whooping cough

Summary

Summary: A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath.

Top Publications

  1. Locht C, Mielcarek N. New pertussis vaccination approaches: en route to protect newborns?. FEMS Immunol Med Microbiol. 2012;66:121-33 pubmed publisher
    Pertussis or whooping cough is a life-threatening childhood disease, particularly severe during the first months of life, although adolescent and adult pertussis is increasingly more noted...
  2. Nilsson L, Lepp T, von Segebaden K, Hallander H, Gustafsson L. Pertussis vaccination in infancy lowers the incidence of pertussis disease and the rate of hospitalisation after one and two doses: analyses of 10 years of pertussis surveillance. Vaccine. 2012;30:3239-47 pubmed publisher
    ..Vaccine coverage, the timeliness of childhood vaccination and the effect of later than scheduled pertussis vaccination(s) are also examined...
  3. Campbell P, McIntyre P, Quinn H, Hueston L, Gilbert G, McVernon J. Increased population prevalence of low pertussis toxin antibody levels in young children preceding a record pertussis epidemic in Australia. PLoS ONE. 2012;7:e35874 pubmed publisher
    ..Our novel findings suggest that increased prevalence of undetectable IgG-PT is an indicator of waning immunity useful for population level monitoring following introduction of acellular vaccines and/or schedule changes. ..
  4. Bottero D, Griffith M, Lara C, Flores D, Pianciola L, Gaillard M, et al. Bordetella holmesii in children suspected of pertussis in Argentina. Epidemiol Infect. 2013;141:714-7 pubmed publisher
    ..Most patients reported cough and cold symptoms. No death was reported. We report B. holmesii isolation in infants with respiratory symptoms in Argentina...
  5. Fabricius G, Bergero P, Ormazabal M, Maltz A, Hozbor D. Modelling pertussis transmission to evaluate the effectiveness of an adolescent booster in Argentina. Epidemiol Infect. 2013;141:718-34 pubmed publisher
    ..An effort to improve the coverage of the first dose would have a much greater impact on infants. These results hold in the 18 scenarios considered, which demonstrates the robustness of these conclusions...
  6. Fisman D, Tang P, Hauck T, Richardson S, Drews S, Low D, et al. Pertussis resurgence in Toronto, Canada: a population-based study including test-incidence feedback modeling. BMC Public Health. 2011;11:694 pubmed publisher
    ..We evaluated pertussis trends in Toronto using all available specimen data, which allowed us to control for changing testing patterns and practices...
  7. Kamiya H, Otsuka N, Ando Y, Odaira F, Yoshino S, Kawano K, et al. Transmission of Bordetella holmesii during pertussis outbreak, Japan. Emerg Infect Dis. 2012;18:1166-9 pubmed publisher
    ..Six patients were infected; 4 patients were students and a teacher at the same junior high school. Epidemiologic links were found between 5 patients. B. holmesii may have been transmitted from person to person...
  8. Mooi F, van der Maas N, de Melker H. Pertussis resurgence: waning immunity and pathogen adaptation - two sides of the same coin. Epidemiol Infect. 2014;142:685-94 pubmed publisher
    Pertussis or whooping cough has persisted and resurged in the face of vaccination and has become one of the most prevalent vaccine-preventable diseases in Western countries...
  9. Paisley R, Blaylock J, Hartzell J. Whooping cough in adults: an update on a reemerging infection. Am J Med. 2012;125:141-3 pubmed publisher
    Pertussis, or whooping cough, which is commonly thought of as a pediatric illness, is an underappreciated adult pathogen...

More Information

Publications73

  1. Rohani P, Drake J. The decline and resurgence of pertussis in the US. Epidemics. 2011;3:183-8 pubmed publisher
  2. Kallonen T, Gröndahl Yli Hannuksela K, Elomaa A, Lutynska A, Fry N, Mertsola J, et al. Differences in the genomic content of Bordetella pertussis isolates before and after introduction of pertussis vaccines in four European countries. Infect Genet Evol. 2011;11:2034-42 pubmed publisher
    ..pertussis population with time, difference in frequency of the lost genes were observed among isolates from the four countries. The observed differences in genomic content might be vaccine-driven...
