mycoplasma hominis

Summary

Summary: A common inhabitant of the vagina and cervix and a potential human pathogen, causing infections of the male and female reproductive tracts. It has also been associated with respiratory disease and pharyngitis. (From Dorland, 28th ed)

Top Publications

  1. Takahashi S, Takeyama K, Miyamoto S, Ichihara K, Maeda T, Kunishima Y, et al. Detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum DNAs in urine from asymptomatic healthy young Japanese men. J Infect Chemother. 2006;12:269-71 pubmed
    ..C. trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum in first-voided urine specimens were detected by polymerase ..
  2. Kilic D, Basar M, Kaygusuz S, Yilmaz E, Basar H, Batislam E. Prevalence and treatment of Chlamydia trachomatis, Ureaplasma urealyticum, and Mycoplasma hominis in patients with non-gonococcal urethritis. Jpn J Infect Dis. 2004;57:17-20 pubmed
    The aim of present study was to evaluate the occurrence of Chlamydia trachomatis, Mycoplasma hominis, and Ureaplasma urealyticum in non-gonococcal urethritis (NGU) and to determine the bacterial resistance to six antibiotics in order to ..
  3. Bebear C, de Barbeyrac B, Pereyre S, Renaudin H, Clerc M, Bebear C. Activity of moxifloxacin against the urogenital mycoplasmas Ureaplasma spp., Mycoplasma hominis and Mycoplasma genitalium and Chlamydia trachomatis. Clin Microbiol Infect. 2008;14:801-5 pubmed publisher
    ..54 strains of Mycoplasma hominis, 14 strains of Mycoplasma genitalium, and 44 strains of Chlamydia trachomatis...
  4. Gdoura R, Kchaou W, Ammar Keskes L, Chakroun N, Sellemi A, Znazen A, et al. Assessment of Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, and Mycoplasma genitalium in semen and first void urine specimens of asymptomatic male partners of infertile couples. J Androl. 2008;29:198-206 pubmed
    ..trachomatis, genital ureaplasmas (Ureaplasma urealyticum and Ureaplasma parvum) and genital mycoplasmas (Mycoplasma hominis and Mycoplasma genitalium)...
  5. Xiao J, Xie L, Fang S, Gao M, Zhu Y, Song L, et al. Symbiosis of Mycoplasma hominis in Trichomonas vaginalis may link metronidazole resistance in vitro. Parasitol Res. 2006;100:123-30 pubmed
    ..collected from patients in Guangzhou, China from 2003 to 2004 were found to be naturally infected with Mycoplasma hominis, as determined by PCR using specific primers...
  6. Henrich B, Lang K, Kitzerow A, MacKenzie C, Hadding U. Truncation as a novel form of variation of the p50 gene in Mycoplasma hominis. Microbiology. 1998;144 ( Pt 11):2979-85 pubmed
    ..The ubiquity of the gene encoding P50, an adhesin of Mycoplasma hominis FBG, and its transcription were analysed in different isolates of M. hominis...
  7. Hopfe M, Hoffmann R, Henrich B. P80, the HinT interacting membrane protein, is a secreted antigen of Mycoplasma hominis. BMC Microbiol. 2004;4:46 pubmed
    Mycoplasmas are cell wall-less bacteria which encode a minimal set of proteins. In Mycoplasma hominis, the genes encoding the surface-localized membrane complex P60/P80 are in an operon with a gene encoding a cytoplasmic, nucleotide-..
  8. Kupila L, Rantakokko Jalava K, Jalava J, Peltonen R, Marttila R, Kotilainen E, et al. Brain abscess caused by Mycoplasma hominis: a clinically recognizable entity?. Eur J Neurol. 2006;13:550-1 pubmed
  9. Karabay O, Topcuoglu A, Kocoglu E, Gurel S, Gurel H, Ince N. Prevalence and antibiotic susceptibility of genital Mycoplasma hominis and Ureaplasma urealyticum in a university hospital in Turkey. Clin Exp Obstet Gynecol. 2006;33:36-8 pubmed
    ..to assess the colonization prevalence and antibiotic susceptibility of genital Ureaplasma urealyticum and Mycoplasma hominis in a teaching hospital, in Turkey...

More Information

Publications91

  1. Hopfe M, Deenen R, Degrandi D, Köhrer K, Henrich B. Host cell responses to persistent mycoplasmas--different stages in infection of HeLa cells with Mycoplasma hominis. PLoS ONE. 2013;8:e54219 pubmed publisher
    b>Mycoplasma hominis is a facultative human pathogen primarily associated with bacterial vaginosis and pelvic inflammatory disease, but it is also able to spread to other sites, leading to arthritis or, in neonates, meningitis...
