ureaplasma urealyticum

Summary

Summary: A species of gram-negative bacteria found in the human genitourinary tract (UROGENITAL SYSTEM), oropharynx, and anal canal. Serovars 1, 3, 6, and 14 have been reclassed into a separate species UREAPLASMA parvum.

Top Publications

  1. van der Schee C, Sluiters H, van der Meijden W, van Beek P, Peerbooms P, Verbrugh H, et al. Host and pathogen interaction during vaginal infection by Trichomonas vaginalis and Mycoplasma hominis or Ureaplasma urealyticum. J Microbiol Methods. 2001;45:61-7 pubmed
    ..Since M. hominis and Ureaplasma urealyticum are similar pathogens, both belonging to the class of the mycoplasmata, we describe here a molecular study ..
  2. Judlin P. [Genital mycoplasmas]. Gynecol Obstet Fertil. 2003;31:954-9 pubmed
    ..On the other hand, M. genitalium has been much less studied but it seems to be an unquestionable pathogen of genital tract; new studies will be necessary so that one has a better understanding of the pathologies it can induce...
  3. Rosemond A, Lanotte P, Watt S, Sauget A, Guerif F, Royere D, et al. [Systematic screening tests for Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum in urogenital specimens of infertile couples]. Pathol Biol (Paris). 2006;54:125-9 pubmed
    ..determine if there is a benefit for systematic screening of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum among genito-urinary specimen when exploring couples infertility. C...
  4. Cakan H, Polat E, Kocazeybek B, Ocal P, Cepni I, Aslan M, et al. Assessment of antibiotic susceptibility of Ureaplasma urealyticum from prostitutes and outpatient clinic patients using the E-test and agar dilution method. Chemotherapy. 2003;49:39-43 pubmed
    In this study, a total of 647 vaginal discharge samples were examined. Ureaplasma urealyticum growth was seen in 68 samples (10.5%). The antibiotic sensitivity of 30 types of U...
  5. Jensen A, Kleveland C, Moghaddam A, Haaheim H, Hjelmevoll S, Skogen V. Chlamydia trachomatis, Mycoplasma genitalium and Ureaplasma urealyticum among students in northern Norway. J Eur Acad Dermatol Venereol. 2013;27:e91-6 pubmed publisher
    ..urealyticum and C. trachomatis. U. urealyticum appeared more prevalent than C. trachomatis and increased number of sexual partners was associated with increased risk of a positive test. M. genitalium had a low prevalence. ..
  6. Matlow A, Th ng C, Kovach D, Quinn P, Dunn M, Wang E. Susceptibilities of neonatal respiratory isolates of Ureaplasma urealyticum to antimicrobial agents. Antimicrob Agents Chemother. 1998;42:1290-2 pubmed
    Twenty-one neonatal respiratory isolates of Ureaplasma urealyticum were serotyped, and their susceptibilities to ciprofloxacin, gentamicin, chloramphenicol, erythromycin, azithromycin, and doxycycline were tested...
  7. Kirchner L, Helmer H, Heinze G, Wald M, Brunbauer M, Weninger M, et al. Amnionitis with Ureaplasma urealyticum or other microbes leads to increased morbidity and prolonged hospitalization in very low birth weight infants. Eur J Obstet Gynecol Reprod Biol. 2007;134:44-50 pubmed
    ..To investigate the influence of culture proven intrauterine infection on preterm morbidity and to test the effect of antimicrobial treatment...
  8. Kosinska U, Carnrot C, Eriksson S, Wang L, Eklund H. Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme. FEBS J. 2005;272:6365-72 pubmed
    Thymidine kinases have been found in most organisms, from viruses and bacteria to mammals. Ureaplasma urealyticum (parvum), which belongs to the class of cell-wall-lacking Mollicutes, has no de novo synthesis of DNA precursors and ..
  9. Goldenberg R, Andrews W, Goepfert A, Faye Petersen O, Cliver S, Carlo W, et al. The Alabama Preterm Birth Study: umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants. Am J Obstet Gynecol. 2008;198:43.e1-5 pubmed publisher
    This study was undertaken to evaluate the frequency of umbilical cord blood infections with Ureaplasma urealyticum and Mycoplasma hominis in preterm 23- to 32-week births and to determine their association with various obstetric ..

More Information

Publications92

  1. Wang Y, Liang C, Wu J, Xu C, Qin S, Gao E. Do Ureaplasma urealyticum infections in the genital tract affect semen quality?. Asian J Androl. 2006;8:562-8 pubmed
    To investigate the relationship between Ureaplasma urealyticum (UU) infection and semen quality.
  2. Tang J, Zhou L, Liu X, Zhang C, Zhao Y, Wang Y. Novel multiplex real-time PCR system using the SNP technology for the simultaneous diagnosis of Chlamydia trachomatis, Ureaplasma parvum and Ureaplasma urealyticum and genetic typing of serovars of C. trachomatis and U. parvum in NGU. Mol Cell Probes. 2011;25:55-9 pubmed publisher
    ..real-time PCR system for the simultaneous diagnosis of Chlamydia trachomatis, Ureaplasma parvum and Ureaplasma urealyticum and molecular detection of serovars of C. trachomatis and U...
