haemophilus parasuis

Summary

Summary: A species of gram-negative bacteria in the genus HAEMOPHILUS found, in the normal upper respiratory tract of SWINE.

Top Publications

  1. Melnikow E, Dornan S, Sargent C, Duszenko M, Evans G, Gunkel N, et al. Microarray analysis of Haemophilus parasuis gene expression under in vitro growth conditions mimicking the in vivo environment. Vet Microbiol. 2005;110:255-63 pubmed
    b>Haemophilus parasuis is the causative agent of polyserositis in pigs, a mostly fatal disease on the rise especially in early-weaned pigs and in pig herds with a high-health status. The mechanisms by which H...
  2. Martinez Moliner V, Soler Llorens P, Moleres J, Garmendia J, Aragon V. Distribution of genes involved in sialic acid utilization in strains of Haemophilus parasuis. Microbiology. 2012;158:2117-24 pubmed publisher
    b>Haemophilus parasuis is a porcine respiratory pathogen, well known as the aetiological agent of Glässer's disease. H. parasuis comprises strains of different virulence, but the virulence factors of this bacterium are not well defined...
  3. Mullins M, Register K, Bayles D, Butler J. Haemophilus parasuis exhibits IgA protease activity but lacks homologs of the IgA protease genes of Haemophilus influenzae. Vet Microbiol. 2011;153:407-12 pubmed publisher
    b>Haemophilus parasuis, the bacterium responsible for Glässer's disease, is a pathogen of significant concern in modern high-health swine production systems but there is little information regarding the identity or function of its ..
  4. Zehr E, Tabatabai L. Detection of a bacteriophage gene encoding a Mu-like portal protein in Haemophilus parasuis reference strains and field isolates by nested polymerase chain reaction. J Vet Diagn Invest. 2011;23:538-42 pubmed publisher
    ..encoding a bacteriophage Mu-like portal protein, gp29, in 15 reference strains and 31 field isolates of Haemophilus parasuis. Specific primers, based on the gene's sequence, were utilized...
  5. Wang Y, Liu C, Fang Y, Liu X, Li W, Liu S, et al. Transcription analysis on response of porcine alveolar macrophages to Haemophilus parasuis. BMC Genomics. 2012;13:68 pubmed publisher
    b>Haemophilus parasuis (H. parasuis) is the etiological agent of Glässer's disease in pigs. Currently, the molecular basis of this infection is largely unknown...
  6. Tian H, Fu F, Li X, Chen X, Wang W, Lang Y, et al. Identification of the immunogenic outer membrane protein A antigen of Haemophilus parasuis by a proteomics approach and passive immunization with monoclonal antibodies in mice. Clin Vaccine Immunol. 2011;18:1695-701 pubmed publisher
    Monoclonal antibodies (MAbs) against Haemophilus parasuis were generated by fusing spleen cells from BALB/c mice immunized with whole bacterial cells with SP2/0 murine myeloma cells...
  7. Del Rio M, Martín C, Navas J, Gutiérrez Muñiz B, Rodriguez Barbosa J, Rodriguez Ferri E. aroA gene PCR-RFLP diversity patterns in Haemophilus parasuis and Actinobacillus species. Res Vet Sci. 2006;80:55-61 pubmed
    The Haemophilus parasuis aroA gene encodes 5-enolpyruvylshikimate-3-phosphate synthase and participates in the aromatic amino acids and the folic acid universal metabolic pathway of bacteria...
  8. Liu X, Chen H, Tong Q, Li X, Zhu M, Wu Z, et al. Molecular characterization of caveolin-1 in pigs infected with Haemophilus parasuis. J Immunol. 2011;186:3031-46 pubmed publisher
    ..in pigs following stimulation with LPS/polyinosinic-polycytidylic acid as well as during infection with Haemophilus parasuis. The porcine Cav1 gene is 35 kb long and is located at SSC18q21; two isoforms (Cav1-? and Cav1-?) are ..
  9. Martín de la Fuente A, Rodriguez Ferri E, Frandoloso R, Martinez S, Tejerina F, Gutiérrez Martín C. Systemic antibody response in colostrum-deprived pigs experimentally infected with Haemophilus parasuis. Res Vet Sci. 2009;86:248-53 pubmed publisher
    The serum antibody response to an experimental infection by Haemophilus parasuis, the etiological agent of Glässer's disease in pigs, was characterized by ELISA measuring IgM and IgGt levels against whole-cells and outer-membrane-..

