serratia marcescens

Summary

Summary: A species of gram-negative, facultatively anaerobic, rod-shaped bacteria found in soil, water, food, and clinical specimens. It is a prominent opportunistic pathogen for hospitalized patients.

Top Publications

  1. Buffet Bataillon S, Rabier V, Betremieux P, Beuchee A, Bauer M, Pladys P, et al. Outbreak of Serratia marcescens in a neonatal intensive care unit: contaminated unmedicated liquid soap and risk factors. J Hosp Infect. 2009;72:17-22 pubmed publisher
    This study describes an outbreak of Serratia marcescens and its investigation and control in a neonatal intensive care unit (NICU). During a three-month period, five infants were colonised or infected by a single strain of S. marcescens...
  2. Pekkonen M, Laakso J. Temporal changes in species interactions in simple aquatic bacterial communities. BMC Ecol. 2012;12:18 pubmed publisher
    ..We used Serratia marcescens and Novosphingobium capsulatum bacteria to study how the interaction between resource environment and ..
  3. Voelz A, Muller A, Gillen J, Le C, Dresbach T, Engelhart S, et al. Outbreaks of Serratia marcescens in neonatal and pediatric intensive care units: clinical aspects, risk factors and management. Int J Hyg Environ Health. 2010;213:79-87 pubmed publisher
    The following recommendations are derived from a systematic analysis of 34 Serratia marcescens outbreaks described in 27 publications from neonatal and pediatric intensive care units (NICU, PICU), in which genotyping methods were used to ..
  4. Kalivoda E, Stella N, O Dee D, Nau G, Shanks R. The cyclic AMP-dependent catabolite repression system of Serratia marcescens mediates biofilm formation through regulation of type 1 fimbriae. Appl Environ Microbiol. 2008;74:3461-70 pubmed publisher
    ..This study investigates the roles of glucose and the catabolite repression system in Serratia marcescens biofilm formation...
  5. Friedman N, Kotsanas D, Brett J, Billah B, Korman T. Investigation of an outbreak of Serratia marcescens in a neonatal unit via a case-control study and molecular typing. Am J Infect Control. 2008;36:22-8 pubmed publisher
    In March 2004, infection or colonization with Serratia marcescens affected one third of all neonates in a newborn services unit (NBS).
  6. Looney E, Sutherland K, Lipp E. Effects of temperature, nutrients, organic matter and coral mucus on the survival of the coral pathogen, Serratia marcescens PDL100. Environ Microbiol. 2010;12:2479-85 pubmed publisher
    b>Serratia marcescens is an enteric bacterium that causes white pox disease in elkhorn coral, Acropora palmata; however, it remains unclear if the pathogenic strain has adapted to seawater or if it requires a host or reservoir for survival...
  7. Lee S, Woo S, Park K, Kim J, Song J, Park K, et al. Serratia marcescens endophthalmitis associated with intravitreal injections of bevacizumab. Eye (Lond). 2010;24:226-32 pubmed publisher
    To report two cases of Serratia marcescens endophthalmitis related to presumed aliquot drug contamination, and to determine the incidence of acute endophthalmitis after intravitreal injection of bevacizumab...
  8. Samuelsson A, Isaksson B, Hanberger H, Olhager E. Late-onset neonatal sepsis, risk factors and interventions: an analysis of recurrent outbreaks of Serratia marcescens, 2006-2011. J Hosp Infect. 2014;86:57-63 pubmed publisher
    Between 2006 and 2011, 11 patients with Serratia marcescens sepsis and 47 patients colonized due to the spread of various clones were observed. These recurrent clusters brought about interventions to reduce spread between patients...
  9. Perez C, Fujii Y, Fauls M, Hummel J, Breitschwerdt E. Fatal aortic endocarditis associated with community-acquired Serratia marcescens infection in a dog. J Am Anim Hosp Assoc. 2011;47:133-7 pubmed publisher
    ..Echocardiography in combination with blood cultures resulted in a diagnosis of nonhospital-acquired Serratia marcescens bacteremia and aortic valve endocarditis...

More Information

Publications90

  1. Hu Z, Zhao W. Identification of plasmid- and integron-borne blaIMP-1 and blaIMP-10 in clinical isolates of Serratia marcescens. J Med Microbiol. 2009;58:217-21 pubmed publisher
    ..This study identified plasmid- and integron-borne bla(IMP-1) and bla(IMP-10) in clinical isolates of Serratia marcescens. The bla(IMP-1) and bla(IMP-10) gene cassettes were carried by a class 1 integron and followed by the aac(6'..
  2. Krediet C, Ritchie K, Cohen M, Lipp E, Sutherland K, Teplitski M. Utilization of mucus from the coral Acropora palmata by the pathogen Serratia marcescens and by environmental and coral commensal bacteria. Appl Environ Microbiol. 2009;75:3851-8 pubmed publisher
    ..commensal bacteria ("Photobacterium mandapamensis" and Halomonas meridiana) and by opportunistic Serratia marcescens pathogens. S...
