myxococcus xanthus

Summary

Summary: A species of gliding bacteria found on soil as well as in surface fresh water and coastal seawater.

Top Publications

  1. Yang Z, Hu W, Chen K, Wang J, Lux R, Zhou Z, et al. Alanine 32 in PilA is important for PilA stability and type IV pili function in Myxococcus xanthus. Microbiology. 2011;157:1920-8 pubmed publisher
    ..In the model organism Myxococcus xanthus, TFP act as molecular engines that power social (S) motility through cycles of extension and retraction...
  2. Zhang Y, Guzzo M, Ducret A, Li Y, Mignot T. A dynamic response regulator protein modulates G-protein-dependent polarity in the bacterium Myxococcus xanthus. PLoS Genet. 2012;8:e1002872 pubmed publisher
    ..Bacterial cells also regulate their polarity dynamically to reverse their direction of movement. In Myxococcus xanthus, a GTP-bound Ras-like G-protein, MglA, activates the motility machineries at the leading cell pole...
  3. Jakovljevic V, Leonardy S, Hoppert M, Søgaard Andersen L. PilB and PilT are ATPases acting antagonistically in type IV pilus function in Myxococcus xanthus. J Bacteriol. 2008;190:2411-21 pubmed publisher
    ..Here, we show that PilB and PilT of the T4P system in Myxococcus xanthus have ATPase activity in vitro...
  4. Bulyha I, Hot E, Huntley S, Søgaard Andersen L. GTPases in bacterial cell polarity and signalling. Curr Opin Microbiol. 2011;14:726-33 pubmed publisher
    ..The small Ras-like GTPase MglA together with its cognate GAP MglB regulates cell polarity in Myxococcus xanthus, and the small Ras-like GTPase CvnD9 in Streptomyces coelicolor is involved in signal transduction...
  5. Leonardy S, Miertzschke M, Bulyha I, Sperling E, Wittinghofer A, Søgaard Andersen L. Regulation of dynamic polarity switching in bacteria by a Ras-like G-protein and its cognate GAP. EMBO J. 2010;29:2276-89 pubmed publisher
    The rod-shaped cells of the bacterium Myxococcus xanthus move uni-directionally and occasionally undergo reversals during which the leading/lagging polarity axis is inverted...
  6. Ossa F, Diodati M, Caberoy N, Giglio K, Edmonds M, Singer M, et al. The Myxococcus xanthus Nla4 protein is important for expression of stringent response-associated genes, ppGpp accumulation, and fruiting body development. J Bacteriol. 2007;189:8474-83 pubmed
    Changes in gene expression are important for the landmark morphological events that occur during Myxococcus xanthus fruiting body development...
  7. Hu W, Wang J, Mchardy I, Lux R, Yang Z, Li Y, et al. Effects of exopolysaccharide production on liquid vegetative growth, stress survival, and stationary phase recovery in Myxococcus xanthus. J Microbiol. 2012;50:241-8 pubmed publisher
    Exopolysaccharide (EPS) of Myxococcus xanthus is a well-regulated cell surface component...
  8. Vos M, Velicer G. Social conflict in centimeter-and global-scale populations of the bacterium Myxococcus xanthus. Curr Biol. 2009;19:1763-7 pubmed publisher
    ..The predatory soil bacterium Myxococcus xanthus responds to starvation by cooperatively forming multicellular fruiting bodies in which a portion of the ..
  9. Treuner Lange A, Aguiluz K, van der Does C, Gómez Santos N, Harms A, Schumacher D, et al. PomZ, a ParA-like protein, regulates Z-ring formation and cell division in Myxococcus xanthus. Mol Microbiol. 2013;87:235-53 pubmed publisher
    ..Here, we show that lack of the ParA-like protein PomZ in Myxococcus xanthus resulted in division defects with the formation of chromosome-free minicells and filamentous cells...
  10. Zhang H, Rao N, Shiba T, Kornberg A. Inorganic polyphosphate in the social life of Myxococcus xanthus: motility, development, and predation. Proc Natl Acad Sci U S A. 2005;102:13416-20 pubmed
    ..b>Myxococcus xanthus, a social bacterium that feeds on other bacteria and forms fruiting bodies and spores, depends on poly P for ..

