vibrio cholerae o1

Summary

Summary: Strains of VIBRIO CHOLERAE containing O ANTIGENS group 1. All are CHOLERA-causing strains (serotypes). There are two biovars (biotypes): cholerae and eltor (El Tor).

Top Publications

  1. Mitra K, Ghosh A. Characterization of Vibrio cholerae O1 ElTor typing phage S5. Arch Virol. 2007;152:1775-86 pubmed
    S5 (ATCC No. 51352-B2), a Vibrio cholerae O1 ElTor typing phage was characterized. The growth characteristics and inactivation kinetics (thermal, UV and pH) of this lytic phage were investigated...
  2. Ghosh R, Nair G, Tang L, Morris J, Sharma N, Ballal M, et al. Epidemiological study of Vibrio cholerae using variable number of tandem repeats. FEMS Microbiol Lett. 2008;288:196-201 pubmed publisher
    ..Our data highlight the utility of the methodology as an epidemiologic tool for assessing spread of isolates in both epidemic and endemic settings. ..
  3. Saha D, LaRocque R, Khan A, Harris J, Begum Y, Akramuzzaman S, et al. Incomplete correlation of serum vibriocidal antibody titer with protection from Vibrio cholerae infection in urban Bangladesh. J Infect Dis. 2004;189:2318-22 pubmed
    ..No association between baseline vibriocidal titer and protection from V. cholerae O139 infection was found. Our findings suggest that the vibriocidal antibody is an incomplete predictor of protection from V. cholerae infection...
  4. Kumar P, Jain M, Goel A, Bhadauria S, Sharma S, Kamboj D, et al. A large cholera outbreak due to a new cholera toxin variant of the Vibrio cholerae O1 El Tor biotype in Orissa, Eastern India. J Med Microbiol. 2009;58:234-8 pubmed publisher
    ..cholerae O1 isolates. The results of this study suggest that cholera-causing V. cholerae strains are constantly evolving in epidemic areas, highlighting the potential of the emergence of more virulent strains. ..
  5. Gao Y, Pang B, Wang H, Zhou H, Cui Z, Kan B. Structural variation of the superintegron in the toxigenic Vibrio cholerae O1 El Tor. Biomed Environ Sci. 2011;24:579-92 pubmed publisher
    ..To understand the genetic structures and variations of the superintegron (SI) in Vibrio cholerae isolated in the seventh cholera pandemic...
  6. Ansaruzzaman M, Bhuiyan N, Safa A, Sultana M, McUamule A, Mondlane C, et al. Genetic diversity of El Tor strains of Vibrio cholerae O1 with hybrid traits isolated from Bangladesh and Mozambique. Int J Med Microbiol. 2007;297:443-9 pubmed
    b>Vibrio cholerae O1 strains that are hybrids between the classical and El Tor biotypes were isolated during two consecutive years (2004-2005) from diarrheal patients in Mozambique...
  7. Sharma N, Mandal P, Dhillon R, Jain M. Changing profile of Vibrio cholerae O1, O139 in Delhi & its periphery (2003-2005). Indian J Med Res. 2007;125:633-40 pubmed
    Cholera caused by either Vibrio cholerae O1 or O139 is endemic in Delhi and its peripheral areas. The present study was carried out to understand the changing epidemiology of V...
  8. Safa A, Bhuiyan N, Alam M, Sack D, Nair G. Genomic relatedness of the new Matlab variants of Vibrio cholerae O1 to the classical and El Tor biotypes as determined by pulsed-field gel electrophoresis. J Clin Microbiol. 2005;43:1401-4 pubmed
    The genomes of the recently described Matlab variants of Vibrio cholerae O1 that are hybrids between classical and El Tor biotypes were compared with those of El Tor and classical biotypes by the use of pulsed-field gel electrophoresis...
  9. Chatterjee S, Patra T, Ghosh K, Raychoudhuri A, Pazhani G, Das M, et al. Vibrio cholerae O1 clinical strains isolated in 1992 in Kolkata with progenitor traits of the 2004 Mozambique variant. J Med Microbiol. 2009;58:239-47 pubmed publisher

More Information

Publications98

  1. Naha A, Pazhani G, Ganguly M, Ghosh S, Ramamurthy T, Nandy R, et al. Development and evaluation of a PCR assay for tracking the emergence and dissemination of Haitian variant ctxB in Vibrio cholerae O1 strains isolated from Kolkata, India. J Clin Microbiol. 2012;50:1733-6 pubmed publisher
  2. Danin Poleg Y, Cohen L, Gancz H, Broza Y, Goldshmidt H, Malul E, et al. Vibrio cholerae strain typing and phylogeny study based on simple sequence repeats. J Clin Microbiol. 2007;45:736-46 pubmed
    ..Furthermore, discrimination between 27 strains of the 32 strains was achieved. SSR-based typing methods combining L-SSR and MNR-MLST were found to be efficient for V. cholerae typing...
  3. Mwansa J, Mwaba J, Lukwesa C, Bhuiyan N, Ansaruzzaman M, Ramamurthy T, et al. Multiply antibiotic-resistant Vibrio cholerae O1 biotype El Tor strains emerge during cholera outbreaks in Zambia. Epidemiol Infect. 2007;135:847-53 pubmed
    ..Since the emergence of antibiotic resistance may significantly influence strategies for controlling cholera, continuous monitoring of epidemic strains is crucial. ..