  3. Mahlen S. Serratia infections: from military experiments to current practice. Clin Microbiol Rev. 2011;24:755-91 pubmed publisher
    Serratia species, in particular Serratia marcescens, are significant human pathogens. S. marcescens has a long and interesting taxonomic, medical experimentation, military experimentation, and human clinical infection history...
  4. Bakkiyaraj D, Sivasankar C, Pandian S. Inhibition of quorum sensing regulated biofilm formation in Serratia marcescens causing nosocomial infections. Bioorg Med Chem Lett. 2012;22:3089-94 pubmed publisher
    b>Serratia marcescens is an opportunistic pathogen causing severe urinary tract infections in hospitalized individuals. Infections of S. marcescens are of great concern because of its increasing resistance towards conventional antibiotics...
  5. Ozgen A, Sezen K, Demir I, Demirbag Z, Nalcacioglu R. Molecular characterization of chitinase genes from a local isolate of Serratia marcescens and their contribution to the insecticidal activity of Bacillus thuringiensis strains. Curr Microbiol. 2013;67:499-504 pubmed publisher
    The chitinase B (chiB) and C (chiC) genes and flanking regions from a local isolate of Serratia marcescens were cloned individually and sequenced...
  6. Letoffe S, Redeker V, Wandersman C. Isolation and characterization of an extracellular haem-binding protein from Pseudomonas aeruginosa that shares function and sequence similarities with the Serratia marcescens HasA haemophore. Mol Microbiol. 1998;28:1223-34 pubmed
    ..b>Serratia marcescens also secretes a haem-binding protein, HasA, which functions as a haemophore that catches haem and shuttles ..
  7. Maltezou H, Tryfinopoulou K, Katerelos P, Ftika L, Pappa O, Tseroni M, et al. Consecutive Serratia marcescens multiclone outbreaks in a neonatal intensive care unit. Am J Infect Control. 2012;40:637-42 pubmed publisher
    This report describes 3 consecutive outbreaks caused by genetically unrelated Serratia marcescens clones that occurred in a neonatal intensive care unit (NICU) over a 35-month period...
  8. Lu C, Lai H, Hsieh S, Chen J. Resveratrol ameliorates Serratia marcescens-induced acute pneumonia in rats. J Leukoc Biol. 2008;83:1028-37 pubmed publisher
    b>Serratia marcescens is an important nosocomial pathogen, which has been especially problematic as a cause of hospital-acquired pneumonia in the past two decades. Treatment of S...
  9. Dusane D, Pawar V, Nancharaiah Y, Venugopalan V, Kumar A, Zinjarde S. Anti-biofilm potential of a glycolipid surfactant produced by a tropical marine strain of Serratia marcescens. Biofouling. 2011;27:645-54 pubmed publisher
    A tropical marine bacterium isolated from the hard coral, Symphyllia sp. was identified as Serratia marcescens on the basis of morphological, biochemical and 16S rDNA analysis...
  10. Faro J, Katz A, Berens P, Ross P. Premature termination of nursing secondary to Serratia marcescens breast pump contamination. Obstet Gynecol. 2011;117:485-6 pubmed publisher
    b>Serratia marcescens, a known pathogen associated with postpartum mastitis, may be identified by its characteristic pigmentation. A 36-year-old P0102 woman presented postpartum and said that her breast pump tubing had turned bright pink...
  11. Alper S, McElwee M, Apfeld J, Lackford B, Freedman J, Schwartz D. The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. J Biol Chem. 2010;285:1822-8 pubmed publisher
    ..Finally, we demonstrate that the p38 MAPK pathway in C. elegans is activated to a similar extent by both pathogenic and nonpathogenic bacteria, suggesting that both can induce the nematode innate immune response. ..
  12. Friman V, Lindstedt C, Hiltunen T, Laakso J, Mappes J. Predation on multiple trophic levels shapes the evolution of pathogen virulence. PLoS ONE. 2009;4:e6761 pubmed publisher
    ..Exposing opportunistic bacterial pathogen Serratia marcescens to predation by protozoan Tetrahymena thermophila decreased its virulence when measured as host moth ..
  13. Nastro M, Monge R, Zintgraff J, Vaulet L, Boutureira M, Famiglietti A, et al. First nosocomial outbreak of VIM-16-producing Serratia marcescens in Argentina. Clin Microbiol Infect. 2013;19:617-9 pubmed publisher
    Seven metallo-?-lactamase-positive isolates of Serratia marcescens were recovered from three patients hospitalized in a neonatal ward in an Argentinean hospital during the period July-September 2011...
