wolbachia

Summary

Summary: A genus of bacteria comprised of a heterogenous group of gram-negative small rods and coccoid forms associated with arthropods. (From Bergey's Manual of Systematic Bacteriology, vol 1, 1984)

Top Publications

  1. Nakamura Y, Gotoh T, Imanishi S, Mita K, Kurtti T, Noda H. Differentially expressed genes in silkworm cell cultures in response to infection by Wolbachia and Cardinium endosymbionts. Insect Mol Biol. 2011;20:279-89 pubmed publisher
    b>Wolbachia and Cardinium are bacterial endosymbionts that are widely distributed amongst arthropods. Both cause reproductive alterations, such as cytoplasmic incompatibility, parthenogenesis and feminization...
  2. Chevalier F, Herbinière Gaboreau J, Bertaux J, Raimond M, Morel F, Bouchon D, et al. The immune cellular effectors of terrestrial isopod Armadillidium vulgare: meeting with their invaders, Wolbachia. PLoS ONE. 2011;6:e18531 pubmed publisher
    ..The latter are also infected at a high prevalence with Wolbachia, an endosymbiotic bacterium which affects the host immune system, possibly to improve its transmission...
  3. Yun Y, Peng Y, Liu F, Lei C. Wolbachia screening in spiders and assessment of horizontal transmission between predator and prey. Neotrop Entomol. 2011;40:164-9 pubmed
    Recent studies have revealed that the prevalence of Wolbachia in arthropods is attributable not only to its vertical transmission, but also to its horizontal transfer...
  4. Duron O. Lateral transfers of insertion sequences between Wolbachia, Cardinium and Rickettsia bacterial endosymbionts. Heredity (Edinb). 2013;111:330-7 pubmed publisher
    ..transfers were recently shown to have a pivotal role in the evolution of the most common of these endosymbionts, Wolbachia, the present study show that inter-generic DNA transfers also commonly take place, constituting a potent source ..
  5. Walker T, Johnson P, Moreira L, Iturbe Ormaetxe I, Frentiu F, McMeniman C, et al. The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations. Nature. 2011;476:450-3 pubmed publisher
    ..It has been proposed that endosymbiotic bacterial Wolbachia infections of insects might be used in novel strategies for dengue control...
  6. Tulgetske G, Stouthamer R. Characterization of intersex production in Trichogramma kaykai infected with parthenogenesis-inducing Wolbachia. Naturwissenschaften. 2012;99:143-52 pubmed publisher
    ..In parasitoid wasps of the genus Trichogramma, such individuals typically appear as a result of rearing Wolbachia-infected thelytokous wasps at high temperatures...
  7. Lefoulon E, Gavotte L, Junker K, Barbuto M, Uni S, Landmann F, et al. A new type F Wolbachia from Splendidofilariinae (Onchocercidae) supports the recent emergence of this supergroup. Int J Parasitol. 2012;42:1025-36 pubmed publisher
    b>Wolbachia are vertically transmitted endosymbiotic bacteria of arthropods and onchocercid nematodes. It is commonly accepted that they co-evolved with their filarial hosts, and have secondarily been lost in some species...
  8. Bowman D. Introduction to the alpha-proteobacteria: Wolbachia and Bartonella, Rickettsia, Brucella, Ehrlichia, and Anaplasma. Top Companion Anim Med. 2011;26:173-7 pubmed publisher
    b>Wolbachia is an obligate intracellular endosymbiont and likely mutualist living within the heartworm Dirofilaria immitis and a number of other filarial nematodes in the family Onchocercidae...
  9. Serbus L, Ferreccio A, Zhukova M, McMorris C, Kiseleva E, Sullivan W. A feedback loop between Wolbachia and the Drosophila gurken mRNP complex influences Wolbachia titer. J Cell Sci. 2011;124:4299-308 pubmed publisher
    ..b>Wolbachia endosymbionts are globally dispersed throughout most insect species and are the causative agent in filarial ..

More Information

Publications144 found, 100 shown here

  1. Sekeyova Z, Mediannikov O, Roux V, Subramanian G, Spitalska E, Kristofík J, et al. Identification of Rickettsia africae and Wolbachia sp. in Ceratophyllus garei fleas from Passerine birds migrated from Africa. Vector Borne Zoonotic Dis. 2012;12:539-43 pubmed publisher
    ..scirpaceus. Moreover, two Wolbachia sp. were also detected in fleas. This is the first record of R. africae and Wolbachia sp...
  2. Lentz C, Halls V, Hannam J, Niebel B, Strübing U, Mayer G, et al. A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro. Chem Biol. 2013;20:177-87 pubmed publisher
    ..Endosymbiotic ?-proteobacteria Wolbachia are essential for these parasites throughout their life cycle...
  3. Moretti R, Calvitti M. Male mating performance and cytoplasmic incompatibility in a wPip Wolbachia trans-infected line of Aedes albopictus (Stegomyia albopicta). Med Vet Entomol. 2013;27:377-86 pubmed publisher
    b>Wolbachia pipientis Hertig (Rickettsiales: Rickettsiaceae) is a maternally inherited endosymbiont of a large number of insects and other arthropods that induces various effects on host reproductive biology...
