chlamydophila

Summary

Summary: A genus of the family CHLAMYDIACEAE comprising gram-negative non CHLAMYDIA TRACHOMATIS-like species infecting vertebrates. Chlamydophila do not produce detectable quantities of glycogen. The type species is CHLAMYDOPHILA PSITTACI.

Top Publications

  1. Greco G, Totaro M, Madio A, Tarsitano E, Fasanella A, Lucifora G, et al. Detection of Chlamydophila abortus in sheep and goat flocks in southern Italy by PCR using four different primer sets. Vet Res Commun. 2005;29 Suppl 1:107-15 pubmed
    An epidemiological survey was performed to detect the presence of Chlamydophila (C.) abortus and other members of the order Chlamydiales in ovine and caprine flocks with a history of abortion in southern Italy...
  2. Wheelhouse N, Aitchison K, Spalding L, Livingstone M, Longbottom D. Transcriptional analysis of in vitro expression patterns of Chlamydophila abortus polymorphic outer membrane proteins during the chlamydial developmental cycle. Vet Res. 2009;40:47 pubmed publisher
    b>Chlamydophila abortus is the aetiological agent of ovine enzootic abortion. Sequencing, annotation and comparative analysis of the genome of C...
  3. Loots K, Loock M, Vanrompay D, Goddeeris B. CpG motifs as adjuvant in DNA vaccination against Chlamydophila psittaci in turkeys. Vaccine. 2006;24:4598-601 pubmed
    Plasmid DNA (pcDNA1::MOMP) expressing the major outer membrane protein (MOMP) of an avian Chlamydophila psittaci serovar D strain and recombinant MOMP (rMOMP) with or without the immunomodulating CpG oligonucleotides (CpG ON) were tested ..
  4. Navarro J, García de la Fuente J, Sanchez J, Martinez C, Buendia A, Gutiérrez Martín C, et al. Kinetics of infection and effects on the placenta of Chlamydophila abortus in experimentally infected pregnant ewes. Vet Pathol. 2004;41:498-505 pubmed
    A Chlamydophila abortus-induced abortion model was carried out on the basis of the experimental infection of ewes at day 75 of gestation. The infection induced abortions and the birth of weak lambs during the last 3 weeks of pregnancy...
  5. Amin A. Application of touchdown enzyme time release (TETR)-PCR for diagnosis of Chlamydophila abortus infection. Res Vet Sci. 2003;74:213-7 pubmed
    b>Chlamydophila abortus-DNA was detected using a touchdown enzyme time-release (TETR)-polymerase chain reaction (PCR) assay as an improved test for sensitive and rapid diagnosis of abortion in small ruminants...
  6. Halanova M, Sulinova Z, Cislakova L, Trbolová A, Palenik L, Weissova T, et al. Chlamydophila felis in cats--are the stray cats dangerous source of infection?. Zoonoses Public Health. 2011;58:519-22 pubmed publisher
    b>Chlamydophila felis is a causative agent of acute or chronic conjunctivitis, and pneumonia in cats. Natural transmission mostly occurs consequently to close contact with other infected cats, their aerosol and fomites...
  7. Twomey D, Griffiths P, Hignett B, Martin T. Suspected chlamydial polyarthritis in a calf in the UK. Vet Rec. 2003;152:340 pubmed
  8. Cai Y, Fukushi H, Koyasu S, Kuroda E, Yamaguchi T, Hirai K. An etiological investigation of domestic cats with conjunctivitis and upper respiratory tract disease in Japan. J Vet Med Sci. 2002;64:215-9 pubmed
    b>Chlamydophila felis (C. felis), feline herpesvirus-1 (FHV-1) and feline calicivirus (FCV) were detected in 39 (59.1%), 11 (16.7%) and 14 (21...
  9. Longbottom D, Livingstone M. Vaccination against chlamydial infections of man and animals. Vet J. 2006;171:263-75 pubmed
    ..has been in developing whole organism based killed or live attenuated vaccines against the animal pathogens Chlamydophila abortus and Chlamydophila felis...

More Information

Publications87

  1. Wang F, Shieh H, Liao Y. Prevalence of Chlamydophila abortus infection in domesticated ruminants in Taiwan. J Vet Med Sci. 2001;63:1215-20 pubmed
    This study is to (1) investigate the prevalence of Chlamydophila abortus infection in cows and goats in Taiwan, and (2) compare the genetic properties of Taiwanese isolates with abortion strains from other sources...
  2. Rocchi M, Wattegedera S, Meridiani I, Entrican G. Protective adaptive immunity to Chlamydophila abortus infection and control of ovine enzootic abortion (OEA). Vet Microbiol. 2009;135:112-21 pubmed publisher
    ..The causative agent, Chlamydophila abortus, is a Gram-negative bacterium that can induce a persistent, subclinical infection in non-pregnant ..