  14. Fender J, Bender C, Stella N, Lahr R, Kalivoda E, Shanks R. Serratia marcescens quinoprotein glucose dehydrogenase activity mediates medium acidification and inhibition of prodigiosin production by glucose. Appl Environ Microbiol. 2012;78:6225-35 pubmed publisher
    b>Serratia marcescens is a model organism for the study of secondary metabolites...
  15. Stella N, Kalivoda E, O Dee D, Nau G, Shanks R. Catabolite repression control of flagellum production by Serratia marcescens. Res Microbiol. 2008;159:562-8 pubmed publisher
    b>Serratia marcescens is an emerging opportunistic pathogen with a remarkably broad host range. The cAMP-regulated catabolite repression system of S...
  16. Carrër A, Poirel L, Pitout J, Church D, Nordmann P. Occurrence of an SME-2-producing Serratia marcescens isolate in Canada. Int J Antimicrob Agents. 2008;31:181-2 pubmed
  17. Bando H, Okado K, Guelbeogo W, Badolo A, Aonuma H, Nelson B, et al. Intra-specific diversity of Serratia marcescens in Anopheles mosquito midgut defines Plasmodium transmission capacity. Sci Rep. 2013;3:1641 pubmed publisher
    ..b>Serratia marcescens isolated from either laboratory-reared mosquitoes or wild populations in Burkina Faso shows great ..
  18. Gouda H, Sunazuka T, Iguchi K, Sugawara A, Hirose T, Noguchi Y, et al. Computer-aided rational molecular design of argifin-derivatives with increased inhibitory activity against chitinase B from Serratia marcescens. Bioorg Med Chem Lett. 2009;19:2630-3 pubmed publisher
    ..we undertook rational molecular design of argifin-derivatives and tested them against chitinase B from Serratia marcescens (SmChiB)...
  19. Diaz Albiter H, Sant Anna M, Genta F, Dillon R. Reactive oxygen species-mediated immunity against Leishmania mexicana and Serratia marcescens in the sand phlebotomine fly Lutzomyia longipalpis. J Biol Chem. 2012;287:23995-4003 pubmed publisher
    ..we show that the concentration of ROS increased in sand fly midguts after they fed on the insect pathogen Serratia marcescens but not after feeding on the Leishmania that uses the sand fly as a vector...
  20. Langrock M, Linde H, Landthaler M, Karrer S. Leg ulcers and abscesses caused by Serratia marcescens. Eur J Dermatol. 2008;18:705-7 pubmed publisher
    ..In addition, he had a post-thrombotic syndrome of the lower right leg. Serratia marcescens was the only microorganism isolated from all cultures performed...
  21. Ishii K, Adachi T, Imamura K, Takano S, Usui K, Suzuki K, et al. Serratia marcescens induces apoptotic cell death in host immune cells via a lipopolysaccharide- and flagella-dependent mechanism. J Biol Chem. 2012;287:36582-92 pubmed publisher
    Injection of Serratia marcescens into the blood (hemolymph) of the silkworm, Bombyx mori, induced the activation of c-Jun NH(2)-terminal kinase (JNK), followed by caspase activation and apoptosis of blood cells (hemocytes)...
  22. Cronin S, Nehme N, Limmer S, Liegeois S, Pospisilik J, Schramek D, et al. Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection. Science. 2009;325:340-3 pubmed publisher
    ..screen to uncover genes involved in susceptibility or resistance to intestinal infection with the bacterium Serratia marcescens. We first employed whole-organism gene suppression, followed by tissue-specific silencing in gut epithelium ..
  23. Hornsey M, Ellington M, Doumith M, Hudson S, Livermore D, Woodford N. Tigecycline resistance in Serratia marcescens associated with up-regulation of the SdeXY-HasF efflux system also active against ciprofloxacin and cefpirome. J Antimicrob Chemother. 2010;65:479-82 pubmed publisher
    ..by RND-type transporters is known to confer resistance to tigecycline in several Enterobacteriaceae species and we examined the potential of this mechanism in Serratia marcescens using a clinical isolate and laboratory-selected mutants.
  24. George P, Gupta A, Gopal M, Thomas L, Thomas G. Multifarious beneficial traits and plant growth promoting potential of Serratia marcescens KiSII and Enterobacter sp. RNF 267 isolated from the rhizosphere of coconut palms (Cocos nucifera L.). World J Microbiol Biotechnol. 2013;29:109-17 pubmed publisher
    ..bacteria designated as KiSII and RNF 267 isolated from the rhizosphere of coconut palms were identified as Serratia marcescens and Enterobacter sp. based on their phenotypic features, BIOLOG studies and 16S rRNA gene sequence analysis...
