staphylococcus aureus

Summary

Summary: Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.

Webpages

  1. alanine and aspartate metabolism - toxoplasma gondii
    roos-compbio2.bio.upenn.edu/~fengchen/pathway/map00252.html
  2. pyrimidine metabolism - toxoplasma gondii
    roos-compbio2.bio.upenn.edu/~fengchen/pathway/map00240.html
  3. genome sequencing projects
    www.sanger.ac.uk/Projects/
  4. infectious diseases
    mansfield.osu.edu/~sabedon/biol4070.htm
  5. islander: database of genomic islands
    kementari.bioinformatics.vt.edu/cgi-bin/island.cgi?island=Mt ...
  6. diseases & conditions: information about diseases, viruses, conditions and prevention
    www.health.state.ny.us/diseases/
  7. islander: database of genomic islands
    kementari.bioinformatics.vt.edu/cgi-bin/bacteria.cgi?bacteri ...
  8. diseases & conditions: information about diseases, viruses, conditions and prevention
    www.health.state.ny.us/nysdoh/consumer/commun.htm
  9. islander: database of genomic islands
    kementari.bioinformatics.vt.edu/cgi-bin/bacteria.cgi?bacteri ...
  10. infectious disease core curriculum
    web.indstate.edu/thcme/micro/core.html

Research Grants

  1. Transmissible Spongiform Encephalopathies: Product Safet
    David M Asher; Fiscal Year: 2003
  2. Analysis of VraSR and VraSR regulated gene expression in Staphylococcus aureus
    Radheshyam K Jayaswal; Fiscal Year: 2008
  3. PENICILLIN INTERACTIVE PROTEINS OF STAPHYLOCOCCUS AUREUS
    Henry F Chambers; Fiscal Year: 2003
  4. Novel antibacterial agents for treatment of Tularemia
    Nachum Kaplan; Fiscal Year: 2004
  5. DnaK Protein Inhibitor Antimicrobials
    MICHAEL ALAN STURGESS; Fiscal Year: 2003
  6. Staphylococcal methicillin resistance locus
    Gordon L Archer; Fiscal Year: 2008
  7. Staphylococcal methicillin resistance locus
    Gordon L Archer; Fiscal Year: 2007
  8. Nanocarrier with metal bridge for affinity based delivery of metal binding peptid
    Elijah M Bolotin; Fiscal Year: 2008
  9. Proline uptake in staphylococcus aureus pathogenesis
    William R Schwan; Fiscal Year: 2002
  10. Single Cell Genomics of Human Microbial Flora
    ROGER LASKEN; Fiscal Year: 2008

Publications

  1. Clinical and microbiological aspects of linezolid resistance mediated by the cfr gene encoding a 23S rRNA methyltransferase
    Cesar A Arias
    Molecular Genetics and Antimicrobial Resistance Unit, Universidad El Bosque, Bogotá, Colombia
    J Clin Microbiol 46:892-6
  2. Three-year survey of community-acquired methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin in a French university hospital
    T Naas
    Service de Bactériologie virologie hygiène, Hôpital de Bicêtre, Assistance Publique, Hôpitaux de Paris, Faculté de Médecine Paris Sud, Le Kremlin Bicêtre, France
    J Hosp Infect 61:321-9
  3. Molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream isolates in urban Detroit
    Thea Chua
    Henry Ford Health System, Wayne State University School of Medicine, Detroit, Michigan 48202, USA
    J Clin Microbiol 46:2345-52
  4. Sporadic "transitional" community-associated methicillin-resistant Staphylococcus aureus strains from health care facilities in the United States
    Jennifer M Brady
    Molecular Microbiology Laboratory, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
    J Clin Microbiol 45:2654-61
  5. Virulence characteristics of community-associated Staphylococcus aureus and in vitro activities of moxifloxacin alone and in combination against community-associated and healthcare-associated meticillin-resistant and -susceptible S. aureus
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    J Med Microbiol 57:452-6
  6. Community- and health care-associated methicillin-resistant Staphylococcus aureus: a comparison of molecular epidemiology and antimicrobial activities of various agents
    Brian T Tsuji
    Anti Infective Research Laboratory, Department of Pharmacy Practice, Wayne State University, MI 48201, USA
    Diagn Microbiol Infect Dis 58:41-7
  7. Comparisons of community-associated methicillin-resistant Staphylococcus aureus (MRSA) and hospital-associated MSRA infections in Sacramento, California
    Hsin Huang
    Department of Infectious Disease, University of California, Davis, Medical Center, 4150 V Street, PSSB, G500, Sacramento, CA 95817, USA
    J Clin Microbiol 44:2423-7
  8. Resistance to methicillin and other antimicrobials among community-acquired and nosocomial Staphylococcus aureus strains in a pediatric teaching hospital in Salvador, Northeast Brazil
    Cristiana M Nascimento Carvalho
    Department of Pediatrics, School of Medicine, Federal University of Bahia UFBA, Salvador, Bahia, Brazil
    Microb Drug Resist 14:129-31
  9. Prevalence of inducible clindamycin resistance among community- and hospital-associated Staphylococcus aureus isolates
    Mukesh Patel
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
    J Clin Microbiol 44:2481-4
  10. Frequency of mecA gene and borderline oxacillin resistant Staphylococcus aureus in nosocomial acquired methicillin resistance Staphylococcus aureus infections
    F Khorvash
    Isfahan University of Medical Sciences, Hezar Jerib Street, Isfahan, Iran
    Pak J Biol Sci 11:1282-5

