sinorhizobium meliloti

Summary

Summary: A species of gram-negative, aerobic bacteria that causes formation of root nodules on some, but not all, types of sweet clover, MEDICAGO SATIVA, and fenugreek.

Top Publications

  1. Pistorio M, Giusti M, Del Papa M, Draghi W, Lozano M, Tejerizo G, et al. Conjugal properties of the Sinorhizobium meliloti plasmid mobilome. FEMS Microbiol Ecol. 2008;65:372-82 pubmed publisher
    ..the conjugal properties of the cryptic plasmids present in a collection of the N(2)-fixing legume-symbiont Sinorhizobium meliloti. The study was performed on 65 S...
  2. Santos M, Cosme A, Becker J, Medeiros J, Mata M, Moreira L. Absence of functional TolC protein causes increased stress response gene expression in Sinorhizobium meliloti. BMC Microbiol. 2010;10:180 pubmed publisher
    The TolC protein from Sinorhizobium meliloti has previously been demonstrated to be required for establishing successful biological nitrogen fixation symbiosis with Medicago sativa...
  3. Imperlini E, Bianco C, Lonardo E, Camerini S, Cermola M, Moschetti G, et al. Effects of indole-3-acetic acid on Sinorhizobium meliloti survival and on symbiotic nitrogen fixation and stem dry weight production. Appl Microbiol Biotechnol. 2009;83:727-38 pubmed publisher
    ..the effects of the main auxin phytohormone, indole-3-acetic acid (IAA), on the central metabolism of Sinorhizobium meliloti 1021. We either treated S. meliloti 1021 wild-type cells with 0...
  4. Arnold M, Haag A, Capewell S, Boshoff H, James E, McDonald R, et al. Partial complementation of Sinorhizobium meliloti bacA mutant phenotypes by the Mycobacterium tuberculosis BacA protein. J Bacteriol. 2013;195:389-98 pubmed publisher
    The Sinorhizobium meliloti BacA ABC transporter protein plays an important role in its nodulating symbiosis with the legume alfalfa (Medicago sativa)...
  5. Rodriguez Llorente I, Caviedes M, Dary M, Palomares A, Canovas F, Peregrin Alvarez J. The Symbiosis Interactome: a computational approach reveals novel components, functional interactions and modules in Sinorhizobium meliloti. BMC Syst Biol. 2009;3:63 pubmed publisher
    ..address the complex dynamic interactions between proteins involved in the symbiosis of the model bacteria Sinorhizobium meliloti with its plant hosts...
  6. Wang C, Sheng X, Equi R, Trainer M, Charles T, Sobral B. Influence of the poly-3-hydroxybutyrate (PHB) granule-associated proteins (PhaP1 and PhaP2) on PHB accumulation and symbiotic nitrogen fixation in Sinorhizobium meliloti Rm1021. J Bacteriol. 2007;189:9050-6 pubmed publisher
    b>Sinorhizobium meliloti cells store excess carbon as intracellular poly-3-hydroxybutyrate (PHB) granules that assist survival under fluctuating nutritional conditions...
  7. Geddes B, Pickering B, Poysti N, Collins H, Yudistira H, Oresnik I. A locus necessary for the transport and catabolism of erythritol in Sinorhizobium meliloti. Microbiology. 2010;156:2970-81 pubmed publisher
    In this work we have genetically defined an erythritol utilization locus in Sinorhizobium meliloti. A cosmid containing the locus was isolated by complementation of a transposon mutant and was subsequently mutagenized using Tn5?:?:?B20...
  8. Vences Guzmán M, Geiger O, Sohlenkamp C. Sinorhizobium meliloti mutants deficient in phosphatidylserine decarboxylase accumulate phosphatidylserine and are strongly affected during symbiosis with alfalfa. J Bacteriol. 2008;190:6846-56 pubmed publisher
    b>Sinorhizobium meliloti contains phosphatidylglycerol, cardiolipin, phosphatidylcholine, and phosphatidylethanolamine (PE) as major membrane lipids. PE is formed in two steps...
  9. Geddes B, Oresnik I. Inability to catabolize galactose leads to increased ability to compete for nodule occupancy in Sinorhizobium meliloti. J Bacteriol. 2012;194:5044-53 pubmed publisher
    A mutant unable to utilize galactose was isolated in Sinorhizobium meliloti strain Rm1021. The mutation was found to be in a gene annotated dgoK1, a putative 2-keto-3-deoxygalactonokinase...
  10. Xu J, Li X, Luo L. Effects of engineered Sinorhizobium meliloti on cytokinin synthesis and tolerance of alfalfa to extreme drought stress. Appl Environ Microbiol. 2012;78:8056-61 pubmed publisher
    ..These findings suggest that engineered Sinorhizobium strains synthesizing more cytokinin could improve the tolerance of alfalfa to severe drought stress without affecting alfalfa nodulation or nitrogen fixation. ..

Detail Information

Publications165 found, 100 shown here

  1. Pistorio M, Giusti M, Del Papa M, Draghi W, Lozano M, Tejerizo G, et al. Conjugal properties of the Sinorhizobium meliloti plasmid mobilome. FEMS Microbiol Ecol. 2008;65:372-82 pubmed publisher
    ..the conjugal properties of the cryptic plasmids present in a collection of the N(2)-fixing legume-symbiont Sinorhizobium meliloti. The study was performed on 65 S...
  2. Santos M, Cosme A, Becker J, Medeiros J, Mata M, Moreira L. Absence of functional TolC protein causes increased stress response gene expression in Sinorhizobium meliloti. BMC Microbiol. 2010;10:180 pubmed publisher
    The TolC protein from Sinorhizobium meliloti has previously been demonstrated to be required for establishing successful biological nitrogen fixation symbiosis with Medicago sativa...
  3. Imperlini E, Bianco C, Lonardo E, Camerini S, Cermola M, Moschetti G, et al. Effects of indole-3-acetic acid on Sinorhizobium meliloti survival and on symbiotic nitrogen fixation and stem dry weight production. Appl Microbiol Biotechnol. 2009;83:727-38 pubmed publisher
    ..the effects of the main auxin phytohormone, indole-3-acetic acid (IAA), on the central metabolism of Sinorhizobium meliloti 1021. We either treated S. meliloti 1021 wild-type cells with 0...