  4. Taviani E, Grim C, Choi J, Chun J, Haley B, Hasan N, et al. Discovery of novel Vibrio cholerae VSP-II genomic islands using comparative genomic analysis. FEMS Microbiol Lett. 2010;308:130-7 pubmed publisher
    ..cholerae. Interestingly, one of the new VSP-II revealed the presence of 'old' and 'new' V. cholerae O1 El Tor pandemic clones circulating in some of the areas where cholera is endemic...
  5. Islam M, Ahsan S, Khan S, Ahmed Q, Rashid M, Islam K, et al. Virulence properties of rough and smooth strains of Vibrio cholerae O1. Microbiol Immunol. 2004;48:229-35 pubmed
    ..A total of 10 strains including 5 each of rough and smooth strains of Vibrio cholerae O1 were tested and found positive for toxin production by enzyme-linked immunosorbent assay (ELISA) in ..
  6. Raychoudhuri A, Chatterjee S, Pazhani G, Nandy R, Bhattacharya M, Bhattacharya S, et al. Molecular characterization of recent Vibrio cholerae O1, El Tor, Inaba strains isolated from hospitalized patients in Kolkata, India. J Infect. 2007;55:431-8 pubmed
    ..This is not necessarily due to emergence of a new clone but does serve as an epidemiological marker. Further analysis at the molecular level will be required to define this trend and to monitor future spread to other regions. ..
  7. Grim C, Hasan N, Taviani E, Haley B, Chun J, Brettin T, et al. Genome sequence of hybrid Vibrio cholerae O1 MJ-1236, B-33, and CIRS101 and comparative genomics with V. cholerae. J Bacteriol. 2010;192:3524-33 pubmed publisher
    The genomes of Vibrio cholerae O1 Matlab variant MJ-1236, Mozambique O1 El Tor variant B33, and altered O1 El Tor CIRS101 were sequenced. All three strains were found to belong to the phylocore group 1 clade of V...
  8. Nusrin S, Khan G, Bhuiyan N, Ansaruzzaman M, Hossain M, Safa A, et al. Diverse CTX phages among toxigenic Vibrio cholerae O1 and O139 strains isolated between 1994 and 2002 in an area where cholera is endemic in Bangladesh. J Clin Microbiol. 2004;42:5854-6 pubmed publisher
    PCR surveillance of the rstR genes of CTX phages in Vibrio cholerae O1 and O139 showed no relationship between the incidence of disease and changes in the rstR but showed variations in their presence in O1 and O139 strains and the ..
  9. Sjölund Karlsson M, Reimer A, Folster J, Walker M, Dahourou G, Batra D, et al. Drug-resistance mechanisms in Vibrio cholerae O1 outbreak strain, Haiti, 2010. Emerg Infect Dis. 2011;17:2151-4 pubmed publisher
    ..cholerae outbreak strain. Most resistance resulted from acquired genes located on an integrating conjugative element showing high homology to an integrating conjugative element identified in a V. cholerae isolate from India. ..
  10. Shirin T, Rahman A, Danielsson A, Uddin T, Bhuyian T, Sheikh A, et al. Antimicrobial peptides in the duodenum at the acute and convalescent stages in patients with diarrhea due to Vibrio cholerae O1 or enterotoxigenic Escherichia coli infection. Microbes Infect. 2011;13:1111-20 pubmed publisher
    Patients with acute watery diarrhea caused by Vibrio cholerae O1 or enterotoxigenic Escherichia coli (ETEC) were analyzed for innate immune factors produced by the epithelium during the disease process...
  11. Mandomando I, Espasa M, Valles X, Sacarlal J, Sigauque B, Ruiz J, et al. Antimicrobial resistance of Vibrio cholerae O1 serotype Ogawa isolated in Manhiça District Hospital, southern Mozambique. J Antimicrob Chemother. 2007;60:662-4 pubmed
    To describe the antimicrobial susceptibility profile of isolated Vibrio cholerae O1 serotype Ogawa recovered from patients admitted to the cholera facility in the Manhiça District Hospital (MDH), Mozambique...
  12. Harris J, Cavallaro E, de Nóbrega A, Dos S Barrado J, Bopp C, Parsons M, et al. Field evaluation of crystal VC Rapid Dipstick test for cholera during a cholera outbreak in Guinea-Bissau. Trop Med Int Health. 2009;14:1117-21 pubmed publisher
    ..of use of the new commercially available Crystal VC Rapid Dipstick (VC) test (Span Diagnostics, India) for Vibrio cholerae O1 and O139...
  13. Lizárraga Partida M, Quilici M. Molecular analyses of Vibrio cholerae O1 clinical strains, including new nontoxigenic variants isolated in Mexico during the Cholera epidemic years between 1991 and 2000. J Clin Microbiol. 2009;47:1364-71 pubmed publisher
    We studied the evolution of Vibrio cholerae O1 during the 1991 to 2000 cholera epidemic in Mexico by biochemical, serological, and molecular characterization of strains collected during this period...
  14. Dutta B, Ghosh R, Sharma N, Pazhani G, Taneja N, Raychowdhuri A, et al. Spread of cholera with newer clones of Vibrio cholerae O1 El Tor, serotype inaba, in India. J Clin Microbiol. 2006;44:3391-3 pubmed
    During 2004 and 2005, cholera was recorded in 15 states of India, with 7 outbreaks. The newly emerged Vibrio cholerae O1 Inaba had a different antibiogram and ribotype, different pulsotypes, and different mutations in the wbeT gene...