  3. Horner P, Thomas B, Gilroy C, Egger M, Taylor Robinson D. Role of Mycoplasma genitalium and Ureaplasma urealyticum in acute and chronic nongonococcal urethritis. Clin Infect Dis. 2001;32:995-1003 pubmed
    ..014). Ureaplasmas or M. genitalium were associated with both chronic NGU, which was defined as urethritis that occurred 30-92 days after the commencement of treatment (P=.028), and chronic NGU with symptoms or signs (P=.005). ..
  4. Povlsen K, Jensen J, Lind I. Detection of Ureaplasma urealyticum by PCR and biovar determination by liquid hybridization. J Clin Microbiol. 1998;36:3211-6 pubmed
    An assay which combines the direct detection of Ureaplasma urealyticum with biovar determination was developed and applied to 618 urogenital specimens. U. urealyticum was detected by inhibitor-controlled PCR...
  5. Capoccia R, Greub G, Baud D. Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes. Curr Opin Infect Dis. 2013;26:231-40 pubmed publisher
    Mycoplasma hominis and Ureaplasma urealyticum may colonize the human genital tract and have been associated with adverse pregnancy outcomes...
  6. Maeda S, Tamaki M, Kubota Y, Nguyen P, Yasuda M, Deguchi T. Treatment of men with urethritis negative for Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum. Int J Urol. 2007;14:422-5 pubmed
    ..trachomatis-positive NGU have been performed. We assessed the efficacy of antimicrobial agents that are active against C. trachomatis on non-mycoplasmal, non-ureaplasmal and non-chlamydial NGU (NMNUNCNGU)...
  7. Egawa T, Morioka I, Morisawa T, Yokoyama N, Nakao H, Ohashi M, et al. Ureaplasma urealyticum and Mycoplasma hominis presence in umbilical cord is associated with pathogenesis of funisitis. Kobe J Med Sci. 2007;53:241-9 pubmed
    b>Ureaplasma urealyticum (U. urealyticum) and Mycoplasma hominis (M...
  8. Zdrodowska Stefanow B, Kłosowska W, Ostaszewska Puchalska I, Bułhak Kozioł V, Kotowicz B. Ureaplasma urealyticum and Mycoplasma hominis infection in women with urogenital diseases. Adv Med Sci. 2006;51:250-3 pubmed
    The aim of the study was to assess the incidence of Ureaplasma urealyticum (U. urealyticum) and Mycoplasma hominis (M. hominis) infection in women with urogenital diseases.
  9. Yager J, Ford E, Boas Z, Haseley L, Cookson B, Sengupta D, et al. Ureaplasma urealyticum continuous ambulatory peritoneal dialysis-associated peritonitis diagnosed by 16S rRNA gene PCR. J Clin Microbiol. 2010;48:4310-2 pubmed publisher
    ..We report a case of Ureaplasma urealyticum CAPD-associated peritonitis diagnosed by 16S rRNA gene PCR...
  10. Kacerovsky M, Boudys L. [Preterm premature rupture of membranes and Ureaplasma urealyticum]. Ceska Gynekol. 2008;73:154-9 pubmed
    ..Control group 3 were women with normal pregnancy. Ureaplasma urealyticum was detected in 96% (72/75) of the patients with PPROM between 24 and 34 weeks of gestation and in 32% (24/..
  11. Monecke S, Helbig J, Jacobs E. Phase variation of the multiple banded protein in Ureaplasma urealyticum and Ureaplasma parvum. Int J Med Microbiol. 2003;293:203-11 pubmed
    b>Ureaplasma urealyticum and U. parvum are common commensals and, possibly, pathogens of the human urogenital tract. Like other Mycoplasmatales they possess variable surface proteins...
  12. Vogel I, Thorsen P, Hogan V, Schieve L, Jacobsson B, Ferre C. The joint effect of vaginal Ureaplasma urealyticum and bacterial vaginosis on adverse pregnancy outcomes. Acta Obstet Gynecol Scand. 2006;85:778-85 pubmed
    To examine associations of vaginal Ureaplasma urealyticum (UU) and bacterial vaginosis (BV) with preterm delivery (PTD), small for gestational age (SGA), and low birth weight (LBW)...
  13. Manimtim W, Hasday J, Hester L, Fairchild K, Lovchik J, Viscardi R. Ureaplasma urealyticum modulates endotoxin-induced cytokine release by human monocytes derived from preterm and term newborns and adults. Infect Immun. 2001;69:3906-15 pubmed
    We previously observed that Ureaplasma urealyticum respiratory tract colonization in infants with a birth weight of < or =1,250 g was associated with increases in the tracheal aspirate proinflammatory cytokines tumor necrosis factor ..
  14. Kim M, Kim G, Romero R, Shim S, Kim E, Yoon B. Biovar diversity of Ureaplasma urealyticum in amniotic fluid: distribution, intrauterine inflammatory response and pregnancy outcomes. J Perinat Med. 2003;31:146-52 pubmed
    The objective of this study was to determine the distribution of two biovars of Ureaplasma urealyticum (parvo and T960) in human amniotic fluid and to examine whether the magnitude of the intrauterine inflammatory response and pregnancy ..