  4. Arnold M, Haag A, Capewell S, Boshoff H, James E, McDonald R, et al. Partial complementation of Sinorhizobium meliloti bacA mutant phenotypes by the Mycobacterium tuberculosis BacA protein. J Bacteriol. 2013;195:389-98 pubmed publisher
    The Sinorhizobium meliloti BacA ABC transporter protein plays an important role in its nodulating symbiosis with the legume alfalfa (Medicago sativa)...
  5. Rodriguez Llorente I, Caviedes M, Dary M, Palomares A, Canovas F, Peregrin Alvarez J. The Symbiosis Interactome: a computational approach reveals novel components, functional interactions and modules in Sinorhizobium meliloti. BMC Syst Biol. 2009;3:63 pubmed publisher
    ..address the complex dynamic interactions between proteins involved in the symbiosis of the model bacteria Sinorhizobium meliloti with its plant hosts...
  6. Wang C, Sheng X, Equi R, Trainer M, Charles T, Sobral B. Influence of the poly-3-hydroxybutyrate (PHB) granule-associated proteins (PhaP1 and PhaP2) on PHB accumulation and symbiotic nitrogen fixation in Sinorhizobium meliloti Rm1021. J Bacteriol. 2007;189:9050-6 pubmed publisher
    b>Sinorhizobium meliloti cells store excess carbon as intracellular poly-3-hydroxybutyrate (PHB) granules that assist survival under fluctuating nutritional conditions...
  7. Geddes B, Pickering B, Poysti N, Collins H, Yudistira H, Oresnik I. A locus necessary for the transport and catabolism of erythritol in Sinorhizobium meliloti. Microbiology. 2010;156:2970-81 pubmed publisher
    In this work we have genetically defined an erythritol utilization locus in Sinorhizobium meliloti. A cosmid containing the locus was isolated by complementation of a transposon mutant and was subsequently mutagenized using Tn5?:?:?B20...
  8. Vences Guzmán M, Geiger O, Sohlenkamp C. Sinorhizobium meliloti mutants deficient in phosphatidylserine decarboxylase accumulate phosphatidylserine and are strongly affected during symbiosis with alfalfa. J Bacteriol. 2008;190:6846-56 pubmed publisher
    b>Sinorhizobium meliloti contains phosphatidylglycerol, cardiolipin, phosphatidylcholine, and phosphatidylethanolamine (PE) as major membrane lipids. PE is formed in two steps...
  9. Geddes B, Oresnik I. Inability to catabolize galactose leads to increased ability to compete for nodule occupancy in Sinorhizobium meliloti. J Bacteriol. 2012;194:5044-53 pubmed publisher
    A mutant unable to utilize galactose was isolated in Sinorhizobium meliloti strain Rm1021. The mutation was found to be in a gene annotated dgoK1, a putative 2-keto-3-deoxygalactonokinase...
  10. Xu J, Li X, Luo L. Effects of engineered Sinorhizobium meliloti on cytokinin synthesis and tolerance of alfalfa to extreme drought stress. Appl Environ Microbiol. 2012;78:8056-61 pubmed publisher
    ..These findings suggest that engineered Sinorhizobium strains synthesizing more cytokinin could improve the tolerance of alfalfa to severe drought stress without affecting alfalfa nodulation or nitrogen fixation. ..
  11. Trainer M, Capstick D, Zachertowska A, Lam K, Clark S, Charles T. Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti. BMC Microbiol. 2010;10:92 pubmed publisher
    ..The reduced survival capacity of free-living cells unable to access their accumulated stores of PHB suggests that PHB is a crucial metabolite under adverse conditions...
  12. Bélanger L, Charles T. Members of the Sinorhizobium meliloti ChvI regulon identified by a DNA binding screen. BMC Microbiol. 2013;13:132 pubmed publisher
    The Sinorhizobium meliloti ExoS/ChvI two component regulatory system is required for N2-fixing symbiosis and exopolysaccharide synthesis...
  13. MacLean A, Haerty W, Golding G, Finan T. The LysR-type PcaQ protein regulates expression of a protocatechuate-inducible ABC-type transport system in Sinorhizobium meliloti. Microbiology. 2011;157:2522-33 pubmed publisher
    ..and we have previously defined a PcaQ DNA-binding site located upstream of the target pcaDCHGB operon in Sinorhizobium meliloti. In this work, we show that PcaQ also regulates the expression of the S...
  14. Queiroux C, Washburn B, Davis O, Stewart J, Brewer T, Lyons M, et al. A comparative genomics screen identifies a Sinorhizobium meliloti 1021 sodM-like gene strongly expressed within host plant nodules. BMC Microbiol. 2012;12:74 pubmed publisher
  15. Wilson J, Kappler U. Sulfite oxidation in Sinorhizobium meliloti. Biochim Biophys Acta. 2009;1787:1516-25 pubmed publisher
    ..However, little is known about SOE diversity and metabolic roles. Sinorhizobium meliloti contains four candidate genes encoding SOEs of three different types, and in this work we have ..
  16. Sanz Sáez A, Erice G, Aguirreolea J, Munoz F, Sanchez Diaz M, Irigoyen J. Alfalfa forage digestibility, quality and yield under future climate change scenarios vary with Sinorhizobium meliloti strain. J Plant Physiol. 2012;169:782-8 pubmed publisher
    ..The aim of the present study was to analyse the effect of elevated CO(2), elevated temperature and Sinorhizobium meliloti strains (102F78, 102F34 and 1032 GMI) on alfalfa yield, forage quality and in vitro dry matter ..
  17. Schlüter J, Reinkensmeier J, Daschkey S, Evguenieva Hackenberg E, Janssen S, Jänicke S, et al. A genome-wide survey of sRNAs in the symbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti. BMC Genomics. 2010;11:245 pubmed publisher
    ..study reports on a comprehensive screen for sRNAs in the symbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti applying deep sequencing of cDNAs and microarray hybridizations...