More Information

Publications81

  1. Olvera A, Cerdà Cuéllar M, Aragon V. Study of the population structure of Haemophilus parasuis by multilocus sequence typing. Microbiology. 2006;152:3683-90 pubmed
    b>Haemophilus parasuis is the aetiological agent of Glässer's disease in swine. In addition, this bacterium causes other clinical outcomes and can also be isolated from the upper respiratory tract of healthy pigs. Isolates of H...
  2. Castilla K, de Gobbi D, Moreno L, Paixão R, Coutinho T, Dos Santos J, et al. Characterization of Haemophilus parasuis isolated from Brazilian swine through serotyping, AFLP and PFGE. Res Vet Sci. 2012;92:366-71 pubmed publisher
    b>Haemophilus parasuis infection in pigs is characterized by fibrinous polyserositis, arthritis and meningitis...
  3. Costa Hurtado M, Ballester M, Galofre Mila N, Darji A, Aragon V. VtaA8 and VtaA9 from Haemophilus parasuis delay phagocytosis by alveolar macrophages. Vet Res. 2012;43:57 pubmed publisher
    b>Haemophilus parasuis, a member of the family Pasteurellaceae, is a common inhabitant of the upper respiratory tract of healthy pigs and the etiological agent of Glässer's disease. As other virulent Pasteurellaceae, H...
  4. Li J, Jiang P, Wang Y, Li Y, Chen W, Wang X, et al. Genotyping of Haemophilus parasuis from diseased pigs in China and prevalence of two coexisting virus pathogens. Prev Vet Med. 2009;91:274-9 pubmed publisher
    From December 2003 to July 2006, a total of 131 (28.4%) Haemophilus parasuis strains were isolated from 462 cases examined in our diagnostic laboratory...
  5. Costa Hurtado M, Aragon V. Advances in the quest for virulence factors of Haemophilus parasuis. Vet J. 2013;198:571-6 pubmed publisher
    b>Haemophilus parasuis colonises healthy pigs and is the aetiological agent of Glässer's disease. The pathogenicity of H. parasuis is poorly characterised, while prevention and control of Glässer's disease continues to be challenging...
  6. Howell K, Weinert L, Luan S, Peters S, Chaudhuri R, Harris D, et al. Gene content and diversity of the loci encoding biosynthesis of capsular polysaccharides of the 15 serovar reference strains of Haemophilus parasuis. J Bacteriol. 2013;195:4264-73 pubmed publisher
    b>Haemophilus parasuis is the causative agent of Glässer's disease, a systemic disease of pigs, and is also associated with pneumonia. H. parasuis can be classified into 15 different serovars...
  7. Brockmeier S. Prior infection with Bordetella bronchiseptica increases nasal colonization by Haemophilus parasuis in swine. Vet Microbiol. 2004;99:75-8 pubmed
    ..study was to determine whether Bordetella bronchiseptica would predispose to colonization or disease with Haemophilus parasuis. Three experiments were completed...
  8. Pina S, Olvera A, Barceló A, Bensaid A. Trimeric autotransporters of Haemophilus parasuis: generation of an extensive passenger domain repertoire specific for pathogenic strains. J Bacteriol. 2009;191:576-87 pubmed publisher
    b>Haemophilus parasuis is the agent responsible for causing Glässer's disease, but little is known about the pathogenic determinants of this major pig disease...
  9. Olvera A, Segales J, Aragon V. Update on the diagnosis of Haemophilus parasuis infection in pigs and novel genotyping methods. Vet J. 2007;174:522-9 pubmed
    b>Haemophilus parasuis causes Glässer's disease as well as a number of other diseases in pigs. The diagnosis of H...
  10. Olvera A, Pina S, Pérez Simó M, Oliveira S, Bensaid A. Virulence-associated trimeric autotransporters of Haemophilus parasuis are antigenic proteins expressed in vivo. Vet Res. 2010;41:26 pubmed publisher
    ..Members of this family have been described in Haemophilus parasuis and designated as virulence-associated trimeric autotransporters (VtaA)...
  11. Jabłoński A, Zebek S, Kołacz R, Pejsak Z. Usefulness of PCR/RFLP and ERIC PCR techniques for epidemiological study of Haemophilus parasuis infections in pigs. Pol J Vet Sci. 2011;14:111-6 pubmed
    b>Haemophilus parasuis belongs to opportunistic microorganisms of undefined virulence. The purpose of the studies was to compare suitability of PCR/RFLP in our modification and ERIC PCR for epidemiological study of domestic strains of H...