  4. Yu M, Zhang K, Xue X, Hong X. Effects of Wolbachia on mtDNA variation and evolution in natural populations of Tetranychus urticae Koch. Insect Mol Biol. 2011;20:311-21 pubmed publisher
    We investigated the effects of Wolbachia infection on mtDNA variation in spider mites by sequencing a portion of the mitochondrial cytochrome oxidase I (COI) gene from 198 individuals of known infection status...
  5. Hoffmann A, Turelli M. Facilitating Wolbachia introductions into mosquito populations through insecticide-resistance selection. Proc Biol Sci. 2013;280:20130371 pubmed publisher
    b>Wolbachia infections are being introduced into mosquito vectors of human diseases following the discovery that they can block transmission of disease agents...
  6. Bian G, Joshi D, Dong Y, Lu P, Zhou G, Pan X, et al. Wolbachia invades Anopheles stephensi populations and induces refractoriness to Plasmodium infection. Science. 2013;340:748-51 pubmed publisher
    b>Wolbachia is a maternally transmitted symbiotic bacterium of insects that has been proposed as a potential agent for the control of insect-transmitted diseases...
  7. Rossi M, Aguiar Alves F, Santos S, Paiva J, Bendas A, Fernandes O, et al. Detection of Wolbachia DNA in blood from dogs infected with Dirofilaria immitis. Exp Parasitol. 2010;126:270-2 pubmed publisher
    ..It harbors a symbiotic intracellular bacterium from the genus Wolbachia that plays an important role in its biology and contributes to the inflammatory pathology of the heartworm...
  8. Yun Y, Lei C, Peng Y, Liu F, Chen J, Chen L. Wolbachia strains typing in different geographic population spider, Hylyphantes graminicola (Linyphiidae). Curr Microbiol. 2011;62:139-45 pubmed publisher
    The Wolbachia endosymbiont of spiders has not been extensively examined...
  9. McNulty S, Abubucker S, Simon G, Mitreva M, McNulty N, Fischer K, et al. Transcriptomic and proteomic analyses of a Wolbachia-free filarial parasite provide evidence of trans-kingdom horizontal gene transfer. PLoS ONE. 2012;7:e45777 pubmed publisher
    Most filarial parasites in the subfamilies Onchocercinae and Dirofilariinae depend on Wolbachia endobacteria to successfully carry out their life cycle...
  10. Osei Amo S, Hussain M, O Neill S, Asgari S. Wolbachia-induced aae-miR-12 miRNA negatively regulates the expression of MCT1 and MCM6 genes in Wolbachia-infected mosquito cell line. PLoS ONE. 2012;7:e50049 pubmed publisher
    Best recognized for its role in manipulating host reproduction, the parasitic gram-negative Wolbachia pipientis is known to colonize a wide range of invertebrates...
  11. Rodriguero M, Lanteri A, Confalonieri V. Mito-nuclear genetic comparison in a Wolbachia infected weevil: insights on reproductive mode, infection age and evolutionary forces shaping genetic variation. BMC Evol Biol. 2010;10:340 pubmed publisher
    Maternally inherited endosymbionts like Wolbachia pipientis are in linkage disequilibrium with the mtDNA of their hosts. Therefore, they can induce selective sweeps, decreasing genetic diversity over many generations...
  12. Augustinos A, Santos Garcia D, Dionyssopoulou E, Moreira M, Papapanagiotou A, Scarvelakis M, et al. Detection and characterization of Wolbachia infections in natural populations of aphids: is the hidden diversity fully unraveled?. PLoS ONE. 2011;6:e28695 pubmed publisher
    ..One of the key symbionts in arthropods is Wolbachia, an ?-Proteobacterium implicated in many important biological processes and believed to be a potential tool for ..
  13. Hughes G, VEGA RODRIGUEZ J, Xue P, Rasgon J. Wolbachia strain wAlbB enhances infection by the rodent malaria parasite Plasmodium berghei in Anopheles gambiae mosquitoes. Appl Environ Microbiol. 2012;78:1491-5 pubmed publisher
    b>Wolbachia, a common bacterial endosymbiont of insects, has been shown to protect its hosts against a wide range of pathogens. However, not all strains exert a protective effect on their host...
  14. Xiao J, Wang N, Murphy R, Cook J, Jia L, Huang D. Wolbachia infection and dramatic intraspecific mitochondrial DNA divergence in a fig wasp. Evolution. 2012;66:1907-16 pubmed publisher
    Mitochondria and Wolbachia are maternally inherited genomes that exhibit strong linkage disequilibrium in many organisms...
  15. Blagrove M, Arias Goeta C, Di Genua C, Failloux A, Sinkins S. A Wolbachia wMel transinfection in Aedes albopictus is not detrimental to host fitness and inhibits Chikungunya virus. PLoS Negl Trop Dis. 2013;7:e2152 pubmed publisher
    b>Wolbachia inherited intracellular bacteria can manipulate the reproduction of their insect hosts through cytoplasmic incompatibility (CI), and certain strains have also been shown to inhibit the replication or dissemination of viruses...