  3. Wilson K, Livingstone M, Longbottom D. Comparative evaluation of eight serological assays for diagnosing Chlamydophila abortus infection in sheep. Vet Microbiol. 2009;135:38-45 pubmed publisher
    b>Chlamydophila abortus is one of the principal causes of late-term abortion (enzootic abortion of ewes or EAE) in sheep across Europe...
  4. Harley R, Day S, Di Rocco C, Helps C. The Chlamydophila felis plasmid is highly conserved. Vet Microbiol. 2010;146:172-4 pubmed publisher
    ..Although strains of Chlamydophila felis with or without the plasmid have been identified, only a small number of laboratory-adapted strains have ..
  5. Rampazzo A, Appino S, Pregel P, Tarducci A, Zini E, Biolatti B. Prevalence of Chlamydophila felis and feline herpesvirus 1 in cats with conjunctivitis in northern Italy. J Vet Intern Med. 2003;17:799-807 pubmed
    The prevalence of Chlamydophila felis and feline herpesvirus 1 (FHV-1) infection in cats with conjunctivitis in northern Italy was investigated by conventional polymerase chain reaction (PCR) testing...
  6. Everson J, Garner S, Fane B, Liu B, Lambden P, Clarke I. Biological properties and cell tropism of Chp2, a bacteriophage of the obligate intracellular bacterium Chlamydophila abortus. J Bacteriol. 2002;184:2748-54 pubmed
    ..Phylogenetic studies divide the Chlamydiaceae into two distinct genera, Chlamydia and Chlamydophila, containing three and six different species, respectively...
  7. Hoelzle K, Wittenbrink M, Corboz L, Hoelzle L. Chlamydophila abortus-induced keratoconjunctivitis in a dog. Vet Rec. 2005;157:632-3 pubmed
  8. Borel N, Sachse K, Rassbach A, Bruckner L, Vretou E, Psarrou E, et al. Ovine enzootic abortion (OEA): antibody response in vaccinated sheep compared to naturally infected sheep. Vet Res Commun. 2005;29 Suppl 1:151-6 pubmed
  9. Livingstone M, Entrican G, Wattegedera S, Buxton D, McKendrick I, Longbottom D. Antibody responses to recombinant protein fragments of the major outer membrane protein and polymorphic outer membrane protein POMP90 in Chlamydophila abortus-infected pregnant sheep. Clin Diagn Lab Immunol. 2005;12:770-7 pubmed
    b>Chlamydophila abortus is one of the major causes of infectious abortion in pregnant sheep (enzootic abortion of ewes or EAE) worldwide...
  10. Sachse K, Vretou E, Livingstone M, Borel N, Pospischil A, Longbottom D. Recent developments in the laboratory diagnosis of chlamydial infections. Vet Microbiol. 2009;135:2-21 pubmed publisher
    There are two main approaches to diagnosing infections by Chlamydia and Chlamydophila spp. in mammals and birds...
  11. Godin A, Björkman C, Englund S, Johansson K, Niskanen R, Alenius S. Investigation of Chlamydophila spp. in dairy cows with reproductive disorders. Acta Vet Scand. 2008;50:39 pubmed publisher
    Reports worldwide indicate high prevalence of Chlamydophila spp. infection in cattle. To assess the prevalence in Sweden, 525 cows in 70 dairy herds with reproductive disorders was investigated.
  12. Rodolakis A, Yousef Mohamad K. Zoonotic potential of Chlamydophila. Vet Microbiol. 2010;140:382-91 pubmed publisher
    ..The purpose of this article is to present the diseases induced in humans and animals by the different species of Chlamydophila, after providing an overview on the history of these infectious agents and their taxonomy...
  13. Sait M, Livingstone M, Graham R, Inglis N, Wheelhouse N, Longbottom D. Identification, sequencing and molecular analysis of Chp4, a novel chlamydiaphage of Chlamydophila abortus belonging to the family Microviridae. J Gen Virol. 2011;92:1733-7 pubmed publisher
    ..family Microviridae have been identified in a number of chlamydial species infecting humans (phage CPAR39 in Chlamydophila pneumoniae), other mammals (?CPG1 in Chlamydophila caviae, Chp2 in Chlamydophila abortus and Chp3 in ..
  14. Buendia A, Martinez C, Ortega N, Del Rio L, Caro M, Gallego M, et al. Natural killer (NK) cells play a critical role in the early innate immune response to Chlamydophila abortus infection in mice. J Comp Pathol. 2004;130:48-57 pubmed
    b>Chlamydophila abortus, the aetiological agent of ovine enzootic abortion, induces a strong inflammatory reaction that leads to the T helper cell (Th1) specific immune response necessary for the clearance of infection...
