mycoplasma ovipneumoniae

Summary

Summary: A species of gram-negative bacteria originally isolated from the LUNGS; TRACHEA; and NASAL CAVITY of SHEEP. It causes chronic interstitial pneumonia (PNEUMONIA, MYCOPLASMA) in both SHEEP and GOATS.

Top Publications

  1. McAuliffe L, Hatchell F, Ayling R, King A, Nicholas R. Detection of Mycoplasma ovipneumoniae in Pasteurella-vaccinated sheep flocks with respiratory disease in England. Vet Rec. 2003;153:687-8 pubmed
  2. Lin Y, Miles R, Nicholas R, Kelly D, Wood A. Isolation and immunological detection of Mycoplasma ovipneumoniae in sheep with atypical pneumonia, and lack of a role for Mycoplasma arginini. Res Vet Sci. 2008;84:367-73 pubmed
    b>Mycoplasma ovipneumoniae NCTC 10151(T) and four new isolates from UK sheep flocks were compared...
  3. Weiser G, Drew M, Cassirer E, Ward A. Detection of Mycoplasma ovipneumoniae and M. arginini in bighorn sheep using enrichment culture coupled with genus- and species-specific polymerase chain reaction. J Wildl Dis. 2012;48:449-53 pubmed
    ..arginini and M. ovipneumoniae. Two methods of transport from field to laboratory (Port-a-Cul™ tubes, cryoprotectant in liquid N(2) and Fisher Transport System) gave similar results under our study conditions...
  4. Sheehan M, Cassidy J, Brady J, Ball H, Doherty M, Quinn P, et al. An aetiopathological study of chronic bronchopneumonia in lambs in Ireland. Vet J. 2007;173:630-7 pubmed
    ..Infection with both Mycoplasma ovipneumoniae and Mannheimia haemolytica have been implicated in the aetiology of this condition and a variety of ..
  5. Parham K, Churchward C, McAuliffe L, Nicholas R, Ayling R. A high level of strain variation within the Mycoplasma ovipneumoniae population of the UK has implications for disease diagnosis and management. Vet Microbiol. 2006;118:83-90 pubmed
    b>Mycoplasma ovipneumoniae is one of only two mycoplasma species associated with small ruminant disease in Britain and has been associated with an increasing number of disease outbreaks since 2002...
  6. Besser T, Highland M, Baker K, Cassirer E, Anderson N, Ramsey J, et al. Causes of pneumonia epizootics among bighorn sheep, Western United States, 2008-2010. Emerg Infect Dis. 2012;18:406-14 pubmed publisher
    ..respiratory pathogens Mannheimia haemolytica, Bibersteinia trehalosi, Pasteurella multocida, and Mycoplasma ovipneumoniae in lung tissue from 44 bighorn sheep from herds affected by 8 outbreaks in the western United States. M...
  7. Besser T, Cassirer E, Yamada C, Potter K, Herndon C, Foreyt W, et al. Survival of bighorn sheep (Ovis canadensis) commingled with domestic sheep (Ovis aries) in the absence of Mycoplasma ovipneumoniae. J Wildl Dis. 2012;48:168-72 pubmed
    To test the hypothesis that Mycoplasma ovipneumoniae is an important agent of the bighorn sheep (Ovis canadensis) pneumonia that has previously inevitably followed experimental commingling with domestic sheep (Ovis aries), we commingled M...
  8. Li M, Ma C, Liu X, Zhao D, Xu Q, Wang Y. Molecular cloning of HSP70 in Mycoplasma ovipneumoniae and comparison with that of other mycoplasmas. Genet Mol Res. 2011;10:834-48 pubmed publisher
    b>Mycoplasma ovipneumoniae, a bacterial species that specifically affects ovine and goat, is the cause of ovine infectious pleuropneumonia. We cloned, sequenced and analyzed heat shock protein 70 (HSP70) (dnaK) gene of M. ovipneumoniae...
  9. Yang F, Tang C, Wang Y, Zhang H, Yue H. Genome sequence of Mycoplasma ovipneumoniae strain SC01. J Bacteriol. 2011;193:5018 pubmed publisher
    b>Mycoplasma ovipneumoniae is associated with chronic nonprogressive pneumonia in both sheep and goats...