  16. Guerrero R, Bain O, Martin C, Barbuto M. A new species of Litomosoides (Nematoda: Onchocercidae), parasite of Nectomys palmipes (Rodentia: Cricetidae: Sigmodontinae) from Venezuela: description, molecular evidence, Wolbachia pipientis screening. Folia Parasitol (Praha). 2011;58:149-56 pubmed
    ..used for molecular analysis of the coxI and 12S rDNA genes, and screened for the presence of the endobacterium Wolbachia pipientis...
  17. Moreira L, Iturbe Ormaetxe I, Jeffery J, Lu G, Pyke A, Hedges L, et al. A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium. Cell. 2009;139:1268-78 pubmed publisher
    b>Wolbachia are maternally inherited intracellular bacterial symbionts that are estimated to infect more than 60% of all insect species...
  18. Moreira L, Ye Y, Turner K, Eyles D, McGraw E, O Neill S. The wMelPop strain of Wolbachia interferes with dopamine levels in Aedes aegypti. Parasit Vectors. 2011;4:28 pubmed publisher
    b>Wolbachia is an intracellular bacterium that has been stably transinfected into the mosquito vector of dengue, Aedes aegypti...
  19. Tamarozzi F, Halliday A, Gentil K, Hoerauf A, Pearlman E, Taylor M. Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment. Clin Microbiol Rev. 2011;24:459-68 pubmed publisher
    The discovery of Wolbachia intracellular bacteria within filarial nematodes, including Onchocerca volvulus, the causative agent of onchocerciasis or "river blindness," has delivered a paradigm shift in our understanding of the ..
  20. van den Hurk A, Hall Mendelin S, Pyke A, Frentiu F, McElroy K, Day A, et al. Impact of Wolbachia on infection with chikungunya and yellow fever viruses in the mosquito vector Aedes aegypti. PLoS Negl Trop Dis. 2012;6:e1892 pubmed publisher
    ..When transinfected into Ae. aegypti, the intracellular bacterium Wolbachia has recently been shown to inhibit replication of DENVs, CHIKV, malaria parasites and filarial nematodes, ..
  21. Tortosa P, Charlat S, Labbé P, Dehecq J, Barré H, Weill M. Wolbachia age-sex-specific density in Aedes albopictus: a host evolutionary response to cytoplasmic incompatibility?. PLoS ONE. 2010;5:e9700 pubmed publisher
    b>Wolbachia bacteria have invaded many arthropod species by inducing Cytoplasmic Incompatibility (CI). These symbionts represent fascinating objects of study for evolutionary biologists, but also powerful potential biocontrol agents...
  22. Hansen R, Trees A, Bah G, Hetzel U, Martin C, Bain O, et al. A worm's best friend: recruitment of neutrophils by Wolbachia confounds eosinophil degranulation against the filarial nematode Onchocerca ochengi. Proc Biol Sci. 2011;278:2293-302 pubmed publisher
    ..Both species harbour Wolbachia endosymbionts and are remarkable in that adult female worms remain viable but sessile for many years while ..
  23. Li Z, Carlow C. Characterization of transcription factors that regulate the type IV secretion system and riboflavin biosynthesis in Wolbachia of Brugia malayi. PLoS ONE. 2012;7:e51597 pubmed publisher
    The human filarial parasite Brugia malayi harbors an endosymbiotic bacterium Wolbachia (wBm) that is required for parasite survival. Consequently, targeting wBm is a promising approach for anti-filarial drug development...
  24. Hornett E, Engelstädter J, Hurst G. Hidden cytoplasmic incompatibility alters the dynamics of male-killer/host interactions. J Evol Biol. 2010;23:479-87 pubmed publisher
    b>Wolbachia manipulate the reproduction of their arthropod hosts in a variety of ways...
  25. Desjardins C, Cerqueira G, Goldberg J, Dunning Hotopp J, Haas B, Zucker J, et al. Genomics of Loa loa, a Wolbachia-free filarial parasite of humans. Nat Genet. 2013;45:495-500 pubmed publisher
    ..Unlike most filariae, L. loa does not contain the obligate intracellular Wolbachia endosymbiont. We describe the 91.4-Mb genome of L...
  26. Bian G, Xu Y, Lu P, Xie Y, Xi Z. The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegypti. PLoS Pathog. 2010;6:e1000833 pubmed publisher
    ..The endosymbiotic bacterium Wolbachia has long been promoted as a potential vehicle for introducing disease-resistance genes into mosquitoes, thereby ..
  27. Leclercq S, Giraud I, Cordaux R. Remarkable abundance and evolution of mobile group II introns in Wolbachia bacterial endosymbionts. Mol Biol Evol. 2011;28:685-97 pubmed publisher
    ..Yet, the genomes of Wolbachia, one of the most abundant bacterial endosymbionts on Earth, are littered with transposable elements, in ..
  28. Hoerauf A, Pfarr K, Mand S, Debrah A, Specht S. Filariasis in Africa--treatment challenges and prospects. Clin Microbiol Infect. 2011;17:977-85 pubmed publisher
    ..and Onchocerca volvulus, the species causing LF and onchocerciasis in Africa, live in mutual symbiosis with Wolbachia endobacteria, which cause a major part of the inflammation leading to symptoms and are antibiotic targets for ..
  29. Hoffmann A, Montgomery B, Popovici J, Iturbe Ormaetxe I, Johnson P, Muzzi F, et al. Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission. Nature. 2011;476:454-7 pubmed publisher
    ..Population transformation using the intracellular bacterium Wolbachia is particularly attractive because this maternally-inherited agent provides a powerful mechanism to invade ..