  15. Scrascia M, Maimone F, Mohamud K, Materu S, Grimont F, Grimont P, et al. Clonal relationship among Vibrio cholerae O1 El Tor strains causing the largest cholera epidemic in Kenya in the late 1990s. J Clin Microbiol. 2006;44:3401-4 pubmed
    Eighty Vibrio cholerae O1 strains selected to represent the 1998-to-1999 history of the largest cholera epidemic in Kenya were characterized by ribotyping, antimicrobial susceptibility, and random amplified polymorphic DNA patterns...
  16. Okada K, Roobthaisong A, Nakagawa I, Hamada S, Chantaroj S. Genotypic and PFGE/MLVA analyses of Vibrio cholerae O1: geographical spread and temporal changes during the 2007-2010 cholera outbreaks in Thailand. PLoS ONE. 2012;7:e30863 pubmed publisher
    b>Vibrio cholerae O1 El Tor dominated the seventh cholera pandemic which occurred in the 1960s. For two decades, variants of V...
  17. Alam M, Sultana M, Nair G, Sack R, Sack D, Siddique A, et al. Toxigenic Vibrio cholerae in the aquatic environment of Mathbaria, Bangladesh. Appl Environ Microbiol. 2006;72:2849-55 pubmed
    ..The biofilm community is concluded to be an additional reservoir of cholera bacteria in the aquatic environment between seasonal epidemics of cholera in Bangladesh...
  18. Islam M, Jahid M, Rahman M, Rahman M, Islam M, Kabir M, et al. Biofilm acts as a microenvironment for plankton-associated Vibrio cholerae in the aquatic environment of Bangladesh. Microbiol Immunol. 2007;51:369-79 pubmed
    ..This study indicates that plexiglass can act as a bait to form biofilm, a microenvironment that provides shelter for plankton containing V. cholerae in the aquatic environment of Bangladesh...
  19. Na Ubol M, Srimanote P, Chongsa Nguan M, Indrawattana N, Sookrung N, Tapchaisri P, et al. Hybrid & El Tor variant biotypes of Vibrio cholerae O1 in Thailand. Indian J Med Res. 2011;133:387-94 pubmed
    El Tor Vibrio cholerae O1 carrying ctxB C trait, so-called El Tor variant that causes more severe symptoms than the prototype El Tor strain, first detected in Bangladesh was later shown to have emerged in India in 1992...
  20. Hartley D, Morris J, Smith D. Hyperinfectivity: a critical element in the ability of V. cholerae to cause epidemics?. PLoS Med. 2006;3:e7 pubmed
    ..Recent laboratory findings suggest that passage of Vibrio cholerae O1 Inaba El Tor through the gastrointestinal tract results in a short-lived, hyperinfectious state of the ..
  21. Das B, Halder K, Pal P, Bhadra R. Small chromosomal integration site of classical CTX prophage in Mozambique Vibrio cholerae O1 biotype El Tor strain. Arch Microbiol. 2007;188:677-83 pubmed
    An unusual strain of Vibrio cholerae O1 biotype El Tor harbouring multiple tandem copies of classical CTX prophage caused a cholera epidemic in Mozambique in 2004...
  22. Perez J, Acevedo R, Callicó A, Fernández Y, Cedré B, Año G, et al. A proteoliposome based formulation administered by the nasal route produces vibriocidal antibodies against El Tor Ogawa Vibrio cholerae O1 in BALB/c mice. Vaccine. 2009;27:205-12 pubmed publisher
    ..70+/-0.23) after two weeks from last dose. These results show for the first time that PL can be obtained from V. cholerae O1 and when administer by intranasal route has the potential to protect against this pathogen. ..
  23. Safa A, Nair G, Kong R. Evolution of new variants of Vibrio cholerae O1. Trends Microbiol. 2010;18:46-54 pubmed publisher
    ..Here, we describe recent advances in our understanding of the epidemiology and evolution of the atypical El Tor strains...
  24. Mukherjee P, Ghosh S, Ramamurthy T, Bhattacharya M, Nandy R, Takeda Y, et al. Evaluation of a rapid immunochromatographic dipstick kit for diagnosis of cholera emphasizes its outbreak utility. Jpn J Infect Dis. 2010;63:234-8 pubmed
    ..Furthermore, the use of a rapid detection test will improve surveillance and thus reduce the burden of disease estimates, especially in remote settings...
  25. Bari W, Song Y, Yoon S. Suppressed induction of proinflammatory cytokines by a unique metabolite produced by Vibrio cholerae O1 El Tor biotype in cultured host cells. Infect Immun. 2011;79:3149-58 pubmed publisher
    b>Vibrio cholerae O1 has two biotypes, El Tor and Classical, and the latter is now presumed to be extinct in nature...
  26. Chin C, Sorenson J, Harris J, Robins W, Charles R, Jean Charles R, et al. The origin of the Haitian cholera outbreak strain. N Engl J Med. 2011;364:33-42 pubmed publisher
    ..cholerae strain from a distant geographic source. (Funded by the National Institute of Allergy and Infectious Diseases and the Howard Hughes Medical Institute.). ..
  27. Akoachere J, Masalla T, Njom H. Multi-drug resistant toxigenic Vibrio cholerae O1 is persistent in water sources in New Bell-Douala, Cameroon. BMC Infect Dis. 2013;13:366 pubmed publisher
    ..pH and salinity significantly correlated with isolation of V. cholerae O1. Multidrug resistant Vibrio cholerae O1 with pathogenic potential is present in some wells and streams in study area...