  12. Xu C, Zhang J, Zhao Z, Guo L, Zhang B, Feng S, et al. Antimicrobial susceptibility and PFGE genotyping of Haemophilus parasuis isolates from pigs in South China (2008-2010). J Vet Med Sci. 2011;73:1061-5 pubmed
    ..Diverse variation was observed between the drug-resistant H. parasuis isolates examined, suggesting that resistance traits were acquired independently by the respective isolates...
  13. Olvera A, Cerdà Cuéllar M, Nofrarias M, Revilla E, Segales J, Aragon V. Dynamics of Haemophilus parasuis genotypes in a farm recovered from an outbreak of Glässer's disease. Vet Microbiol. 2007;123:230-7 pubmed
    b>Haemophilus parasuis is a colonizer of the upper respiratory tract of pigs, although it is better known as the etiological agent of Glässer's disease...
  14. Vanier G, Szczotka A, Friedl P, Lacouture S, Jacques M, Gottschalk M. Haemophilus parasuis invades porcine brain microvascular endothelial cells. Microbiology. 2006;152:135-42 pubmed
    b>Haemophilus parasuis, an important swine pathogen, is the aetiological agent of Glässer's disease. It is responsible for cases of polyserositis, meningitis and pneumonia in young pigs...
  15. de la Fuente A, Tucker A, Navas J, Blanco M, Morris S, Gutiérrez Martín C. Antimicrobial susceptibility patterns of Haemophilus parasuis from pigs in the United Kingdom and Spain. Vet Microbiol. 2007;120:184-91 pubmed
    A total of 30 British and 30 Spanish Haemophilus parasuis isolates were tested for their susceptibility to 19 of the antimicrobials currently used in swine practice with a broth microdilution method in order to know the emergence of ..
  16. Angen O, Svensmark B, Mittal K. Serological characterization of Danish Haemophilus parasuis isolates. Vet Microbiol. 2004;103:255-8 pubmed
    A total of 103 Danish Haemophilus parasuis field isolates was collected from diseased pigs in connection with routine diagnostics...
  17. Jung K, Chae C. In-situ hybridization for the detection of Haemophilus parasuis in naturally infected pigs. J Comp Pathol. 2004;130:294-8 pubmed
    Detection of Haemophilus parasuis in naturally infected pigs was studied by in-situ hybridization with a non-radioactive digoxigenin-labelled DNA probe...
  18. Mullins M, Register K, Brunelle B, Aragon V, Galofre Mila N, Bayles D, et al. A curated public database for multilocus sequence typing (MLST) and analysis of Haemophilus parasuis based on an optimized typing scheme. Vet Microbiol. 2013;162:899-906 pubmed publisher
    b>Haemophilus parasuis causes Glässer's disease and pneumonia in swine. Serotyping is often used to classify isolates but requires reagents that are costly to produce and not standardized or widely available...
  19. Costa Hurtado M, Olvera A, Martinez Moliner V, Galofre Mila N, Martinez P, Dominguez J, et al. Changes in macrophage phenotype after infection of pigs with Haemophilus parasuis strains with different levels of virulence. Infect Immun. 2013;81:2327-33 pubmed publisher
    b>Haemophilus parasuis is a colonizer of healthy piglets and the etiological agent of Glässer's disease. Differences in virulence among strains of H. parasuis have been widely observed...
  20. Bouchet B, Vanier G, Jacques M, Gottschalk M. Interactions of Haemophilus parasuis and its LOS with porcine brain microvascular endothelial cells. Vet Res. 2008;39:42 pubmed publisher
    b>Haemophilus parasuis is a swine pathogen that causes Glässer's disease, which is characterized by polyserositis and meningitis. The pathogenesis of the H. parasuis infection is poorly understood. To cause meningitis, H...
  21. Zehr E, Tabatabai L, Bayles D. Genomic and proteomic characterization of SuMu, a Mu-like bacteriophage infecting Haemophilus parasuis. BMC Genomics. 2012;13:331 pubmed
    b>Haemophilus parasuis, the causative agent of Glässer's disease, is prevalent in swine herds and clinical signs associated with this disease are meningitis, polyserositis, polyarthritis, and bacterial pneumonia...