More Information

Publications40

  1. Besser T, Cassirer E, Potter K, VanderSchalie J, Fischer A, Knowles D, et al. Association of Mycoplasma ovipneumoniae infection with population-limiting respiratory disease in free-ranging Rocky Mountain bighorn sheep (Ovis canadensis canadensis). J Clin Microbiol. 2008;46:423-30 pubmed
    ..b>Mycoplasma ovipneumoniae was detected as a predominant member of the pneumonic lung flora in lambs with early lesions of ..
  2. Rudolph K, Hunter D, Rimler R, Cassirer E, Foreyt W, DeLong W, et al. Microorganisms associated with a pneumonic epizootic in Rocky Mountain bighorn sheep (Ovis canadensis canadensis). J Zoo Wildl Med. 2007;38:548-58 pubmed
    ..It was concluded that this epizootic resulted from a complex of factors including multiple potential respiratory pathogens, none of which were identified as a primary pathogen, and possible stress factors...
  3. Giangaspero M, Nicholas R, Hlusek M, Bonfini B, Osawa T, Orusa R, et al. Seroepidemiological survey of sheep flocks from Northern Japan for Mycoplasma ovipneumoniae and Mycoplasma agalactiae. Trop Anim Health Prod. 2012;44:395-8 pubmed publisher
    ..from Hokkaido, Iwate and Aomori, three northern prefectures of Japan, were screened for antibodies to Mycoplasma ovipneumoniae and Mycoplasma agalactiae by ELISA. Sixty four animals out of 246 (26%) were seropositive to M...
  4. Dassanayake R, Shanthalingam S, Herndon C, Subramaniam R, Lawrence P, Bavananthasivam J, et al. Mycoplasma ovipneumoniae can predispose bighorn sheep to fatal Mannheimia haemolytica pneumonia. Vet Microbiol. 2010;145:354-9 pubmed publisher
    b>Mycoplasma ovipneumoniae has been isolated from the lungs of pneumonic bighorn sheep (BHS). However experimental reproduction of fatal pneumonia in BHS with M. ovipneumoniae was not successful. Therefore the specific role, if any, of M...
  5. Shahzad W, Ajuwape A, Rosenbusch R. Global suppression of mitogen-activated ovine peripheral blood mononuclear cells by surface protein activity from Mycoplasma ovipneumoniae. Vet Immunol Immunopathol. 2010;136:116-21 pubmed publisher
    b>Mycoplasma ovipneumoniae is associated with chronic non-progressive pneumonia of sheep and goats...
  6. Fernandez S, Galapero J, Rey J, Pérez C, Ramos A, Rosales R, et al. Investigations into the seasonal presence of Mycoplasma species in fattening lambs. Vet J. 2016;212:80-2 pubmed publisher
    ..Isolates of Mycoplasma species were obtained (n=?117), including Mycoplasma ovipneumoniae (n?=?18) and Mycoplasma arginini (n?=?99). Two seasonal periods were identified...
  7. Cheng C, Jun Q, Qingling M, Zhengxiang H, Yu M, Xuepeng C, et al. Serological and molecular survey of sheep infected with Mycoplasma ovipneumoniae in Xinjiang, China. Trop Anim Health Prod. 2015;47:1641-7 pubmed publisher
    ..In order to investigate the epidemic status of Mycoplasma ovipneumoniae infection in sheep, indirect hemagglutination assay was used to analyze 1679 serum samples collected from ..
  8. Raghavan B, Erickson K, Kugadas A, Batra S, Call D, Davis M, et al. Role of carriers in the transmission of pneumonia in bighorn sheep (Ovis canadensis). Biol Open. 2016;5:745-55 pubmed publisher
    ..and lambs born to them acquired pneumonia-causing pathogens (leukotoxin-producing Pasteurellaceae and Mycoplasma ovipneumoniae), with subsequent lamb mortality between 4-9?weeks of age...
  9. Li Y, Jiang Z, Xue D, Deng G, Li M, Liu X, et al. Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway. BMC Microbiol. 2016;16:222 pubmed
    b>Mycoplasma ovipneumoniae (M. ovipneumoniae) is a species of Mycoplasma bacteria that specifically infects sheep and goat, causing ovine infectious pleuropneumonia. However, the mechanism underlying the pathogen-host interaction between M...
  10. Manlove K, Cassirer E, Plowright R, Cross P, Hudson P. Contact and contagion: Probability of transmission given contact varies with demographic state in bighorn sheep. J Anim Ecol. 2017;86:908-920 pubmed publisher
