klebsiella

Summary

Summary: A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria whose organisms arrange singly, in pairs, or short chains. This genus is commonly found in the intestinal tract and is an opportunistic pathogen that can give rise to bacteremia, pneumonia, urinary tract and several other types of human infection.

Top Publications

  1. Seki M, Gotoh K, Nakamura S, Akeda Y, Yoshii T, Miyaguchi S, et al. Fatal sepsis caused by an unusual Klebsiella species that was misidentified by an automated identification system. J Med Microbiol. 2013;62:801-3 pubmed publisher
    This is a description of fatal sepsis caused by infection with Klebsiella variicola, which is an isolate genetically related to Klebsiella pneumoniae. The patient's condition was incorrectly diagnosed as common sepsis caused by K...
  2. Lal P, Kapil A, Das B, Sood S. Occurrence of TEM & SHV gene in extended spectrum beta-lactamases (ESBLs) producing Klebsiella sp. isolated from a tertiary care hospital. Indian J Med Res. 2007;125:173-8 pubmed
    ..These enzymes have been derived from TEM and SHV genes by mutations and have been well described in Klebsiella pneumoniae. Information on molecular types of ESBL positive Klebsiella sp. is lacking from India...
  3. Manoharan A, Sugumar M, Kumar A, Jose H, Mathai D, Khilnani G, et al. Phenotypic & molecular characterization of AmpC ?-lactamases among Escherichia coli, Klebsiella spp. & Enterobacter spp. from five Indian Medical Centers. Indian J Med Res. 2012;135:359-64 pubmed
    ..We evaluated the presence of AmpC ?-lactamases among Enterobacteriaceae strains recovered prospectively from patients at five Indian tertiary care centres...
  4. Wang M, Cao B, Yu Q, Liu L, Gao Q, Wang L, et al. Analysis of the 16S-23S rRNA gene internal transcribed spacer region in Klebsiella species. J Clin Microbiol. 2008;46:3555-63 pubmed publisher
    The 16S-23S rRNA gene internal transcribed spacer (ITS) regions of Klebsiella spp., including Klebsiella pneumoniae subsp. pneumoniae, Klebsiella pneumoniae subsp. ozaenae, Klebsiella pneumoniae subsp...
  5. Drago L, Nicola L, Mattina R, De Vecchi E. In vitro selection of resistance in Escherichia coli and Klebsiella spp. at in vivo fluoroquinolone concentrations. BMC Microbiol. 2010;10:119 pubmed publisher
    ..ciprofloxacin and prulifloxacin at concentrations observed in vivo in twenty strains of Escherichia coli and Klebsiella spp. isolated from patients with respiratory and urinary infections...
  6. Turton J, Baklan H, Siu L, Kaufmann M, Pitt T. Evaluation of a multiplex PCR for detection of serotypes K1, K2 and K5 in Klebsiella sp. and comparison of isolates within these serotypes. FEMS Microbiol Lett. 2008;284:247-52 pubmed publisher
    ..synthesis gene cluster of serotypes K1, K2 and K5 was evaluated using the 77 reference serotype strains of Klebsiella, and a panel of clinical isolates subjected previously to conventional serotyping...
  7. Yang C, Li Y, Zhang K, Wang X, Ma C, Tang H, et al. Atrazine degradation by a simple consortium of Klebsiella sp. A1 and Comamonas sp. A2 in nitrogen enriched medium. Biodegradation. 2010;21:97-105 pubmed publisher
    A simple consortium consisted of two members of Klebsiella sp. A1 and Comamonas sp. A2 was isolated from the sewage of a pesticide mill in China. One member of Klebsiella sp...
  8. Chavan M, Rafi H, Wertz J, Goldstone C, Riley M. Phage associated bacteriocins reveal a novel mechanism for bacteriocin diversification in Klebsiella. J Mol Evol. 2005;60:546-56 pubmed publisher
    Ninety-six isolates of Klebsiella pneumoniae and K. oxytoca were recovered from wild mammals in Australia. 14.6% of these bacteria produce killing phenotypes that suggest the production of bacteriocin toxins...