  22. Chen L, Wu D, Cai X, Guo F, Blackall P, Xu X, et al. Electrotransformation of Haemophilus parasuis with in vitro modified DNA based on a novel shuttle vector. Vet Microbiol. 2012;155:310-6 pubmed publisher
    The objective of the present study was to establish a valid transformation method of Haemophilus parasuis, the causative agent of Glässer's disease in pigs, using a novel H. parasuis-Escherichia coli shuttle vector. A 4...
  23. Blanco I, Galina Pantoja L, Oliveira S, Pijoan C, Sanchez C, Canals A. Comparison between Haemophilus parasuis infection in colostrums-deprived and sow-reared piglets. Vet Microbiol. 2004;103:21-7 pubmed
    ..Ninety piglets from a commercial pig farm in Spain were used. The farm was positive for Haemophilus parasuis. Fifty-two pigs were sow-reared (SR) and 38 were colostrum-deprived (CD) piglets...
  24. del Rio M, Gutiérrez Martín C, Rodríguez Barbosa J, Navas J, Rodríguez Ferri E. Identification and characterization of the TonB region and its role in transferrin-mediated iron acquisition in Haemophilus parasuis. FEMS Immunol Med Microbiol. 2005;45:75-86 pubmed
    b>Haemophilus parasuis is the causative agent of Glässer's disease, which is responsible for considerable economic losses in the pig-rearing industry...
  25. Yu J, Wu J, Zhang Y, Guo L, Cong X, Du Y, et al. Concurrent highly pathogenic porcine reproductive and respiratory syndrome virus infection accelerates Haemophilus parasuis infection in conventional pigs. Vet Microbiol. 2012;158:316-21 pubmed publisher
    ..the effect of highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) on Haemophilus parasuis (HPS) in co-infection...
  26. Yang W, Ying F, Yingyu L, Pin C, Wentao L, Shuqing L, et al. Development and evaluation of loop-mediated isothermal amplification for rapid detection of Haemophilus parasuis. FEMS Microbiol Lett. 2010;313:54-60 pubmed publisher
    ..We developed a LAMP assay targeting the 16S rRNA gene for rapid detection of Haemophilus parasuis. The results obtained from testing 31 H...
  27. Frandoloso R, Martinez S, Rodríguez Ferri E, García Iglesias M, Perez Martinez C, Martínez Fernández B, et al. Development and characterization of protective Haemophilus parasuis subunit vaccines based on native proteins with affinity to porcine transferrin and comparison with other subunit and commercial vaccines. Clin Vaccine Immunol. 2011;18:50-8 pubmed publisher
    b>Haemophilus parasuis is the agent responsible for causing Glässer's disease, which is characterized by fibrinous polyserositis, polyarthritis, and meningitis in pigs...
  28. Zhang B, Xu C, Zhang L, Zhou S, Feng S, He Y, et al. Enhanced adherence to and invasion of PUVEC and PK-15 cells due to the overexpression of RfaD, ThyA and Mip in the ?ompP2 mutant of Haemophilus parasuis SC096 strain. Vet Microbiol. 2013;162:713-23 pubmed publisher
    ..b>Haemophilus parasuis outer membrane protein P2 (OmpP2), a member of the porin family, is an important surface protein involved ..
  29. de la Fuente A, Ferri E, Tejerina F, Frandoloso R, Martínez S, Martín C. Cytokine expression in colostrum-deprived pigs immunized and challenged with Haemophilus parasuis. Res Vet Sci. 2009;87:47-52 pubmed publisher
    ..lymph nodes, lung and brain after different immunization procedures and a challenge with 5 x 10(9) CFU of Haemophilus parasuis was compared...
  30. Metcalf D, MacInnes J. Differential expression of Haemophilus parasuis genes in response to iron restriction and cerebrospinal fluid. Can J Vet Res. 2007;71:181-8 pubmed
    b>Haemophilus parasuis is an important opportunistic pathogen in swine of high health status, but to date no proven virulence factors have been described...
  31. Tadjine M, Mittal K, Bourdon S, Gottschalk M. Production and characterization of murine monoclonal antibodies against Haemophilus parasuis and study of their protective role in mice. Microbiology. 2004;150:3935-45 pubmed
    Monoclonal antibodies (MAbs) against Haemophilus parasuis were obtained by the fusion of SP2/0-Ag14 murine myeloma cells and spleen cells from BALB/c mice immunized with a whole-bacterial-cell suspension (WC) of H...
