actinobacillus

Summary

Summary: A genus of PASTEURELLACEAE described as gram-negative, nonsporeforming, nonmotile, facultative anaerobes. Most members are found both as pathogens and commensal organisms in the respiratory, alimentary, and genital tracts of animals.

Top Publications

  1. Rycroft A, Garside L. Actinobacillus species and their role in animal disease. Vet J. 2000;159:18-36 pubmed
    b>Actinobacillus species are Gram-negative bacteria responsible for several quite distinct disease conditions of animals. The natural habitat of the organisms is primarily the upper respiratory tract and oral cavity. A...
  2. Christensen H, Bisgaard M, Angen O, Olsen J. Final classification of Bisgaard taxon 9 as Actinobacillus arthritidis sp. nov. and recognition of a novel genomospecies for equine strains of Actinobacillus lignieresii. Int J Syst Evol Microbiol. 2002;52:1239-46 pubmed
    ..of bacteria from diseased and healthy horses identified 18 isolates as Bisgaard taxon 9 and 11 isolates as Actinobacillus lignieresii...
  3. Saiki K, Gomi T, Konishi K. Deletion and purification studies to elucidate the structure of the Actinobacillus actinomycetemcomitans cytolethal distending toxin. J Biochem. 2004;136:335-42 pubmed
    Cytolethal distending toxin (CDT) is one of the exotoxins produced by Actinobacillus actinomycetemcomitans, an agent of localized aggressive periodontitis...
  4. Gröndahl G, Sternberg S, Jensen Waern M, Johannisson A. Opsonic capacity of foal serum for the two neonatal pathogens Escherichia coli and Actinobacillus equuli. Equine Vet J. 2001;33:670-5 pubmed
    Two of the most commonly isolated foal pathogens are Escherichia coli and Actinobacillus equuli. The hypothesis tested in this study was that young foals carry a lower opsonic capacity for these bacteria compared to adult horses...
  5. Kittichotirat W, Bumgarner R, Chen C. Markedly different genome arrangements between serotype a strains and serotypes b or c strains of Aggregatibacter actinomycetemcomitans. BMC Genomics. 2010;11:489 pubmed publisher
    ..actinomycetemcomitans. The distinct patterns of genome arrangement may suggest phenotypic differences between serotype a and serotypes b/c strains. ..
  6. Zou W, Zhu L, Li H, Tang Y. Significance of CO2 donor on the production of succinic acid by Actinobacillus succinogenes ATCC 55618. Microb Cell Fact. 2011;10:87 pubmed publisher
    ..PEP) carboxykinase, which are the important committed steps for the biosynthesis of succinic acid by Actinobacillus succinogenes...
  7. Li Q, Wang D, Wu Y, Yang M, Li W, Xing J, et al. Kinetic evaluation of products inhibition to succinic acid producers Escherichia coli NZN111, AFP111, BL21, and Actinobacillus succinogenes 130Z T. J Microbiol. 2010;48:290-6 pubmed publisher
    ..To evaluate the inhibitory effects of fermentation products on the growth of Actinobacillus succinogenes 130Z(T) and Escherichia coli NZN111, AFP111, BL21, fermentations with addition of individual ..
  8. Kachlany S, Fine D, Figurski D. Purification of secreted leukotoxin (LtxA) from Actinobacillus actinomycetemcomitans. Protein Expr Purif. 2002;25:465-71 pubmed
    ..The oral and systemic human pathogen Actinobacillus actinomycetemcomitans produces a member of this family known as leukotoxin (LtxA)...
  9. Zheng P, Fang L, Xu Y, Dong J, Ni Y, Sun Z. Succinic acid production from corn stover by simultaneous saccharification and fermentation using Actinobacillus succinogenes. Bioresour Technol. 2010;101:7889-94 pubmed publisher
    Simultaneous saccharification and fermentation (SSF) technique was applied for succinic acid production by Actinobacillus succinogenes in a 5-l stirred bioreactor with corn stover as the raw material...

More Information

Publications87

  1. Xi Y, Chen K, Dai W, Ma J, Zhang M, Jiang M, et al. Succinic acid production by Actinobacillus succinogenes NJ113 using corn steep liquor powder as nitrogen source. Bioresour Technol. 2013;136:775-9 pubmed publisher
    ..source to replace the relatively costly yeast extract typically used for the production of succinic acid with Actinobacillus succinogenes NJ113...