  18. Blanca Ordóñez H, Oliva García J, Pérez Mendoza D, Soto M, Olivares J, Sanjuan J, et al. pSymA-dependent mobilization of the Sinorhizobium meliloti pSymB megaplasmid. J Bacteriol. 2010;192:6309-12 pubmed publisher
    b>Sinorhizobium meliloti 1021 carries two megaplasmids, pSymA of 1,354 kb and pSymB of 1,683 kb, which are essential in establishing symbiosis with its legume hosts and important for bacterial fitness in the rhizosphere...
  19. Jones K, Lloret J, Daniele J, Walker G. The type IV secretion system of Sinorhizobium meliloti strain 1021 is required for conjugation but not for intracellular symbiosis. J Bacteriol. 2007;189:2133-8 pubmed
    The type IV secretion system (T4SS) of the plant intracellular symbiont Sinorhizobium meliloti 1021 is required for conjugal transfer of DNA...
  20. Bianco C, Defez R. Improvement of phosphate solubilization and Medicago plant yield by an indole-3-acetic acid-overproducing strain of Sinorhizobium meliloti. Appl Environ Microbiol. 2010;76:4626-32 pubmed publisher
    ..It has been published that the RD64 strain, a Sinorhizobium meliloti 1021 strain engineered to overproduce indole-3-acetic acid (IAA), showed improved nitrogen fixation ..
  21. Torres M, Rubia M, Bedmar E, Delgado M. Denitrification in Sinorhizobium meliloti. Biochem Soc Trans. 2011;39:1886-9 pubmed publisher
    ..homology with nap, nirK, nor and nos genes have been found in the genome of the symbiotic plasmid pSymA of Sinorhizobium meliloti strain 1021. Whole-genome transcriptomic analyses have demonstrated that S...
  22. Sallet E, Roux B, Sauviac L, Jardinaud M, Carrère S, Faraut T, et al. Next-generation annotation of prokaryotic genomes with EuGene-P: application to Sinorhizobium meliloti 2011. DNA Res. 2013;20:339-54 pubmed publisher
    ..EuGene-P was used to comprehensively and accurately annotate the genome of the nitrogen-fixing bacterium Sinorhizobium meliloti strain 2011, leading to the prediction of 6308 CDSs as well as 1876 ncRNAs...
  23. de las Nieves Peltzer M, Roques N, Poinsot V, Aguilar O, Batut J, Capela D. Auxotrophy accounts for nodulation defect of most Sinorhizobium meliloti mutants in the branched-chain amino acid biosynthesis pathway. Mol Plant Microbe Interact. 2008;21:1232-41 pubmed publisher
    Some Sinorhizobium meliloti mutants in genes involved in isoleucine, valine, and leucine biosynthesis were previously described as being unable to induce nodule formation on host plants...
  24. Barnett M, Bittner A, Toman C, Oke V, Long S. Dual RpoH sigma factors and transcriptional plasticity in a symbiotic bacterium. J Bacteriol. 2012;194:4983-94 pubmed publisher
    b>Sinorhizobium meliloti can live as a soil saprophyte and can engage in a nitrogen-fixing symbiosis with plant roots. To succeed in such diverse environments, the bacteria must continually adjust gene expression...
  25. Zurdo Piñeiro J, García Fraile P, Rivas R, Peix A, León Barrios M, Willems A, et al. Rhizobia from Lanzarote, the Canary Islands, that nodulate Phaseolus vulgaris have characteristics in common with Sinorhizobium meliloti isolates from mainland Spain. Appl Environ Microbiol. 2009;75:2354-9 pubmed publisher
    ..soil of Lanzarote, an island of the Canary Islands, were identical to a less-common pattern found within Sinorhizobium meliloti (assigned to group II) obtained from nodules of alfalfa and alfalfa-related legumes grown in northern ..
  26. Poysti N, Oresnik I. Characterization of Sinorhizobium meliloti triose phosphate isomerase genes. J Bacteriol. 2007;189:3445-51 pubmed
    A Tn5 mutant strain of Sinorhizobium meliloti with an insertion in tpiA (systematic identifier SMc01023), a putative triose phosphate isomerase (TPI)-encoding gene, was isolated...
  27. Pucciariello C, Innocenti G, Van de Velde W, Lambert A, Hopkins J, Clement M, et al. (Homo)glutathione depletion modulates host gene expression during the symbiotic interaction between Medicago truncatula and Sinorhizobium meliloti. Plant Physiol. 2009;151:1186-96 pubmed publisher
    ..truncatula. In this study, the plant transcriptomic response to Sinorhizobium meliloti infection under (h)GSH depletion was investigated using cDNA-amplified fragment length polymorphism ..
  28. Nogales J, Bernabéu Roda L, Cuéllar V, Soto M. ExpR is not required for swarming but promotes sliding in Sinorhizobium meliloti. J Bacteriol. 2012;194:2027-35 pubmed publisher
    ..It has been reported that the swarming ability of the soil bacterium Sinorhizobium meliloti Rm2011 requires a functional ExpR/Sin quorum-sensing system...
  29. Pini F, Frage B, Ferri L, De Nisco N, Mohapatra S, Taddei L, et al. The DivJ, CbrA and PleC system controls DivK phosphorylation and symbiosis in Sinorhizobium meliloti. Mol Microbiol. 2013;90:54-71 pubmed publisher
    b>Sinorhizobium meliloti is a soil bacterium that invades the root nodules it induces on Medicago sativa, whereupon it undergoes an alteration of its cell cycle and differentiates into nitrogen-fixing, elongated and polyploid bacteroid with ..
  30. Lohar D, Haridas S, Gantt J, VandenBosch K. A transient decrease in reactive oxygen species in roots leads to root hair deformation in the legume-rhizobia symbiosis. New Phytol. 2007;173:39-49 pubmed
    ..The results suggest a role for the transient reduction of ROS accumulation in governing NF-induced root hair deformation in legumes. ..