  32. Hill C, Metcalf D, MacInnes J. A search for virulence genes of Haemophilus parasuis using differential display RT-PCR. Vet Microbiol. 2003;96:189-202 pubmed
    Although Haemophilus parasuis is an important bacterial pathogen of swine, little is known about its pathogenesis or why some strains seem to be more virulent than others...
  33. Zhou M, Guo Y, Zhao J, Hu Q, Hu Y, Zhang A, et al. Identification and characterization of novel immunogenic outer membrane proteins of Haemophilus parasuis serovar 5. Vaccine. 2009;27:5271-7 pubmed publisher
    b>Haemophilus parasuis is the aetiological agent of Glässer's disease, which is responsible for cases of fibrinous polyserositis, polyarthritis and meningitis in young pigs...
  34. Xu C, Zhang L, Zhang B, Feng S, Zhou S, Li J, et al. Involvement of lipooligosaccharide heptose residues of Haemophilus parasuis SC096 strain in serum resistance, adhesion and invasion. Vet J. 2013;195:200-4 pubmed publisher
    b>Haemophilus parasuis is the causative agent of Glässer's disease. To investigate the role of lipooligosaccharide (LOS) in H...
  35. del Rio M, Navas J, Martín A, Gutiérrez C, Rodriguez Barbosa J, Rodríguez Ferri E. Molecular characterization of Haemophilus parasuis ferric hydroxamate uptake (fhu) genes and constitutive expression of the FhuA receptor. Vet Res. 2006;37:49-59 pubmed
    ..b>Haemophilus parasuis is the causative agent of Glässer disease, which is responsible for considerable financial losses in pig-..
  36. Sack M, Baltes N. Identification of novel potential virulence-associated factors in Haemophilus parasuis. Vet Microbiol. 2009;136:382-6 pubmed publisher
    ..Determining the presence of these genes may be useful in H. parasuis diagnostics to judge a strain's potential to cause disease...
  37. Yue M, Yang F, Yang J, Bei W, Cai X, Chen L, et al. Complete genome sequence of Haemophilus parasuis SH0165. J Bacteriol. 2009;191:1359-60 pubmed publisher
    b>Haemophilus parasuis is the causative agent of Glässer's disease, which produces big losses in swine populations worldwide. H...
  38. Aragon V, Bouchet B, Gottschalk M. Invasion of endothelial cells by systemic and nasal strains of Haemophilus parasuis. Vet J. 2010;186:264-7 pubmed publisher
    b>Haemophilus parasuis is a respiratory commensal in healthy piglets, but can also produce invasive disease and meningitis, which requires the ability to cross the blood-brain barrier...
  39. Zhang B, He Y, Xu C, Xu L, Feng S, Liao M, et al. Cytolethal distending toxin (CDT) of the Haemophilus parasuis SC096 strain contributes to serum resistance and adherence to and invasion of PK-15 and PUVEC cells. Vet Microbiol. 2012;157:237-42 pubmed publisher
    ..Although two cdt gene cluster loci have been identified in Haemophilus parasuis strain SH0165, the characteristics of CDTs associated with pathogenesis remain unclear...
  40. Zhang B, Tang C, Liao M, Yue H. Update on the pathogenesis of Haemophilus parasuis infection and virulence factors. Vet Microbiol. 2014;168:1-7 pubmed publisher
    b>Haemophilus parasuis is the causative agent of Glässer's disease in pigs, a severe systemic disease that has led to increasing economic losses in the pig industry worldwide. The H...
  41. Brockmeier S, Loving C, Mullins M, Register K, Nicholson T, Wiseman B, et al. Virulence, transmission, and heterologous protection of four isolates of Haemophilus parasuis. Clin Vaccine Immunol. 2013;20:1466-72 pubmed publisher
    b>Haemophilus parasuis causes Glässer's disease, a syndrome of polyserositis, meningitis, and arthritis in swine. Previous studies with H. parasuis have revealed virulence disparity among isolates and inconsistent heterologous protection...
  42. Cerdà Cuéllar M, Aragon V. Serum-resistance in Haemophilus parasuis is associated with systemic disease in swine. Vet J. 2008;175:384-9 pubmed
    b>Haemophilus parasuis can cause pneumonia and systemic disease in swine but it is also a coloniser of the upper respiratory tract of healthy pigs...