  2. Groenink J, Veerman E, Zandvoort M, van der Mei H, Busscher H, Nieuw Amerongen A. The interaction between saliva and Actinobacillus actinomycetemcomitans influenced by the zeta potential. Antonie Van Leeuwenhoek. 1998;73:279-88 pubmed
    The adhesion of Actinobacillus actinomycetemcomitans is a virulence factor in the aetiology of periodontitis and is determined by physico-chemical properties, e.g. surface charge and hydrophobicity, of the bacterial cell surface...
  3. Borges E, Pereira N. Succinic acid production from sugarcane bagasse hemicellulose hydrolysate by Actinobacillus succinogenes. J Ind Microbiol Biotechnol. 2011;38:1001-11 pubmed publisher
    ..We have attempted to maximize succinic acid production by Actinobacillus succinogenes using an experimental design methodology for optimizing the concentrations of the medium ..
  4. Christensen H, Bisgaard M, Olsen J. Reclassification of equine isolates previously reported as Actinobacillus equuli, variants of A. equuli, Actinobacillus suis or Bisgaard taxon 11 and proposal of A. equuli subsp. equuli subsp. nov. and A. equuli subsp. haemolyticus subsp. nov. Int J Syst Evol Microbiol. 2002;52:1569-76 pubmed
    ..0 and 99.7%. A single isolate that represented the so-called (+)L-arabinose-positive Actinobacillus equuli isolated from a diseased foal showed 99.9% 16S rRNA similarity to the type strain of A. equuli...
  5. Bahrami F, Ekins A, Niven D. Iron acquisition by Actinobacillus suis: identification and characterization of transferrin receptor proteins and encoding genes. Vet Microbiol. 2003;94:79-92 pubmed
    b>Actinobacillus suis is an important pathogen of swine, especially in high-health-status herds. A published report mentioning the binding of porcine transferrin (Tf) by at least one strain of A. suis suggested that A...
  6. Mittal K, Higgins R, Lariviere S. Serologic studies of Actinobacillus (Haemophilus) pleuropneumoniae strains of serotype-3 and their antigenic relationships with other A pleuropneumoniae serotypes in swine. Am J Vet Res. 1988;49:152-5 pubmed
    Serotype-3 strains of Actinobacillus (Haemophilus) pleuropneumoniae possess epitopes shared with almost all other Actinobacillus serotypes...
  7. Berthoud H, Frey J, Kuhnert P. Characterization of Aqx and its operon: the hemolytic RTX determinant of Actinobacillus equuli. Vet Microbiol. 2002;87:159-74 pubmed
    b>Actinobacillus equuli, a member of the family Pasteurellaceae is the etiologic agent of a frequently lethal septicemia in neonatal foals as well as other more chronic diseases like arthritis, pleuritis, pneumonia or peritonitis...
  8. Christensen H, Bisgaard M. Revised definition of Actinobacillus sensu stricto isolated from animals. A review with special emphasis on diagnosis. Vet Microbiol. 2004;99:13-30 pubmed
    The taxonomy of the members of the genus Actinobacillus associated with animals has been reviewed with focus on classification and identification including molecular based characterization, typing and identification...
  9. Sternberg S. Isolation of Actinobacillus equuli from the oral cavity of healthy horses and comparison of isolates by restriction enzyme digestion and pulsed-field gel electrophoresis. Vet Microbiol. 1998;59:147-56 pubmed
    Swab samples were collected from the oral cavity of 174 horses in 10 farms and cultured selectively for Actinobacillus equuli. A. equuli could be isolated from 37% of all samples, varying between 12 and 88% in the different farms...
  10. Donahue J, Sells S, Bolin D. Classification of Actinobacillus spp isolates from horses involved in mare reproductive loss syndrome. Am J Vet Res. 2006;67:1426-32 pubmed
    To identify Actinobacillus spp isolates recovered from fetuses and pericardial fluid from horses affected with mare reproductive loss syndrome (MRLS) and determine whether these bacterial species are the same as those isolated from ..
  11. Petti C, Bhally H, Weinstein M, Joho K, Wakefield T, Reller L, et al. Utility of extended blood culture incubation for isolation of Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella organisms: a retrospective multicenter evaluation. J Clin Microbiol. 2006;44:257-9 pubmed
    The incidence of and average time to detection for Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella (HACEK) bacteria in blood cultures with standard incubation and the utility of extended incubation of blood culture ..
