United States and highlights important prevention strategies...
  54. Casellas J. [Antibacterial drug resistance in Latin America: consequences for infectious disease control]. Rev Panam Salud Publica. 2011;30:519-28 pubmed
    ..The same cannot be said for infections caused by enterobacteria and nonfermenting gram-negative bacilli, where options for the effective treatment of patients are still insufficient...
  55. Maiti B, Shetty M, Shekar M, Karunasagar I, Karunasagar I. Recombinant outer membrane protein A (OmpA) of Edwardsiella tarda, a potential vaccine candidate for fish, common carp. Microbiol Res. 2011;167:1-7 pubmed publisher
    ..Common carp vaccinated with recombinant OmpA protein elicited high antibody production and immunized fish showed a relative percentage survival of 54.3 on challenge...
  56. Adler A, Navon Venezia S, Moran Gilad J, Marcos E, Schwartz D, Carmeli Y. Laboratory and clinical evaluation of screening agar plates for detection of carbapenem-resistant Enterobacteriaceae from surveillance rectal swabs. J Clin Microbiol. 2011;49:2239-42 pubmed publisher
    ..However, MacI was the most specific method. In conclusion, MacI appears to be most appropriate medium for the detection of CRE in settings in which multiclonal CRE strains with various MICs to carbapenems are circulating...
  57. Rodrigues D, Sousa A, Johnson Henry K, Sherman P, Gareau M. Probiotics are effective for the prevention and treatment of Citrobacter rodentium-induced colitis in mice. J Infect Dis. 2012;206:99-109 pubmed publisher
    ..Probiotics prevent disease induced by Citrobacter rodentium, a murine-specific enteric pathogen. Whether probiotics can be used to interrupt the infectious process following initiation of infection was determined...
  58. Bergstrom K, Kissoon Singh V, Gibson D, Ma C, Montero M, Sham H, et al. Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PLoS Pathog. 2010;6:e1000902 pubmed publisher
    ..Such actions limit tissue damage and translocation of pathogenic and commensal bacteria across the epithelium...
  59. Brown J, Cheresh P, Goretsky T, Managlia E, Grimm G, Ryu H, et al. Epithelial phosphatidylinositol-3-kinase signaling is required for ?-catenin activation and host defense against Citrobacter rodentium infection. Infect Immun. 2011;79:1863-72 pubmed publisher
    ..The results suggest that the host defense against C. rodentium requires epithelial PI3K activation to induce Akt-mediated ?-catenin signaling and the clearance of C. rodentium independent of adaptive immune responses...
  60. Tsakris A, Poulou A, Pournaras S, Voulgari E, Vrioni G, Themeli Digalaki K, et al. A simple phenotypic method for the differentiation of metallo-beta-lactamases and class A KPC carbapenemases in Enterobacteriaceae clinical isolates. J Antimicrob Chemother. 2010;65:1664-71 pubmed publisher
    ..The increasing frequency of class A KPC enzymes and class B metallo-beta-lactamases (MBLs) among Enterobacteriaceae as well as their possible co-production makes their early differentiation urgent...
  61. Kamada N, Kim Y, Sham H, Vallance B, Puente J, Martens E, et al. Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science. 2012;336:1325-9 pubmed publisher
    ..Thus, pathogen colonization is controlled by bacterial virulence and through competition with metabolically related commensals...
  62. Castro N, Toranzo A, Nunez S, Osorio C, Magariños B. Evaluation of four polymerase chain reaction primer pairs for the detection of Edwardsiella tarda in turbot. Dis Aquat Organ. 2010;90:55-61 pubmed publisher
    ..tarda in the field, and, based on the findings, we propose it as the most appropriate for accurate detection of E. tarda in routine diagnosis of edwardsiellosis in fish...
  63. Manta C, Heupel E, Radulovic K, Rossini V, Garbi N, Riedel C, et al. CX(3)CR1(+) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium. Mucosal Immunol. 2013;6:177-88 pubmed publisher
    ..The depletion of CX(3)CR1(+) cells by diphtheria toxin injection in CX(3)CR1-GFP × CD11c.DOG animals confirmed the role of CX(3)CR1(+) phagocytes in establishing IL-22 production, supporting the clearance of a C. rodentium infection...
  64. Sham H, Shames S, Croxen M, Ma C, Chan J, Khan M, et al. Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-?B and p38 mitogen-activated protein kinase activation. Infect Immun. 2011;79:3552-62 pubmed publisher
    ..rodentium in a cecal loop model induced significantly greater chemokine responses than infection with wild-type bacteria. These studies thus advance our understanding of how A/E pathogens subvert host inflammatory responses...
  65. Deshpande P, Rodrigues C, Shetty A, Kapadia F, Hedge A, Soman R. New Delhi Metallo-beta lactamase (NDM-1) in Enterobacteriaceae: treatment options with carbapenems compromised. J Assoc Physicians India. 2010;58:147-9 pubmed
    ..Many of them were recently hospitalized in India and Pakistan and had new type of metallo beta lactamase designated as New Delhi Metallo-1 (NDM-1)...
  66. van Soest J, Stockhammer O, Ordas A, Bloemberg G, Spaink H, Meijer A. Comparison of static immersion and intravenous injection systems for exposure of zebrafish embryos to the natural pathogen Edwardsiella tarda. BMC Immunol. 2011;12:58 pubmed publisher
    ..In this study we used transcriptome profiling and quantitative RT-PCR to analyze the immune response induced by E. tarda immersion and injection...
  67. Paniagua R, Valverde A, Coque T, Baquero F, Canton R. Assessment of prevalence and changing epidemiology of extended-spectrum beta-lactamase-producing Enterobacteriaceae fecal carriers using a chromogenic medium. Diagn Microbiol Infect Dis. 2010;67:376-9 pubmed publisher
    ..The chromID ESBL medium was reliable to screen ESBL fecal carriers with a general decrease in the laboratory workload. Time-to-time monitoring of ESBL fecal carriers is useful to ascertain current trend of ESBL epidemiology...
