gram negative bacterial infections


Summary: Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.

Top Publications

  1. Bait Merabet L, Thille A, Legrand P, Brun Buisson C, Cattoir V. Brachyspira pilosicoli bloodstream infections: case report and review of the literature. Ann Clin Microbiol Antimicrob. 2008;7:19 pubmed publisher
    ..Finally, difficulties in rapid and accurate diagnosis of B. pilosicoli bloodstream infections, in vitro antimicrobial susceptibility of human clinical isolates, and therapeutic options are discussed...
  2. Schmiedel D, Epple H, Loddenkemper C, Ignatius R, Wagner J, Hammer B, et al. Rapid and accurate diagnosis of human intestinal spirochetosis by fluorescence in situ hybridization. J Clin Microbiol. 2009;47:1393-401 pubmed publisher
    ..In conclusion, FISH provides a fast and accurate technique for the visualization and identification of intestinal spirochetes in tissue sections. It therefore represents a valuable tool for routine diagnosis of HIS...
  3. Sahin I, Barut H. Quinolone-resistant Aeromonas hydrophila peritonitis in a CAPD patient. Clin Nephrol. 2010;73:241-3 pubmed
    ..The patient was treated successfully with intravenous ceftazidime for 2 days followed by intraperitoneal ceftazidime for 12 days. She was discharged with complete recovery after 2 weeks of antibiotic treatment. ..
  4. Yoon S, Choi N, Yun S. Detecting bacterial growth in continuous ambulatory peritoneal dialysis effluent using two culture methods. Korean J Intern Med. 2010;25:82-5 pubmed publisher
    ..001). The blood culture method using the BacT/Alert system is useful for culturing dialysates and improves the positive culture rate in patients with suspected peritonitis compared to the conventional culture method. ..
  5. Osorio C, Juiz Río S, Lemos M. The ABC-transporter hutCD genes of Photobacterium damselae subsp. piscicida are essential for haem utilization as iron source and are expressed during infection in fish. J Fish Dis. 2010;33:649-55 pubmed publisher
    ..The results demonstrate for the first time that haem uptake genes of a fish pathogen are expressed during the infective process in fish. ..
  6. Mu Y, Ding F, Cui P, Ao J, Hu S, Chen X. Transcriptome and expression profiling analysis revealed changes of multiple signaling pathways involved in immunity in the large yellow croaker during Aeromonas hydrophila infection. BMC Genomics. 2010;11:506 pubmed publisher
  7. Li R, Wang J, Wang X, Wang M. Pleural effusion adenosine deaminase: a candidate biomarker to discriminate between Gram-negative and Gram-positive bacterial infections of the pleural space. Clinics (Sao Paulo). 2016;71:271-5 pubmed publisher
    ..Pleural effusion adenosine deaminase is a helpful alternative biomarker for early and quick discrimination of Gram-negative from Gram-positive bacterial infections of the pleural space, which is useful for the selection of antibiotics. ..
  8. Testro A, Gow P, Angus P, Wongseelashote S, Skinner N, Markovska V, et al. Effects of antibiotics on expression and function of Toll-like receptors 2 and 4 on mononuclear cells in patients with advanced cirrhosis. J Hepatol. 2010;52:199-205 pubmed publisher
  9. Manchandani P, Zhou J, Babic J, Ledesma K, Truong L, Tam V. Role of Renal Drug Exposure in Polymyxin B-Induced Nephrotoxicity. Antimicrob Agents Chemother. 2017;61: pubmed publisher
    ..The onset of polymyxin B-induced nephrotoxicity is correlated with the renal drug exposure. In addition, megalin appears to play a pivotal role in the renal accumulation of polymyxin B, which might contribute to nephrotoxicity. ..

More Information

Publications116 found, 100 shown here

  1. Chen L, Paquette N, Mamoor S, Rus F, Nandy A, Leszyk J, et al. Innate immune signaling in Drosophila is regulated by transforming growth factor ? (TGF?)-activated kinase (Tak1)-triggered ubiquitin editing. J Biol Chem. 2017;292:8738-8749 pubmed publisher
    ..This ubiquitin-editing process results in the proteasomal degradation of Imd, which we propose functions to restore homeostasis to the Drosophila immune response. ..
  2. Latallo M, Cortina G, Faham S, Nakamoto R, Kasson P. Predicting allosteric mutants that increase activity of a major antibiotic resistance enzyme. Chem Sci. 2017;8:6484-6492 pubmed publisher
    ..These findings show how molecular simulation can predict how allosteric mutations alter active-site conformational equilibria to increase catalytic rates and thus resistance against common clinically used antibiotics...
  3. Botrel M, Haenni M, Morignat E, Sulpice P, Madec J, Calavas D. Distribution and antimicrobial resistance of clinical and subclinical mastitis pathogens in dairy cows in Rhône-Alpes, France. Foodborne Pathog Dis. 2010;7:479-87 pubmed publisher
    ..However, it also confirms the fact that attention must be maintained to avoid any emergence of such resistant bacteria. ..
