enterotoxigenic escherichia coli


Summary: Strains of ESCHERICHIA COLI that produce or contain at least one member of either heat-labile or heat-stable ENTEROTOXINS. The organisms colonize the mucosal surface of the small intestine and elaborate their enterotoxins causing DIARRHEA. They are mainly associated with tropical and developing countries and affect susceptible travelers to those places.

Top Publications

  1. Liu J, Silapong S, Jeanwattanalert P, Lertsehtakarn P, Bodhidatta L, Swierczewski B, et al. Multiplex real time PCR panels to identify fourteen colonization factors of enterotoxigenic Escherichia coli (ETEC). PLoS ONE. 2017;12:e0176882 pubmed publisher
    b>Enterotoxigenic Escherichia coli (ETEC) is a leading cause of childhood diarrhea in low income countries and in travelers to those areas...
  2. Duan Q, Zhang W. Genetic fusion protein 3×STa-ovalbumin is an effective coating antigen in ELISA to titrate anti-STa antibodies. Microbiol Immunol. 2017;61:251-257 pubmed publisher
  3. Kreuzer S, Reissmann M, Brockmann G. Gene test to elucidate the ETEC F4ab/F4ac receptor status in pigs. Vet Microbiol. 2013;162:293-5 pubmed publisher
  4. Njoroge S, Boinett C, Madé L, Ouko T, Fèvre E, Thomson N, et al. A putative, novel coli surface antigen 8B (CS8B) of enterotoxigenic Escherichia coli. Pathog Dis. 2015;73: pubmed publisher
    b>Enterotoxigenic Escherichia coli (ETEC) strains harbor multiple fimbriae and pili to mediate host colonization, including the type IVb pilus, colonization factor antigen III (CFA/III)...
  5. Jennings M, Tilley D, Ballard S, Villanueva M, Costa F, Lopez M, et al. Case-Case Analysis Using 7 Years of Travelers' Diarrhea Surveillance Data: Preventive and Travel Medicine Applications in Cusco, Peru. Am J Trop Med Hyg. 2017;96:1097-1106 pubmed publisher
    ..Preventive interventions, such as vaccines, directed against these pathogens could significantly reduce the burden of TD. ..
  6. Zhang Z, Lai S, Yu J, Yang W, Wang X, Jing H, et al. [Epidemiological characteristics of diarrheagenic Escherichia coli among diarrhea outpatients in China, 2012-2015]. Zhonghua Liu Xing Bing Xue Za Zhi. 2017;38:419-423 pubmed publisher
    ..3%????????????etec??653??21.9%???????25~34???????????????dec????????????10.1%?11.1%?9.4%?dec???????????????????????? ??? dec?????????????????????eaec?epec?etec?????????????????????????????. ..
  7. Sheikh A, Rashu R, Begum Y, Kuhlman F, Ciorba M, Hultgren S, et al. Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions. PLoS Negl Trop Dis. 2017;11:e0005586 pubmed publisher
    b>Enterotoxigenic Escherichia coli (ETEC), defined by their elaboration of heat-labile (LT) and/or heat-stable (ST) enterotoxins, are a common cause of diarrheal illness in developing countries...
  8. Yan Y, Hu Y, Simpson D, Ganzle M. Enzymatic Synthesis and Purification of Galactosylated Chitosan Oligosaccharides Reducing Adhesion of Enterotoxigenic Escherichia coli K88. J Agric Food Chem. 2017;65:5142-5150 pubmed publisher
    b>Enterotoxigenic Escherichia coli (ETEC) K88 causes diarrhea in weaned piglets and represent a suitable model system for ETEC causing childhood diarrhea...
  9. Kern M, Günzel D, Aschenbach J, Tedin K, Bondzio A, Lodemann U. Altered Cytokine Expression and Barrier Properties after In Vitro Infection of Porcine Epithelial Cells with Enterotoxigenic Escherichia coli and Probiotic Enterococcus faecium. Mediators Inflamm. 2017;2017:2748192 pubmed publisher
    ..05). These findings indicate a protective effect of the probiotic E. faecium on inflammatory responses during infection with ETEC. ..

More Information


  1. Savarino S, McKenzie R, Tribble D, Porter C, O Dowd A, Cantrell J, et al. Prophylactic Efficacy of Hyperimmune Bovine Colostral Antiadhesin Antibodies Against Enterotoxigenic Escherichia coli Diarrhea: A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial. J Infect Dis. 2017;216:7-13 pubmed publisher
    ..b>Enterotoxigenic Escherichia coli (ETEC) commonly elaborate colonization factors comprising a minor tip adhesin and major stalk-forming ..
  2. Zeinalzadeh N, Salmanian A, Goujani G, Amani J, Ahangari G, Akhavian A, et al. A Chimeric protein of CFA/I, CS6 subunits and LTB/STa toxoid protects immunized mice against enterotoxigenic Escherichia coli. Microbiol Immunol. 2017;61:272-279 pubmed publisher
    b>Enterotoxigenic Escherichia Coli (ETEC) strains are the commonest bacteria causing diarrhea in children in developing countries and travelers to these areas...
  3. Deng Y, Liu Y, Tang S, Zhou C, Han X, Xiao W, et al. General Machine Learning Model, Review, and Experimental-Theoretic Study of Magnolol Activity in Enterotoxigenic Induced Oxidative Stress. Curr Top Med Chem. 2017;17:2977-2988 pubmed publisher
    This study evaluated the antioxidative effects of magnolol based on the mouse model induced by Enterotoxigenic Escherichia coli (E. coli, ETEC). All experimental mice were equally treated with ETEC suspensions (3...