enterobacteriaceae

Summary

Summary: A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.

Top Publications

  1. Pitout J. Enterobacteriaceae that produce extended-spectrum ?-lactamases and AmpC ?-lactamases in the community: the tip of the iceberg?. Curr Pharm Des. 2013;19:257-63 pubmed
  2. Koga R, Moran N. Swapping symbionts in spittlebugs: evolutionary replacement of a reduced genome symbiont. ISME J. 2014;8:1237-46 pubmed publisher
    ..Although evolutionary replacements of ancient symbionts are infrequent, they potentially enable evolutionary and ecological novelty by conferring novel metabolic capabilities to host lineages. ..
  3. Cheng V, Chan J, Wong S, Chen J, Tai J, Yan M, et al. Proactive infection control measures to prevent nosocomial transmission of carbapenem-resistant Enterobacteriaceae in a non-endemic area. Chin Med J (Engl). 2013;126:4504-9 pubmed
    Identification of hospitalized carbapenem-resistant Enterobacteriaceae (CRE)-positive patient is important in preventing nosocomial transmission...
  4. Derde L, Cooper B, Goossens H, Malhotra Kumar S, Willems R, Gniadkowski M, et al. Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trial. Lancet Infect Dis. 2014;14:31-39 pubmed publisher
    ..We assessed interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in European ICUs...
  5. Lausch K, Fuursted K, Larsen C, Storgaard M. Colonisation with multi-resistant Enterobacteriaceae in hospitalised Danish patients with a history of recent travel: a cross-sectional study. Travel Med Infect Dis. 2013;11:320-3 pubmed publisher
    The global spread of multi-resistant Enterobacteriaceae is a new challenge in health care. Travelling in high endemic areas has been associated with colonisation...
  6. Farrell D, Flamm R, Sader H, Jones R. Antimicrobial activity of ceftolozane-tazobactam tested against Enterobacteriaceae and Pseudomonas aeruginosa with various resistance patterns isolated in U.S. Hospitals (2011-2012). Antimicrob Agents Chemother. 2013;57:6305-10 pubmed publisher
    ..and other common Gram-negative pathogens (including most extended-spectrum-?-lactamase [ESBL]-producing Enterobacteriaceae strains), and comparator agents were susceptibility tested by a reference broth microdilution method against ..
  7. Woerther P, Burdet C, Chachaty E, Andremont A. Trends in human fecal carriage of extended-spectrum ?-lactamases in the community: toward the globalization of CTX-M. Clin Microbiol Rev. 2013;26:744-58 pubmed publisher
    ..Only a better knowledge of its dynamics and biology will lead to further development of appropriate control measures...
  8. Tijet N, Boyd D, Patel S, Mulvey M, Melano R. Evaluation of the Carba NP test for rapid detection of carbapenemase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2013;57:4578-80 pubmed publisher
    The Carba NP test was evaluated against a panel of 244 carbapenemase- and non-carbapenemase-producing Enterobacteriaceae and Pseudomonas aeruginosa isolates...
  9. Zilberberg M, Shorr A. Prevalence of multidrug-resistant Pseudomonas aeruginosa and carbapenem-resistant Enterobacteriaceae among specimens from hospitalized patients with pneumonia and bloodstream infections in the United States from 2000 to 2009. J Hosp Med. 2013;8:559-63 pubmed publisher
    ..Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a pathogen of concern over the past decade.

More Information

Publications94

  1. Ohnishi M, Okatani A, Harada K, Sawada T, Marumo K, Murakami M, et al. Genetic characteristics of CTX-M-type extended-spectrum-?-lactamase (ESBL)-producing enterobacteriaceae involved in mastitis cases on Japanese dairy farms, 2007 to 2011. J Clin Microbiol. 2013;51:3117-22 pubmed publisher
    Sixty-five CTX-M-2/15/14 extended-spectrum-?-lactamase-producing Enterobacteriaceae were isolated from 258,888 mastitic milk samples from Japanese dairy farms between 2007 and 2011...
  2. Korzeniewska E, Harnisz M. Extended-spectrum beta-lactamase (ESBL)-positive Enterobacteriaceae in municipal sewage and their emission to the environment. J Environ Manage. 2013;128:904-11 pubmed publisher
    ..The aim of this study was to investigate the presence of ESBL-positive Enterobacteriaceae in municipal sewage and their emission to the ambient air and the river receiving effluent from wastewater ..
  3. Oakeson K, Gil R, Clayton A, Dunn D, Von Niederhausern A, Hamil C, et al. Genome degeneration and adaptation in a nascent stage of symbiosis. Genome Biol Evol. 2014;6:76-93 pubmed publisher
    ..Analyses of the bacterial cell envelope and genes encoding secretion systems suggest that these structures and elements have become simplified in the transition to a mutualistic association. ..
  4. Munoz Price L, Quinn J. Deconstructing the infection control bundles for the containment of carbapenem-resistant Enterobacteriaceae. Curr Opin Infect Dis. 2013;26:378-87 pubmed publisher
    Rates of carbapenem-resistant Enterobacteriaceae (CRE), especially Klebsiella pneumoniae carbapenemase (KPC)-producing Gram-negatives, have increased worldwide...