  3. Octavia S, Sintchenko V, Gilbert G, Lawrence A, Keil A, Hogg G, et al. Newly emerging clones of Bordetella pertussis carrying prn2 and ptxP3 alleles implicated in Australian pertussis epidemic in 2008-2010. J Infect Dis. 2012;205:1220-4 pubmed publisher
    ..The data suggest increasing selection among the B. pertussis population in Australia in favor of strains carrying prn2 and ptxP3 under the pressure of acellular vaccine-induced immunity...
  4. Quinn H, McIntyre P. The impact of adolescent pertussis immunization, 2004-2009: lessons from Australia. Bull World Health Organ. 2011;89:666-74 pubmed publisher
  5. Zhang S, Xu Y, Zhou Z, Wang S, Yang R, Wang J, et al. Complete genome sequence of Bordetella pertussis CS, a Chinese pertussis vaccine strain. J Bacteriol. 2011;193:4017-8 pubmed publisher
    ..Here, we report the genome sequence of Bordetella pertussis strain CS, isolated from an infant patient in Beijing and widely used as a vaccine strain for production of an acellular pertussis vaccine in China...
  6. Liu B, McIntyre P, Kaldor J, Quinn H, Ridda I, Banks E. Pertussis in older adults: prospective study of risk factors and morbidity. Clin Infect Dis. 2012;55:1450-6 pubmed publisher
    ..There is limited information on the incidence, morbidity and risk factors for pertussis in adults, particularly those aged over 65 years...
  7. Gall S. Prevention of pertussis, tetanus, and diphtheria among pregnant, postpartum women, and infants. Clin Obstet Gynecol. 2012;55:498-509 pubmed publisher
    ..Tdap is highly immunogenetic in the pregnant women and has an excellent safety profile. Tdap given to the postpartum patient and her cocoon family is an alternative strategy...
  8. Gabutti G, Rota M, Bonato B, Pirani R, Turlà G, Cucchi A, et al. Hospitalizations for pertussis in Italy, 1999-2009: analysis of the hospital discharge database. Eur J Pediatr. 2012;171:1651-5 pubmed publisher
    ..Conclusion These data, even if restricted to hospitalizations registered at national level, confirm the epidemiological impact of pertussis and its complications in a country with a consistently high vaccination coverage rate...
  9. Schmidtke A, Boney K, Martin S, Skoff T, Tondella M, Tatti K. Population diversity among Bordetella pertussis isolates, United States, 1935-2009. Emerg Infect Dis. 2012;18:1248-55 pubmed publisher
    ..Changes in the vaccine composition and schedule were not the direct selection pressures that resulted in the allele changes present in the current B. pertussis population...
  10. Tartof S, Lewis M, Kenyon C, White K, Osborn A, Liko J, et al. Waning immunity to pertussis following 5 doses of DTaP. Pediatrics. 2013;131:e1047-52 pubmed publisher
    ..To assess the risk of pertussis by time since vaccination in children in Minnesota and Oregon who received 5 doses of acellular pertussis vaccines (DTaP)...
  11. Shuel M, Jamieson F, Tang P, Brown S, Farrell D, Martin I, et al. Genetic analysis of Bordetella pertussis in Ontario, Canada reveals one predominant clone. Int J Infect Dis. 2013;17:e413-7 pubmed publisher
    ..To characterize Bordetella pertussis isolates in Ontario, Canada in order to understand the clonal diversity of strains present in this province...
  12. Rozenbaum M, De Cao E, Westra T, Postma M. Dynamic models for health economic assessments of pertussis vaccines: what goes around comes around. Expert Rev Vaccines. 2012;11:1415-28 pubmed publisher
    ..In future, dynamic transmission models for pertussis should be used widely to further enhance understanding of pertussis epidemiology and of extended pertussis vaccination programs that are currently considered in various countries...