  9. Hancock V, Dahl M, Klemm P. Abolition of biofilm formation in urinary tract Escherichia coli and Klebsiella isolates by metal interference through competition for fur. Appl Environ Microbiol. 2010;76:3836-41 pubmed publisher
    ..These results further support that iron uptake is indeed crucial for biofilm formation, and thereby, targeting these uptake systems might be an effective way to eradicate biofilms caused by infectious strains...

More Information

Publications74

  1. Schukken Y, Chuff M, Moroni P, Gurjar A, Santisteban C, Welcome F, et al. The "other" gram-negative bacteria in mastitis: Klebsiella, serratia, and more. Vet Clin North Am Food Anim Pract. 2012;28:239-56 pubmed publisher
    ..Experimental and field observations would suggest that among the gram-negative bacterial causes of mastitis, Klebsiella spp are causing the most severe cases, closely followed by E coli and then much less clinical severity is ..
  2. Doumith M, Ellington M, Livermore D, Woodford N. Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK. J Antimicrob Chemother. 2009;63:659-67 pubmed publisher
    ..study was to investigate relatedness and molecular mechanism(s) of ertapenem resistance in clinical isolates of Klebsiella spp. (n = 28) and Enterobacter spp...
  3. Simoliunas E, Kaliniene L, Truncaite L, Klausa V, Zajanckauskaite A, Meskys R. Genome of Klebsiella sp.-infecting bacteriophage vB_KleM_RaK2. J Virol. 2012;86:5406 pubmed publisher
    Despite the fact that multidrug-resistant Klebsiella sp. strains emerge rapidly (Xu J, et al., Adv. Mater. Res...
  4. Song K, Jeon J, Park W, Park S, Kim H, Oh M, et al. Clinical outcomes of spontaneous bacterial peritonitis due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: a retrospective matched case-control study. BMC Infect Dis. 2009;9:41 pubmed publisher
    Clinical outcomes of spontaneous bacterial peritonitis (SBP) due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species (ESBL-EK) have not been adequately investigated.
  5. Zadoks R, Griffiths H, Munoz M, Ahlstrom C, Bennett G, Thomas E, et al. Sources of Klebsiella and Raoultella species on dairy farms: be careful where you walk. J Dairy Sci. 2011;94:1045-51 pubmed publisher
    b>Klebsiella spp. are a common cause of mastitis, milk loss, and culling on dairy farms. Control of Klebsiella mastitis is largely based on prevention of exposure of the udder to the pathogen...
  6. Baig A, Gujral M, Hameed R, Borra S. Klebsiella ozaenae cholecystitis. Am J Med Sci. 2011;342:259-61 pubmed publisher
    The authors report a case of Klebsiella ozaenae septicemia, cholecystitis and urinary tract infection in a 65-year-old morbidly obese woman with diabetes...
  7. Boo N, Ng S, Lim V. A case-control study of risk factors associated with rectal colonization of extended-spectrum beta-lactamase producing Klebsiella sp. in newborn infants. J Hosp Infect. 2005;61:68-74 pubmed
    To determine the risk factors for rectal colonization by extended-spectrum beta-lactamase (ESBL) Klebsiella sp...
  8. Böhm K, Herter T, Müller J, Borriss R, Heinemann U. Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme. FEBS J. 2010;277:1284-96 pubmed publisher
    The extracellular phytase of the plant-associated Klebsiella sp. ASR1 is a member of the histidine-acid-phosphatase family and acts primarily as a scavenger of phosphate groups locked in the phytic acid molecule...
  9. Kohner P, Robberts F, Cockerill F, Patel R. Cephalosporin MIC distribution of extended-spectrum-{beta}-lactamase- and pAmpC-producing Escherichia coli and Klebsiella species. J Clin Microbiol. 2009;47:2419-25 pubmed publisher
    ..We correlated the distribution of the MICs for Klebsiella spp...
  10. Li Y, Yin J, Qu G, Lv L, Li Y, Yang S, et al. Gene cloning, protein purification, and enzymatic properties of multicopper oxidase, from Klebsiella sp. 601. Can J Microbiol. 2008;54:725-33 pubmed publisher
    A gene encoding a putative multicopper oxidase (MCO) was cloned from the soil bacterium Klebsiella sp. 601 and its corresponding enzyme was overexpressed in an Escherichia coli strain. Klebsiella sp...
