mycoplasma agalactiae

Summary

Summary: A species of gram-negative bacteria causing contagious agalactia of SHEEP and GOATS.

Top Publications

  1. Chopra Dewasthaly R, Marenda M, Rosengarten R, Jechlinger W, Citti C. Construction of the first shuttle vectors for gene cloning and homologous recombination in Mycoplasma agalactiae. FEMS Microbiol Lett. 2005;253:89-94 pubmed
    b>Mycoplasma agalactiae is a worldwide ruminant pathogen that causes significant economic losses by inflicting contagious agalactia in sheep and goats...
  2. Assunção P, de la Fe C, Ramirez A, Andrada M, Poveda J. Serological study of contagious agalactia in herds of goats in the Canary Islands. Vet Rec. 2004;154:684-7 pubmed
    An indirect ELISA, using local strains of Mycoplasma agalactiae and Mycoplasma mycoides subspecies mycoides large colony (MmmLC), was applied to evaluate the seroprevalence of M agalactiae and MmmLC in flocks of goats on each of the ..
  3. Marenda M, Vilei E, Poumarat F, Frey J, Berthelot X. Validation of the suppressive subtractive hybridization method in Mycoplasma agalactiae species by the comparison of a field strain with the type strain PG2. Vet Res. 2004;35:199-212 pubmed
    ..in one genome (tester) but not in the other (driver), is a promising technique for the comparison of Mycoplasma agalactiae pathogenic strains. The optimal conditions for SSH were established by subtracting the M...
  4. Kittelberger R, O Keefe J, Meynell R, Sewell M, Rosati S, Lambert M, et al. Comparison of four diagnostic tests for the identification of serum antibodies in small ruminants infected with Mycoplasma agalactiae. N Z Vet J. 2006;54:10-5 pubmed
    ..capability of a newly developed Western blot (WB) assay for the detection of serum antibodies against Mycoplasma agalactiae compared with conventional serological tests, and to identify the best test for routine diagnostic use.
  5. de la Fe C, Amores J, Martín A, Sanchez A, Contreras A, Corrales J. Mycoplasma agalactiae detected in the semen of goat bucks. Theriogenology. 2009;72:1278-81 pubmed publisher
    ..Future studies should investigate whether semen could be a real source of CA infection by determining if the agent may be transmitted during natural service or when semen is used for artificial insemination...
  6. Foddai A, Idini G, Fusco M, Rosa N, de la Fe C, Zinellu S, et al. Rapid differential diagnosis of Mycoplasma agalactiae and Mycoplasma bovis based on a multiplex-PCR and a PCR-RFLP. Mol Cell Probes. 2005;19:207-12 pubmed
    ..mb-mp81) of Mycoplasma bovis was cloned, sequenced and compared to membrane-protein 81 gene (ma-mp81) of Mycoplasma agalactiae. After alignment of both sequences, specific primers pairs were designed from variable or unchanging ..
  7. Cacciotto C, Addis M, Pagnozzi D, Chessa B, Coradduzza E, Carcangiu L, et al. The liposoluble proteome of Mycoplasma agalactiae: an insight into the minimal protein complement of a bacterial membrane. BMC Microbiol. 2010;10:225 pubmed publisher
    ..In this work, the liposoluble protein complement of Mycoplasma agalactiae, a minimal bacterial pathogen causing mastitis, polyarthritis, keratoconjunctivitis, and abortion in small ..
  8. Gómez Martín A, de la Fe C, Amores J, Sanchez A, Contreras A, Paterna A, et al. Anatomic location of Mycoplasma mycoides subsp. capri and Mycoplasma agalactiae in naturally infected goat male auricular carriers. Vet Microbiol. 2012;157:355-62 pubmed publisher
    ..In the case of M. agalactiae, colonization seemed to be independent of the animal's auricular carrier state...
  9. Nouvel L, Marenda M, Glew M, Sagné E, Giammarinaro P, Tardy F, et al. Molecular typing of Mycoplasma agalactiae: tracing European-wide genetic diversity and an endemic clonal population. Comp Immunol Microbiol Infect Dis. 2012;35:487-96 pubmed publisher
    b>Mycoplasma agalactiae causes chronic infections in small ruminants and remains endemic in many regions of the world, despite intensive and costly eradication programs. In this study, the innate genomic plasticity of M...

