haemophilus

Summary

Summary: A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.

Top Publications

  1. Murphy T, Brauer A, Sethi S, Kilian M, Cai X, Lesse A. Haemophilus haemolyticus: a human respiratory tract commensal to be distinguished from Haemophilus influenzae. J Infect Dis. 2007;195:81-9 pubmed
    b>Haemophilus influenzae is a common pathogen in adults with chronic obstructive pulmonary disease (COPD). In a prospective study, selected isolates of apparent H. influenzae had an altered phenotype...
  2. Bak H, Riising H. Protection of vaccinated pigs against experimental infections with homologous and heterologous Haemophilus parasuis. Vet Rec. 2002;151:502-5 pubmed
    The efficacy of a new Haemophilus parasuis vaccine for pigs was investigated. The vaccine contains H parasuis serotype 5 cells and is adjuvanted with Diluvac Forte (Intervet)...
  3. Mukundan D, Ecevit Z, Patel M, Marrs C, Gilsdorf J. Pharyngeal colonization dynamics of Haemophilus influenzae and Haemophilus haemolyticus in healthy adult carriers. J Clin Microbiol. 2007;45:3207-17 pubmed
    b>Haemophilus influenzae is an important cause of respiratory infections, including acute otitis media, sinusitis, and chronic bronchitis, which are preceded by asymptomatic H. influenzae colonization of the human pharynx...
  4. McDermott P, Barry A, Jones R, Stein G, Thornsberry C, Wu C, et al. Standardization of broth microdilution and disk diffusion susceptibility tests for Actinobacillus pleuropneumoniae and Haemophilus somnus: quality control standards for ceftiofur, enrofloxacin, florfenicol, gentamicin, penicillin, tetracycline, tilmi. J Clin Microbiol. 2001;39:4283-7 pubmed
    ..susceptibility testing of two fastidious veterinary pathogens, Actinobacillus pleuropneumoniae and Haemophilus somnus, were developed in a multilaboratory study according to procedures established by the National Committee ..
  5. Martin K, Morlin G, Smith A, Nordyke A, Eisenstark A, Golomb M. The tryptophanase gene cluster of Haemophilus influenzae type b: evidence for horizontal gene transfer. J Bacteriol. 1998;180:107-18 pubmed
    Among strains of Haemophilus influenzae, the ability to catabolize tryptophan (as detected by indole production) varies and is correlated with pathogenicity...
  6. Couturier M, Mehinovic E, Croft A, Fisher M. Identification of HACEK clinical isolates by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol. 2011;49:1104-6 pubmed publisher
    ..We assessed this technology for the identification of 103 Haemophilus parainfluenzae, Aggregatibacter aphrophilus, Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, ..
  7. O Reilly T, Niven D. Levels of nicotinamide adenine dinucleotide in extracellular body fluids of pigs may be growth-limiting for Actinobacillus pleuropneumoniae and Haemophilus parasuis. Can J Vet Res. 2003;67:229-31 pubmed
    ..Actinobacillus pleuropneumoniae (biotype 1) and Haemophilus parasuis, respiratory tract pathogens of swine, are both V-factor-dependent...
  8. Oliveira S, Batista L, Torremorell M, Pijoan C. Experimental colonization of piglets and gilts with systemic strains of Haemophilus parasuis and Streptococcus suis to prevent disease. Can J Vet Res. 2001;65:161-7 pubmed
    b>Haemophilus parasuis and Streptococcus suis are both major causes of losses during the nursery period, especially in herds using the segregated early weaning system...
  9. Nørskov Lauritsen N. Detection of cryptic genospecies misidentified as Haemophilus influenzae in routine clinical samples by assessment of marker genes fucK, hap, and sodC. J Clin Microbiol. 2009;47:2590-2 pubmed publisher
    Clinical isolates of Haemophilus influenzae were assessed for the presence of fucK, hap, and sodC by hybridization with gene-specific probes, and isolates diverging from the expected H...

More Information

Publications70

  1. Lancashire J, Terry T, Blackall P, Jennings M. Plasmid-encoded Tet B tetracycline resistance in Haemophilus parasuis. Antimicrob Agents Chemother. 2005;49:1927-31 pubmed publisher
    The complete sequence of two plasmids, pHS-Tet (5.1 kb) and pHS-Rec (9.5 kb), isolated from Haemophilus parasuis strain HS1543 has been obtained...