  15. Wirz M, Polkinghorne A, Dumrese C, Ziegler U, Greub G, Pospischil A, et al. Predator or prey? Chlamydophila abortus infections of a free-living amoebae, Acanthamoeba castellani 9GU. Microbes Infect. 2008;10:591-7 pubmed publisher
    ..PCR and microscopic analyses of Chlamydophila abortus infections of Acanthamoeba castellani revealed uptake of this chlamydial pathogen but, unlike the well-..
  16. Jaeger J, Liebler Tenorio E, Kirschvink N, Sachse K, Reinhold P. A clinically silent respiratory infection with Chlamydophila spp. in calves is associated with airway obstruction and pulmonary inflammation. Vet Res. 2007;38:711-28 pubmed
    ..Thirteen calves persistently infected with Chlamydophila (C.) abortus and/or C. pecorum (Chl+) were compared to 12 calves without chlamydial infections (Chl-)...
  17. Helps C, Reeves N, Egan K, Howard P, Harbour D. Detection of Chlamydophila felis and feline herpesvirus by multiplex real-time PCR analysis. J Clin Microbiol. 2003;41:2734-6 pubmed
    b>Chlamydophila felis and feline herpesvirus (FHV) are pathogens commonly associated with feline respiratory and ocular disease...
  18. Ling Y, Li S, Yang J, Yuan J, He C. Co-administration of the polysaccharide of Lycium barbarum with DNA vaccine of Chlamydophila abortus augments protection. Immunol Invest. 2011;40:1-13 pubmed publisher
    ..active component of LBP3a, combined with a DNA vaccine encoding the major outer membrane protein (MOMP) of Chlamydophila abortus, induced protection in mice against challenge. Sixty BALB/c mice were randomly assigned to 5 groups...
  19. Gerhardt N, Schulz B, Werckenthin C, Hartmann K. Pharmacokinetics of enrofloxacin and its efficacy in comparison with doxycycline in the treatment of Chlamydophila felis infection in cats with conjunctivitis. Vet Rec. 2006;159:591-4 pubmed
    ..Enrofloxacin concentrations above the minimum inhibitory concentration of Chlamydophila felis were found in the saliva and tears of the cats with and without signs of upper respiratory tract ..
  20. García de la Fuente J, Gutiérrez Martín C, Ortega N, Rodriguez Ferri E, Del Rio M, Gonzalez O, et al. Efficacy of different commercial and new inactivated vaccines against ovine enzootic abortion. Vet Microbiol. 2004;100:65-76 pubmed
    ..For the preparation of the experimental vaccines, Chlamydophila abortus AB7 strain was cultured in McCoy cells and adjuvated with QS-21 (QS) or Montanide ISA 773 (M7)...
  21. Helps C, Reeves N, Tasker S, Harbour D. Use of real-time quantitative PCR to detect Chlamydophila felis infection. J Clin Microbiol. 2001;39:2675-6 pubmed
    A real-time PCR assay was developed to detect and quantify Chlamydophila felis infection of cats...
  22. Szeredi L, Hotzel H, Sachse K. High prevalence of chlamydial (Chlamydophila psittaci) infection in fetal membranes of aborted equine fetuses. Vet Res Commun. 2005;29 Suppl 1:37-49 pubmed
    ..1%) from 41 (83.7%) different farms. Partial ompA gene sequencing of PCR products revealed that the agent was Chlamydophila psittaci...
  23. Mohamad K, Rodolakis A. Recent advances in the understanding of Chlamydophila pecorum infections, sixteen years after it was named as the fourth species of the Chlamydiaceae family. Vet Res. 2010;41:27 pubmed publisher
    b>Chlamydophila pecorum found in the intestine and vaginal mucus of asymptomatic ruminants has also been associated with different pathological conditions in ruminants, swine and koalas...
  24. Thomson N, Yeats C, Bell K, Holden M, Bentley S, Livingstone M, et al. The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation. Genome Res. 2005;15:629-40 pubmed
    The obligate intracellular bacterial pathogen Chlamydophila abortus strain S26/3 (formerly the abortion subtype of Chlamydia psittaci) is an important cause of late gestation abortions in ruminants and pigs...
  25. Borel N, Mukhopadhyay S, Kaiser C, Sullivan E, Miller R, Timms P, et al. Tissue MicroArray (TMA) analysis of normal and persistent Chlamydophila pneumoniae infection. BMC Infect Dis. 2006;6:152 pubmed
    b>Chlamydophila pneumoniae infection has been implicated as a potential risk factor for atherosclerosis, however the mechanism leading to persistent infection and its role in the disease process remains to be elucidated.