More Information

Publications74

  1. Skapski A, Hygonenq M, Sagné E, Guiral S, Citti C, Baranowski E. Genome-scale analysis of Mycoplasma agalactiae loci involved in interaction with host cells. PLoS ONE. 2011;6:e25291 pubmed publisher
    b>Mycoplasma agalactiae is an important pathogen of small ruminants, in which it causes contagious agalactia...
  2. Amores J, Sanchez A, Martín A, Corrales J, Contreras A, de la Fe C. Viability of Mycoplasma agalactiae and Mycoplasma mycoides subsp. capri in goat milk samples stored under different conditions. Vet Microbiol. 2010;145:347-50 pubmed publisher
    ..Given the different sensitivity of the two mycoplasma species to BR, refrigerated milk samples treated with AZ could be used to detect infections caused by both species through culture-based methods...
  3. Tardy F, Baranowski E, Nouvel L, Mick V, Manso Silvan L, Thiaucourt F, et al. Emergence of atypical Mycoplasma agalactiae strains harboring a new prophage and associated with an alpine wild ungulate mortality episode. Appl Environ Microbiol. 2012;78:4659-68 pubmed publisher
    The bacterium Mycoplasma agalactiae is responsible for contagious agalactia (CA) in small domestic ruminants, a syndrome listed by the World Organization for Animal Health and responsible for severe damage to the dairy industry...
  4. LoRusso A, Decaro N, Greco G, Corrente M, Fasanella A, Buonavoglia D. A real-time PCR assay for detection and quantification of Mycoplasma agalactiae DNA. J Appl Microbiol. 2007;103:918-23 pubmed
    The aim of this study was to develop a rapid, sensitive, specific tool for detection and quantification of Mycoplasma agalactiae DNA in sheep milk samples.
  5. Dordet Frisoni E, Marenda M, Sagné E, Nouvel L, Guérillot R, Glaser P, et al. ICEA of Mycoplasma agalactiae: a new family of self-transmissible integrative elements that confers conjugative properties to the recipient strain. Mol Microbiol. 2013;89:1226-39 pubmed publisher
    ..Using the model pathogen Mycoplasma agalactiae, we demonstrated for the first time that one of these elements, ICEA, is indeed self-transmissible...
  6. Fusco M, Corona L, Onni T, Marras E, Longheu C, Idini G, et al. Development of a sensitive and specific enzyme-linked immunosorbent assay based on recombinant antigens for rapid detection of antibodies against Mycoplasma agalactiae in sheep. Clin Vaccine Immunol. 2007;14:420-5 pubmed
    ..immunosorbent assay (rELISA) for serodiagnosis of contagious agalactia (CA), a disease caused by Mycoplasma agalactiae in sheep and goats. The assay is based on two M. agalactiae surface proteins, namely, P80 and P55...
  7. Nouvel L, Marenda M, Sirand Pugnet P, Sagné E, Glew M, Mangenot S, et al. Occurrence, plasticity, and evolution of the vpma gene family, a genetic system devoted to high-frequency surface variation in Mycoplasma agalactiae. J Bacteriol. 2009;191:4111-21 pubmed publisher
    b>Mycoplasma agalactiae, an important pathogen of small ruminants, exhibits a very versatile surface architecture by switching multiple, related lipoproteins (Vpmas) on and off...
  8. de la Fe C, Assunçao P, Saavedra P, Ramirez A, Poveda J. Field trial of a combined vaccine against caprine contagious agalactia: humoral immune response in lactating goats. Vet J. 2007;174:610-5 pubmed
    Two vaccines against Mycoplasma agalactiae and Mycoplasma mycoides subsp. mycoides (large colony type) were developed using inactivated strains selected in previous characterization studies...
  9. Chopra Dewasthaly R, Zimmermann M, Rosengarten R, Citti C. First steps towards the genetic manipulation of Mycoplasma agalactiae and Mycoplasma bovis using the transposon Tn4001mod. Int J Med Microbiol. 2005;294:447-53 pubmed
    b>Mycoplasma agalactiae and M. bovis rank amongst the most serious pathogenic mycoplasmas infecting small ruminants and cattle, respectively...
