moraxella

Summary

Summary: A genus of gram-negative, aerobic bacteria occurring as rods (subgenus Moraxella) or cocci (subgenus Branhamella). Its organisms are parasitic on the mucous membranes of humans and other warm-blooded animals.

Top Publications

  1. Sifri C, Brassinga A, Flohr T, Kinchen J, Hazen K, Sawyer R, et al. Moraxella osloensis bacteremia in a kidney transplant recipient. Transpl Int. 2008;21:1011-3 pubmed publisher
  2. Brittain C, Penwarden A, Mearza A, Verity D. Moraxella as a cause of necrotizing fasciitis of the eyelid. Eye (Lond). 2006;20:1312-4 pubmed
  3. Zemlickova H, Urbaskova P, Adamkova V, Motlova J, Lebedova V, Prochazka B. Characteristics of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus isolated from the nasopharynx of healthy children attending day-care centres in the Czech Republic. Epidemiol Infect. 2006;134:1179-87 pubmed
    ..The overall carriage of pathogens was 62.8% (Streptococcus pneumoniae, 38.1%; Haemophilus influenzae, 24.9%; Moraxella catarrhalis, 22.1%; Staphylococcus aureus, 16%)...
  4. Kawasaki H, Tsuda K, Matsushita I, Tonomura K. Lack of homology between two haloacetate dehalogenase genes encoded on a plasmid from Moraxella sp. strain B. J Gen Microbiol. 1992;138:1317-23 pubmed
    Two genes encoding haloacetate dehalogenases, H-1 and H-2, are closely linked on a plasmid from Moraxella sp. strain B. H-1 predominantly acts on fluoroacetate, but H-2 does not...
  5. Shabalin I, Filippova E, Polyakov K, Sadykhov E, Safonova T, Tikhonova T, et al. Structures of the apo and holo forms of formate dehydrogenase from the bacterium Moraxella sp. C-1: towards understanding the mechanism of the closure of the interdomain cleft. Acta Crystallogr D Biol Crystallogr. 2009;65:1315-25 pubmed publisher
    ..The crystal structures of the apo and holo forms of FDH from the methylotrophic bacterium Moraxella sp. C-1 (MorFDH) are reported at 1.96 and 1.95 A resolution, respectively...
  6. Masullo M, Arcari P, de Paola B, Parmeggiani A, Bocchini V. Psychrophilic elongation factor Tu from the antarctic Moraxella sp. Tac II 25: biochemical characterization and cloning of the encoding gene. Biochemistry. 2000;39:15531-9 pubmed
    The elongation factor Tu was isolated from a psychrophilic eubacterial Antarctic Moraxella strain (MoEF-Tu) and its molecular and functional properties were determined...
  7. Dien Bard J, Lewinski M, Summanen P, Deville J. Sepsis with prolonged hypotension due to Moraxella osloensis in a non-immunocompromised child. J Med Microbiol. 2011;60:138-41 pubmed publisher
    We report a case of septicaemia with prolonged, refractory hypotension related to Moraxella osloensis isolated in a non-immunocompromised paediatric patient.
  8. Catry B, Boyen F, Baele M, Dewulf J, de Kruif A, Vaneechoutte M, et al. Recovery of Moraxella ovis from the bovine respiratory tract and differentiation of Moraxella species by tDNA-intergenic spacer PCR. Vet Microbiol. 2007;120:375-80 pubmed
    The purpose of the present study was to identify Moraxella (M...
  9. Chen D, Wang Z, Zhang Y, Sun Z, Zhu Q. An amine: hydroxyacetone aminotransferase from Moraxella lacunata WZ34 for alaninol synthesis. Bioprocess Biosyst Eng. 2008;31:283-9 pubmed
    An amine:hydroxyacetone aminotransferase from an isolated soil bacterium, Moraxella lacunata WZ34, was employed to synthesize alaninol in the presence of hydroxyacetone and isopropylamine in this study...

More Information

Publications97

  1. Shimazu M, Mulchandani A, Chen W. Simultaneous degradation of organophosphorus pesticides and p-nitrophenol by a genetically engineered Moraxella sp. with surface-expressed organophosphorus hydrolase. Biotechnol Bioeng. 2001;76:318-24 pubmed
    b>Moraxella sp., a native soil organism that grows on p-nitrophenol (PNP), was genetically engineered for the simultaneous degradation of organophosphorus (OP) pesticides and p-nitrophenol (PNP)...
  2. Devi P, Naik C, Rodrigues C. Biotransformation of citrinin to decarboxycitrinin using an organic solvent-tolerant marine bacterium, Moraxella sp. MB1. Mar Biotechnol (NY). 2006;8:129-38 pubmed
    ..In the present study, we used an organic solvent-tolerant marine bacterium, Moraxella sp. MB1...
  3. Berrocal A, Scott I, Miller D, Flynn H. Endophthalmitis caused by Moraxella species. Am J Ophthalmol. 2001;132:788-90 pubmed
    ..incidence, clinical presentation, antibiotic sensitivities, and treatment outcomes for endophthalmitis caused by Moraxella species. Consecutive interventional case series...