  26. Alzhanov D, Barnes J, Hruby D, Rockey D. Chlamydial development is blocked in host cells transfected with Chlamydophila caviae incA. BMC Microbiol. 2004;4:24 pubmed
    ..Little information exists regarding the interaction of Inc proteins with the eukaryotic cell. To examine these interactions, Vaccinia virus vectors and mammalian plasmid-based systems were used to express inc genes in mammalian cells...
  27. Entrican G, Wattegedera S, Rocchi M, Fleming D, Kelly R, Wathne G, et al. Induction of inflammatory host immune responses by organisms belonging to the genera Chlamydia/Chlamydophila. Vet Immunol Immunopathol. 2004;100:179-86 pubmed
    Chlamydia/Chlamydophila are a family of intracellular gram-negative bacteria that infect their hosts primarily via mucosal epithelia...
  28. Bouakane A, Benchaïeb I, Rodolakis A. Abortive potency of Chlamydophila abortus in pregnant mice is not directly correlated with placental and fetal colonization levels. Infect Immun. 2003;71:7219-22 pubmed
    Abortion, placental and fetal colonization, and levels of gamma interferon were analyzed for four Chlamydophila abortus strains presenting antigenic variations in a mouse model...
  29. Czopowicz M, Kaba J, Szalus Jordanow O, Nowicki M, Witkowski L, Nowicka D, et al. Prevalence of antibodies against Chlamydophila abortus and Coxiella burnetii in goat herds in Poland. Pol J Vet Sci. 2010;13:175-9 pubmed
    An epidemiological study was carried out to determine the herd prevalence of Chlamydophila abortus and Coxiella burnetii antibodies in goats covered by a milk recording program in Poland...
  30. Sammin D, Markey B, Quinn P, McElroy M, Bassett H. Comparison of fetal and maternal inflammatory responses in the ovine placenta after experimental infection with Chlamydophila abortus. J Comp Pathol. 2006;135:83-92 pubmed publisher
    Placentae from 13 pregnant ewes infected intravenously with Chlamydophila abortus, together with placentae from nine uninfected control ewes, were examined at 14, 21 or 28 days post-inoculation (p.i.)...
  31. Pantchev A, Sting R, Bauerfeind R, Tyczka J, Sachse K. Detection of all Chlamydophila and Chlamydia spp. of veterinary interest using species-specific real-time PCR assays. Comp Immunol Microbiol Infect Dis. 2010;33:473-84 pubmed publisher
    ..b>Chlamydophila (Cp.) abortus was the agent most frequently found in cattle, sheep, horses, goats, and pigs...
  32. Griffiths E, Ventresca M, Gupta R. BLAST screening of chlamydial genomes to identify signature proteins that are unique for the Chlamydiales, Chlamydiaceae, Chlamydophila and Chlamydia groups of species. BMC Genomics. 2006;7:14 pubmed
    ..The obligate intracellular nature of chlamydiae has also limited their genetic and biochemical studies. Thus, it is of importance to develop additional means for their identification and characterization...
  33. Vretou E, Katsiki E, Psarrou E, Vougas K, Tsangaris G. Identification and characterization of Inc766, an inclusion membrane protein in Chlamydophila abortus-infected cells. Microb Pathog. 2008;45:265-72 pubmed publisher
    We have identified the gene product of locus 766 in the transmembrane head region (TMH/Inc-region) in the Chlamydophila abortus genome by using mass spectrometry and a monoclonal antibody that reacted with the inclusion membrane...
  34. Buendía A, Fallon P, Del Rio L, Ortega N, Caro M, Gallego M, et al. Previous infection with the nematode Nippostrongylus brasiliensis alters the immune specific response against Chlamydophila abortus infection. Microb Pathog. 2002;33:7-15 pubmed
    ..interaction between the immune responses elicited following infection with Nippostrongylus brasiliensis and Chlamydophila abortus has been established. Mice infected with C. abortus 7 days after N...
  35. Kaleta E, Taday E. Avian host range of Chlamydophila spp. based on isolation, antigen detection and serology. Avian Pathol. 2003;32:435-61 pubmed
    Published reports and our own diagnostic data on the avian host range of avian Chlamydophila spp. are presented in an attempt to provide evidence for the large number of bird species that have been naturally infected with chlamydia...
  36. Sait M, Clark E, Wheelhouse N, Livingstone M, Spalding L, Siarkou V, et al. Genome sequence of the Chlamydophila abortus variant strain LLG. J Bacteriol. 2011;193:4276-7 pubmed publisher
    b>Chlamydophila abortus is a common cause of ruminant abortion. Here we report the genome sequence of strain LLG, which differs genotypically and phenotypically from the wild-type strain S26/3...