  10. Marenda M, Sagne E, Poumarat F, Citti C. Suppression subtractive hybridization as a basis to assess Mycoplasma agalactiae and Mycoplasma bovis genomic diversity and species-specific sequences. Microbiology. 2005;151:475-89 pubmed
    The phylogenically related Mycoplasma agalactiae and Mycoplasma bovis species are two ruminant pathogens difficult to differentiate and for which a limited amount of sequence data are available...
  11. Amores J, Gómez Martín A, Corrales J, Sanchez A, Contreras A, de la Fe C. Presence of contagious agalactia causing mycoplasmas in Spanish goat artificial insemination centres. Theriogenology. 2011;75:1265-70 pubmed publisher
    ..These findings have already prompted efficient measures to detect and avoid the entry of these carriers in Spanish centres. We recommend similar measures for all centres in areas where CA is endemic...
  12. Breton M, Sagne E, Duret S, Beven L, Citti C, Renaudin J. First report of a tetracycline-inducible gene expression system for mollicutes. Microbiology. 2010;156:198-205 pubmed publisher
    ..gene expression in two mollicutes, the plant pathogen Spiroplasma citri and the animal pathogen Mycoplasma agalactiae. An S...
  13. Baranowski E, Guiral S, Sagné E, Skapski A, Citti C. Critical role of dispensable genes in Mycoplasma agalactiae interaction with mammalian cells. Infect Immun. 2010;78:1542-51 pubmed publisher
    ..with mammalian cells, we produced a library of transposon knockout mutants in the ruminant pathogen Mycoplasma agalactiae and used this library to identify mutants displaying a growth-deficient pheonotype in cell culture. M...
  14. Oravcová K, López Enríquez L, Rodríguez Lázaro D, Hernandez M. Mycoplasma agalactiae p40 Gene, a novel marker for diagnosis of contagious agalactia in sheep by real-time PCR: assessment of analytical performance and in-house validation using naturally contaminated milk samples. J Clin Microbiol. 2009;47:445-50 pubmed publisher
    We evaluated the capacity of the Mycoplasma agalactiae p40 gene as a diagnostic marker for contagious agalactia in sheep by quantitative real-time PCR...
  15. Castro Alonso A, Rodriguez F, de la Fe C, Espinosa de los Monteros A, Poveda J, Andrada M, et al. Correlating the immune response with the clinical-pathological course of persistent mastitis experimentally induced by Mycoplasma agalactiae in dairy goats. Res Vet Sci. 2009;86:274-80 pubmed publisher
    ..right mammary glands of 15 lactating goats were inoculating with 10(10) colony-forming units (cfu) of Mycoplasma agalactiae (Ma)...
  16. Chopra Dewasthaly R, Citti C, Glew M, Zimmermann M, Rosengarten R, Jechlinger W. Phase-locked mutants of Mycoplasma agalactiae: defining the molecular switch of high-frequency Vpma antigenic variation. Mol Microbiol. 2008;67:1196-210 pubmed publisher
    b>Mycoplasma agalactiae, an important pathogen of small ruminants, exhibits antigenic diversity by switching the expression of multiple surface lipoproteins called Vpmas (Variable proteins of M. agalactiae)...
  17. Chopra Dewasthaly R, Baumgartner M, Gamper E, Innerebner C, Zimmermann M, Schilcher F, et al. Role of Vpma phase variation in Mycoplasma agalactiae pathogenesis. FEMS Immunol Med Microbiol. 2012;66:307-22 pubmed publisher
    ..Vpma surface lipoproteins of the ruminant pathogen Mycoplasma agalactiae are encoded on a genomic pathogenicity island-like locus and are considered as one of the well-..
  18. Antunes N, Tavio M, Assunção P, Rosales R, Poveda C, de la Fe C, et al. In vitro susceptibilities of field isolates of Mycoplasma agalactiae. Vet J. 2008;177:436-8 pubmed
    ..widespread antibiotic resistance has become to standard treatments, the in vitro susceptibilities of 28 Mycoplasma agalactiae Spanish field isolates to 16 antimicrobial agents were determined using a broth microdilution method...