  25. Tsakris A, Voulgari E, Poulou A, Kimouli M, Pournaras S, Ranellou K, et al. In vivo acquisition of a plasmid-mediated bla(KPC-2) gene among clonal isolates of Serratia marcescens. J Clin Microbiol. 2010;48:2546-9 pubmed publisher
    Three patients admitted to a Greek hospital were infected with Serratia marcescens isolates that exhibited reduced susceptibility to carbapenems and harbored Klebsiella pneumoniae carbapenemase (KPC) enzymes...
  26. Cai J, Zhou H, Zhang R, Chen G. Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. Antimicrob Agents Chemother. 2008;52:2014-8 pubmed publisher
    Twenty-one Serratia marcescens, ten Klebsiella pneumoniae, and one Escherichia coli isolate with carbapenem resistance or reduced carbapenem susceptibility were recovered from intensive care units (ICUs) in our hospital...
  27. Zees A, Pyrpassopoulos S, Vorgias C. Insights into the role of the (alpha+beta) insertion in the TIM-barrel catalytic domain, regarding the stability and the enzymatic activity of chitinase A from Serratia marcescens. Biochim Biophys Acta. 2009;1794:23-31 pubmed publisher
    Chitinase A (ChiA) from Serratia marcescens is a mesophilic enzyme with high catalytic activity and high stability...
  28. English G, Trunk K, Rao V, Srikannathasan V, Hunter W, Coulthurst S. New secreted toxins and immunity proteins encoded within the Type VI secretion system gene cluster of Serratia marcescens. Mol Microbiol. 2012;86:921-36 pubmed publisher
    ..we identified two secreted substrates of the antibacterial T6SS from the opportunistic human pathogen, Serratia marcescens. Ssp1 and Ssp2, both encoded within the T6SS gene cluster, were confirmed as antibacterial toxins delivered ..
  29. Sun J, Zhang L, Rao B, Shen Y, Wei D. Enhanced acetoin production by Serratia marcescens H32 with expression of a water-forming NADH oxidase. Bioresour Technol. 2012;119:94-8 pubmed publisher
    Cofactor engineering was employed to enhance production of acetoin by Serratia marcescens H32. 2,3-Butanediol was a major byproduct of acetoin fermentation by S. marcescens H32...
  30. Zeng H, Cai Y, Liao X, Zhang F, Zhang D. Production, characterization, cloning and sequence analysis of a monofunctional catalase from Serratia marcescens SYBC08. J Basic Microbiol. 2011;51:205-14 pubmed publisher
    A monofunctional catalase from Serratia marcescens SYBC08 produced by liquid state fermentation in 7 liter fermenter was isolated and purified by ammonium sulfate precipitation (ASP), ion exchange chromatography (IEC), and gel filtration ..
  31. Syed Ibrahim K, Bakkiyaraj D, James R, Ganesh Babu T, Karutha Pandian S. Isolation and sequence analysis of a small cryptic plasmid pRK10 from a corrosion inhibitor degrading strain Serratia marcescens ACE2. Plasmid. 2009;62:183-90 pubmed publisher
    The nucleotide sequence of a smallest cryptic plasmid pRK10 of Serratia marcescens ACE2 was determined. When compared to the all other plasmids reported so far from S...
  32. Kumar R, Acharya C, Joshi S. Isolation and analyses of uranium tolerant Serratia marcescens strains and their utilization for aerobic uranium U(VI) bioadsorption. J Microbiol. 2011;49:568-74 pubmed publisher
    ..1 % U(3)O(8)), indicated a wide occurrence of Serratia marcescens. Five representative S. marcescens isolates were characterized by a polyphasic taxonomic approach...
  33. Matsushita K, Uchiyama J, Kato S, Ujihara T, Hoshiba H, Sugihara S, et al. Morphological and genetic analysis of three bacteriophages of Serratia marcescens isolated from environmental water. FEMS Microbiol Lett. 2009;291:201-8 pubmed publisher
    Increases in multidrug-resistant strains of Serratia marcescens are of great concern in pediatrics, especially in neonatal intensive care units...
  34. Alagely A, Krediet C, Ritchie K, Teplitski M. Signaling-mediated cross-talk modulates swarming and biofilm formation in a coral pathogen Serratia marcescens. ISME J. 2011;5:1609-20 pubmed publisher
    ..were isolated from surfaces of asymptomatic corals inhibited biofilm formation by the white pox pathogen Serratia marcescens PDL100, indicating that signals capable of affecting the associated microbiota are produced in situ...
  35. Fuls J, Rodgers N, Fischler G, Howard J, Patel M, Weidner P, et al. Alternative hand contamination technique to compare the activities of antimicrobial and nonantimicrobial soaps under different test conditions. Appl Environ Microbiol. 2008;74:3739-44 pubmed publisher
    ..When the soap volume was normalized based on weight (approximately 3 g), nonantimicrobial soap reduced Serratia marcescens by 1.08 log(10) counts, compared to the 3.83-log(10) reduction caused by the antimicrobial soap (P < 0...