  37. Rocha E, Pradillon O, Bui H, Sayada C, Denamur E. A new family of highly variable proteins in the Chlamydophila pneumoniae genome. Nucleic Acids Res. 2002;30:4351-60 pubmed
    ..We find a larger potential for recombination in Chlamydophila pneumoniae genomes as compared with Chlamydia trachomatis or Chlamydia muridarum...
  38. Berri M, Rekiki A, Boumedine K, Rodolakis A. Simultaneous differential detection of Chlamydophila abortus, Chlamydophila pecorum and Coxiella burnetii from aborted ruminant's clinical samples using multiplex PCR. BMC Microbiol. 2009;9:130 pubmed publisher
    ..They are caused respectively by strictly intracellular and Gram negative bacterium Chlamydophila abortus (Cp. abortus) and Coxiella burnetii (C. burnetii). Chlamydophila pecorum (Cp...
  39. Fellerhoff B, Wank R. Increased prevalence of Chlamydophila DNA in post-mortem brain frontal cortex from patients with schizophrenia. Schizophr Res. 2011;129:191-5 pubmed publisher
    Infection can initiate symptoms of mental illness. It has been shown previously that Chlamydophila DNA is present six times more often in the blood of patients with schizophrenia than in the blood of control individuals...
  40. Vretou E, Radouani F, Psarrou E, Kritikos I, Xylouri E, Mangana O. Evaluation of two commercial assays for the detection of Chlamydophila abortus antibodies. Vet Microbiol. 2007;123:153-61 pubmed
    Two commercial enzyme-linked immunosorbent assays (ELISA), the CHEKIT-CHLAMYDIA which uses inactivated Chlamydophila psittaci antigen, and the Chlamydophila abortus ELISA produced by the Institut Pourquier which uses a recombinant ..
  41. Jee J, DeGraves F, Kim T, Kaltenboeck B. High prevalence of natural Chlamydophila species infection in calves. J Clin Microbiol. 2004;42:5664-72 pubmed
    We investigated the acquisition and prevalence of Chlamydophila sp. infection in calves. Specimens were collected at weekly intervals from birth to week 12 postpartum from 40 female Holstein calf-dam pairs in a dairy herd...
  42. Chu H, Weeks S, Gilligan D, Rockey D. Host alpha-adducin is redistributed and localized to the inclusion membrane in chlamydia- and chlamydophila-infected cells. Microbiology. 2008;154:3848-55 pubmed publisher
    ..trachomatis- and Chlamydophila caviae-infected cells, but the total cellular protein abundance remained unaffected by infection...
  43. Sachse K, Hotzel H, Slickers P, Ellinger T, Ehricht R. DNA microarray-based detection and identification of Chlamydia and Chlamydophila spp. Mol Cell Probes. 2005;19:41-50 pubmed
    ..The present assay proved suitable for unambiguous species identification of chlamydial cell cultures and showed a potential for direct detection of these bacteria from clinical tissue...
  44. Laroucau K, Vorimore F, Sachse K, Vretou E, Siarkou V, Willems H, et al. Differential identification of Chlamydophila abortus live vaccine strain 1B and C. abortus field isolates by PCR-RFLP. Vaccine. 2010;28:5653-6 pubmed publisher
    Comparative genomic analysis of a wild-type strain of the ovine pathogen Chlamydophila abortus and its nitrosoguanidine-induced, temperature-sensitive and virulence-attenuated live vaccine derivative identified point mutations unique to ..
  45. Siarkou V, Lambropoulos A, Chrisafi S, Kotsis A, Papadopoulos O. Subspecies variation in Greek strains of Chlamydophila abortus. Vet Microbiol. 2002;85:145-57 pubmed
    ..Using the restriction enzymes BfaI, SfcI, HpaI, BclI, DdeI and AclI, the strains were classified as Chlamydophila abortus...
  46. Biesenkamp Uhe C, Li Y, Hehnen H, Sachse K, Kaltenboeck B. Therapeutic Chlamydophila abortus and C. pecorum vaccination transiently reduces bovine mastitis associated with Chlamydophila infection. Infect Immun. 2007;75:870-7 pubmed
    Infections with Chlamydophila abortus and C. pecorum are highly prevalent in cattle and have been associated with bovine mastitis...
  47. Maley S, Livingstone M, Rodger S, Longbottom D, Buxton D. Identification of Chlamydophila abortus and the development of lesions in placental tissues of experimentally infected sheep. Vet Microbiol. 2009;135:122-7 pubmed publisher
    b>Chlamydophila (C.) abortus is a major cause of infectious abortion in sheep in many countries. Twenty-one pregnant sheep were experimentally infected intranasally with C. abortus at 70 days of gestation (dg)...