  2. Ladefoged S, Christiansen G. A GTP-binding protein of Mycoplasma hominis: a small sized homolog to the signal recognition particle receptor FtsY. Gene. 1997;201:37-44 pubmed
    ..recognition particle receptor (SRalpha) in the membrane of the endoplasmic reticulum, was identified in Mycoplasma hominis and its encoding DNA sequenced. The aa similarity to E. coli FtsY and B...
  3. Salmeri M, Valenti D, La Vignera S, Bellanca S, Morello A, Toscano M, et al. Prevalence of Ureaplasma urealyticum and Mycoplasma hominis infection in unselected infertile men. J Chemother. 2012;24:81-6 pubmed publisher
    In this study, we investigated the prevalence of Ureaplasma urealyticum and Mycoplasma hominis infection among 250 unselected infertile men, the presence of urogenital symptoms in infected men and the effects of these microorganisms on ..
  4. Lee J, Kim K, Lee H, Yang K, Seo J, Choe J. Concordance of Ureaplasma urealyticum and Mycoplasma hominis in infertile couples: impact on semen parameters. Urology. 2013;81:1219-24 pubmed publisher
    ..between mycoplasma infection and human infertility, we determined the concordance of Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) detection in infertile and fertile couples, and assessed semen parameters in both groups.
  5. Hopfe M, Henrich B. OppA, the ecto-ATPase of Mycoplasma hominis induces ATP release and cell death in HeLa cells. BMC Microbiol. 2008;8:55 pubmed publisher
    In the facultative human pathogen Mycoplasma hominis, which belongs to the cell wall-less Mollicutes, the surface-localised substrate-binding domain OppA of the oligopeptide permease was characterised as the main ecto-ATPase...
  6. Petrikkos G, Hadjisoteriou M, Daikos G. PCR versus culture in the detection of vaginal Ureaplasma urealyticum and Mycoplasma hominis. Int J Gynaecol Obstet. 2007;97:202-3 pubmed
  7. Escamilla F, Fernandez M, Espigares A, Arnal C, Ortega A, Garcia T. [Subdural empyema due to Mycoplasma hominis following epidural anesthesia]. Rev Neurol. 2000;30:326-8 pubmed
    ..In the literature there are sporadic reports of spinal epidural abscesses after epidural anaesthesia (Staphylococcus aureus in 82%), whilst subdural empyemas are more often related to ear and sinus conditions...
  8. Baka S, Kouskouni E, Antonopoulou S, Sioutis D, Papakonstantinou M, Hassiakos D, et al. Prevalence of Ureaplasma urealyticum and Mycoplasma hominis in women with chronic urinary symptoms. Urology. 2009;74:62-6 pubmed publisher
    To assess the prevalence of Ureaplasma urealyticum and Mycoplasma hominis in women experiencing chronic urinary symptoms.
  9. Lanzafame M, Delama A, Lattuada E, Faggian F, Padovani G, Concia E, et al. Prevalence and clinical significance of Ureaplasma urealyticum and Mycoplasma hominis in the lower genital tract of HIV-1-infected women. Infez Med. 2006;14:213-5 pubmed
    b>Mycoplasma hominis and Ureaplasma urealyticum are frequently isolated from the cervical and vaginal tracts of HIV-negative asymptomatic women...
  10. Kitzerow A, Henrich B. The cytosolic HinT protein of Mycoplasma hominis interacts with two membrane proteins. Mol Microbiol. 2001;41:279-87 pubmed
    ..In this study, we provide evidence that, in the cell wall-less prokaryote, Mycoplasma hominis, the gene encoding the HinT protein forms an operon with two other genes...
  11. Taylor Robinson D, Jensen J, Svenstrup H, Stacey C. Difficulties experienced in defining the microbial cause of pelvic inflammatory disease. Int J STD AIDS. 2012;23:18-24 pubmed publisher
    ..In all laparoscopic categories, Ureaplasma spp. and Mycoplasma hominis, but not Mycoplasma genitalium, were at least as common in the cervix/vagina as Chlamydia trachomatis and ..
  12. Waites K, Canupp K, Kenny G. In vitro susceptibilities of Mycoplasma hominis to six fluoroquinolones as determined by E test. Antimicrob Agents Chemother. 1999;43:2571-3 pubmed
    Twenty isolates of Mycoplasma hominis were tested for their susceptibility to six fluoroquinolones by the E test. The MICs at which 90% of the isolates were inhibited (in micrograms per milliliter) were as follows: sparfloxacin, 0...
  13. Mardassi B, Aissani N, Moalla I, Dhahri D, Dridi A, Mlik B. Evidence for the predominance of a single tet(M) gene sequence type in tetracycline-resistant Ureaplasma parvum and Mycoplasma hominis isolates from Tunisian patients. J Med Microbiol. 2012;61:1254-61 pubmed publisher
    ..Twenty Ureaplasma parvum, two Ureaplasma urealyticum and 48 Mycoplasma hominis isolates, recovered from Tunisian patients with urogenital and infertility disorders, were evaluated for ..