  13. Hegerle N, Guiso N. Epidemiology of whooping cough & typing of Bordetella pertussis. Future Microbiol. 2013;8:1391-403 pubmed publisher
    ..It causes whooping cough or pertussis in humans, which is the most prevalent vaccine-preventable disease worldwide...
  14. Petersen R, Dalby T, Dragsted D, Mooi F, Lambertsen L. Temporal trends in Bordetella pertussis populations, Denmark, 1949-2010. Emerg Infect Dis. 2012;18:767-74 pubmed publisher
    ..These changes might have resulted from the introduction of pertussis vaccines in Denmark and other parts of Europe. The predominant strains currently circulating in Denmark resemble those in other European countries...
  15. Cornford Nairns R, Daggard G, Mukkur T. Construction and preliminary immunobiological characterization of a novel, non-reverting, intranasal live attenuated whooping cough vaccine candidate. J Microbiol Biotechnol. 2012;22:856-65 pubmed
    We describe the construction and immunobiological properties of a novel whooping cough vaccine candidate, in which the aroQ gene, encoding 3-dehydroquinase, was deleted by insertional inactivation using the kanamycin resistance gene ..
  16. Campins M, Moreno Perez D, Gil de Miguel A, González Romo F, Moraga Llop F, Arístegui Fernández J, et al. [Whooping cough in Spain. Current epidemiology, prevention and control strategies. Recommendations by the Pertussis Working Group]. Enferm Infecc Microbiol Clin. 2013;31:240-53 pubmed publisher
    ..Recently, pregnant women vaccination (after 20weeks of gestation) has been recommended in some countries as the most effective way to protect the newborn...
  17. Scott L, McCormack P. Reduced-antigen, combined diphtheria, tetanus, and acellular pertussis vaccine, adsorbed (boostrix(®)): a guide to its use as a single-dose booster immunization against pertussis. BioDrugs. 2013;27:75-81 pubmed publisher
    ..Tdap was safe and well tolerated in all age groups...
  18. Heininger U. Pertussis: what the pediatric infectious disease specialist should know. Pediatr Infect Dis J. 2012;31:78-9 pubmed publisher
    ..Control of pertussis by acellular vaccines is possible to some extent if immunization coverage is high and booster doses are given lifelong. However new vaccines with higher efficacy rates are warranted...
  19. Skoff T, Cohn A, Clark T, Messonnier N, Martin S. Early Impact of the US Tdap vaccination program on pertussis trends. Arch Pediatr Adolesc Med. 2012;166:344-9 pubmed publisher
    ..To evaluate the impact of the adolescent Tdap (tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine) vaccination program on pertussis trends in the United States...
  20. Hegerle N, Paris A, Brun D, Dore G, Njamkepo E, Guillot S, et al. Evolution of French Bordetella pertussis and Bordetella parapertussis isolates: increase of Bordetellae not expressing pertactin. Clin Microbiol Infect. 2012;18:E340-6 pubmed publisher
    Bordetella pertussis and Bordetella parapertussis are closely related bacterial agents of whooping cough. Whole-cell pertussis (wP) vaccine was introduced in France in 1959...
  21. Rozenbaum M, De Cao E, Postma M. Cost-effectiveness of pertussis booster vaccination in the Netherlands. Vaccine. 2012;30:7327-31 pubmed publisher
    ..To conclude, we show that extended pertussis booster vaccination strategies are likely to be considered as cost-effective...
  22. Rodgers L, Martin S, Cohn A, Budd J, Marcon M, Terranella A, et al. Epidemiologic and laboratory features of a large outbreak of pertussis-like illnesses associated with cocirculating Bordetella holmesii and Bordetella pertussis--Ohio, 2010-2011. Clin Infect Dis. 2013;56:322-31 pubmed publisher
    ..The majority of cases were identified by IS481-directed polymerase chain reaction (PCR), which does not differentiate among Bordetella species. We sought to determine outbreak etiology and epidemiologic characteristics...