  2. Gunn J, Stein D. The Neisseria gonorrhoeae S.NgoVIII restriction/modification system: a type IIs system homologous to the Haemophilus parahaemolyticus HphI restriction/modification system. Nucleic Acids Res. 1997;25:4147-52 pubmed
    ..the dcmH and damH genes, as well as an open reading frame downstream of the damH gene are highly similar to the Haemophilus parahaemolyticus hphIMC , hphIMA and hphIR gene products, encoding the Hph I Type IIs R-M system. The S...
  3. Sheets A, Grass S, Miller S, St Geme J. Identification of a novel trimeric autotransporter adhesin in the cryptic genospecies of Haemophilus. J Bacteriol. 2008;190:4313-20 pubmed publisher
    b>Haemophilus biotype IV strains belonging to the recently recognized Haemophilus cryptic genospecies are an important cause of maternal genital tract and neonatal systemic infections and initiate infection by colonizing the genital or ..
  4. Cole S, Guiney D, Corbeil L. Molecular analysis of a gene encoding a serum-resistance-associated 76 kDa surface antigen of Haemophilus somnus. J Gen Microbiol. 1993;139:2135-43 pubmed publisher
    b>Haemophilus somnus is a Gram-negative bacterial bovine pathogen which can cause disease or be carried asymptomatically. We previously showed that four serum-sensitive isolates from asymptomatic carriers lacked a 13...
  5. Oliveira S, Blackall P, Pijoan C. Characterization of the diversity of Haemophilus parasuis field isolates by use of serotyping and genotyping. Am J Vet Res. 2003;64:435-42 pubmed
    To characterize the genetic diversity of Haemophilus parasuis field isolates with regard to serovar, herd of origin, and site of isolation.
  6. Segales J, Domingo M, Solano G, Pijoan C. Porcine reproductive and respiratory syndrome virus and Haemophilus parasuis antigen distribution in dually infected pigs. Vet Microbiol. 1999;64:287-97 pubmed
    ..to study the distribution and localization of porcine reproductive and respiratory syndrome virus (PRRSV) and Haemophilus (H.) parasuis in experimentally infected pigs. Thirty pigs seronegative to PRRSV and H...
  7. Lau S, Woo P, Chan B, Fung A, Que T, Yuen K. Haemophilus segnis polymicrobial and monomicrobial bacteraemia identified by 16S ribosomal RNA gene sequencing. J Med Microbiol. 2002;51:635-40 pubmed
    This paper reports a case of Haemophilus segnis polymicrobial bacteraemia and a case of H. segnis monomicrobial bacteraemia identified by 16S ribosomal RNA gene sequencing...
  8. Hedegaard J, Okkels H, Bruun B, Kilian M, Mortensen K, Nørskov Lauritsen N. Phylogeny of the genus Haemophilus as determined by comparison of partial infB sequences. Microbiology. 2001;147:2599-609 pubmed
    ..translation initiation factor 2, was sequenced and compared from 66 clinical isolates and type strains of Haemophilus species and related bacteria...
  9. Gardner H, DUKES C. Haemophilus vaginalis vaginitis: a newly defined specific infection previously classified non-specific vaginitis. Am J Obstet Gynecol. 1955;69:962-76 pubmed
  10. Kirkham L, Wiertsema S, Mowe E, Bowman J, Riley T, Richmond P. Nasopharyngeal carriage of Haemophilus haemolyticus in otitis-prone and healthy children. J Clin Microbiol. 2010;48:2557-9 pubmed publisher
    b>Haemophilus haemolyticus is often incorrectly categorized as nontypeable Haemophilus influenzae (NTHI) upon culture...
  11. Del Rio M, Gutierrez C, Rodriguez Ferri E. Value of indirect hemagglutination and coagglutination tests for serotyping Haemophilus parasuis. J Clin Microbiol. 2003;41:880-2 pubmed
    ..and a coagglutination test (CA) were evaluated using saline, boiled, and autoclaved extracts for serotyping Haemophilus parasuis. CA showed several cross-reactions, whereas IHA gave rise to specific reactions, with minor exceptions...