  4. Tripodi M, Adinolfi L, Rosario P, Ragone E, Utili R. First definite case of aortic valve endocarditis due to Moraxella phenylpyruvica. Eur J Clin Microbiol Infect Dis. 2002;21:480-2 pubmed
    Described here is the first definite case of endocarditis due to Moraxella phenylpyruvica, which occurred in a 50-year-old male with a bicuspid aortic valve...
  5. Davis J, Whipp M, Ashhurst Smith C, DeBoer J, Peel M. Mucoid nitrate-negative Moraxella nonliquefaciens from three patients with chronic lung disease. J Clin Microbiol. 2004;42:3888-90 pubmed
    Mucoid strains of Moraxella nonliquefaciens were recovered from the sputa of three indigenous Australians with chronic lung disease. These atypical strains failed to reduce nitrate, and one strain produced beta-lactamase...
  6. Vuori Holopainen E, Salo E, Saxen H, Vaara M, Tarkka E, Peltola H. Clinical "pneumococcal pneumonia" due to Moraxella osloensis: case report and a review. Scand J Infect Dis. 2001;33:625-7 pubmed
    A previously healthy 6-y-old girl presented with a disease very similar to pneumococcal pneumonia. However, Moraxella osloensis was isolated by lung tap. The patient responded well to a course of parenteral penicillin...
  7. Tan L, Grewal P. Pathogenicity of Moraxella osloensis, a bacterium associated with the nematode Phasmarhabditis hermaphrodita, to the slug Deroceras reticulatum. Appl Environ Microbiol. 2001;67:5010-6 pubmed
    b>Moraxella osloensis, a gram-negative bacterium, is associated with Phasmarhabditis hermaphrodita, a nematode parasite of slugs...
  8. Cerny H, Rogers D, Gray J, Smith D, Hinkley S. Effects of Moraxella (Branhamella) ovis culture filtrates on bovine erythrocytes, peripheral mononuclear cells, and corneal epithelial cells. J Clin Microbiol. 2006;44:772-6 pubmed
    ..Piliated hemolytic Moraxella bovis is recognized as the etiologic agent of IBK...
  9. Angelos J, Spinks P, Ball L, George L. Moraxella bovoculi sp. nov., isolated from calves with infectious bovine keratoconjunctivitis. Int J Syst Evol Microbiol. 2007;57:789-95 pubmed
    ..9 % sequence similarity. On the basis of 16S rRNA gene sequence, the isolates were most closely associated with Moraxella bovis and Moraxella ovis in clade I of the classical moraxellae...
  10. Funk L, O Connor A, Maroney M, Engelken T, Cooper V, Kinyon J, et al. A randomized and blinded field trial to assess the efficacy of an autogenous vaccine to prevent naturally occurring infectious bovine keratoconjunctivis (IBK) in beef calves. Vaccine. 2009;27:4585-90 pubmed publisher
    ..The vaccine at Iowa contained Moraxella bovoculi (M. bovoculi) while the organism used in the Wisconsin herds vaccine was Branhemella ovis (B...
  11. Tryland M, das Neves C, Sunde M, Mørk T. Cervid herpesvirus 2, the primary agent in an outbreak of infectious keratoconjunctivitis in semidomesticated reindeer. J Clin Microbiol. 2009;47:3707-13 pubmed publisher
    ..b>Moraxella sp. isolates were obtained from seven animals, and those from two animals were identified as Moraxella bovoculi...
  12. Angelos J. Moraxella bovoculi and infectious bovine keratoconjunctivitis: cause or coincidence?. Vet Clin North Am Food Anim Pract. 2010;26:73-8, table of contents pubmed publisher
    b>Moraxella bovoculi is a recently described gram-negative coccus that was isolated from eyes of calves with infectious bovine keratoconjunctivitis (IBK, or "pinkeye") in 2002...
  13. Han X, Tarrand J. Moraxella osloensis blood and catheter infections during anticancer chemotherapy: clinical and microbiologic studies of 10 cases. Am J Clin Pathol. 2004;121:581-7 pubmed
    b>Moraxella osloensis, a gram-negative bacterium that is saprophytic on skin and mucosa, rarely causes infections. Moreover, infections in patients with cancer have not been reported. We describe 10 cases of M...
  14. Tan L, Grewal P. Endotoxin activity of Moraxella osloensis against the grey garden slug, Deroceras reticulatum. Appl Environ Microbiol. 2002;68:3943-7 pubmed
    b>Moraxella osloensis is a gram-negative bacterium associated with Phasmarhabditis hermaphrodita, a slug-parasitic nematode that has prospects for biological control of mollusk pests, especially the grey garden slug, Deroceras reticulatum...
  15. Vaneechoutte M, Claeys G, Steyaert S, de Baere T, Peleman R, Verschraegen G. Isolation of Moraxella canis from an ulcerated metastatic lymph node. J Clin Microbiol. 2000;38:3870-1 pubmed
    b>Moraxella canis was isolated in large numbers from an ulcerated supraclavicular lymph node of a terminal patient, who died a few days later...