  12. Urbance S, Pometto A, DiSpirito A, Denli Y. Evaluation of succinic acid continuous and repeat-batch biofilm fermentation by Actinobacillus succinogenes using plastic composite support bioreactors. Appl Microbiol Biotechnol. 2004;65:664-70 pubmed
    Continuous and repeat-batch biofilm fermentations using Actinobacillus succinogenes were performed with immobilized and suspended-cell systems...
  13. Xi Y, Chen K, Li J, Fang X, Zheng X, Sui S, et al. Optimization of culture conditions in CO2 fixation for succinic acid production using Actinobacillus succinogenes. J Ind Microbiol Biotechnol. 2011;38:1605-12 pubmed publisher
    The culture conditions in CO(2) fixation by Actinobacillus succinogenes for succinic acid production were investigated by a model of available CO(2) in a 3-l fermentor...
  14. Gottschalk M, Broes A, Mittal K, Kobisch M, Kuhnert P, Lebrun A, et al. Non-pathogenic Actinobacillus isolates antigenically and biochemically similar to Actinobacillus pleuropneumoniae: a novel species?. Vet Microbiol. 2003;92:87-101 pubmed
    Two unusual Actinobacillus isolates were recovered from pigs with no clinical signs, no lesions and no history of swine pleuropneumonia...
  15. de la Puente Redondo V, García del Blanco N, Perez Martinez C, González Rodríguez M, Rodriguez Ferri E, Gutiérrez Martín C. Isolation of Actinobacillus seminis from the genital tract of rams in spain. J Comp Pathol. 2000;122:217-22 pubmed
    b>Actinobacillus seminis isolates were cultured from the semen (two isolates) and the left testis (one isolate) of two one-year-old rams in León, Spain...
  16. Friis Møller A, Christensen J, Fussing V, Hesselbjerg A, Christiansen J, Bruun B. Clinical significance and taxonomy of Actinobacillus hominis. J Clin Microbiol. 2001;39:930-5 pubmed
    Clinical findings in 36 immunosuppressed patients with lower respiratory tract infection or bacteremia with Actinobacillus hominis are described...
  17. Chen K, Jiang M, Wei P, Yao J, Wu H. Succinic acid production from acid hydrolysate of corn fiber by Actinobacillus succinogenes. Appl Biochem Biotechnol. 2010;160:477-85 pubmed publisher
    Dilute acid hydrolysate of corn fiber was used as carbon source for the production of succinic acid by Actinobacillus succinogenes NJ113. The optimized hydrolysis conditions were obtained by orthogonal experiments...
  18. McKinlay J, Zeikus J, Vieille C. Insights into Actinobacillus succinogenes fermentative metabolism in a chemically defined growth medium. Appl Environ Microbiol. 2005;71:6651-6 pubmed
    ..to expand the experimental opportunities for investigating the fermentative metabolism of succinate-producing Actinobacillus succinogenes...
  19. Wang C, Zhu L, Li H, Tang Y. Performance analyses of a neutralizing agent combination strategy for the production of succinic acid by Actinobacillus succinogenes ATCC 55618. Bioprocess Biosyst Eng. 2012;35:659-64 pubmed publisher
    A neutralizing agent combination strategy was developed to enhance the succinic acid production by Actinobacillus succinogenes ATCC 55618. First, a maximal succinic acid production of 48.2 g/L was obtained at a culture pH of 7.5...
  20. Nørskov Lauritsen N, Kilian M. Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatib. Int J Syst Evol Microbiol. 2006;56:2135-46 pubmed
    The aim of this study was to reinvestigate the relationships and the generic affiliations of the species Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis...
  21. Ebersole J, Taubman M, Smith D, Genco R, Frey D. Human immune responses to oral micro-organisms. I. Association of localized juvenile periodontitis (LJP) with serum antibody responses to Actinobacillus actinomycetemcomitans. Clin Exp Immunol. 1982;47:43-52 pubmed
    The association between periodontal disease in humans and serum and salivary antibody to Actinobacillus actinomycetemcomitans strain Y4 was determined...