  12. Hare K, Binks M, Grimwood K, Chang A, Leach A, Smith Vaughan H. Culture and PCR detection of Haemophilus influenzae and Haemophilus haemolyticus in Australian Indigenous children with bronchiectasis. J Clin Microbiol. 2012;50:2444-5 pubmed publisher
    A PCR for protein D (hpd#3) was used to differentiate nontypeable Haemophilus influenzae (NTHI) from Haemophilus haemolyticus...
  13. Anderson R, Wang X, Briere E, Katz L, Cohn A, Clark T, et al. Haemophilus haemolyticus isolates causing clinical disease. J Clin Microbiol. 2012;50:2462-5 pubmed publisher
    We report seven cases of Haemophilus haemolyticus invasive disease detected in the United States, which were previously misidentified as nontypeable Haemophilus influenzae. All cases had different symptoms and presentations...
  14. Williams P, Morton D, Towner K, Stevenson P, Griffiths E. Utilization of enterobactin and other exogenous iron sources by Haemophilus influenzae, H. parainfluenzae and H. paraphrophilus. J Gen Microbiol. 1990;136:2343-50 pubmed
    The ability of Haemophilus influenzae, H. parainfluenzae and H. paraphrophilus to utilize iron complexes, iron-proteins and exogenous microbial siderophores was evaluated...
  15. Totten P, Amsel R, Hale J, Piot P, Holmes K. Selective differential human blood bilayer media for isolation of Gardnerella (Haemophilus) vaginalis. J Clin Microbiol. 1982;15:141-7 pubmed
    ..media with Tween 80 (HBT medium) or without Tween 80 (HB medium), developed for the isolation of Gardnerella (Haemophilus) vaginalis, permitted significantly higher G...
  16. Peak I, Jennings M, Hood D, Bisercic M, Moxon E. Tetrameric repeat units associated with virulence factor phase variation in Haemophilus also occur in Neisseria spp. and Moraxella catarrhalis. FEMS Microbiol Lett. 1996;137:109-14 pubmed
    ..and 5'-GCAA-3' are associated with phase variable expression of lipopolysaccharide biosynthetic genes in Haemophilus influenzae. Four other tetrameric repeat units have also been reported from H...
  17. Fung W, O dwyer C, Sinha S, Brauer A, Murphy T, Kroll J, et al. Presence of copper- and zinc-containing superoxide dismutase in commensal Haemophilus haemolyticus isolates can be used as a marker to discriminate them from nontypeable H. influenzae isolates. J Clin Microbiol. 2006;44:4222-6 pubmed
    Respiratory isolates of Haemophilus haemolyticus are regularly misclassified as nontypeable (NT) Haemophilus influenzae due to an aberrant hemolytic reaction on blood agar, with implications for treatment...
  18. Cash P, Argo E, Langford P, Kroll J. Development of a Haemophilus two-dimensional protein database. Electrophoresis. 1997;18:1472-82 pubmed
    Members of the Haemophilus genus are responsible for various human infections including respiratory infections and meningitis...
  19. Charland N, D Silva C, Dumont R, Niven D. Contact-dependent acquisition of transferrin-bound iron by two strains of Haemophilus parasuis. Can J Microbiol. 1995;41:70-4 pubmed
    Two strains of Haemophilus parasuis, namely, the type strain (ATCC 19417) and strain E751, were investigated with respect to iron acquisition...
  20. Lichtensteiger C, Vimr E. Purification and renaturation of membrane neuraminidase from Haemophilus parasuis. Vet Microbiol. 2003;93:79-87 pubmed
    b>Haemophilus parasuis, which causes polyserositis, polysynovitis, meningitis, septicemia, and pneumonia in pigs, has emerged as an increasing problem in modern swine production systems. Co-factors for and the pathogenesis of H...
  21. Rennie R, Brosnikoff C, Shokoples S, Reller L, Mirrett S, Janda W, et al. Multicenter evaluation of the new Vitek 2 Neisseria-Haemophilus identification card. J Clin Microbiol. 2008;46:2681-5 pubmed publisher
    The new Neisseria-Haemophilus identification (NH) card for Vitek 2 was compared with 16S rRNA gene sequencing (16S) as the reference method for accurate identification of Neisseria spp., Haemophilus spp...