  16. Berrocal A, Scott I, Miller D, Flynn H. Endophthalmitis caused by Moraxella osloensis. Graefes Arch Clin Exp Ophthalmol. 2002;240:329-30 pubmed
    ..To report the clinical presentation, antibiotic sensitivities, and treatment outcomes of endophthalmitis caused by Moraxella osloensis...
  17. Langin D, Laurell H, Holst L, Belfrage P, Holm C. Gene organization and primary structure of human hormone-sensitive lipase: possible significance of a sequence homology with a lipase of Moraxella TA144, an antarctic bacterium. Proc Natl Acad Sci U S A. 1993;90:4897-901 pubmed
    ..reported unexpected homology between the region surrounding its catalytic site and that of the lipase 2 of Moraxella TA144, an antarctic psychrotrophic bacterium...
  18. Egwu G, Faull W, Bradbury J, Clarkson M. Ovine infectious keratoconjunctivitis: a microbiological study of clinically unaffected and affected sheep's eyes with special reference to Mycoplasma conjunctivae. Vet Rec. 1989;125:253-6 pubmed
    ..The genera Mycoplasma and Acholeplasma were isolated from both groups, and Mycoplasma conjunctivae occurred in 92 affected eyes (38.3 per cent), and 27 unaffected eyes (11.3 per cent)...
  19. Graham D, Band J, Thornsberry C, Hollis D, Weaver R. Infections caused by Moraxella, Moraxella urethralis, Moraxella-like groups M-5 and M-6, and Kingella kingae in the United States, 1953-1980. Rev Infect Dis. 1990;12:423-31 pubmed
    ..1953 to 1980 the Centers for Disease Control received 933 isolates of bacteria belonging to species of the genus Moraxella, Moraxella-like Moraxella urethralis, now renamed Oligella urethralis, unnamed groups M-5 and M-6, and Kingella ..
  20. Angelos J, Ball L, Hess J. Identification and characterization of complete RTX operons in Moraxella bovoculi and Moraxella ovis. Vet Microbiol. 2007;125:73-9 pubmed
    To determine if Moraxella bovoculi (M. bovoculi), a recently characterized coccoid Moraxella that was isolated from the eyes of calves affected with infectious bovine keratoconjunctivitis (IBK), and Moraxella ovis (M...
  21. Embers M, Doyle L, Whitehouse C, Selby E, Chappell M, Philipp M. Characterization of a Moraxella species that causes epistaxis in macaques. Vet Microbiol. 2011;147:367-75 pubmed publisher
    Bacteria of the genus Moraxella have been isolated from a variety of mammalian hosts...
  22. Liu J, Kurihara T, Ichiyama S, Miyagi M, Tsunasawa S, Kawasaki H, et al. Reaction mechanism of fluoroacetate dehalogenase from Moraxella sp. B. J Biol Chem. 1998;273:30897-902 pubmed
    ..The amino acid sequence of fluoroacetate dehalogenase from Moraxella sp. B is similar to that of haloalkane dehalogenase (EC 3.8.1...
  23. Dubay S, Williams E, Mills K, Boerger Fields A. Association of Moraxella ovis with keratoconjunctivitis in mule deer and moose in Wyoming. J Wildl Dis. 2000;36:241-7 pubmed
    ..Moose had severe mucopurulent conjunctivitis, keratitis, and corneal ulceration. Hemolytic, non-piliated Moraxella ovis was isolated from two mule deer and two moose...
  24. Tan A, Blakeway L, Bakaletz L, Boitano M, Clark T, Korlach J, et al. Complete Genome Sequence of Moraxella catarrhalis Strain CCRI-195ME, Isolated from the Middle Ear. Genome Announc. 2017;5: pubmed publisher
    i>Moraxella catarrhalis is an important bacterial pathogen that causes otitis media and exacerbations of chronic obstructive pulmonary disease. Here, we report the complete genome sequence of M...
  25. Suzuki Y, Nishinari C, Endo H, Hiramatsu N, Akiyama K, Koyama T. [Yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--II. Gram-negative bacteria]. Jpn J Antibiot. 2003;56:309-35 pubmed
    ..bacteria were isolated from the clinical materials annually collected from January to December, and consisted of Moraxella subgenus Branhamella catarrhalis, Escherichia coli, Citrobacter freundii, Citrobacter koseri, Klebsiella ..
  26. Kutlesa M, Lepur D, Klinar I, Rudez I, Vincelj J, Bukovski S, et al. Moraxella lacunata: a rare cause of infective endocarditis. Scand J Infect Dis. 2007;39:917-9 pubmed
    We describe the first case of Moraxella lacunata definite native valve endocarditis in a patient with previously normal mitral valves. The disease was complicated with embolizations of the brain and spleen...
  27. Roh K, Kim C, Koh E, Kim M, Yong D, Park S, et al. Three cases of Moraxella osloensis meningitis: a difficult experience in species identification and determination of clinical significance. J Korean Med Sci. 2010;25:501-4 pubmed publisher
    We had three cases of Moraxella osloensis meningitis. The species identification was impossible by conventional and commercial phenotypic tests. However, we could identify the species using the 16S rRNA gene sequencing...