  14. Vancini R, Benchimol M. Entry and intracellular location of Mycoplasma hominis in Trichomonas vaginalis. Arch Microbiol. 2008;189:7-18 pubmed
    ..vaginalis in association with Mycoplasma fermentans or Mycoplasma hominis. However, the consequences and behavior of mycoplasma during trichomonad infections are virtually unknown...
  15. Myers P, Khabiri E, Greub G, Kalangos A. Mycoplasma hominis mediastinitis after acute aortic dissection repair. Interact Cardiovasc Thorac Surg. 2010;11:857-8 pubmed publisher
    We report a case of ascending aortic graft infection by an atypical bacteria, Mycoplasma hominis, with mediastinitis, a dreaded complication after cardiac surgery...
  16. Marini H, Merle V, Frebourg N, Godier S, Bastit D, Benadiba L, et al. Mycoplasma hominis wound infection after a vascular allograft. J Infect. 2008;57:272-4 pubmed publisher
    Cases of Mycoplasma hominis infections after allograft are rare. We report a case of M. hominis wound infection after a vascular allograft...
  17. Hopfe M, Dahlmanns T, Henrich B. In Mycoplasma hominis the OppA-mediated cytoadhesion depends on its ATPase activity. BMC Microbiol. 2011;11:185 pubmed publisher
    In Mycoplasma hominis, a facultative human pathogen of the human genital tract, OppA, the substrate-binding domain of the oligopeptide permease, is a multifunctional protein involved in nutrition uptake, cytoadhesion and hydrolysis of ..
  18. Clausen H, Fedder J, Drasbek M, Nielsen P, Toft B, Ingerslev H, et al. Serological investigation of Mycoplasma genitalium in infertile women. Hum Reprod. 2001;16:1866-74 pubmed
    ..trachomatis. This study indicates that M. genitalium may be an independent risk factor in the development of an inflammatory process leading to scarring of the uterine tubes in women and thereby causing infertility. ..
  19. Waites K, Duffy L, Bébéar C, Matlow A, Talkington D, Kenny G, et al. Standardized methods and quality control limits for agar and broth microdilution susceptibility testing of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum. J Clin Microbiol. 2012;50:3542-7 pubmed publisher
    ..for the performance and quality control of antimicrobial susceptibility testing of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum using broth microdilution and agar dilution techniques...
  20. Sato H, Iino N, Ohashi R, Saeki T, Ito T, Saito M, et al. Hypogammaglobulinemic patient with polyarthritis mimicking rheumatoid arthritis finally diagnosed as septic arthritis caused by Mycoplasma hominis. Intern Med. 2012;51:425-9 pubmed
    ..Finally, a diagnosis of disseminated Mycoplasma hominis infection was made...
  21. Sha B, Zariffard M, Wang Q, Chen H, Bremer J, Cohen M, et al. Female genital-tract HIV load correlates inversely with Lactobacillus species but positively with bacterial vaginosis and Mycoplasma hominis. J Infect Dis. 2005;191:25-32 pubmed
    ..HIV RNA, lactobacilli, Gardnerella vaginalis, and Mycoplasma hominis in cervicovaginal lavage (CVL) samples were quantified by polymerase chain reaction (PCR)...
  22. Søgaard I, Boesen T, Mygind T, Melkova R, Birkelund S, Christiansen G, et al. Recombination in Mycoplasma hominis. Infect Genet Evol. 2002;1:277-85 pubmed
    b>Mycoplasma hominis has been previously described as a heterogeneous species, and in the present study intraspecies diversity of 20 M...
  23. Andrade Rocha F. Ureaplasma urealyticum and Mycoplasma hominis in men attending for routine semen analysis. Prevalence, incidence by age and clinical settings, influence on sperm characteristics, relationship with the leukocyte count and clinical value. Urol Int. 2003;71:377-81 pubmed
    To investigate the clinical value of the screening of Ureaplasma urealyticum and Mycoplasma hominis in routine semen analysis.
  24. Waites K, Crabb D, Duffy L. Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas. Antimicrob Agents Chemother. 2008;52:3776-8 pubmed publisher
    The in vitro susceptibilities of 151 unique clinical isolates of Mycoplasma pneumoniae, Mycoplasma hominis, Mycoplasma fermentans, Mycoplasma genitalium, and Ureaplasma species to DC-159a, an investigational fluoroquinolone, in comparison ..
  25. Butler S, Augostini P, Secor W. Mycoplasma hominis infection of Trichomonas vaginalis is not associated with metronidazole-resistant trichomoniasis in clinical isolates from the United States. Parasitol Res. 2010;107:1023-7 pubmed publisher
    ..In a recent study, Chinese T. vaginalis isolates that were polymerase chain reaction (PCR) positive for Mycoplasma hominis DNA demonstrated greater in vitro resistance to metronidazole than isolates with no evidence of M...