  11. Mandal A, Yadav K, Sen I, Kumar A, Chakraborti S, Islam S, et al. Partial characterization and flocculating behavior of an exopolysaccharide produced in nutrient-poor medium by a facultative oligotroph Klebsiella sp. PB12. J Biosci Bioeng. 2013;115:76-81 pubmed publisher
    ..The selected strain was identified by 16S rRNA gene sequencing and designated as Klebsiella sp. PB12. Phylogenetic analysis showed its closest relationship with Klebsiella variicola ATCC BAA-830(T)...
  12. Ambrozic Avgustin J, Keber R, Zerjavic K, Orazem T, Grabnar M. Emergence of the quinolone resistance-mediating gene aac(6')-Ib-cr in extended-spectrum-beta-lactamase-producing Klebsiella isolates collected in Slovenia between 2000 and 2005. Antimicrob Agents Chemother. 2007;51:4171-3 pubmed
    ..uropathogenic fluoroquinolone-resistant or -intermediate extended-spectrum-beta-lactamase-producing Klebsiella isolates from Slovenia were screened for the presence of plasmid-mediated quinolone resistance genes...
  13. Rastegar Lari A, Azimi L, Rahbar M, Fallah F, Alaghehbandan R. Phenotypic detection of Klebsiella pneumoniae carbapenemase among burns patients: first report from Iran. Burns. 2013;39:174-6 pubmed publisher
    Resistance to antimicrobial agents such as carbapenems among enterobacteriacea has been increasing, especially in Klebsiella pneumonia that produces variety of enzymes including Klebsiella pneumoniae carbapenemase (KPC)...
  14. Morrissey I, Bouchillon S, Hackel M, Biedenbach D, Hawser S, Hoban D, et al. Evaluation of the Clinical and Laboratory Standards Institute phenotypic confirmatory test to detect the presence of extended-spectrum ?-lactamases from 4005 Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae and Proteus mirabilis isolates. J Med Microbiol. 2014;63:556-61 pubmed publisher
    A subset of Escherichia coli, Klebsiella oxytoca, Klebsiella pneumoniae and Proteus mirabilis isolates collected for the Study for Monitoring Antimicrobial Resistance Trends that were positive for the Clinical and Laboratory Standards ..
  15. Romero E, Padilla T, Hernández A, Grande R, Vázquez M, García I, et al. Prevalence of clinical isolates of Escherichia coli and Klebsiella spp. producing multiple extended-spectrum beta-lactamases. Diagn Microbiol Infect Dis. 2007;59:433-7 pubmed
    Eleven thousand two hundred seventy-two Escherichia coli, 1109 Klebsiella pneumoniae, 1124 Salmonella enterica, and 602 Klebsiella oxytoca unrelated clinical isolates were obtained between 2001 and 2004 in a university hospital in ..
  16. Ryberg A, Olsson C, Ahrne S, Monstein H. Comparison of (GTG)5-oligonucleotide and ribosomal intergenic transcribed spacer (ITS)-PCR for molecular typing of Klebsiella isolates. J Microbiol Methods. 2011;84:183-8 pubmed publisher
    Molecular typing of Klebsiella species has become important for monitoring dissemination of ?-lactamase-producers in hospital environments...
  17. Sader H, Hsiung A, Fritsche T, Jones R. Comparative activities of cefepime and piperacillin/tazobactam tested against a global collection of Escherichia coli and Klebsiella spp. with an ESBL phenotype. Diagn Microbiol Infect Dis. 2007;57:341-4 pubmed
    ..A total of 50,637 clinical isolates (34,367 Escherichia coli and 16,270 Klebsiella spp...
  18. Velaphi S, Wadula J, Nakwa F. Mortality rate in neonates infected with extended-spectrum beta lactamase-producing Klebsiella species and selective empirical use of meropenem. Ann Trop Paediatr. 2009;29:101-10 pubmed publisher
    ..Infection with resistant gram-negative bacteria is a growing threat to hospitalised patients...
  19. Munoz M, Bennett G, Ahlstrom C, Griffiths H, Schukken Y, Zadoks R. Cleanliness scores as indicator of Klebsiella exposure in dairy cows. J Dairy Sci. 2008;91:3908-16 pubmed publisher
    ..was designed to explore the relationship between cow and udder cleanliness scores and the risk of isolation of Klebsiella spp. from lower hind legs and teat ends, respectively...