  28. Bosch A, van Houten M, Bruin J, Wijmenga Monsuur A, Trzciński K, Bogaert D, et al. Nasopharyngeal carriage of Streptococcus pneumoniae and other bacteria in the 7th year after implementation of the pneumococcal conjugate vaccine in the Netherlands. Vaccine. 2016;34:531-539 pubmed publisher
    ..Nasopharyngeal carriage of S. pneumoniae, H. influenzae, S. aureus, and Moraxella catarrhalis was determined by conventional culture in 330 PCV10-vaccinated 11-month-old children, 330 PCV7-..
  29. Pavlović D, Mutak S. Synthesis and antibacterial evaluation of novel 4″-glycyl linked quinolyl-azithromycins with potent activity against macrolide-resistant pathogens. Bioorg Med Chem. 2016;24:1255-67 pubmed publisher
    ..In addition, potential lead compounds 9e and 22f demonstrated outstanding levels of activity against Moraxella catarrhalis and inducibly MLSB resistant Staphylococcus aureus...
  30. Ren D, Almudevar A, Murphy T, Lafontaine E, Campagnari A, Luke Marshall N, et al. Serum antibody response to Moraxella catarrhalis proteins in stringently defined otitis prone children. Vaccine. 2017;: pubmed publisher
    b>Moraxella catarrhalis (Mcat) is a frequent pathogen of acute otitis media (AOM) in young children...
  31. Xie C, Yokota A. Transfer of the misnamed [Alysiella] sp. IAM 14971 (=ATCC 29468) to the genus Moraxella as Moraxella oblonga sp. nov. Int J Syst Evol Microbiol. 2005;55:331-4 pubmed
    ..IAM 14971 (=ATCC 29468) is closely related to the genus Moraxella of the gamma-Proteobacteria (96-97 % similarity)...
  32. Alanin M, Nielsen K, von Buchwald C, Skov M, Aanaes K, Høiby N, et al. A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia. Clin Microbiol Infect. 2015;21:1093.e1-7 pubmed publisher
    ..Other common pathogens were P. aeruginosa, Streptococcus pneumoniae, Moraxella catarrhalis and Staphylococcus aureus. The number of patients colonized with P...
  33. Bosch A, Levin E, van Houten M, Hasrat R, Kalkman G, Biesbroek G, et al. Development of Upper Respiratory Tract Microbiota in Infancy is Affected by Mode of Delivery. EBioMedicine. 2016;9:336-345 pubmed publisher
    ..followed by differentiation towards Corynebacterium pseudodiphteriticum/propinquum, Dolosigranulum pigrum, Moraxella catarrhalis/nonliquefaciens, Streptococcus pneumoniae, and/or Haemophilus influenzae dominated communities...
  34. Tsuji M, Ishii Y, Ohno A, Miyazaki S, Yamaguchi K. In vitro and in vivo antibacterial activities of S-4661, a new carbapenem. Antimicrob Agents Chemother. 1998;42:94-9 pubmed
    ..S-4661 was highly active against members of the family Enterobacteriaceae, Haemophilus influenzae, and Moraxella catarrhalis, with MIC90s ranging from 0.032 to 0.5 microg/ml...
  35. Pratap S, Kesari P, Yadav R, Dev A, Narwal M, Kumar P. Acyl chain preference and inhibitor identification of Moraxella catarrhalis LpxA: Insight through crystal structure and computational studies. Int J Biol Macromol. 2017;96:759-765 pubmed publisher
    ..Herein, we present the crystal structure of Moraxella catarrhalis LpxA (McLpxA)...
  36. Tian J, Han X, Lv W, Li Y, Wang H, Fan B, et al. Design, synthesis and structure-bactericidal activity relationships of novel 9-oxime ketolides and reductive epimers of acylides. Bioorg Med Chem Lett. 2017;27:1513-1524 pubmed publisher
    ..pneumoniae, Staphylococcus aureus and Moraxella catarrhalis, while the 2-fluoro analogs 13c (Ar=3-aminopyridyl) and 24b (Ar=3-carbamoylpyridyl) are only ..
  37. Bosch A, de Steenhuijsen Piters W, van Houten M, Chu M, Biesbroek G, Kool J, et al. Maturation of the Infant Respiratory Microbiota, Environmental Drivers and Health Consequences: A Prospective Cohort Study. Am J Respir Crit Care Med. 2017;: pubmed publisher
    ..enrichment of Moraxella already very early in life, followed by later enrichment of Neisseria and Prevotella spp...
  38. Depner M, Ege M, Cox M, Dwyer S, Walker A, Birzele L, et al. Bacterial microbiota of the upper respiratory tract and childhood asthma. J Allergy Clin Immunol. 2017;139:826-834.e13 pubmed publisher
    ..Furthermore, asthma presence was positively associated with a specific operational taxonomic unit from the genus Moraxella in children not exposed to farming, whereas in farm children Moraxella colonization was unrelated to asthma...