  26. Rodrigues M, Fernandes P, Haddad J, Paiva M, Souza M, Andrade T, et al. Frequency of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Mycoplasma hominis and Ureaplasma species in cervical samples. J Obstet Gynaecol. 2011;31:237-41 pubmed publisher
    ..the relative frequencies of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Mycoplasma hominis and Ureaplasma sp. in cervical samples...
  27. Raherison S, Gonzalez P, Renaudin H, Charron A, Bebear C, Bebear C. Evidence of active efflux in resistance to ciprofloxacin and to ethidium bromide by Mycoplasma hominis. Antimicrob Agents Chemother. 2002;46:672-9 pubmed
    The uptake of fluoroquinolones was characterized for the fluoroquinolone-susceptible strain PG21 of Mycoplasma hominis. Accumulation of fluoroquinolones appeared to occur by passive diffusion...
  28. Hellberg D, Nilsson S, Mardh P. The diagnosis of bacterial vaginosis and vaginal flora changes. Arch Gynecol Obstet. 2001;265:11-5 pubmed
    ..which is easily performed, strongly suggests BV and a vaginal flora predominated by Gardnerella vaginalis, Mycoplasma hominis, Mobiluncus species and anaerobic species on one hand, and lack of lactobacilli on the other...
  29. Waites K, Schelonka R, Xiao L, Grigsby P, Novy M. Congenital and opportunistic infections: Ureaplasma species and Mycoplasma hominis. Semin Fetal Neonatal Med. 2009;14:190-9 pubmed publisher
    ..The ability of Ureaplasma spp. and Mycoplasma hominis to cause pneumonia, bacteremia, and meningitis in newborns can no longer be questioned...
  30. Bebear C, Renaudin H, Charron A, Gruson D, Lefrancois M, Bebear C. In vitro activity of trovafloxacin compared to those of five antimicrobials against mycoplasmas including Mycoplasma hominis and Ureaplasma urealyticum fluoroquinolone-resistant isolates that have been genetically characterized. Antimicrob Agents Chemother. 2000;44:2557-60 pubmed
    ..25 microg/ml. Whatever the associated mutations, trovafloxacin exhibited greater activity than the other fluoroquinolones tested against fluoroquinolone-resistant Mycoplasma hominis and U. urealyticum isolates.
  31. Yoshida T, Maeda S, Deguchi T, Miyazawa T, Ishiko H. Rapid detection of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum organisms in genitourinary samples by PCR-microtiter plate hybridization assay. J Clin Microbiol. 2003;41:1850-5 pubmed
    We present a method for detecting the presence of Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum organisms, which are thought to be associated with nongonococcal urethritis (NGU) and other ..
  32. Barykova Y, Logunov D, Shmarov M, Vinarov A, Fiev D, Vinarova N, et al. Association of Mycoplasma hominis infection with prostate cancer. Oncotarget. 2011;2:289-97 pubmed
    ..hominis infection may be involved in PCa development and may, therefore, be a potential PCa marker and/or target for improved prevention and treatment of this disease...
  33. Lee S, Romero R, Kim E, Yoon B. A high Nugent score but not a positive culture for genital mycoplasmas is a risk factor for spontaneous preterm birth. J Matern Fetal Neonatal Med. 2009;22:212-7 pubmed publisher
    ..This study was performed to evaluate the relationship among the Nugent score for the diagnosis of bacterial vaginosis (BV), the results of vaginal fluid culture for genital mycoplasmas, and the subsequent occurrence of preterm birth...
  34. Degrange S, Renaudin H, Charron A, Bebear C, Bebear C. Tetracycline resistance in Ureaplasma spp. and Mycoplasma hominis: prevalence in Bordeaux, France, from 1999 to 2002 and description of two tet(M)-positive isolates of M. hominis susceptible to tetracyclines. Antimicrob Agents Chemother. 2008;52:742-4 pubmed
    Twenty-four of 128 clinical isolates of Mycoplasma hominis and 6 of 276 clinical isolates of Ureaplasma spp. from Bordeaux, France (1999 to 2002), were resistant to tetracycline and harbored the tet(M) gene. For M...
  35. Bebear C, Renaudin H, Charron A, Clerc M, Pereyre S, Bebear C. DNA gyrase and topoisomerase IV mutations in clinical isolates of Ureaplasma spp. and Mycoplasma hominis resistant to fluoroquinolones. Antimicrob Agents Chemother. 2003;47:3323-5 pubmed
    Twelve clinical isolates of Ureaplasma spp. and one isolate of Mycoplasma hominis were examined for resistance to fluoroquinolones...
  36. Yamaguchi M, Kikuchi A, Ohkusu K, Akashi M, Sasahara J, Takakuwa K, et al. Abscess formation due to Mycoplasma hominis infection after cesarean section. J Obstet Gynaecol Res. 2009;35:593-6 pubmed publisher
    ..Consequently, she underwent transvaginal abscess drainage, after which she promptly became afebrile. Mycoplasma hominis was considered to be the primary causative organism...