  28. Taneja N, Biswal M, Tarai B, Sharma M. Emergence of Vibrio cholerae O1 Biotype El Tor serotype Inaba in north India. Jpn J Infect Dis. 2005;58:238-40 pubmed
    All cases of cholera that have occurred at our center in north India have been due to Vibrio cholerae O1 serotype Ogawa, including the outbreaks in 2002 and 2004. Here we report the emergence of V...
  29. Bhuiyan T, Lundin S, Khan A, Lundgren A, Harris J, Calderwood S, et al. Cholera caused by Vibrio cholerae O1 induces T-cell responses in the circulation. Infect Immun. 2009;77:1888-93 pubmed publisher
    ..We studied responses in adult patients hospitalized with cholera caused by Vibrio cholerae O1. Peripheral blood mononuclear cells from patients (n = 15) were analyzed by flow cytometry after stimulation ..
  30. Pugliese N, Maimone F, Scrascia M, Materu S, Pazzani C. SXT-related integrating conjugative element and IncC plasmids in Vibrio cholerae O1 strains in Eastern Africa. J Antimicrob Chemother. 2009;63:438-42 pubmed publisher
    ..The objective of this study was to investigate the extent of resistance patterns and associated mobile genetic elements in epidemic V. cholerae O1 El Tor strains isolated from Eastern Africa in the late 1990s...
  31. Lee J, Han K, Choi S, Lucas M, Mondlane C, Ansaruzzaman M, et al. Multilocus sequence typing (MLST) analysis of Vibrio cholerae O1 El Tor isolates from Mozambique that harbour the classical CTX prophage. J Med Microbiol. 2006;55:165-70 pubmed
    b>Vibrio cholerae O1 isolates belonging to the Ogawa serotype, El Tor biotype, harbouring the classical CTX prophage were first isolated in Mozambique in 2004...
  32. Mendes C, Abath F, Leal N. Development of a multiplex single-tube nested PCR (MSTNPCR) assay for Vibrio cholerae O1 detection. J Microbiol Methods. 2008;72:191-6 pubmed publisher
    A multiplex nested PCR method for detection of Vibrio cholerae O1 using a single tube was developed (MSTNPCR)...
  33. Stine O, Alam M, Tang L, Nair G, Siddique A, Faruque S, et al. Seasonal cholera from multiple small outbreaks, rural Bangladesh. Emerg Infect Dis. 2008;14:831-3 pubmed publisher
    ..The observed minimal overlap in VNTR patterns between the 2 communities was consistent with sequential, small outbreaks from local sources...
  34. Pal B, Khuntia H, Samal S, Das S, Chhotray G. Emergence of Vibrio cholerae O1 biotype El Tor serotype Inaba causing outbreaks of cholera in Orissa, India. Jpn J Infect Dis. 2006;59:266-9 pubmed
    ..Out of 265 culture-positive samples, Vibrio cholerae O1 was isolated in 56 samples (20.8%), of which 37 were the Inaba serotype and 19 were the Ogawa...
  35. Morin N, Gong Z, Li X. Reverse transcription-multiplex PCR assay for simultaneous detection of Escherichia coli O157:H7, Vibrio cholerae O1, and Salmonella Typhi. Clin Chem. 2004;50:2037-44 pubmed
    Escherichia coli O157:H7, Vibrio cholerae O1, and Salmonella Typhi are pathogenic bacteria that can be found in contaminated water supplies throughout the world...
  36. Johnson R, Uddin T, Aktar A, Mohasin M, Alam M, Chowdhury F, et al. Comparison of immune responses to the O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi adult patients with cholera. Clin Vaccine Immunol. 2012;19:1712-21 pubmed publisher
    Immunity against Vibrio cholerae O1 is serogroup specific, and serogrouping is defined by the O-specific polysaccharide (OSP) part of lipopolysaccharide (LPS). Despite this, human immune responses to V...
  37. Rashed S, Mannan S, Johura F, Islam M, Sadique A, Watanabe H, et al. Genetic characteristics of drug-resistant Vibrio cholerae O1 causing endemic cholera in Dhaka, 2006-2011. J Med Microbiol. 2012;61:1736-45 pubmed publisher
    b>Vibrio cholerae O1 biotype El Tor (ET), causing the seventh cholera pandemic, was recently replaced in Bangladesh by an altered ET possessing ctxB of the Classical (CL) biotype, which caused the first six cholera pandemics...
  38. Rivera I, Lipp E, Gil A, Choopun N, Huq A, Colwell R. Method of DNA extraction and application of multiplex polymerase chain reaction to detect toxigenic Vibrio cholerae O1 and O139 from aquatic ecosystems. Environ Microbiol. 2003;5:599-606 pubmed
    ..cholerae PCR, and O1/O139 serogroup and tcpA/ctxA genes by multiplex PCR offers an efficient system, permitting risk analysis for cholera in coastal areas...
  39. Beyhan S, Tischler A, Camilli A, Yildiz F. Differences in gene expression between the classical and El Tor biotypes of Vibrio cholerae O1. Infect Immun. 2006;74:3633-42 pubmed
    Differences in whole-genome expression patterns between the classical and El Tor biotypes of Vibrio cholerae O1 were determined under conditions that induce virulence gene expression in the classical biotype. A total of 524 genes (13...
  40. Kendall E, Chowdhury F, Begum Y, Khan A, Li S, Thierer J, et al. Relatedness of Vibrio cholerae O1/O139 isolates from patients and their household contacts, determined by multilocus variable-number tandem-repeat analysis. J Bacteriol. 2010;192:4367-76 pubmed publisher
    The genetic relatedness of Vibrio cholerae O1/O139 isolates obtained from 100 patients and 146 of their household contacts in Dhaka, Bangladesh, between 2002 and 2005 was assessed by multilocus variable-number tandem-repeat analysis...