  20. Song W, Bae I, Lee Y, Lee C, Lee S, Jeong S. Detection of extended-spectrum beta-lactamases by using boronic acid as an AmpC beta-lactamase inhibitor in clinical isolates of Klebsiella spp. and Escherichia coli. J Clin Microbiol. 2007;45:1180-4 pubmed
    ..A total of 182 clinical isolates of Klebsiella spp...
  21. Sarma P. Klebsiella ozaenae splenic abscess following odontogenic infection in a girl with sickle cell disease. Int J Infect Dis. 2007;11:86-7 pubmed
  22. Lee S, Lee S, Kim S, Park I, Lee Y, Chung S, et al. Characterization of new biosurfactant produced by Klebsiella sp. Y6-1 isolated from waste soybean oil. Bioresour Technol. 2008;99:2288-92 pubmed
    ..It was identified as Klebsiella sp. Y6-1 by analysis of 16S rRNA gene...
  23. Guet Revillet H, Le Monnier A, Breton N, Descamps P, Lecuyer H, Alaabouche I, et al. Environmental contamination with extended-spectrum ?-lactamases: is there any difference between Escherichia coli and Klebsiella spp?. Am J Infect Control. 2012;40:845-8 pubmed publisher
    ..We aimed to assess the rate of environmental contamination in rooms occupied by ESBL carriers or infected children and to identify risk factors associated with contamination...
  24. Ghosh M, Pathak S, Ganguli A. Effective removal of Cryptosporidium by a novel bioflocculant. Water Environ Res. 2009;81:160-4 pubmed
    Extracellular biopolymer produced from Klebsiella terrigena was found to have excellent flocculating ability over a wide range of colloid particles (0.5 to 25micro)...
  25. Song W, Jeong S, Kim J, Kim H, Shin D, Roh K, et al. Use of boronic acid disk methods to detect the combined expression of plasmid-mediated AmpC beta-lactamases and extended-spectrum beta-lactamases in clinical isolates of Klebsiella spp., Salmonella spp., and Proteus mirabilis. Diagn Microbiol Infect Dis. 2007;57:315-8 pubmed
    ..A total of 122 Klebsiella spp., Salmonella spp...
  26. Chen W, Nie Y, Xu Y. Signal peptide-independent secretory expression and characterization of pullulanase from a newly isolated Klebsiella variicola SHN-1 in Escherichia coli. Appl Biochem Biotechnol. 2013;169:41-54 pubmed publisher
    ..By sequencing its 16S rDNA, the isolate was identified as Klebsiella variicola SHN-1...
  27. Kjerulf A, Hansen D, Sandvang D, Hansen F, Frimodt Møller N. The prevalence of ESBL-producing E. coli and Klebsiella strains in the Copenhagen area of Denmark. APMIS. 2008;116:118-24 pubmed publisher
    The main purpose of the study was to investigate the frequency of ESBL-producing E. coli and Klebsiella strains in the Greater Copenhagen area. Four collections of strains were investigated: A) 380 consecutive E...
  28. Tenover F, Emery S, Spiegel C, Bradford P, Eells S, Endimiani A, et al. Identification of plasmid-mediated AmpC beta-lactamases in Escherichia coli, Klebsiella spp., and proteus species can potentially improve reporting of cephalosporin susceptibility testing results. J Clin Microbiol. 2009;47:294-9 pubmed publisher
    ..Fifty-three isolates of Escherichia coli, 21 Klebsiella species, and 6 Proteus species that were resistant to at least one ESC were tested by disk diffusion with ..
  29. Seid J, Asrat D. Occurrence of extended spectrum beta-lactamase enzymes in clinical isolates of Klebsiella species from Harar region, eastern Ethiopia. Acta Trop. 2005;95:143-8 pubmed
    Extended Spectrum beta-Lactamases (ESBLs) producer and multidrug resistant Klebsiella spp. are becoming a major nosocomial pathogen globally. There are no documented reports yet on the occurrence of ESBL enzymes in Klebsiella spp...