  37. Samra Z, Rosenberg S, Soffer Y. In vitro susceptibility of Mycoplasma hominis clinical isolates to tetracyclines, quinolones and macrolides. Diagn Microbiol Infect Dis. 2002;44:359-61 pubmed
    ..tetracycline, erythromycin, roxithromycin, clarithromycin and azithromycin against 110 clinical isolates of Mycoplasma hominis. The minimal inhibitory concentrations (MICs) were determined with the Etest...
  38. Hidalgo Tenorio C, Pasquau J, Lopez Checa S, Lopez Ruz M. [Endocarditis due to Mycoplasma hominis]. Enferm Infecc Microbiol Clin. 2006;24:470-1 pubmed
  39. Rao R, Ghanayem N, Kaufman B, Kehl K, Gregg D, Chusid M. Mycoplasma hominis and Ureaplasma species brain abscess in a neonate. Pediatr Infect Dis J. 2002;21:1083-5 pubmed
  40. Gdoura R, Kchaou W, Chaari C, Znazen A, Keskes L, Rebai T, et al. Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis and Mycoplasma genitalium infections and semen quality of infertile men. BMC Infect Dis. 2007;7:129 pubmed
    Genital ureaplasmas (Ureaplasma urealyticum and Ureaplasma parvum) and mycoplasmas (Mycoplasma genitalium and Mycoplasma hominis) are potentially pathogenic species playing an etiologic role in both genital infections and male infertility...
  41. Sha B, Chen H, Wang Q, Zariffard M, Cohen M, Spear G. Utility of Amsel criteria, Nugent score, and quantitative PCR for Gardnerella vaginalis, Mycoplasma hominis, and Lactobacillus spp. for diagnosis of bacterial vaginosis in human immunodeficiency virus-infected women. J Clin Microbiol. 2005;43:4607-12 pubmed
    ..Lactobacilli, Gardnerella vaginalis, and Mycoplasma hominis in cervicovaginal lavage samples were quantified by PCR...
  42. Daxboeck F, Zitta S, Stadler M, Iro E, Krause R. Mycoplasma hominis and Ureaplasma urealyticum in patients with sterile pyuria. J Infect. 2005;51:54-8 pubmed
    b>Mycoplasma hominis and Ureaplasma urealyticum are associated with various diseases of the urogenital tract, but they are usually not detected by routine microbiological diagnosis...
  43. Wolthers K, Kornelisse R, Platenkamp G, Schuurman van der Lem M, van der Schee C, Hartwig N, et al. A case of Mycoplasma hominis meningo-encephalitis in a full-term infant: rapid recovery after start of treatment with ciprofloxacin. Eur J Pediatr. 2003;162:514-516 pubmed publisher
    ..v.), to which M. hominisis susceptible...
  44. Perni S, Vardhana S, Korneeva I, Tuttle S, Paraskevas L, Chasen S, et al. Mycoplasma hominis and Ureaplasma urealyticum in midtrimester amniotic fluid: association with amniotic fluid cytokine levels and pregnancy outcome. Am J Obstet Gynecol. 2004;191:1382-6 pubmed
    The association between the detection of Mycoplasma hominis or Ureaplasma urealyticum in midtrimester amniotic fluid and amniotic fluid cytokine concentrations and subsequent pregnancy outcome were examined.
  45. Goldenberg R, Andrews W, Goepfert A, Faye Petersen O, Cliver S, Carlo W, et al. The Alabama Preterm Birth Study: umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infants. Am J Obstet Gynecol. 2008;198:43.e1-5 pubmed publisher
    ..was undertaken to evaluate the frequency of umbilical cord blood infections with Ureaplasma urealyticum and Mycoplasma hominis in preterm 23- to 32-week births and to determine their association with various obstetric conditions, ..
  46. Capoccia R, Greub G, Baud D. Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes. Curr Opin Infect Dis. 2013;26:231-40 pubmed publisher
    b>Mycoplasma hominis and Ureaplasma urealyticum may colonize the human genital tract and have been associated with adverse pregnancy outcomes...
  47. García C, Ugalde E, Monteagudo I, Saez A, Aguero J, Martinez Martinez L, et al. Isolation of Mycoplasma hominis in critically ill patients with pulmonary infections: clinical and microbiological analysis in an intensive care unit. Intensive Care Med. 2007;33:143-7 pubmed
    b>Mycoplasma hominis is a well recognized extragenital pathogen. However, it is an uncommon cause of respiratory infections in critically ill patients admitted to the intensive care unit (ICU).
  48. Díaz García F, Herrera Mendoza A, Giono Cerezo S, Guerra Infante F. Mycoplasma hominis attaches to and locates intracellularly in human spermatozoa. Hum Reprod. 2006;21:1591-8 pubmed
    ..The study of sperm-mycoplasma interaction has been focused on the effects of infection on sperm quality, but few studies have reported the direct interaction of this bacterium with spermatozoa...