  22. Lubys A, Lubiene J, Kulakauskas S, Stankevicius K, Timinskas A, Janulaitis A. Cloning and analysis of the genes encoding the type IIS restriction-modification system HphI from Haemophilus parahaemolyticus. Nucleic Acids Res. 1996;24:2760-6 pubmed
    ..R-M) system HphI (enzymes recognizing the asymmetric sequence 5'-GGTGA-3'/5'-TCACC-3') from Haemophilus parahaemolyticus were cloned into Escherichia coli and sequenced...
  23. Juhas M, Dimopoulou I, Robinson E, Elamin A, Harding R, Hood D, et al. Identification of another module involved in the horizontal transfer of the Haemophilus genomic island ICEHin1056. Plasmid. 2013;70:277-83 pubmed publisher
    A significant part of horizontal gene transfer is facilitated by genomic islands. Haemophilus influenzae genomic island ICEHin1056 is an archetype of a genomic island that accounts for pandemic spread of antibiotics resistance...
  24. Sethi S, Sethi R, Eschberger K, Lobbins P, Cai X, Grant B, et al. Airway bacterial concentrations and exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007;176:356-61 pubmed
    ..Bacterial concentrations are higher during exacerbation than during stable disease; however, these studies are cross sectional and devoid of strain typing...
  25. Oliveira S, Galina L, Blanco I, Canals A, Pijoan C. Naturally-farrowed, artificially-reared pigs as an alternative model for experimental infection by Haemophilus parasuis. Can J Vet Res. 2003;67:146-50 pubmed
    The use of naturally-farrowed, artificially-reared piglets as an alternative model to study Haemophilus parasuis infections was evaluated. Two trials were performed in order to evaluate the proposed model...
  26. McCrea K, Xie J, LaCross N, Patel M, Mukundan D, Murphy T, et al. Relationships of nontypeable Haemophilus influenzae strains to hemolytic and nonhemolytic Haemophilus haemolyticus strains. J Clin Microbiol. 2008;46:406-16 pubmed
    b>Haemophilus influenzae is both a human respiratory pathogen and pharyngeal commensal, while H. haemolyticus, the closest phylogenetic relative of H. influenzae, is arguably a strict pharyngeal commensal...
  27. Gogolewski R, Leathers C, Liggitt H, Corbeil L. Experimental Haemophilus somnus pneumonia in calves and immunoperoxidase localization of bacteria. Vet Pathol. 1987;24:250-6 pubmed
    Pneumonia was produced in nine, conventionally reared calves by intrabronchial inoculation with Haemophilus somnus. Volumes of pneumonic lung were determined stereologically, following serial slicing of lungs fixed by vascular perfusion...
  28. Hanson M, Slaughter C, Hansen E. The hbpA gene of Haemophilus influenzae type b encodes a heme-binding lipoprotein conserved among heme-dependent Haemophilus species. Infect Immun. 1992;60:2257-66 pubmed
    A membrane-associated lipoprotein of Haemophilus influenzae type b has previously been shown to bind heme in vitro and to promote binding of this compound by Escherichia coli recombinants expressing this protein. The H...
  29. Hotomi M, Kono M, Togawa A, Arai J, Takei S, Ikeda Y, et al. Haemophilus influenzae and Haemophilus haemolyticus in tonsillar cultures of adults with acute pharyngotonsillitis. Auris Nasus Larynx. 2010;37:594-600 pubmed publisher
    The aim of this study was to evaluate the clinical implication of Haemophilus haemolyticus, one of the closest relative of Haemophilus influenzae, on acute pharyngotonsillitis.
  30. Valenza G, Ruoff C, Vogel U, Frosch M, Abele Horn M. Microbiological evaluation of the new VITEK 2 Neisseria-Haemophilus identification card. J Clin Microbiol. 2007;45:3493-7 pubmed
    ..VITEK 2 is an automated identification system for diverse bacterial and fungal species. A new card (the Neisseria-Haemophilus [NH] card) for the identification of Neisseria spp., Haemophilus spp...