  30. Sajjan S, Kulkarni G, Yaligara V, Kyoung L, Karegoudar T. Purification and physiochemical characterization of melanin pigment from Klebsiella sp. GSK. J Microbiol Biotechnol. 2010;20:1513-20 pubmed
    ..melanin pigment in the presence of L-tyrosine was isolated from crop field soil sample and identified as Klebsiella sp. GSK based on morphological, biochemical and 16S rDNA sequencing...
  31. Xia X, Cao X, Liang P, Huang X, Yang S, Zhao G. Electricity generation from glucose by a Klebsiella sp. in microbial fuel cells. Appl Microbiol Biotechnol. 2010;87:383-90 pubmed publisher
    ..In this study, a new electrochemically active bacterium, Klebsiella sp. ME17, was employed into an "H" typed MFC for electrogenesis, with glucose as the electron donor...
  32. Wu P, Liu Y, Wang Z, Zhang X, Li H, Liang W, et al. Molecular cloning, purification, and biochemical characterization of a novel pyrethroid-hydrolyzing esterase from Klebsiella sp. strain ZD112. J Agric Food Chem. 2006;54:836-42 pubmed
    The gene encoding pyrethroid-hydrolyzing esterase (EstP) from Klebsiella sp. strain ZD112 was cloned into Escherichia coli and sequenced...
  33. Nawaz M, Khan S, Tran Q, Sung K, Khan A, Adamu I, et al. Isolation and characterization of multidrug-resistant Klebsiella spp. isolated from shrimp imported from Thailand. Int J Food Microbiol. 2012;155:179-84 pubmed publisher
    A study was undertaken to isolate and characterize tetracycline and nalidixic acid-resistant Klebsiella spp. in farm-raised, imported shrimp sold in the United States. Sixty-seven multiple antibiotic-resistant Klebsiella spp...
  34. Kanj S, Corkill J, Kanafani Z, Araj G, Hart C, Jaafar R, et al. Molecular characterisation of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella spp. isolates at a tertiary-care centre in Lebanon. Clin Microbiol Infect. 2008;14:501-4 pubmed publisher
    ..genes among extended-spectrum beta-lactamase (ESBL)-producing clinical isolates of Escherichia coli (n = 50) and Klebsiella spp. (n = 50) from Lebanon was 96%, 57% and 67%, and 40%, 82% and 84%, respectively...
  35. Qiang L, Yumei L, Sheng H, Yingzi L, Dongxue S, Dake H, et al. Optimization of fermentation conditions and properties of an exopolysaccharide from Klebsiella sp. H-207 and application in adsorption of hexavalent chromium. PLoS ONE. 2013;8:e53542 pubmed publisher
    The novel exopolysaccharide HZ-7 is produced by Klebsiella sp. H-207, and its fermentation conditions were optimized by response surface methodology (RSM). In this study, the optimized medium consisted of sucrose 31.93 g/L, KNO(3) 2...
  36. Boer J, Quiroz Valenzuela S, Anderson K, Hausinger R. Mutagenesis of Klebsiella aerogenes UreG to probe nickel binding and interactions with other urease-related proteins. Biochemistry. 2010;49:5859-69 pubmed publisher
    UreG is a GTPase required for assembly of the nickel-containing active site of urease. Herein, a Strep-tagged Klebsiella aerogenes UreG (UreG(Str)) and selected site-directed variants of UreG(Str) were constructed for studying the in vivo ..
  37. Jain A, Mondal R. Prevalence & antimicrobial resistance pattern of extended spectrum beta-lactamase producing Klebsiella spp isolated from cases of neonatal septicaemia. Indian J Med Res. 2007;125:89-94 pubmed
    Extended spectrum beta-lactamase (ESBL) producing Klebsiella spp led to serious concern about septicaemic neonates in neonatal intensive care units (NICU) due to high resistance against commonly used antimicrobial agents...
  38. Coudron P. Inhibitor-based methods for detection of plasmid-mediated AmpC beta-lactamases in Klebsiella spp., Escherichia coli, and Proteus mirabilis. J Clin Microbiol. 2005;43:4163-7 pubmed
    Non-beta-lactam inhibitor-based methods were evaluated for detecting plasmid-mediated AmpC beta-lactamases in Klebsiella spp., Escherichia coli, and Proteus mirabilis...