  30. Korten S, Kaifi J, Büttner D, Hoerauf A. Transforming growth factor-beta expression by host cells is elicited locally by the filarial nematode Onchocerca volvulus in hyporeactive patients independently from Wolbachia. Microbes Infect. 2010;12:555-64 pubmed publisher
    ..ivermectin or endobacteria-depleting doxycycline treatment indicates induction to depend on filariae and not on Wolbachia endobacteria. TGF-beta(+) cells were reduced in HIV co-infection...
  31. Barr K, Hearne L, Briesacher S, Clark T, Davis G. Microbial symbionts in insects influence down-regulation of defense genes in maize. PLoS ONE. 2010;5:e11339 pubmed publisher
    ..is the most successful species in its genus and is the only Diabrotica beetle harboring an almost species-wide Wolbachia infection...
  32. Cordaux R, Bouchon D, Greve P. The impact of endosymbionts on the evolution of host sex-determination mechanisms. Trends Genet. 2011;27:332-41 pubmed publisher
    ..They might therefore represent excellent models for studying transitions between sex-determining systems and, more generally, the evolution of sex-determination mechanisms in eukaryotes...
  33. Unckless R, Jaenike J. Maintenance of a male-killing Wolbachia in Drosophila innubila by male-killing dependent and male-killing independent mechanisms. Evolution. 2012;66:678-689 pubmed publisher
    ..We tested these hypotheses in Drosophila innubila, a mycophagous species infected with MK Wolbachia. There was no evidence of horizontal transmission in the wild and no evidence Wolbachia reduced levels of ..
  34. Yang C, Xiao J, Niu L, Ma G, Cook J, Bian S, et al. Chaos of Wolbachia sequences inside the compact fig syconia of Ficus benjamina (Ficus: moraceae). PLoS ONE. 2012;7:e48882 pubmed publisher
    ..Previous surveys of Wolbachia, maternally inherited endosymbiotic bacteria that infect vast numbers of arthropod hosts, showed that fig wasps ..
  35. McNulty S, Fischer K, Curtis K, Weil G, Brattig N, Fischer P. Localization of Wolbachia-like gene transcripts and peptides in adult Onchocerca flexuosa worms indicates tissue specific expression. Parasit Vectors. 2013;6:2 pubmed publisher
    Most filarial species in the genus Onchocerca depend on Wolbachia endobacteria to successfully carry out their life cycle. O...
  36. Richardson M, Weinert L, Welch J, Linheiro R, Magwire M, Jiggins F, et al. Population genomics of the Wolbachia endosymbiont in Drosophila melanogaster. PLoS Genet. 2012;8:e1003129 pubmed publisher
    b>Wolbachia are maternally inherited symbiotic bacteria, commonly found in arthropods, which are able to manipulate the reproduction of their host in order to maximise their transmission...
  37. Le Clec h W, Chevalier F, Genty L, Bertaux J, Bouchon D, Sicard M. Cannibalism and predation as paths for horizontal passage of Wolbachia between terrestrial isopods. PLoS ONE. 2013;8:e60232 pubmed publisher
    The alpha-proteobacteria Wolbachia are the most widespread endosymbionts in arthropods and nematodes...
  38. Stahlhut J, Desjardins C, Clark M, Baldo L, Russell J, Werren J, et al. The mushroom habitat as an ecological arena for global exchange of Wolbachia. Mol Ecol. 2010;19:1940-52 pubmed publisher
    b>Wolbachia infect a variety of arthropod and nematode hosts, but in arthropods, host phylogenetic relationships are usually poor predictors of strain similarity...
  39. Martin C, Gavotte L. The bacteria Wolbachia in filariae, a biological Russian dolls' system: new trends in antifilarial treatments. Parasite. 2010;17:79-89 pubmed
    Filarial nematode species can host Wolbachia bacterial endosymbionts. To understand the symbiosis, a higher level of complexity should be considered, taking in account the tripartite association between Wolbachia, filariae and mammals...
  40. Thierry M, Becker N, Hajri A, Reynaud B, Lett J, Delatte H. Symbiont diversity and non-random hybridization among indigenous (Ms) and invasive (B) biotypes of Bemisia tabaci. Mol Ecol. 2011;20:2172-87 pubmed publisher
    ..aleyrodidarum and potentially six secondary symbionts: Cardinium, Arsenophonus, Hamiltonella, Rickettsia, Wolbachia and Fritschea...
  41. Siozios S, Ioannidis P, Klasson L, Andersson S, Braig H, Bourtzis K. The diversity and evolution of Wolbachia ankyrin repeat domain genes. PLoS ONE. 2013;8:e55390 pubmed publisher
    ..Despite having a reduced genome, the arthropod strains of the alphaproteobacterium Wolbachia contain an unusually high number of ankyrin repeat domain-encoding genes ranging from 23 in wMel to 60 in wPip ..