  5. Lewis J, Bishop M, Heon B, Mathers A, Enfield K, Sifri C. Admission surveillance for carbapenamase-producing Enterobacteriaceae at a long-term acute care hospital. Infect Control Hosp Epidemiol. 2013;34:832-4 pubmed publisher
    Carbapenemase-producing Enterobacteriaceae (CPE) are of increasing prevalence worldwide, and long-term acute care hospitals (LTACHs) have been implicated in several outbreaks in the United States...
  6. Pournaras S, Zarkotou O, Poulou A, Kristo I, Vrioni G, Themeli Digalaki K, et al. A combined disk test for direct differentiation of carbapenemase-producing enterobacteriaceae in surveillance rectal swabs. J Clin Microbiol. 2013;51:2986-90 pubmed publisher
    Carbapenemase-producing Enterobacteriaceae (CPE) are rapidly spreading worldwide. Early detection of fecal CPE carriers is essential for effective infection control...
  7. Raji M, Jamal W, Ojemhen O, Rotimi V. Point-surveillance of antibiotic resistance in Enterobacteriaceae isolates from patients in a Lagos Teaching Hospital, Nigeria. J Infect Public Health. 2013;6:431-7 pubmed publisher
    This study was carried out to determine a point prevalence of drug resistance and extended-spectrum ?-lactamase (ESBL) among members of the family Enterobacteriaceae.
  8. Obeng Nkrumah N, Twum Danso K, Krogfelt K, Newman M. High levels of extended-spectrum beta-lactamases in a major teaching hospital in Ghana: the need for regular monitoring and evaluation of antibiotic resistance. Am J Trop Med Hyg. 2013;89:960-4 pubmed publisher
    ..This study reports on ESBL-producing Enterobacteriaceae as significant causes of infections and antibiotic resistance at Korle-Bu Teaching Hospital in Accra, Ghana...
  9. Lupo A, Papp Wallace K, Sendi P, Bonomo R, Endimiani A. Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae. Diagn Microbiol Infect Dis. 2013;77:179-94 pubmed publisher
    In the past 2 decades, we have observed a rapid increase of infections due to multidrug-resistant Enterobacteriaceae. Regrettably, these isolates possess genes encoding for extended-spectrum ?-lactamases (e.g...
  10. Aschbacher R, Giani T, Corda D, Conte V, Arena F, Pasquetto V, et al. Carbapenemase-producing Enterobacteriaceae during 2011-12 in the Bolzano area (Northern Italy): increasing diversity in a low-endemicity setting. Diagn Microbiol Infect Dis. 2013;77:354-6 pubmed publisher
    The recent (2011-2012) distribution of carbapenemase determinants in Enterobacteriaceae was studied in the Bolzano area (Northern Italy). Low proportions of carbapenemase producers were found for Escherichia coli (0...
  11. Gude M, Seral C, Sáenz Y, Cebollada R, González Domínguez M, Torres C, et al. Molecular epidemiology, resistance profiles and clinical features in clinical plasmid-mediated AmpC-producing Enterobacteriaceae. Int J Med Microbiol. 2013;303:553-7 pubmed publisher
    ..Surveillance of these resistance mechanisms in the community is thus needed. Awareness of pAmpC dynamic is required to prevent introduction into hospitals and to control the spread of this emerging resistance within the community. ..
  12. Oteo J, Sáez D, Bautista V, Fernández Romero S, Hernández Molina J, Perez Vazquez M, et al. Carbapenemase-producing enterobacteriaceae in Spain in 2012. Antimicrob Agents Chemother. 2013;57:6344-7 pubmed publisher
    We report the epidemiological impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2012...
  13. Halpern M, Fridman S, Atamna Ismaeel N, Izhaki I. Rosenbergiella nectarea gen. nov., sp. nov., in the family Enterobacteriaceae, isolated from floral nectar. Int J Syst Evol Microbiol. 2013;63:4259-65 pubmed publisher
    ..flectens ATCC 12775(T) and lower similarity with sequences from other type strains of genera of the Enterobacteriaceae. A polyphasic approach that included determination of phenotypic properties and phylogenetic analysis based ..
  14. Palmore T, Henderson D. Managing transmission of carbapenem-resistant enterobacteriaceae in healthcare settings: a view from the trenches. Clin Infect Dis. 2013;57:1593-9 pubmed publisher
    ..In addition, the manuscript discusses some of the challenges associated with managing such an event, as well as a few of the unanticipated consequences associated with the aftermath of the case cluster. ..
  15. van der Wolf J, Nijhuis E, Kowalewska M, Saddler G, Parkinson N, Elphinstone J, et al. Dickeya solani sp. nov., a pectinolytic plant-pathogenic bacterium isolated from potato (Solanum tuberosum). Int J Syst Evol Microbiol. 2014;64:768-74 pubmed publisher
    ..nov. (type strain IPO 2222(T)?=?LMG25993(T)?=?NCPPB4479(T)) is proposed. ..