  4. von Baum H, Bommer M, Forke A, Holz J, Frenz P, Wellinghausen N. Is domestic tap water a risk for infections in neutropenic patients?. Infection. 2010;38:181-6 pubmed publisher
  5. Asghar A, Faidah H. Frequency and antimicrobial susceptibility of gram-negative bacteria isolated from 2 hospitals in Makkah, Saudi Arabia. Saudi Med J. 2009;30:1017-23 pubmed
    ..The implementation of monitoring programs is an important part of the prevention strategy against the development of antibiotic resistance in hospitals. ..
  6. Piroth L, Pechinot A, Minello A, Jaulhac B, Patry I, Hadou T, et al. Bacterial epidemiology and antimicrobial resistance in ascitic fluid: a 2-year retrospective study. Scand J Infect Dis. 2009;41:847-51 pubmed publisher
    ..Repeated epidemiological surveys and new clinical trials are thus needed...
  7. Doung ngern P, Vatanaprasan T, Chungpaibulpatana J, Sitamanoch W, Netwong T, Sukhumkumpee S, et al. Infections and treatment of wounds in survivors of the 2004 Tsunami in Thailand. Int Wound J. 2009;6:347-54 pubmed publisher
    ..This report suggests that wounds should be aggressively debrided and suturing postponed if possible. Patients should be given broad spectrum antibiotics to assist with wound healing. ..
  8. Ibrahem M, Fathi M, Mesalhy S, Abd El Aty A. Effect of dietary supplementation of inulin and vitamin C on the growth, hematology, innate immunity, and resistance of Nile tilapia (Oreochromis niloticus). Fish Shellfish Immunol. 2010;29:241-6 pubmed publisher
    ..niloticus) in aquaculture. ..
  9. Keller P, Rampini S, Bloemberg G. Detection of a mixed infection in a culture-negative brain abscess by broad-spectrum bacterial 16S rRNA gene PCR. J Clin Microbiol. 2010;48:2250-2 pubmed publisher
  10. Liu Z, Wilson Welder J, Hostetter J, Jergens A, Wannemuehler M. Prophylactic treatment with Hypoxis hemerocallidea corm (African potato) methanolic extract ameliorates Brachyspira hyodysenteriae-induced murine typhlocolitis. Exp Biol Med (Maywood). 2010;235:222-30 pubmed publisher
    ..hyodysenteriae-induced typhlocolitis, suggesting H. hemerocallidea corm methanolic extract may have potential for ameliorating enteropathies that are mediated by overactive host inflammatory processes...
  11. Adjide C, De Meyer A, Weyer M, Obin O, Lamory F, Lesueur C, et al. [A sensitive, specific and predictive isolation medium developed for Stenotrophomonas maltophilia study in healthcare settings]. Pathol Biol (Paris). 2010;58:11-7 pubmed publisher
    ..SM2i is a selective, specific, predictive medium which can allow easily isolating and identifying accurately Smalto in environmental samples. Its evaluation on clinical samples is on going. ..
  12. Hejnar P, Kolar M, Sauer P. Antibiotic resistance of Stenotrophomonas maltophilia strains isolated from captive snakes. Folia Microbiol (Praha). 2010;55:83-7 pubmed publisher
  13. Chuang K, Elford E, Tseng J, Leung B, Harris H. An expanding role for apolipoprotein E in sepsis and inflammation. Am J Surg. 2010;200:391-7 pubmed publisher
    ..These results indicate an endogenous ligand, not LPS, may be responsible for NKT activation. A molecular remnant similar to iGb3 could act as a damage-associated molecular pattern and play a prominent role in animal models of sepsis. ..
  14. Hsieh P, Lee M, Hsu K, Chang Y, Shih H, Ueng S. Gram-negative prosthetic joint infections: risk factors and outcome of treatment. Clin Infect Dis. 2009;49:1036-43 pubmed publisher
    ..Resection of the prosthesis, with or without subsequent reimplantation, as a result of GN PJI is associated with a favorable outcome rate that is comparable to that associated with PJI due to GP pathogens. ..
  15. Taşbakan M, Yamazhan T, Aydemir S, Bacakoglu F. [A case of ventilator-associated pneumonia caused by Cupriavidus pauculus]. Mikrobiyol Bul. 2010;44:127-31 pubmed
    ..Clinical and microbiological resolution was achieved by imipenem therapy. In conclusion, rare pathogens like C. pauculus should be considered among the possible causative agents in infections that develop in immunocompromised host. ..
  16. Razvi S, Quittell L, Sewall A, Quinton H, Marshall B, Saiman L. Respiratory microbiology of patients with cystic fibrosis in the United States, 1995 to 2005. Chest. 2009;136:1554-1560 pubmed publisher
    ..Future studies should continue to monitor changing trends and define the association between these trends and care practices in CF. ..
  17. Lambden S, Akeru J, Barrett N. Acute intravascular haemolysis associated with intravenous administration of meropenem in a sixty four year old man. Can J Clin Pharmacol. 2010;17:e64-6 pubmed
    ..We discuss the possible mechanisms involved in the development of drug induced haemolysis and suggest the most likely cause in this case. ..