  15. Robertson J, Stemke G, Davis J, Harasawa R, Thirkell D, Kong F, et al. Proposal of Ureaplasma parvum sp. nov. and emended description of Ureaplasma urealyticum (Shepard et al. 1974) Robertson et al. 2001. Int J Syst Evol Microbiol. 2002;52:587-97 pubmed
    The phenotypic and genotypic properties of Ureaplasma urealyticum (family Mycoplasmataceae, order Mycoplasmatales, class Mollicutes) are reviewed here...
  16. Katz B, Patel P, Duffy L, Schelonka R, Dimmitt R, Waites K. Characterization of ureaplasmas isolated from preterm infants with and without bronchopulmonary dysplasia. J Clin Microbiol. 2005;43:4852-4 pubmed
    ..urealyticum. U. parvum was detected more often than U. urealyticum. There was no significant difference or trend in the prevalence of either species between infants with or without bronchopulmonary dysplasia when isolated alone...
  17. Viscardi R, Manimtim W, Sun C, Duffy L, Cassell G. Lung pathology in premature infants with Ureaplasma urealyticum infection. Pediatr Dev Pathol. 2002;5:141-50 pubmed
    Respiratory tract colonization with Ureaplasma urealyticum in preterm infants has been associated with a higher incidence of pneumonia, severe respiratory failure, bronchopulmonary dysplasia (BPD), and death...
  18. Lukic A, Canzio C, Patella A, Giovagnoli M, Cipriani P, Frega A, et al. Determination of cervicovaginal microorganisms in women with abnormal cervical cytology: the role of Ureaplasma urealyticum. Anticancer Res. 2006;26:4843-9 pubmed
  19. Zeighami H, Peerayeh S, Safarlu M. Detection of Ureaplasma urealyticum in semen of infertile men by PCR. Pak J Biol Sci. 2007;10:3960-3 pubmed
    b>Ureaplasma urealyticum is a causative agent ofnon-gonococcal urethritis, prostatitis, epididymitis and infertility. The organism is more common in partners of infertile than fertile marriages. U...
  20. Li R, Xi Y, Liu X, Chen G, Wang B, Jiang L, et al. Expression of IL-1alpha, IL-6, TGF-beta, FasL and ZNF265 during sertoli cell infection by ureaplasma urealyticum. Cell Mol Immunol. 2009;6:215-21 pubmed publisher
    ..mechanisms of Sertoli cells in the testis in vitro and in vivo, we utilized our well-characterized Ureaplasma Urealyticum (UU)-induced model...
  21. Onderdonk A, Delaney M, Dubois A, Allred E, Leviton A. Detection of bacteria in placental tissues obtained from extremely low gestational age neonates. Am J Obstet Gynecol. 2008;198:110.e1-7 pubmed publisher
    ..Approximately half of second-trimester placentas harbor organisms within the chorionic plate. The chorion parenchyma appears to harbor constituents that prevent the identification of bacterial deoxyribonucleic acid by PCR methods. ..
  22. Rodríguez N, Fernandez C, Zamora Y, Berdasquera D, Rivera J. Detection of Ureaplasma urealyticum and Ureaplasma parvum in amniotic fluid: association with pregnancy outcomes. J Matern Fetal Neonatal Med. 2011;24:47-50 pubmed publisher
    b>Ureaplasma urealyticum is one of the organisms most frequently isolated from the amniotic fluid of women with adverse pregnancy. The prevalence of U. urealyticum and U...
  23. Casari E, Ferrario A, Morenghi E, Montanelli A. Gardnerella, Trichomonas vaginalis, Candida, Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum in the genital discharge of symptomatic fertile and asymptomatic infertile women. New Microbiol. 2010;33:69-76 pubmed
  24. Shimada Y, Ito S, Mizutani K, Sugawara T, Seike K, Tsuchiya T, et al. Bacterial loads of Ureaplasma urealyticum contribute to development of urethritis in men. Int J STD AIDS. 2014;25:294-8 pubmed publisher
    b>Ureaplasma urealyticum could be a pathogen of non-gonococcal urethritis (NGU) in men. However, ureaplasma is often detected in men without NGU, and the proportion of cases possibly attributable to this pathogen is still undefined...
  25. Kotecha S, Hodge R, Schaber J, Miralles R, Silverman M, Grant W. Pulmonary Ureaplasma urealyticum is associated with the development of acute lung inflammation and chronic lung disease in preterm infants. Pediatr Res. 2004;55:61-8 pubmed
    ..We revisited these infants who did not have clinical or laboratory evidence of infection and searched for Ureaplasma urealyticum, group B streptococci, and other microbes by reverse transcription-PCR performed on RNA extracted from 93 ..