  36. Kim S, Park Y, Yu J, Kim Y, Han K. Prevalence and characteristics of aac(6')-Ib-cr in AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens: a multicenter study from Korea. Diagn Microbiol Infect Dis. 2009;63:314-8 pubmed publisher
    ..A total of 479 clinical isolates of Enterobacter cloacae (179), Citrobacter freundii (134), and Serratia marcescens (166) from 12 laboratories between March and July 2005 were examined...
  37. Zhou W, Jin Z, Wan Y. Apoptosis of human lung adenocarcinoma A549 cells induced by prodigiosin analogue obtained from an entomopathogenic bacterium Serratia marcescens. Appl Microbiol Biotechnol. 2010;88:1269-75 pubmed publisher
    An entomopathogenic bacterial strain SCQ1 was isolated from silkworm (Bombyx mori) and identified as Serratia marcescens via 16S rRNA gene analysis. This strain produces a red pigment that causes acute septicemia of silkworm...
  38. Vaaje Kolstad G, Horn S, Sørlie M, Eijsink V. The chitinolytic machinery of Serratia marcescens--a model system for enzymatic degradation of recalcitrant polysaccharides. FEBS J. 2013;280:3028-49 pubmed publisher
  39. Maseda H, Hashida Y, Konaka R, Shirai A, Kourai H. Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. Antimicrob Agents Chemother. 2009;53:5230-5 pubmed publisher
    b>Serratia marcescens is an important opportunistic pathogen in hospitals, where quaternary ammonium compounds are often used for disinfection...
  40. Samonis G, Vouloumanou E, Christofaki M, Dimopoulou D, Maraki S, Triantafyllou E, et al. Serratia infections in a general hospital: characteristics and outcomes. Eur J Clin Microbiol Infect Dis. 2011;30:653-60 pubmed publisher
    ..5 years) were identified; 37.7% were outpatients. Sixty-five (84.4%) of the 77 included patients had a Serratia marcescens isolate; the remaining 12 patients had a non-marcescens Serratia spp...
  41. Gouda H, Yanai Y, Sugawara A, Sunazuka T, Omura S, Hirono S. Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens. Bioorg Med Chem. 2008;16:3565-79 pubmed publisher
    ..the natural-product cyclopentapeptide chitinase inhibitors argifin and argadin with chitinase B (ChiB) from Serratia marcescens. Argadin inhibited ChiB with an inhibition constant (K(i)) value of 20 nM, which was three orders of ..
  42. Lin C, Horng J, Yang C, Tsai Y, Su L, Wei C, et al. RssAB-FlhDC-ShlBA as a major pathogenesis pathway in Serratia marcescens. Infect Immun. 2010;78:4870-81 pubmed publisher
    b>Serratia marcescens has long been recognized as an important opportunistic pathogen, but the underlying pathogenesis mechanism is not completely clear. Here, we report a key pathogenesis pathway in S...
  43. Friman V, Laakso J. Pulsed-resource dynamics constrain the evolution of predator-prey interactions. Am Nat. 2011;177:334-45 pubmed publisher
    ..how extrinsic resource pulses affect evolutionary and ecological dynamics between the prey bacterium Serratia marcescens and the predatory protozoan Tetrahymena thermophila...
  44. Gerc A, Song L, Challis G, Stanley Wall N, Coulthurst S. The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin. PLoS ONE. 2012;7:e44673 pubmed publisher
    ..We observed that the enteric insect pathogen, Serratia marcescens Db10, produced a diffusible compound that inhibited the growth of Bacillis subtilis and Staphyloccocus ..
  45. Minato Y, Shahcheraghi F, Ogawa W, Kuroda T, Tsuchiya T. Functional gene cloning and characterization of the SsmE multidrug efflux pump from Serratia marcescens. Biol Pharm Bull. 2008;31:516-9 pubmed
    We cloned a gene responsible for multidrug resistance from chromosomal DNA of Serratia marcescens, and determined the nucleotide sequence. We designated the gene as ssmE...
  46. Velasco C, Rodríguez Martínez J, Briales A, Díaz de Alba P, Calvo J, Pascual A. Smaqnr, a new chromosome-encoded quinolone resistance determinant in Serratia marcescens. J Antimicrob Chemother. 2010;65:239-42 pubmed publisher
    A new pentapeptide repeat (PRP) protein, named SmaQnr, from the clinically relevant species Serratia marcescens, which decreased susceptibility to quinolones when expressed in Escherichia coli, is reported herein.
  47. Zhang L, Yang Y, Sun J, Shen Y, Wei D, Zhu J, et al. Microbial production of 2,3-butanediol by a mutagenized strain of Serratia marcescens H30. Bioresour Technol. 2010;101:1961-7 pubmed publisher
    The production of 2,3-butanediol (2,3-BD) by Serratia marcescens H30 from sucrose was studied. Medium composition for 2,3-BD production by S...