  18. Ingerslev H, Lunder T, Nielsen M. Inflammatory and regenerative responses in salmonids following mechanical tissue damage and natural infection. Fish Shellfish Immunol. 2010;29:440-50 pubmed publisher
    ..Further, in both studies the regenerative genes TGF-beta, MMP-2, CTGF, myostatin-1alphabeta were induced, but showed different kinetics. Collagen-1alpha was only induced in infected fish, probably due to heavier tissue damage in these...
  19. Foley S, Lynne A, Nayak R. Molecular typing methodologies for microbial source tracking and epidemiological investigations of Gram-negative bacterial foodborne pathogens. Infect Genet Evol. 2009;9:430-40 pubmed publisher
    ..Salmonella enterica, Shigella spp., Escherichia coli, and Yersinia enterocolitica. ..
  20. Teng S, Ou T, Hsieh Y, Lee W, Lin Y, Lee W. Complicated intra-abdominal infection caused by extended drug-resistant Achromobacter xylosoxidans. J Microbiol Immunol Infect. 2009;42:176-80 pubmed
    ..Culture of both blood and ascites yielded extended drug-resistant A. xylosoxidans, which was only sensitive to colistin. The clinical and laboratory characteristics of A. xylosoxidans are presented. ..
  21. Wamisho B, Bates J, Tompkins M, Islam R, Nyamulani N, Ngulube C, et al. Ward round--crocodile bites in Malawi: microbiology and surgical management. Malawi Med J. 2009;21:29-31 pubmed
    ..An antibiotic regime is recommended that covers gram negative rods, anaerobes and may include doxycycline, as well as the need to have a low threshold for early amputation...
  22. Janda J, Abbott S. The genus Aeromonas: taxonomy, pathogenicity, and infection. Clin Microbiol Rev. 2010;23:35-73 pubmed publisher
    ..This article provides an extensive review of these topics, in addition to others, such as taxonomic issues, microbial pathogenicity, and antimicrobial resistance markers...
  23. Balcázar J, Vendrell D, de Blas I, Ruiz Zarzuela I, Múzquiz J. Effect of Lactococcus lactis CLFP 100 and Leuconostoc mesenteroides CLFP 196 on Aeromonas salmonicida Infection in brown trout (Salmo trutta). J Mol Microbiol Biotechnol. 2009;17:153-7 pubmed publisher
  24. Lekunberri I, Balcázar J, Borrego C. Detection and quantification of the plasmid-mediated mcr-1 gene conferring colistin resistance in wastewater. Int J Antimicrob Agents. 2017;50:734-736 pubmed publisher
    ..05), suggesting that colistin resistance has increased over time. This study gives evidence of the growing spread of mcr-1 and provides a real-time PCR assay for its rapid detection and quantification. ..
  25. Tunsjø H, Paulsen S, Berg K, Sørum H, L abée Lund T. The winter ulcer bacterium Moritella viscosa demonstrates adhesion and cytotoxicity in a fish cell model. Microb Pathog. 2009;47:134-42 pubmed publisher
    ..These processes can also occur at temperatures above those experienced from winter ulcer outbreaks. However, the adhesion mechanisms appear to be temperature regulated and may contribute to temperature dependent disease outbreaks...
  26. Zhou L, Wang X, Liu Q, Wang Q, Zhao Y, Zhang Y. A novel multivalent vaccine based on secretary antigen-delivery induces protective immunity against Vibrio anguillarum and Aeromonas hydrophila. J Biotechnol. 2010;146:25-30 pubmed publisher
    ..anguillarum and A. hydrophila, suggesting that this vector vaccine had great potential in serving as a valuable multivalent live vaccine. ..
  27. Tubau F, Liñares J, Rodríguez M, Cercenado E, Aldea M, González Romo F, et al. Susceptibility to tigecycline of isolates from samples collected in hospitalized patients with secondary peritonitis undergoing surgery. Diagn Microbiol Infect Dis. 2010;66:308-13 pubmed publisher
    ..Tigecycline offers an adequate activity profile against isolates from secondary peritonitis when tested by Etest regardless of the breakpoints used for categorization. ..
  28. Zhong C, Cheng A, Wang M, Zhu D, Luo Q, Zhong C, et al. Antibiotic susceptibility of Riemerella anatipestifer field isolates. Avian Dis. 2009;53:601-7 pubmed
  29. Fulton R, Rimler R. Epidemiologic investigation of Riemerella anatipestifer in a commercial duck company by serotyping and DNA fingerprinting. Avian Dis. 2010;54:969-72 pubmed
    ..These findings add additional proof of the value of DNA fingerprinting in disease outbreak investigations and further support the importance of implementing biosecurity protocols to stop the spread of disease-causing organisms. ..
  30. Llosa M, Roy C, Dehio C. Bacterial type IV secretion systems in human disease. Mol Microbiol. 2009;73:141-51 pubmed publisher
    ..Our increasing knowledge of the biology of T4S systems improves our ability to exploit them as biotechnological tools or to use them as novel targets for a new generation of antimicrobials. ..