  22. Matter D, Rossano A, Limat S, Vorlet Fawer L, Brodard I, Perreten V. Antimicrobial resistance profile of Actinobacillus pleuropneumoniae and Actinobacillus porcitonsillarum. Vet Microbiol. 2007;122:146-56 pubmed
    A total of 83 Actinobacillus pleuropneumoniae and 58 Actinobacillus porcitonsillarum strains collected from slaughtered pigs in Switzerland were screened for susceptibility to 20 antimicrobial agents by MIC determinations...
  23. Jang Y, Jung Y, Lee S, Kim J, Lee J, Oh D, et al. Construction and characterization of shuttle vectors for succinic acid-producing rumen bacteria. Appl Environ Microbiol. 2007;73:5411-20 pubmed
    ..that function in Escherichia coli and two capnophilic rumen bacteria, Mannheimia succiniciproducens and Actinobacillus succinogenes, were constructed. These vectors were found to be present at ca. 10 copies per cell...
  24. Del Rio M, Martín C, Navas J, Gutiérrez Muñiz B, Rodriguez Barbosa J, Rodriguez Ferri E. aroA gene PCR-RFLP diversity patterns in Haemophilus parasuis and Actinobacillus species. Res Vet Sci. 2006;80:55-61 pubmed
    ..parasuis and Actinobacillus species. PCR amplification of the aroA gene rendered a 1,067-bp fragment in all 15 H...
  25. Lone A, Deslandes V, Nash J, Jacques M, MacInnes J. Modulation of gene expression in Actinobacillus pleuropneumoniae exposed to bronchoalveolar fluid. PLoS ONE. 2009;4:e6139 pubmed publisher
    b>Actinobacillus pleuropneumoniae, the causative agent of porcine contagious pleuropneumonia, is an important pathogen of swine throughout the world. It must rapidly overcome the innate pulmonary immune defenses of the pig to cause disease...
  26. Kuhnert P, Schlatter Y, Frey J. Characterization of the type I secretion system of the RTX toxin ApxII in "Actinobacillus porcitonsillarum". Vet Microbiol. 2005;107:225-32 pubmed
    Strains of Actinobacillus porcitonsillarum are regularly isolated from the tonsils of healthy pigs. A...
  27. McKinlay J, Shachar Hill Y, Zeikus J, Vieille C. Determining Actinobacillus succinogenes metabolic pathways and fluxes by NMR and GC-MS analyses of 13C-labeled metabolic product isotopomers. Metab Eng. 2007;9:177-92 pubmed
    b>Actinobacillus succinogenes is a promising candidate for industrial succinate production. However, in addition to producing succinate, it also produces formate and acetate...
  28. McKinlay J, Vieille C. 13C-metabolic flux analysis of Actinobacillus succinogenes fermentative metabolism at different NaHCO3 and H2 concentrations. Metab Eng. 2008;10:55-68 pubmed
    b>Actinobacillus succinogenes naturally produces high concentrations of succinate, a potential intermediary feedstock for bulk chemical productions. A...
  29. Zheng P, Dong J, Sun Z, Ni Y, Fang L. Fermentative production of succinic acid from straw hydrolysate by Actinobacillus succinogenes. Bioresour Technol. 2009;100:2425-9 pubmed publisher
    In this work, straw hydrolysates were used to produce succinic acid by Actinobacillus succinogenes CGMCC1593 for the first time...
  30. Park D, Laivenieks M, Guettler M, Jain M, Zeikus J. Microbial utilization of electrically reduced neutral red as the sole electron donor for growth and metabolite production. Appl Environ Microbiol. 1999;65:2912-7 pubmed
    ..5 V) generated from an electric current (0.3 to 1.0 mA), and it was subsequently oxidized by Actinobacillus succinogenes or by mixed methanogenic cultures. The A...
  31. Kim P, Laivenieks M, Vieille C, Zeikus J. Effect of overexpression of Actinobacillus succinogenes phosphoenolpyruvate carboxykinase on succinate production in Escherichia coli. Appl Environ Microbiol. 2004;70:1238-41 pubmed
    Succinate fermentation was investigated in Escherichia coli strains overexpressing Actinobacillus succinogenes phosphoenolpyruvate carboxykinase (PEPCK). In E. coli K-12, PEPCK overexpression had no effect on succinate fermentation...