Detail Information

Publications109 found, 100 shown here

  1. Yang Z, Hu W, Chen K, Wang J, Lux R, Zhou Z, et al. Alanine 32 in PilA is important for PilA stability and type IV pili function in Myxococcus xanthus. Microbiology. 2011;157:1920-8 pubmed publisher
    ..In the model organism Myxococcus xanthus, TFP act as molecular engines that power social (S) motility through cycles of extension and retraction...
  2. Zhang Y, Guzzo M, Ducret A, Li Y, Mignot T. A dynamic response regulator protein modulates G-protein-dependent polarity in the bacterium Myxococcus xanthus. PLoS Genet. 2012;8:e1002872 pubmed publisher
    ..Bacterial cells also regulate their polarity dynamically to reverse their direction of movement. In Myxococcus xanthus, a GTP-bound Ras-like G-protein, MglA, activates the motility machineries at the leading cell pole...
  3. Jakovljevic V, Leonardy S, Hoppert M, Søgaard Andersen L. PilB and PilT are ATPases acting antagonistically in type IV pilus function in Myxococcus xanthus. J Bacteriol. 2008;190:2411-21 pubmed publisher
    ..Here, we show that PilB and PilT of the T4P system in Myxococcus xanthus have ATPase activity in vitro...
  4. Bulyha I, Hot E, Huntley S, Søgaard Andersen L. GTPases in bacterial cell polarity and signalling. Curr Opin Microbiol. 2011;14:726-33 pubmed publisher
    ..The small Ras-like GTPase MglA together with its cognate GAP MglB regulates cell polarity in Myxococcus xanthus, and the small Ras-like GTPase CvnD9 in Streptomyces coelicolor is involved in signal transduction...
  5. Leonardy S, Miertzschke M, Bulyha I, Sperling E, Wittinghofer A, Søgaard Andersen L. Regulation of dynamic polarity switching in bacteria by a Ras-like G-protein and its cognate GAP. EMBO J. 2010;29:2276-89 pubmed publisher
    The rod-shaped cells of the bacterium Myxococcus xanthus move uni-directionally and occasionally undergo reversals during which the leading/lagging polarity axis is inverted...
  6. Ossa F, Diodati M, Caberoy N, Giglio K, Edmonds M, Singer M, et al. The Myxococcus xanthus Nla4 protein is important for expression of stringent response-associated genes, ppGpp accumulation, and fruiting body development. J Bacteriol. 2007;189:8474-83 pubmed
    Changes in gene expression are important for the landmark morphological events that occur during Myxococcus xanthus fruiting body development...
  7. Hu W, Wang J, Mchardy I, Lux R, Yang Z, Li Y, et al. Effects of exopolysaccharide production on liquid vegetative growth, stress survival, and stationary phase recovery in Myxococcus xanthus. J Microbiol. 2012;50:241-8 pubmed publisher
    Exopolysaccharide (EPS) of Myxococcus xanthus is a well-regulated cell surface component...
  8. Vos M, Velicer G. Social conflict in centimeter-and global-scale populations of the bacterium Myxococcus xanthus. Curr Biol. 2009;19:1763-7 pubmed publisher
    ..The predatory soil bacterium Myxococcus xanthus responds to starvation by cooperatively forming multicellular fruiting bodies in which a portion of the ..
  9. Treuner Lange A, Aguiluz K, van der Does C, Gómez Santos N, Harms A, Schumacher D, et al. PomZ, a ParA-like protein, regulates Z-ring formation and cell division in Myxococcus xanthus. Mol Microbiol. 2013;87:235-53 pubmed publisher
    ..Here, we show that lack of the ParA-like protein PomZ in Myxococcus xanthus resulted in division defects with the formation of chromosome-free minicells and filamentous cells...
  10. Zhang H, Rao N, Shiba T, Kornberg A. Inorganic polyphosphate in the social life of Myxococcus xanthus: motility, development, and predation. Proc Natl Acad Sci U S A. 2005;102:13416-20 pubmed
    ..b>Myxococcus xanthus, a social bacterium that feeds on other bacteria and forms fruiting bodies and spores, depends on poly P for ..