  31. Magni A, Trancassini M, Varesi P, Iebba V, Curci A, Pecoraro C, et al. Achromobacter xylosoxidans genomic characterization and correlation of randomly amplified polymorphic DNA profiles with relevant clinical features [corrected] of cystic fibrosis patients. J Clin Microbiol. 2010;48:1035-9 pubmed publisher
    ..xylosoxidans. These findings seem to imply that the lung habitats found in CF patients are capable of shaping and selecting the colonizing bacterial flora, as seems to be the case for the A. xylosoxidans strains studied. ..
  32. Chen R, Zhou Z, Cao Y, Bai Y, Yao B. High yield expression of an AHL-lactonase from Bacillus sp. B546 in Pichia pastoris and its application to reduce Aeromonas hydrophila mortality in aquaculture. Microb Cell Fact. 2010;9:39 pubmed publisher
    ..In this study, we tried a new way to attenuate the A. hydrophila infection by using a quorum quenching strategy with a recombinant AHL-lactonase expressed in Pichia pastoris...
  33. Young K, Czyrny A, Russell S, Huber P, Lumsden J. Plasma ladderlectin concentration following sterile inflammation and Aeromonas salmonicida subsp. salmonicida infection. J Fish Dis. 2009;32:569-76 pubmed publisher
    ..These studies demonstrate that RTLL is not detectably induced during the trout APR to sterile inflammation or A. salmonicida infection, but plasma concentration of this protein may be reduced during bacterial infection. ..
  34. Rabagliati B R, Fuentes L G, Orellana U E, Oporto C J, Domínguez M I, Benítez G R, et al. [Etiology of febrile neutropenia episodes among cancer patients from Hospital Clinico Universidad Catolica, Santiago-Chile]. Rev Chilena Infectol. 2009;26:106-13 pubmed publisher
    ..045), respectively. The etiological profile of FN in our center and the necessity to continue the surveillance was described. Future studies are needed regarding risk factors of invasive infection that have worst prognosis. ..
  35. Chen W, Lin Y, Liang S, Tu C, Chen H, Hang L, et al. Hospital-acquired thoracic empyema in adults: a 5-year study. South Med J. 2009;102:909-14 pubmed publisher
    ..Choice of antibiotic treatment for HATE should be based on the etiology of the pleural infection. In treating HAP-related empyema, antibiotics should cover aerobic Gram-negative, polymicrobial, and anaerobic pathogens. ..
  36. Zheng W, Hu Y, Xiao Z, Sun L. Cloning and analysis of a ferritin subunit from turbot (Scophthalmus maximus). Fish Shellfish Immunol. 2010;28:829-36 pubmed publisher
    ..Taken together, these results suggest that SmFer1 is likely to play a role in both iron storage and immune defense against microbial infections...
  37. Credito K, Kosowska Shick K, Appelbaum P. Mutant prevention concentrations of four carbapenems against gram-negative rods. Antimicrob Agents Chemother. 2010;54:2692-5 pubmed publisher
    ..aeruginosa the MPC/MIC ratios were 4 to > or =16. The MPC/MIC ratios for beta-lactamase-positive K. pneumoniae and E. coli isolates were much higher (range, 4 to >16 microg/ml) than those for ss-lactamase-negative strains. ..
  38. Ronco C, Piccinni P, Kellum J. Rationale of extracorporeal removal of endotoxin in sepsis: theory, timing and technique. Contrib Nephrol. 2010;167:25-34 pubmed publisher
    ..Recent clinical results seem to confirm these expectations showing a reduction of mortality in patients with early signs of abdominal sepsis due to recent surgery. This opens a new avenue for intervention in sepsis. ..
  39. Malkan A, Strollo W, Scholand S, Dudrick S. Implanted-port-catheter-related sepsis caused by Acidovorax avenae and methicillin-sensitive Staphylococcus aureus. J Clin Microbiol. 2009;47:3358-61 pubmed publisher
    ..Human infections caused by members of the Comamonadaceae are extremely rare. We report a case of implanted-port-catheter-related sepsis caused by Acidovorax avenae and methicillin (meticillin)-sensitive Staphylococcus aureus (MSSA). ..
  40. Nawaz M, Khan S, Khan A, Sung K, Tran Q, Kerdahi K, et al. Detection and characterization of virulence genes and integrons in Aeromonas veronii isolated from catfish. Food Microbiol. 2010;27:327-31 pubmed publisher
    ..Our results indicate that farm-raised catfish may be a source of pathogenic A. veronii and that the potential health risks posed by virulent strains of A. veronii should not be underestimated. ..
  41. Sawa N, Ubara Y, Katori H, Hoshino J, Suwabe T, Takemoto F, et al. The long-term survival rate of catecholamine-resistant septic shock in Japanese patients who received vasopressin therapy. Clin Nephrol. 2009;72:129-36 pubmed
    ..The 28-day survival rate was 45% (25 patients). In Japanese septic shock patients, vasopressin infusion improved hemodynamic status and reduced catecholamine requirement, and 28-day survival rate was 45%. ..