  31. Smit P, Limpens E, Geurts R, Fedorova E, Dolgikh E, Gough C, et al. Medicago LYK3, an entry receptor in rhizobial nodulation factor signaling. Plant Physiol. 2007;145:183-91 pubmed
    ..Therefore, LYK3 functions as the proposed entry receptor, specifically controlling infection. Finally, we show that LYK3, which regulates a subset of Nod factor-induced genes, is not required for the induction of NODULE INCEPTION. ..
  32. Bahlawane C, Baumgarth B, Serrania J, Rüberg S, Becker A. Fine-tuning of galactoglucan biosynthesis in Sinorhizobium meliloti by differential WggR (ExpG)-, PhoB-, and MucR-dependent regulation of two promoters. J Bacteriol. 2008;190:3456-66 pubmed publisher
    Depending on the phosphate concentration encountered in the environment Sinorhizobium meliloti 2011 synthesizes two different exopolysaccharides (EPS)...
  33. Maruya J, Saeki K. The bacA gene homolog, mlr7400, in Mesorhizobium loti MAFF303099 is dispensable for symbiosis with Lotus japonicus but partially capable of supporting the symbiotic function of bacA in Sinorhizobium meliloti. Plant Cell Physiol. 2010;51:1443-52 pubmed publisher
    ..One such evasion-related genes is Sinorhizobium meliloti bacA that is essential for bacteroid formation...
  34. Ulvé V, Chéron A, Trautwetter A, Fontenelle C, Barloy Hubler F. Characterization and expression patterns of Sinorhizobium meliloti tmRNA (ssrA). FEMS Microbiol Lett. 2007;269:117-23 pubmed
    tmRNA (ssrA) in Sinorhizobium meliloti is a small RNA annotated by homology with the Bradyrhizobium japonicum sra molecule...
  35. Combier J, Vernié T, de Billy F, El Yahyaoui F, Mathis R, Gamas P. The MtMMPL1 early nodulin is a novel member of the matrix metalloendoproteinase family with a role in Medicago truncatula infection by Sinorhizobium meliloti. Plant Physiol. 2007;144:703-16 pubmed
    ..identified by transcriptomics, represents a novel and specific marker for root and nodule infection by Sinorhizobium meliloti. This was established by determining the spatial pattern of MtMMPL1 expression and evaluating gene ..
  36. Gu X, Lee S, Bar Peled M. Biosynthesis of UDP-xylose and UDP-arabinose in Sinorhizobium meliloti 1021: first characterization of a bacterial UDP-xylose synthase, and UDP-xylose 4-epimerase. Microbiology. 2011;157:260-9 pubmed publisher
    b>Sinorhizobium meliloti is a soil bacterium that fixes nitrogen after being established inside nodules that can form on the roots of several legumes, including Medicago truncatula. A mutation in an S...
  37. Gao M, Chen H, Eberhard A, Gronquist M, Robinson J, Connolly M, et al. Effects of AiiA-mediated quorum quenching in Sinorhizobium meliloti on quorum-sensing signals, proteome patterns, and symbiotic interactions. Mol Plant Microbe Interact. 2007;20:843-56 pubmed
    ..approach was used here to identify QS-regulated behaviors in the N-fixing bacterial symbiont Sinorhizobium meliloti. The AiiA lactonase from Bacillus produced in S. meliloti was shown to enzymatically inactivate S...
  38. Taga M, Walker G. Sinorhizobium meliloti requires a cobalamin-dependent ribonucleotide reductase for symbiosis with its plant host. Mol Plant Microbe Interact. 2010;23:1643-54 pubmed publisher
    ..We previously showed that the symbiotic nitrogen-fixing alphaproteobacterium Sinorhizobium meliloti requires cobalamin to establish a symbiotic relationship with its plant host, Medicago sativa (alfalfa)...
  39. Sauviac L, Philippe H, Phok K, Bruand C. An extracytoplasmic function sigma factor acts as a general stress response regulator in Sinorhizobium meliloti. J Bacteriol. 2007;189:4204-16 pubmed
    b>Sinorhizobium meliloti genes transcriptionally up-regulated after heat stress, as well as upon entry into stationary phase, were identified by microarray analyses...
  40. Simsek S, Ojanen Reuhs T, Stephens S, Reuhs B. Strain-ecotype specificity in Sinorhizobium meliloti-Medicago truncatula symbiosis is correlated to succinoglycan oligosaccharide structure. J Bacteriol. 2007;189:7733-40 pubmed
    ..are necessary for the establishment of nitrogen-fixing nodules (Fix+) in Medicago truncatula-Sinorhizobium meliloti symbiosis. This report shows that M. truncatula-S...
  41. Voss B, Hölscher M, Baumgarth B, Kalbfleisch A, Kaya C, Hess W, et al. Expression of small RNAs in Rhizobiales and protection of a small RNA and its degradation products by Hfq in Sinorhizobium meliloti. Biochem Biophys Res Commun. 2009;390:331-6 pubmed publisher
    ..Here, five small RNAs were studied in Sinorhizobium meliloti - SmrC15, SmrC16, Sra33, 6S and the signal recognition particle (SRP) RNA, which are conserved among at ..
  42. Nogales J, Domínguez Ferreras A, Amaya Gómez C, van Dillewijn P, Cuéllar V, Sanjuan J, et al. Transcriptome profiling of a Sinorhizobium meliloti fadD mutant reveals the role of rhizobactin 1021 biosynthesis and regulation genes in the control of swarming. BMC Genomics. 2010;11:157 pubmed publisher
    ..In Sinorhizobium meliloti this type of motility has been described in a fadD mutant...
  43. Sobrero P, Valverde C. Evidences of autoregulation of hfq expression in Sinorhizobium meliloti strain 2011. Arch Microbiol. 2011;193:629-39 pubmed publisher
    ..In the ?-proteobacterium Sinorhizobium meliloti, the large number of detected small RNA transcripts and the pleiotropic effects of hfq mutations lead to ..