  11. Perlova O, Fu J, Kuhlmann S, Krug D, Stewart A, Zhang Y, et al. Reconstitution of the myxothiazol biosynthetic gene cluster by Red/ET recombination and heterologous expression in Myxococcus xanthus. Appl Environ Microbiol. 2006;72:7485-94 pubmed
    ..Stigmatella aurantiaca DW4-3/1 into the chromosome of the thus far best-characterized myxobacterium, Myxococcus xanthus, in one step. The successful integration and expression of the myxothiazol biosynthetic genes in M...
  12. Otani M, Tabata J, Ueki T, Sano K, Inouye S. Heat-shock-induced proteins from Myxococcus xanthus. J Bacteriol. 2001;183:6282-7 pubmed
    Optimal conditions for two-dimensional gel electrophoresis of total cellular proteins from Myxococcus xanthus were established. Using these conditions, we analyzed protein patterns of heat-shocked M. xanthus cells...
  13. Müller F, Treuner Lange A, Heider J, Huntley S, Higgs P. Global transcriptome analysis of spore formation in Myxococcus xanthus reveals a locus necessary for cell differentiation. BMC Genomics. 2010;11:264 pubmed publisher
    b>Myxococcus xanthus is a Gram negative bacterium that can differentiate into metabolically quiescent, environmentally resistant spores...
  14. Nan B, Zusman D. Uncovering the mystery of gliding motility in the myxobacteria. Annu Rev Genet. 2011;45:21-39 pubmed publisher
    ..Recent studies on the motility of Myxococcus xanthus, a soil myxobacterium, suggest a likely mechanism for gliding in this organism. About forty M...
  15. Diodati M, Ossa F, Caberoy N, Jose I, Hiraiwa W, Igo M, et al. Nla18, a key regulatory protein required for normal growth and development of Myxococcus xanthus. J Bacteriol. 2006;188:1733-43 pubmed
    ..that a mutation in the ntrC-like activator gene nla18 causes defects in fruiting body development in Myxococcus xanthus. In this report, we describe the effect that nla18 inactivation has on gene expression patterns during ..
  16. Jroundi F, Fernandez Vivas A, Rodriguez Navarro C, Bedmar E, Gonzalez Muñoz M. Bioconservation of deteriorated monumental calcarenite stone and identification of bacteria with carbonatogenic activity. Microb Ecol. 2010;60:39-54 pubmed publisher
    ..The treatment consisted in the application of a nutritional solution (with and without Myxococcus xanthus inoculation) on decayed calcarenite stone blocks...
  17. Arshinoff B, Suen G, Just E, Merchant S, Kibbe W, Chisholm R, et al. Xanthusbase: adapting wikipedia principles to a model organism database. Nucleic Acids Res. 2007;35:D422-6 pubmed
    ..xanthusbase.org) is the official model organism database (MOD) for the social bacterium Myxococcus xanthus. In many respects, M...
  18. White D, Merod R, Thomasson B, Hartzell P. GidA is an FAD-binding protein involved in development of Myxococcus xanthus. Mol Microbiol. 2001;42:503-17 pubmed
    ..immediately upstream of aglU, a gene encoding a WD-repeat protein required for motility and development in Myxococcus xanthus. The GidA protein of M...
  19. Kraemer S, Toups M, Velicer G. Natural variation in developmental life-history traits of the bacterium Myxococcus xanthus. FEMS Microbiol Ecol. 2010;73:226-33 pubmed publisher
    The soil bacterium Myxococcus xanthus is a model for the study of cooperative microbial behaviours such as social motility and fruiting body formation. Several M...
  20. Schramm A, Lee B, Higgs P. Intra- and interprotein phosphorylation between two-hybrid histidine kinases controls Myxococcus xanthus developmental progression. J Biol Chem. 2012;287:25060-72 pubmed publisher
    ..The deltaproteobacterium Myxococcus xanthus contains a large repertoire of signaling proteins, many of which regulate its multicellular developmental ..
  21. Kimura Y, Ishida S, Matoba H, Okahisa N. RppA, a transducer homologue, and MmrA, a multidrug transporter homologue, are involved in the biogenesis and/or assembly of polysaccharide in Myxococcus xanthus. Microbiology. 2004;150:631-9 pubmed
    b>Myxococcus xanthus cells move by gliding, and form multicellular fruiting bodies under conditions of starvation...