  68. Dahmen S, Bettaieb D, Mansour W, Boujaafar N, Bouallegue O, Arlet G. Characterization and molecular epidemiology of extended-spectrum beta-lactamases in clinical isolates of Enterobacteriaceae in a Tunisian University Hospital. Microb Drug Resist. 2010;16:163-70 pubmed publisher
    ..This study confirms the high rate of ESBLs in Tunisia and further demonstrates the worldwide spread of genes coding for CTX-M-15 enzymes in clinical isolates...
  69. Chandrakesan P, Ahmed I, Anwar T, Wang Y, Sarkar S, Singh P, et al. Novel changes in NF-{kappa}B activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38. J Biol Chem. 2010;285:33485-98 pubmed publisher
    ..The MEK/ERK/p38 pathway therefore seems to modulate sustained activation of NF-?B in colonic crypts in response to C. rodentium infection. ..
  70. Wang X, Wang Q, Xiao J, Liu Q, Wu H, Zhang Y. Hemolysin EthA in Edwardsiella tarda is essential for fish invasion in vivo and in vitro and regulated by two-component system EsrA-EsrB and nucleoid protein HhaEt. Fish Shellfish Immunol. 2010;29:1082-91 pubmed publisher
    ..tarda and was subjected to the control of a complicated and precisely regulated network primed for its invasion, colonization and infection process in fish...
  71. Manoharan A, Premalatha K, Chatterjee S, Mathai D. Correlation of TEM, SHV and CTX-M extended-spectrum beta lactamases among Enterobacteriaceae with their in vitro antimicrobial susceptibility. Indian J Med Microbiol. 2011;29:161-4 pubmed publisher
    ..The present study was carried out to characterize the ESBL types and evaluated their in vitro activity against a collection of Gram negative bacteria (GNB) from a multicentric Indian surveillance study...
  72. Menanteau Ledouble S, Karsi A, Lawrence M. Importance of skin abrasion as a primary site of adhesion for Edwardsiella ictaluri and impact on invasion and systematic infection in channel catfish Ictalurus punctatus. Vet Microbiol. 2011;148:425-30 pubmed publisher
    ..This study constitutes the first report on the role of channel catfish skin as a portal of entry for E. ictaluri and further illustrates how versatile this pathogen can be in its mechanisms of entry...
  73. Nordmann P, Poirel L, Carrër A, Toleman M, Walsh T. How to detect NDM-1 producers. J Clin Microbiol. 2011;49:718-21 pubmed publisher
    ..Colonies growing on these screening media can be verified as NDM-1 producers with molecular methods as described herein...
  74. Nordmann P, Gniadkowski M, Giske C, Poirel L, Woodford N, Miriagou V. Identification and screening of carbapenemase-producing Enterobacteriaceae. Clin Microbiol Infect. 2012;18:432-8 pubmed publisher
    ..Phenotypic and molecular-based techniques are able to identify these carbapenemase producers, although with variable efficiencies. The detection of carriers still relies mostly on the use of screening culture media...
  75. Razazi K, Derde L, Verachten M, Legrand P, Lesprit P, Brun Buisson C. Clinical impact and risk factors for colonization with extended-spectrum ?-lactamase-producing bacteria in the intensive care unit. Intensive Care Med. 2012;38:1769-78 pubmed publisher
  76. Livermore D, Mushtaq S, Warner M, Zhang J, Maharjan S, Doumith M, et al. Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates. J Antimicrob Chemother. 2011;66:48-53 pubmed publisher
    ..They included 53 Klebsiella spp., 19 Enterobacter spp., 6 Escherichia coli and 4 others; most were multiresistant. Genes were identified by PCR and sequencing; MICs were measured by CLSI agar dilution...
  77. Jiao X, Hu Y, Sun L. Dissection and localization of the immunostimulating domain of Edwardsiella tarda FliC. Vaccine. 2010;28:5635-40 pubmed publisher
    ..These results indicate that N163 is the immunodominant region of FliC and suggest that E. tarda FliC may induce immune responses in Japanese flounder via mechanisms alternative to that involving TLR5...
  78. Park S, Jang H, Nho S, Cha I, Hikima J, Ohtani M, et al. Outer membrane vesicles as a candidate vaccine against edwardsiellosis. PLoS ONE. 2011;6:e17629 pubmed publisher
    ..0001) than were control fish. Investigation of OMVs may be useful not only for understanding the pathogenesis of E. tarda but also in development of an effective vaccine against edwardsiellosis...
  79. Villegas M, Blanco M, Sifuentes Osornio J, Rossi F. Increasing prevalence of extended-spectrum-beta-lactamase among Gram-negative bacilli in Latin America--2008 update from the Study for Monitoring Antimicrobial Resistance Trends (SMART). Braz J Infect Dis. 2011;15:34-9 pubmed
    ..This analysis of the Study for Monitoring Antimicrobial Resistance Trends (SMART) evaluated the susceptibility patterns of Enterobacteriaceae in Latin America in 2008, with emphasis on susceptibility trends of E. coli and K. pneumoniae...
  80. Geser N, Stephan R, Hachler H. Occurrence and characteristics of extended-spectrum ?-lactamase (ESBL) producing Enterobacteriaceae in food producing animals, minced meat and raw milk. BMC Vet Res. 2012;8:21 pubmed publisher
    ..Additionally, 100 raw milk samples, representing bulk tank milk of 100 different dairy farms, 104 minced meat (pork and beef) samples and 67 E. coli isolates from cattle E. coli mastitis were analyzed...