Scientific Experts

Detail Information

Webpages120 found, 30 most recent shown here

  1. alanine and aspartate metabolism - toxoplasma gondii
    roos-compbio2.bio.upenn.edu/~fengchen/pathway/map00252.html
  2. pyrimidine metabolism - toxoplasma gondii
    roos-compbio2.bio.upenn.edu/~fengchen/pathway/map00240.html
  3. genome sequencing projects
    www.sanger.ac.uk/Projects/
  4. infectious diseases
    mansfield.osu.edu/~sabedon/biol4070.htm
  5. islander: database of genomic islands
    kementari.bioinformatics.vt.edu/cgi-bin/island.cgi?island=Mt ...
  6. diseases & conditions: information about diseases, viruses, conditions and prevention
    www.health.state.ny.us/diseases/
  7. islander: database of genomic islands
    kementari.bioinformatics.vt.edu/cgi-bin/bacteria.cgi?bacteri ...
  8. diseases & conditions: information about diseases, viruses, conditions and prevention
    www.health.state.ny.us/nysdoh/consumer/commun.htm
  9. islander: database of genomic islands
    kementari.bioinformatics.vt.edu/cgi-bin/bacteria.cgi?bacteri ...
  10. infectious disease core curriculum
    web.indstate.edu/thcme/micro/core.html
  11. medical bacteria
    www.bact.wisc.edu/themicrobialworld/medical.html
  12. skin infection study guide
    www.cas.muohio.edu/~stevenjr/mbi111/skininf111.html#Gangrene
  13. bad bug book: introduction
    vm.cfsan.fda.gov/%7Emow/intro.html
  14. nitrogen metabolism - toxoplasma gondii
    roos-compbio2.bio.upenn.edu/~fengchen/pathway/map00910.html
  15. reportable diseases and conditions (florida) - privacy / data protection project (c)2002-2005
    privacy.med.miami.edu/glossary/xd_florida_rept_disease_condi ...
  16. bad bug book: introduction
    vm.cfsan.fda.gov/~mow/intro.html
  17. bacterial infections associated with hiv
    hivinsite.ucsf.edu/InSite?page=kb-00&doc=kb-05-01-01
  18. antimicrobial chemotherapy -agents that interfere with bacterial protein synthesis
    www.bmb.leeds.ac.uk/mbiology/ug/ugteach/icu8/antibiotics/pro ...
  19. staphylococcal infections- blue book: ideas - victorian government
    www.health.vic.gov.au/ideas/bluebook/staphylococcal.htm
  20. enterobacteriaceae : sites et documents francophones
    www.chu-rouen.fr/ssf/organ/enterobacteriaceae.html
  21. statewide program for infection control and epidemiology/guidelines
    www.unc.edu/depts/spice/new.html
  22. skin infection study guide
    www.cas.muohio.edu/~stevenjr/mbi111/skininf111.html#Candidia ...
  23. bsci 424 pathogenic microbiology -- staphylococcus
    www.life.umd.edu/classroom/bsci424/PathogenDescriptions/Stap ...
  24. infectious diseases - public health agency of canada
    www.phac-aspc.gc.ca/id-mi/index-eng.php
  25. staphylococcal infections (print version
    www.nlm.nih.gov/medlineplus/print/staphylococcalinfections.h ...
  26. cdc - increasing resistance to vancomycin and other glycopeptides in staphylococcus aureus
    www.cdc.gov/ncidod/eid/vol7no2/tenover.htm
  27. conjunctivitis in childhood
    www.utoronto.ca/kids/conjunct.htm
  28. channing laboratory - jean c. lee, phd
    www.channing.harvard.edu/lee_j.htm
  29. staphylococcal infections: medlineplus
    www.nlm.nih.gov/medlineplus/staphylococcalinfections.html
  30. bacterial infections associated with hiv
    hivinsite.ucsf.edu/InSite?page=kb-05-01-01#S9X