  23. Leboucher B, Sentilhes L, Abbou F, Henry E, Grimprel E, Descamps P. Impact of postpartum information about pertussis booster to parents in a university maternity hospital. Vaccine. 2012;30:5472-81 pubmed publisher
    ..Postpartum information about pertussis was successfully implemented and well understood by parents in the maternity hospital and should contribute towards increasing pertussis vaccination coverage in parents of young children...
  24. van Gent M, Bart M, van der Heide H, Heuvelman K, Mooi F. Small mutations in Bordetella pertussis are associated with selective sweeps. PLoS ONE. 2012;7:e46407 pubmed publisher
    ..Further, this work shows that small mutations, even single SNPs, can drive large changes in the populations of bacterial pathogens within a time span of six to 19 years...
  25. Zhang Q, Han F, Nie Q, Ren H, Zhang B, Liu Q, et al. Seroprevalence of antibodies to pertussis and diphtheria among healthy adults in China. J Infect. 2011;63:441-6 pubmed publisher
    ..The aim of this study was to determine seroprevalence of IgG antibodies to pertussis toxin (PT) and diphtheria among adults in China...
  26. Miyashita N, Kawai Y, Yamaguchi T, Ouchi K. Evaluation of serological tests for diagnosis of Bordetella pertussis infection in adolescents and adults. Respirology. 2011;16:1189-95 pubmed publisher
    ..To determine the serological criteria, the comparative titres of bacterial agglutination antibody and anti-pertussis toxin (PT) antibody were evaluated...
  27. Garlapati S, Eng N, Kiros T, Kindrachuk J, Mutwiri G, Hancock R, et al. Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis. Vaccine. 2011;29:6540-8 pubmed publisher
  28. Winter K, Harriman K, Zipprich J, Schechter R, Talarico J, Watt J, et al. California pertussis epidemic, 2010. J Pediatr. 2012;161:1091-6 pubmed publisher
    ..This report provides a descriptive epidemiologic analysis of this epidemic and describes public health mitigation strategies that were used, including expanded pertussis vaccine recommendations...
  29. Ridda I, Yin J, King C, Raina Macintyre C, McIntyre P. The importance of pertussis in older adults: a growing case for reviewing vaccination strategy in the elderly. Vaccine. 2012;30:6745-52 pubmed publisher
    Pertussis or whooping cough is increasingly being shown to be a respiratory infection affecting the elderly and a significant percentage of older people infected with Bordetella pertussis experience considerable morbidity and even ..
  30. Klein N, Bartlett J, Rowhani Rahbar A, Fireman B, Baxter R. Waning protection after fifth dose of acellular pertussis vaccine in children. N Engl J Med. 2012;367:1012-9 pubmed publisher
    ..In the United States, children receive five doses of diphtheria, tetanus, and acellular pertussis (DTaP) vaccine before 7 years of age. The duration of protection after five doses of DTaP is unknown...
  31. Bechini A, Tiscione E, Boccalini S, Levi M, Bonanni P. Acellular pertussis vaccine use in risk groups (adolescents, pregnant women, newborns and health care workers): a review of evidences and recommendations. Vaccine. 2012;30:5179-90 pubmed publisher
    ..is an acute infectious illness, caused by the bacteria Bordetella pertussis and commonly known as "whooping cough"...
  32. Campbell H, Amirthalingam G, Andrews N, Fry N, George R, Harrison T, et al. Accelerating control of pertussis in England and Wales. Emerg Infect Dis. 2012;18:38-47 pubmed publisher
    ..e., <3 months of age), teenagers, and adults. Future vaccine program changes may be beneficial, but additional detail is required to inform such decisions...