  32. Christensen H, Bisgaard M, Bojesen A, Mutters R, Olsen J. Genetic relationships among avian isolates classified as Pasteurella haemolytica, 'Actinobacillus salpingitidis' or Pasteurella anatis with proposal of Gallibacterium anatis gen. nov., comb. nov. and description of additional genomospecies within Gal. Int J Syst Evol Microbiol. 2003;53:275-87 pubmed
    Bacteria of the avian [Pasteurella haemolytica]-'Actinobacillus salpingitidis' complex have been associated with different pathological conditions in birds, among which salpingitis and peritonitis in chickens of layer type seem to ..
  33. Lei J, Wu C, Wang X, Wang H. p38 MAPK-dependent and YY1-mediated chemokine receptors CCR5 and CXCR4 up-regulation in U937 cell line infected by Mycobacterium tuberculosis or Actinobacillus actinomycetemcomitans. Biochem Biophys Res Commun. 2005;329:610-5 pubmed
    ..the expression changes of these two chemokine receptors in macrophages attacked by another bacterium Actinobacillus actinomycetemcomitans (AA) (from mRNA level and protein level)...
  34. Arya G, Niven D. Production of haemolysins by strains of the Actinobacillus minor/"porcitonsillarum" complex. Vet Microbiol. 2010;141:332-41 pubmed publisher
    b>Actinobacillus minor and "Actinobacillus porcitonsillarum" are distinguished by their haemolytic activities, the latter organism being haemolytic and the former, non-haemolytic...
  35. Kim P, Laivenieks M, McKinlay J, Vieille C, Gregory Zeikus J. Construction of a shuttle vector for the overexpression of recombinant proteins in Actinobacillus succinogenes. Plasmid. 2004;51:108-15 pubmed
    To express foreign proteins in Actinobacillus succinogenes, a shuttle vector was constructed based on the Actinobacillus pleuropneumoniae-Escherichia coli shuttle vector, pGZRS-19. We demonstrated that A...
  36. Chen K, Li J, Ma J, Jiang M, Wei P, Liu Z, et al. Succinic acid production by Actinobacillus succinogenes using hydrolysates of spent yeast cells and corn fiber. Bioresour Technol. 2011;102:1704-8 pubmed publisher
    ..enzymatic hydrolysate of spent yeast cells was evaluated as a nitrogen source for succinic acid production by Actinobacillus succinogenes NJ113, using corn fiber hydrolysate as a carbon source...
  37. Foster G, Ross H, Patterson I, Hutson R, Collins M. Actinobacillus scotiae sp. nov., a new member of the family Pasteurellaceae Pohl (1979) 1981 isolated from porpoises (Phocoena phocoena). Int J Syst Bacteriol. 1998;48 Pt 3:929-33 pubmed
    ..The nearest phylogenetic relative of the unknown bacterium was Actinobacillus delphinicola, an organism also originating from sea mammals, although a sequence divergence of 3% demonstrated ..
  38. Chang Y, Young R, Struck D. Cloning and characterization of a hemolysin gene from Actinobacillus (Haemophilus) pleuropneumoniae. DNA. 1989;8:635-47 pubmed
    Neutralizing antisera to the leukotoxin secreted by Pasteurella haemolytica neutralized the hemolysin of Actinobacillus pleuropneumoniae and recognized a 110-kD antigen in cell-free culture supernatants from this organism...
  39. Du C, Lin S, Koutinas A, Wang R, Webb C. Succinic acid production from wheat using a biorefining strategy. Appl Microbiol Biotechnol. 2007;76:1263-70 pubmed
    ..In the second stage, the generic feedstock was converted into succinic acid by bacterial fermentation by Actinobacillus succinogenes...
  40. Nakano Y, Yoshida Y, Suzuki N, Yamashita Y, Koga T. A gene cluster for the synthesis of serotype d-specific polysaccharide antigen in Actinobacillus actinomycetemcomitans. Biochim Biophys Acta. 2000;1493:259-63 pubmed
    The serotype d antigen of Actinobacillus actinomycetemcomitans consists of D-glucose, D-mannose, and L-rhamnose in a molar ratio of 1:2:1...
  41. Dousse F, Thomann A, Brodard I, Korczak B, Schlatter Y, Kuhnert P, et al. Routine phenotypic identification of bacterial species of the family Pasteurellaceae isolated from animals. J Vet Diagn Invest. 2008;20:716-24 pubmed
    ..A new and simplified procedure to identify species of Actinobacillus, Avibacterium, Gallibacterium, Haemophilus, Mannheimia, Nicoletella, and Pasteurella, which are most commonly ..