  48. Mohamad K, Rekiki A, Berri M, Rodolakis A. Recombinant 35-kDa inclusion membrane protein IncA as a candidate antigen for serodiagnosis of Chlamydophila pecorum. Vet Microbiol. 2010;143:424-8 pubmed publisher
    b>Chlamydophila pecorum strains are commonly found in the intestine and vaginal mucus of asymptomatic ruminants and may therefore induce a positive serological response when the animals are tested for C. abortus...
  49. Greco G, Corrente M, Buonavoglia D, Campanile G, Di Palo R, Martella V, et al. Epizootic abortion related to infections by Chlamydophila abortus and Chlamydophila pecorum in water buffalo (Bubalus bubalis). Theriogenology. 2008;69:1061-9 pubmed publisher
    ..By a nested-PCR assay, three of 14 vaginal swabs from aborted animals tested positive for Chlamydophila agents and, additionally, three out of seven aborted fetuses tested positive for Chlamydophila spp...
  50. Knitz J, Hoelzle L, Affolter P, Hamburger A, Zimmermann K, Heinritzi K, et al. [Humoral immune response in breeding sows after vaccination with a herd-specific Chlamydophila abortus vaccine]. Dtsch Tierarztl Wochenschr. 2003;110:369-74 pubmed
    ..in sterile 0.15 M saline was prepared from Chlamydophila (Ch.) abortus strain OCHL03/99 which has been isolated in the herd from a sample of vaginal discharge...
  51. Yousef Mohamad K, Rekiki A, Myers G, Bavoil P, Rodolakis A. Identification and characterisation of coding tandem repeat variants in incA gene of Chlamydophila pecorum. Vet Res. 2008;39:56 pubmed publisher
    Bacteria of the family Chlamydiaceae are obligate intracellular pathogens of human and animals. Chlamydophila pecorum is associated with different pathological conditions in ruminants, swine and koala...
  52. Amin A. Comparison of polymerase chain reaction and cell culture for the detection of Chlamydophila species in the semen of bulls, buffalo-bulls, and rams. Vet J. 2003;166:86-92 pubmed
    ..collected from 120 bulls, 60 buffalo-bulls, and 56 rams located on farms of known history of infection with Chlamydophila species...
  53. Livingstone M, Wheelhouse N, Maley S, Longbottom D. Molecular detection of Chlamydophila abortus in post-abortion sheep at oestrus and subsequent lambing. Vet Microbiol. 2009;135:134-41 pubmed publisher
    Enzootic abortion of ewes (EAE), resulting from infection with the bacterium Chlamydophila abortus (C. abortus), is a major cause of lamb loss in Europe...
  54. Helps C, Lait P, Damhuis A, Björnehammar U, Bolta D, Brovida C, et al. Factors associated with upper respiratory tract disease caused by feline herpesvirus, feline calicivirus, Chlamydophila felis and Bordetella bronchiseptica in cats: experience from 218 European catteries. Vet Rec. 2005;156:669-73 pubmed
    ..The prevalences of feline herpesvirus (FHV), feline calicivirus (FCV), Chlamydophila felis and Bordetella bronchiseptica were determined by PCR on swab samples...
  55. Ohya K, Takahara Y, Kuroda E, Koyasu S, Hagiwara S, Sakamoto M, et al. Chlamydophila felis CF0218 is a novel TMH family protein with potential as a diagnostic antigen for diagnosis of C. felis infection. Clin Vaccine Immunol. 2008;15:1606-15 pubmed publisher
    b>Chlamydophila felis is a causative agent of acute and chronic conjunctivitis and pneumonia in cats (feline chlamydiosis). Also, C...
  56. McCauley L, Lancaster M, Young P, Butler K, Ainsworth C. Comparison of ELISA and CFT assays for Chlamydophila abortus antibodies in ovine sera. Aust Vet J. 2007;85:325-8 pubmed
    To compare the sensitivity and specificity of Chlamydophila abortus antibody assays, to find a suitable serological assay for testing sheep for export.
  57. Padilla L, Huyvaert K, Merkel J, Miller R, Parker P. Hematology, plasma chemistry, serology, and Chlamydophila status of the waved albatross (Phoebastria irrorata) on the Galapagos Islands. J Zoo Wildl Med. 2003;34:278-83 pubmed
    ..Of 44 birds, 29 (66%) seroreacted to adenovirus group 1, and four seroreacted to avian encephalomyelitis. Cloacal swabs were negative for Chlamydophila psittaci DNA.