  19. Sirand Pugnet P, Lartigue C, Marenda M, Jacob D, Barré A, Barbe V, et al. Being pathogenic, plastic, and sexual while living with a nearly minimal bacterial genome. PLoS Genet. 2007;3:e75 pubmed
    ..In this study, the genome of the ruminant pathogen Mycoplasma agalactiae was sequenced...
  20. Assunçao P, Antunes N, Rosales R, Poveda C, Poveda J, Davey H. Flow cytometric determination of the effects of antibacterial agents on Mycoplasma agalactiae, Mycoplasma putrefaciens, Mycoplasma capricolum subsp. capricolum, and Mycoplasma mycoides subsp. mycoides large colony type. Antimicrob Agents Chemother. 2006;50:2845-9 pubmed
    ..Inhibition of mycoplasma growth could be detected by as early as 3 h after the start of treatment. The strongest effect was observed with enrofloxacin- and ciprofloxacin-treated cells...
  21. Giangaspero M, Nicholas R, Hlusek M, Bonfini B, Osawa T, Orusa R, et al. Seroepidemiological survey of sheep flocks from Northern Japan for Mycoplasma ovipneumoniae and Mycoplasma agalactiae. Trop Anim Health Prod. 2012;44:395-8 pubmed publisher
    ..Aomori, three northern prefectures of Japan, were screened for antibodies to Mycoplasma ovipneumoniae and Mycoplasma agalactiae by ELISA. Sixty four animals out of 246 (26%) were seropositive to M...
  22. Verbisck Bucker G, González Candela M, Galián J, Cubero Pablo M, Martín Atance P, León Vizcaíno L. Epidemiology of Mycoplasma agalactiae infection in free-ranging Spanish ibex (Capra pyrenaica) in Andalusia, southern Spain. J Wildl Dis. 2008;44:369-80 pubmed
    b>Mycoplasma agalactiae is the main causal agent of contagious agalactia syndrome in Spain...
  23. Bashiruddin J, Frey J, Königsson M, Johansson K, Hotzel H, Diller R, et al. Evaluation of PCR systems for the identification and differentiation of Mycoplasma agalactiae and Mycoplasma bovis: a collaborative trial. Vet J. 2005;169:268-75 pubmed
    Diagnostic differentiation between the ruminant pathogens Mycoplasma agalactiae and Mycoplasma bovis is known to be problematic when only conventional serological and biochemical tests are used...
  24. McAuliffe L, Churchward C, Lawes J, Loria G, Ayling R, Nicholas R. VNTR analysis reveals unexpected genetic diversity within Mycoplasma agalactiae, the main causative agent of contagious agalactia. BMC Microbiol. 2008;8:193 pubmed publisher
    b>Mycoplasma agalactiae is the main cause of contagious agalactia, a serious disease of sheep and goats, which has major clinical and economic impacts. Previous studies of M...
  25. Chessa B, Pittau M, Puricelli M, Zobba R, Coradduzza E, Dall ara P, et al. Genetic immunization with the immunodominant antigen P48 of Mycoplasma agalactiae stimulates a mixed adaptive immune response in BALBc mice. Res Vet Sci. 2009;86:414-20 pubmed publisher
    A DNA vaccine against contagious agalactia was developed for the first time, encoding the P48 of Mycoplasma agalactiae. Specific immune responses elicited in BALB/c mice were evaluated...
  26. Czurda S, Jechlinger W, Rosengarten R, Chopra Dewasthaly R. Xer1-mediated site-specific DNA inversions and excisions in Mycoplasma agalactiae. J Bacteriol. 2010;192:4462-73 pubmed publisher
    Surface antigen variation in Mycoplasma agalactiae, the etiologic agent of contagious agalactia in sheep and goats, is governed by site-specific recombination within the vpma multigene locus encoding the Vpma family of variable surface ..
  27. de la Fe C, Assunção P, Rosales R, Antunes T, Poveda J. Characterisation of protein and antigen variability among Mycoplasma mycoides subsp. mycoides (LC) and Mycoplasma agalactiae field strains by SDS-PAGE and immunoblotting. Vet J. 2006;171:532-8 pubmed
    Mycoplasma mycoides subsp. mycoides (LC) (Mmm LC) and Mycoplasma agalactiae are the most important mycoplasma species involved in the contagious agalactia syndrome...