  42. Tajima Y, Yamamoto Y, Fukui K, Nishio Y, Hashiguchi K, Usuda Y, et al. Impact of an energy-conserving strategy on succinate production under weak acidic and anaerobic conditions in Enterobacter aerogenes. Microb Cell Fact. 2015;14:80 pubmed publisher
    ..development of the ES08ΔptsG strain, which contains the following modifications: chromosomally expressed Actinobacillus succinogenes phosphoenolpyruvate carboxykinase, enhanced fumarate reductase, inactivated pyruvate formate ..
  43. Sassu E, Bosse J, Tobias T, Gottschalk M, Langford P, Hennig Pauka I. Update on Actinobacillus pleuropneumoniae-knowledge, gaps and challenges. Transbound Emerg Dis. 2017;: pubmed publisher
    Porcine pleuropneumonia, caused by the bacterial porcine respiratory tract pathogen Actinobacillus pleuropneumoniae, leads to high economic losses in affected swine herds in most countries of the world...
  44. Song Q, Wu Z, Fan Y, Song W, Zhang P, Wang L, et al. Production of homogeneous glycoprotein with multisite modifications by an engineered N-glycosyltransferase mutant. J Biol Chem. 2017;292:8856-8863 pubmed publisher
    ..In this study we found that ApNGT, a newly discovered cytoplasmic N-glycosyltransferase from Actinobacillus pleuropneumoniae, has strict selectivity toward the residues around the Asn of N-glycosylation ..
  45. Denadai A, Teixeira K, Santoro M, Pimenta A, Cortes M, Sinisterra R. Supramolecular self-assembly of beta-cyclodextrin: an effective carrier of the antimicrobial agent chlorhexidine. Carbohydr Res. 2007;342:2286-96 pubmed
    ..These were used to determine the initial and the long-term antimicrobial activity, respectively, toward Actinobacillus actinomycetemcomitans (A.a.) (Y4-FDC) and Enterococcus faecalis (E.f.) (ATCC 14508) strains...
  46. Jiang M, Xu R, Xi Y, Zhang J, Dai W, Wan Y, et al. Succinic acid production from cellobiose by Actinobacillus succinogenes. Bioresour Technol. 2013;135:469-74 pubmed publisher
    In this study, cellobiose, a reducing disaccharide was used to produce succinic acid by Actinobacillus succinogenes NJ113. A final succinic acid concentration of 30.3g/l with a yield of 67...
  47. Bowring B, Fahy V, Morris A, Collins A. An unusual culprit: Klebsiella pneumoniae causing septicaemia outbreaks in neonatal pigs?. Vet Microbiol. 2017;203:267-270 pubmed publisher
    ..coli and beta-haemolytic streptococci. Infrequent causes of septicaemia are Actinobacillus suis and Citrobacter freundii...
  48. Zhang J, Quan C, Wang C, Wu H, Li Z, Ye Q. Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production. Microb Cell Fact. 2016;15:38 pubmed publisher
    ..well as GSH degradation were systematically manipulated in Escherichia coli strains over-expressing gshF from Actinobacillus succinogenes...
  49. Zheng P, Zhang K, Yan Q, Xu Y, Sun Z. Enhanced succinic acid production by Actinobacillus succinogenes after genome shuffling. J Ind Microbiol Biotechnol. 2013;40:831-40 pubmed publisher
    ..The present work will be propitious to the development of a bio-succinic acid fermentation industry. ..
  50. Antenucci F, Fougeroux C, Bosse J, Magnowska Z, Roesch C, Langford P, et al. Identification and characterization of serovar-independent immunogens in Actinobacillus pleuropneumoniae. Vet Res. 2017;48:74 pubmed publisher
    Despite numerous actions to prevent disease, Actinobacillus pleuropneumoniae (A. pleuropneumoniae) remains a major cause of porcine pleuropneumonia, resulting in economic losses to the swine industry worldwide...
  51. Kroll J, Langford P, Wilks K, Keil A. Bacterial [Cu,Zn]-superoxide dismutase: phylogenetically distinct from the eukaryotic enzyme, and not so rare after all!. Microbiology. 1995;141 ( Pt 9):2271-9 pubmed publisher
    ..genes encoding [Cu,Zn]-SOD in a wide range of important human and animal pathogens-members of the Haemophilus, Actinobacillus and Pasteurella (HAP) group, and Neisseria meningitidis...