  33. McCormack P. Reduced-antigen, combined diphtheria, tetanus and acellular pertussis vaccine, adsorbed (Boostrix®): a review of its properties and use as a single-dose booster immunization. Drugs. 2012;72:1765-91 pubmed publisher
  34. Tizolova A, Guiso N, Guillot S. Insertion sequences shared by Bordetella species and implications for the biological diagnosis of pertussis syndrome. Eur J Clin Microbiol Infect Dis. 2013;32:89-96 pubmed publisher
    ..Our results confirm that biological diagnosis targeting the IS481 and IS1001 elements are not specific and detect the species B. pertussis, B. holmesii and B. bronchiseptica (IS481), and B. parapertussis and B. bronchiseptica (IS1001)...
  35. Philipson K, Goodyear Smith F, Grant C, Chong A, Turner N, Stewart J. When is acute persistent cough in school-age children and adults whooping cough? A prospective case series study. Br J Gen Pract. 2013;63:e573-9 pubmed publisher
    ..Pertussis is a vaccine modified disease in most age groups and hence subtle in its presentation. Current diagnostic approaches require relatively invasive sampling...
  36. Prato R, Martinelli D, Marchetti F, Fortunato F, Tafuri S, Germinario C. Feasibility of a cocoon strategy for the prevention of pertussis in Italy: a survey of prevention department healthcare providers. Pediatr Infect Dis J. 2012;31:1304-7 pubmed publisher
    ..Prevention Departments should promote and coordinate locally the strategy in 75% of the respondents. Cocoon should be recommended by Regional Authority in 82% of the interviewees...
  37. Witt M, Katz P, Witt D. Unexpectedly limited durability of immunity following acellular pertussis vaccination in preadolescents in a North American outbreak. Clin Infect Dis. 2012;54:1730-5 pubmed publisher
    ..It has been suggested that acellular vaccine may be less effective than previously believed. During a large outbreak, we examined the incidence of pertussis and effectiveness of vaccination in a well-vaccinated, well-defined community...
  38. Zouari A, Smaoui H, Brun D, Njamkepo E, Sghaier S, Zouari E, et al. Prevalence of Bordetella pertussis and Bordetella parapertussis infections in Tunisian hospitalized infants: results of a 4-year prospective study. Diagn Microbiol Infect Dis. 2012;72:303-17 pubmed publisher
    ..Given this situation, sensitive and specific laboratory tests are needed to improve the accuracy of pertussis diagnosis...
  39. Cherry J, Tan T, Wirsing von Konig C, Forsyth K, Thisyakorn U, Greenberg D, et al. Clinical definitions of pertussis: Summary of a Global Pertussis Initiative roundtable meeting, February 2011. Clin Infect Dis. 2012;54:1756-64 pubmed publisher
    ..Determination of their utility and their sensitivity and/or specificity versus existing case definitions is required...
  40. Skowronski D, Janjua N, Tsafack E, Ouakki M, Hoang L, De Serres G. The number needed to vaccinate to prevent infant pertussis hospitalization and death through parent cocoon immunization. Clin Infect Dis. 2012;54:318-27 pubmed publisher
    ..We illustrate the high number needed to vaccinate (NNV) for this program based on recent epidemiologic data from the provinces of Québec and British Columbia (BC), Canada...
  41. Lavine J, Bjørnstad O, De Blasio B, Storsaeter J. Short-lived immunity against pertussis, age-specific routes of transmission, and the utility of a teenage booster vaccine. Vaccine. 2012;30:544-51 pubmed publisher
    ..We aim to assess the duration of vaccine-induced immunity, and the possibility for a teenage-booster vaccine to protect infants in Norway...
  42. Castagnini L, Healy C, Rench M, Wootton S, Munoz F, Baker C. Impact of maternal postpartum tetanus and diphtheria toxoids and acellular pertussis immunization on infant pertussis infection. Clin Infect Dis. 2012;54:78-84 pubmed publisher
    ..In January 2008, this recommendation was implemented in a predominantly Hispanic, medically underserved population at Ben Taub General Hospital (BTGH) in Houston (hereafter the intervention population)...