  16. Nordmann P, Dortet L, Poirel L. Carbapenem resistance in Enterobacteriaceae: here is the storm!. Trends Mol Med. 2012;18:263-72 pubmed publisher
    The current worldwide emergence of resistance to the powerful antibiotic carbapenem in Enterobacteriaceae constitutes an important growing public health threat...
  17. Huang X, Frye J, Chahine M, Glenn L, Ake J, Su W, et al. Characteristics of plasmids in multi-drug-resistant Enterobacteriaceae isolated during prospective surveillance of a newly opened hospital in Iraq. PLoS ONE. 2012;7:e40360 pubmed publisher
    ..In this study, all MDR Enterobacteriaceae (n = 38) and randomly selected non-MDR counterparts (n = 41) isolated from patients, healthcare workers and ..
  18. Dudley M, Ambrose P, Bhavnani S, Craig W, Ferraro M, Jones R. Background and rationale for revised clinical and laboratory standards institute interpretive criteria (Breakpoints) for Enterobacteriaceae and Pseudomonas aeruginosa: I. Cephalosporins and Aztreonam. Clin Infect Dis. 2013;56:1301-9 pubmed publisher
    Widespread resistance in Enterobacteriaceae and Pseudomonas aeruginosa to cephalosporin and monobactam antibiotics due to extended-spectrum ?-lactamases (ESBLs) has resulted in the need for reassessment of the interpretative criteria (..
  19. Arnoldo L, Migliavacca R, Regattin L, Raglio A, Pagani L, Nucleo E, et al. Prevalence of urinary colonization by extended spectrum-beta-lactamase Enterobacteriaceae among catheterised inpatients in Italian long term care facilities. BMC Infect Dis. 2013;13:124 pubmed publisher
    ..patients with catheter were screened, 185 out of 211 patients showed positive samples for the presence of Enterobacteriaceae, 114 of these 185 patients were colonized by extended spectrum cephalosporins resistant microorganisms...
  20. Pfeifer Y, Schlatterer K, Engelmann E, Schiller R, Frangenberg H, Stiewe D, et al. Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals. Antimicrob Agents Chemother. 2012;56:2125-8 pubmed publisher
    Nine carbapenem-resistant Enterobacteriaceae isolates collected from eight patients in five German hospitals were investigated...
  21. Rakotonirina H, Garin B, Randrianirina F, Richard V, Talarmin A, Arlet G. Molecular characterization of multidrug-resistant extended-spectrum ?-lactamase-producing Enterobacteriaceae isolated in Antananarivo, Madagascar. BMC Microbiol. 2013;13:85 pubmed publisher
    ..the molecular characteristics of multidrug-resistant, extended-spectrum ?-lactamase (ESBL)-producing Enterobacteriaceae isolated in community settings and in hospitals in Antananarivo, Madagascar. Forty-nine E. coli, K...
  22. Gu S, Kelly G, Wang X, Frenkiel T, Shevchik V, Pickersgill R. Solution structure of homology region (HR) domain of type II secretion system. J Biol Chem. 2012;287:9072-80 pubmed publisher
    ..The HR domain is shown to interact with the N0 domain of the secretin. The importance of this interaction is explored in the context of the functional secretion system. ..
  23. Vardakas K, Tansarli G, Rafailidis P, Falagas M. Carbapenems versus alternative antibiotics for the treatment of bacteraemia due to Enterobacteriaceae producing extended-spectrum ?-lactamases: a systematic review and meta-analysis. J Antimicrob Chemother. 2012;67:2793-803 pubmed publisher
    ..and alternative antibiotics for the treatment of patients with extended-spectrum ?-lactamase (ESBL)-positive Enterobacteriaceae bacteraemia...
  24. Mata C, Miro E, Alvarado A, Garcillán Barcia M, Toleman M, Walsh T, et al. Plasmid typing and genetic context of AmpC ?-lactamases in Enterobacteriaceae lacking inducible chromosomal ampC genes: findings from a Spanish hospital 1999-2007. J Antimicrob Chemother. 2012;67:115-22 pubmed publisher
    ..We examined the genetic context of 117 acquired ampC genes from 27119 Enterobacteriaceae collected between 1999 and 2007...
  25. Hommais F, Zghidi Abouzid O, Oger Desfeux C, Pineau Chapelle E, Van Gijsegem F, Nasser W, et al. lpxC and yafS are the most suitable internal controls to normalize real time RT-qPCR expression in the phytopathogenic bacteria Dickeya dadantii. PLoS ONE. 2011;6:e20269 pubmed publisher
    ..Here, we propose a set of reference genes, of the phytopathogenic bacteria Dickeya dadantii and Pectobacterium atrosepticum, which are stable in a wide range of growth conditions...