  26. Mallard K, Schopfer K, Bodmer T. Development of real-time PCR for the differential detection and quantification of Ureaplasma urealyticum and Ureaplasma parvum. J Microbiol Methods. 2005;60:13-9 pubmed
    Ureaplasma parvum and Ureaplasma urealyticum are recently recognized species of the genus Ureaplasma. In humans, Ureaplasma spp. can be found on mucosal surfaces, primarily in the respiratory and urogenital tracts...
  27. Baier R, Loggins J, Kruger T. Monocyte chemoattractant protein-1 and interleukin-8 are increased in bronchopulmonary dysplasia: relation to isolation of Ureaplasma urealyticum. J Investig Med. 2001;49:362-9 pubmed
    ..b>Ureaplasma urealyticum (Uu) is frequently isolated from cultures of tracheal secretions obtained from very low birth weight ..
  28. Yi J, Yoon B, Kim E. Detection and biovar discrimination of Ureaplasma urealyticum by real-time PCR. Mol Cell Probes. 2005;19:255-60 pubmed
    Prenatal intrauterine infection has been recognized as an important cause of premature birth, and Ureaplasma urealyticum is one of the commonest pathogens. U...
  29. Peltier M, Freeman A, Mu H, Cole B. Characterization of the macrophage-stimulating activity from Ureaplasma urealyticum. Am J Reprod Immunol. 2007;57:186-92 pubmed
    ..The majority of intrauterine infections, however, are associated with Ureaplasma urealyticum, which does not contain LPS...
  30. Cordtz J, Jensen J. Disseminated Ureaplasma urealyticum infection in a hypo-gammaglobulinaemic renal transplant patient. Scand J Infect Dis. 2006;38:1114-7 pubmed
    ..Routine microbiological tests were negative. Six weeks after admission, abscess material was grown on Mycoplasma culture medium yielding U. urealyticum in high titres. The patient responded promptly to appropriate antibiotics...
  31. Lee J, Kim K, Lee H, Yang K, Seo J, Choe J. Concordance of Ureaplasma urealyticum and Mycoplasma hominis in infertile couples: impact on semen parameters. Urology. 2013;81:1219-24 pubmed publisher
    ..the relationship between mycoplasma infection and human infertility, we determined the concordance of Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) detection in infertile and fertile couples, and assessed semen parameters ..
  32. Deguchi T, Yoshida T, Miyazawa T, Yasuda M, Tamaki M, Ishiko H, et al. Association of Ureaplasma urealyticum (biovar 2) with nongonococcal urethritis. Sex Transm Dis. 2004;31:192-5 pubmed
    The tiny (T)-strain mycoplasmas, designated in 1974 as Ureaplasma urealyticum, have been divided into 2 species, Ureaplasma parvum (biovar 1) and U...
  33. García de la Fuente C, Minambres E, Ugalde E, Saez A, Martinez Martinez L, Farinas M. Post-operative mediastinitis, pleuritis and pericarditis due to Mycoplasma hominis and Ureaplasma urealyticum with a fatal outcome. J Med Microbiol. 2008;57:656-7 pubmed publisher
    ..We report an unusual case of Mycoplasma hominis and Ureaplasma urealyticum post-surgical mediastinitis with persistent pleural and pericardial effusion...
  34. Verteramo R, Pierangeli A, Mancini E, Calzolari E, Bucci M, Osborn J, et al. Human Papillomaviruses and genital co-infections in gynaecological outpatients. BMC Infect Dis. 2009;9:16 pubmed publisher
    ..High grade HPV infections and persistence are the strongest risk factors for cervical cancer. Nevertheless other genital microorganisms may be involved in the progression of HPV associated lesions...
  35. Vancutsem E, Soetens O, Breugelmans M, Foulon W, Naessens A. Modified real-time PCR for detecting, differentiating, and quantifying Ureaplasma urealyticum and Ureaplasma parvum. J Mol Diagn. 2011;13:206-12 pubmed publisher
    ..5 × 10(3) to 7.4 × 10(7) copies per specimen. In conclusion, the modified qPCR is a suitable method for rapid detection, differentiation, and quantification of U. parvum and U. urealyticum...
  36. Pinna G, Skevaki C, Kafetzis D. The significance of Ureaplasma urealyticum as a pathogenic agent in the paediatric population. Curr Opin Infect Dis. 2006;19:283-9 pubmed
    b>Ureaplasma urealyticum is a frequent commensal in the lower genital tract of sexually active women. It may be transmitted perinatally from the colonized mother to her offspring, often resulting in prematurity and neonatal disease...
  37. Yokoi S, Maeda S, Kubota Y, Tamaki M, Mizutani K, Yasuda M, et al. The role of Mycoplasma genitalium and Ureaplasma urealyticum biovar 2 in postgonococcal urethritis. Clin Infect Dis. 2007;45:866-71 pubmed
    ..Thus, we conducted a study to determine the prevalence of coinfection with genital mycoplasmas and ureaplasmas among men with GU and to assess the role of these pathogens in PGU...
  38. Waites K, Duffy L, Bébéar C, Matlow A, Talkington D, Kenny G, et al. Standardized methods and quality control limits for agar and broth microdilution susceptibility testing of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum. J Clin Microbiol. 2012;50:3542-7 pubmed publisher
    ..quality control of antimicrobial susceptibility testing of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum using broth microdilution and agar dilution techniques...