  42. Bello López J, Fernández Rendón E, Curiel Quesada E. In vivo transfer of plasmid pRAS1 between Aeromonas salmonicida and Aeromonas hydrophila in artificially infected Cyprinus carpio L. J Fish Dis. 2010;33:251-9 pubmed publisher
    ..Implications of this plasmid transfer in natural settings and its possible consequences to human health are discussed...
  43. Abe R, Oda S, Sadahiro T, Nakamura M, Hirayama Y, Tateishi Y, et al. Gram-negative bacteremia induces greater magnitude of inflammatory response than Gram-positive bacteremia. Crit Care. 2010;14:R27 pubmed publisher
  44. Sharma A, Kumar S, Wanchu A, Sharma K, Sharma N, Singh R, et al. Clinical characteristics and predictors of mortality in 67 patients with primary pyomyositis: a study from North India. Clin Rheumatol. 2010;29:45-51 pubmed publisher
    ..In our study, the patients were seen almost a decade later than those seen in other studies from the region. Evidence of organ dysfunction at presentation and sepsis was associated with increased mortality...
  45. Bert F, Larroque B, Paugam Burtz C, Janny S, Durand F, Dondero F, et al. Microbial epidemiology and outcome of bloodstream infections in liver transplant recipients: an analysis of 259 episodes. Liver Transpl. 2010;16:393-401 pubmed publisher
    ..47). In conclusion, BSIs are frequent and early complications after liver transplantation and are mostly caused by gram-negative bacilli. A BSI in the first posttransplant month is a significant predictor of 1-year survival. ..
  46. Ye Y, Xu X, Li J. Emergence of CTX-M-3, TEM-1 and a new plasmid-mediated MOX-4 AmpC in a multiresistant Aeromonas caviae isolate from a patient with pneumonia. J Med Microbiol. 2010;59:843-7 pubmed publisher
    ..This new plasmid-mediated AmpC beta-lactamase from China was named MOX-4. This is believed to be the first report of MOX-4, CTX-M-3 and TEM-1 beta-lactamases in a multiresistant A. caviae. ..
  47. Akhtar N, Alqurashi A, Abu Twibah M. In vitro ciprofloxacin resistance profiles among gram-negative bacteria isolated from clinical specimens in a teaching hospital. J Pak Med Assoc. 2010;60:625-7 pubmed
    ..e. E. coli, K. pneumoniae, E. cloacae, E. aerogenes, P. aeruginosa and Pseudomonas spp showing that ciprofloxacin is no more a drug of choice for gram negative infections by these microbes. ..
  48. Yong M, Buising K, Cheng A, Thursky K. Improved susceptibility of Gram-negative bacteria in an intensive care unit following implementation of a computerized antibiotic decision support system. J Antimicrob Chemother. 2010;65:1062-9 pubmed publisher
  49. Ribeiro N, Heath C, Kierath J, Rea S, Duncan Smith M, Wood F. Burn wounds infected by contaminated water: case reports, review of the literature and recommendations for treatment. Burns. 2010;36:9-22 pubmed publisher
    ..We describe commonly reported organisms from various water sources, the appropriate initial empirical antimicrobial chemotherapy and present the clinician with a proposed algorithm for managing these serious infections...
  50. Gupta A, Swaroop C, Agarwala S, Pandey R, Bakhshi S. Randomized controlled trial comparing oral amoxicillin-clavulanate and ofloxacin with intravenous ceftriaxone and amikacin as outpatient therapy in pediatric low-risk febrile neutropenia. J Pediatr Hematol Oncol. 2009;31:635-41 pubmed publisher
    ..Outpatient oral therapy is infrequently used in pediatric low-risk febrile neutropenia (LRFN) as there is insufficient data regarding its equivalence as compared with parenteral therapy...
  51. Dellinger R, Tomayko J, Angus D, Opal S, Cupo M, McDermott S, et al. Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trial. Crit Care Med. 2009;37:2929-38 pubmed publisher
    ..Endotoxin neutralization correlates with the amount of phospholipid in the lipoprotein particles...
  52. Wistbacka S, Lönnström L, Bonsdorff E, Bylund G. Thiaminase activity of crucian carp Carassius carassius injected with a bacterial fish pathogen, Aeromonas salmonicida subsp. salmonicida. J Aquat Anim Health. 2009;21:217-28 pubmed publisher
    ..It is suggested that the health of fish should be considered when searching for factor(s) affecting its thiaminase activity...
  53. Borcan E, Ghiţă C, Chifiriuc M, Măruţescu L, Isar C, Lazar V. Antibiotic resistance of Gram negative bacilli strains isolated from the Intensive Care Unit in Fundeni Clinical Institute, Bucharest, Romania. Roum Arch Microbiol Immunol. 2009;68:228-34 pubmed
  54. Chishti A, Maul E, Nazario R, Bennett J, Kiessling S. A guideline for the inpatient care of children with pyelonephritis. Ann Saudi Med. 2010;30:341-9 pubmed publisher
    ..No established guideline exists for older children and the AAP guideline does not specifically focus on inpatient care...