Research Grants62

  1. Transmissible Spongiform Encephalopathies: Product Safet
    David M Asher; Fiscal Year: 2003
    ..temperature, are most often skin bacteria: Gram-positive cocci--such as Staphylococcus epidermidis and Staphylococcus aureus--Bacillus cereus, and Gram-negative bacteria such as Enterobacter cloacae, Klebsiella spp and Serratia ..
  2. Analysis of VraSR and VraSR regulated gene expression in Staphylococcus aureus
    Radheshyam K Jayaswal; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Staphylococcus aureus is a prominent pathogen in today's society. It has been implicated in a number of potentially lethal diseases...
  3. PENICILLIN INTERACTIVE PROTEINS OF STAPHYLOCOCCUS AUREUS
    Henry F Chambers; Fiscal Year: 2003
    Methicillin-resistant strains of Staphylococcus aureus are a major clinical problem...
  4. Novel antibacterial agents for treatment of Tularemia
    Nachum Kaplan; Fiscal Year: 2004
    ..Lead compounds have shown good in vivo activity in treating Staphylococcus aureus infections in rats and have good oral bioavailability...
  5. DnaK Protein Inhibitor Antimicrobials
    MICHAEL ALAN STURGESS; Fiscal Year: 2003
    ..This lead compound cannot kill Staphylococcus aureus, Streptococcus pneumoniae, Helicobacter pylori or Haemophilus ducreyi, among other strains, in vitro...
  6. Staphylococcal methicillin resistance locus
    Gordon L Archer; Fiscal Year: 2008
    ..The First Specific Aim will be to investigate the transfer of SCCmec between strains of Staphylococcus aureus (SA) and from a different staphylococcal species, S. epidermidis (SE), to SA...
  7. Staphylococcal methicillin resistance locus
    Gordon L Archer; Fiscal Year: 2007
    ..The First Specific Aim will be to investigate the transfer of SCCmec between strains of Staphylococcus aureus (SA) and from a different staphylococcal species, S. epidermidis (SE), to SA...
  8. Nanocarrier with metal bridge for affinity based delivery of metal binding peptid
    Elijah M Bolotin; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Lysostaphin, a metalloendopeptidase that is bacteriolytic for Staphylococcus aureus, is a potential systemic therapy for treating multidrug-resistant S. aureus mediated infections...
  9. Proline uptake in staphylococcus aureus pathogenesis
    William R Schwan; Fiscal Year: 2002
    b>Staphylococcus aureus is a significant human pathogen, which is the leading cause of surgical-wound infections and the second most frequent cause of nosocomial bloodstream infections in the United States...
  10. Single Cell Genomics of Human Microbial Flora
    ROGER LASKEN; Fiscal Year: 2008
    ..Other pathogens to be studied will be Staphylococcus aureus, Streptococcus pneumoniae, and Pseudomonas aeruginosa from middle ear, and throat tissues and puss from ..
  11. Host Response in S. aureus Infections: Role of T cells
    Arthur O Tzianabos; Fiscal Year: 2006
    DESCRIPTION (provided by applicant): Staphylococcus aureus is an opportunistic bacterial pathogen responsible for a diverse spectrum of human and animal diseases, including wound infections, osteomyelitis, endocarditis, and bacteremia ..
  12. The Discovery of New Antibiotics from Deep Sea Actinomycete Bacteria
    William Fenical; Fiscal Year: 2008
    ..per year) against drug-resistant human pathogens of immediate concern, including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecalis (VREF), Pseudomonas aeruginosa, multi drug-resistant ..
  13. Horizontal Genetic Transfer In Straphylococi
    Ashley Robinson; Fiscal Year: 2008
    ..determinant and is thought to be horizontally transferred between the principal staphylococcal pathogen, Staphylococcus aureus, and commensal coagulase-negative species, such as S. epidermidis...
  14. Horizontal Genetic Transfer In Straphylococi
    Ashley Robinson; Fiscal Year: 2007
    ..determinant and is thought to be horizontally transferred between the principal staphylococcal pathogen, Staphylococcus aureus, and commensal coagulase-negative species, such as S. epidermidis...
  15. Syndecan and Bacterial Translocation in Shock and Trauma
    Carol L Wells; Fiscal Year: 2006
    ..faecalis and Staphylococcus aureus, but not gram-negative Salmonella typhimurium, Proteus mirabilis, and E. coli...
  16. Quorum sensing and Staphylococcus aureus pathogenesis
    Naomi Balaban; Fiscal Year: 2005
    ..Our aim is to better understand how virulence is regulated in Staphylococcus aureus and to further develop immunotherapy to staphylococcal infections. S...
  17. Host defense against Staphylococcus aureus skin infections
    Lloyd S Miller; Fiscal Year: 2008
    ..is to gain insight into mechanisms of cutaneous host defense against the common bacterial skin pathogen Staphylococcus aureus. S...
  18. A longitudinal Study of CA-MRSA Nasal Colonization in College Sports Participants
    Clarence Buddy Creech; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Staphylococcus aureus colonizes the anterior nares of nearly one-third of people and is the leading cause of skin and soft tissue infections in children and adults...
  19. PEGylated Lysostaphin for Staphylococcal Infections
    JOHN F KOKAI KUN; Fiscal Year: 2004
    ..Lysostaphin is a 27 kDa enzyme that cuts the pentaglycine cross-link in the cell wall peptidoglycan of Staphylococcus aureus. We have shown that lysostaphin is extremely effective in treating S...
  20. Bacterial Contaminants of Blood and Blood Products
    David M Asher; Fiscal Year: 2002
    ..temperature, are most often skin bacteria: Gram-positive cocci--such as Staphylococcus epidermidis and Staphylococcus aureus--Bacillus cereus, and Gram-negative bacteria such as Enterobacter cloacae, Klebsiella spp and Serratia ..
  21. Protein Structure/Function by NMR, Crystallography and Computational Chemistry
    Eric Oldfield; Fiscal Year: 2008
    ..to develop molecules that inhibit formation of the orange carotenoid virulence factor, staphyloxanthin, in Staphylococcus aureus. In recent work, we discovered that human squalene synthase inhibitors can also block staphyloxanthin ..
  22. Regulation of Virulence by luxS in Staphylococcus aureus
    MOHAMED OMAR ELASRI; Fiscal Year: 2005
    DESCRIPTION (provided by applicant): Staphylococcus aureus is an opportunistic pathogen that causes a wide range of diseases due to ability to produce a wide variety of virulence factors...
  23. Microbial Identification Using Surface Enhanced Laser De
    Patrick R Murray; Fiscal Year: 2003
    ..Identification of some common organisms (e.g., Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli) can be rapid (e.g...
  24. Applied Research on Antimicrobial Ressitance
    Daniel J Sexton; Fiscal Year: 2005
    ..cost of antimicrobial resistance for surgical site infections and bloodstream infections due to Staphylococcus aureus, so that investigators will be able to evaluate the cost effectiveness of proposed methods for the ..
  25. Photodynamic Therapy of Localized Infections
    Michael R Hamblin; Fiscal Year: 2008
    ..demonstrate that PDT will kill both Gram (-) species (eg Pseudomonas aeruginosa) and Gram (+) species (eg Staphylococcus aureus) in vivo in animal models of wounds, burns and deep established infections...
  26. DYNAMIC PLATELET - STAPHYLOCOCCAL INTERACTIONS
    Julia M Ross; Fiscal Year: 2004
    ..objective of the proposed research is to comprehensively characterize the molecular interactions between Staphylococcus aureus and platelets as a function of the dynamic shear environment in order to provide a rational basis for the ..
  27. Normal And Pathologic Mechanisms Of Inflammation, Innate
    Sharon M Wahl; Fiscal Year: 2006
    ..infectious pathogens, SLPI null and wildtype mice were infected with bacteria (Streptococcus pneumoniae, Staphylococcus aureus) or an intracellular parasite Leishmania major in a model of cutaneous leishmaniasis...
  28. Novel antibacterials targeting the 50S ribosomal subunit
    Joyce A Sutcliffe; Fiscal Year: 2005
    ..For use in nosocomial infections caused by Gram-positive pathogens, a drug must cover Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Enterococcus faecium...
  29. Selenium Coated Dialysis Catheters for Reduced Biofilm Formation
    Eric J Tobin; Fiscal Year: 2008
    ..I successfully demonstrated significant (>90%) reduction in biofilm formation for both gram positive (Staphylococcus aureus) and gram negative (Pseudomonas aeruginosa) bacteria on selenium coated polyurethane catheter material...
  30. 3rd ASM Conference on Cell-Cell Communication in Bacteria
    WILLIAM C FUQUA; Fiscal Year: 2007
    ..Well established systems such as the cyclic oligopeptide signals that regulate Staphylococcus aureus virulence and acyl homoserine lactones (AHLs) that control of pathogenesis in Pseudomonas aeruginosa are ..
  31. Outcomes of and Risk factors for Infections due to USA300 MRSA