  39. Pollack J. Ureaplasma urealyticum: an opportunity for combinatorial genomics. Trends Microbiol. 2001;9:169-75 pubmed
    ..The newly sequenced genome of Ureaplasma urealyticum (parvum) is another prokaryote example of the class Mollicutes where such confounding differences are ..
  40. Carnrot C, Wehelie R, Eriksson S, Bölske G, Wang L. Molecular characterization of thymidine kinase from Ureaplasma urealyticum: nucleoside analogues as potent inhibitors of mycoplasma growth. Mol Microbiol. 2003;50:771-80 pubmed
    b>Ureaplasma urealyticum (U. urealyticum), belonging to the class Mollicutes, is a human pathogen colonizing the urogenital tract and causes among other things respiratory diseases in premature infants...
  41. Pandey A, Dhawan B, Gupta V, Chaudhry R, Deorari A. Clinical significance of airways colonization with Ureaplasma urealyticum in premature (<34 wk) neonates. Indian J Med Res. 2007;125:679-84 pubmed
    b>Ureaplasma urealyticum has been implicated in various neonatal morbidities in preterm infants. Its association with chronic lung disease (CLD) remains controversial. The aim of this prospective study was to investigate colonization of U...
  42. Lee S, Romero R, Kim E, Yoon B. A high Nugent score but not a positive culture for genital mycoplasmas is a risk factor for spontaneous preterm birth. J Matern Fetal Neonatal Med. 2009;22:212-7 pubmed publisher
    ..This study was performed to evaluate the relationship among the Nugent score for the diagnosis of bacterial vaginosis (BV), the results of vaginal fluid culture for genital mycoplasmas, and the subsequent occurrence of preterm birth...
  43. Viscardi R, Atamas S, Luzina I, Hasday J, He J, Sime P, et al. Antenatal Ureaplasma urealyticum respiratory tract infection stimulates proinflammatory, profibrotic responses in the preterm baboon lung. Pediatr Res. 2006;60:141-6 pubmed
    ..Collectively, these data suggest that a prolonged proinflammatory response initiated by intrauterine Ureaplasma infection contributes to early fibrosis and altered developmental signaling in the immature lung...
  44. Yoshida T, Maeda S, Deguchi T, Miyazawa T, Ishiko H. Rapid detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum organisms in genitourinary samples by PCR-microtiter plate hybridization assay. J Clin Microbiol. 2003;41:1850-5 pubmed
    ..a method for detecting the presence of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum organisms, which are thought to be associated with nongonococcal urethritis (NGU) and other genitourinary ..
  45. Chung H, Chung J, Chun S, Sung H, Kim M, Kim K. [A case of erythromycin-resistant Ureaplasma urealyticum meningitis in a premature infant]. Korean J Lab Med. 2007;27:46-9 pubmed
    b>Ureaplasma urealyticum causes infection or colonization of female genital tracts associated with preterm delivery and infertility and the infection of the bloodstream, respiratory tract, and central nervous system in infants, especially ..
  46. Shi J, Yang Z, Wang M, Cheng G, Li D, Wang Y, et al. Screening of an antigen target for immunocontraceptives from cross-reactive antigens between human sperm and Ureaplasma urealyticum. Infect Immun. 2007;75:2004-11 pubmed
    Epidemiologic studies indicated that some infertile men who were infected with Ureaplasma urealyticum displayed positive antisperm antibodies in their serum and/or semen...
  47. Ozdemir R, Erdeve O, Dizdar E, Oguz S, Uras N, Saygan S, et al. Clarithromycin in preventing bronchopulmonary dysplasia in Ureaplasma urealyticum-positive preterm infants. Pediatrics. 2011;128:e1496-501 pubmed publisher
    To evaluate the efficacy and safety of clarithromycin treatment in preventing bronchopulmonary dysplasia (BPD) in Ureaplasma urealyticum-positive preterm infants.
  48. Bebear C, Renaudin H, Charron A, Gruson D, Lefrancois M, Bebear C. In vitro activity of trovafloxacin compared to those of five antimicrobials against mycoplasmas including Mycoplasma hominis and Ureaplasma urealyticum fluoroquinolone-resistant isolates that have been genetically characterized. Antimicrob Agents Chemother. 2000;44:2557-60 pubmed
    The in vitro activity of trovafloxacin against 125 strains of Mycoplasma species and Ureaplasma urealyticum, including fluoroquinolone-susceptible and fluoroquinolone-resistant species, was compared to those of other fluoroquinolones, ..
  49. Wehelie R, Eriksson S, Wang L. Effect of fluoropyrimidines on the growth of Ureaplasma urealyticum. Nucleosides Nucleotides Nucleic Acids. 2004;23:1499-502 pubmed
    In the present study, we investigated the effect of fluoropyrimidines on the growth of Ureaplasma urealyticum. Addition of fluoropyrimidines strongly inhibited bacterial growth...