  39. Jain A, Mondal R. TEM & SHV genes in extended spectrum beta-lactamase producing Klebsiella species beta their antimicrobial resistance pattern. Indian J Med Res. 2008;128:759-64 pubmed
    ..We investigated the presence of TEM and SHV genes in ESBL producing Klebsiella spp. and their antimicrobial resistance pattern in cases of neonatal septicaemia in a tertiary care hospital.
  40. Huang S, Lee M, Leu H. Bacteremia due to extended-spectrum beta-lactamase-producing Enterobacteriaceae other than Escherichia coli and Klebsiella. J Microbiol Immunol Infect. 2006;39:496-502 pubmed
    ..of choice for the treatment of serious infections caused by extended-spectrum beta-lactamase (ESBL)-producing Klebsiella and Escherichia coli...
  41. Alves M, Dias R, de Castro A, Riley L, Moreira B. Identification of clinical isolates of indole-positive and indole-negative Klebsiella spp. J Clin Microbiol. 2006;44:3640-6 pubmed
    ..species have limitations and may have contributed to the taxonomic complexity recently reported for the genus Klebsiella. The objective of the present study was to apply a simple biochemical test panel to classify a collection of ..
  42. Verdet C, Benzerara Y, Gautier V, Adam O, Ould Hocine Z, Arlet G. Emergence of DHA-1-producing Klebsiella spp. in the Parisian region: genetic organization of the ampC and ampR genes originating from Morganella morganii. Antimicrob Agents Chemother. 2006;50:607-17 pubmed publisher
    Eleven Klebsiella pneumoniae clinical isolates and one Klebsiella oxytoca clinical isolate showing various pulsed-field gel electrophoresis types and producing an inducible DHA-1 class C beta-lactamase were isolated in the Parisian region ..
  43. Wu K, Saratale G, Lo Y, Chen W, Tseng Z, Chang M, et al. Simultaneous production of 2,3-butanediol, ethanol and hydrogen with a Klebsiella sp. strain isolated from sewage sludge. Bioresour Technol. 2008;99:7966-70 pubmed publisher
    A Klebsiella sp. HE1 strain isolated from hydrogen-producing sewage sludge was examined for its ability to produce H2 and other valuable soluble metabolites (e.g., ethanol and 2,3-butanediol) from sucrose-based medium...
  44. Pitout J, Le P, Moore K, Church D, Gregson D. Detection of AmpC beta-lactamases in Escherichia coli, Klebsiella spp., Salmonella spp. and Proteus mirabilis in a regional clinical microbiology laboratory. Clin Microbiol Infect. 2010;16:165-70 pubmed publisher
    ..are currently no standardized diagnostic tests available for the reliable detection of AmpC beta-lactamases in Klebsiella spp., Escherichia coli, Proteus mirabilis and Salmonella spp...
  45. Wener K, Schechner V, Gold H, Wright S, Carmeli Y. Treatment with fluoroquinolones or with beta-lactam-beta-lactamase inhibitor combinations is a risk factor for isolation of extended-spectrum-beta-lactamase-producing Klebsiella species in hospitalized patients. Antimicrob Agents Chemother. 2010;54:2010-6 pubmed publisher
    ..of various antibiotics as risk factors for the isolation of extended-spectrum-beta-lactamase (ESBL)-producing Klebsiella spp. in hospitalized patients at a tertiary-care hospital...
  46. Xu J, Li W, Chen X, Zhou Y. Klebsiella alba sp. nov., a novel pesticide-tolerant bacterium from a heavily polluted environment. J Gen Appl Microbiol. 2010;56:241-7 pubmed
    ..Phylogenetic analysis and chemotaxonomic characteristics revealed that strain CW-D 3(T) belongs to the genus Klebsiella. Its closest phylogenetic neighbors were K. singaporensis (strain LX3(T)), three subspecies of K...
  47. Akujobi C. Antimicrobial susceptibility pattern of Klebsiella species from Ebonyi State University Teaching Hospital Abakaliki, Nigeria. Niger J Clin Pract. 2005;8:90-3 pubmed
    ..600 specimens processed in the routine Medical Microbiology laboratory of EBSUTH, of which 245(6.8%) yielded Klebsiella species, with 84 from out - patients and 161 from in - patients...