  43. Wilkinson J, Sargent C, Galina Pantoja L, Tucker A. Gene expression profiling in the lungs of pigs with different susceptibilities to Glässer's disease. BMC Genomics. 2010;11:455 pubmed publisher
    b>Haemophilus parasuis is the causative agent of Glässer's disease in pigs. Currently, little is known about the molecular mechanisms that contribute to disease susceptibility...
  44. Oliveira S, Pijoan C. Computer-based analysis of Haemophilus parasuis protein fingerprints. Can J Vet Res. 2004;68:71-5 pubmed
    The present study aimed to compare the whole-cell protein profiles of Haemophilus parasuis field isolates by using a computer-based analysis, and evaluate the relationship between polyacrylamide gel electrophoresis (PAGE) type and ..
  45. Zhou S, Xu C, Zhang B, Feng S, Zhang L, Zou Y, et al. Natural IgG antibodies in normal rabbit serum are involved in killing of the ompP2 mutant of Haemophilus parasuis SC096 strain via the classical complement pathway. Vet J. 2013;196:111-3 pubmed publisher
    Serum resistance in Haemophilus parasuis strain SC096 has been shown to be dependent on expression of the outer membrane protein P2 (OmpP2) and loss of the ompP2 gene results in significantly greater sensitivity to both porcine and rabbit ..
  46. Zhou M, Zhang Q, Zhao J, Jin M. Haemophilus parasuis encodes two functional cytolethal distending toxins: CdtC contains an atypical cholesterol recognition/interaction region. PLoS ONE. 2012;7:e32580 pubmed publisher
    b>Haemophilus parasuis is the causative agent of Glässer's disease of pigs, a disease associated with fibrinous polyserositis, polyarthritis and meningitis. We report here H...
  47. Fu S, Ou J, Zhang M, Xu J, Liu H, Liu J, et al. The live attenuated Actinobacillus pleuropneumoniae triple-deletion mutant ?apxIC ?apxIIC ?apxIV-ORF1 strain, SLW05, Immunizes pigs against lethal challenge with Haemophilus parasuis. Clin Vaccine Immunol. 2013;20:134-9 pubmed publisher
    b>Haemophilus parasuis and Actinobacillus pleuropneumoniae both belong to the family Pasteurellaceae and are major respiratory pathogens that cause large economic losses in the pig industry worldwide...
  48. Zhang B, Feng S, Xu C, Zhou S, He Y, Zhang L, et al. Serum resistance in Haemophilus parasuis SC096 strain requires outer membrane protein P2 expression. FEMS Microbiol Lett. 2012;326:109-15 pubmed publisher
    b>Haemophilus parasuis outer membrane protein P2 (OmpP2), the most abundant protein in the outer membrane, has been identified as an antigenic protein and a potential virulence factor...
  49. Kang I, Kim D, Han K, Seo H, Oh Y, Park C, et al. Optimized protocol for multiplex nested polymerase chain reaction to detect and differentiate Haemophilus parasuis, Streptococcus suis, and Mycoplasma hyorhinis in formalin-fixed, paraffin-embedded tissues from pigs with polyserositis. Can J Vet Res. 2012;76:195-200 pubmed
    An optimized protocol was developed for the simultaneous detection and differentiation of Haemophilus parasuis, Streptococcus suis, and Mycoplasma hyorhinis in formalin-fixed, paraffin-embedded (FFPE) tissues with multiplex nested ..
  50. Tadjine M, Mittal K, Bourdon S, Gottschalk M. Development of a new serological test for serotyping Haemophilus parasuis isolates and determination of their prevalence in North America. J Clin Microbiol. 2004;42:839-40 pubmed
    b>Haemophilus parasuis causes polyserositis in swine. Fifteen serovars have been characterized by immunodiffusion test, but many field strains are not typeable. Isolates (n = 300) of H...
  51. Frandoloso R, Martínez Martínez S, Gutiérrez Martín C, Rodríguez Ferri E. Haemophilus parasuis serovar 5 Nagasaki strain adheres and invades PK-15 cells. Vet Microbiol. 2012;154:347-52 pubmed publisher
    b>Haemophilus parasuis is the agent responsible for causing Glässer's disease, which is characterized by fibrinous polyserositis, polyarthritis and meningitis in pigs...
  52. Jin H, Zhou R, Kang M, Luo R, Cai X, Chen H. Biofilm formation by field isolates and reference strains of Haemophilus parasuis. Vet Microbiol. 2006;118:117-23 pubmed
    The ability to form biofilms for a total of 80 field isolates and 15 reference strains of Haemophilus parasuis, the etiological agent of Glasser's disease, was tested by glass tube and polystyrene microtiter plate assays...