  50. Eilers E, Moter A, Bollmann R, Haffner D, Querfeld U. Intrarenal abscesses due to Ureaplasma urealyticum in a transplanted kidney. J Clin Microbiol. 2007;45:1066-8 pubmed
    ..Amplification of the 16S rRNA gene with subsequent sequencing revealed Ureaplasma urealyticum as the infectious agent...
  51. Waites K, Katz B, Schelonka R. Mycoplasmas and ureaplasmas as neonatal pathogens. Clin Microbiol Rev. 2005;18:757-89 pubmed
  52. Biernat Sudolska M, Rojek Zakrzewska D, Rzepecka Weglarz B, Woźniak J, Lauterbach R. [Influence of ureaplasma infection on the clinical state of newborns]. Przegl Epidemiol. 2006;60:53-8 pubmed
    ..The aim of this study was the analysis of the clinical state of newborns infected with various species of ureaplasma...
  53. Andrade Rocha F. Ureaplasma urealyticum and Mycoplasma hominis in men attending for routine semen analysis. Prevalence, incidence by age and clinical settings, influence on sperm characteristics, relationship with the leukocyte count and clinical value. Urol Int. 2003;71:377-81 pubmed
    To investigate the clinical value of the screening of Ureaplasma urealyticum and Mycoplasma hominis in routine semen analysis.
  54. Baka S, Kouskouni E, Antonopoulou S, Sioutis D, Papakonstantinou M, Hassiakos D, et al. Prevalence of Ureaplasma urealyticum and Mycoplasma hominis in women with chronic urinary symptoms. Urology. 2009;74:62-6 pubmed publisher
    To assess the prevalence of Ureaplasma urealyticum and Mycoplasma hominis in women experiencing chronic urinary symptoms.
  55. Maeda S, Deguchi T, Ishiko H, Matsumoto T, Naito S, Kumon H, et al. Detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum (biovar 1) and Ureaplasma urealyticum (biovar 2) in patients with non-gonococcal urethritis using polymerase chain reaction-microtiter plate hybridization. Int J Urol. 2004;11:750-4 pubmed
    ..plate hybridization assays to detect Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum (biovar 1) and Ureaplasma urealyticum (biovar 2) in first-voided urine specimens from patients with non-gonococcal urethritis (NGU).
  56. Harada K, Tanaka H, Komori S, Tsuji Y, Nagata K, Tsutsui H, et al. Vaginal infection with Ureaplasma urealyticum accounts for preterm delivery via induction of inflammatory responses. Microbiol Immunol. 2008;52:297-304 pubmed publisher
    ..These results suggest that U. urealyticum infection might play a causative role in preterm delivery via LP-induced IL-8 production and apoptosis...
  57. Diaz N, Dessi D, Dessole S, Fiori P, Rappelli P. Rapid detection of coinfections by Trichomonas vaginalis, Mycoplasma hominis, and Ureaplasma urealyticum by a new multiplex polymerase chain reaction. Diagn Microbiol Infect Dis. 2010;67:30-6 pubmed publisher
    ..chain reaction (M-PCR) assay to simultaneously detect Trichomonas vaginalis, Mycoplasma hominis, and Ureaplasma urealyticum. The test is extremely specific and has a sensitivity of 10 cells for T. vaginalis and U...
  58. Yoon B, Romero R, Lim J, Shim S, Hong J, Shim J, et al. The clinical significance of detecting Ureaplasma urealyticum by the polymerase chain reaction in the amniotic fluid of patients with preterm labor. Am J Obstet Gynecol. 2003;189:919-24 pubmed
    This study was undertaken to determine the clinical significance of a detection of Ureaplasma urealyticum by using the polymerase chain reaction (PCR) in the amniotic fluid of patients with preterm labor and intact membranes.
  59. Rastawicki W, Kalota H, Jagielski M, Gierczyński R. [Comparison of polymerase chain reaction assay and Mycoplasma IST 2 test with culture for detection of infections caused by Ureaplasma urealyticum and Mycoplasma hominis]. Med Dosw Mikrobiol. 2004;56:99-108 pubmed
    ..0%) for U. urealyticum in PCR and Mycoplasma IST 2 test. The discrepancy of results obtained in Mycoplasma IST 2 test and culture as well as in PCR may suggest the over sensitivity of the commercial test for detection of M. hominis...
  60. Salmeri M, Valenti D, La Vignera S, Bellanca S, Morello A, Toscano M, et al. Prevalence of Ureaplasma urealyticum and Mycoplasma hominis infection in unselected infertile men. J Chemother. 2012;24:81-6 pubmed publisher
    In this study, we investigated the prevalence of Ureaplasma urealyticum and Mycoplasma hominis infection among 250 unselected infertile men, the presence of urogenital symptoms in infected men and the effects of these microorganisms on ..
  61. Lanzafame M, Delama A, Lattuada E, Faggian F, Padovani G, Concia E, et al. Prevalence and clinical significance of Ureaplasma urealyticum and Mycoplasma hominis in the lower genital tract of HIV-1-infected women. Infez Med. 2006;14:213-5 pubmed
    Mycoplasma hominis and Ureaplasma urealyticum are frequently isolated from the cervical and vaginal tracts of HIV-negative asymptomatic women...