    Kristen M Kreisel; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Staphylococcus aureus is an opportunistic bacterial pathogen causing substantial morbidity and mortality. Antibiotic resistance is common in S...
  32. MNEI/SerpinB1: A modulator of innate pulmonary defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2008
    ..aeruginosa, Haemophilus influenzae) and Gram-positive (Staphylococcus aureus) organisms and in two genetic backgrounds (C57BL/6 and129S6)...
  33. MNEI/SerpinB1: A modulator of innate pulmonary defense
    EILEEN REMOLD-O'DONNELL; Fiscal Year: 2007
    ..aeruginosa, Haemophilus influenzae) and Gram-positive (Staphylococcus aureus) organisms and in two genetic backgrounds (C57BL/6 and129S6)...
  34. Novel Biosensor for Detecting Antibiotic Resistance
    JEAN M CLARKE; Fiscal Year: 2006
    DESCRIPTION (provided by applicant): Antibacterial resistant Staphylococcus aureus, in particular methicillin-resistant S. aureus (MRSA), infections constitute a serious worldwide health problem...
  35. Strategies to Reduce Transmission of Antimicrobial Resis
    NAOMI P O'GRADY; Fiscal Year: 2006
    ..if rates of colonization and infection with 2 resistant Gram positive bacteria?methicillin resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococci (VRE)?among patients in adult intensive care units (ICUs) are ..
  36. Isolating novel actinomycetes for antibiotic discovery
    CHARLES MICHAEL MOORE; Fiscal Year: 2008
    ..as well as clinically important multi-drug-resistant bacterial pathogens including methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE), Acinetobacter baumannii, Enterobacteria expressing an ..
  37. Prenyldiphosphate Synthase Inhibitors: Novel Anti-Infective Agents
    Eric Oldfield; Fiscal Year: 2008
    ..coli and Staphylococcus aureus, as well as human FPPS (the target for the bisphosphonate drugs used in treating bone resorption diseases, ..
  38. Rapid sensitive low cost test for resistant microbes causing hospital infections
    SADANAND (Contact) GITE; Fiscal Year: 2008
    ..5B. About 20,000 of these fatalities are caused by methicillin-resistant Staphylococcus aureus bacteria (MRSA)...
  39. DRUG DESIGN FOR TREATING OPPORTUNISTIC INFECTION IN AIDS
    Kurt L Krause; Fiscal Year: 2003
    ..coli, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae have been used to produce purified protein...
  40. Generation of novel drugs against drug resistant bacteria through engineering of
    Ake P Elhammer; Fiscal Year: 2008
    ..suggest that the compound is well tolerated in mice and quite efficacious against systemic infections of Staphylococcus aureus, Streptococcus pyogenes and Streptococcus pneumoniae...
  41. Antibody- and peptide-inhibitors of quorum sensing
    Kim D Janda; Fiscal Year: 2004
    DESCRIPTION (provided by applicant): Staphylococcus aureus is a leading cause of diseases ranging from skin infections and food poisoning to life-threatening nosocomial infections. Increasing resistance of S...
  42. The Effect of Glucocorticoids in a Sedated and Ventilate
    Steven Solomon; Fiscal Year: 2006
    ..We have developed a sedated and ventilated model of canine Staphylococcus aureus bacterial pneumonia that simulates many of the pathophysiologic changes occurring during clinical sepsis...
  43. CONTROL OF ENTEROTOXIN GENE EXPRESSION IN S AUREUS
    George C Stewart; Fiscal Year: 2003
    Description (Adapted from applicant's abstract: Staphylococcus aureus is a major cause of human disease, especially nosocomial infections...
  44. Prenyldiphosphate Synthase Inhibitors: Novel Anti-Infective Agents
    Eric Oldfield; Fiscal Year: 2007
    ..coli and Staphylococcus aureus, as well as human FPPS (the target for the bisphosphonate drugs used in treating bone resorption diseases, ..
  45. Etiology, Epidemiology, and Clinical Outcomes of Health Care Associated Pneumonia
    Karl J Madaras-Kelly; Fiscal Year: 2008
    ..similar therapy (GTS)]; 2) identify risk factors for MDR bacteria including Methicillin-Resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, compared to non-MDR bacteria and develop models that accurately ..
  46. Statewide Implementation of Guidelines to Control MRSA
    Loreen A Herwaldt; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Methicillin (oxacillin)-resistant Staphylococcus aureus (MRSA) is by far the most common resistant bacterial pathogen...
  47. Statewide Implementation of Guidelines to Control MRSA
    Loreen A Herwaldt; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Methicillin (oxacillin)-resistant Staphylococcus aureus (MRSA) is by far the most common resistant bacterial pathogen...
  48. Novel Context-Activated Protide Anti-Infectives
    Michael R Yeaman; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Antibiotic-resistant strains of Staphylococcus aureus and Pseudomonas aeruginosa are among the most common causes of life-threatening infections in the world...
  49. Novel Context-Activated Protide Anti-Infectives
    Michael R Yeaman; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Antibiotic-resistant strains of Staphylococcus aureus and Pseudomonas aeruginosa are among the most common causes of life-threatening infections in the world...
  50. Mechanisms Involved in Flavin-linked Oxygen Metabolism
    H ALEXANDER CLAIBORNE; Fiscal Year: 2005
    ..coenzyme A-disulfide reductase (CoADR; NADPH + CoASSCoA to NADP+ + 2CoASH) from the serious human pathogen Staphylococcus aureus. CoADR nicely complements this emerging group of flavoproteins which utilize a single active-site Cys as ..
  51. The immunomodulatory role of bacterial proteins
    Triantafyllos Chavakis; Fiscal Year: 2006
    b>Staphylococcus aureus can cause superficial skin infections and, systemic infections that entail spread through the blood stream...
  52. Recombinant Listeria monocytogenes expressing ALS3: a vaccine against candidiasis
    Kevin W Bruhn; Fiscal Year: 2008
    ..Additionally, based on homology studies of Als tertiary structure to surface adhesins expressed on Staphylococcus aureus, we demonstrated that Als vaccination also improves survival in a murine model of disseminated ..
  53. High-Throughput Identification of RNA polymerase inhibitors in vivo
    Robert C Landick; Fiscal Year: 2006
    ..Methicillin-resistant Staphylococcus aureus (MRSA) is already spreading rapidly outside hospitals in the US and globally, and veterans of the Iraq war ..
  54. Development of MHC-Based Therapeutics for Superantigen-Induced Toxic Shock
    Roy A Mariuzza; Fiscal Year: 2008
    ..However, SEB is only one of 22 SAGs produced by Staphylococcus aureus and Streptococcus pyogenes, each capable of inducing toxic shock, some at far lower doses than SEB...
  55. Development of MHC-Based Therapeutics for Superantigen-Induced Toxic Shock
    Roy A Mariuzza; Fiscal Year: 2007
    ..However, SEB is only one of 22 SAGs produced by Staphylococcus aureus and Streptococcus pyogenes, each capable of inducing toxic shock, some at far lower doses than SEB...
  56. Structure, Function and Dynamics of Heme Degrading Enzymes
    Mario Rivera; Fiscal Year: 2006
    ..Moreover, it has been recently shown that during the early stages of infection Staphylococcus aureus prefers iron from heme...
  57. Structure, Function and Dynamics of Heme Degrading Enzymes
    Mario Rivera; Fiscal Year: 2007
    ..Moreover, it has been recently shown that during the early stages of infection Staphylococcus aureus prefers iron from heme...
  58. Structural Basis for Isoprenoid Biosynthesis
    Joseph P Noel; Fiscal Year: 2006
    ..Notably, this type 2 class of IPP isomerase is found in several Gram-positive bacteria such as Staphylococcus aureus suggesting that it will serve as an effective target for new anti-staphylococcal drugs...
  59. Structural Biology of Gram Positive Virulence Factors
    Cathleen A Earhart; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Gram-positive pathogens such as Staphylococcus aureus, Streptococcus pyogenes and Enterococcus faecalis are responsible for a number of deadly diseases. The ubiquitous S...
  60. Structural Biology of Gram Positive Virulence Factors
    Cathleen A Earhart; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Gram-positive pathogens such as Staphylococcus aureus, Streptococcus pyogenes and Enterococcus faecalis are responsible for a number of deadly diseases. The ubiquitous S...
  61. Development of B-Lock, an antibiofilm catheter lock product
    Krzysztof Appelt; Fiscal Year: 2008
    ..albicans and C. parapsilosis, methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococcus (VRE)...
  62. Toll Like Receptors on Conjunctival Epithelium
    Frank M Graziano; Fiscal Year: 2005
    ..suggest that conjunctival epithelial cells express a pattern recognition receptor, TLR2, and respond to Staphylococcus aureus peptidoglycan (SA-PGN) with mediator release and surface receptor upregulation...