  44. Diaz R, Vargas Lagunas C, Villalobos M, Peralta H, Mora Y, Encarnación S, et al. argC Orthologs from Rhizobiales show diverse profiles of transcriptional efficiency and functionality in Sinorhizobium meliloti. J Bacteriol. 2011;193:460-72 pubmed publisher
    ..the transcriptional expression and metabolic performance of ortholog substitution complementing a Sinorhizobium meliloti argC mutant with argC from Rhizobiales (Agrobacterium tumefaciens, Rhizobium etli, and Mesorhizobium loti)...
  45. Tu C, Teng Y, Luo Y, Li X, Sun X, Li Z, et al. Potential for biodegradation of polychlorinated biphenyls (PCBs) by Sinorhizobium meliloti. J Hazard Mater. 2011;186:1438-44 pubmed publisher
    ..capability and metabolic intermediate of polychlorinated biphenyls (PCBs) by a rhizobial strain Sinorhizobium meliloti. Biodegradation was observed immediately after 2,4,4'-TCB was supplied as a sole source of carbon and ..
  46. Fontenelle C, Blanco C, Arrieta M, Dufour V, Trautwetter A. Resistance to organic hydroperoxides requires ohr and ohrR genes in Sinorhizobium meliloti. BMC Microbiol. 2011;11:100 pubmed publisher
    b>Sinorhizobium meliloti is a symbiotic nitrogen-fixing bacterium that elicits nodules on roots of host plants Medicago sativa. During nodule formation bacteria have to withstand oxygen radicals produced by the plant...
  47. Pauly N, Ferrari C, Andrio E, Marino D, Piardi S, Brouquisse R, et al. MtNOA1/RIF1 modulates Medicago truncatula-Sinorhizobium meliloti nodule development without affecting its nitric oxide content. J Exp Bot. 2011;62:939-48 pubmed publisher
    ..of an AtNoa1/Rif1 orthologue from Medicago truncatula (MtNoa1/Rif1) during its symbiotic interaction with Sinorhizobium meliloti has been studied...
  48. Mao C, Evans C, Jensen R, Sobral B. Identification of new genes in Sinorhizobium meliloti using the Genome Sequencer FLX system. BMC Microbiol. 2008;8:72 pubmed publisher
    b>Sinorhizobium meliloti is an agriculturally important model symbiont. There is an ongoing need to update and improve its genome annotation...
  49. MacLean A, White C, Fowler J, Finan T. Identification of a hydroxyproline transport system in the legume endosymbiont Sinorhizobium meliloti. Mol Plant Microbe Interact. 2009;22:1116-27 pubmed publisher
    ..an ABC-type transport system dedicated to the uptake of hydroxyproline in the legume endosymbiont Sinorhizobium meliloti. We have designated genes involved in hydroxyproline metabolism as hyp genes and show that an S...
  50. Laporte P, Satiat Jeunemaitre B, Velasco I, Csorba T, Van de Velde W, Campalans A, et al. A novel RNA-binding peptide regulates the establishment of the Medicago truncatula-Sinorhizobium meliloti nitrogen-fixing symbiosis. Plant J. 2010;62:24-38 pubmed publisher
    ..MtSNARP2 RNA interference (RNAi) transgenic roots showed aberrant early senescent nodules where differentiated bacteroids degenerate rapidly. Hence, a functional symbiotic interaction may be regulated by secreted RNA-binding peptides. ..
  51. Deák V, Lukacs R, Buzás Z, Pálvölgyi A, Papp P, Orosz L, et al. Identification of tail genes in the temperate phage 16-3 of Sinorhizobium meliloti 41. J Bacteriol. 2010;192:1617-23 pubmed publisher
    Genes encoding the tail proteins of the temperate phage 16-3 of the symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti 41 have been identified...
  52. Ye H, Gemperline E, Venkateshwaran M, Chen R, Delaux P, Howes Podoll M, et al. MALDI mass spectrometry-assisted molecular imaging of metabolites during nitrogen fixation in the Medicago truncatula-Sinorhizobium meliloti symbiosis. Plant J. 2013;75:130-145 pubmed publisher
    ..The Medicago truncatula-Sinorhizobium meliloti association is an excellent model for dissecting this nitrogen-fixing symbiosis because of the ..
  53. Mueller K, Gonz lez J. Complex regulation of symbiotic functions is coordinated by MucR and quorum sensing in Sinorhizobium meliloti. J Bacteriol. 2011;193:485-96 pubmed publisher
    In Sinorhizobium meliloti, the production of exopolysaccharides such as succinoglycan and exopolysaccharide II (EPS II) enables the bacterium to invade root nodules on Medicago sativa and establish a nitrogen-fixing symbiosis...
  54. Liu W, Kohlen W, Lillo A, Op den Camp R, Ivanov S, Hartog M, et al. Strigolactone biosynthesis in Medicago truncatula and rice requires the symbiotic GRAS-type transcription factors NSP1 and NSP2. Plant Cell. 2011;23:3853-65 pubmed publisher
    ..NSP1 and NSP2 are single-copy genes in legumes, which implies that both proteins fulfill dual regulatory functions to control downstream targets after rhizobium-induced signaling as well as SL biosynthesis in nonsymbiotic conditions...
  55. Haag A, Wehmeier S, Muszynski A, Kerscher B, Fletcher V, Berry S, et al. Biochemical characterization of Sinorhizobium meliloti mutants reveals gene products involved in the biosynthesis of the unusual lipid A very long-chain fatty acid. J Biol Chem. 2011;286:17455-66 pubmed publisher
    b>Sinorhizobium meliloti forms a symbiosis with the legume alfalfa, whereby it differentiates into a nitrogen-fixing bacteroid. The lipid A species of S...
  56. Sorroche F, Spesia M, Zorreguieta A, Giordano W. A positive correlation between bacterial autoaggregation and biofilm formation in native Sinorhizobium meliloti isolates from Argentina. Appl Environ Microbiol. 2012;78:4092-101 pubmed publisher
    b>Sinorhizobium meliloti is a symbiotic nitrogen-fixing bacterium that elicits nodule formation on roots of alfalfa plants. S. meliloti produces two exopolysaccharides (EPSs), termed EPS I and EPS II, that are both able to promote symbiosis...