  31. McCrea K, Xie J, Marrs C, Gilsdorf J. Prevalence of genetic differences in phosphorylcholine expression between nontypeable Haemophilus influenzae and Haemophilus haemolyticus. BMC Microbiol. 2010;10:286 pubmed publisher
    Although non-typeable (NT) Haemophilus influenzae and Haemophilus haemolyticus are closely related human commensals, H. haemolyticus is non-pathogenic while NT H. influenzae is an important cause of respiratory tract infections...
  32. Lichtensteiger C, Vimr E. Neuraminidase (sialidase) activity of Haemophilus parasuis. FEMS Microbiol Lett. 1997;152:269-74 pubmed
    Neuraminidase (sialidase), a potential virulence factor in bacteria, was demonstrated in Haemophilus parasuis, an invasive swine pathogen, but not in four other pathogens of the Pasteurellaceae family: H. influenzae, H. somnus, H...
  33. Huang S, Lee H, Lee N, Liu K, Ko W. Clinical characteristics of invasive Haemophilus aphrophilus infections. J Microbiol Immunol Infect. 2005;38:271-6 pubmed
    b>Haemophilus aphrophilus, an oral fastidious Gram-negative commensal with low pathogenicity, is a member of the HACEK group (H. aphrophilus, H...
  34. Nørskov Lauritsen N, Kilian M. Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatib. Int J Syst Evol Microbiol. 2006;56:2135-46 pubmed
    ..the relationships and the generic affiliations of the species Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis...
  35. Chang A, Adlowitz D, Yellamatty E, Pichichero M. Haemophilus influenzae outer membrane protein P6 molecular characterization may not differentiate all strains of H. Influenzae from H. haemolyticus. J Clin Microbiol. 2010;48:3756-7 pubmed publisher
    Distinguishing nontypeable Haemophilus influenzae and Haemophilus haemolyticus isolates by outer membrane protein (OMP) P6 gene sequencing is complicated by sequence variants in isolates...
  36. Ruiz A, Oliveira S, Torremorell M, Pijoan C. Outer membrane proteins and DNA profiles in strains of Haemophilus parasuis recovered from systemic and respiratory sites. J Clin Microbiol. 2001;39:1757-62 pubmed
    Polyserositis caused by Haemophilus parasuis is an important disease that affects mostly weaned pigs...
  37. Kilian M, Poulsen K, Lomholt H. Evolution of the paralogous hap and iga genes in Haemophilus influenzae: evidence for a conserved hap pseudogene associated with microcolony formation in the recently diverged Haemophilus aegyptius and H. influenzae biogroup aegyptius. Mol Microbiol. 2002;46:1367-80 pubmed
    Certain non-capsulate strains belonging to the Haemophilus influenzae/Haemophilus aegyptius complex show unusually high pathogenicity, but the evolutionary origin of these virulent phenotypes, termed H...
  38. Sylte M, Corbeil L, Inzana T, Czuprynski C. Haemophilus somnus induces apoptosis in bovine endothelial cells in vitro. Infect Immun. 2001;69:1650-60 pubmed
    b>Haemophilus somnus causes pneumonia, reproductive failure, infectious myocarditis, thrombotic meningoencephalitis, and other diseases in cattle. Although vasculitis is commonly seen as a result of systemic H...
  39. Szelestey B, Heimlich D, Raffel F, Justice S, Mason K. Haemophilus responses to nutritional immunity: epigenetic and morphological contribution to biofilm architecture, invasion, persistence and disease severity. PLoS Pathog. 2013;9:e1003709 pubmed publisher
    ..that fluctuations in heme-iron availability, particularly at privileged sites, would similarly influence Haemophilus biofilm formation and pathogenesis...
  40. Wong S, Bernui M, Shen H, Akerley B. Genome-wide fitness profiling reveals adaptations required by Haemophilus in coinfection with influenza A virus in the murine lung. Proc Natl Acad Sci U S A. 2013;110:15413-8 pubmed publisher
    ..The bacterium Haemophilus influenzae typically colonizes the human upper respiratory tract without causing disease, and yet in ..
  41. Zhu B, Xiao D, Zhang H, Zhang Y, Gao Y, Xu L, et al. MALDI-TOF MS distinctly differentiates nontypable Haemophilus influenzae from Haemophilus haemolyticus. PLoS ONE. 2013;8:e56139 pubmed publisher
    Nontypable Haemophilus influenzae (NTHi) and Haemophilus haemolyticus exhibit different pathogenicities, but to date, there remains no definitive and reliable strategy for differentiating these strains...