  26. Seth Smith H, Fookes M, Okoro C, Baker S, Harris S, Scott P, et al. Structure, diversity, and mobility of the Salmonella pathogenicity island 7 family of integrative and conjugative elements within Enterobacteriaceae. J Bacteriol. 2012;194:1494-504 pubmed publisher
    ..We aimed to identify and fully analyze ICEs related to SPI-7 within the genus Salmonella and other Enterobacteriaceae. We report the sequence of two novel SPI-7-like elements, found within strains of Salmonella bongori, which ..
  27. Clayton A, Oakeson K, Gutin M, Pontes A, Dunn D, Von Niederhausern A, et al. A novel human-infection-derived bacterium provides insights into the evolutionary origins of mutualistic insect-bacterial symbioses. PLoS Genet. 2012;8:e1002990 pubmed publisher
    ..They also elucidate the role of degenerative evolutionary processes in shaping the gene inventories of symbiotic bacteria at a very early stage in these mutualistic associations. ..
  28. Oostdijk E, de Smet A, Kesecioglu J, Bonten M. Decontamination of cephalosporin-resistant Enterobacteriaceae during selective digestive tract decontamination in intensive care units. J Antimicrob Chemother. 2012;67:2250-3 pubmed
    Prevalences of cephalosporin-resistant Enterobacteriaceae are increasing globally, especially in intensive care units (ICUs)...
  29. Lynch J, Clark N, Zhanel G. Evolution of antimicrobial resistance among Enterobacteriaceae (focus on extended spectrum ?-lactamases and carbapenemases). Expert Opin Pharmacother. 2013;14:199-210 pubmed publisher
    Bacteria within the family Enterobacteriaceae are important pathogens in nosocomial and community settings. Over the past two decades, antimicrobial resistance among Enterobacteriaceae dramatically escalated worldwide...
  30. Husník F, Chrudimský T, Hypsa V. Multiple origins of endosymbiosis within the Enterobacteriaceae (?-Proteobacteria): convergence of complex phylogenetic approaches. BMC Biol. 2011;9:87 pubmed publisher
    The bacterial family Enterobacteriaceae gave rise to a variety of symbiotic forms, from the loosely associated commensals, often designated as secondary (S) symbionts, to obligate mutualists, called primary (P) symbionts...
  31. Doyle D, Peirano G, Lascols C, Lloyd T, Church D, Pitout J. Laboratory detection of Enterobacteriaceae that produce carbapenemases. J Clin Microbiol. 2012;50:3877-80 pubmed publisher
    ..MBL) Etest, and in-house multiplex PCR for the detection of well-characterized carbapenemase-producing Enterobacteriaceae. One hundred forty-two nonrepeat clinical isolates of carbapenemase-producing Enterobacteriaceae (including ..
  32. Wiskirchen D, Crandon J, Furtado G, Williams G, Nicolau D. In vivo efficacy of a human-simulated regimen of ceftaroline combined with NXL104 against extended-spectrum-beta-lactamase (ESBL)-producing and non-ESBL-producing Enterobacteriaceae. Antimicrob Agents Chemother. 2011;55:3220-5 pubmed publisher
    ..Ceftaroline exhibits in vitro activity against extended-spectrum ?-lactamase (ESBL)-, AmpC-, and KPC-producing Enterobacteriaceae when combined with the novel ?-lactamase inhibitor NXL104...
  33. Thiebaut A, Arlet G, Andremont A, Papy E, Sollet J, Bernede Bauduin C, et al. Variability of intestinal colonization with third-generation cephalosporin-resistant Enterobacteriaceae and antibiotic use in intensive care units. J Antimicrob Chemother. 2012;67:1525-36 pubmed publisher
    Healthcare-associated infections due to third-generation cephalosporin-resistant Enterobacteriaceae (CRE) have become a major public health threat, especially in intensive care units (ICUs)...
  34. Carattoli A. Plasmids in Gram negatives: molecular typing of resistance plasmids. Int J Med Microbiol. 2011;301:654-8 pubmed publisher
    ..Particular plasmid families are more frequently detected among Enterobacteriaceae and play a major role in the diffusion of specific resistance genes...
  35. Weiss B, Maltz M, Aksoy S. Obligate symbionts activate immune system development in the tsetse fly. J Immunol. 2012;188:3395-403 pubmed publisher
    ..Our finding that molecular components of Wigglesworthia exhibit immunostimulatory activity within tsetse is representative of a novel evolutionary adaptation that steadfastly links an obligate symbiont with its host...
  36. Nordmann P, Poirel L, Dortet L. Rapid detection of carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis. 2012;18:1503-7 pubmed publisher
    To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem...
  37. Adriaenssens E, Van Vaerenbergh J, Vandenheuvel D, Dunon V, Ceyssens P, De Proft M, et al. T4-related bacteriophage LIMEstone isolates for the control of soft rot on potato caused by 'Dickeya solani'. PLoS ONE. 2012;7:e33227 pubmed publisher
    ..These results form the basis for the development of a bacteriophage-based biocontrol of potato plants and tubers as an alternative for the use of antibiotics. ..