Publications62

  1. Clinical and microbiological aspects of linezolid resistance mediated by the cfr gene encoding a 23S rRNA methyltransferase
    Cesar A Arias
    Molecular Genetics and Antimicrobial Resistance Unit, Universidad El Bosque, Bogotá, Colombia
    J Clin Microbiol 46:892-6
    ..was evaluated in the first cfr-carrying human hospital isolate of linezolid and methicillin-resistant Staphylococcus aureus (designated MRSA CM-05) by dilution and diffusion methods (including Etest)...
  2. Three-year survey of community-acquired methicillin-resistant Staphylococcus aureus producing Panton-Valentine leukocidin in a French university hospital
    T Naas
    Service de Bactériologie virologie hygiène, Hôpital de Bicêtre, Assistance Publique, Hôpitaux de Paris, Faculté de Médecine Paris Sud, Le Kremlin Bicêtre, France
    J Hosp Infect 61:321-9
    ..The incidence at Bicêtre Hospital was 0.8% of all S. aureus and 2% of all MRSA isolated. Our data indicate that these MRSA isolates might become hospital acquired...
  3. Molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream isolates in urban Detroit
    Thea Chua
    Henry Ford Health System, Wayne State University School of Medicine, Detroit, Michigan 48202, USA
    J Clin Microbiol 46:2345-52
    To gain a better understanding of epidemiology of resistance in Staphylococcus aureus, we describe the molecular epidemiology of methicillin-resistant Staphylococcus aureus bloodstream isolates in urban Detroit...
  4. Sporadic "transitional" community-associated methicillin-resistant Staphylococcus aureus strains from health care facilities in the United States
    Jennifer M Brady
    Molecular Microbiology Laboratory, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
    J Clin Microbiol 45:2654-61
    We describe phenotypic and genotypic traits of a group of methicillin-resistant Staphylococcus aureus (MRSA) clones that are either remnants of unsuccessful community-associated MRSA (CA-MRSA) clones or represent a transitional state ..
  5. Virulence characteristics of community-associated Staphylococcus aureus and in vitro activities of moxifloxacin alone and in combination against community-associated and healthcare-associated meticillin-resistant and -susceptible S. aureus
    Ellie J C Goldstein
    R M Alden Research Laboratory, Santa Monica, CA 90404, USA
    J Med Microbiol 57:452-6
    The increasing prevalence of community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA) poses a challenge for antimicrobial therapy of skin and soft tissue infections (SSTIs)...
  6. Community- and health care-associated methicillin-resistant Staphylococcus aureus: a comparison of molecular epidemiology and antimicrobial activities of various agents
    Brian T Tsuji
    Anti Infective Research Laboratory, Department of Pharmacy Practice, Wayne State University, MI 48201, USA
    Diagn Microbiol Infect Dis 58:41-7
    The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) is changing...
  7. Comparisons of community-associated methicillin-resistant Staphylococcus aureus (MRSA) and hospital-associated MSRA infections in Sacramento, California
    Hsin Huang
    Department of Infectious Disease, University of California, Davis, Medical Center, 4150 V Street, PSSB, G500, Sacramento, CA 95817, USA
    J Clin Microbiol 44:2423-7
    Methicillin-resistant Staphylococcus aureus (MRSA) has long been a common pathogen in healthcare facilities, but in the past decade, it has emerged as a problematic pathogen in the community setting as well...
  8. Resistance to methicillin and other antimicrobials among community-acquired and nosocomial Staphylococcus aureus strains in a pediatric teaching hospital in Salvador, Northeast Brazil
    Cristiana M Nascimento Carvalho
    Department of Pediatrics, School of Medicine, Federal University of Bahia UFBA, Salvador, Bahia, Brazil
    Microb Drug Resist 14:129-31
    To report the frequency of methicillin-resistant Staphylococcus aureus (MRSA) infection and to compare the antimicrobial resistance patterns between community-acquired (CA) and nosocomial (NI) strains stratified for resistance to ..
  9. Prevalence of inducible clindamycin resistance among community- and hospital-associated Staphylococcus aureus isolates
    Mukesh Patel
    Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, THT 229, 1530 3rd Avenue South, Birmingham, AL 35294 0006, USA
    J Clin Microbiol 44:2481-4
    Methicillin-resistant Staphylococcus aureus (MRSA) infections have become common among both hospitalized and nonhospitalized patients...
  10. Frequency of mecA gene and borderline oxacillin resistant Staphylococcus aureus in nosocomial acquired methicillin resistance Staphylococcus aureus infections
    F Khorvash
    Isfahan University of Medical Sciences, Hezar Jerib Street, Isfahan, Iran
    Pak J Biol Sci 11:1282-5
    ..Intrinsic high level resistance (mecA positive) and borderline oxacillin resistant Staphylococcus aureus (BORSA) were detected by amoxicillin-clavulanate E-test strips...
  11. Significance of fluoroquinolone-resistant Escherichia coli in urinary tract infections
    Katsumi Shigemura
    Department of Organ Therapeutics, Kobe University Graduate School of Medicine, Kobe 650 0017, Japan
    Jpn J Infect Dis 61:226-8
    ..Escherichia coli (FQRE), multidrug-resistant Pseudomonas aeruginosa (MDRP), and methicillin-resistant Staphylococcus aureus (MRSA)...
  12. Polyclonal emergence and importation of community-acquired methicillin-resistant Staphylococcus aureus strains harbouring Panton-Valentine leucocidin genes in Belgium
    O Denis
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium
    J Antimicrob Chemother 56:1103-6
    ..Worldwide spread of a limited number of Panton-Valentine leucocidin (PVL) -producing methicillin-resistant Staphylococcus aureus (MRSA) clones has been reported in various communities...
  13. Inducible clindamycin resistance and molecular epidemiologic trends of pediatric community-acquired methicillin-resistant Staphylococcus aureus in Dallas, Texas
    Susana Chavez Bueno
    University of Texas Southwestern Medical Center of Dallas, and Children s Medical Center of Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9063, USA
    Antimicrob Agents Chemother 49:2283-8
    Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection occurs commonly in children...
  14. Vancomycin susceptibility within methicillin-resistant Staphylococcus aureus lineages
    Robin A Howe
    Southmead Hospital, Bristol, United Kingdom
    Emerg Infect Dis 10:855-7
    Methicillin-resistant Staphylococcus aureus (MRSA) with reduced vancomycin susceptibility vancomycin-intermediate S. aureus (VISA) has been reported from many countries...
  15. Pseudomonas aeruginosa LasA protease in treatment of experimental staphylococcal keratitis
    Irina S Barequet