  41. Tran H, Alam M, Trung N, Kinh N, Nguyen H, Pham V, et al. Multi-drug resistant Vibrio cholerae O1 variant El Tor isolated in northern Vietnam between 2007 and 2010. J Med Microbiol. 2012;61:431-7 pubmed publisher
    ..This study shows that multi-drug resistant V. cholerae altered El Tor producing classical CT strains are now predominant in northern Vietnam. ..
  42. Choi S, Lee J, Jeon Y, Lee H, Kim E, Ansaruzzaman M, et al. Multilocus variable-number tandem repeat analysis of Vibrio cholerae O1 El Tor strains harbouring classical toxin B. J Med Microbiol. 2010;59:763-9 pubmed publisher
    Atypical Vibrio cholerae O1 strains - hybrid strains (strains that cannot be classified either as El Tor or classical biotype) and altered strains (El Tor biotype strains that produce classical cholera toxin) - are currently prevalent in ..
  43. Frerichs R, Keim P, Barrais R, Piarroux R. Nepalese origin of cholera epidemic in Haiti. Clin Microbiol Infect. 2012;18:E158-63 pubmed publisher
    ..Such findings have important policy implications for shaping future international relief efforts...
  44. Safa A, Sultana J, Dac Cam P, Mwansa J, Kong R. Vibrio cholerae O1 hybrid El Tor strains, Asia and Africa. Emerg Infect Dis. 2008;14:987-8 pubmed publisher
  45. Seed K, Faruque S, Mekalanos J, Calderwood S, Qadri F, Camilli A. Phase variable O antigen biosynthetic genes control expression of the major protective antigen and bacteriophage receptor in Vibrio cholerae O1. PLoS Pathog. 2012;8:e1002917 pubmed publisher
  46. Ali M, Kim D, Yunus M, Emch M. Time series analysis of cholera in Matlab, Bangladesh, during 1988-2001. J Health Popul Nutr. 2013;31:11-9 pubmed
    ..Cholera cases were defined as Vibrio cholerae O1 isolated from faecal specimens of patients who sought care at treatment centres serving the Matlab ..
  47. Butler S, Nelson E, Chowdhury N, Faruque S, Calderwood S, Camilli A. Cholera stool bacteria repress chemotaxis to increase infectivity. Mol Microbiol. 2006;60:417-26 pubmed
    ..Through mutational analyses, such a state is known to enhance the infectivity of V. cholerae. This is the first report of a pathogen altering its chemotactic state in response to human infection in order to enhance its transmission...
  48. Bani S, Mastromarino P, Ceccarelli D, Le Van A, Salvia A, Ngo Viet Q, et al. Molecular characterization of ICEVchVie0 and its disappearance in Vibrio cholerae O1 strains isolated in 2003 in Vietnam. FEMS Microbiol Lett. 2007;266:42-8 pubmed
    We analyzed 28 epidemic Vibrio cholerae O1 strains isolated in the region of Thua Thien Hue (Vietnam) in 2003. Ubiquitous amoxicillin, prevalent aminoglycosides and sporadic erythromycin resistances were observed...
  49. Wang R, Lou J, Liu J, Zhang L, Li J, Kan B. Antibiotic resistance of Vibrio cholerae O1 El Tor strains from the seventh pandemic in China, 1961-2010. Int J Antimicrob Agents. 2012;40:361-4 pubmed publisher
    ..This study determined the regional resistance characteristics of epidemic clones in China and serves as a warning of the rapid dissemination of resistance in the past 20 years...
  50. Weil A, Arifuzzaman M, Bhuiyan T, LaRocque R, HARRIS A, Kendall E, et al. Memory T-cell responses to Vibrio cholerae O1 infection. Infect Immun. 2009;77:5090-6 pubmed publisher
    b>Vibrio cholerae O1 can cause diarrheal disease that may be life-threatening without treatment. Natural infection results in long-lasting protective immunity, but the role of T cells in this immune response has not been well characterized...
  51. Xicohtencatl Cortes J, Lyons S, Chaparro A, Hernández D, Saldaña Z, Ledesma M, et al. Identification of proinflammatory flagellin proteins in supernatants of Vibrio cholerae O1 by proteomics analysis. Mol Cell Proteomics. 2006;5:2374-83 pubmed
    ..This observation may explain, in part, the observed reactogenicity of cholera vaccine strains in humans...
  52. Kumar P, Wilson P, Bhai R, Thomas S. Characterization of an SXT variant Vibrio cholerae O1 Ogawa isolated from a patient in Trivandrum, India. FEMS Microbiol Lett. 2010;303:132-6 pubmed publisher
    ..In the present study, Vibrio cholerae O1 El Tor Ogawa isolated from a patient was examined for antibiotic susceptibility pattern, presence of SXT and ..
  53. O Shea Y, Finnan S, Reen F, Morrissey J, O Gara F, Boyd E. The Vibrio seventh pandemic island-II is a 26.9 kb genomic island present in Vibrio cholerae El Tor and O139 serogroup isolates that shows homology to a 43.4 kb genomic island in V. vulnificus. Microbiology. 2004;150:4053-63 pubmed
    ..vulnificus strain, CMCP6, did not contain the 43.4 kb VVI-I; in this strain two ORFs were found between the 5' and 3' flanking genes VV10636 and VV10632, showing 100 % identity to VV0508 and VV0561, respectively, which flank VVI-I...