    ..test whether bighorn sheep demographic states vary systematically in infectiousness or susceptibility to Mycoplasma ovipneumoniae, an agent responsible for bighorn sheep pneumonia...
  11. Jiang F, He J, Navarro Alvarez N, Xu J, Li X, Li P, et al. Elongation Factor Tu and Heat Shock Protein 70 Are Membrane-Associated Proteins from Mycoplasma ovipneumoniae Capable of Inducing Strong Immune Response in Mice. PLoS ONE. 2016;11:e0161170 pubmed publisher
    ..b>Mycoplasma ovipneumoniae (M. ovipneumoniae) is the causative agent of interstitial pneumonia in sheep, goat and bighorn...
  12. Wood M, Fox K, Jennings Gaines J, Killion H, Amundson S, Miller M, et al. How Respiratory Pathogens Contribute to Lamb Mortality in a Poorly Performing Bighorn Sheep ( Ovis canadensis ) Herd. J Wildl Dis. 2017;53:126-130 pubmed publisher
    ..Pathology from an additional six lambs born in 2013 was also evaluated. Mycoplasma ovipneumoniae , leukotoxigenic Mannheimia spp...
  13. Jiang F, He J, Navarro Alvarez N, Xu J, Li X, Li P, et al. Correction: Elongation Factor Tu and Heat Shock Protein 70 Are Membrane-Associated Proteins from Mycoplasma ovipneumoniae Capable of Inducing Strong Immune Response in Mice. PLoS ONE. 2017;12:e0189562 pubmed publisher
    ..This corrects the article DOI: 10.1371/journal.pone.0161170.]...
  14. Grigg J, Wolfe L, Fox K, Killion H, Jennings Gaines J, Miller M, et al. Assessing Timing and Causes of Neonatal Lamb Losses in a Bighorn Sheep ( Ovis canadensis canadensis ) Herd via Use of Vaginal Implant Transmitters. J Wildl Dis. 2017;53:596-601 pubmed publisher
    ..Pneumonic lambs had involvement of Mycoplasma ovipneumoniae and leukotoxigenic Bibersteinia trehalosi ...
  15. Maksimovic Z, de la Fe C, Amores J, Gómez Martín A, Rifatbegović M. Comparison of phenotypic and genotypic profiles among caprine and ovine Mycoplasma ovipneumoniae strains. Vet Rec. 2017;180:180 pubmed publisher
    i>Mycoplasma ovipneumoniae (Movp) is considered to be one of the most important mycoplasmas causing respiratory disease in small ruminants...
  16. Plowright R, Manlove K, Besser T, Páez D, Andrews K, Matthews P, et al. Age-specific infectious period shapes dynamics of pneumonia in bighorn sheep. Ecol Lett. 2017;20:1325-1336 pubmed publisher
    ..We detected persistent infections of Mycoplasma ovipneumoniae, the primary causative agent of pneumonia in bighorn sheep (Ovis canadensis), in a small number of older ..
  17. Jiang Z, Song F, Li Y, Xue D, Deng G, Li M, et al. Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells. Mediators Inflamm. 2017;2017:9891673 pubmed publisher
    i>Mycoplasma ovipneumoniae (M. ovipneumoniae) is characterized as an etiological agent of primary atypical pneumonia that specifically infects sheep and goat...
  18. Raghavan B, Bavananthasivam J, Kugadas A, Haldorson G, Srikumaran S. Effect of vaccination against pneumonia on the survival of bighorn sheep (Ovis canadensis) commingled with carrier animals. Vet Microbiol. 2017;203:56-61 pubmed publisher
    ..Predisposing or concurrent infection with Mycoplasma ovipneumoniae enhances the severity of the disease, resulting in increased morbidity and mortality...
  19. Butler C, Edwards W, Jennings Gaines J, Killion H, Wood M, McWhirter D, et al. Assessing respiratory pathogen communities in bighorn sheep populations: Sampling realities, challenges, and improvements. PLoS ONE. 2017;12:e0180689 pubmed publisher
    ..The disease has been attributed to several bacterial pathogens including Mycoplasma ovipneumoniae and Pasteurellaceae pathogens belonging to the Mannheimia, Bibersteinia, and Pasteurella genera...
  20. Patel H, Mackintosh D, Ayling R, Nicholas R, Fielder M. A novel medium devoid of ruminant peptone for high yield growth of Mycoplasma ovipneumoniae. Vet Microbiol. 2008;127:309-14 pubmed