  52. Angen O, Ahrens P, Tegtmeier C. Development of a PCR test for identification of Haemophilus somnus in pure and mixed cultures. Vet Microbiol. 1998;63:39-48 pubmed
    ..somnus both in pure and mixed cultures. It represents a quick, sensitive and reliable method for identification of bacteria belonging to this phenotypically heterogeneous and often slow growing species...
  53. Wang L, Qin W, Zhang J, Bao C, Zhang H, Che Y, et al. Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38 which induces apoptosis of PAMs and IL-8 release. Sci Rep. 2016;6:24058 pubmed publisher
    ..Our previous studies demonstrated that Adh from Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is required for full bacterial pathogenicity...
  54. Yeruham I, Orgrad U, Perl S. Granulomatous lesion in the brain of a four-month-old female calf. Vet Rec. 2004;155:404 pubmed
  55. Park B, Han J, Shin D, Jeong Y, Lee N. Complete Genome Sequence of Actinobacillus pleuropneumoniae Strain KL 16 (Serotype 1). Genome Announc. 2017;5: pubmed publisher
    i>Actinobacillus pleuropneumoniae is a bacterial pathogen causing highly contagious porcine pleuropneumonia. Due to limited information on this species, it is difficult to study the biology of A...
  56. Hedegaard J, Okkels H, Bruun B, Kilian M, Mortensen K, Nørskov Lauritsen N. Phylogeny of the genus Haemophilus as determined by comparison of partial infB sequences. Microbiology. 2001;147:2599-609 pubmed
    ..aphrophilus/paraphrophilus and Actinobacillus actinomycetemcomitans were only remotely related to the type species of the genus Haemophilus H...
  57. Alexandri M, Papapostolou H, Komaitis M, Stragier L, Verstraete W, Danezis G, et al. Evaluation of an integrated biorefinery based on fractionation of spent sulphite liquor for the production of an antioxidant-rich extract, lignosulphonates and succinic acid. Bioresour Technol. 2016;214:504-513 pubmed publisher
    ..out using the pretreated SSL with isopropanol led to the production of around 19g/L of succinic acid by both Actinobacillus succinogenes and Basfia succiniciproducens...
  58. Pataro A, Franco C, Santos V, Cortés M, Sinisterra R. Surface effects and desorption of tetracycline supramolecular complex on bovine dentine. Biomaterials. 2003;24:1075-80 pubmed
    ..Each slab was tested in a broth of overnight culture of Actinobacillus actinomycetemcomitans (Y4-FDC). The inclusion complex significantly inhibited the A...
  59. Ferone M, Raganati F, Olivieri G, Salatino P, Marzocchella A. Biosuccinic Acid from Lignocellulosic-Based Hexoses and Pentoses by Actinobacillus succinogenes: Characterization of the Conversion Process. Appl Biochem Biotechnol. 2017;183:1465-1477 pubmed publisher
    Succinic acid (SA) is a well-established chemical building block. Actinobacillus succinogenes fermentation is by far the most investigated route due to very promising high SA yield and titer on several sugars...
  60. Blackall P, Bisgaard M, McKenzie R. Characterisation of Australian isolates of Actinobacillus capsulatus, Actinobacillus equuli, Pasteurella caballi and Bisgaard Taxa 9 and 11. Aust Vet J. 1997;75:52-5 pubmed
    The objective of this work was to perform a comprehensive phenotypic characterisation of 16 isolates of bacteria previously identified as Actinobacillus equuli.
  61. Zhou X, Zheng P. Spirit-based distillers' grain as a promising raw material for succinic acid production. Biotechnol Lett. 2013;35:679-84 pubmed publisher
    ..The economical potential of fermentative production of succinic acid from SDG was investigated using Actinobacillus succinogens. Use of pretreated SDG (PSDG) as the sole source of C and N yielded succinic acid at 35...
  62. Gmür R, Guggenheim B. Monoclonal antibodies for the detection of 'periodontopathic' bacteria. Arch Oral Biol. 1990;35 Suppl:145S-151S pubmed
    ..Bacteroides forsythus, Bact. gingivalis, Bact. intermedius and Wolinella recta, but not Actinobacillus actinomycetemcomitans were found in sites of adult periodontitis with high prevalence but quite distinct ..