  22. Nariya H, Inouye S. Modulating factors for the Pkn4 kinase cascade in regulating 6-phosphofructokinase in Myxococcus xanthus. Mol Microbiol. 2005;56:1314-28 pubmed
    b>Myxococcus xanthus, a Gram-negative developmental bacterium, contains a large number of protein Ser/Thr kinases (PSTKs). Among these PSTKs, Pkn4 has been shown to be 6-phosphofructokinase (PFK) kinase...
  23. Bulyha I, Schmidt C, Lenz P, Jakovljevic V, Höne A, Maier B, et al. Regulation of the type IV pili molecular machine by dynamic localization of two motor proteins. Mol Microbiol. 2009;74:691-706 pubmed publisher
    ..In Myxococcus xanthus, T4P are unipolarly localized and undergo pole-to-pole oscillations synchronously with cellular reversals...
  24. Wei X, Pathak D, Wall D. Heterologous protein transfer within structured myxobacteria biofilms. Mol Microbiol. 2011;81:315-26 pubmed publisher
    ..we investigated cis protein sequence and cellular behaviour requirements for lipoprotein transfer between Myxococcus xanthus cells...
  25. Konovalova A, Wegener Feldbrügge S, Søgaard Andersen L. Two intercellular signals required for fruiting body formation in Myxococcus xanthus act sequentially but non-hierarchically. Mol Microbiol. 2012;86:65-81 pubmed publisher
    Starvation-induced fruiting body formation in Myxococcus xanthus depends on intercellular signalling. A-signal functions after 2 h of starvation and its synthesis depends on the asg genes...
  26. Lopez Rubio J, Padmanabhan S, Lázaro J, Salas M, Murillo F, Elías Arnanz M. Operator design and mechanism for CarA repressor-mediated down-regulation of the photoinducible carB operon in Myxococcus xanthus. J Biol Chem. 2004;279:28945-53 pubmed
    The carB operon encodes all except one of the enzymes involved in light-induced carotenogenesis in Myxococcus xanthus. Expression of its promoter (P(B)) is repressed in the dark by sequence-specific DNA binding of CarA to a palindrome (pI)..
  27. Vos M, Velicer G. Genetic population structure of the soil bacterium Myxococcus xanthus at the centimeter scale. Appl Environ Microbiol. 2006;72:3615-25 pubmed
    b>Myxococcus xanthus is a gram-negative soil bacterium best known for its remarkable life history of social swarming, social predation, and multicellular fruiting body formation...
  28. Stein E, Cho K, Higgs P, Zusman D. Two Ser/Thr protein kinases essential for efficient aggregation and spore morphogenesis in Myxococcus xanthus. Mol Microbiol. 2006;60:1414-31 pubmed
    b>Myxococcus xanthus has a complex life cycle that involves vegetative growth and development. Previously, we described the espAB locus that is involved in timing events during the initial stages of fruiting body formation...
  29. Whitworth D, Millard A, Hodgson D, Hawkins P. Protein-protein interactions between two-component system transmitter and receiver domains of Myxococcus xanthus. Proteomics. 2008;8:1839-42 pubmed publisher
    ..The complex prokaryote Myxococcus xanthus possesses an unusually large number of TCS genes, many of which have no obvious interaction partners...
  30. Holmes A, Kalvala S, Whitworth D. Spatial simulations of myxobacterial development. PLoS Comput Biol. 2010;6:e1000686 pubmed publisher
    ..We show that a small number of physical properties in the model is sufficient to explain the most frequently documented population-level behaviours observed during development in Myxococcus xanthus.
  31. Müller F, Schink C, Hoiczyk E, Cserti E, Higgs P. Spore formation in Myxococcus xanthus is tied to cytoskeleton functions and polysaccharide spore coat deposition. Mol Microbiol. 2012;83:486-505 pubmed publisher
    b>Myxococcus xanthus is a Gram-negative bacterium that differentiates into environmentally resistant spores...