  54. Fonseca E, Dos Santos Freitas F, Vieira V, Vicente A. New qnr gene cassettes associated with superintegron repeats in Vibrio cholerae O1. Emerg Infect Dis. 2008;14:1129-31 pubmed publisher
    A novel qnr determinant emerged in ciprofloxacin-resistant Vibrio cholerae O1 from the Amazon region of Brazil. This qnrVC1 was in a typical class 1 integron. Its attC showed 89% identity with V. parahaemolyticus superintegron repeats...
  55. Mohapatra S, Ramachandran D, Mantri C, Singh D. Characterization of the genetic background of Vibrio cholerae O1 biotype El Tor serotype Inaba strains isolated in Trivandrum, southern India. J Med Microbiol. 2007;56:260-5 pubmed
    Isolates of Vibrio cholerae O1 biotype El Tor serotype Inaba associated with an outbreak of cholera in Trivandrum, southern India, were characterized...
  56. Rawlings T, Ruiz G, Colwell R. Association of Vibrio cholerae O1 El Tor and O139 Bengal with the Copepods Acartia tonsa and Eurytemora affinis. Appl Environ Microbiol. 2007;73:7926-33 pubmed
    ..affinis. This difference in colonization may be significant in the general predominance of V. cholerae O1 in cholera epidemics in rural Bangladesh where water supplies are taken directly from the environment...
  57. Bröms J, Ishikawa T, Wai S, Sjostedt A. A functional VipA-VipB interaction is required for the type VI secretion system activity of Vibrio cholerae O1 strain A1552. BMC Microbiol. 2013;13:96 pubmed publisher
    ..In this study, mutagenesis of a defined region within the VipA protein was used to identify residues important for VipB binding in V. cholerae O1 strain A1552...
  58. Roychowdhury A, Pan A, Dutta D, Mukhopadhyay A, Ramamurthy T, Nandy R, et al. Emergence of tetracycline-resistant Vibrio cholerae O1 serotype Inaba, in Kolkata, India. Jpn J Infect Dis. 2008;61:128-9 pubmed
    ..3% for Ogawa and 15% for Inaba) was noted in 2005. It appears that the population might be at risk of infection by the Inaba serotype and that tetracycline may not be useful for the treatment...
  59. Roy S, Dutta B, Ghosh A, Sugunan A, Nandy R, Bhattacharya S, et al. Molecular tracking of the lineage of strains of Vibrio cholerae O1 biotype El Tor associated with a cholera outbreak in Andaman and Nicobar Islands, India. Trop Med Int Health. 2005;10:604-11 pubmed
    ..Twenty-one of the 67 stool samples from 67 patients were positive for toxigenic Vibrio cholerae O1, serotype Ogawa biotype El Tor, which showed striking similarity in its antibiogram with some of the strains ..
  60. Pal B, Khuntia H, Samal S, Kar S, Patnaik B. Epidemics of severe cholera caused by El Tor Vibrio cholerae O1 Ogawa possessing the ctxB gene of the classical biotype in Orissa, India. Int J Infect Dis. 2010;14:e384-9 pubmed publisher
    ..We investigated the epidemic of cholera that occurred in Kashipur and Dasmantpur blocks of Orissa, reported during July-September 2007...
  61. Bhunia R, Ramakrishnan R, Hutin Y, Gupte M. Cholera outbreak secondary to contaminated pipe water in an urban area, West Bengal, India, 2006. Indian J Gastroenterol. 2009;28:62-4 pubmed publisher
    ..Eight of the 12 water specimens from the affected area had fecal contamination and poor chlorine content. This outbreak was due to a contaminated municipal piped water supply and V. cholera 01 Inaba was possibly the causative organism...
  62. Scrascia M, Pugliese N, Maimone F, Mohamud K, Grimont P, Materu S, et al. Clonal relationship among Vibrio cholerae O1 El Tor strains isolated in Somalia. Int J Med Microbiol. 2009;299:203-7 pubmed publisher
    One hundred and three Vibrio cholerae O1 strains, selected to represent the cholera outbreaks which occurred in Somalia in 1998-1999, were characterized by random amplified polymorphic DNA patterns, ribotyping, and antimicrobial ..
  63. Patel S, Rahman M, Mohasin M, Riyadh M, Leung D, Alam M, et al. Memory B cell responses to Vibrio cholerae O1 lipopolysaccharide are associated with protection against infection from household contacts of patients with cholera in Bangladesh. Clin Vaccine Immunol. 2012;19:842-8 pubmed publisher
    b>Vibrio cholerae O1 causes cholera, a dehydrating diarrheal disease. We have previously shown that V...
  64. Matsuda F, Ishimura S, Wagatsuma Y, Higashi T, Hayashi T, Faruque A, et al. Prediction of epidemic cholera due to Vibrio cholerae O1 in children younger than 10 years using climate data in Bangladesh. Epidemiol Infect. 2008;136:73-9 pubmed
    ..over a 20-year period (1983-2002) comparing the number of children aged <10 years who were infected with Vibrio cholerae O1 to the maximum and minimum temperatures and rainfall...
  65. Goel A, Jain M, Kumar P, Sarguna P, Bai M, Ghosh N, et al. Molecular characterization reveals involvement of altered El Tor biotype Vibrio cholerae O1 strains in cholera outbreak at Hyderabad, India. J Microbiol. 2011;49:280-4 pubmed publisher
    ..The results of this study suggest that altered El Tor biotype V. cholerae with the classical cholera toxin gene are involved in cholera outbreaks in India...