  55. Robertson A, Griffin S, Murphy D, Pearson J, Forrest I, Dark J, et al. Targeting allograft injury and inflammation in the management of post-lung transplant bronchiolitis obliterans syndrome. Am J Transplant. 2009;9:1272-8 pubmed publisher
    ..The need for further evidence, including randomized-controlled trials, to evaluate the role of medical and surgical therapies is emphasized by the current literature...
  56. Zipfel P. Complement and immune defense: from innate immunity to human diseases. Immunol Lett. 2009;126:1-7 pubmed publisher
    ..This can result in diseases, like severe renal diseases hemolytic uremic syndrome (HUS) and dense deposit disease (DDD), in age related macular degeneration a common form of blindness and also in other forms of autoimmune diseases...
  57. Singh A, Mishra B, Thakur A. Multidrug-resistant Gram-negative bacteria in postoperative infections. J Indian Med Assoc. 2009;107:148-50, 163 pubmed
    ..Amongst the 14 antibiotics tested, the percentage sensitivity against the multidrug-resistant Gram-negative isolates was highest for amikacin, meropenem, piperacillin + tazobactam and cefoperazone + sulbactam...
  58. Nya E, Austin B. Use of garlic, Allium sativum, to control Aeromonas hydrophila infection in rainbow trout, Oncorhynchus mykiss (Walbaum). J Fish Dis. 2009;32:963-70 pubmed publisher
  59. Novelli G, Ferretti G, Ruberto F, Morabito V, Pugliese F. Early management of endotoxemia using the endotoxin activity assay and polymyxin B-based hemoperfusion. Contrib Nephrol. 2010;167:91-101 pubmed publisher
    ..We evaluated the ability of the endotoxin activity (EA) assay to determine the need for early intervention for endotoxemia using polymyxin B-based hemoperfusion (PMX-DHP) on septic patients...
  60. Al Haddad C, Graure M, Grigore L, Niţescu R, Năşcuţiu A, Ionescu G. [Etiologic factors in urinary tract infection investigated in ambulatory setting. Community-acquired urinary tract infection: etiologic aspects and antibiotic resistance]. Bacteriol Virusol Parazitol Epidemiol. 2009;54:17-22 pubmed
    ..Colimycine, phosphomycine, fluorurated quinolones were the most active on the Gram-negative flora, and the Gram-positive cocci were most frequently sensitive to amikacine, amoxycyline and ceftazidim...
  61. Hawser S, Bouchillon S, Hoban D, Badal R. Epidemiologic trends, occurrence of extended-spectrum beta-lactamase production, and performance of ertapenem and comparators in patients with intra-abdominal infections: analysis of global trend data from 2002-2007 from the SMART study. Surg Infect (Larchmt). 2010;11:371-8 pubmed publisher
    ..Results from SMART in 2002 through 2005 have been reported; this report summarizes aggregated data from SMART 2002-2007 to identify epidemiologic trends over time...
  62. Yaroustovsky M, Abramyan M, Popok Z, Nazarova E, Stupchenko O, Popov D, et al. Preliminary report regarding the use of selective sorbents in complex cardiac surgery patients with extensive sepsis and prolonged intensive care stay. Blood Purif. 2009;28:227-33 pubmed publisher
    ..The purpose of this publication is to evaluate the first experiences with the supplemental use of selective endotoxin adsorption cartridges in the treatment of critically ill patients complicated by severe sepsis after cardiac surgery...
  63. Zilberberg M, Shorr A, Micek S, Hoban A, Pham V, Doherty J, et al. Epidemiology and outcomes of hospitalizations with complicated skin and skin-structure infections: implications of healthcare-associated infection risk factors. Infect Control Hosp Epidemiol. 2009;30:1203-10 pubmed publisher
    ..Because prompt appropriate treatment is associated with better outcomes, we studied the epidemiology of healthcare-associated complicated skin and skin-structure infections (cSSSIs)...
  64. Chen C, Tsay W, Tang J, Tien H, Chen Y, Chang S, et al. Epidemiology of bloodstream infections in patients with haematological malignancies with and without neutropenia. Epidemiol Infect. 2010;138:1044-51 pubmed publisher
    ..calcoaceticus-baumannii complex and vancomycin-resistant enterococci were also found during the study period. Emerging antimicrobial resistant pathogens are an increasing threat to neutropenic cancer patients...
  65. Weintrob A, Roediger M, Barber M, Summers A, Fieberg A, Dunn J, et al. Natural history of colonization with gram-negative multidrug-resistant organisms among hospitalized patients. Infect Control Hosp Epidemiol. 2010;31:330-7 pubmed publisher
    ..To determine the anatomic sites and natural history of colonization with gram-negative multidrug-resistant organisms (MDROs)...
  66. Dettenkofer M, Utzolino S, Luft D, Lemmen S. [Effectiveness and risks of isolation precautions in patients with MRSA and other multidrug-resistant bacteria]. Zentralbl Chir. 2010;135:124-8 pubmed publisher
    ..Additional precautions, including single-room isolation, should be implemented critically if indicated...