  32. Inouye S, Jain R, Ueki T, Nariya H, Xu C, Hsu M, et al. A large family of eukaryotic-like protein Ser/Thr kinases of Myxococcus xanthus, a developmental bacterium. Microb Comp Genomics. 2000;5:103-20 pubmed
    b>Myxococcus xanthus is a gram-negative bacterium that forms multicellular fruiting bodies upon starvation...
  33. Kruse T, Lobedanz S, Berthelsen N, Søgaard Andersen L. C-signal: a cell surface-associated morphogen that induces and co-ordinates multicellular fruiting body morphogenesis and sporulation in Myxococcus xanthus. Mol Microbiol. 2001;40:156-68 pubmed
    In Myxococcus xanthus, morphogenesis of multicellular fruiting bodies and sporulation are co-ordinated temporally and spatially...
  34. Caberoy N, Welch R, Jakobsen J, Slater S, Garza A. Global mutational analysis of NtrC-like activators in Myxococcus xanthus: identifying activator mutants defective for motility and fruiting body development. J Bacteriol. 2003;185:6083-94 pubmed
    The multicellular developmental cycle of Myxococcus xanthus requires large-scale changes in gene transcription, and recent findings indicate that NtrC-like activators play a prominent role in regulating these changes...
  35. Dickschat J, Wenzel S, Bode H, Muller R, Schulz S. Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus. Chembiochem. 2004;5:778-87 pubmed
    The volatiles emitted from cell cultures of myxobacterium Myxococcus xanthus were collected by use of a closed-loop stripping apparatus (CLSA) and analyzed by GC-MS...
  36. Kimura Y, Nakatuma H, Sato N, Ohtani M. Contribution of the cyclic nucleotide phosphodiesterases PdeA and PdeB to adaptation of Myxococcus xanthus cells to osmotic or high-temperature stress. J Bacteriol. 2006;188:823-8 pubmed
    A tBLASTn search of the Myxococcus xanthus genome database at The Institute for Genomic Research (TIGR) identified three genes (pdeA, pdeB, and pdeC) that encode proteins homologous to 3',5'-cyclic nucleotide phosphodiesterase...
  37. Piñar G, Jimenez Lopez C, Sterflinger K, Ettenauer J, Jroundi F, Fernandez Vivas A, et al. Bacterial community dynamics during the application of a Myxococcus xanthus-inoculated culture medium used for consolidation of ornamental limestone. Microb Ecol. 2010;60:15-28 pubmed publisher
    ..communities inhabiting quarry and decayed ornamental carbonate stones before and after the application of a Myxococcus xanthus-inoculated culture medium used for consolidation of the stones...
  38. Lee B, Schramm A, Jagadeesan S, Higgs P. Two-component systems and regulation of developmental progression in Myxococcus xanthus. Methods Enzymol. 2010;471:253-78 pubmed publisher
    b>Myxococcus xanthus is a prokaryotic model system for multicellular development and cell differentiation...
  39. White D, Hartzell P. AglU, a protein required for gliding motility and spore maturation of Myxococcus xanthus, is related to WD-repeat proteins. Mol Microbiol. 2000;36:662-78 pubmed
    The aglU gene of Myxococcus xanthus encodes a protein similar to Het-E1 (vegetative incompatibility) from Podospora anserina, acylaminoacyl-peptidase from Bacillus subtilis, and TolB from Escherichia coli...
  40. Kimura Y, Miyake R, Tokumasu Y, Sato M. Molecular cloning and characterization of two genes for the biotin carboxylase and carboxyltransferase subunits of acetyl coenzyme A carboxylase in Myxococcus xanthus. J Bacteriol. 2000;182:5462-9 pubmed
    We have cloned a DNA fragment from a genomic library of Myxococcus xanthus using an oligonucleotide probe representing conserved regions of biotin carboxylase subunits of acetyl coenzyme A (acetyl-CoA) carboxylases...
  41. Campoy S, Fontes M, Padmanabhan S, Cortés P, Llagostera M, Barbe J. LexA-independent DNA damage-mediated induction of gene expression in Myxococcus xanthus. Mol Microbiol. 2003;49:769-81 pubmed
    b>Myxococcus xanthus, a member of the Proteobacteria delta-class, has two independent recA genes, recA1 and recA2, but only recA2 is DNA damage-inducible. The lexA gene has been isolated from M...