  43. Hendrikx L, de Rond L, Oztürk K, Veenhoven R, Sanders E, Berbers G, et al. Impact of infant and preschool pertussis vaccinations on memory B-cell responses in children at 4 years of age. Vaccine. 2011;29:5725-30 pubmed publisher
    b>Whooping cough, caused by Bordetella pertussis, is reemerging in the vaccinated population...
  44. Morrison W. Infantile hypertrophic pyloric stenosis in infants treated with azithromycin. Pediatr Infect Dis J. 2007;26:186-8 pubmed
    ..Two of the infants were subsequently diagnosed with hypertrophic pyloric stenosis and underwent surgical pyloromyotomies 6 and 7 weeks, respectively, after the initial admission. ..
  45. Lavine J, Broutin H, Harvill E, Bjørnstad O. Imperfect vaccine-induced immunity and whooping cough transmission to infants. Vaccine. 2010;29:11-6 pubmed publisher
    b>Whooping cough, caused by B. pertussis and B...
  46. Cooper N, Bricknell M, Holden G, McWilliam C. Pertussis -- a case finding study amongst returnees from Op Herrick. J R Army Med Corps. 2007;153:114-6 pubmed
    ..It is recommended that enhanced health surveillance for Pertussis takes place both during and after future deployments to Afghanistan, to prevent the potential onward transmission of a potentially fatal illness to unimmunised children. ..
  47. Wearing H, Rohani P. Estimating the duration of pertussis immunity using epidemiological signatures. PLoS Pathog. 2009;5:e1000647 pubmed publisher
    ..Our results support a period of natural immunity that is, on average, long-lasting (at least 30 years) but inherently variable...
  48. Baptista P, Magalhães V, Rodrigues L, Rocha M, Pimentel A. Pertussis vaccine effectiveness in reducing clinical disease, transmissibility and proportion of cases with a positive culture after household exposure in Brazil. Pediatr Infect Dis J. 2006;25:844-6 pubmed
    ..Three doses of pertussis vaccine are likely to decrease circulation of Bordetella pertussis by reducing the proportion of bacteriologically positive cases and transmissibility. ..
  49. von Linstow M, Pontoppidan P, von König C, Cherry J, Hogh B. Evidence of Bordetella pertussis infection in vaccinated 1-year-old Danish children. Eur J Pediatr. 2010;169:1119-22 pubmed publisher
    ..pertussis infection. A prospective immunization study comparing a multi-component vaccine with the present monocomponent PT toxoid vaccine should be undertaken. ..
  50. Okada K, Komiya T, Yamamoto A, Takahashi M, Kamachi K, Nakano T, et al. Safe and effective booster immunization using DTaP in teenagers. Vaccine. 2010;28:7626-33 pubmed publisher
    ..Instead of the scheduled DT program, 0.2 ml of DTaP was acceptable and demonstrated efficient immunogenicity. ..
  51. Knuf M, Schmitt H, Jacquet J, Collard A, Kieninger D, Meyer C, et al. Booster vaccination after neonatal priming with acellular pertussis vaccine. J Pediatr. 2010;156:675-8 pubmed publisher
    ..Thus, neonatal aP priming did not lead to immune tolerance to pertussis antigens. However, it elicited bystander interference on HBV, Hib, and diphtheria responses. ..
  52. Rendi Wagner P, Paulke Korinek M, Stanek G, Khanakah G, Kollaritsch H. Impact of a pertussis booster vaccination program in adolescents and adults on the epidemiology of pertussis in Austria. Pediatr Infect Dis J. 2007;26:806-10 pubmed
    ..Pertussis incidence remains high among adults implying that coverage rates regarding booster vaccinations for adolescents and adults still are too low. Reinforced application of the current booster strategy is needed. ..
  53. Advani A, Donnelly D, Gustafsson L, Hallander H. Changes of the Swedish Bordetella pertussis population in incidence peaks during an acellular pertussis vaccine period between 1997 and 2004. APMIS. 2007;115:299-310 pubmed
    ..Although vaccination with Pa has reduced disease, new variants have emerged representing clones surviving in the immunized population. ..