  67. Zheng W, Hu Y, Zhang M, Sun L. Analysis of the expression and antioxidative property of a peroxiredoxin 6 from Scophthalmus maximus. Fish Shellfish Immunol. 2010;29:305-11 pubmed publisher
    ..Taken together, these results indicate that SmPrx6 is a Prx6 homologue with antioxidative property and is likely to be involved in both cellular maintenance and protective response during host immune defense against bacterial infection...
  68. Burgess D. Curbing resistance development: maximizing the utility of available agents. J Manag Care Pharm. 2009;15:S5-9 pubmed
    ..Effective treatment of VAP can be challenging due to a high prevalence of Pseudomonas aeruginosa and multidrug-resistant (MDR) pathogens as causative organisms...
  69. Lund V, Mikkelsen H, Schrøder M. Atypical furunculosis vaccines for Atlantic cod Gadhus morhua: impact of reattached Aeromonas salmonicida A-layer protein on vaccine efficacy. Dis Aquat Organ. 2009;85:115-22 pubmed publisher
    ..These results indicate that the A-layer protein when attached to the cell surface plays a role in inducing protective immunity in cod...
  70. Sauer M, Altrichter J, Kreutzer H, Schmidt H, Nöldge Schomburg G, Schmidt R, et al. Safety evaluation for a cell-based immune support system in an ex vivo rat model of gram-negative sepsis. Ther Apher Dial. 2009;13:444-50 pubmed publisher
    ..001). The data suggest that extracorporeal use of granulocytes allows the therapeutic use of these cells while avoiding unwanted effects resulting from direct contact to internal organs...
  71. Myers S, Dunn P, Phillips N, La T, Hampson D. Brachyspira intermedia and Brachyspira pilosicoli are commonly found in older laying flocks in Pennsylvania. Avian Dis. 2009;53:533-7 pubmed
    ..Colonization with pathogenic Brachyspira species, and particularly B. intermedia, occurs very commonly in layer flocks >40 wk of age in Pennsylvania. The significance of this high rate of colonization requires further investigation...
  72. Ousey J, Palmer L, Cash R, Grimes K, Fletcher A, Barrelet A, et al. An investigation into the suitability of a commercial real-time PCR assay to screen for Taylorella equigenitalis in routine prebreeding equine genital swabs. Equine Vet J. 2009;41:878-82 pubmed
    ..Standard bacteriological methods for identifying Taylorella equigenitalis in cervical smears are time consuming. Therefore, a more rapid real-time PCR assay was evaluated for its suitability in screening swabs...
  73. Hoetzenecker K, Ankersmit H, Lang G, Scheed A, Marta G, Jaksch P, et al. Considerations on infectious complications using a drowned lung for transplantation. Transpl Int. 2010;23:e32-4 pubmed publisher
    ..Based on this case we propose standard procedures, which should be followed when considering drowned donor lungs, in order to minimize risks for infectious complications...
  74. Endimiani A, Hujer A, Hujer K, Gatta J, Schriver A, Jacobs M, et al. Evaluation of a commercial microarray system for detection of SHV-, TEM-, CTX-M-, and KPC-type beta-lactamase genes in Gram-negative isolates. J Clin Microbiol. 2010;48:2618-22 pubmed publisher
    ..A total of 106 Gram-negative strains were tested. The following sensitivity and specificity results were recorded, respectively: for bla(SHV), 98.8% and 100%; for bla(TEM), 100% and 96.4%; and for bla(CTX-M) and bla(KPC), 100% and 100%...
  75. Vesentini S, Soncini M, Fiore G, Redaelli A. Mechanisms of polymyxin B endotoxin removal from extracorporeal blood flow: molecular interactions. Contrib Nephrol. 2010;167:45-54 pubmed publisher
  76. Chang W, Lu C. Diagnosis and management of adult bacterial meningitis. Acta Neurol Taiwan. 2009;18:3-13 pubmed
    ..This review may help first-line, primary-care neurologists have a better view on handling this critical central nervous system infection...
  77. Lautenbach E, Marsicano R, Tolomeo P, Heard M, Serrano S, Stieritz D. Epidemiology of antimicrobial resistance among gram-negative organisms recovered from patients in a multistate network of long-term care facilities. Infect Control Hosp Epidemiol. 2009;30:790-3 pubmed publisher
    ..The prevalence of resistance varied significantly by facility type, size, and geographic location...
  78. Schirmer P, Deresinski S. Ceftobiprole: a new cephalosporin for the treatment of skin and skin structure infections. Expert Rev Anti Infect Ther. 2009;7:777-91 pubmed publisher
    ..aureus and Gram-negative pathogens including cefepime-sensitive P. aeruginosa may be involved...
  79. Ota K, Kazawa T, Tsubata C, Suzuki M, Imaoka K. [An autopsy case involving severe sepsis due to Capnocytophaga canimorsus infection]. Kansenshogaku Zasshi. 2009;83:661-4 pubmed
    ..canimorsus infection after a dog bite who died less than 12 hours after admission. We observed neutrophils with intracytoplasmic bacilli in the peripheral blood smear. We discuss clinical presentation and autopsy findings...