  42. Gass J, Ehren J, Strohmeier G, Isaacs I, Khosla C. Fermentation, purification, formulation, and pharmacological evaluation of a prolyl endopeptidase from Myxococcus xanthus: implications for Celiac Sprue therapy. Biotechnol Bioeng. 2005;92:674-84 pubmed
    ..the in vitro gluten detoxifying properties of a therapeutically promising prolyl endopeptidase from Myxococcus xanthus (MX PEP), and describe the development of a prototypical enteric-coated capsule containing a ..
  43. Inclan Y, Laurent S, Zusman D. The receiver domain of FrzE, a CheA-CheY fusion protein, regulates the CheA histidine kinase activity and downstream signalling to the A- and S-motility systems of Myxococcus xanthus. Mol Microbiol. 2008;68:1328-39 pubmed publisher
    ..transduction pathway that controls cell reversals and directional movements for the two motility systems in Myxococcus xanthus. To trigger cell reversals, FrzE, a hybrid CheA-CheY fusion protein, autophosphorylates the kinase domain at ..
  44. Velicer G, Vos M. Sociobiology of the myxobacteria. Annu Rev Microbiol. 2009;63:599-623 pubmed publisher
    ..However, social harmony does not extend far. Spatially structured natural populations of the model species Myxococcus xanthus have fragmented into a large number of socially incompatible genotypes that exclude, exploit, and/or ..
  45. Giglio K, Caberoy N, Suen G, Kaiser D, Garza A. A cascade of coregulating enhancer binding proteins initiates and propagates a multicellular developmental program. Proc Natl Acad Sci U S A. 2011;108:E431-9 pubmed publisher
    ..Here, we report that Myxococcus xanthus regulates entry into its multicellular developmental program using a novel strategy: a cascade of ..
  46. Kimura Y, Yamashita S, Mori Y, Kitajima Y, Takegawa K. A Myxococcus xanthus bacterial tyrosine kinase, BtkA, is required for the formation of mature spores. J Bacteriol. 2011;193:5853-7 pubmed publisher
    A Myxococcus xanthus cytoplasmic bacterial tyrosine kinase, BtkA, showed phosphorylation activity in the presence of Exo. Phosphorylated BtkA was expressed late after starvation induction and early after glycerol induction...
  47. Bhat S, Zhu X, Patel R, Orlando R, Shimkets L. Identification and localization of Myxococcus xanthus porins and lipoproteins. PLoS ONE. 2011;6:e27475 pubmed publisher
    b>Myxococcus xanthus DK1622 contains inner (IM) and outer membranes (OM) separated by a peptidoglycan layer...
  48. Akiyama T, Inouye S, Komano T. Novel developmental genes, fruCD, of Myxococcus xanthus: involvement of a cell division protein in multicellular development. J Bacteriol. 2003;185:3317-24 pubmed
    b>Myxococcus xanthus is a gram-negative soil bacterium that undergoes multicellular development upon nutrient starvation. In the present study, two novel developmental genes, fruC and fruD, of M. xanthus were identified and characterized...
  49. Tzeng L, Singer M. DNA replication during sporulation in Myxococcus xanthus fruiting bodies. Proc Natl Acad Sci U S A. 2005;102:14428-33 pubmed
    During the developmental process of the Gram-negative soil bacterium Myxococcus xanthus, vegetatively growing rod cells differentiate to ultimately become metabolically quiescent and environmentally resistant myxospores encased within ..
  50. Higgs P, Cho K, Whitworth D, Evans L, Zusman D. Four unusual two-component signal transduction homologs, RedC to RedF, are necessary for timely development in Myxococcus xanthus. J Bacteriol. 2005;187:8191-5 pubmed
    ..a cluster of four two-component signal transduction genes that are necessary for proper progression of Myxococcus xanthus through development...
  51. Sliusarenko O, Neu J, Zusman D, Oster G. Accordion waves in Myxococcus xanthus. Proc Natl Acad Sci U S A. 2006;103:1534-9 pubmed
    b>Myxococcus xanthus are Gram-negative bacteria that glide on solid surfaces, periodically reversing their direction of movement. When starved, M...