  63. George S, Hamblin M, Kishen A. Uptake pathways of anionic and cationic photosensitizers into bacteria. Photochem Photobiol Sci. 2009;8:788-95 pubmed publisher
    ..PSs, rose bengal (RB) and indocyanine green (ICG), by Gram-positive Enterococcus faecalis and Gram-negative Actinobacillus actinomycetemcomitans was examined...
  64. Steelman R, Einzig S, Balian A, Thomas J, Rosen D, Gustafson R, et al. Increased susceptibility to gingival colonization by specific HACEK microbes in children with congenital heart disease. J Clin Pediatr Dent. 2000;25:91-4 pubmed
    It is well established that infective endocarditis (IE) involving the HACEK (Hemophilus, Actinobacillus, Cardiobacter, Eikenella, Kingella) group of microbes occurs in patients with congenital heart defects (CHD) and in those with ..
  65. Padmanabhan B, Paehler A, Horikoshi M. Structure of creatine amidinohydrolase from Actinobacillus. Acta Crystallogr D Biol Crystallogr. 2002;58:1322-8 pubmed
    The crystal structure of Actinobacillus creatine amidinohydrolase has been solved by molecular replacement. The amino-acid sequence has been derived from the crystal structure...
  66. Li Q, Lei J, Zhang R, Li J, Xing J, Gao F, et al. Efficient decolorization and deproteinization using uniform polymer microspheres in the succinic acid biorefinery from bio-waste cotton (Gossypium hirsutum L.) stalks. Bioresour Technol. 2013;135:604-9 pubmed publisher
    ..stalks were converted into succinic acid by simultaneous saccharification and fermentation (SSF) using Actinobacillus succinogenes 130Z. After 54 h SSF at 40 °C and pH 7.0, the production of succinic acid was 63 g/L, with 1...
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    b>Actinobacillus species are usually not considered as being human pathogens apart from A. actinomycetemcomitans...
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    ..This work investigates the production of succinic acid by immobilized A. succinogenes cells, using a bioreactor with stirred/mobile bed of biocatalysts...
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    ..Therefore, for the first time, cells have been engineered that are able to displace an existing biofilm and then be removed on command allowing one to control consortial biofilm formation for various applications...
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    Isolates of Actinobacillus seminis from clinical cases and reference sources had markedly similar Bam H1 restriction endonuclease profiles but were readily distinguishable from the Bam H1 profiles of the Histophilus-Haemophilus group as ..
  71. Lapointe L, D Allaire S, Lacouture S, Gottschalk M. Serologic profile of a cohort of pigs and antibody response to an autogenous vaccine for Actinobacillus suis. Vet Res. 2001;32:175-83 pubmed
    b>Actinobacillus suis is a commensal opportunistic pathogen in swine. However, in recent years, an increasing prevalence of clinical signs associated with A. suis has been observed in high health status herds in North America...
  72. Fodor L, Varga J, Molnar E, Hajtós I. Biochemical and serological properties of Actinobacillus pleuropneumoniae biotype 2 strains isolated from swine. Vet Microbiol. 1989;20:173-80 pubmed
    The biochemical and serological properties of 21 strains of Actinobacillus pleuropneumoniae biotype 2 isolated from haemorrhagic necrotic pleuropneumonia of swine were examined...
  73. Alexandri M, Papapostolou H, Stragier L, Verstraete W, Papanikolaou S, Koutinas A. Succinic acid production by immobilized cultures using spent sulphite liquor as fermentation medium. Bioresour Technol. 2017;238:214-222 pubmed publisher
    ..liquor (SSL) was used as carbon source for the production of succinic acid using immobilized cultures of Actinobacillus succinogenes and Basfia succiniciproducens on two different supports, delignified cellulosic material (DCM) ..
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    ..The most prevalent anaerobic rods prior to and 60 days after therapy were Fusobacterium nucleatum, Bacteroides gingivalis, and B. intermedius.(ABSTRACT TRUNCATED AT 250 WORDS)..
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    ..design (PBD), steepest ascent method (SA), and Box-Behnken design (BBD) was developed to optimize Actinobacillus succinogenes ATCC 55618 fermentation medium...
  78. Zambon J, Sunday G, Smutko J. Molecular genetic analysis of Actinobacillus actinomycetemcomitans epidemiology. J Periodontol. 1990;61:75-80 pubmed
    ..past decade has identified many of the microorganisms involved in the etiology of human periodontitis such as Actinobacillus actinomycetemcomitans. Efforts are now directed toward defining these species' role in the pathogenic process...