  80. Douidah L, De Zutter L, Vandamme P, Houf K. Identification of five human and mammal associated Arcobacter species by a novel multiplex-PCR assay. J Microbiol Methods. 2010;80:281-6 pubmed publisher
    ..Furthermore, examination of the 23 S RNA gene of A. cryaerophilus revealed, besides large heterogeneity, the presence of intervening sequences ranging from 87 to 196 bp...
  81. Tsinganou E, Gebbers J. Human intestinal spirochetosis--a review. Ger Med Sci. 2010;8:Doc01 pubmed publisher
    ..Rare cases of spirochetemia and multiple organ failure have been reported in critically ill patients with IS...
  82. Juretschko S, Beavers May T, Stovall S. Nosocomial infection with Asaia lannensis in two paediatric patients with idiopathic dilated cardiomyopathy. J Med Microbiol. 2010;59:848-52 pubmed publisher
    ..These isolates of A. lannensis showed an unfavourable susceptibility pattern including resistance to carbapenems, all beta-lactam agents and fluoroquinolones...
  83. Meade B, Timoney P, Donahue J, Branscum A, Ford R, Rowe R. Initial occurrence of Taylorella asinigenitalis and its detection in nurse mares, a stallion and donkeys in Kentucky. Prev Vet Med. 2010;95:292-6 pubmed publisher
    ..Seventy-one percent of infected mares required more than one course of treatment to clear the organism from their reproductive tracts and one mare harbored the organism for more than 300 days...
  84. Otter J, Yezli S, Schouten M, van Zanten A, Houmes Zielman G, Nohlmans Paulssen M. Hydrogen peroxide vapor decontamination of an intensive care unit to remove environmental reservoirs of multidrug-resistant gram-negative rods during an outbreak. Am J Infect Control. 2010;38:754-6 pubmed publisher
    ..No new cases of Acinetobacter were identified for approximately 3 months after HPV...
  85. Shitaye D, Asrat D, Woldeamanuel Y, Worku B. Risk factors and etiology of neonatal sepsis in Tikur Anbessa University Hospital, Ethiopia. Ethiop Med J. 2010;48:11-21 pubmed
    ..Neonatal sepsis is one of the most common reasons for admission to neonatal units in developing countries. It is also a major cause of mortality in both developed and developing countries...
  86. Vlieghe E, Phoba M, Tamfun J, Jacobs J. Antibiotic resistance among bacterial pathogens in Central Africa: a review of the published literature between 1955 and 2008. Int J Antimicrob Agents. 2009;34:295-303 pubmed publisher
    ..These data could enable redaction of local treatment guidelines and fuel national and regional policies to contain antimicrobial resistance...
  87. Hyvärinen K, Laitinen S, Paju S, Hakala A, Suominen Taipale L, Skurnik M, et al. Detection and quantification of five major periodontal pathogens by single copy gene-based real-time PCR. Innate Immun. 2009;15:195-204 pubmed publisher
    ..821 (95% CI, 0.758-0.885, P50.001). Our prominently sensitive and specific assay may have major importance in the diagnosis, prevention, and treatment of periodontitis...
  88. Chi H, Chang K, Chang H, Chiu N, Huang F. Infections associated with indwelling ventriculostomy catheters in a teaching hospital. Int J Infect Dis. 2010;14:e216-9 pubmed publisher
    ..Ventriculostomy-associated infections are a serious complication of external ventricular drains. The objective of this study was to analyze the clinical features of and risk factors for such infections...
  89. Sanchez M, Hernandez A, Martinez J. Stenotrophomonas maltophilia drug resistance. Future Microbiol. 2009;4:655-60 pubmed publisher
    ..Future studies are required to fully understand the mechanisms of resistance, their regulation and potential crosstalk with S. maltophilia virulence, as well as the population dynamics of the different isolates of this bacterial species...
  90. De Cal M, Cazzavillan S, Cruz D, Nalesso F, Brendolan A, Rassu M, et al. [Methylobacterium radiotolerans bacteremia in hemodialysis patients]. G Ital Nefrol. 2009;26:616-20 pubmed
    ..7%) or CVC (29.7%) or both (67.6%). After removal and replacement of CVCs and antibiotic therapy and the strict application of an infection management protocol, there were no more fever episodes or cultures positive for M. radiotolerans...
  91. Ogata S, Higashiyama M, Adachi Y, Ohara I, Nishiyama J, Okusa Y, et al. Imprint cytology detects floating Brachyspira in human intestinal spirochetosis. Hum Pathol. 2010;41:249-54 pubmed publisher
    ..Further, we suggest the existence of differences in biological behavior between these spirochetes...
  92. Fontes M, Saavedra M, Monera A, Martins C, Martínez Murcia A. Phylogenetic identification of Aeromonas simiae from a pig, first isolate since species description. Vet Microbiol. 2010;142:313-6 pubmed publisher
    ..To our knowledge, this is the first time since species description that A. simiae is newly isolated and identified...