    Maurice and Gabriela Goldschleger Eye Research Institute, Sheba Medical Center, Tel Aviv University Sackler Faculty of Medicine, Tel-Hashomer 52621, Israel
    Antimicrob Agents Chemother 48:1681-7
    ..of LasA protease in the treatment of staphylococcal keratitis caused by methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA) isolates in a rabbit model...
  16. Update on emerging infections: news from the Centers for Disease Control and Prevention
    Gregory J Moran
    Department of Emergency Medicine, Olive View-UCLA Medical Center, Sylmar, CA, USA
    Ann Emerg Med 41:148-51
  17. Activities of clindamycin, daptomycin, doxycycline, linezolid, trimethoprim-sulfamethoxazole, and vancomycin against community-associated methicillin-resistant Staphylococcus aureus with inducible clindamycin resistance in murine thigh infection and in vi
    Kerry L LaPlante
    Anti Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, USA
    Antimicrob Agents Chemother 52:2156-62
    ..Controversy exists about the most effective treatment options for community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and about the ability of these strains to develop inducible resistance to clindamycin during ..
  18. Characterisation of non-multiresistant methicillin-resistant Staphylococcus aureus (including EMRSA-15) in Kuwait Hospitals
    E E Udo
    Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait
    Clin Microbiol Infect 12:262-9
    This study characterised non-multiresistant methicillin-resistant Staphylococcus aureus (nmMRSA) isolates from Kuwait hospitals to ascertain whether they were community-acquired MRSA (CA-MRSA)...
  19. Evolutionary relationships between sporadic and epidemic strains of healthcare-associated methicillin-resistant Staphylococcus aureus
    M Hallin
    Laboratoire de Référence MRSA Staphylocoques, Department of Microbiology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium
    Clin Microbiol Infect 14:659-69
    National surveillance of healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) isolates by pulsed-field gel electrophoresis (PFGE) typing allowed identification of rarely occurring 'sporadic' isolates with patterns ..
  20. Prevalence of SCCmec type IV in nosocomial bloodstream isolates of methicillin-resistant Staphylococcus aureus
    Priscila de A Trindade
    Department of Infectious Diseases, LIM 54, Hospital das Clinicas, University of Sao Paulo, Rua Harmonia 564/52, São Paulo-SP 05435000, Brazil
    J Clin Microbiol 43:3435-7
    Over a period of 7 months, 151 consecutive methicillin-resistant Staphylococcus aureus blood isolates were evaluated. None was community acquired...
  21. Characterization of methicillin resistant Staphylococcus aureus (MRSA) isolated at the Policlinico Hospital of Bari (Italy)
    Marialaura Corrente
    Department of Health and Animal Well-being, Faculty of Veterinary Medicine, University of Bari, Italy
    New Microbiol 28:57-65
    Methicillin resistant Staphylococcus aureus (MRSA) is an emerging problem. We studied 71 MRSA strains for the presence of mecA gene by PCR, for the enterotoxins production and susceptibility to antimicrobials...
  22. Susceptibilities to antiseptic agents and distribution of antiseptic-resistance genes qacA/B and smr of methicillin-resistant Staphylococcus aureus isolated in Asia during 1998 and 1999
    Norihisa Noguchi
    Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo 192 0392, Japan
    J Med Microbiol 54:557-65
    ..agents are used in hygienic handwashes in the prevention of nosocomial infections by methicillin-resistant Staphylococcus aureus (MRSA). The plasmid-borne genes qacA/B and smr confer resistance to cationic antiseptic agents in S...
  23. Pulse-field gel electrophoresis typing of methicillin-resistant Staphylococcus aureus strains susceptible to aminoglycosides isolated from 1993 to 2002
    M Lescat
    Laboratoire de Microbiologie, Hôpital Albert Chenevier, 40 rue de Mesly, 94000 Creteil, France
    J Hosp Infect 57:253-7
    Methicillin-resistant Staphylococcus aureus (MRSA) susceptible strains to aminoglycosides (AS-MRSA) have been increasingly isolated in the Albert Cheneiver Hospital during the past 10 years...
  24. Evolution, antimicrobial susceptibility and assignment to international clones of methicillin-resistant Staphylococcus aureus isolated over a 9-year period in two Spanish hospitals
    C Potel
    Hospital Xeral, Microbiology Laboratory, Vigo, Pontevedra, Spain
    Clin Microbiol Infect 13:728-30
    ..coagulase gene and repetitive element sequence-based PCR were used to classify 210 methicillin-resistant Staphylococcus aureus isolates recovered between 1997 and 2005 in two hospitals in Vigo, north-west Spain...
  25. Evolving problems with resistant pathogens
    J Chastre
    Université Paris 6 Pierre et Marie Curie, Service de Reanimation Medicale, Institut de Cardiologie, Hôpital Pitié Salpêtrière, AP HP, Paris, France
    Clin Microbiol Infect 14:3-14
    ..have changed dramatically, particularly because of the increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA), as well as the increasing rate of antimicrobial resistance seen in several species of Gram-..
  26. Changing pattern of antibiotic resistance in methicillin-resistant Staphylococcus aureus from German hospitals
    W Witte
    Robert Koch Institute, Wernigerode, Germany
    Infect Control Hosp Epidemiol 22:683-6
    OBJECTIVE: To investigate the background of changes of resistance phenotypes in methicillin-resistant Staphylococcus aureus (MRSA) from nosocomial infections in German hospitals by molecular typing and identification of particular ..
  27. Increasing prevalence of methicillin-resistant Staphylococcus aureus causing nosocomial infections at a university hospital in Taiwan from 1986 to 2001
    Po Ren Hsueh
    Department of Laboratory Medicine and Committee of Infection Control, National Taiwan University Hospital, Taipei, Taiwan
    Antimicrob Agents Chemother 48:1361-4
    A rapid emergence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection (from 26.3% in 1986 to 77% in 2001) was found...
  28. Susceptibility of Staphylococcus aureus to fusidic acid: Canadian data
    Robert P Rennie
    Medical Microbiology Laboratory, University of Alberta Hospital, Edmonton, Canada
    J Cutan Med Surg 10:277-80
    ..OBJECTIVE: To perform semiannual surveillance of fusidic acid susceptibility of Staphylococcus aureus strains in a Canadian tertiary care hospital. METHODS: S...
  29. Comparative pulsed-field gel electrophoresis typing of gentamicin-resistant and -susceptible methicillin-resistant Staphylococcus aureus strains isolated in France between 1991 and 1998. Changes in antibiotic susceptibility
    N Mangeney
    Laboratoire de Microbiologie, Hôpital Albert Chenevier, Créteil, France
    J Hosp Infect 51:262-8