  28. Gil M, Pena F, Hermoso De Mendoza J, Gomez L. Genital lesions in an outbreak of caprine contagious agalactia caused by Mycoplasma agalactiae and Mycoplasma putrefaciens. J Vet Med B Infect Dis Vet Public Health. 2003;50:484-7 pubmed
    ..Extremadura region of southwestern Spain, following an outbreak of contagious agalactia syndrome caused by Mycoplasma agalactiae and M. putrefaciens. Although both species were isolated from several organs, M...
  29. Manso Silvan L, Dupuy V, Lysnyansky I, Ozdemir U, Thiaucourt F. Phylogeny and molecular typing of Mycoplasma agalactiae and Mycoplasma bovis by multilocus sequencing. Vet Microbiol. 2012;161:104-12 pubmed publisher
    b>Mycoplasma agalactiae and Mycoplasma bovis are important pathogens producing similar pathologies in small ruminants and cattle, respectively...
  30. Fitzmaurice J, Sewell M, King C, McDougall S, McDonald W, O Keefe J. A real-time polymerase chain reaction assay for the detection of Mycoplasma agalactiae. N Z Vet J. 2008;56:233-6 pubmed publisher
    To develop a real-time PCR for the detection of Mycoplasma agalactiae, using PCR primers targeting the ma-mp81 gene.
  31. Khan L, Miles R, Nicholas R. Hydrogen peroxide production by Mycoplasma bovis and Mycoplasma agalactiae and effect of in vitro passage on a Mycoplasma bovis strain producing high levels of H2O2. Vet Res Commun. 2005;29:181-8 pubmed
    ..bovis strain, this alteration has been shown by SDS-PAGE to be associated with a loss of specific protein production. Further study of these phenomena is essential background for the production of more efficient vaccines for mycoplasmas...
  32. Marenda M, Barbe V, Gourgues G, Mangenot S, Sagne E, Citti C. A new integrative conjugative element occurs in Mycoplasma agalactiae as chromosomal and free circular forms. J Bacteriol. 2006;188:4137-41 pubmed
    An integrative conjugative element, ICEA, was characterized in Mycoplasma agalactiae strain 5632, in which it occurs as multiple chromosomal copies and as a free circular form. The distribution of ICEA sequences in M...
  33. Addis M, Pisanu S, Ghisaura S, Pagnozzi D, Marogna G, Tanca A, et al. Proteomics and pathway analyses of the milk fat globule in sheep naturally infected by Mycoplasma agalactiae provide indications of the in vivo response of the mammary epithelium to bacterial infection. Infect Immun. 2011;79:3833-45 pubmed publisher
    ..factor (NSAF) approach, Western blotting, and pathway analysis, using sheep naturally infected by Mycoplasma agalactiae. A number of protein classes were found to increase in MFGs upon infection, including proteins involved in ..
  34. Cacciotto C, Addis M, Coradduzza E, Carcangiu L, Nuvoli A, Tore G, et al. Mycoplasma agalactiae MAG_5040 is a Mg2+-dependent, sugar-nonspecific SNase recognised by the host humoral response during natural infection. PLoS ONE. 2013;8:e57775 pubmed publisher
    In this study the enzymatic activity of Mycoplasma agalactiae MAG_5040, a magnesium-dependent nuclease homologue to the staphylococcal SNase was characterized and its antigenicity during natural infections was established...
  35. Nouvel L, Sirand Pugnet P, Marenda M, Sagné E, Barbe V, Mangenot S, et al. Comparative genomic and proteomic analyses of two Mycoplasma agalactiae strains: clues to the macro- and micro-events that are shaping mycoplasma diversity. BMC Genomics. 2010;11:86 pubmed publisher
    ..The recent sequencing of the genome of the Mycoplasma agalactiae type strain has challenged our general view on mycoplasmas by suggesting that these simple bacteria are ..
  36. Thomas A, Linden A, Mainil J, Bischof D, Frey J, Vilei E. Mycoplasma bovis shares insertion sequences with Mycoplasma agalactiae and Mycoplasma mycoides subsp. mycoides SC: Evolutionary and developmental aspects. FEMS Microbiol Lett. 2005;245:249-55 pubmed
    Three new insertion elements, ISMbov1, ISMbov2 and ISMbov3, which are closely related to ISMag1 (Mycoplasma agalactiae), ISMmy1 and IS1634 (both Mycoplasma mycoides subsp...