  66. Nair G, Qadri F, Holmgren J, Svennerholm A, Safa A, Bhuiyan N, et al. Cholera due to altered El Tor strains of Vibrio cholerae O1 in Bangladesh. J Clin Microbiol. 2006;44:4211-3 pubmed
    We determined the types of cholera toxin (CT) produced by a collection of 185 Vibrio cholerae O1 strains isolated in Bangladesh over the past 45 years. All of the El Tor strains of V...
  67. Bishop A, Camilli A. Vibrio cholerae: lessons for mucosal vaccine design. Expert Rev Vaccines. 2011;10:79-94 pubmed publisher
    ..Further efforts are still required to provide more effective protection of young children...
  68. Ceccarelli D, Salvia A, Sami J, Cappuccinelli P, Colombo M. New cluster of plasmid-located class 1 integrons in Vibrio cholerae O1 and a dfrA15 cassette-containing integron in Vibrio parahaemolyticus isolated in Angola. Antimicrob Agents Chemother. 2006;50:2493-9 pubmed
    The resistance profile and its correlation with mobile genetic elements were investigated in 11 Vibrio cholerae O1 and 2 Vibrio parahaemolyticus clinical isolates, as well as in 1 V. cholerae O1 and 1 V...
  69. Opintan J, Newman M, Nsiah Poodoh O, Okeke I. Vibrio cholerae O1 from Accra, Ghana carrying a class 2 integron and the SXT element. J Antimicrob Chemother. 2008;62:929-33 pubmed publisher
    b>Vibrio cholerae O1 from a 2006 outbreak in Accra were commonly resistant to multiple antimicrobials and, in particular, to trimethoprim/sulfamethoxazole, drugs commonly used in the treatment of cholera...
  70. Chowdhury F, Khan A, Harris J, LaRocque R, Chowdhury M, Ryan E, et al. A comparison of clinical and immunologic features in children and older patients hospitalized with severe cholera in Bangladesh. Pediatr Infect Dis J. 2008;27:986-92 pubmed publisher
    ..Available vaccines provide less protection against cholera than natural infection, particularly in children...
  71. Wei Y, Ocampo P, Levin B. An experimental study of the population and evolutionary dynamics of Vibrio cholerae O1 and the bacteriophage JSF4. Proc Biol Sci. 2010;277:3247-54 pubmed publisher
    ..The results of this in vitro study make predictions that can be tested in natural populations of V. cholerae and cholera-infected patients...
  72. Morita M, Ohnishi M, Arakawa E, Yamamoto S, Nair G, Matsushita S, et al. Emergence and genetic diversity of El Tor Vibrio cholerae O1 that possess classical biotype ctxB among travel-associated cases of cholera in Japan. J Med Microbiol. 2010;59:708-12 pubmed publisher
    b>Vibrio cholerae O1 are classified into two biotypes, classical and El Tor, each encoding a biotype-specific cholera toxin. However, El Tor strains have recently emerged with a classical cholera-toxin genotype (El Tor variant)...
  73. Sarkar B, Ghosh A, Sen A, Rodrigues D. Newly isolated Vibrio cholerae non-O1, non-O139 phages. Emerg Infect Dis. 2004;10:754-6 pubmed
  74. Choi S, Lee J, Kim E, Lee H, Jeon Y, von Seidlein L, et al. Classical RS1 and environmental RS1 elements in Vibrio cholerae O1 El Tor strains harbouring a tandem repeat of CTX prophage: revisiting Mozambique in 2005. J Med Microbiol. 2010;59:302-8 pubmed publisher
    Currently, Vibrio cholerae O1 serogroup biotype El Tor strains producing classical type cholera toxin (altered strains or El Tor variants) are prevalent in Asia and in Mozambique...
  75. Tapchaisri P, Na Ubol M, Jaipaew J, Srimanote P, Chongsa Nguan M, Yamasaki S, et al. Virulence genes of clinical Vibrio cholerae O1 isolates in Thailand and their ribotypes. J Infect. 2007;55:557-65 pubmed
    ..To determine virulence associated-genes and ribotypes of Vibrio cholerae epidemic strains isolated from cholera patients in Thailand...
  76. Faruque A, Alam K, Malek M, Khan M, Ahmed S, Saha D, et al. Emergence of multidrug-resistant strain of Vibrio cholerae O1 in Bangladesh and reversal of their susceptibility to tetracycline after two years. J Health Popul Nutr. 2007;25:241-3 pubmed
  77. Tapchaisri P, Na Ubol M, Tiyasuttipan W, Chaiyaroj S, Yamasaki S, Wongsaroj T, et al. Molecular typing of Vibrio cholerae O1 isolates from Thailand by pulsed-field gel electrophoresis. J Health Popul Nutr. 2008;26:79-87 pubmed
    ..cholerae clinical isolates have public-health implications, not only for epidemic tracing of existing strains but also for the recognition of strains with new genotypes that may emerge in the future...
  78. Chatterjee S, Ghosh K, Raychoudhuri A, Pan A, Bhattacharya M, Mukhopadhyay A, et al. Phenotypic and genotypic traits and epidemiological implication of Vibrio cholerae O1 and O139 strains in India during 2003. J Med Microbiol. 2007;56:824-32 pubmed
    During 2003, Vibrio cholerae O1 Ogawa was the predominant serotype among diarrhoeal patients admitted to different hospitals in India...