    ..electrophoresis, we examined 504 non-redundant, infection-causing human isolates of methicillin-resistant Staphylococcus aureus susceptible (G(S): 238 isolates) or resistant to gentamicin (G(R): 266 isolates)...
  30. Risk factors and associated problems in the management of infections with methicillin resistant Staphylococcus aureus
    S Srinivasan
    Department of Clinical Microbiology, Pondicherry Institute of Medical Sciences, Pondicherry - 605 014, India
    Indian J Med Microbiol 24:182-5
    PURPOSE: It is necessary to define the problem of methicillin resistant Staphylococcus aureus (MRSA) in every hospital to evolve control strategies...
  31. Incidence of Staphylococcus aureus isolated from patients treated at the Clinical Center of Skopje, Macedonia, with special attention to MRSA
    Zaklina Cekovska
    Institute of Microbiology and Parasitology, Cyril and Methodius University, Skopje, Macedonia
    Acta Microbiol Immunol Hung 52:373-84
    The distribution of 3497 Staphylococcus aureus strains according to methicillin resistance, specimens, departmental profession and antibiotic resistance patterns was analysed...
  32. The emergence and importation of diverse genotypes of methicillin-resistant Staphylococcus aureus (MRSA) harboring the Panton-Valentine leukocidin gene (pvl) reveal that pvl is a poor marker for community-acquired MRSA strains in Ireland
    Angela S Rossney
    National MRSA Reference Laboratory, St James s Hospital, James s St, Dublin 8, Ireland
    J Clin Microbiol 45:2554-63
    Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) carrying pvl is an emerging problem worldwide...
  33. [Resistance to antibiotics of Staphylococcus aureus responsible of osteoarticular infections]
    J Raymond
    Université Renée Descartes, Service de Bactériologie, Hôpital Cochin, 27 r Fbg St Jacques 75014 Paris, France
    Arch Pediatr 14:S97-S101
    Osteo-articular infections represent the majority of invasive Staphylococcus aureus infections in children...
  34. An inhibitor of FtsZ with potent and selective anti-staphylococcal activity
    David J Haydon
    Prolysis, Begbroke Science Park, Oxfordshire OX5 1PF, UK
    Science 321:1673-5
    ..in vitro bactericidal activity against staphylococci, including methicillin- and multi-drug-resistant Staphylococcus aureus. The putative inhibitor-binding site of PC190723 was mapped to a region of FtsZ that is analogous to the ..
  35. Emergence of community-associated methicillin-resistant Staphylococcus aureus USA 300 clone as a cause of health care-associated infections among patients with prosthetic joint infections
    Ekaterina V Kourbatova
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
    Am J Infect Control 33:385-91
    BACKGROUND: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as an important cause of staphylococcal infections, but there have been little data on whether CA-MRSA causes health care-associated ..
  36. Comparison of community-acquired methicillin-resistant Staphylococcus aureus bacteremia to other staphylococcal species in a neonatal intensive care unit
    Jacob Kuint
    Neonatal Department, The Edmond and Lili Safra Children s Hospital, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Pediatr 166:319-25
    ..Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) was recently observed in our unit...
  37. Staphylococcal cassette chromosome mec and Panton-Valentine leukocidin characterization of methicillin-resistant Staphylococcus aureus clones
    Shannon M Moroney
    Esoteric Testing, Department of Pathology, Tampa General Hospital, P O Box 1289, Tampa, Florida 33601, USA
    J Clin Microbiol 45:1019-21
    ..leukocidin (PVL) gene carriage were compared among suspected community-associated methicillin-resistant Staphylococcus aureus MRSA (CA-MRSA) and health care-associated MRSA (HA-MRSA) isolates...
  38. Transmission and epidemiology of MRSA: current perspectives
    Maggi Banning
    The School of Health and Social Sciences, Middlesex University, Archway Campus, London
    Br J Nurs 14:548-51, 554
    b>Staphylococcus aureus is a gram-positive bacterium that developed resistance to the penicillin derivative methicillin. Subsequently, methicillin-resistant S...
  39. Antistaphylococcal activity of WCK 771, a tricyclic fluoroquinolone, in animal infection models
    Mahesh V Patel
    Wockhardt Research Centre, Aurangabad, India
    Antimicrob Agents Chemother 48:4754-61
    ..Only WCK 771 and clinafloxacin demonstrated strong potencies against vancomycin-intermediate Staphylococcus aureus strains (MICs = 1 microg/ml)...
  40. Community-acquired methicillin-resistant Staphylococcus aureus in children in northern Taiwan
    Yin-Hua Fang
    Department of Pediatrics, Min-Sheng General Hospital, Taoyuan, Taiwan, ROC
    J Microbiol Immunol Infect 37:29-34
    Methicillin-resistant Staphylococcus aureus (MRSA) infection is a well-recognized nosocomial infection of increasing incidence...
  41. Are community-associated methicillin-resistant Staphylococcus aureus (MRSA) strains replacing traditional nosocomial MRSA strains?
    Kyle J Popovich
    Division of Infectious Disease, Department of Medicine, Rush University Medical Center, and Division of Infectious Disease, Department of Medicine, Stroger Hospital of Cook County, Chicago, Illinois 60612, USA
    Clin Infect Dis 46:787-94
    BACKGROUND: Recent studies have suggested that community-associated methicillin-resistant Staphylococcus aureus (MRSA) infection is encroaching on health care settings...
  42. Molecular epidemiology of community- and health care-associated methicillin-resistant Staphylococcus aureus in Manitoba, Canada
    John L Wylie
    Cadham Provincial Public Health Laboratory, Manitoba Health, P O Box 8450, 750 William Ave, Winnipeg, Manitoba, R3C 3Y1
    J Clin Microbiol 43:2830-6
    Recently, acquisition of methicillin-resistant Staphylococcus aureus (MRSA) has been increasingly seen in community settings...
  43. Hospital transmission of community-acquired methicillin-resistant Staphylococcus aureus among postpartum women
    Lisa Saiman
    Department of Pediatrics, Columbia University, New York, New York 10032, USA
    Clin Infect Dis 37:1313-9
    Infections caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are being increasingly observed in patients who lack traditional risk factors...
  44. Methicillin-resistant versus methicillin-sensitive Staphylococcus aureus infective endocarditis
    E E Hill
    Department of Internal Medicine Infectious Diseases, K U Leuven, University Hospital Gasthuisberg, Leuven, Belgium
    Eur J Clin Microbiol Infect Dis 27:445-50
    The incidence of methicillin-resistant Staphylococcus aureus (MRSA) infective endocarditis (IE) is increasing. This study compared clinical characteristics and mortality in patients with methicillin-sensitive S...
  45. Spread of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) in hospitals in Taipei, Taiwan in 2005, and comparison of its drug resistance with previous hospital-acquired MRSA