  38. Schwaiger K, Huther S, Hölzel C, Kämpf P, Bauer J. Prevalence of antibiotic-resistant enterobacteriaceae isolated from chicken and pork meat purchased at the slaughterhouse and at retail in Bavaria, Germany. Int J Food Microbiol. 2012;154:206-11 pubmed publisher
    ..Therefore, stringent hygiene measures should be observed to reduce the risk of transmission of resistant bacteria from food to humans. ..
  39. Saavedra M, Dias C, Martínez Murcia A, Bennett R, Aires A, Rosa E. Antibacterial effects of glucosinolate-derived hydrolysis products against enterobacteriaceae and enterococci isolated from pig ileum segments. Foodborne Pathog Dis. 2012;9:338-45 pubmed publisher
    ..the effects of various glucosinolate-derived hydrolysis products (HP) as antibacterial compounds against Enterobacteriaceae and Enterococcaceae isolated from intestinal segments of healthy pigs collected directly from slaughter-..
  40. Babujee L, Apodaca J, Balakrishnan V, Liss P, Kiley P, Charkowski A, et al. Evolution of the metabolic and regulatory networks associated with oxygen availability in two phytopathogenic enterobacteria. BMC Genomics. 2012;13:110 pubmed publisher
    ..transcriptional response to O2 limitation demonstrates the extent of regulatory divergence prevalent in the Enterobacteriaceae. Our orthology-driven comparative transcriptomics approach indicates that the adaptive response in the ..
  41. Livermore D, Mushtaq S, Morinaka A, Ida T, Maebashi K, Hope R. Activity of carbapenems with ME1071 (disodium 2,3-diethylmaleate) against Enterobacteriaceae and Acinetobacter spp. with carbapenemases, including NDM enzymes. J Antimicrob Chemother. 2013;68:153-8 pubmed publisher
    ME1071 is a maleic acid that inhibits metallo-?-lactamases (MBLs). We examined its ability to potentiate different carbapenems against MBL-producing Enterobacteriaceae in relation to its inhibition kinetics.
  42. Gu S, Rehman S, Wang X, Shevchik V, Pickersgill R. Structural and functional insights into the pilotin-secretin complex of the type II secretion system. PLoS Pathog. 2012;8:e1002531 pubmed publisher
    ..Data collected from crystals of the complex suggests how the secretin peptide binds to the pilotin and further experiments confirm the importance of these C-terminal residues in vivo. ..
  43. Domenech de Cellès M, Zahar J, Abadie V, Guillemot D. Limits of patient isolation measures to control extended-spectrum beta-lactamase-producing Enterobacteriaceae: model-based analysis of clinical data in a pediatric ward. BMC Infect Dis. 2013;13:187 pubmed publisher
    Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) are a growing concern in hospitals and the community. How to control the nosocomial ESBL-E transmission is a matter of debate...
  44. van der Bij A, Pitout J. The role of international travel in the worldwide spread of multiresistant Enterobacteriaceae. J Antimicrob Chemother. 2012;67:2090-100 pubmed publisher
    ..The Enterobacteriaceae are among the most important causes of serious hospital-acquired and community-onset bacterial infections in ..
  45. Craig W, Andes D. In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum ?-lactamases, in the thighs of neutropenic mice. Antimicrob Agents Chemother. 2013;57:1577-82 pubmed publisher
    Ceftolozane is a new cephalosporin with potent activity against Pseudomonas aeruginosa and Enterobacteriaceae. A neutropenic murine thigh infection model was used to determine which pharmacokinetic/pharmacodynamic index and magnitude ..
  46. Silva Sanchez J, Barrios H, Reyna Flores F, Bello Diaz M, Sanchez Perez A, Rojas T, et al. Prevalence and characterization of plasmid-mediated quinolone resistance genes in extended-spectrum ?-lactamase-producing Enterobacteriaceae isolates in Mexico. Microb Drug Resist. 2011;17:497-505 pubmed publisher
    ..quinolone resistance genes in a collection of 226 extended-spectrum ?-lactamase (ESBL)-producing Enterobacteriaceae isolates and characterize the qnr-positive isolates. The rate of qnr-positive isolates was 21...
  47. Río Alvarez I, Rodríguez Herva J, Cuartas Lanza R, Toth I, Pritchard L, Rodriguez Palenzuela P, et al. Genome-wide analysis of the response of Dickeya dadantii 3937 to plant antimicrobial peptides. Mol Plant Microbe Interact. 2012;25:523-33 pubmed publisher
  48. Rossmann B, Müller H, Smalla K, Mpiira S, Tumuhairwe J, Staver C, et al. Banana-associated microbial communities in Uganda are highly diverse but dominated by Enterobacteriaceae. Appl Environ Microbiol. 2012;78:4933-41 pubmed publisher
    ..The dominant role of enterics can be explained by the permanent nature and vegetative propagation of banana and the amendments of human, as well as animal, manure in these traditional cultivations...