  48. Shanks R, Stella N, Arena K, Fender J. Mutation of crp mediates Serratia marcescens serralysin and global secreted protein production. Res Microbiol. 2013;164:38-45 pubmed publisher
    The bacterial species Serratia marcescens secretes both beneficial and cytotoxic proteins. Here we report that a crp mutant exhibited elevated secreted protease activity...
  49. Léon G, Roy P. Potential role of group IIC-attC introns in integron cassette formation. J Bacteriol. 2009;191:6040-51 pubmed publisher
    ..ma.I2 intron from the genome of a clinical isolate of Serratia marcescens can target both attC site and putative terminator motifs of resistance genes...
  50. Wang S, Peng J, Liang T, Liu K. Purification and characterization of a chitosanase from Serratia marcescens TKU011. Carbohydr Res. 2008;343:1316-23 pubmed publisher
    A chitosanase was purified from the culture supernatant of Serratia marcescens TKU011 with shrimp shell wastes as the sole carbon/nitrogen source...
  51. Zakariassen H, Aam B, Horn S, Vårum K, Sørlie M, Eijsink V. Aromatic residues in the catalytic center of chitinase A from Serratia marcescens affect processivity, enzyme activity, and biomass converting efficiency. J Biol Chem. 2009;284:10610-7 pubmed publisher
    The processive Serratia marcescens chitinases A (ChiA) and B (ChiB) are thought to degrade chitin in the opposite directions...
  52. Begic S, Worobec E. Characterization of the Serratia marcescens SdeCDE multidrug efflux pump studied via gene knockout mutagenesis. Can J Microbiol. 2008;54:411-6 pubmed publisher
    b>Serratia marcescens is an important nosocomial agent having high antibiotic resistance. A major mechanism for S. marcescens antibiotic resistance is active efflux. To ascertain the substrate specificity of the S...
  53. Srikannathasan V, English G, Bui N, Trunk K, O Rourke P, Rao V, et al. Structural basis for type VI secreted peptidoglycan DL-endopeptidase function, specificity and neutralization in Serratia marcescens. Acta Crystallogr D Biol Crystallogr. 2013;69:2468-82 pubmed publisher
    ..Here, the peptidoglycan endopeptidase specificity of two type VI secretion-system-associated effectors from Serratia marcescens is characterized...
  54. Shanks R, Stella N, Lahr R, Wang S, Veverka T, Kowalski R, et al. Serratamolide is a hemolytic factor produced by Serratia marcescens. PLoS ONE. 2012;7:e36398 pubmed publisher
    b>Serratia marcescens is a common contaminant of contact lens cases and lenses. Hemolytic factors of S. marcescens contribute to the virulence of this opportunistic bacterial pathogen...
  55. Vijaya Nadaraja A, Gangadharan Puthiya Veetil P, Bhaskaran K. Perchlorate reduction by an isolated Serratia marcescens strain under high salt and extreme pH. FEMS Microbiol Lett. 2013;339:117-21 pubmed publisher
    An isolated Serratia marcescens strain exhibited growth-coupled perchlorate (ClO4 -) reduction under anoxic conditions. Perchlorate was reduced completely with stoichiometric chloride buildup and equimolar acetate consumption...
  56. Kuo P, Kuo C, Lai Y, Graumann P, Tu J. Phosphate limitation induces the intergeneric inhibition of Pseudomonas aeruginosa by Serratia marcescens isolated from paper machines. FEMS Microbiol Ecol. 2013;84:577-87 pubmed publisher
    ..Intergeneric inhibition of Pseudomonas aeruginosa WW5 by Serratia marcescens WW4 was identified under phosphate-limited conditions, but not in Luria-Bertani medium or M9 minimal medium...
  57. Nehme N, Liegeois S, Kele B, Giammarinaro P, Pradel E, Hoffmann J, et al. A model of bacterial intestinal infections in Drosophila melanogaster. PLoS Pathog. 2007;3:e173 pubmed
    b>Serratia marcescens is an entomopathogenic bacterium that opportunistically infects a wide range of hosts, including humans...
  58. Arslan U, Erayman I, Kirdar S, Yuksekkaya S, Cimen O, Tuncer I, et al. Serratia marcescens sepsis outbreak in a neonatal intensive care unit. Pediatr Int. 2010;52:208-12 pubmed publisher
    ..Many organisms have been reported to cause contamination resulting in outbreaks in intensive care units. The aim of the present study was to investigate an outbreak caused by Serratia marcescens in a neonatal intensive care unit (NICU).