  53. Zhou H, Yang B, Xu F, Chen X, Wang J, Blackall P, et al. Identification of putative virulence-associated genes of Haemophilus parasuis through suppression subtractive hybridization. Vet Microbiol. 2010;144:377-83 pubmed publisher
    b>Haemophilus parasuis is the causative agent of Glässer's disease. Up to now 15 serovars of H. parasuis have been identified, with significant differences existing in virulence between serovars...
  54. Bigas A, Garrido M, de Rozas A, Badiola I, Barb J, Llagostera M. Development of a genetic manipulation system for Haemophilus parasuis. Vet Microbiol. 2005;105:223-8 pubmed publisher
    b>Haemophilus parasuis is a member of the family Pasteurellaceae and an important respiratory-tract pathogen of swine, which is the etiological agent of Glasser's disease. Because no genetic manipulation system is available for H...
  55. McVicker J, Tabatabai L. Isolation and characterization of the P5 adhesin protein of Haemophilus parasuis serotype 5. Prep Biochem Biotechnol. 2006;36:363-74 pubmed
    b>Haemophilus parasuis is a Gram-negative respiratory pathogen of young pigs that colonizes the upper respiratory tract and produces a number of symptoms collectiviely described as Glässer's disease. Recently, an H...
  56. Li Y, Kwok A, Jiang J, Zou Y, Zheng F, Chen P, et al. Complete genome analysis of a Haemophilus parasuis serovar 12 strain from China. PLoS ONE. 2013;8:e68350 pubmed publisher
    b>Haemophilus parasuis is the etiological agent of Glässer's disease in pigs and 15 standard serovars were identified. The widespread disease causes great economic loss in the swine industry worldwide...
  57. Fu S, Yuan F, Zhang M, Tan C, Chen H, Bei W. Cloning, expression and characterization of a cell wall surface protein, 6-phosphogluconate dehydrogenase, of Haemophilus parasuis. Res Vet Sci. 2012;93:57-62 pubmed publisher
    b>Haemophilus parasuis (H. parasuis) is a swine pathogen responsible for the Glässer's disease. In order to understand the pathogenesis of the H...
  58. Chen H, Lunney J, Cheng L, Li X, Cao J, Zhu M, et al. Porcine S100A8 and S100A9: molecular characterizations and crucial functions in response to Haemophilus parasuis infection. Dev Comp Immunol. 2011;35:490-500 pubmed publisher
    ..We previously showed that pS100A8 and pS100A9 mRNA were up-regulated following Haemophilus parasuis (HPS) infection...
  59. Oliveira S, Pijoan C. Haemophilus parasuis: new trends on diagnosis, epidemiology and control. Vet Microbiol. 2004;99:1-12 pubmed
    b>Haemophilus parasuis is a commensal organism of the upper respiratory tract of conventional pigs, but under appropriate conditions can invade and cause severe systemic disease, characterized by fibrinous polyserositis, arthritis and ..
  60. Cerdà Cuéllar M, Naranjo J, Verge A, Nofrarias M, Cortey M, Olvera A, et al. Sow vaccination modulates the colonization of piglets by Haemophilus parasuis. Vet Microbiol. 2010;145:315-20 pubmed publisher
    b>Haemophilus parasuis is the etiologic agent of Glässer's disease in pigs and a colonizer of the upper respiratory tract of healthy pigs. A good balance between colonization and immunity is important to avoid a disease outbreak...
  61. Martínez Martínez S, Frandoloso R, Gutiérrez Martín C, Lampreave F, García Iglesias M, Perez Martinez C, et al. Acute phase protein concentrations in colostrum-deprived pigs immunized with subunit and commercial vaccines against Glässer's disease. Vet Immunol Immunopathol. 2011;144:61-7 pubmed publisher
    b>Haemophilus parasuis is the etiological agent of Glässer's disease, which is characterized by fibrinous polyserositis, polyarthritis and meningitis in pigs...
  62. Blanco I, Canals A, Evans G, Mellencamp M, Cia C, Deeb N, et al. Differences in susceptibility to Haemophilus parasuis infection in pigs. Can J Vet Res. 2008;72:228-35 pubmed
    ..Tissues from this population could be used to identify DNA markers for genetic selection of sires that produce offspring more resistant to H. parasuis infection...