  62. Hassan S, Romero R, Hendler I, Gomez R, Khalek N, Espinoza J, et al. A sonographic short cervix as the only clinical manifestation of intra-amniotic infection. J Perinat Med. 2006;34:13-9 pubmed
    ..This study was conducted to determine the rate of MIAC and intra-amniotic inflammation in patients with a cervical length < 25 mm in the mid-trimester...
  63. Bayraktar M, Ozerol I, Gucluer N, Celik O. Prevalence and antibiotic susceptibility of Mycoplasma hominis and Ureaplasma urealyticum in pregnant women. Int J Infect Dis. 2010;14:e90-5 pubmed publisher
    Mycoplasma hominis and Ureaplasma urealyticum are important opportunistic pathogens implicated in urogenital infections and complicated pregnancy...
  64. Olomu I, Hecht J, Onderdonk A, Allred E, Leviton A. Perinatal correlates of Ureaplasma urealyticum in placenta parenchyma of singleton pregnancies that end before 28 weeks of gestation. Pediatrics. 2009;123:1329-36 pubmed publisher
    The purpose of this work was to examine the relationship between Ureaplasma urealyticum in the placenta and perinatal outcomes in extreme preterm deliveries and to explore the influence of bacteria coinfection on perinatal outcomes in U ..
  65. Honma Y, Yada Y, Takahashi N, Momoi M, Nakamura Y. Certain type of chronic lung disease of newborns is associated with Ureaplasma urealyticum infection in utero. Pediatr Int. 2007;49:479-84 pubmed
    ..However, the association of Ureaplasma urealyticum infection and CLD has been controversial. The purpose of the present paper was to determine whether U...
  66. Heggie A, Bar Shain D, Boxerbaum B, Fanaroff A, O Riordan M, Robertson J. Identification and quantification of ureaplasmas colonizing the respiratory tract and assessment of their role in the development of chronic lung disease in preterm infants. Pediatr Infect Dis J. 2001;20:854-9 pubmed
    The role of Ureaplasma urealyticum in the development of chronic lung disease (CLD) in preterm infants continues to be disputed. Recently U. urealyticum has been found to consist of two species, U...
  67. Castro Alcaraz S, Greenberg E, Bateman D, Regan J. Patterns of colonization with Ureaplasma urealyticum during neonatal intensive care unit hospitalizations of very low birth weight infants and the development of chronic lung disease. Pediatrics. 2002;110:e45 pubmed
    b>Ureaplasma urealyticum and its association with chronic lung disease (CLD) of prematurity has remained a controversial topic...
  68. Karabay O, Topcuoglu A, Kocoglu E, Gurel S, Gurel H, Ince N. Prevalence and antibiotic susceptibility of genital Mycoplasma hominis and Ureaplasma urealyticum in a university hospital in Turkey. Clin Exp Obstet Gynecol. 2006;33:36-8 pubmed
    This study aimed to assess the colonization prevalence and antibiotic susceptibility of genital Ureaplasma urealyticum and Mycoplasma hominis in a teaching hospital, in Turkey...
  69. Yoshida T, Deguchi T, Meda S, Kubota Y, Tamaki M, Yokoi S, et al. Quantitative detection of Ureaplasma parvum (biovar 1) and Ureaplasma urealyticum (biovar 2) in urine specimens from men with and without urethritis by real-time polymerase chain reaction. Sex Transm Dis. 2007;34:416-9 pubmed
    We previously reported a significant association between Ureaplasma urealyticum (biovar 2) and nongonococcal urethritis (NGU)...
  70. Wetmore C, Manhart L, Lowens M, Golden M, Jensen N, Astete S, et al. Ureaplasma urealyticum is associated with nongonococcal urethritis among men with fewer lifetime sexual partners: a case-control study. J Infect Dis. 2011;204:1274-82 pubmed publisher
    ..We evaluated the association of the newly differentiated species Ureaplasma urealyticum (UU) and Ureaplasma parvum (UP) with NGU using 2 separate control groups.
  71. Pannekoek Y, Trum J, Bleker O, van der Veen F, Spanjaard L, Dankert J. Cytokine concentrations in seminal plasma from subfertile men are not indicative of the presence of Ureaplasma urealyticum or Mycoplasma hominis in the lower genital tract. J Med Microbiol. 2000;49:697-700 pubmed
    The inflammatory response to the presence of Ureaplasma urealyticum or Mycoplasma hominis in the lower genital tract of subfertile men without any signs or symptoms of infection was investigated by measuring the concentrations of ..
  72. Kong F, James G, Ma Z, Gordon S, Bin W, Gilbert G. Phylogenetic analysis of Ureaplasma urealyticum--support for the establishment of a new species, Ureaplasma parvum. Int J Syst Bacteriol. 1999;49 Pt 4:1879-89 pubmed publisher
    In this study, the phylogenetic relationships between the two biovars and 14 serovars of Ureaplasma urealyticum were studied using the sequences of four different genes or genetic regions, namely: 16S rRNA genes; 16S-23S rRNA gene spacer ..