  49. Williamson D, Sidjabat H, Freeman J, Roberts S, Silvey A, Woodhouse R, et al. Identification and molecular characterisation of New Delhi metallo-?-lactamase-1 (NDM-1)- and NDM-6-producing Enterobacteriaceae from New Zealand hospitals. Int J Antimicrob Agents. 2012;39:529-33 pubmed publisher
    ..This study sought to determine whether bla(NDM) was present in Enterobacteriaceae isolates displaying resistance to carbapenems that were submitted to the National Antibiotic Reference ..
  50. Tschudin Sutter S, Frei R, Dangel M, Stranden A, Widmer A. Rate of transmission of extended-spectrum beta-lactamase-producing enterobacteriaceae without contact isolation. Clin Infect Dis. 2012;55:1505-11 pubmed publisher
    Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae are emerging worldwide. Contact isolation is recommended; however, little is known about the rate of transmission without contact isolation in the non-epidemic setting...
  51. Teo J, Cai Y, Tang S, Lee W, Tan T, Tan T, et al. Risk factors, molecular epidemiology and outcomes of ertapenem-resistant, carbapenem-susceptible Enterobacteriaceae: a case-case-control study. PLoS ONE. 2012;7:e34254 pubmed publisher
    Increasing prevalence of ertapenem-resistant, carbapenem-susceptible Enterobacteriaceae (ERE) in Singapore presents a major therapeutic problem...
  52. Davies T, Marie Queenan A, Morrow B, Shang W, Amsler K, He W, et al. Longitudinal survey of carbapenem resistance and resistance mechanisms in Enterobacteriaceae and non-fermenters from the USA in 2007-09. J Antimicrob Chemother. 2011;66:2298-307 pubmed publisher
    Antibiotic resistance is problematic in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter baumannii, and is often associated with serious infections...
  53. Berçot B, Poirel L, Dortet L, Nordmann P. In vitro evaluation of antibiotic synergy for NDM-1-producing Enterobacteriaceae. J Antimicrob Chemother. 2011;66:2295-7 pubmed publisher
    ..To analyse the in vitro activity of colistin, fosfomycin and tigecycline alone or in combination against enterobacterial NDM-1 producers...
  54. Maraki S, Samonis G, Karageorgopoulos D, Mavros M, Kofteridis D, Falagas M. In vitro antimicrobial susceptibility to isepamicin of 6,296 Enterobacteriaceae clinical isolates collected at a tertiary care university hospital in Greece. Antimicrob Agents Chemother. 2012;56:3067-73 pubmed publisher
    ..We retrospectively evaluated the antimicrobial susceptibility to isepamicin of Enterobacteriaceae sp...
  55. Thierry M, Becker N, Hajri A, Reynaud B, Lett J, Delatte H. Symbiont diversity and non-random hybridization among indigenous (Ms) and invasive (B) biotypes of Bemisia tabaci. Mol Ecol. 2011;20:2172-87 pubmed publisher
    ..Taken together, our results suggest that Cardinium and/or Arsenophonus may manipulate the reproduction of indigenous (Ms) with invasive (B) biotypes of Bemisia tabaci...
  56. Rossi F. The challenges of antimicrobial resistance in Brazil. Clin Infect Dis. 2011;52:1138-43 pubmed publisher
    ..Carbapenem resistance among the enterobacteriaceae group is becoming a major problem, and K...
  57. Gazin M, Paasch F, Goossens H, Malhotra Kumar S. Current trends in culture-based and molecular detection of extended-spectrum-?-lactamase-harboring and carbapenem-resistant Enterobacteriaceae. J Clin Microbiol. 2012;50:1140-6 pubmed publisher
    The ever-expanding role of extended-spectrum-?-lactamase (ESBL)-harboring and carbapenem-resistant Enterobacteriaceae in causing serious infections poses a grave public health threat because these organisms also tend to be multidrug ..
  58. Perez F, van Duin D. Carbapenem-resistant Enterobacteriaceae: a menace to our most vulnerable patients. Cleve Clin J Med. 2013;80:225-33 pubmed publisher
    The emergence of carbapenem-resistant Enterobacteriaceae (CRE) highlights the importance of effective antibiotics to maintain the safety of our health care system...
  59. Crépin S, Harel J, Dozois C. Chromosomal complementation using Tn7 transposon vectors in Enterobacteriaceae. Appl Environ Microbiol. 2012;78:6001-8 pubmed publisher
    ..Furthermore, these vectors could also be used for the introduction of foreign genes for use in biotechnology applications, vaccine development, or gene expression and gene fusion constructs...
  60. Zhang S, Sun J, Liao X, Hu Q, Liu B, Fang L, et al. Prevalence and plasmid characterization of the qnrD determinant in Enterobacteriaceae isolated from animals, retail meat products, and humans. Microb Drug Resist. 2013;19:331-5 pubmed publisher
    ..We investigated the presence of qnrD among 1,373 Enterobacteriaceae isolates in China...