  57. Pii Y, Crimi M, Cremonese G, Spena A, Pandolfini T. Auxin and nitric oxide control indeterminate nodule formation. BMC Plant Biol. 2007;7:21 pubmed
    ..We have addressed the effects of bacterial auxin (IAA) on nodulation by using Sinorhizobium meliloti and Rhizobium leguminosarum bacteria genetically engineered for increased auxin synthesis...
  58. Tian C, Garnerone A, Mathieu Demazière C, Masson Boivin C, Batut J. Plant-activated bacterial receptor adenylate cyclases modulate epidermal infection in the Sinorhizobium meliloti-Medicago symbiosis. Proc Natl Acad Sci U S A. 2012;109:6751-6 pubmed publisher
    ..Here we identify in Sinorhizobium meliloti, the Medicago symbiont, a cAMP-signaling regulatory cascade consisting of three receptor-like adenylate ..
  59. Kuhn S, Stiens M, Pühler A, Schluter A. Prevalence of pSmeSM11a-like plasmids in indigenous Sinorhizobium meliloti strains isolated in the course of a field release experiment with genetically modified S. meliloti strains. FEMS Microbiol Ecol. 2008;63:118-31 pubmed
    Plasmid pSmeSM11a, residing in the indigenous Sinorhizobium meliloti strain SM11 originating from a field in Strassmoos (Bavaria, Germany), was analysed previously at the genomic level. Thirty-seven indigenous S...
  60. Lefebvre B, Timmers T, Mbengue M, Moreau S, Herve C, Toth K, et al. A remorin protein interacts with symbiotic receptors and regulates bacterial infection. Proc Natl Acad Sci U S A. 2010;107:2343-8 pubmed publisher
    ..We used root nodule symbiosis between Medicago truncatula and Sinorhizobium meliloti to study the roles of a remorin that is specifically induced during nodulation...
  61. Rinaudi L, Sorroche F, Zorreguieta A, Giordano W. Analysis of the mucR gene regulating biosynthesis of exopolysaccharides: implications for biofilm formation in Sinorhizobium meliloti Rm1021. FEMS Microbiol Lett. 2010;302:15-21 pubmed publisher
    ..In Sinorhizobium meliloti, the regulatory protein MucR controls exopolysaccharide production...
  62. Meilhoc E, Cam Y, Skapski A, Bruand C. The response to nitric oxide of the nitrogen-fixing symbiont Sinorhizobium meliloti. Mol Plant Microbe Interact. 2010;23:748-59 pubmed publisher
    ..of NO during the symbiotic interaction between the model legume Medicago truncatula and its symbiont Sinorhizobium meliloti have been reported but the role of NO in symbiosis is far from being elucidated...
  63. Jones K, Sharopova N, Lohar D, Zhang J, VandenBosch K, Walker G. Differential response of the plant Medicago truncatula to its symbiont Sinorhizobium meliloti or an exopolysaccharide-deficient mutant. Proc Natl Acad Sci U S A. 2008;105:704-9 pubmed publisher
    b>Sinorhizobium meliloti forms symbiotic, nitrogen-fixing nodules on the roots of Medicago truncatula. The bacteria invade and colonize the roots through structures called infection threads. S...
  64. Bittner A, Foltz A, Oke V. Only one of five groEL genes is required for viability and successful symbiosis in Sinorhizobium meliloti. J Bacteriol. 2007;189:1884-9 pubmed
    ..In particular, in Sinorhizobium meliloti there are four groESL operons and one groEL gene...
  65. Wells D, Chen E, Fisher R, Long S. ExoR is genetically coupled to the ExoS-ChvI two-component system and located in the periplasm of Sinorhizobium meliloti. Mol Microbiol. 2007;64:647-64 pubmed
    b>Sinorhizobium meliloti enters into a symbiotic relationship with legume host plants, providing fixed nitrogen in exchange for carbon and amino acids. In S...
  66. Horchani F, Pr vot M, Boscari A, Evangelisti E, Meilhoc E, Bruand C, et al. Both plant and bacterial nitrate reductases contribute to nitric oxide production in Medicago truncatula nitrogen-fixing nodules. Plant Physiol. 2011;155:1023-36 pubmed publisher
    ..truncatula-Sinorhizobium meliloti nodules under normoxic and hypoxic conditions...
  67. Schneiker Bekel S, Wibberg D, Bekel T, Blom J, Linke B, Neuweger H, et al. The complete genome sequence of the dominant Sinorhizobium meliloti field isolate SM11 extends the S. meliloti pan-genome. J Biotechnol. 2011;155:20-33 pubmed publisher
    Isolates of the symbiotic nitrogen-fixing species Sinorhizobium meliloti usually contain a chromosome and two large megaplasmids encoding functions that are absolutely required for the specific interaction of the microsymbiont with ..
  68. Schlüter J, Reinkensmeier J, Barnett M, Lang C, Krol E, Giegerich R, et al. Global mapping of transcription start sites and promoter motifs in the symbiotic ?-proteobacterium Sinorhizobium meliloti 1021. BMC Genomics. 2013;14:156 pubmed publisher
    b>Sinorhizobium meliloti is a soil-dwelling ?-proteobacterium that possesses a large, tripartite genome and engages in a nitrogen fixing symbiosis with its plant hosts...
  69. Rossbach S, Mai D, Carter E, Sauviac L, Capela D, Bruand C, et al. Response of Sinorhizobium meliloti to elevated concentrations of cadmium and zinc. Appl Environ Microbiol. 2008;74:4218-21 pubmed publisher
    Whole-genome transcriptional profiling was used to identify genes in Sinorhizobium meliloti 1021 that are differentially expressed during exposure to elevated concentrations of cadmium and zinc...
  70. Ratcliff W, Denison R. Individual-level bet hedging in the bacterium Sinorhizobium meliloti. Curr Biol. 2010;20:1740-4 pubmed publisher
    ..b>Sinorhizobium meliloti stores carbon and energy in poly-3-hydroxybutyrate (PHB) as a contingency against carbon scarcity...