  52. Youderian P, Hartzell P. Triple mutants uncover three new genes required for social motility in Myxococcus xanthus. Genetics. 2007;177:557-66 pubmed
    The bacterium Myxococcus xanthus glides over surfaces using two different locomotive mechanisms, called S (social) and A (adventurous) motility that enable cells to move both as groups and as individuals...
  53. Zhao J, Zhong L, Shen M, Xia Z, Cheng Q, Sun X, et al. Discovery of the autonomously replicating plasmid pMF1 from Myxococcus fulvus and development of a gene cloning system in Myxococcus xanthus. Appl Environ Microbiol. 2008;74:1980-7 pubmed publisher
    ..14, which encodes a large unknown protein, were shown to transform Myxococcus xanthus DZ1 and DK1622 at high frequencies ( approximately 10(5) CFU/microg DNA), suggesting that the locus is ..
  54. Pérez Marín M, Padmanabhan S, Polanco M, Murillo F, Elías Arnanz M. Vitamin B12 partners the CarH repressor to downregulate a photoinducible promoter in Myxococcus xanthus. Mol Microbiol. 2008;67:804-19 pubmed publisher
    A light-inducible promoter, P(B), drives expression of the carB operon in Myxococcus xanthus. Repressed by CarA in the dark, P(B) is activated when CarS, produced in the light, sequesters CarA to prevent operator-CarA binding...
  55. Hoiczyk E, Ring M, McHugh C, Schwär G, Bode E, Krug D, et al. Lipid body formation plays a central role in cell fate determination during developmental differentiation of Myxococcus xanthus. Mol Microbiol. 2009;74:497-517 pubmed publisher
    ..One example of prokaryotic differentiation is the gram-negative bacterium Myxococcus xanthus. In response to starvation, this gliding bacterium initiates a complex developmental programme that results ..
  56. García Moreno D, Abellón Ruiz J, García Heras F, Murillo F, Padmanabhan S, Elías Arnanz M. CdnL, a member of the large CarD-like family of bacterial proteins, is vital for Myxococcus xanthus and differs functionally from the global transcriptional regulator CarD. Nucleic Acids Res. 2010;38:4586-98 pubmed publisher
    CarD, a global transcriptional regulator in Myxococcus xanthus, interacts with CarG via CarDNter, its N-terminal domain, and with DNA via a eukaryotic HMGA-type C-terminal domain...
  57. Luciano J, Agrebi R, Le Gall A, Wartel M, Fiegna F, Ducret A, et al. Emergence and modular evolution of a novel motility machinery in bacteria. PLoS Genet. 2011;7:e1002268 pubmed publisher
    ..In the deltaproteobacterium Myxococcus xanthus, this locomotion allows the formation stress-resistant fruiting bodies where sporulation takes place...
  58. Gómez Santos N, Treuner Lange A, Moraleda Muñoz A, García Bravo E, García Hernández R, Martínez Cayuela M, et al. Comprehensive set of integrative plasmid vectors for copper-inducible gene expression in Myxococcus xanthus. Appl Environ Microbiol. 2012;78:2515-21 pubmed publisher
    b>Myxococcus xanthus is widely used as a model system for studying gliding motility, multicellular development, and cellular differentiation. Moreover, M. xanthus is a rich source of novel secondary metabolites...
  59. Pathak D, Wei X, Bucuvalas A, Haft D, Gerloff D, Wall D. Cell contact-dependent outer membrane exchange in myxobacteria: genetic determinants and mechanism. PLoS Genet. 2012;8:e1002626 pubmed publisher
    ..We further hypothesize that cell contact-dependent exchange helps myxobacteria to coordinate their social behaviors...
  60. Sarwar Z, Garza A. The Nla28S/Nla28 two-component signal transduction system regulates sporulation in Myxococcus xanthus. J Bacteriol. 2012;194:4698-708 pubmed publisher
    ..a cascade of transcriptional activators that modulates expression of many important developmental genes in Myxococcus xanthus. In this study, we identified and characterized Nla28S, a histidine kinase that modulates the activity of ..