  39. Basaran S, Karabiçak N, Simsek Yavuz S, Wiederhold N, Şafak S, Sarıbuğa A, et al. [A case of coccidioidomycosis in Turkey imported from the United States of America]. Mikrobiyol Bul. 2017;51:183-190 pubmed
    ..Pleural fluid culture revealed Moraxella catarrhalis after 24 hours incubation and a mold after 72 hours of incubation...
  40. Yanagihara K, Watanabe A, Aoki N, Matsumoto T, Yoshida M, Sato J, et al. Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012: Gene. J Infect Chemother. 2017;23:587-597 pubmed publisher
    ..Staphylococcus aureus, 225 Streptococcus pneumoniae, 16 Streptococcus pyogenes, 231 Haemophilus influenzae, 147 Moraxella catarrhalis, 167 Klebsiella pneumoniae and 218 Pseudomonas aeruginosa). Ratio of methicillin-resistant S...
  41. Nakai H, Sato T, Uno T, Furukawa E, Kawamura M, Takahashi H, et al. Mutant selection window of four quinolone antibiotics against clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. J Infect Chemother. 2018;24:83-87 pubmed publisher
    ..media are caused by several bacterial species, including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. For the treatment of these diseases, various quinolones are frequently used...
  42. Van Hoecke H, De Paepe A, Lambert E, Van Belleghem J, Cools P, Van Simaey L, et al. Haemophilus influenzae biofilm formation in chronic otitis media with effusion. Eur Arch Otorhinolaryngol. 2016;273:3553-3560 pubmed
    ..7 % were culture positive for bacteria and 47.0 % were culture positive for Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus and/or Streptococcus pneumoniae...
  43. Banoub J, El Aneed A, Cohen A, Joly N. Structural investigation of bacterial lipopolysaccharides by mass spectrometry and tandem mass spectrometry. Mass Spectrom Rev. 2010;29:606-50 pubmed publisher
  44. Min K, Yoon H, Jo I, Ha N, Jin K, Kim J, et al. Structural insights into the apo-structure of Cpf1 protein from Francisella novicida. Biochem Biophys Res Commun. 2018;498:775-781 pubmed publisher
    ..In contrast, the apo Cpf1 from Moraxella bovoculi 237 (MbCpf1) was analyzed as an open form, implying that a large conformational change from an open to ..
  45. Das S, Constantinou M, Daniell M, Taylor H. Moraxella keratitis: predisposing factors and clinical review of 95 cases. Br J Ophthalmol. 2006;90:1236-8 pubmed
    To analyse the clinical presentation, identify predisposing risk factors and evaluate the outcome of treatment of Moraxella keratitis...
  46. Rentier Delrue F, Mande S, Moyens S, Terpstra P, Mainfroid V, Goraj K, et al. Cloning and overexpression of the triosephosphate isomerase genes from psychrophilic and thermophilic bacteria. Structural comparison of the predicted protein sequences. J Mol Biol. 1993;229:85-93 pubmed
    ..The TIM gene from psychrophilic bacteria Moraxella sp. TA137 was cloned and its nucleotide sequence determined...
  47. Enright M, Carter P, Maclean I, McKenzie H. Phylogenetic relationships between some members of the genera Neisseria, Acinetobacter, Moraxella, and Kingella based on partial 16S ribosomal DNA sequence analysis. Int J Syst Bacteriol. 1994;44:387-91 pubmed
    ..of Proteobacteria, including the type strains of Kingella kingae, Neisseria lactamica, Neisseria meningitidis, Moraxella lacunata subsp...
  48. Zhou Y, Lin P, Li Q, Han L, Zheng H, Wei Y, et al. Analysis of the microbiota of sputum samples from patients with lower respiratory tract infections. Acta Biochim Biophys Sin (Shanghai). 2010;42:754-61 pubmed publisher
    ..In addition, some sequences belonging to potential causative agents, such as Mycoplasma, Haemophilus, and Moraxella, were also found, but these sequences were not found by clinical laboratory tests...
  49. Tønjum T, Bukholm G, Bøvre K. Differentiation of some species of Neisseriaceae and other bacterial groups by DNA-DNA hybridization. APMIS. 1989;97:395-405 pubmed
    ..This was studied with type and reference strains of 20 species in Moraxella, Kingella, and other selected Gram-negative groups. Both radioactive and biotin labelling were employed...
  50. Dickey A, Loy J, Bono J, Smith T, Apley M, Lubbers B, et al. Large genomic differences between Moraxella bovoculi isolates acquired from the eyes of cattle with infectious bovine keratoconjunctivitis versus the deep nasopharynx of asymptomatic cattle. Vet Res. 2016;47:31 pubmed publisher
    b>Moraxella bovoculi is a recently described bacterium that is associated with infectious bovine keratoconjunctivitis (IBK) or "pinkeye" in cattle. In this study, closed circularized genomes were generated for seven M...
  51. Wong C, Klieve A, Hamdorf B, Schafer D, Bräu L, Seet S, et al. Family of shuttle vectors for ruminal Bacteroides. J Mol Microbiol Biotechnol. 2003;5:123-32 pubmed
    ..The suitability of pBAC for expression of heterologous genes was demonstrated by expression of the Moraxella species fluoroacetate dehalogenase gene H1 to give intracellular activity of 7 nmol fluoride released/min/mg ..