    b>Mycoplasma ovipneumoniae is considered an emerging veterinary pathogen causing pneumonia in sheep and goats worldwide. Currently it has not been possible to define a growth medium that yields the maximum growth of M...
  21. Catry B. Use of nasal swabs in diagnosis of respiratory disease. Vet Rec. 2006;158:455-6; author reply 456 pubmed
  22. Besser T, Cassirer E, Potter K, Foreyt W. Exposure of bighorn sheep to domestic goats colonized with Mycoplasma ovipneumoniae induces sub-lethal pneumonia. PLoS ONE. 2017;12:e0178707 pubmed publisher
    ..The disease is polymicrobial but is initiated by Mycoplasma ovipneumoniae, which is commonly carried by both domestic sheep (O. aries) and goats (Capra aegagrus hircus)...
  23. Kilic A, Kalender H, Eroksuz H, Muz A, Tasdemir B. Identification by culture, PCR, and immunohistochemistry of mycoplasmas and their molecular typing in sheep and lamb lungs with pneumonia in Eastern Turkey. Trop Anim Health Prod. 2013;45:1525-31 pubmed publisher
    ..The lung samples were examined by the immunoperoxidase method using hyperimmune Mycoplasma ovipneumoniae serum. The randomly amplified polymorphic DNA (RAPD) test was used for the molecular typing of M...
  24. Jiang Z, Song F, Li Y, Xue D, Zhao N, Zhang J, et al. Capsular Polysaccharide of Mycoplasma ovipneumoniae Induces Sheep Airway Epithelial Cell Apoptosis via ROS-Dependent JNK/P38 MAPK Pathways. Oxid Med Cell Longev. 2017;2017:6175841 pubmed publisher
    In an attempt to better understand the pathogen-host interaction between invading Mycoplasma ovipneumoniae (M...
  25. Ytrehus B, Davidson R, Isaksen K. Single Causative Factor for Severe Pneumonia Epizootics in Muskoxen?. Ecohealth. 2015;12:395-7 pubmed publisher
  26. Gonçalves R, Mariano I, Nunez A, Branco S, Fairfoul G, Nicholas R. Atypical non-progressive pneumonia in goats. Vet J. 2010;183:219-21 pubmed publisher
    An outbreak of severe respiratory disease in a goat herd was associated with Mycoplasma ovipneumoniae, Mycoplasma arginini, Mannheimia haemolytica and Pasteurella multocida with mortality rates exceeding 20% in kids...
  27. Xue D, Li Y, Jiang Z, Deng G, Li M, Liu X, et al. A ROS-dependent and Caspase-3-mediated apoptosis in sheep bronchial epithelial cells in response to Mycoplasma Ovipneumoniae infections. Vet Immunol Immunopathol. 2017;187:55-63 pubmed publisher
    b>Mycoplasma Ovipneumoniae (M. ovipneumoniae) is a primary etiological agent of enzootic pneumonia in sheep and goats...
  28. Zhang B, Han X, Yue H, Tang C. Molecular characterization of the heat shock protein 70 gene in Mycoplasma ovipneumoniae. Vet J. 2013;198:299-301 pubmed publisher
    b>Mycoplasma ovipneumoniae is a species of mycoplasma bacteria that commonly infects the respiratory tract, causing respiratory disease in sheep and goats worldwide...
  29. Besser T, Frances Cassirer E, Highland M, Wolff P, Justice Allen A, Mansfield K, et al. Bighorn sheep pneumonia: sorting out the cause of a polymicrobial disease. Prev Vet Med. 2013;108:85-93 pubmed publisher
    ..initial discovery, and at various times lungworms, Mannheimia haemolytica and other Pasteurellaceae, and Mycoplasma ovipneumoniae have been proposed as primary causal agents...
  30. Xu J, Chu Y, Gao P, Zhao P, He Y, Yan G, et al. [Molecular typing and immunoblotting of 17 Mycoplasma ovipneumoniae isolates from China]. Wei Sheng Wu Xue Bao. 2011;51:1421-6 pubmed
    To study the heterogeneity and immunogenic variability among Mycoplasma ovipneumoniae (M. ovipneumoniae) isolates from different regions of China.
  31. Sheehan M, Markey B, Cassidy J, Ball H, Duane M, Doherty M. New transtracheal bronchoalveolar lavage technique for the diagnosis of respiratory disease in sheep. Vet Rec. 2005;157:309-13 pubmed
    ..The detection of Mannheimia haemolytica and Mycoplasma ovipneumoniae or parainfluenza virus type 3 and bovine respiratory syncytial virus antigen in the lavage samples was ..