  42. Calvitti M, Moretti R, Lampazzi E, Bellini R, Dobson S. Characterization of a new Aedes albopictus (Diptera: Culicidae)-Wolbachia pipientis (Rickettsiales: Rickettsiaceae) symbiotic association generated by artificial transfer of the wPip strain from Culex pipiens (Diptera: Culicidae). J Med Entomol. 2010;47:179-87 pubmed
    b>Wolbachia is a maternally inherited endosymbiont inducing various effects in insects and other invertebrate hosts that facilitate the invasion of naive host populations...
  43. Caragata E, Poinsignon A, Moreira L, Johnson P, Leong Y, Ritchie S, et al. Improved accuracy of the transcriptional profiling method of age grading in Aedes aegypti mosquitoes under laboratory and semi-field cage conditions and in the presence of Wolbachia infection. Insect Mol Biol. 2011;20:215-24 pubmed publisher
    ..aegypti, we also tested the model's accuracy for Wolbachia-infected mosquitoes and found no decline in performance...
  44. Casper Lindley C, Kimura S, Saxton D, Essaw Y, Simpson I, Tan V, et al. Rapid fluorescence-based screening for Wolbachia endosymbionts in Drosophila germ line and somatic tissues. Appl Environ Microbiol. 2011;77:4788-94 pubmed publisher
    b>Wolbachia is a globally distributed bacterial endosymbiont present in arthropods and nematodes...
  45. Frost C, Fernández Marín H, Smith J, Hughes W. Multiple gains and losses of Wolbachia symbionts across a tribe of fungus-growing ants. Mol Ecol. 2010;19:4077-85 pubmed publisher
    Although the intracellular bacterium Wolbachia is ubiquitous in insects, it has a unique relationship with New World ants on which particular bacterial strains have specialized...
  46. Gavotte L, Mercer D, Stoeckle J, Dobson S. Costs and benefits of Wolbachia infection in immature Aedes albopictus depend upon sex and competition level. J Invertebr Pathol. 2010;105:341-6 pubmed publisher
    ..An example is provided by obligate, maternally-inherited Wolbachia, which infect a broad range of invertebrates...
  47. Endersby N, Hoffmann A, White V, Ritchie S, Johnson P, Weeks A. Changes in the genetic structure of Aedes aegypti (Diptera: Culicidae) populations in Queensland, Australia, across two seasons: implications for potential mosquito releases. J Med Entomol. 2011;48:999-1007 pubmed
    ..Diptera: Culicidae). Mosquitoes artificially infected with the bacterium, Wolbachia pipientis Hertig, are being assessed as candidates for release at the adult stage with the aim of replacement of ..
  48. Brelsfoard C, Dobson S. Wolbachia effects on host fitness and the influence of male aging on cytoplasmic incompatibility in Aedes polynesiensis (Diptera: Culicidae). J Med Entomol. 2011;48:1008-15 pubmed
    The endosymbiotic bacteria Wolbachia manipulate host reproduction by inducing a form of sterility known as cytoplasmic incompatibility (CI), promoting the invasion of infection into natural host populations...
  49. Schneider D, Garschall K, Parker A, Abd Alla A, Miller W. Global Wolbachia prevalence, titer fluctuations and their potential of causing cytoplasmic incompatibilities in tsetse flies and hybrids of Glossina morsitans subgroup species. J Invertebr Pathol. 2013;112 Suppl:S104-15 pubmed publisher
    ..applicability of a novel VNTR-based (Variable-Number-Tandem-Repeat) molecular screening tool for fingerprinting Wolbachia-infections in tsetse flies...
  50. Mousson L, Zouache K, Arias Goeta C, Raquin V, Mavingui P, Failloux A. The native Wolbachia symbionts limit transmission of dengue virus in Aedes albopictus. PLoS Negl Trop Dis. 2012;6:e1989 pubmed publisher
    ..This mosquito is naturally super-infected with two Wolbachia strains, wAlbA and wAlbB. While Wolbachia does not affect replication of CHIK virus (CHIKV) in Ae...
  51. Zhang G, Hussain M, O Neill S, Asgari S. Wolbachia uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in Aedes aegypti. Proc Natl Acad Sci U S A. 2013;110:10276-81 pubmed publisher
    The endosymbiont Wolbachia is common among insects and known for the reproductive manipulations it exerts on hosts as well as inhibition of virus replication in their hosts...
  52. Hosokawa T, Koga R, Kikuchi Y, Meng X, Fukatsu T. Wolbachia as a bacteriocyte-associated nutritional mutualist. Proc Natl Acad Sci U S A. 2010;107:769-74 pubmed publisher
    ..Facultative and parasitic bacterial symbionts like Wolbachia have been regarded as evolutionarily distinct from such obligate nutritional mutualists...
  53. Strübing U, Lucius R, Hoerauf A, Pfarr K. Mitochondrial genes for heme-dependent respiratory chain complexes are up-regulated after depletion of Wolbachia from filarial nematodes. Int J Parasitol. 2010;40:1193-202 pubmed publisher
    ..Annually, 1.3 billion people are at risk of infection. Targeting the essential Wolbachia endobacteria of filarial nematodes with doxycycline has proven to be an effective therapy resulting in a block ..
  54. McNulty S, Foster J, Mitreva M, Dunning Hotopp J, Martin J, Fischer K, et al. Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer. PLoS ONE. 2010;5:e11029 pubmed publisher
    b>Wolbachia are among the most abundant symbiotic microbes on earth; they are present in about 66% of all insect species, some spiders, mites and crustaceans, and most filarial nematode species...