  52. Henriksen A, Maeland J, Wetzler L. An epitope shared by enterobacterial and neisserial porin proteins. APMIS. 1998;106:818-24 pubmed
    ..Since Po I is broadly distributed among commensal and pathogenic bacteria and has demonstrated immunogenicity in humans, this epitope may play a role in elicitation of "normal" antibodies with immunoprotective activity. ..
  53. Kowalski A, Maboni G, Gressler L, Espíndola J, Balzan C, Tasca C, et al. Antigenic characterization of Moraxella bovis, Moraxella bovoculi and Moraxella ovis strains with potential use in vaccines. Vet Microbiol. 2017;210:56-63 pubmed publisher
    b>Moraxella bovis is historically known as the primary agent of infectious bovine keratoconjunctivitis (IBK)...
  54. Liang Z, Tsigos I, Bouriotis V, Klinman J. Impact of protein flexibility on hydride-transfer parameters in thermophilic and psychrophilic alcohol dehydrogenases. J Am Chem Soc. 2004;126:9500-1 pubmed
    ..These observations provide support for the view that protein dynamics is tightly coupled to the hydrogen-transfer processes in these enzymes. ..
  55. Olzowy B, Kresken M, Havel M, Hafner D, Körber Irrgang B. Antimicrobial susceptibility of bacterial isolates from patients presenting with ear, nose and throat (ENT) infections in the German community healthcare setting. Eur J Clin Microbiol Infect Dis. 2017;36:1685-1690 pubmed publisher
    ..In contrast, cefuroxime axetil seems less likely to be suitable for the treatment of AOM or ARS, as all Moraxella catarrhalis and >99% of the H. influenzae isolates were categorised as intermediate or resistant...
  56. Hasegawa K, Mansbach J, Ajami N, Petrosino J, Freishtat R, Teach S, et al. The relationship between nasopharyngeal CCL5 and microbiota on disease severity among infants with bronchiolitis. Allergy. 2017;72:1796-1800 pubmed publisher
    ..18-8.68; P=.02) and hospital length-of-stay ?3 days (OR, 4.14; 95%CI, 2.08-8.24; P<.001) compared to the Moraxella-dominant profile...
  57. Tobiason D, Buchner J, Thiel W, Gernert K, Karls A. Conserved amino acid motifs from the novel Piv/MooV family of transposases and site-specific recombinases are required for catalysis of DNA inversion by Piv. Mol Microbiol. 2001;39:641-51 pubmed
    Piv, a site-specific invertase from Moraxella lacunata, exhibits amino acid homology with the transposases of the IS110/IS492 family of insertion elements...
  58. Sosa V, Zunino P. Diversity of Moraxella spp. strains recovered from infectious bovine keratoconjunctivitis cases in Uruguay. J Infect Dev Ctries. 2013;7:819-24 pubmed publisher
    ..IBK is caused by members of the genus Moraxella and therapeutic and preventive measures have shown limited success...
  59. Nonaka S, Matsuzaki K, Kazama T, Nishiyama H, Ida Y, Koyano S, et al. Antimicrobial susceptibility and mechanisms of high-level macrolide resistance in clinical isolates of Moraxella nonliquefaciens. J Med Microbiol. 2014;63:242-7 pubmed publisher
    ..and the molecular mechanism involved in conferring high-level macrolide resistance in 47 clinical isolates of Moraxella nonliquefaciens from Japan. Antimicrobial susceptibility was determined using Etest and agar dilution methods...
  60. Freeman J, Altieri R, Freeman A, Kuo T, Sardinha F, Buckingham C, et al. Inappropriate breast secretions of possible bacterial etiology in the parous nonpuerperal female. J Natl Med Assoc. 1994;86:203-8 pubmed
    ..b>Moraxella osloensis was identified and found sensitive to ampicillin and tetracycline but resistant to trimethoprim...
  61. Akerstedt J, Hofshagen M. Bacteriological investigation of infectious keratoconjunctivitis in Norwegian sheep. Acta Vet Scand. 2004;45:19-26 pubmed
    ..b>Moraxella (Branhamella) ovis was isolated from 28% of sampled animals in affected herds and from 10% of sampled animals in ..
  62. Kaur R, Morris M, Pichichero M. Epidemiology of Acute Otitis Media in the Postpneumococcal Conjugate Vaccine Era. Pediatrics. 2017;140: pubmed publisher
    ..The proportion of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis causing AOM had dynamic changes during the past decade...
  63. Zeineldin M, Lowe J, de Godoy M, Maradiaga N, Ramirez C, Ghanem M, et al. Disparity in the nasopharyngeal microbiota between healthy cattle on feed, at entry processing and with respiratory disease. Vet Microbiol. 2017;208:30-37 pubmed publisher
    ..While the predominant genera were Moraxella, Mycoplasma and Acinetobacter...
  64. Yamashita Y, Nakamura N, Omiya K, Nishikawa J, Kawahara H, Obata H. Identification of an antifreeze lipoprotein from Moraxella sp. of Antarctic origin. Biosci Biotechnol Biochem. 2002;66:239-47 pubmed
    ..Among these AFP-producing bacteria, strain No. 82 had the highest antifreeze activity and was identified as Moraxella sp. The optimum temperature and pH for the production of AFP were 5 degrees C and 7.0, respectively...