  49. Hata A, Honda Y, Asada K, Sasaki Y, Kenri T, Hata D. Mycoplasma hominis meningitis in a neonate: case report and review. J Infect. 2008;57:338-43 pubmed publisher
    Despite frequent colonization with Mycoplasma hominis, the invasive disease is rare in neonates. This study describes a neonatal case with meningitis in which M...
  50. Blasco M, Torres L, Marco M, Moles B, Villuendas M, García Moya J. Prosthetic valve endocarditis caused by Mycoplasma hominis. Eur J Clin Microbiol Infect Dis. 2000;19:638-40 pubmed
    b>Mycoplasma hominis endocarditis is extremely uncommon and difficult to diagnose...
  51. Dessi D, Rappelli P, Diaz N, Cappuccinelli P, Fiori P. Mycoplasma hominis and Trichomonas vaginalis: a unique case of symbiotic relationship between two obligate human parasites. Front Biosci. 2006;11:2028-34 pubmed
    ..b>Mycoplasma hominis is a human sexually transmitted mycoplasma which is able to establish a biological association with ..
  52. Zhu C, Liu J, Ling Y, Dong C, Wu T, Yu X, et al. Prevalence and antimicrobial susceptibility of Ureaplasma urealyticum and Mycoplasma hominis in Chinese women with genital infectious diseases. Indian J Dermatol Venereol Leprol. 2012;78:406-7 pubmed publisher
    Previous studies have confirmed that the presence of Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) increases the risks of various diseases including genital infections in women...
  53. Mardassi B, Ayari H, Béjaoui Khiari A, Mlik B, Moalla I, Amouna F. Genetic variability of the P120' surface protein gene of Mycoplasma hominis isolates recovered from Tunisian patients with uro-genital and infertility disorders. BMC Infect Dis. 2007;7:142 pubmed
    Among the surface antigens of Mycoplasma hominis, the P120' protein was previously shown to elicit a subtle antibody response and appears to be relatively conserved...
  54. Rosemond A, Lanotte P, Watt S, Sauget A, Guerif F, Royere D, et al. [Systematic screening tests for Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum in urogenital specimens of infertile couples]. Pathol Biol (Paris). 2006;54:125-9 pubmed
    ..Tours, with the scope to determine if there is a benefit for systematic screening of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum among genito-urinary specimen when exploring couples infertility. C...
  55. McCarthy K, Looke D. Successful treatment of post-neurosurgical intracranial Mycoplasma hominis infection using gatifloxacin. J Infect. 2008;57:344-6 pubmed publisher
    We describe two cases of intracerebral infection with Mycoplasma hominis following neurosurgery, the first after removal of a colloid cyst, the other after a craniotomy following a motor vehicle accident (MVA)...
  56. Rohner P, Schnyder I, Ninet B, Schrenzel J, Lew D, Ramla T, et al. Severe Mycoplasma hominis infections in two renal transplant patients. Eur J Clin Microbiol Infect Dis. 2004;23:203-4 pubmed
    Systemic infections due to Mycoplasma hominis are rare and occur mainly in immunocompromised patients. Reported here are the cases of two renal transplant patients with peritonitis who did not respond to empirical antimicrobial treatment...
  57. Lazarev V, Parfenova T, Gularyan S, Misyurina O, Akopian T, Govorun V. Induced expression of melittin, an antimicrobial peptide, inhibits infection by Chlamydia trachomatis and Mycoplasma hominis in a HeLa cell line. Int J Antimicrob Agents. 2002;19:133-7 pubmed
    ..within recombinant plasmid vectors, on infection with urogenital pathogens Chlamydia trachomatis and Mycoplasma hominis in HeLa cell culture...
  58. Boesen T, Fedosova N, Kjeldgaard M, Birkelund S, Christiansen G. Molecular design of Mycoplasma hominis Vaa adhesin. Protein Sci. 2001;10:2577-86 pubmed
    The variable adherence-associated (Vaa) adhesin of the opportunistic human pathogen Mycoplasma hominis is a surface-exposed, membrane-associated protein involved in the attachment of the bacterium to host cells...
  59. Soroka A, Momynaliev K, Taraskina A, Savicheva A, Govorun V. Genetic heterogeneity of Mycoplasma hominis clinical isolates detected during observation of patients with recurrent urogenital inflammation. Bull Exp Biol Med. 2001;132:663-5 pubmed
    A rapid reproducible effective method for molecular typing of Mycoplasma hominis strains based on random amplified polymorphic DNA (RAPD) technique was developed...
  60. Zhang Q, Wise K. Coupled phase-variable expression and epitope masking of selective surface lipoproteins increase surface phenotypic diversity in Mycoplasma hominis. Infect Immun. 2001;69:5177-81 pubmed
    ..Exposure of surface epitopes on a constitutively expressed membrane protein (P56) of Mycoplasma hominis was subject to high-frequency phase variation due to phase-variable expression of the P120 antigen and its ..