  42. Sethi S, Murphy T. Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review. Clin Microbiol Rev. 2001;14:336-63 pubmed
    ..Nontypeable Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae are the most common causes of exacerbations, ..
  43. Vitiazeva V, Twelkmeyer B, Young R, Hood D, Schweda E. Structural studies of the lipopolysaccharide from Haemophilus parainfluenzae strain 20. Carbohydr Res. 2011;346:2228-36 pubmed publisher
    b>Haemophilus parainfluenzae is a Gram-negative bacterium that colonizes the upper respiratory tract of humans and is a part of normal flora. In this study, we investigated the lipopolysaccharide (LPS) expressed by H...
  44. Theisen M, Rioux C, Potter A. Molecular cloning, nucleotide sequence, and characterization of lppB, encoding an antigenic 40-kilodalton lipoprotein of Haemophilus somnus. Infect Immun. 1993;61:1793-8 pubmed
    b>Haemophilus somnus is a facultative intracellular pathogen which causes a wide range of diseases in cattle. To identify putative virulence determinants, a genomic library of H...
  45. Howard M, Boone J, Buechner Maxwell V, Schurig G, Inzana T. Inhibition of bovine macrophage and polymorphonuclear leukocyte superoxide anion production by Haemophilus somnus. Microb Pathog. 2004;37:263-71 pubmed
    Virulent strains of the bovine opportunistic pathogen Haemophilus somnus (Histophilus somni) cause multi-systemic diseases in cattle. One of the reported virulence factors that H...
  46. Gianninò V, Rappazzo G, Scuto A, Di Marco O, Privitera A, Santagati M, et al. rrn operons in Haemophilus parainfluenzae and mosaicism of conserved and species-specific sequences in the 16S-23S rDNA long spacer. Res Microbiol. 2001;152:461-8 pubmed
    ..organisation of short-sequence boxes was analysed in the cloned and sequenced long ribosomal spacer (547 bp) of Haemophilus parainfluenzae GR. Comparison and alignment of both the long and the short spacer were performed in H...
  47. Oliveira S, Galina L, Pijoan C. Development of a PCR test to diagnose Haemophilus parasuis infections. J Vet Diagn Invest. 2001;13:495-501 pubmed
    A polymerase chain reaction (PCR) test was developed in order to improve the accuracy and speed of diagnosis of Haemophilus parasuis, an economically important respiratory pathogen that affects swine...
  48. McCrea K, Wang M, Xie J, Sandstedt S, Davis G, Lee J, et al. Prevalence of the sodC gene in nontypeable Haemophilus influenzae and Haemophilus haemolyticus by microarray-based hybridization. J Clin Microbiol. 2010;48:714-9 pubmed publisher
    The sodC gene has been reported to be a useful marker for differentiating nontypeable (NT) Haemophilus influenzae from Haemophilus haemolyticus in respiratory-tract samples, but discrepancies exist as to the prevalence of sodC in NT H...
  49. de la Puente Redondo V, Navas Méndez J, García del Blanco N, Ladrón Boronat N, Gutiérrez Martín C, Rodriguez Ferri E. Typing of Haemophilus parasuis strains by PCR-RFLP analysis of the tbpA gene. Vet Microbiol. 2003;92:253-62 pubmed
    On the basis of a species-specific PCR assay, a RFLP analysis for typing of Haemophilus parasuis strains was developed and evaluated. Amplification was based on the gene tbpA, encoding a transferrin-binding protein...
  50. Angen O, Ahrens P, Tegtmeier C. Development of a PCR test for identification of Haemophilus somnus in pure and mixed cultures. Vet Microbiol. 1998;63:39-48 pubmed
    Based on the 16S rRNA sequences of a collection of well-characterized strains of Haemophilus somnus a set of primers was selected as candidates for a species-specific PCR test. All investigated H...
  51. Rúbies X, Kielstein P, Costa L, Riera P, Artigas C, Espuna E. Prevalence of Haemophilus parasuis serovars isolated in Spain from 1993 to 1997. Vet Microbiol. 1999;66:245-8 pubmed
    From 1993 to 1997, 327 strains of Haemophilus parasuis were isolated from spanish swine in our Diagnostic Laboratory and 174 strains (53.2%) were serotyped. Four serotypes, sv. 5 (18.4%), sv 4 (16%), sv. 2 (9.2%) and sv...