  65. Nandakumar K, Keeler W, Schraft H, Leung K. Visible laser and UV-A radiation impact on a PNP degrading Moraxella strain and its rpoS mutant. Biotechnol Bioeng. 2006;94:793-802 pubmed
    The role of stationary phase sigma factor gene (rpoS) in the stress response of Moraxella strain when exposed to radiation was determined by comparing the stress responses of the wild-type (WT) and its rpoS knockout (KO) mutant...
  66. Torumkuney D, Chaiwarith R, Reechaipichitkul W, Malatham K, Chareonphaibul V, Rodrigues C, et al. Results from the Survey of Antibiotic Resistance (SOAR) 2012-14 in Thailand, India, South Korea and Singapore. J Antimicrob Chemother. 2016;71 Suppl 1:i3-19 pubmed publisher
    ..respiratory tract isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis collected in 2012-14 from four Asian countries...
  67. Shen H, Gould S, Kinyon J, Opriessnig T, O Connor A. Development and evaluation of a multiplex real-time PCR assay for the detection and differentiation of Moraxella bovis, Moraxella bovoculi and Moraxella ovis in pure culture isolates and lacrimal swabs collected from conventionally raised cattle. J Appl Microbiol. 2011;111:1037-43 pubmed publisher
    To develop a multiplex real-time PCR assay for the detection and differentiation of Moraxella bovis (M. bovis), M. bovoculi and M. ovis...
  68. Brányik T, Kuncova G, Paca J. The use of silica gel prepared by sol-gel method and polyurethane foam as microbial carriers in the continuous degradation of phenol. Appl Microbiol Biotechnol. 2000;54:168-72 pubmed
    ..Coating the ceramic foam with a layer of cells immobilized in colloidal SiO2 enhanced the phenol degradation efficiency during the first 3 days of the PBRC operation, in comparison with untreated ceramic packing. ..
  69. Salter S, Turner C, Watthanaworawit W, de Goffau M, Wagner J, Parkhill J, et al. A longitudinal study of the infant nasopharyngeal microbiota: The effects of age, illness and antibiotic use in a cohort of South East Asian children. PLoS Negl Trop Dis. 2017;11:e0005975 pubmed publisher
    ..In this cohort it is dominated by five taxa: Moraxella, Streptococcus, Haemophilus, Corynebacterium and an uncharacterized Flavobacteriaceae taxon of 93% nucleotide ..
  70. Martinez F, Guerra S. Early Origins of Asthma: Role of Microbial Dysbiosis and Metabolic Dysfunction. Am J Respir Crit Care Med. 2017;: pubmed publisher
    ..Early colonization of the airway by pathogenic bacteria such as Streptococci and Moraxella may predispose for recurrent wheezing LRIs and subsequent asthma...
  71. Angelos J, Ball L. Differentiation of Moraxella bovoculi sp. nov. from other coccoid moraxellae by the use of polymerase chain reaction and restriction endonuclease analysis of amplified DNA. J Vet Diagn Invest. 2007;19:532-4 pubmed
    b>Moraxella ovis was historically the only coccoid Moraxella identified in cultures of ocular fluid from cattle with infectious bovine keratoconjunctivitis (IBK) and could be morphologically and biochemically differentiated from Moraxella ..
  72. Carrano L, Alifano P, Corti E, Bucci C, Donadio S. A new inhibitor of the transcription-termination factor Rho. Biochem Biophys Res Commun. 2003;302:219-25 pubmed
    ..BI-K0058 does not affect photolabeling of Rho by ATP. The results of gel mobility shift experiments with a natural RNA substrate demonstrate that BI-K0058 inhibits the formation of the ATP-independent high affinity Rho-RNA complex. ..
  73. Gruber M, van der Meer G, Ling B, Barber C, Mills N, Neeff M, et al. The bacterial species associated with aspirated foreign bodies in children. Auris Nasus Larynx. 2018;45:598-602 pubmed publisher
    ..with the most common cultured organisms being: Streptococcus pneumonia (4/12%), Haemophilus influenza (4/12%), Moraxella catarrhalis (4/12%)...
  74. Bruijn J, Verhage J, Bosboom R, Brus F. [Septic arthritis in two young children caused by unusual gram-negative pathogens]. Ned Tijdschr Geneeskd. 2000;144:1494-7 pubmed
    ..In the boy, a Moraxella was cultured from the synovial fluid using an aerobic blood culture system...
  75. Wren M, Caskey J, Liu D, Embers M. Septic arthritis due to moraxella osloensis in a rhesus macaque (Macaca mulatta). Comp Med. 2013;63:521-7 pubmed
    ..Arthrocentesis and culture of joint fluid revealed Moraxella-like organisms...