  61. Takeyama K, Mitsuzawa H, Shimizu T, Konishi M, Nishitani C, Sano H, et al. Prostate cell lines secrete IL-8 in response to Mycoplasma hominis through Toll-like receptor 2-mediated mechanism. Prostate. 2006;66:386-91 pubmed
    ..The roles of Toll-like receptor 2 (TLR2) and Mycoplasma in prostate inflammation remain unclear. We investigated whether Mycoplasma induced inflammatory cytokine secretion through TLR2-mediated mechanism in prostate cancer cell line...
  62. Casari E, Ferrario A, Morenghi E, Montanelli A. Gardnerella, Trichomonas vaginalis, Candida, Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum in the genital discharge of symptomatic fertile and asymptomatic infertile women. New Microbiol. 2010;33:69-76 pubmed
    ..and the presence of Gardnerella vaginalis, Trichomonas vaginalis, Candida species, Streptococcus agalactiae, Mycoplasma hominis, Ureaplasma urealyiticum and Chlamydia trachomatis were retrospectively analyzed...
  63. Boesen T, Emmersen J, Baczynska A, Birkelund S, Christiansen G. The vaa locus of Mycoplasma hominis contains a divergent genetic islet encoding a putative membrane protein. BMC Microbiol. 2004;4:37 pubmed
    The Mycoplasma hominis vaa gene encodes a highly variable, surface antigen involved in the adhesion to host cells. We have analysed the structure of the vaa locus to elucidate the genetic basis for variation of vaa.
  64. Ngan C, Lim T, Choo C, Toh G, Lim Y. Susceptibility testing of Singapore strains of Mycoplasma hominis to tetracycline, gatifloxacin, moxifloxacin, ciprofloxacin, clindamycin, and azithromycin by the Etest method. Diagn Microbiol Infect Dis. 2004;48:207-10 pubmed
    ..gatifloxacin, moxifloxacin, ciprofloxacin, clindamycin and azithromycin for 28 Singapore clinical Mycoplasma hominis strains were studied using the Etest method...
  65. Pereyre S, Gonzalez P, de Barbeyrac B, Darnige A, Renaudin H, Charron A, et al. Mutations in 23S rRNA account for intrinsic resistance to macrolides in Mycoplasma hominis and Mycoplasma fermentans and for acquired resistance to macrolides in M. hominis. Antimicrob Agents Chemother. 2002;46:3142-50 pubmed
    The mechanisms of intrinsic resistance of Mycoplasma hominis to 14- and 15-membered macrolides were investigated in comparison with those of M. pneumoniae, which is naturally susceptible to macrolides...
  66. Zdrodowska Stefanow B, Kłosowska W, Ostaszewska Puchalska I, Bułhak Kozioł V, Kotowicz B. Ureaplasma urealyticum and Mycoplasma hominis infection in women with urogenital diseases. Adv Med Sci. 2006;51:250-3 pubmed
    The aim of the study was to assess the incidence of Ureaplasma urealyticum (U. urealyticum) and Mycoplasma hominis (M. hominis) infection in women with urogenital diseases.
  67. Abdel Haq N, Asmar B, Brown W. Mycoplasma hominis scalp abscess in the newborn. Pediatr Infect Dis J. 2002;21:1171-3 pubmed
    ..We present a newborn with no apparent scalp trauma who developed scalp abscess that yielded pure growth of Mycoplasma hominis. The clue to diagnosis was the growth of pinpoint translucent colonies on blood agar that were Gram stain-..
  68. Egawa T, Morioka I, Morisawa T, Yokoyama N, Nakao H, Ohashi M, et al. Ureaplasma urealyticum and Mycoplasma hominis presence in umbilical cord is associated with pathogenesis of funisitis. Kobe J Med Sci. 2007;53:241-9 pubmed
    Ureaplasma urealyticum (U. urealyticum) and Mycoplasma hominis (M...
  69. House P, Dunn J, Carroll K, MacDonald J. Seeding of a cavernous angioma with Mycoplasma hominis: case report. Neurosurgery. 2003;53:749-52; discussion 752-3 pubmed
    To describe a unique case of hematogenous seeding of a cavernous angioma with the commensal organism Mycoplasma hominis.
  70. Arya O, Tong C, Hart C, Pratt B, Hughes S, Roberts P, et al. Is Mycoplasma hominis a vaginal pathogen?. Sex Transm Infect. 2001;77:58-62 pubmed
    To evaluate the role of Mycoplasma hominis as a vaginal pathogen.
  71. Baczynska A, Funch P, Fedder J, Knudsen H, Birkelund S, Christiansen G. Morphology of human Fallopian tubes after infection with Mycoplasma genitalium and Mycoplasma hominis--in vitro organ culture study. Hum Reprod. 2007;22:968-79 pubmed
    ..We analysed the effects of infections with Mycoplasma hominis and Mycoplasma genitalium on the HFT epithelium and compared them with the effects of infections with ..