  59. Létoffé S, Delepelaire P, Wandersman C. Functional differences between heme permeases: Serratia marcescens HemTUV permease exhibits a narrower substrate specificity (restricted to heme) than the Escherichia coli DppABCDF peptide-heme permease. J Bacteriol. 2008;190:1866-70 pubmed publisher
    b>Serratia marcescens hemTUV genes encoding a potential heme permease were cloned in Escherichia coli recombinant mutant FB827 dppF::Km(pAM 238-hasR)...
  60. Maragakis L, Winkler A, Tucker M, Cosgrove S, Ross T, Lawson E, et al. Outbreak of multidrug-resistant Serratia marcescens infection in a neonatal intensive care unit. Infect Control Hosp Epidemiol. 2008;29:418-23 pubmed publisher
    b>Serratia marcescens causes healthcare-associated infections and significant morbidity and mortality in neonatal intensive care units (NICUs). We report the investigation and control of an outbreak of multidrug-resistant (MDR) S...
  61. Quiroga C, Roy P, Centron D. The S.ma.I2 class C group II intron inserts at integron attC sites. Microbiology. 2008;154:1341-53 pubmed publisher
    We previously found the class C S.ma.I2 group II (GII) intron in Serratia marcescens SCH909 inserted into the variable region of a class 1 integron within the attC site of the ant(2'')-Ia gene cassette...
  62. Sutherland K, Porter J, Turner J, Thomas B, Looney E, Luna T, et al. Human sewage identified as likely source of white pox disease of the threatened Caribbean elkhorn coral, Acropora palmata. Environ Microbiol. 2010;12:1122-31 pubmed publisher
    ..In 2002, we identified the faecal enterobacterium, Serratia marcescens, as an etiological agent for white pox. During outbreaks in 2003 a unique strain of S...
  63. Kuwahara T, Shimono K, Kaneda S, Tamura T, Ichihara M, Nakashima Y. Growth of microorganisms in total parenteral nutrition solutions containing lipid. Int J Med Sci. 2010;7:101-9 pubmed
    ..nutrition (TPN) solutions, we investigated the growth of the major causes of catheter-related blood stream infection (Staphylococcus aureus, Serratia marcescens, Bacillus cereus, and Candida albicans) in TPN solutions containing lipid.
  64. de Araújo H, Fukushima K, Takaki G. Prodigiosin production by Serratia marcescens UCP 1549 using renewable-resources as a low cost substrate. Molecules. 2010;15:6931-40 pubmed publisher
    A new strain of Serratia marcescens UCP1459 isolated from a semi-arid soil produced the natural red pigment prodigiosin, characterized by an uncommon pyrrolylpyrromethane skeleton...
  65. Genes C, Baquero E, Echeverri F, Maya J, Triana O. Mitochondrial dysfunction in Trypanosoma cruzi: the role of Serratia marcescens prodigiosin in the alternative treatment of Chagas disease. Parasit Vectors. 2011;4:66 pubmed publisher
    ..Prodigiosin, produced by Serratia marcescens (Rhodnius prolixus endosymbiont), belongs to the red-pigmented bacterial prodiginine family, which displays ..
  66. Ligozzi M, Fontana R, Aldegheri M, Scalet G, Lo Cascio G. Comparative evaluation of an automated repetitive-sequence-based PCR instrument versus pulsed-field gel electrophoresis in the setting of a Serratia marcescens nosocomial infection outbreak. J Clin Microbiol. 2010;48:1690-5 pubmed publisher
    ..was evaluated in comparison with pulsed-field gel electrophoresis (PFGE) to investigate an outbreak of Serratia marcescens infections in a neonatal intensive care unit (NICU)...
  67. Butler M, Wang Q, Harshey R. Cell density and mobility protect swarming bacteria against antibiotics. Proc Natl Acad Sci U S A. 2010;107:3776-81 pubmed publisher
    ..This work has relevance to the adaptive antibiotic resistance of bacterial biofilms...
  68. Moraes C, Seabra S, Castro D, Brazil R, de Souza W, Garcia E, et al. Leishmania (Leishmania) chagasi interactions with Serratia marcescens: ultrastructural studies, lysis and carbohydrate effects. Exp Parasitol. 2008;118:561-8 pubmed publisher
    Studies on the lysis of L. chagasi caused by the bacteria Serratia marcescens were carried out. In vitro experiments demonstrated that S...
  69. Shimuta K, Ohnishi M, Iyoda S, Gotoh N, Koizumi N, Watanabe H. The hemolytic and cytolytic activities of Serratia marcescens phospholipase A (PhlA) depend on lysophospholipid production by PhlA. BMC Microbiol. 2009;9:261 pubmed publisher
    b>Serratia marcescens is a gram-negative bacterium and often causes nosocomial infections. There have been few studies of the virulence factors of this bacterium. The only S...