  61. Picão R, Cardoso J, Campana E, Nicoletti A, Petrolini F, Assis D, et al. The route of antimicrobial resistance from the hospital effluent to the environment: focus on the occurrence of KPC-producing Aeromonas spp. and Enterobacteriaceae in sewage. Diagn Microbiol Infect Dis. 2013;76:80-5 pubmed publisher
    ..We identified multidrug-resistant bacteria as well as KPC-2-producing Aeromonas spp. and several Enterobacteriaceae species, including Kluyvera spp., in the hospital effluent and in different sites of the WWTP...
  62. Diene S, Rolain J. Investigation of antibiotic resistance in the genomic era of multidrug-resistant Gram-negative bacilli, especially Enterobacteriaceae, Pseudomonas and Acinetobacter. Expert Rev Anti Infect Ther. 2013;11:277-96 pubmed publisher
    The increase and spread of multidrug-resistant (MDR) Gram-negative bacteria, including Enterobacteriaceae, Pseudomonas and Acinetobacter species, have become major concerns worldwide...
  63. Toju H, Tanabe A, Notsu Y, Sota T, Fukatsu T. Diversification of endosymbiosis: replacements, co-speciation and promiscuity of bacteriocyte symbionts in weevils. ISME J. 2013;7:1378-90 pubmed publisher
    ..Comparison of these newcomer bacteriocyte-associated symbiont lineages highlights potential evolutionary trajectories and consequences of novel symbionts after independent replacements of the same ancient symbiont. ..
  64. Manageiro V, Ferreira E, Jones Dias D, Louro D, Pinto M, Diogo J, et al. Emergence and risk factors of ?-lactamase-mediated resistance to oxyimino-?-lactams in Enterobacteriaceae isolates. Diagn Microbiol Infect Dis. 2012;72:272-7 pubmed publisher
    We studied 193 Enterobacteriaceae isolates presenting diminished susceptibility to oxyimino-cephalosporins recovered in a Portuguese hospital (2004-2008)...
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    We determined the prevalence and characteristics of extended-spectrum ?-lactamase (ESBL) genes of Enterobacteriaceae in retail chicken meat and humans in the Netherlands...
  66. Khanna N, Boyes J, Lansdell P, Hamouda A, Amyes S. Molecular epidemiology and antimicrobial resistance pattern of extended-spectrum-?-lactamase-producing Enterobacteriaceae in Glasgow, Scotland. J Antimicrob Chemother. 2012;67:573-7 pubmed publisher
    To establish the molecular epidemiology and antimicrobial resistance pattern of extended-spectrum ?-lactamase (ESBL)-producing Enterobacteriaceae harbouring bla(CTX-M) in Glasgow, Scotland.
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    ..and Staphylococcus pseudintermedius (MRSP) as well as extended-spectrum beta-lactamases (ESBL)-producing Enterobacteriaceae in companion animals...
  68. Ram P, Jahid I, Halder A, Nygren B, Islam M, Granger S, et al. Variability in hand contamination based on serial measurements: implications for assessment of hand-cleansing behavior and disease risk. Am J Trop Med Hyg. 2011;84:510-6 pubmed publisher
    ..Because hand contamination measured at random cannot reliably predict hand contamination at times of potential pathogen transmission, single random hand rinses are not valid proxy measures for handwashing behavior...
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    ..replicon typing procedures have indicated that the prevalence of IncX plasmids is low among members of the Enterobacteriaceae. However, examination of a number of IncX-like plasmid sequences and their occurrence in various organisms ..
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    ..We investigated their prevalence and significance in clinical Enterobacteriaceae bacteremic isolates in Hong Kong...
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    A commercial multiplex PCR (hyplex SuperBug ID) was tested with a collection of 132 clinical Enterobacteriaceae strains producing different carbapenemases...
  72. Chrudimský T, Husník F, Nováková E, Hypša V. Candidatus Sodalis melophagi sp. nov.: phylogenetically independent comparative model to the tsetse fly symbiont Sodalis glossinidius. PLoS ONE. 2012;7:e40354 pubmed publisher
    ..We propose the name Candidatus Sodalis melophagi for this new bacterium. ..
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    ..mechanisms were investigated in 206 clinical isolates of third-generation cephalosporin (3GC)-resistant Enterobacteriaceae in four hospitals in the Republic of Ireland. bla(CTX-M-15) was the predominant ESBL gene...
  74. Glupczynski Y, Huang T, Bouchahrouf W, Rezende de Castro R, Bauraing C, Gerard M, et al. Rapid emergence and spread of OXA-48-producing carbapenem-resistant Enterobacteriaceae isolates in Belgian hospitals. Int J Antimicrob Agents. 2012;39:168-72 pubmed publisher
    ..The majority of isolates co-produced several ?-lactamases as well as non-?-lactam resistance genes. This report highlights the rapid emergence and spread of OXA-48-producing Enterobacteriaceae in Belgium.
  75. Day K, Ali S, Mirza I, Sidjabat H, Silvey A, Lanyon C, et al. Prevalence and molecular characterization of Enterobacteriaceae producing NDM-1 carbapenemase at a military hospital in Pakistan and evaluation of two chromogenic media. Diagn Microbiol Infect Dis. 2013;75:187-91 pubmed publisher
    The aim of this study was to assess the frequency and genotypic diversity of carbapenemase-producing Enterobacteriaceae (CPE) in stool samples from patients attending a military hospital in Pakistan...