  63. Aragon V, Cerdà Cuéllar M, Fraile L, Mombarg M, Nofrarias M, Olvera A, et al. Correlation between clinico-pathological outcome and typing of Haemophilus parasuis field strains. Vet Microbiol. 2010;142:387-93 pubmed publisher
    b>Haemophilus parasuis is the etiologic agent of Glässer's disease in pigs, which is pathologically characterized by serofibrinous polyserositis and arthritis. H...
  64. Olvera A, Calsamiglia M, Aragon V. Genotypic diversity of Haemophilus parasuis field strains. Appl Environ Microbiol. 2006;72:3984-92 pubmed
    b>Haemophilus parasuis is the cause of Glässer's disease and other clinical disorders in pigs. It can also be isolated from the upper respiratory tracts of healthy pigs, and isolates can have significant differences in virulence...
  65. de la Fuente A, Gutiérrez Martín C, Rodriguez Barbosa J, Martinez Martinez S, Frandoloso R, Tejerina F, et al. Blood cellular immune response in pigs immunized and challenged with Haemophilus parasuis. Res Vet Sci. 2009;86:230-4 pubmed publisher
    The cellular immune response to an experimental infection by Haemophilus parasuis, the etiological agent of Glässer's disease in pigs, was characterized studying changes in peripheral blood mononuclear cells (PBMC) in colostrum-deprived ..
  66. Jin H, Wan Y, Zhou R, Li L, Luo R, Zhang S, et al. Identification of genes transcribed by Haemophilus parasuis in necrotic porcine lung through the selective capture of transcribed sequences (SCOTS). Environ Microbiol. 2008;10:3326-36 pubmed publisher
    b>Haemophilus parasuis is the aetiological agent of Glässer's disease, which has received more attention in the past decade due to the increasing economic losses in the pig industry worldwide...
  67. Cai X, Chen H, Blackall P, Yin Z, Wang L, Liu Z, et al. Serological characterization of Haemophilus parasuis isolates from China. Vet Microbiol. 2005;111:231-6 pubmed
    From September 2002 to December 2004, a total of 281 strains of Haemophilus parasuis were isolated from 17 provinces of China. All these isolates were serotyped by both the gel diffusion (GD) and the indirect haemagglutination (IHA) tests...
  68. Macedo N, Oliveira S, Lage A, Santos J, Araújo M, Guedes R. ERIC-PCR genotyping of Haemophilus parasuis isolates from Brazilian pigs. Vet J. 2011;188:362-4 pubmed publisher
    Among 63 Haemophilus parasuis isolates from 17 Brazilian pig herds, 33 genotypes were identified by enterobacterial repetitive intergenic consensus (ERIC)-PCR, with a diversity index of 0.96...
  69. Olvera A, Pina S, Macedo N, Oliveira S, Aragon V, Bensaid A. Identification of potentially virulent strains of Haemophilus parasuis using a multiplex PCR for virulence-associated autotransporters (vtaA). Vet J. 2012;191:213-8 pubmed publisher
    b>Haemophilus parasuis is the aetiological agent of Glässer's disease and is also a commensal of the upper respiratory tract of pigs. Trimeric autotransporter (vtaA) genes have been identified in H...
  70. Turni C, Blackall P. Comparison of the indirect haemagglutination and gel diffusion test for serotyping Haemophilus parasuis. Vet Microbiol. 2005;106:145-51 pubmed
    ..was to compare the use of indirect haemagglutination (IHA) and gel diffusion (GD) tests for serotyping Haemophilus parasuis by the Kielstein-Rapp-Gabrielson (KRG) scheme...
  71. Olvera A, Ballester M, Nofrarias M, Sibila M, Aragon V. Differences in phagocytosis susceptibility in Haemophilus parasuis strains. Vet Res. 2009;40:24 pubmed publisher
    b>Haemophilus parasuis is a colonizer of the upper respiratory tract of healthy pigs, but virulent strains can cause a systemic infection characterized by fibrinous polyserositis, commonly known as Glässer's disease...
  72. Olvera A, Pina S, Pérez Simó M, Aragon V, Segales J, Bensaid A. Immunogenicity and protection against Haemophilus parasuis infection after vaccination with recombinant virulence associated trimeric autotransporters (VtaA). Vaccine. 2011;29:2797-802 pubmed publisher
    b>Haemophilus parasuis is the etiological agent of Glässer's disease in swine, characterized by fibrinous polyserositis, polyarthritis and meningitis...