  71. Moreau S, Verdenaud M, Ott T, Letort S, de Billy F, Niebel A, et al. Transcription reprogramming during root nodule development in Medicago truncatula. PLoS ONE. 2011;6:e16463 pubmed publisher
    ..have been used to study the transcriptome of root nodules induced by either wild type or mutant strains of Sinorhizobium meliloti. In this way we have defined eight major activation patterns in nodules and identified associated ..
  72. Del Giudice J, Cam Y, Damiani I, Fung Chat F, Meilhoc E, Bruand C, et al. Nitric oxide is required for an optimal establishment of the Medicago truncatula-Sinorhizobium meliloti symbiosis. New Phytol. 2011;191:405-17 pubmed publisher
    ..we detected NO production in the first steps, during infection threads growth, of the Medicago truncatula-Sinorhizobium meliloti symbiotic interaction. Nitric oxide was also detected, by confocal microscopy, in nodule primordia...
  73. Cheng J, Poduska B, Morton R, Finan T. An ABC-type cobalt transport system is essential for growth of Sinorhizobium meliloti at trace metal concentrations. J Bacteriol. 2011;193:4405-16 pubmed publisher
    We report expression and mutant phenotypes for a gene cluster in Sinorhizobium meliloti, designated cbtJKL, that has been shown to encode an ABC-type cobalt transport system...
  74. van Noorden G, Kerim T, Goffard N, Wiblin R, Pellerone F, Rolfe B, et al. Overlap of proteome changes in Medicago truncatula in response to auxin and Sinorhizobium meliloti. Plant Physiol. 2007;144:1115-31 pubmed
    ..mass spectrometry to compare proteomes of wild-type and sunn mutant roots after 24 h of treatment with Sinorhizobium meliloti, auxin, or a control. We identified 131 of 270 proteins responding to treatment with S...
  75. Larrainzar E, Wienkoop S, Weckwerth W, Ladrera R, Arrese Igor C, Gonzalez E. Medicago truncatula root nodule proteome analysis reveals differential plant and bacteroid responses to drought stress. Plant Physiol. 2007;144:1495-507 pubmed
    ..Drought was imposed on Medicago truncatula 'Jemalong A17' plants grown in symbiosis with Sinorhizobium meliloti strain 2011...
  76. Flechard M, Fontenelle C, Trautwetter A, Ermel G, Blanco C. Sinorhizobium meliloti rpoE2 is necessary for H(2)O(2) stress resistance during the stationary growth phase. FEMS Microbiol Lett. 2009;290:25-31 pubmed publisher
    RpoE2 is an extracytoplasmic sigma factor produced by Sinorhizobium meliloti during stationary growth phase. Its inactivation affected the synthesis of the superoxide dismutase, SodC, and catalase, KatC...
  77. Zaheer R, Morton R, Proudfoot M, Yakunin A, Finan T. Genetic and biochemical properties of an alkaline phosphatase PhoX family protein found in many bacteria. Environ Microbiol. 2009;11:1572-87 pubmed publisher
    ..and genetic regulation of PhoX, the major alkaline phosphatase protein from the soil bacterium Sinorhizobium meliloti. The protein is shown to be a member of a recently identified family of PhoX alkaline phosphatase proteins ..
  78. Haag A, Wehmeier S, Beck S, Marlow V, Fletcher V, James E, et al. The Sinorhizobium meliloti LpxXL and AcpXL proteins play important roles in bacteroid development within alfalfa. J Bacteriol. 2009;191:4681-6 pubmed publisher
    Free-living Sinorhizobium meliloti lpxXL and acpXL mutants lack lipid A very-long-chain fatty acids (VLCFAs) and have reduced competitiveness in alfalfa...
  79. Bastiat B, Sauviac L, Bruand C. Dual control of Sinorhizobium meliloti RpoE2 sigma factor activity by two PhyR-type two-component response regulators. J Bacteriol. 2010;192:2255-65 pubmed publisher
    RpoE2 is an extracytoplasmic function (ECF) sigma factor involved in the general stress response of Sinorhizobium meliloti, the nitrogen-fixing symbiont of the legume plant alfalfa...
  80. Carlyon R, Ryther J, VanYperen R, Griffitts J. FeuN, a novel modulator of two-component signalling identified in Sinorhizobium meliloti. Mol Microbiol. 2010;77:170-82 pubmed publisher
    b>Sinorhizobium meliloti is a nitrogen-fixing bacterial symbiont of alfalfa and related legumes. Symbiotic infection by S...
  81. Stiens M, Schneiker S, Pühler A, Schluter A. Sequence analysis of the 181-kb accessory plasmid pSmeSM11b, isolated from a dominant Sinorhizobium meliloti strain identified during a long-term field release experiment. FEMS Microbiol Lett. 2007;271:297-309 pubmed
    The 181 251 bp accessory plasmid pSmeSM11b of Sinorhizobium meliloti strain SM11, belonging to a dominant indigenous S. meliloti subpopulation identified during a long-term field release experiment, was sequenced...
  82. Humann J, Schroeder B, Mortimer M, House B, Yurgel S, Maloney S, et al. Construction and expression of sugar kinase transcriptional gene fusions by using the Sinorhizobium meliloti ORFeome. Appl Environ Microbiol. 2008;74:6756-65 pubmed publisher
    The Sinorhizobium meliloti ORFeome project cloned 6,314 open reading frames (ORFs) into a modified Gateway entry vector system from which the ORFs could be transferred to destination vectors in vivo via bacterial conjugation...
  83. Patankar A, GONZALEZ J. An orphan LuxR homolog of Sinorhizobium meliloti affects stress adaptation and competition for nodulation. Appl Environ Microbiol. 2009;75:946-55 pubmed publisher
    The Sin/ExpR quorum-sensing system of Sinorhizobium meliloti plays an important role in the symbiotic association with its host plant, Medicago sativa...