  72. Pettersson B, Tully J, Bölske G, Johansson K. Updated phylogenetic description of the Mycoplasma hominis cluster (Weisburg et al. 1989) based on 16S rDNA sequences. Int J Syst Evol Microbiol. 2000;50 Pt 1:291-301 pubmed
    ..In this report we have determined the phylogeny of the Mycoplasma hominis cluster of the hominis group...
  73. Dessi D, Delogu G, Emonte E, Catania M, Fiori P, Rappelli P. Long-term survival and intracellular replication of Mycoplasma hominis in Trichomonas vaginalis cells: potential role of the protozoon in transmitting bacterial infection. Infect Immun. 2005;73:1180-6 pubmed
    The existence of a symbiotic relationship between Trichomonas vaginalis and Mycoplasma hominis, which is the first reported example of symbiosis between two obligate human pathogens, has been recently reported by our research group...
  74. Dominguez S, Littlehorn C, Nyquist A. Mycoplasma hominis endocarditis in a child with a complex congenital heart defect. Pediatr Infect Dis J. 2006;25:851-2 pubmed
    ..This is the first reported case of Mycoplasma endocarditis in a child and suggests consideration of this organism as a cause of culture-negative endocarditis...
  75. Ladefoged S, Christiansen G. Mycoplasma hominis expresses two variants of a cell-surface protein, one a lipoprotein, and one not. Microbiology. 1998;144 ( Pt 3):761-70 pubmed
    ..characterized variable surface-exposed membrane protein P120 was identified (P120'), establishing that Mycoplasma hominis PG21 possesses a novel gene family...
  76. Hopfe M, Henrich B. OppA, the substrate-binding subunit of the oligopeptide permease, is the major Ecto-ATPase of Mycoplasma hominis. J Bacteriol. 2004;186:1021-928 pubmed
    ..However, external membrane-bound ATPases have also been described in parasites and eukaryotic cells. In Mycoplasma hominis, a bacterium lacking a cell wall, the surface-exposed substrate-binding protein OppA of an oligopeptide ..
  77. Baczynska A, Svenstrup H, Fedder J, Birkelund S, Christiansen G. Development of real-time PCR for detection of Mycoplasma hominis. BMC Microbiol. 2004;4:35 pubmed
    b>Mycoplasma hominis is associated with pelvic inflammatory disease, bacterial vaginosis, post partum fever, sepsis and infections of the central nervous system often leading to serious conditions...
  78. Lazarev V, Shkarupeta M, Titova G, Kostrjukova E, Akopian T, Govorun V. Effect of induced expression of an antimicrobial peptide melittin on Chlamydia trachomatis and Mycoplasma hominis infections in vivo. Biochem Biophys Res Commun. 2005;338:946-50 pubmed
    ..gene transcription with doxycycline markedly suppressed subsequent genital tract infection of mice by Mycoplasma hominis and Chlamydia trachomatis...
  79. Maeda S, Tamaki M, Kubota Y, Nguyen P, Yasuda M, Deguchi T. Treatment of men with urethritis negative for Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum. Int J Urol. 2007;14:422-5 pubmed
    ..trachomatis-positive NGU have been performed. We assessed the efficacy of antimicrobial agents that are active against C. trachomatis on non-mycoplasmal, non-ureaplasmal and non-chlamydial NGU (NMNUNCNGU)...
  80. Romero R, Schaudinn C, Kusanovic J, Gorur A, Gotsch F, Webster P, et al. Detection of a microbial biofilm in intraamniotic infection. Am J Obstet Gynecol. 2008;198:135.e1-5 pubmed publisher
    ..A case is presented in which "amniotic fluid sludge" was found to contain microbial biofilms. This represents the first report of a microbial biofilm in the amniotic cavity...
  81. Baczynska A, Hvid M, Lamy P, Birkelund S, Christiansen G, Fedder J. Prevalence of Mycoplasma genitalium, Mycoplasma hominis and Chlamydia trachomatis among Danish patients requesting abortion. Syst Biol Reprod Med. 2008;54:127-34 pubmed publisher
    ..genitalium) and to compare it to the carriage rates of Mycoplasma hominis (M. hominis ) and Chlamydia trachomatis (C...
  82. Pereyre S, Sirand Pugnet P, Beven L, Charron A, Renaudin H, Barré A, et al. Life on arginine for Mycoplasma hominis: clues from its minimal genome and comparison with other human urogenital mycoplasmas. PLoS Genet. 2009;5:e1000677 pubmed publisher
    b>Mycoplasma hominis is an opportunistic human mycoplasma. Two other pathogenic human species, M. genitalium and Ureaplasma parvum, reside within the same natural niche as M. hominis: the urogenital tract...