  58. Gutierrez J, Williams E, O Donovan J, Brady C, Proctor A, Marques P, et al. Monitoring clinical outcomes, pathological changes and shedding of Chlamydophila abortus following experimental challenge of periparturient ewes utilizing the natural route of infection. Vet Microbiol. 2011;147:119-26 pubmed publisher
    Enzootic abortion of ewes (EAE) caused by Chlamydophila abortus is an important disease resulting in significant lamb loss in most sheep producing countries. Ewes are considered to be naturally infected with C...
  59. Horn M, Collingro A, Schmitz Esser S, Beier C, Purkhold U, Fartmann B, et al. Illuminating the evolutionary history of chlamydiae. Science. 2004;304:728-30 pubmed
    ..Ancient chlamydiae appear to be the originators of mechanisms for the exploitation of eukaryotic cells...
  60. Twomey D, Griffiths P, Horigan M, Hignett B, Martin T. An investigation into the role of Chlamydophila spp. in bovine upper respiratory tract disease. Vet J. 2006;171:574-6 pubmed
    ..Conjunctival swabs were collected and tested for Chlamydophila spp. DNA using a PCR test that detects Chlamydophila abortus and Chlamydophila psittaci...
  61. Wheelhouse N, Aitchison K, Laroucau K, Thomson J, Longbottom D. Evidence of Chlamydophila abortus vaccine strain 1B as a possible cause of ovine enzootic abortion. Vaccine. 2010;28:5657-63 pubmed publisher
    b>Chlamydophila abortus, the agent of ovine enzootic abortion (OEA), is a major cause of lamb mortality worldwide. Disease can be controlled through the use of vaccines based on the 1B temperature-sensitive mutant strain of C. abortus...
  62. Holst B, Englund L, Palacios S, Renström L, Berndtsson L. Prevalence of antibodies against feline coronavirus and Chlamydophila felis in Swedish cats. J Feline Med Surg. 2006;8:207-11 pubmed
    ..from 214 Swedish cats with no signs of infectious disease were analysed for the presence of antibodies against Chlamydophila felis (Cp felis), while 209 of these were also analysed for feline coronavirus (FCoV) antibodies...
  63. Skilton R, Cutcliffe L, Pickett M, Lambden P, Fane B, Clarke I. Intracellular parasitism of chlamydiae: specific infectivity of chlamydiaphage Chp2 in Chlamydophila abortus. J Bacteriol. 2007;189:4957-9 pubmed
    ..An assay for phage infectivity is described, and the infectious properties of phage Chp2 were determined...
  64. Van Loock M, Vanrompay D, Herrmann B, Vander Stappen J, Volckaert G, Goddeeris B, et al. Missing links in the divergence of Chlamydophila abortus from Chlamydophila psittaci. Int J Syst Evol Microbiol. 2003;53:761-70 pubmed
    Pathological and serological evidence and DNA-DNA reassociation data indicate that Chlamydophila psittaci and Chlamydophila abortus are separate species. C. psittaci causes avian systemic disease and C. abortus causes abortion...
  65. Buendia A, Cuello F, Del Rio L, Gallego M, Caro M, Salinas J. Field evaluation of a new commercially available ELISA based on a recombinant antigen for diagnosing Chlamydophila abortus (Chlamydia psittaci serotype 1) infection. Vet Microbiol. 2001;78:229-39 pubmed
    A new commercially available ELISA (ELISAr-Chlamydia) for detecting antibodies against Chlamydophila abortus has been evaluated using sheep field serum samples...
  66. Bouakane A, Rekiki A, Rodolakis A. Protection of pregnant mice against placental and splenic infection by three strains of Chlamydophila abortus with a live 1B vaccine. Vet Rec. 2005;157:771-4 pubmed
    The efficacy of a live 1B vaccine against three strains of Chlamydophila abortus, AB16, LLG and POS, was assessed in pregnant mice in terms of the reduction in the levels of infection recorded in their placentas, fetuses and spleens...
  67. Meijer A, Brandenburg A, De Vries J, Beentjes J, Roholl P, Dercksen D. Chlamydophila abortus infection in a pregnant woman associated with indirect contact with infected goats. Eur J Clin Microbiol Infect Dis. 2004;23:487-90 pubmed
    Reported here is the case of a pregnant woman who developed a severe Chlamydophila abortus infection after indirect contact with infected goats resulting in preterm stillbirth. The woman fully recovered after treatment with doxycycline...
  68. Rekiki A, Bouakane A, Hammami S, El Idrissi A, Bernard F, Rodolakis A. Efficacy of live Chlamydophila abortus vaccine 1B in protecting mice placentas and foetuses against strains of Chlamydophila pecorum isolated from cases of abortion. Vet Microbiol. 2004;99:295-9 pubmed
    The efficacy of Chlamydophila abortus vaccine strain 1B in protecting against two selected Chlamydophila pecorum strains, isolated from an aborted goat (M14) in Morocco and a ewe (AB10) in France, was investigated in a mouse model, by ..