  73. Ogasawara K, Goodwin T. Efficacy of azithromycin in reducing lower genital Ureaplasma urealyticum colonization in women at risk for preterm delivery. J Matern Fetal Med. 1999;8:12-6 pubmed
    The purpose of this study was to determine if azithromycin is effective in reducing lower genital colonization of Ureaplasma urealyticum in women with preterm labor or preterm premature rupture of membranes (PROM).
  74. Mirnejad R, Amirmozafari N, Kazemi B. Simultaneous and rapid differential diagnosis of Mycoplasma genitalium and Ureaplasma urealyticum based on a polymerase chain reaction-restriction fragment length polymorphism. Indian J Med Microbiol. 2011;29:33-6 pubmed publisher
    The aim of this investigation was to simultaneously detect and differentiate Mycoplasma genitalium and Ureaplasma urealyticum in female patients suffering from genital complications by polymerase chain reaction (PCR)-restriction fragment ..
  75. Ekiel A, Friedek D, Romanik M, Jóźwiak J, Martirosian G. Occurrence of Ureaplasma parvum and Ureaplasma urealyticum in women with cervical dysplasia in Katowice, Poland. J Korean Med Sci. 2009;24:1177-81 pubmed publisher
    ..aim of this study was to evaluate the occurrence of genital mycoplasmas, especially Ureaplasma parvum and Ureaplasma urealyticum, in women with atypical squamous cells of undetermined significance (ASCUS), low grade squamous ..
  76. Kenny G, Cartwright F. Susceptibilities of Mycoplasma hominis, M. pneumoniae, and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibili. Antimicrob Agents Chemother. 2001;45:2604-8 pubmed
    The susceptibilities of Mycoplasma hominis, Mycoplasma pneumoniae, and Ureaplasma urealyticum to eight new antimicrobial agents were determined by agar dilution. M. pneumoniae was susceptible to the new glycylcycline GAR-936 at 0...
  77. Yoder B, Coalson J, Winter V, Siler Khodr T, Duffy L, Cassell G. Effects of antenatal colonization with ureaplasma urealyticum on pulmonary disease in the immature baboon. Pediatr Res. 2003;54:797-807 pubmed
    ..We studied the effects of antenatal Ureaplasma urealyticum (Uu) infection in the 125-d immature baboon...
  78. Denks K, Spaeth E, Jõers K, Randoja R, Talpsep T, Ustav M, et al. Coinfection of Chlamydia trachomatis, Ureaplasma urealyticum and human papillomavirus among patients attending STD clinics in Estonia. Scand J Infect Dis. 2007;39:714-8 pubmed
    ..Estonian STD clinics were subjected to PCR assay for human papillomavirus (HPV), Chlamydia trachomatis and Ureaplasma urealyticum biovar 2. The overall prevalence of coinfection was 8%...
  79. Cao X, Wang Y, Hu X, Qing H, Wang H. Real-time TaqMan polymerase chain reaction assays for quantitative detection and differentiation of Ureaplasma urealyticum and Ureaplasma parvum. Diagn Microbiol Infect Dis. 2007;57:373-8 pubmed
    Evidence has been presented that the species currently known as Ureaplasma urealyticum should be separated into 2 species-Ureaplasma parvum (previously, U. urealyticum biovar 1) and U. urealyticum (previously, U. urealyticum biovar 2)...
  80. Kalinka J, Krajewski P, Sobala W, Wasiela M, Brzezińska Błaszczyk E. The association between maternal cervicovaginal proinflammatory cytokines concentrations during pregnancy and subsequent early-onset neonatal infection. J Perinat Med. 2006;34:371-7 pubmed
  81. Xiao L, Paralanov V, Glass J, Duffy L, Robertson J, Cassell G, et al. Extensive horizontal gene transfer in ureaplasmas from humans questions the utility of serotyping for diagnostic purposes. J Clin Microbiol. 2011;49:2818-26 pubmed publisher
    Ureaplasma parvum and Ureaplasma urealyticum are sexually transmitted, opportunistic pathogens of the human urogenital tract. There are 14 known serovars distributed between the two species...
  82. Gdoura R, Kchaou W, Ammar Keskes L, Chakroun N, Sellemi A, Znazen A, et al. Assessment of Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, and Mycoplasma genitalium in semen and first void urine specimens of asymptomatic male partners of infertile couples. J Androl. 2008;29:198-206 pubmed
    ..were examined by in-house PCR for the presence of DNA of Chlamydia trachomatis, genital ureaplasmas (Ureaplasma urealyticum and Ureaplasma parvum) and genital mycoplasmas (Mycoplasma hominis and Mycoplasma genitalium)...
  83. Volgmann T, Ohlinger R, Panzig B. Ureaplasma urealyticum-harmless commensal or underestimated enemy of human reproduction? A review. Arch Gynecol Obstet. 2005;273:133-9 pubmed
    ..This article reviews the role, diagnosis and treatment of Ureaplasma infections in human reproduction...