  37. Al Momani W, Nicholas R, Abo Shehada M. Risk factors associated with Mycoplasma agalactiae infection of small ruminants in northern Jordan. Prev Vet Med. 2008;83:1-10 pubmed
    Serological detection of Mycoplasma agalactiae was carried out in 104 small ruminants flocks consisting of 18 sheep, 27 goat and 59 flocks containing both sheep and goats in northern Jordan between 2002 and 2003...
  38. Lysnyansky I, Yogev D, Levisohn S. Molecular characterization of the Mycoplasma bovis p68 gene, encoding a basic membrane protein with homology to P48 of Mycoplasma agalactiae. FEMS Microbiol Lett. 2008;279:234-42 pubmed publisher
    ..bovis and P48 of Mycoplasma agalactiae. Determination of the genomic distribution of both M...
  39. McAuliffe L, Gosney F, Hlusek M, de Garnica M, Spergser J, Kargl M, et al. Multilocus sequence typing of Mycoplasma agalactiae. J Med Microbiol. 2011;60:803-11 pubmed publisher
    b>Mycoplasma agalactiae is the main cause of contagious agalactia, a serious disease of sheep and goats, which has major clinical and economic impacts...
  40. Jechlinger W, Chopra Dewasthaly R, Glew M, Citti C, Rosengarten R. [Molecular basis of Mycoplasma agalactiae pathogenicity]. Berl Munch Tierarztl Wochenschr. 2004;117:472-9 pubmed
    ..agalactiae genome therefore represents an important breakthrough which sets up the basis for a variety of follow-up studies assessing the role of Vpmas in molecular pathogenesis. ..
  41. La Manna M, Agnone A, Villari S, Puleio R, Vitale M, Nicholas R, et al. Expansion of intracellular IFN-? positive lymphocytes during Mycoplasma agalactiae infection in sheep. Res Vet Sci. 2011;91:e64-7 pubmed publisher
    ..of antigen-specific lymphocytes positive for intracellular IFN-? during the infection of sheep with Mycoplasma agalactiae by culturing peripheral blood mononuclear cells of infected or uninfected animals with irradiated M...
  42. Carta F, Crobu S, Turrini F. Characterization of sodium dodecylsulfate polyacrylamide gel electrophoresis-separated M. agalactiae membrane antigens by mass spectrometry. Eur J Mass Spectrom (Chichester). 2004;10:413-9 pubmed
    ..micro sequence data obtained by MS/MS allowed us to identify LipC, described as one of the most important Mycoplasma agalactiae antigens...
  43. Heidari S, Derakhshandeh A, Firouzi R, Ansari Lari M, Masoudian M, Eraghi V. Molecular detection of Chlamydophila abortus, Coxiella burnetii, and Mycoplasma agalactiae in small ruminants' aborted fetuses in southern Iran. Trop Anim Health Prod. 2018;50:779-785 pubmed publisher
    ..in southern Iran to detect the Chlamydophila abortus and Coxiella burnetii, as zoonotic pathogens, and Mycoplasma agalactiae, as a neglected abortifacient agent in small ruminants' aborted fetuses, by using polymerase chain ..
  44. Hegde S, Zimmermann M, Flöck M, Brunthaler R, Spergser J, Rosengarten R, et al. Genetic loci of Mycoplasma agalactiae involved in systemic spreading during experimental intramammary infection of sheep. Vet Res. 2016;47:106 pubmed
    ..Using Mycoplasma agalactiae as a model we initiated research in this direction by screening a transposon mutant library in the natural ..
  45. Prats van der Ham M, Tatay Dualde J, de la Fe C, Paterna A, Sanchez A, Corrales J, et al. Molecular resistance mechanisms of Mycoplasma agalactiae to macrolides and lincomycin. Vet Microbiol. 2017;211:135-140 pubmed publisher
    ..a remarkable decrease in antimicrobial susceptibility of different animal mycoplasma species, including Mycoplasma agalactiae (M. agalactiae), the main causative agent of contagious agalactia...