  54. Riffelmann M, Littmann M, Hülsse C, O Brien J, Wirsing von König C. [Pertussis: incidence, symptoms and costs]. Dtsch Med Wochenschr. 2006;131:2829-34 pubmed
    ..Pertussis is a frequent cause of longer lasting cough in German adults, and it causes significant morbidity and costs. ..
  55. Sawal M, Cohen M, Irazuzta J, Kumar R, Kirton C, Brundler M, et al. Fulminant pertussis: a multi-center study with new insights into the clinico-pathological mechanisms. Pediatr Pulmonol. 2009;44:970-80 pubmed publisher
    ..Cellular apoptosis appeared to underlay much of these changes. The secondary immuno-compromise may facilitate co-infection...
  56. Haberling D, Holman R, Paddock C, Murphy T. Infant and maternal risk factors for pertussis-related infant mortality in the United States, 1999 to 2004. Pediatr Infect Dis J. 2009;28:194-8 pubmed publisher
    ..Infants aged <12 months have the highest rates of complications and death from pertussis of any age group. Factors that increase the risk of pertussis-related death in infants are not well defined...
  57. Rank C, Quinn H, McIntyre P. Pertussis vaccine effectiveness after mass immunization of high school students in Australia. Pediatr Infect Dis J. 2009;28:152-3 pubmed publisher
    ..7-87.6%) for all study cases (n = 167), increasing to 85.4% (95% CI: 83.0-87.5%) for laboratory-confirmed cases (n = 155). Effectiveness should be comparable in settings with similar programs, such as the United States and Canada...
  58. Kowalzik F, Barbosa A, Fernandes V, Carvalho P, Avila Aguero M, Goh D, et al. Prospective multinational study of pertussis infection in hospitalized infants and their household contacts. Pediatr Infect Dis J. 2007;26:238-42 pubmed
    ..We studied the disease burden of pertussis in pediatric intensive care units and the source of infection in several Asian, European and Latin American countries...
  59. Wymann M, Richard J, Vidondo B, Heininger U. Prospective pertussis surveillance in Switzerland, 1991-2006. Vaccine. 2011;29:2058-65 pubmed publisher
    ..The benefits of further booster doses in adolescents and/or adults need to be considered...
  60. Vandebriel R, Gremmer E, Vermeulen J, Hellwig S, Dormans J, Roholl P, et al. Lung pathology and immediate hypersensitivity in a mouse model after vaccination with pertussis vaccines and challenge with Bordetella pertussis. Vaccine. 2007;25:2346-60 pubmed
    ..In summary, after challenge vaccination increased lung pathology, TNF-alpha expression (only WCV), and IH parameters. Th1 cells were critical for clearance...
  61. Frampton J, Keam S. Reduced-antigen, combined diphtheria-tetanus-acellular pertussis vaccine, adsorbed (Boostrix) US formulation): use as a single-dose booster immunization in adolescents aged 10-18 years. Paediatr Drugs. 2006;8:189-95; discussion 196 pubmed
  62. Hallander H, Andersson M, Gustafsson L, Ljungman M, Netterlid E. Seroprevalence of pertussis antitoxin (anti-PT) in Sweden before and 10 years after the introduction of a universal childhood pertussis vaccination program. APMIS. 2009;117:912-22 pubmed publisher
  63. Marzouqi I, Richmond P, Fry S, Wetherall J, Mukkur T. Development of improved vaccines against whooping cough: current status. Hum Vaccin. 2010;6:543-53 pubmed
    Prior to the introduction of killed whole cell pertussis vaccine [wP] in the 1940s, whooping cough was a major cause of infant death worldwide...
  64. Launay O, Toneatti C, Bernede C, Njamkepo E, Petitprez K, Leblond A, et al. Antibodies to tetanus, diphtheria and pertussis among healthy adults vaccinated according to the French vaccination recommendations. Hum Vaccin. 2009;5:341-6 pubmed
    ..They also indicate the need for better implementation of the current recommendations for pertussis-vaccine boosters in adults...