  55. Fu Y, Gavotte L, Mercer D, Dobson S. Artificial triple Wolbachia infection in Aedes albopictus yields a new pattern of unidirectional cytoplasmic incompatibility. Appl Environ Microbiol. 2010;76:5887-91 pubmed publisher
    Obligately intracellular Wolbachia bacteria infect numerous invertebrates and often manipulate host reproduction to facilitate the spread of infection...
  56. Kondo N, Tuda M, Toquenaga Y, Lan Y, Buranapanichpan S, Horng S, et al. Wolbachia infections in world populations of bean beetles (Coleoptera: Chrysomelidae: Bruchinae) infesting cultivated and wild legumes. Zoolog Sci. 2011;28:501-8 pubmed publisher
    b>Wolbachia endosymbionts are widespread among insects and other arthropods, often causing cytoplasmic incompatibility and other reproductive phenotypes in their hosts...
  57. Melnikow E, Xu S, Liu J, Li L, Oksov Y, Ghedin E, et al. Interaction of a Wolbachia WSP-like protein with a nuclear-encoded protein of Brugia malayi. Int J Parasitol. 2011;41:1053-61 pubmed publisher
    The Brugia malayi endosymbiont Wolbachia has recently been shown to be essential for its host's survival and development...
  58. Rancès E, Ye Y, Woolfit M, McGraw E, O Neill S. The relative importance of innate immune priming in Wolbachia-mediated dengue interference. PLoS Pathog. 2012;8:e1002548 pubmed publisher
    The non-virulent Wolbachia strain wMel and the life-shortening strain wMelPop-CLA, both originally from Drosophila melanogaster, have been stably introduced into the mosquito vector of dengue fever, Aedes aegypti...
  59. Pichon S, Bouchon D, Liu C, Chen L, Garrett R, Greve P. The expression of one ankyrin pk2 allele of the WO prophage is correlated with the Wolbachia feminizing effect in isopods. BMC Microbiol. 2012;12:55 pubmed publisher
    The maternally inherited ?-Proteobacteria Wolbachia pipientis is an obligate endosymbiont of nematodes and arthropods, in which they induce a variety of reproductive alterations, including Cytoplasmic Incompatibility (CI) and ..
  60. Metcalf J, Bordenstein S. The complexity of virus systems: the case of endosymbionts. Curr Opin Microbiol. 2012;15:546-52 pubmed publisher
    ..One endosymbiont, Wolbachia pipientis, infects a vast number of arthropod and nematode species and often has a significant portion of its ..
  61. Andrews E, Crain P, Fu Y, Howe D, Dobson S. Reactive oxygen species production and Brugia pahangi survivorship in Aedes polynesiensis with artificial Wolbachia infection types. PLoS Pathog. 2012;8:e1003075 pubmed publisher
    Heterologous transinfection with the endosymbiotic bacterium Wolbachia has been shown previously to induce pathogen interference phenotypes in mosquito hosts...
  62. Guidolin A, Cônsoli F. Molecular characterization of Wolbachia strains associated with the invasive Asian citrus psyllid Diaphorina citri in Brazil. Microb Ecol. 2013;65:475-86 pubmed publisher
    b>Wolbachia is a symbiont intensively studied due to its ability to interfere with their host's reproduction, and it has been recently proposed as an alternative tool to control insect pests or vectors of diseases...
  63. Glaser R, Meola M. The native Wolbachia endosymbionts of Drosophila melanogaster and Culex quinquefasciatus increase host resistance to West Nile virus infection. PLoS ONE. 2010;5:e11977 pubmed publisher
    The bacterial endosymbiont Wolbachia pipientis has been shown to increase host resistance to viral infection in native Drosophila hosts and in the normally Wolbachia-free heterologous host Aedes aegypti when infected by Wolbachia from ..
  64. Chu D, Gao C, De Barro P, Zhang Y, Wan F, Khan I. Further insights into the strange role of bacterial endosymbionts in whitefly, Bemisia tabaci: comparison of secondary symbionts from biotypes B and Q in China. Bull Entomol Res. 2011;101:477-86 pubmed publisher
    The percentage infection of secondary symbionts (SS) (Wolbachia, Arsenophonus, Rickettsia, Hamiltonella, Fritschea and Cardinium) in the exotic Bemisia tabaci (Genn...
  65. Zheng Y, Ren P, Wang J, Wang Y. Wolbachia-induced cytoplasmic incompatibility is associated with decreased Hira expression in male Drosophila. PLoS ONE. 2011;6:e19512 pubmed publisher
    b>Wolbachia are obligate endosymbiotic bacteria that infect numerous species of arthropods and nematodes...
  66. Bossan B, Koehncke A, Hammerstein P. A new model and method for understanding Wolbachia-induced cytoplasmic incompatibility. PLoS ONE. 2011;6:e19757 pubmed publisher
    b>Wolbachia are intracellular bacteria transmitted almost exclusively vertically through eggs. In response to this mode of transmission, Wolbachia strategically manipulate their insect hosts' reproduction...