  61. Wang Y, Zhang W, Zhang Z, Li J, Li Z, Tan Z, et al. Mechanisms involved in the functional divergence of duplicated GroEL chaperonins in Myxococcus xanthus DK1622. PLoS Genet. 2013;9:e1003306 pubmed publisher
    ..b>Myxococcus xanthus DK1622 has two copies of the groEL gene, each of which can be deleted without affecting cell viability; ..
  62. Welch R, Kaiser D. Cell behavior in traveling wave patterns of myxobacteria. Proc Natl Acad Sci U S A. 2001;98:14907-12 pubmed
    ..This last behavior is unique to a rippling population and, on the basis of Myxococcus xanthus genetic data, we conclude that this periodicity is linked to the C signal, a nondiffusible cell contact-..
  63. Browning D, Whitworth D, Hodgson D. Light-induced carotenogenesis in Myxococcus xanthus: functional characterization of the ECF sigma factor CarQ and antisigma factor CarR. Mol Microbiol. 2003;48:237-51 pubmed
    Illumination of dark-grown Myxococcus xanthus with blue light leads to the induction of carotenoid synthesis...
  64. Li Y, Sun H, Ma X, Lu A, Lux R, Zusman D, et al. Extracellular polysaccharides mediate pilus retraction during social motility of Myxococcus xanthus. Proc Natl Acad Sci U S A. 2003;100:5443-8 pubmed
    b>Myxococcus xanthus is a Gram-negative bacterium with a complex life cycle that includes vegetative swarming and fruiting-body formation...
  65. Fiegna F, Velicer G. Competitive fates of bacterial social parasites: persistence and self-induced extinction of Myxococcus xanthus cheaters. Proc Biol Sci. 2003;270:1527-34 pubmed
    Cooperative biological systems are susceptible to disruption by cheating. Using the social bacterium Myxococcus xanthus, we have tested the short-term competitive fates of mixed cheater and wild-type strains over multiple cycles of ..
  66. Inclan Y, Vlamakis H, Zusman D. FrzZ, a dual CheY-like response regulator, functions as an output for the Frz chemosensory pathway of Myxococcus xanthus. Mol Microbiol. 2007;65:90-102 pubmed
    b>Myxococcus xanthus utilizes two distinct motility systems for movement (gliding) on solid surfaces: adventurous motility (A-motility) and social motility (S-motility)...
  67. Shi X, Wegener Feldbrügge S, Huntley S, Hamann N, Hedderich R, Søgaard Andersen L. Bioinformatics and experimental analysis of proteins of two-component systems in Myxococcus xanthus. J Bacteriol. 2008;190:613-24 pubmed
    ..Accordingly, in Myxococcus xanthus, TCS are important for normal motility and fruiting body formation and sporulation. Here we analyzed the M...
  68. Vos M, Velicer G. Isolation by distance in the spore-forming soil bacterium Myxococcus xanthus. Curr Biol. 2008;18:386-91 pubmed publisher
    ..b>Myxococcus xanthus is a globally distributed, spore-forming bacterium that offers a robust test for genetic differentiation ..
  69. Hu W, Hossain M, Lux R, Wang J, Yang Z, Li Y, et al. Exopolysaccharide-independent social motility of Myxococcus xanthus. PLoS ONE. 2011;6:e16102 pubmed publisher
    Social motility (S motility), the coordinated movement of large cell groups on agar surfaces, of Myxococcus xanthus requires type IV pili (TFP) and exopolysaccharides (EPS)...
  70. Remis J, Wei D, Gorur A, Zemla M, Haraga J, Allen S, et al. Bacterial social networks: structure and composition of Myxococcus xanthus outer membrane vesicle chains. Environ Microbiol. 2014;16:598-610 pubmed publisher
    The social soil bacterium, Myxococcus xanthus, displays a variety of complex and highly coordinated behaviours, including social motility, predatory rippling and fruiting body formation. Here we show that M...
  71. Kimura Y, Mishima Y, Nakano H, Takegawa K. An adenylyl cyclase, CyaA, of Myxococcus xanthus functions in signal transduction during osmotic stress. J Bacteriol. 2002;184:3578-85 pubmed
    An adenylyl cyclase gene (cyaA) present upstream of an osmosensor protein gene (mokA) was isolated from Myxococcus xanthus. cyaA encoded a polypeptide of 843 amino acids with a predicted molecular mass of 91,187 Da...