  48. Woodford N, Reddy S, Fagan E, Hill R, Hopkins K, Kaufmann M, et al. Wide geographic spread of diverse acquired AmpC beta-lactamases among Escherichia coli and Klebsiella spp. in the UK and Ireland. J Antimicrob Chemother. 2007;59:102-5 pubmed
    To determine the distribution of acquired AmpC beta-lactamases in 173 isolates of Escherichia coli and Klebsiella spp. submitted to the UK's national reference laboratory for antibiotic resistance.
  49. Kim J, Lautenbach E, Chu J, Goyal M, Nachamkin I, McGowan K, et al. Fluoroquinolone resistance in pediatric bloodstream infections because of Escherichia coli and Klebsiella species. Am J Infect Control. 2008;36:70-3 pubmed publisher
    ..28-83.8). A case control study revealed no significant risk factors (including prior antibiotic use) for FQ resistance among ESBL E coli and Klebsiella species (ESBL-EK).
  50. Bleich A, Kirsch P, Sahly H, Fahey J, Smoczek A, Hedrich H, et al. Klebsiella oxytoca: opportunistic infections in laboratory rodents. Lab Anim. 2008;42:369-75 pubmed publisher
    ..This study was conducted to evaluate the role of Klebsiella oxytoca as an opportunistic pathogen in laboratory rodents. Therefore, K...
  51. Woodford N, Dallow J, Hill R, Palepou M, Pike R, Ward M, et al. Ertapenem resistance among Klebsiella and Enterobacter submitted in the UK to a reference laboratory. Int J Antimicrob Agents. 2007;29:456-9 pubmed
    ..We investigated ertapenem-resistant clinical isolates of Klebsiella spp. and Enterobacter spp. referred to the UK's national reference laboratory for antibiotic resistance...
  52. Dolejska M, Frolkova P, Florek M, Jamborova I, Purgertova M, Kutilova I, et al. CTX-M-15-producing Escherichia coli clone B2-O25b-ST131 and Klebsiella spp. isolates in municipal wastewater treatment plant effluents. J Antimicrob Chemother. 2011;66:2784-90 pubmed publisher
    ..Treated wastewater was sampled daily over a 45 day period from the outflow of a municipal wastewater treatment plant in Brno, Czech Republic, and examined for extended-spectrum ?-lactamase (ESBL)-producing bacteria...
  53. Skippen I, Shemko M, Turton J, Kaufmann M, Palmer C, Shetty N. Epidemiology of infections caused by extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella spp.: a nested case-control study from a tertiary hospital in London. J Hosp Infect. 2006;64:115-23 pubmed
    ..coli and Klebsiella spp. were recruited...
  54. Abhilash K, Veeraraghavan B, Abraham O. Epidemiology and outcome of bacteremia caused by extended spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella spp. in a tertiary care teaching hospital in south India. J Assoc Physicians India. 2010;58 Suppl:13-7 pubmed
    ..Therefore, it is imperative to quantify the problem, and reinforce guidelines promoting appropriate antibiotic use...
  55. Pochapsky T, Pochapsky S, Ju T, Hoefler C, Liang J. A refined model for the structure of acireductone dioxygenase from Klebsiella ATCC 8724 incorporating residual dipolar couplings. J Biomol NMR. 2006;34:117-27 pubmed
    Acireductone dioxygenase (ARD) from Klebsiella ATCC 8724 is a metalloenzyme that is capable of catalyzing different reactions with the same substrates (acireductone and O2) depending upon the metal bound in the active site...
  56. Yuan P, Meng K, Wang Y, Luo H, Shi P, Huang H, et al. A protease-resistant exo-polygalacturonase from Klebsiella sp. Y1 with good activity and stability over a wide pH range in the digestive tract. Bioresour Technol. 2012;123:171-6 pubmed publisher
    ..In the present study an exo-polygalacturonase gene (pgu B) was cloned from Klebsiella sp. Y1 CGMCC 4433 and expressed in Escherichia coli BL21 (DE3)...
  57. Durmaz R, Otlu B, Koksal F, Hosoglu S, Ozturk R, Ersoy Y, et al. The optimization of a rapid pulsed-field gel electrophoresis protocol for the typing of Acinetobacter baumannii, Escherichia coli and Klebsiella spp. Jpn J Infect Dis. 2009;62:372-7 pubmed
    ..the present study, we optimized a PFGE protocol for subtyping of Acinetobacter baumannii, Escherichia coli and Klebsiella spp., which are commonly isolated from nosocomial infections in many hospitals...