    Tomomi Takano
    Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Japan, and National Taiwan University Hospital, Taipei, Taiwan
    Microbiol Immunol 51:627-32
    Panton-Valentine leucocidin (PVL)-positive methicillin-resistant Staphylococcus aureus (PVL+ MRSA) is an emerging pathogen in the community worldwide. The incidence of PVL+ MRSA in Taipei, Taiwan was 23.3% for hospital MRSA...
  46. Comparison of genetic backgrounds of methicillin-resistant and -susceptible Staphylococcus aureus isolates from Portuguese hospitals and the community
    M Aires de Sousa
    Laboratório de Genética Molecular, Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Oeiras, Portugal
    J Clin Microbiol 43:5150-7
    In order to understand the origins of the dominant methicillin-resistant Staphylococcus aureus (MRSA) clones in Portuguese hospitals, we compared the genetic backgrounds of nosocomial MRSA with methicillin-susceptible S...
  47. Antimicrobial susceptibility and clonal relatedness between community- and hospital-acquired methicillin-resistant Staphylococcus aureus from blood cultures
    Sook In Jung
    Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Republic of Korea
    J Microbiol 44:336-43
    ..clonal relationships among the community-acquired (CA) and hospital-acquired (HA) methicillin-resistant Staphylococcus aureus (MRSA) strains that were isolated from blood cultures in a university hospital over a 4-year period...
  48. Staphylococcus aureus strains isolated from bloodstream infections changed significantly in 2006
    Nathalie van der Mee Marquet
    EA 3854, IFR 136, UFR Médecine Université François Rabelais, 2 bis boulevard Tonnelé, 37032 Tours Cedex, France
    J Clin Microbiol 45:851-7
    We studied 358 Staphylococcus aureus strains isolated from bloodstream infections (BSI) observed during an epidemiological study covering 2,007,681 days of hospitalization in 32 healthcare institutions (HCIs) between 2004 and 2006...
  49. Epidemiology and typing of Staphylococcus aureus strains isolated from bloodstream infections
    Nathalie van der Mee Marquet
    Departement de Microbiologie et Moléculaire, UFR Médecine, Tours Cedex, France
    J Clin Microbiol 42:5650-7
    ..During this time, 413 Staphylococcus aureus bloodstream infections occurred...
  50. In vitro activity of daptomycin against multidrug-resistant Staphylococcus aureus and S. aureus with known virulence factors, including community-acquired methicillin-resistant isolates
    Diane M Anastasiou
    Cubist Pharmaceuticals Inc, Lexington, MA 02421, USA
    Diagn Microbiol Infect Dis 61:339-42
    The in vitro activity of daptomycin was evaluated against 360 multidrug-resistant Staphylococcus aureus isolates (including hospital-acquired isolates) and multidrug-susceptible community-acquired methicillin-resistant S...
  51. Bactericidal activity of orally available agents against methicillin-resistant Staphylococcus aureus
    Anjum S Kaka
    Section of Infectious Diseases, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX 77030, USA
    J Antimicrob Chemother 58:680-3
    BACKGROUND: The recent proliferation of community-acquired (CA) methicillin-resistant Staphylococcus aureus (MRSA) has led to a marked increase in the need for outpatient treatment of MRSA infections...
  52. Mupirocin resistance in Staphylococcus aureus in an Indian hospital
    Ravisekhar Gadepalli
    Department of Microbiology, All India Institute of Medical Sciences, New Delhi 29, India
    Diagn Microbiol Infect Dis 58:125-7
    Two hundred Staphylococcus aureus strains collected from an Indian hospital were tested for mupirocin susceptibility using disc diffusion method and E-test...
  53. [Methicillin-resistant Staphylococcus aureus (MRSA) in the community]
    A G Vonk
    VU Medisch Centrum, afd Medische Microbiologie en Infectiepreventie, Postbus 7057, 1007 MB, Amsterdam
    Ned Tijdschr Geneeskd 151:401-7
    Methicillin-resistant Staphylococcus aureus (MRSA) infections have been confined to healthcare centres for decades. However, MRSA infections are increasingly seen in young healthy individuals with no exposure to healthcare centres...
  54. A useful clinical approach to community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections
    B A Cunha
    J Hosp Infect 68:271-3
  55. Antimicrobial susceptibility and staphylococcal chromosomal cassette mec type in community- and hospital-associated methicillin-resistant Staphylococcus aureus
    Kerry L LaPlante
    Anti Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48201, USA
    Pharmacotherapy 27:3-10
    STUDY OBJECTIVE: To differentiate the characteristics of community-associated methicillin-resistant Staphylococcus aureus (MRSA) and hospital-associated MRSA isolates on the basis of their susceptibility profiles, induction of ..
  56. [Stakes, treatment strategies and progression of MRSA nosocomial pneumonia, especially pneumonia due to mechanical ventilation]
    R G Wunderink
    Methodist Healthcare, University of Tennessee, Memphis, USA
    Presse Med 33:2S5-9
    ..BETWEEN EFFICACY AND TOLERANCE: The increase in the MIC of vancomycin in the serum and the lungs during acute MRSA acquired under mechanical ventilation may provoke problems in tolerance, notably renal...
  57. Vancomycin intermediate and resistant Staphylococcus aureus. What the nephrologist needs to know
    L Clifford McDonald
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Nephrol News Issues 18:63-4, 66-7, 71-2 passim
    ..hemodialysis may be at increased risk for emerging antimicrobial resistance from vancomycin-intermediate Staphylococcus aureus (VISA) and vancomycin-resistant S. aureus (VRSA)...
  58. Comparative in vitro activity of quinupristin/dalfopristin and seven other antimicrobials against methicillin-susceptible and methicillin-resistant nosocomial Staphylococcus aureus bloodstream isolates
    P Nikolaidis
    First Department of Internal Medicine, Infectious Diseases Division, University Hospital AHEPA, Thessaloniki, Greece
    J Chemother 14:544-6
    b>Staphylococcus aureus strains resistant to a variety of antimicrobial agents are often found in the hospital environment and are responsible for many life-threatening infections...
  59. Staphylococcus aureus nasal carriage in the community: a survey from central Italy
    G Zanelli
    Clinica delle Malattie Infettive, Dipartimento di Biologia Molecolare, Università di Siena, Italia
    Epidemiol Infect 129:417-20
    Recently, concern has increased regarding the spread of methicillin-resistant Staphylococcus aureus (MRSA) in the community. We studied 812 subjects from central Italy to establish the rates of nasal carriage of S...
  60. [Nosocomial methicillin-resistant staphylococci that remain sensitive to non-beta lactam antibiotics]
    Roberto Manfredi
    Recenti Prog Med 94:344