  76. Murphy T, Brauer A, Johnson A, Wilding G, Koszelak Rosenblum M, Malkowski M. A Cation-binding Surface Protein as a Vaccine Antigen to Prevent Moraxella catarrhalis Otitis Media and Infections in Chronic Obstructive Pulmonary Disease. Clin Vaccine Immunol. 2017;: pubmed publisher
    i>Moraxella catarrhalis is an exclusively human respiratory tract pathogen that is a common cause of otitis media in children and respiratory tract infections in adults with chronic obstructive pulmonary disease...
  77. Moore L, Rutter J. Antigenic analysis of fimbrial proteins from Moraxella bovis. J Clin Microbiol. 1987;25:2063-70 pubmed
    Fimbrial proteins were extracted from 15 isolates of Moraxella bovis, and antisera to each of the preparations were raised in rabbits...
  78. Ichiyama S, Kurihara T, Miyagi M, Galkin A, Tsunasawa S, Kawasaki H, et al. Catalysis-linked inactivation of fluoroacetate dehalogenase by ammonia: a novel approach to probe the active-site environment. J Biochem. 2002;131:671-7 pubmed
    Fluoroacetate dehalogenase from Moraxella sp. B (FAc-DEX) catalyzes the hydrolytic dehalogenation of fluoroacetate and other haloacetates...
  79. Otsuka T, Kirkham C, Johnson A, Jones M, Murphy T. Substrate binding protein SBP2 of a putative ABC transporter as a novel vaccine antigen of Moraxella catarrhalis. Infect Immun. 2014;82:3503-12 pubmed publisher
    b>Moraxella catarrhalis is a common respiratory tract pathogen that causes otitis media in children and infections in adults with chronic obstructive pulmonary disease...
  80. Ray S, Rajeshwari R, Sharma Y, Sonti R. A high-molecular-weight outer membrane protein of Xanthomonas oryzae pv. oryzae exhibits similarity to non-fimbrial adhesins of animal pathogenic bacteria and is required for optimum virulence. Mol Microbiol. 2002;46:637-47 pubmed
    ..exhibits significant similarity to non-fimbrial adhesins of animal pathogenic bacteria such as Yersinia YadA and Moraxella UspA1...
  81. de Baere T, Muylaert A, Everaert E, Wauters G, Claeys G, Verschraegen G, et al. Bacteremia due to Moraxella atlantae in a cancer patient. J Clin Microbiol. 2002;40:2693-5 pubmed
    ..Sequencing of the 16S rRNA gene revealed its identity as Moraxella atlantae, a species isolated only rarely and published only once as causing infection...
  82. Cullen J, Lithio A, Seetharam A, Zheng Y, Li G, Nettleton D, et al. Microbial community sequencing analysis of the calf eye microbiota and relationship to infectious bovine keratoconjunctivitis. Vet Microbiol. 2017;207:267-279 pubmed publisher
    Infectious bovine keratoconjunctivitis (IBK) is an important production limiting disease in cattle. Moraxella bovis has historically been considered the primary causal agent; however, vaccines have not been consistently shown as ..
  83. Ternavasio de la Vega H, Marcos García A, Pisos Alamo E, Bolaños Rivero M, Hernández Cabrera M, Pérez Arellano J. Compartmental syndrome of the upper limb due to Moraxella lacunata infection: a link to patera foot syndrome?. Int J Infect Dis. 2010;14 Suppl 3:e302-4 pubmed publisher
    We report a case of compartmental syndrome of the left upper limb secondary to a severe Moraxella lacunata infection, an unusual pathogen, occurring in a young black male immigrant to the island of Gran Canaria, Spain...
  84. Leung K, Moore M, Lee H, Trevors J. Effect of carbon starvation on p-nitrophenol degradation by a Moraxella strain in buffer and river water. FEMS Microbiol Ecol. 2005;51:237-45 pubmed
    This study examines the effect of carbon starvation on the ability of a Moraxella sp. strain to degrade p-nitrophenol (PNP)...
  85. Ballal M, Martena S. First case report of Moraxella osloensis diarrhea in a hemolytic uremic syndrome/acute renal failure child from rural coastal India-Manipal, Karnataka. Indian J Pediatr. 2013;80:255-7 pubmed publisher
    The authors report a rare case of diarrhea caused by Moraxella osloensis in a pediatric child with Hemolytic Uremic Syndrome/Acute Renal Failure (HUS/ARF)...
  86. Odutola A, Antonio M, Owolabi O, Bojang A, Foster Nyarko E, Donkor S, et al. Comparison of the prevalence of common bacterial pathogens in the oropharynx and nasopharynx of gambian infants. PLoS ONE. 2013;8:e75558 pubmed publisher
    ..Therefore, trials of pneumococcal protein vaccines need to evaluate their impact on carriage of other potentially pathogenic bacteria in addition to the pneumococcus...
  87. Whitcher J, Cevallos V. Moraxella, down but not out--the eye bug that won't go away. Br J Ophthalmol. 2006;90:1215-6 pubmed
  88. Yu D, Volponi J, Chhabra S, Brinker C, Mulchandani A, Singh A. Aqueous sol-gel encapsulation of genetically engineered Moraxella spp. cells for the detection of organophosphates. Biosens Bioelectron. 2005;20:1433-7 pubmed
    ..b>Moraxella spp...