  58. Anandan S, Thomas N, Veeraraghavan B, Jana A. Prevalence of extended- spectrum beta-lactamase producing Escherichia coli and Klebsiella spp in a neonatal intensive care unit. Indian Pediatr. 2009;46:1106-7 pubmed
    This study reports the prevalence of extended-spectrum b-lactamase producing Escherichia coli and Klebsiella spp among septicemic neonates. Over a five year period, there were 94 isolates of Klebsiella spp and E .coli. Of these, 68 (72...
  59. Ghanem I, Orfi M, Shamma M. Biodegradation of chlorpyrifos by Klebsiella sp. isolated from an activated sludge sample of waste water treatment plant in Damascus. Folia Microbiol (Praha). 2007;52:423-7 pubmed
    ..The isolation of Klebsiella sp. was facilitated by the addition of CPY at a rate of 3.84 g/L of sludge weekly (selection pressure)...
  60. Hanberger H, Burman L, Cars O, Erlandsson M, Gill H, Nilsson L, et al. Low antibiotic resistance rates in Staphylococcus aureus, Escherichia coli and Klebsiella spp but not in Enterobacter spp and Pseudomonas aeruginosa: a prospective observational study in 14 Swedish ICUs over a 5-year period. Acta Anaesthesiol Scand. 2007;51:937-41 pubmed
    ..We report prospective data on antibiotic use and bacterial resistance from 14 academic and non-academic ICUs, participating in the ICU-STRAMA programme 1999-2003...
  61. Ofek Shlomai N, Benenson S, Ergaz Z, Peleg O, Braunstein R, Bar Oz B. Gastrointestinal colonization with ESBL-producing Klebsiella in preterm babies--is vancomycin to blame?. Eur J Clin Microbiol Infect Dis. 2012;31:567-70 pubmed publisher
    ..between treatment with vancomycin and colonization with extended-spectrum beta-lactamase (ESBL)-producing Klebsiella in our neonatal intensive care unit (NICU)...
  62. Donnarumma F, Indorato C, Mastromei G, Goti E, Nicoletti P, Pecile P, et al. Molecular analysis of population structure and antibiotic resistance of Klebsiella isolates from a three-year surveillance program in Florence hospitals, Italy. Eur J Clin Microbiol Infect Dis. 2012;31:371-8 pubmed publisher
    We report the results of a three-year surveillance program of Klebsiella spp. in six hospitals in Florence (Italy). A total of 172 Klebsiella isolates were identified and typed by AFLP: 122 were K. pneumoniae and 50 were K. oxytoca...
  63. Bhavnani S, Ambrose P, Craig W, Dudley M, Jones R. Outcomes evaluation of patients with ESBL- and non-ESBL-producing Escherichia coli and Klebsiella species as defined by CLSI reference methods: report from the SENTRY Antimicrobial Surveillance Program. Diagn Microbiol Infect Dis. 2006;54:231-6 pubmed
    ..Using data from centers with confirmed ESBL- and non-ESBL-producing Escherichia coli and Klebsiella species isolates in North America, Latin America, and Europe, potential risk factors for the occurrence of ..
  64. McCuddin Z, Carlson S, Rasmussen M, Franklin S. Klebsiella to Salmonella gene transfer within rumen protozoa: implications for antibiotic resistance and rumen defaunation. Vet Microbiol. 2006;114:275-84 pubmed
    ..In this study, RPz were assessed as sites of gene transfer between two bacterial species, Salmonella and Klebsiella. One Klebsiella isolate carried a plasmid bearing bla(CMY-2), encoding an extended-spectrum beta-lactamase ..
  65. DeRyke C, Kuti J, Nicolau D. Pharmacodynamic target attainment of six beta-lactams and two fluoroquinolones against Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Klebsiella species collected from United States intensive care units in 2004. Pharmacotherapy. 2007;27:333-42 pubmed
    ..To determine the likelihood that antibiotic regimens achieve bactericidal pharmacodynamic exposures against common nosocomial pathogens...