  67. Chambers E, Hapairai L, Peel B, Bossin H, Dobson S. Male mating competitiveness of a Wolbachia-introgressed Aedes polynesiensis strain under semi-field conditions. PLoS Negl Trop Dis. 2011;5:e1271 pubmed publisher
    ..Previously, the generation of a novel Aedes polynesiensis strain (CP) infected with an exogenous type of Wolbachia has been described. The CP mosquito is cytoplasmically incompatible (i.e...
  68. Zhang H, Zhang K, Hong X. Population dynamics of noncytoplasmic incompatibility-inducing Wolbachia in Nilaparvata lugens and its effects on host adult life span and female fitness. Environ Entomol. 2010;39:1801-9 pubmed publisher
    b>Wolbachia are bacteria that live intracellularly in a wide variety of arthropods. They are maternally inherited and can affect both reproduction and fitness of its host...
  69. Weiss B, Maltz M, Aksoy S. Obligate symbionts activate immune system development in the tsetse fly. J Immunol. 2012;188:3395-403 pubmed publisher
    ..Our finding that molecular components of Wigglesworthia exhibit immunostimulatory activity within tsetse is representative of a novel evolutionary adaptation that steadfastly links an obligate symbiont with its host...
  70. Vollmer J, Schiefer A, Schneider T, Jülicher K, Johnston K, Taylor M, et al. Requirement of lipid II biosynthesis for cell division in cell wall-less Wolbachia, endobacteria of arthropods and filarial nematodes. Int J Med Microbiol. 2013;303:140-9 pubmed publisher
    Obligate Wolbachia endobacteria have a reduced genome and retained genes are hypothesized to be crucial for survival...
  71. Carrington L, Hoffmann A, Weeks A. Monitoring long-term evolutionary changes following Wolbachia introduction into a novel host: the Wolbachia popcorn infection in Drosophila simulans. Proc Biol Sci. 2010;277:2059-68 pubmed publisher
    b>Wolbachia may act as a biological control agent for pest management; in particular, the Wolbachia variant wMelPop (popcorn) shortens host longevity and may be useful for dengue suppression...
  72. Azpurua J, De La Cruz D, Valderama A, WINDSOR D. Lutzomyia sand fly diversity and rates of infection by Wolbachia and an exotic Leishmania species on Barro Colorado Island, Panama. PLoS Negl Trop Dis. 2010;4:e627 pubmed publisher
    ..a microbe that can potentially serve in vector population control, the cytoplasmically transmitted rickettsia, Wolbachia pipientis...
  73. Majerus T, Majerus M. Intergenomic arms races: detection of a nuclear rescue gene of male-killing in a ladybird. PLoS Pathog. 2010;6:e1000987 pubmed publisher
    ..Consequently, some, particularly bacteria of the genus Wolbachia, employ a variety of strategies that favour female over male hosts...
  74. Sugimoto T, Fujii T, Kayukawa T, Sakamoto H, Ishikawa Y. Expression of a doublesex homologue is altered in sexual mosaics of Ostrinia scapulalis moths infected with Wolbachia. Insect Biochem Mol Biol. 2010;40:847-54 pubmed publisher
    ..In Wolbachia-induced sexual mosaics of O...
  75. Duron O, Raymond M, Weill M. Many compatible Wolbachia strains coexist within natural populations of Culex pipiens mosquito. Heredity (Edinb). 2011;106:986-93 pubmed publisher
    Maternally inherited Wolbachia often manipulate the reproduction of arthropods to promote their transmission...
  76. Shiny C, Krushna N, Babu S, Elango S, Manokaran G, Narayanan R. Recombinant Wolbachia heat shock protein 60 (HSP60) mediated immune responses in patients with lymphatic filariasis. Microbes Infect. 2011;13:1221-31 pubmed publisher
    b>Wolbachia, an endosymbiont present in filarial nematodes, have been implicated in a variety of roles, including the worm development and survival...
  77. Hancock P, Godfray H. Modelling the spread of Wolbachia in spatially heterogeneous environments. J R Soc Interface. 2012;9:3045-54 pubmed
    The endosymbiont Wolbachia infects a large number of insect species and is capable of rapid spread when introduced into a novel host population...
  78. Duplouy A, Iturbe Ormaetxe I, Beatson S, Szubert J, Brownlie J, McMeniman C, et al. Draft genome sequence of the male-killing Wolbachia strain wBol1 reveals recent horizontal gene transfers from diverse sources. BMC Genomics. 2013;14:20 pubmed publisher
    The endosymbiont Wolbachia pipientis causes diverse and sometimes dramatic phenotypes in its invertebrate hosts...
  79. Caragata E, Rancès E, O Neill S, McGraw E. Competition for amino acids between Wolbachia and the mosquito host, Aedes aegypti. Microb Ecol. 2014;67:205-18 pubmed publisher
    The endosymbiont Wolbachia represents a promising method of dengue control, as it reduces the ability of the primary vector, the mosquito Aedes aegypti, to transmit viruses...
  80. Sakamoto H, Kageyama D, Hoshizaki S, Ishikawa Y. Heat treatment of the Adzuki bean borer, Ostrinia scapulalis infected with wolbachia gives rise to sexually mosaic offspring. J Insect Sci. 2008;8:1-5 pubmed publisher
    A maternally inherited intracellular bacterium, Wolbachia, causes reproductive alterations in its arthropod hosts...