  46. Prats van der Ham M, Tatay Dualde J, de la Fe C, Paterna A, Sanchez A, Corrales J, et al. Detecting asymptomatic rams infected with Mycoplasma agalactiae in ovine artificial insemination centers. Theriogenology. 2017;89:324-328.e1 pubmed publisher
    b>Mycoplasma agalactiae (Ma) is the main causative agent of ovine contagious agalactia, which is a serious disease of small ruminants...
  47. Cubeddu T, Cacciotto C, Pisanu S, Tedde V, Alberti A, Pittau M, et al. Cathelicidin production and release by mammary epithelial cells during infectious mastitis. Vet Immunol Immunopathol. 2017;189:66-70 pubmed publisher
    ..were investigated in mammary tissues of ewes infected by Staphylococcus aureus, Streptococcus uberis, or Mycoplasma agalactiae, with a combined approach including immunohistochemistry, immune-colocalization, and fluorescent in situ ..
  48. Gonzalo C, Carriedo J, Beneitez E, Juarez M, De La Fuente L, San Primitivo F. Short communication: bulk tank total bacterial count in dairy sheep: factors of variation and relationship with somatic cell count. J Dairy Sci. 2006;89:549-52 pubmed
    ..23. Programs for improving milk hygiene should be implemented for both total bacterial count and somatic cell count variables at the same time. ..
  49. Prats van der Ham M, Tatay Dualde J, de la Fe C, Paterna A, Sanchez A, Corrales J, et al. Presence of Mycoplasma agalactiae in semen of naturally infected asymptomatic rams. Theriogenology. 2016;86:791-4 pubmed publisher
    The purpose of the present study was to assess the presence of Mycoplasma agalactiae (Ma), the main causative agent of ovine contagious agalactia (CA), in semen of naturally infected rams...
  50. Amores J, Corrales J, Martín A, Sanchez A, Contreras A, de la Fe C. Comparison of culture and PCR to detect Mycoplasma agalactiae and Mycoplasma mycoides subsp. capri in ear swabs taken from goats. Vet Microbiol. 2010;140:105-8 pubmed publisher
    ..08% (for Mmc), respectively. PCR proved to be a rapid and sensitive method for the detection of mycoplasmas in the external ear of asymptomatic carriers. Tools such as this are needed to adopt efficient control measures against CA. ..
  51. Kheirabadi K, Ebrahimi A. Investigation of Mycoplasma agalactiae in milk and conjunctival swab samples from sheep flocks in west central, Iran. Pak J Biol Sci. 2007;10:1346-8 pubmed
    In a study to investigate the current status of Mycoplasma agalactiae infections in sheep flocks in west central, Iran, a total of 54 and 47 conjunctival swab and milk samples were collected from normal healthy ewes of 26 herds, ..
  52. Poumarat F, Gautier Bouchardon A, Bergonier D, Gay E, Tardy F. Diversity and variation in antimicrobial susceptibility patterns over time in Mycoplasma agalactiae isolates collected from sheep and goats in France. J Appl Microbiol. 2016;120:1208-18 pubmed publisher
    b>Mycoplasma agalactiae is responsible for Contagious Agalactia, a severe syndrome affecting small ruminants worldwide and resulting in significant economic losses in countries with an important dairy industry...
  53. Cheema P, Singh S, Kathiresan S, Kumar R, Bhanot V, Singh V. Synthesis of Recombinant P48 of Mycoplasma agalactiae by Site Directed Mutagenesis and its Immunological Characterization. Anim Biotechnol. 2017;28:11-17 pubmed publisher
    Contagious agalactia caused by Mycoplasma agalactiae is an economically important disease of sheep and goats and has been prevalent worldwide including India. The present study was undertaken to evaluate the membrane protein P48 of M...
  54. Castro Alonso A, de la Fe C, Espinosa de los Monteros A, Rodriguez F, Andrada M, Poveda J, et al. Chronological and immunohistochemical characterization of the mammary immunoinflammatory response in experimental caprine contagious agalactia. Vet Immunol Immunopathol. 2010;136:43-54 pubmed publisher
    To explore the pathogenesis of caprine contagious agalactia (CA), we assessed the ability of Mycoplasma agalactiae (Ma) to modulate the immune system in host tissues by immunohistochemically and chronologically characterizing the main ..