  52. Piekarowicz A, Golaszewska M, Sunday A, Siwinska M, Stein D. The HaeIV restriction modification system of Haemophilus aegyptius is encoded by a single polypeptide. J Mol Biol. 1999;293:1055-65 pubmed
    ..The gene encoding the HaeIV ENase was cloned from Haemophilus aegyptius into pUC19 using a previously described system that does not need the knowledge that a particular ..
  53. Akhondi H, Rahimi A. Haemophilus aphrophilus endocarditis after tongue piercing. Emerg Infect Dis. 2002;8:850-1 pubmed
  54. Lima J, Ribeiro G, Cordeiro S, Gouveia E, Salgado K, Spratt B, et al. Poor clinical outcome for meningitis caused by Haemophilus influenzae serotype A strains containing the IS1016-bexA deletion. J Infect Dis. 2010;202:1577-84 pubmed publisher
    Since the introduction of Haemophilus influenzae type b (Hib) conjugate vaccines, meningitis caused by serotypes other than Hib has gained in importance...
  55. Inzana T, Hensley J, McQuiston J, Lesse A, Campagnari A, Boyle S, et al. Phase variation and conservation of lipooligosaccharide epitopes in Haemophilus somnus. Infect Immun. 1997;65:4675-81 pubmed
    The bovine-specific pathogen Haemophilus somnus is capable of undergoing structural and antigenic phase variation in its lipooligosaccharide (LOS) components after in vivo and in vitro passage...
  56. Corbeil L, Bastida Corcuera F, Beveridge T. Haemophilus somnus immunoglobulin binding proteins and surface fibrils. Infect Immun. 1997;65:4250-7 pubmed
    The high-molecular-weight (HMW) immunoglobulin binding proteins (IgBPs) of Haemophilus somnus and a 76-kDa surface protein (p76) are found in serum-resistant virulent strains but not in several serum-sensitive strains from asymptomatic ..
  57. Petti C, Bhally H, Weinstein M, Joho K, Wakefield T, Reller L, et al. Utility of extended blood culture incubation for isolation of Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella organisms: a retrospective multicenter evaluation. J Clin Microbiol. 2006;44:257-9 pubmed
    The incidence of and average time to detection for Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella (HACEK) bacteria in blood cultures with standard incubation and the utility of extended incubation of blood culture ..
  58. Yamamoto C, Suzuki S, Kimura H, Yoshida H, Gejyo F. Experimental nephropathy induced by Haemophilus parainfluenzae antigens. Nephron. 2002;90:320-7 pubmed
    We have demonstrated that outer membrane antigens of Haemophilus parainfluenzae (OMHP) are potentially involved in IgA nephropathy (IgAN)...
  59. Chien J, Lin C, Chen Y, Lay C, Wang C, Tsai C. Epidural abscess caused by Haemophilus aphrophilus misidentified as Pasteurella species. Intern Med. 2009;48:853-8 pubmed
    b>Haemophilus aphrophilus is one of the normal oropharyngeal flora and rarely implicated as a pathogen of spinal infection. A case of H...
  60. Smith A, Erwin A, Kline T, Unrath W, Nelson K, Weber A, et al. Chloramphenicol is a substrate for a novel nitroreductase pathway in Haemophilus influenzae. Antimicrob Agents Chemother. 2007;51:2820-9 pubmed
    ..antibiotic chloramphenicol has been used extensively to treat life-threatening infections due to Haemophilus influenzae and Neisseria meningitidis; its mechanism of action is the inhibition of protein synthesis...
  61. Angen Ø, Ahrens P, Kuhnert P, Christensen H, Mutters R. Proposal of Histophilus somni gen. nov., sp. nov. for the three species incertae sedis 'Haemophilus somnus', 'Haemophilus agni' and 'Histophilus ovis'. Int J Syst Evol Microbiol. 2003;53:1449-56 pubmed
    Earlier investigations have shown that 'Haemophilus somnus', 'Haemophilus agni' and 'Histophilus ovis' represent the same species...