  69. Garner S, Everson J, Lambden P, Fane B, Clarke I. Isolation, molecular characterisation and genome sequence of a bacteriophage (Chp3) from Chlamydophila pecorum. Virus Genes. 2004;28:207-14 pubmed
    ..Comparative analyses demonstrate that the chlamydiaphages can be further subdivided into two groupings, one represented by Chp2/Chp3 and the other by ØCPG1/ØCPAR39...
  70. Hoelzle L, Hoelzle K, Wittenbrink M. Expression of the major outer membrane protein (MOMP) of Chlamydophila abortus, Chlamydophila pecorum, and Chlamydia suis in Escherichia coli using an arabinose-inducible plasmid vector. J Vet Med B Infect Dis Vet Public Health. 2003;50:383-9 pubmed
    The ompA genes encoding the 40 kDa major outer membrane protein (MOMP) of Chlamydophila (Ch.) abortus, Ch. pecorum, and Chlamydia (C...
  71. Laroucau K, Souriau A, Rodolakis A. Improved sensitivity of PCR for Chlamydophila using pmp genes. Vet Microbiol. 2001;82:155-64 pubmed
    Primers targeting the conserved pmp gene family of Chlamydophila abortus were evaluated for their ability to improve the polymerase chain reaction (PCR) sensitivity...
  72. Wheelhouse N, Wattegedera S, Stanton J, Maley S, Watson D, Jepson C, et al. Ovine trophoblast is a primary source of TNFalpha during Chlamydophila abortus infection. J Reprod Immunol. 2009;80:49-56 pubmed publisher
    b>Chlamydophila abortus is a Gram-negative obligate intracellular bacterium that causes infectious abortion in sheep (ovine enzootic abortion, OEA) and humans...
  73. Everson J, Garner S, Lambden P, Fane B, Clarke I. Host range of chlamydiaphages phiCPAR39 and Chp3. J Bacteriol. 2003;185:6490-2 pubmed
    The host range of phiCPAR39 is limited to four Chlamydophila species: C. abortus, C. caviae, C. pecorum, and C. pneumoniae. Chp3 (a newly discovered bacteriophage isolated from C. pecorum) shares three of these hosts (C. abortus, C...
  74. Perpinan D, Garner M, Wellehan J, Armstrong D. Mixed infection with reovirus and Chlamydophila in a flock of budgerigars (Melopsittacus undulatus). J Avian Med Surg. 2010;24:316-21 pubmed
    ..Polymerase chain reaction assays performed on liver and spleen samples were positive for Chlamydophila psittaci in 2 of 3 birds tested, and histologic findings in 2 additional birds were compatible with ..
  75. Borde G, Lowhar G, Adesiyun A. Toxoplasma gondii and Chlamydophila abortus in caprine abortions in Tobago: a sero-epidemiological study. J Vet Med B Infect Dis Vet Public Health. 2006;53:188-93 pubmed
    ..The sera were screened for Toxoplasma gondii antibodies using the latex agglutination test (LAT), Chlamydophila abortus with an enzyme-linked immunosorbent assay (ELISA) and Brucella abortus using the buffered plate ..
  76. Kaltenboeck B, Heinen E, Schneider R, Wittenbrink M, Schmeer N. OmpA and antigenic diversity of bovine Chlamydophila pecorum strains. Vet Microbiol. 2009;135:175-80 pubmed publisher
    Infections with the intracellular bacterium Chlamydophila (C.) pecorum are highly prevalent worldwide in cattle...
  77. Marques P, Souda P, O Donovan J, Gutierrez J, Gutierrez E, Worrall S, et al. Identification of immunologically relevant proteins of Chlamydophila abortus using sera from experimentally infected pregnant ewes. Clin Vaccine Immunol. 2010;17:1274-81 pubmed publisher
    b>Chlamydophila abortus is an intracellular pathogen and the etiological agent of enzootic abortion of ewes (EAE). C...
  78. Vretou E, Giannikopoulou P, Longbottom D, Psarrou E. Antigenic organization of the N-terminal part of the polymorphic outer membrane proteins 90, 91A, and 91B of Chlamydophila abortus. Infect Immun. 2003;71:3240-50 pubmed
    ..antigens, 61 to 74 residues in length, representing polymorphic outer membrane protein 90 (POMP90) of Chlamydophila abortus and two recombinant peptides spanning gene fragment p91Bf99 of POMP91B were assessed by immunoblotting ..