  84. Epstein B, Branca A, Mudge J, Bharti A, Briskine R, Farmer A, et al. Population genomics of the facultatively mutualistic bacteria Sinorhizobium meliloti and S. medicae. PLoS Genet. 2012;8:e1002868 pubmed publisher
    ..Based upon available functional information, several genes identified as targets of selection are likely to alter the symbiosis with the host plant, making them attractive targets for further functional characterization...
  85. Naya L, Ladrera R, Ramos J, Gonzalez E, Arrese Igor C, Minchin F, et al. The response of carbon metabolism and antioxidant defenses of alfalfa nodules to drought stress and to the subsequent recovery of plants. Plant Physiol. 2007;144:1104-14 pubmed
    ..We conclude that a limitation in metabolic capacity of bacteroids and oxidative damage of cellular components are contributing factors to the inhibition of N(2)ase activity in alfalfa nodules. ..
  86. Sevin E, Barloy Hubler F. RASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotes. Genome Biol. 2007;8:R155 pubmed
    ..The tool successfully confirmed all reported TA systems, and spotted new putative loci upon screening of sequenced genomes. RASTA-Bacteria is publicly available at http://genoweb.univ-rennes1.fr/duals/RASTA-Bacteria. ..
  87. Hoang H, Gurich N, GONZALEZ J. Regulation of motility by the ExpR/Sin quorum-sensing system in Sinorhizobium meliloti. J Bacteriol. 2008;190:861-71 pubmed
    A successful symbiotic relationship between Sinorhizobium meliloti and its host Medicago sativa (alfalfa) depends on several signaling mechanisms, such as the biosynthesis of exopolysaccharides (EPS) by S. meliloti...
  88. Fujishige N, Lum M, De Hoff P, Whitelegge J, Faull K, Hirsch A. Rhizobium common nod genes are required for biofilm formation. Mol Microbiol. 2008;67:504-15 pubmed
    ..oligomer, are also required for the establishment of the three-dimensional architecture of the biofilm of Sinorhizobium meliloti. Common nod gene mutants form a biofilm that is a monolayer. Moreover, adding Nod Factor antibody to S...
  89. Marlow V, Haag A, Kobayashi H, Fletcher V, Scocchi M, Walker G, et al. Essential role for the BacA protein in the uptake of a truncated eukaryotic peptide in Sinorhizobium meliloti. J Bacteriol. 2009;191:1519-27 pubmed publisher
    The inner membrane BacA protein is essential for the establishment of chronic intracellular infections by Sinorhizobium meliloti and Brucella abortus within plant and mammalian hosts, respectively. In their free-living state, S...
  90. Koziol U, Hannibal L, Rodr guez M, Fabiano E, Kahn M, Noya F. Deletion of citrate synthase restores growth of Sinorhizobium meliloti 1021 aconitase mutants. J Bacteriol. 2009;191:7581-6 pubmed publisher
    The symbiotic nitrogen-fixing bacterium Sinorhizobium meliloti 1021 encodes only one predicted aconitase (AcnA) in its genome...
  91. Maunoury N, Redondo Nieto M, Bourcy M, Van de Velde W, Alunni B, Laporte P, et al. Differentiation of symbiotic cells and endosymbionts in Medicago truncatula nodulation are coupled to two transcriptome-switches. PLoS ONE. 2010;5:e9519 pubmed publisher
    The legume plant Medicago truncatula establishes a symbiosis with the nitrogen-fixing bacterium Sinorhizobium meliloti which takes place in root nodules...
  92. Trabelsi D, Pini F, Aouani M, Bazzicalupo M, Mengoni A. Development of real-time PCR assay for detection and quantification of Sinorhizobium meliloti in soil and plant tissue. Lett Appl Microbiol. 2009;48:355-61 pubmed publisher
    b>Sinorhizobium meliloti is a nitrogen-fixing alpha-proteobacterium present in soil and symbiotically associated with root nodules of leguminous plants...
  93. McIntosh M, Meyer S, Becker A. Novel Sinorhizobium meliloti quorum sensing positive and negative regulatory feedback mechanisms respond to phosphate availability. Mol Microbiol. 2009;74:1238-56 pubmed publisher
    The Sin quorum sensing system of Sinorhizobium meliloti depends upon at least three genes, sinR, sinI and expR, and N-acyl homoserine lactones (AHLs) as signals to regulate multiple processes in its free-living state in the rhizosphere ..
  94. Wehmeier S, Arnold M, Marlow V, Aouida M, Myka K, Fletcher V, et al. Internalization of a thiazole-modified peptide in Sinorhizobium meliloti occurs by BacA-dependent and -independent mechanisms. Microbiology. 2010;156:2702-13 pubmed publisher
    BacA proteins play key roles in the chronic intracellular infections of Sinorhizobium meliloti, Brucella abortus and Mycobacterium tuberculosis within their respective hosts. S. meliloti, B. abortus and M...
  95. Valverde C, Livny J, Schlüter J, Reinkensmeier J, Becker A, Parisi G. Prediction of Sinorhizobium meliloti sRNA genes and experimental detection in strain 2011. BMC Genomics. 2008;9:416 pubmed publisher
    ..In addition, we have developed a computational method that proved useful to predict sRNA-encoding genes in S. meliloti. We anticipate that this predictive approach can be flexibly implemented in many other bacterial species. ..
  96. Yurgel S, Kahn M. A mutant GlnD nitrogen sensor protein leads to a nitrogen-fixing but ineffective Sinorhizobium meliloti symbiosis with alfalfa. Proc Natl Acad Sci U S A. 2008;105:18958-63 pubmed publisher
    ..In the symbiosis between Sinorhizobium meliloti and alfalfa, mutations in GlnD, the major bacterial nitrogen stress response sensor protein, led to a ..
  97. Wang C, Kemp J, da Fonseca I, Equi R, Sheng X, Charles T, et al. Sinorhizobium meliloti 1021 loss-of-function deletion mutation in chvI and its phenotypic characteristics. Mol Plant Microbe Interact. 2010;23:153-60 pubmed publisher
    ..In Sinorhizobium meliloti, the TCS ExoS/ChvI controls exopolysaccharide succinoglycan production and flagellum biosynthesis...