  79. Kiiru J, Saidi S, Goddeeris B, Wamae N, Butaye P, Kariuki S. Molecular characterisation of Vibrio cholerae O1 strains carrying an SXT/R391-like element from cholera outbreaks in Kenya: 1994-2007. BMC Microbiol. 2009;9:275 pubmed publisher
    ..A total of 65 Vibrio cholerae O1 El Tor serotype Inaba isolated between 1994 and 2007 from various outbreaks in Kenya were investigated for ..
  80. Ang G, Yu C, Balqis K, Elina H, Azura H, Hani M, et al. Molecular evidence of cholera outbreak caused by a toxigenic Vibrio cholerae O1 El tor variant strain in Kelantan, Malaysia. J Clin Microbiol. 2010;48:3963-9 pubmed publisher
    ..cholerae O1 El Tor variant has invaded Malaysia, highlighting the need for continuous monitoring to facilitate early interventions against any potential epidemic by this biotype...
  81. Safa A, Bhuyian N, Nusrin S, Ansaruzzaman M, Alam M, Hamabata T, et al. Genetic characteristics of Matlab variants of Vibrio cholerae O1 that are hybrids between classical and El Tor biotypes. J Med Microbiol. 2006;55:1563-9 pubmed
    The Matlab variants of Vibrio cholerae O1, defined as hybrids between the classical and El Tor biotypes, were first isolated from hospitalized patients with acute secretory diarrhoea in Matlab, a rural area of Bangladesh...
  82. Scrascia M, Pugliese N, Maimone F, Mohamud K, Ali I, Grimont P, et al. Cholera in Ethiopia in the 1990 s: epidemiologic patterns, clonal analysis, and antimicrobial resistance. Int J Med Microbiol. 2009;299:367-72 pubmed publisher
    ..Cholera outbreaks persisted in Ethiopia with a recrudescence of cases in 1998. Twenty-two Vibrio cholerae O1 strains, selected to represent the 1998 history of cholera in Ethiopia, were characterized by random ..
  83. Faruque S, Tam V, Chowdhury N, Diraphat P, Dziejman M, Heidelberg J, et al. Genomic analysis of the Mozambique strain of Vibrio cholerae O1 reveals the origin of El Tor strains carrying classical CTX prophage. Proc Natl Acad Sci U S A. 2007;104:5151-6 pubmed
    Cholera outbreaks in subSaharan African countries are caused by strains of the El Tor biotype of toxigenic Vibrio cholerae O1. The El Tor biotype is the causative agent of the current seventh cholera pandemic, whereas the classical ..
  84. Son M, Megli C, Kovacikova G, Qadri F, Taylor R. Characterization of Vibrio cholerae O1 El Tor biotype variant clinical isolates from Bangladesh and Haiti, including a molecular genetic analysis of virulence genes. J Clin Microbiol. 2011;49:3739-49 pubmed publisher
    ..Notably, the sequencing of ctxB in some El Tor variants revealed two copies of classical ctxB, one per chromosome, contrary to previous reports that located ctxAB only on the large chromosome of El Tor biotype strains...
  85. Ceccarelli D, Spagnoletti M, Bacciu D, Cappuccinelli P, Colombo M. New V. cholerae atypical El Tor variant emerged during the 2006 epidemic outbreak in Angola. BMC Microbiol. 2011;11:130 pubmed publisher
    ..Virulence of V. cholerae relies on the powerful cholera toxin, encoded by the CTX prophage. The emergence of new pathogenic variants in the recent years has been mostly associated with new CTX prophage rearrangements...
  86. Kutar B, Rajpara N, Upadhyay H, Ramamurthy T, Bhardwaj A. Clinical isolates of Vibrio cholerae O1 El Tor Ogawa of 2009 from Kolkata, India: preponderance of SXT element and presence of Haitian ctxB variant. PLoS ONE. 2013;8:e56477 pubmed publisher
    ..was carried out to identify genetic factors responsible for multiple drug resistance in clinical isolates of Vibrio cholerae O1, serotype Ogawa, biotype El Tor isolated from the patients admitted to the Infectious Diseases Hospital, ..
  87. Ghosh Banerjee J, Senoh M, Takahashi T, Hamabata T, Barman S, Koley H, et al. Cholera toxin production by the El Tor variant of Vibrio cholerae O1 compared to prototype El Tor and classical biotypes. J Clin Microbiol. 2010;48:4283-6 pubmed publisher
    b>Vibrio cholerae O1 El Tor variant strains produced much more cholera toxin than did prototype El Tor strains...
  88. Patra T, Chatterjee S, Raychoudhuri A, Mukhopadhyay A, Ramamurthy T, Nandy R. Emergence and progression of Vibrio cholerae O1 El Tor variants and progenitor strains of Mozambique variants in Kolkata, India. Int J Med Microbiol. 2011;301:310-7 pubmed publisher
    Analysis of 75 Vibrio cholerae O1 strains isolated from hospitalized patients in Kolkata from 1989 to 1994 revealed the existence of true El Tor along with El Tor variants that possessed the classical allele of ctxB (ctxB(cl)) in strains ..
  89. Forssman B, Mannes T, Musto J, Gottlieb T, Robertson G, Natoli J, et al. Vibrio cholerae O1 El Tor cluster in Sydney linked to imported whitebait. Med J Aust. 2007;187:345-7 pubmed
    ..A review of importation practices of food from cholera-endemic regions may be required to prevent future transmission...