  55. de Garnica M, Rosales R, Gonzalo C, Santos J, Nicholas R. Isolation, molecular characterization and antimicrobial susceptibilities of isolates of Mycoplasma agalactiae from bulk tank milk in an endemic area of Spain. J Appl Microbiol. 2013;114:1575-81 pubmed publisher
    To isolate and characterize strains of Mycoplasma agalactiae from bulk tank and silo ewes' milk.
  56. Paterna A, Sanchez A, Amores J, Gómez Martín A, Corrales J, Contreras A, et al. Survival of Mycoplasma agalactiae and Mycoplasma mycoides subspecies capri in heat treated goat colostrum. Vet J. 2013;196:263-5 pubmed publisher
    The viability of Mycoplasma agalactiae and Mycoplasma mycoides subsp. capri (Mmc) was assessed in goat colostrum treated at different temperatures. Samples of colostrum were inoculated with reference strains of M...
  57. Buonavoglia D, Greco G, Corrente M, Greco M, D Abramo M, Latronico F, et al. Long-term immunogenicity and protection against Mycoplasma agalactiae induced by an oil adjuvant vaccine in sheep. Res Vet Sci. 2010;88:16-9 pubmed publisher
    The long-term protective immunity of an inactivated mineral-oil adjuvanted Mycoplasma agalactiae vaccine was evaluated in sheep...
  58. Alberti A, Robino P, Chessa B, Rosati S, Addis M, Mercier P, et al. Characterisation of Mycoplasma capricolum P60 surface lipoprotein and its evaluation in a recombinant ELISA. Vet Microbiol. 2008;128:81-9 pubmed
    ..domains suggested a structural and functional relationship with the immunodominant antigen P48 of Mycoplasma agalactiae, a basic membrane protein...
  59. Assunçao P, Rosales R, Rifatbegović M, Antunes N, de la Fe C, Ruiz de Galarreta C, et al. Quantification of mycoplasmas in broth medium with sybr green-I and flow cytometry. Front Biosci. 2006;11:492-7 pubmed
    ..These findings suggest that FC can be a good alternative to replace other time-consuming techniques that are currently used to enumerate mycoplasmas in broth medium...
  60. Poumarat F, Le Grand D, Gaurivaud P, Gay E, Chazel M, Game Y, et al. Comparative assessment of two commonly used commercial ELISA tests for the serological diagnosis of contagious agalactia of small ruminants caused by Mycoplasma agalactiae. BMC Vet Res. 2012;8:109 pubmed publisher
    Contagious agalactia (CA) of sheep and goats caused by Mycoplasma agalactiae is a widely occurring economically important disease that is difficult to control...
  61. Verbisck G, González Candela M, Cubero M, Leon L, Serrano E, Perales A. Mycoplasma agalactiae in Iberian ibex (Capra pyrenaica) in Spain. Vet Rec. 2010;167:425-6 pubmed publisher
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    ..As a result, dry therapy was proposed as the main tool to reduce BTSCC. Optimization of milking-machine standards and parlor systems also improved udder health in dairy sheep...
  63. de la Fe C, Gómez Martín A, Amores J, Corrales J, Sanchez A, Poveda J, et al. Latent infection of male goats with Mycoplasma agalactiae and Mycoplasma mycoides subspecies capri at an artificial insemination centre. Vet J. 2010;186:113-5 pubmed publisher
    Contagious agalactia affects goats and is caused by several species of mycoplasma including Mycoplasma agalactiae and Mycoplasma mycoides subsp. capri (Mmc). Male goats, latently infected with M...
  64. Buonavoglia D, Greco G, Quaranta V, Corrente M, Martella V, Decaro N. An oil-emulsion vaccine induces full-protection against Mycoplasma agalactiae infection in sheep. New Microbiol. 2008;31:117-23 pubmed
    The immunogenicity and efficacy of three inactivated vaccines (A, B, C) prepared with Mycoplasma agalactiae (M. agalactiae) and with different oil-emulsion adjuvants were evaluated in sheep...
  65. Marin D, Taranu I, Pascale F, Lionide A, Burlacu R, Bailly J, et al. Sex-related differences in the immune response of weanling piglets exposed to low doses of fumonisin extract. Br J Nutr. 2006;95:1185-92 pubmed
    ..verticillioides culture material. At day 7 and day 21, animals were immunised subcutaneously with a Mycoplasma agalactiae vaccine...