  70. Fritsch M, Trunk K, Diniz J, Guo M, Trost M, Coulthurst S. Proteomic identification of novel secreted antibacterial toxins of the Serratia marcescens type VI secretion system. Mol Cell Proteomics. 2013;12:2735-49 pubmed publisher
    ..quot;Antibacterial" T6SSs, such as the one elaborated by the opportunistic human pathogen, Serratia marcescens, confer on the secreting bacterium the ability to rapidly and efficiently kill rival bacteria...
  71. Kadouri D, Shanks R. Identification of a methicillin-resistant Staphylococcus aureus inhibitory compound isolated from Serratia marcescens. Res Microbiol. 2013;164:821-6 pubmed publisher
    In this study, we identified an antimicrobial compound produced by the Gram-negative bacterium Serratia marcescens. Colonies of S...
  72. Lancaster J, Mohammad B, Abebe E. Effect of the bacterium Serratia marcescens SCBI on the longevity and reproduction of the nematode Caenorhabditis briggsae KT0001. BMC Res Notes. 2012;5:688 pubmed publisher
    ..Explored associations vary vastly from mutualistic to parasitic. Serratia marcescens has been shown to be pathogenic to Caenorhabditis with a fitness cost...
  73. O Reilly L. A method for overcoming DNA degradation during PFGE for Serratia marcescens. J Microbiol Methods. 2011;85:173-4 pubmed publisher
    ..For a particular group of isolates of Serratia marcescens this method was unsuccessful. A combination of techniques was used to overcome the problem.
  74. Zhu H, Shen Y, Wei D, Zhu J. A novel quorum sensing system co-regulated by chromosome- and plasmid-encoded genes in Serratia marcescens H30. Mol Cell Biochem. 2008;319:87-90 pubmed publisher
    The key genes, SpnI and SpnR, involved in AI-1-quorum sensing system of Serratia marcescens strain H30 were cloned and localized using specific primers (5'-CTTGAACTGTTTGACGTCAGC-3' and 5'-AGCGGCCAGGTAATAACTGA-3', 5'-GCCTTCAATGAAAATCAGACC-..
  75. Sisirak M, Hukic M. An outbreak of multidrug-resistant Serratia marcescens: the importance of continuous monitoring of nosocomial infections. Acta Med Acad. 2013;42:25-31 pubmed publisher
    b>Serratia marcescens is a well-established as a nosocomial pathogen, resulting in considerable morbidity and mortality in immunocompromised patients...
  76. Ivanova D, Markovska R, Hadjieva N, Schneider I, Mitov I, Bauernfeind A. Extended-spectrum beta-lactamase-producing Serratia marcescens outbreak in a Bulgarian hospital. J Hosp Infect. 2008;70:60-5 pubmed publisher
    We describe a nosocomial outbreak of extended-spectrum beta-lactamase (ESBL)-producing Serratia marcescens in a Bulgarian university hospital affecting nine patients on four wards...
  77. Annapoorani A, Parameswari R, Pandian S, Ravi A. Methods to determine antipathogenic potential of phenolic and flavonoid compounds against urinary pathogen Serratia marcescens. J Microbiol Methods. 2012;91:208-11 pubmed publisher
    ..the antipathogenic potential of natural compounds present in the edible fruits against urinary pathogen Serratia marcescens by using quorum sensing inhibition (QSI)...
  78. Haddix P, Jones S, Patel P, Burnham S, Knights K, Powell J, et al. Kinetic analysis of growth rate, ATP, and pigmentation suggests an energy-spilling function for the pigment prodigiosin of Serratia marcescens. J Bacteriol. 2008;190:7453-63 pubmed publisher
    b>Serratia marcescens is a gram-negative environmental bacterium and opportunistic pathogen. S. marcescens expresses prodigiosin, a bright red and cell-associated pigment which has no known biological function for producing cells...
  79. Rao V, Shepherd S, English G, Coulthurst S, Hunter W. The structure of Serratia marcescens Lip, a membrane-bound component of the type VI secretion system. Acta Crystallogr D Biol Crystallogr. 2011;67:1065-72 pubmed publisher
    ..The structure of a Lip construct (residues 29-176) from Serratia marcescens (SmLip) has been determined at 1.92 Å resolution...
  80. Wu Y, Zhu H, Willcox M, Stapleton F. Removal of biofilm from contact lens storage cases. Invest Ophthalmol Vis Sci. 2010;51:6329-33 pubmed publisher
    ..This in vitro study aimed to evaluate and compare the efficacy of cleaning practices that are most commonly carried out by lens wearers and recommended by practitioners...
  81. Horng Y, Chang K, Liu Y, Lai H, Soo P. The RssB/RssA two-component system regulates biosynthesis of the tripyrrole antibiotic, prodigiosin, in Serratia marcescens. Int J Med Microbiol. 2010;300:304-12 pubmed publisher
    b>Serratia marcescens CH-1 produces a red, cell-associated pigment, prodigiosin, synthesized by enzymes encoded in the pig operon...