  81. Watanabe M, Miura K, Hunter M, Wajnberg E. Superinfection of cytoplasmic incompatibility-inducing Wolbachia is not additive in Orius strigicollis (Hemiptera: Anthocoridae). Heredity (Edinb). 2011;106:642-8 pubmed publisher
    Cytoplasmic incompatibility (CI) allows the intracellular, maternally inherited bacterial symbiont Wolbachia to invade arthropod host populations by inducing infertility in crosses between infected males and uninfected females...
  82. Papafotiou G, Oehler S, Savakis C, Bourtzis K. Regulation of Wolbachia ankyrin domain encoding genes in Drosophila gonads. Res Microbiol. 2011;162:764-72 pubmed publisher
    The maternally inherited obligatory intracellular bacterium Wolbachia is a reproductive parasite of many insect species...
  83. Landmann F, Voronin D, Sullivan W, Taylor M. Anti-filarial activity of antibiotic therapy is due to extensive apoptosis after Wolbachia depletion from filarial nematodes. PLoS Pathog. 2011;7:e1002351 pubmed publisher
    Filarial nematodes maintain a mutualistic relationship with the endosymbiont Wolbachia. Depletion of Wolbachia produces profound defects in nematode development, fertility and viability and thus has great promise as a novel approach for ..
  84. Pan X, Zhou G, Wu J, Bian G, Lu P, Raikhel A, et al. Wolbachia induces reactive oxygen species (ROS)-dependent activation of the Toll pathway to control dengue virus in the mosquito Aedes aegypti. Proc Natl Acad Sci U S A. 2012;109:E23-31 pubmed publisher
    b>Wolbachia are maternally transmitted symbiotic bacteria that can spread within insect populations because of their unique ability to manipulate host reproduction...
  85. Zheng Y, Wang J, Liu C, Wang C, Walker T, Wang Y. Differentially expressed profiles in the larval testes of Wolbachia infected and uninfected Drosophila. BMC Genomics. 2011;12:595 pubmed publisher
    b>Wolbachia are endosymbiotic bacteria that are frequently found in arthropods and nematodes. These maternally inherited bacteria manipulate host reproduction by several mechanisms including cytoplasmic incompatibility (CI)...
  86. Verne S, Johnson M, Bouchon D, Grandjean F. Effects of parasitic sex-ratio distorters on host genetic structure in the Armadillidium vulgare-Wolbachia association. J Evol Biol. 2012;25:264-76 pubmed publisher
    In the pill bug Armadillidium vulgare (Crustacea, Oniscidea), Wolbachia facilitates its spread through vertical transmission via the eggs by inducing feminization of genetic males...
  87. Lee S, White V, Weeks A, Hoffmann A, Endersby N. High-throughput PCR assays to monitor Wolbachia infection in the dengue mosquito (Aedes aegypti) and Drosophila simulans. Appl Environ Microbiol. 2012;78:4740-3 pubmed publisher
    We have developed and validated two new fluorescence-based PCR assays to detect the Wolbachia wMel strain in Aedes aegypti and the wRi and wAu strains in Drosophila simulans...
  88. Duron O, Bernard J, Atyame C, Dumas E, Weill M. Rapid evolution of Wolbachia incompatibility types. Proc Biol Sci. 2012;279:4473-80 pubmed
    In most insects, the endosymbiont Wolbachia induces cytoplasmic incompatibility (CI), an embryonic mortality observed when infected males mate either with uninfected females or with females infected by an incompatible Wolbachia strain...
  89. Schuler H, Bertheau C, Egan S, Feder J, Riegler M, Schlick Steiner B, et al. Evidence for a recent horizontal transmission and spatial spread of Wolbachia from endemic Rhagoletis cerasi (Diptera: Tephritidae) to invasive Rhagoletis cingulata in Europe. Mol Ecol. 2013;22:4101-11 pubmed publisher
    The widespread occurrence of Wolbachia in arthropods and nematodes suggests that this intracellular, maternally inherited endosymbiont has the ability to cross species boundaries...
  90. Yamada R, Iturbe Ormaetxe I, Brownlie J, O Neill S. Functional test of the influence of Wolbachia genes on cytoplasmic incompatibility expression in Drosophila melanogaster. Insect Mol Biol. 2011;20:75-85 pubmed publisher
    b>Wolbachia are inherited intracellular bacteria that infect a broad range of invertebrate hosts. They commonly manipulate host reproduction in a variety of ways and thereby favour their invasion into host populations...
  91. Chafee M, Zecher C, Gourley M, Schmidt V, Chen J, Bordenstein S, et al. Decoupling of host-symbiont-phage coadaptations following transfer between insect species. Genetics. 2011;187:203-15 pubmed publisher
    ..Here we use the most common maternally transmitted bacteria, Wolbachia pipientis, to test the consequences of host genetic background on infection densities and the processes ..
  92. Kent B, Funkhouser L, Setia S, Bordenstein S. Evolutionary genomics of a temperate bacteriophage in an obligate intracellular bacteria (Wolbachia). PLoS ONE. 2011;6:e24984 pubmed publisher
    ..For example, the temperate double-stranded DNA bacteriophage WO in Wolbachia persistently transfers between bacterial coinfections in the same host...