  76. Mathers A, Carroll J, Sifri C, Hazen K. Modified Hodge test versus indirect carbapenemase test: prospective evaluation of a phenotypic assay for detection of Klebsiella pneumoniae carbapenemase (KPC) in Enterobacteriaceae. J Clin Microbiol. 2013;51:1291-3 pubmed publisher
    The currently recommended phenotypic test for the detection of carbapenemase-producing members of the family Enterobacteriaceae is the modified Hodge test (MHT). However, the MHT lacks specificity...
  77. Sheng W, Badal R, Hsueh P. Distribution of extended-spectrum ?-lactamases, AmpC ?-lactamases, and carbapenemases among Enterobacteriaceae isolates causing intra-abdominal infections in the Asia-Pacific region: results of the study for Monitoring Antimicrobial Resistance Trends. Antimicrob Agents Chemother. 2013;57:2981-8 pubmed publisher
    The increasing trend of ?-lactam resistance among Enterobacteriaceae is a worldwide threat...
  78. Dolejska M, Brhelova E, Dobiasova H, Krivdova J, Juránková J, Sevčíková A, et al. Dissemination of IncFII(K)-type plasmids in multiresistant CTX-M-15-producing Enterobacteriaceae isolates from children in hospital paediatric oncology wards. Int J Antimicrob Agents. 2012;40:510-5 pubmed publisher
    In this study, extended-spectrum ?-lactamase (ESBL)-producing Enterobacteriaceae isolates in children with malignancies hospitalised at a paediatric oncology department in the Czech Republic were investigated...
  79. Jousselin E, Cœur d Acier A, Vanlerberghe Masutti F, Duron O. Evolution and diversity of Arsenophonus endosymbionts in aphids. Mol Ecol. 2013;22:260-70 pubmed publisher
    ..Notably, plants hosting aphids may be important ecological arenas for global exchange of Arsenophonus, serving as reservoirs for HT...
  80. Berçot B, Poirel L, Nordmann P. Updated multiplex polymerase chain reaction for detection of 16S rRNA methylases: high prevalence among NDM-1 producers. Diagn Microbiol Infect Dis. 2011;71:442-5 pubmed publisher
    ..This study particularly underlined that 16S rRNA methylases are frequently (75%) identified among Enterobacteriaceae isolates producing the carbapenemase NDM-1.
  81. Moran Gilad J, Carmeli Y, Schwartz D, Navon Venezia S. Laboratory evaluation of the CHROMagar KPC medium for identification of carbapenem-nonsusceptible Enterobacteriaceae. Diagn Microbiol Infect Dis. 2011;70:565-7 pubmed publisher
    ..pneumoniae (72.7% sensitivity). CHROMagar KPC appears applicable for processing carbapenem-resistant Enterobacteriaceae surveillance specimens, but its performance might possibly be suboptimal in the presence of KPC-negative ..
  82. Liebana E, Carattoli A, Coque T, Hasman H, Magiorakos A, Mevius D, et al. Public health risks of enterobacterial isolates producing extended-spectrum ?-lactamases or AmpC ?-lactamases in food and food-producing animals: an EU perspective of epidemiology, analytical methods, risk factors, and control options. Clin Infect Dis. 2013;56:1030-7 pubmed publisher
    The blaESBL and blaAmpC genes in Enterobacteriaceae are spread by plasmid-mediated integrons, insertion sequences, and transposons, some of which are homologous in bacteria from food animals, foods, and humans...
  83. Meyer E, Ziegler R, Mattner F, Schwab F, Gastmeier P, Martin M. Increase of patients co-colonised or co-infected with methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium or extended-spectrum ?-lactamase-producing Enterobacteriaceae. Infection. 2011;39:501-6 pubmed publisher
    ..co-colonised or co-infected with methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium or extended-spectrum ?-lactamase (ESBL)-producing Enterobacteriaceae in four German tertiary care hospitals.
  84. Patel N, Harrington S, Dihmess A, Woo B, Masoud R, Martis P, et al. Clinical epidemiology of carbapenem-intermediate or -resistant Enterobacteriaceae. J Antimicrob Chemother. 2011;66:1600-8 pubmed publisher
    Despite the increasing incidence of carbapenem-intermediate or -resistant Enterobacteriaceae (CIRE), risk factors associated with CIRE infections have not been well defined...
  85. Nordmann P, Gniadkowski M, Giske C, Poirel L, Woodford N, Miriagou V. Identification and screening of carbapenemase-producing Enterobacteriaceae. Clin Microbiol Infect. 2012;18:432-8 pubmed publisher
    ..They are mostly of the KPC, VIM, IMP, NDM and OXA-48 types. Their current extensive spread worldwide in Enterobacteriaceae is an important source of concern, as these carbapenemase producers are multidrug-resistant...