propionibacterium

Summary

Summary: A genus of gram-positive, rod-shaped bacteria whose cells occur singly, in pairs or short chains, in V or Y configurations, or in clumps resembling letters of the Chinese alphabet. Its organisms are found in cheese and dairy products as well as on human skin and can occasionally cause soft tissue infections.

Top Publications

  1. Sattler I, Roessner C, Stolowich N, Hardin S, Harris Haller L, Yokubaitis N, et al. Cloning, sequencing, and expression of the uroporphyrinogen III methyltransferase cobA gene of Propionibacterium freudenreichii (shermanii). J Bacteriol. 1995;177:1564-9 pubmed
    We cloned, sequenced, and overexpressed cobA, the gene encoding uroporphyrinogen III methyltransferase in Propionibacterium freudenreichii, and examined the catalytic properties of the enzyme...
  2. Kirjavainen P, ElNezami H, Salminen S, Ahokas J, Wright P. Effects of orally administered viable Lactobacillus rhamnosus GG and Propionibacterium freudenreichii subsp. shermanii JS on mouse lymphocyte proliferation. Clin Diagn Lab Immunol. 1999;6:799-802 pubmed
    ..In this study we examined the effects of Lactobacillus rhamnosus GG (LGG) and Propionibacterium freudenreichii subsp. shermanii JS (PJS) on the proliferative activity of murine lymphocytes ex vivo...
  3. Filya I, Sucu E, Karabulut A. The effects of Propionibacterium acidipropionici and Lactobacillus plantarum, applied at ensiling, on the fermentation and aerobic stability of low dry matter corn and sorghum silages. J Ind Microbiol Biotechnol. 2006;33:353-8 pubmed
    The aim of this work was to study the effects of applying a strain of Propionibacterium acidipropionici, with or without Lactobacillus plantarum, on the fermentation and aerobic stability characteristics of low dry matter (DM) corn (Zea ..
  4. Stein D, Allen D, Perry E, Bruner J, Gates K, Rehberger T, et al. Effects of feeding propionibacteria to dairy cows on milk yield, milk components, and reproduction. J Dairy Sci. 2006;89:111-25 pubmed
    ..total mixed rations (TMR), the low-dose group (n = 14) received the control TMR plus 6 x 10(10) cfu/cow of Propionibacterium strain P169 (P169), and the high-dose group (n = 11) received the control TMR plus 6 x 10(11) cfu/cow of ..
  5. Guan N, Liu L, Shin H, Chen R, Zhang J, Li J, et al. Systems-level understanding of how Propionibacterium acidipropionici respond to propionic acid stress at the microenvironment levels: mechanism and application. J Biotechnol. 2013;167:56-63 pubmed publisher
    In previous work, three evolved Propionibacterium acidipropionici mutants with higher tolerant capacity of propionic acid (PA) were obtained by genome shuffling. Here, we attempted to unravel the acid-tolerant mechanism of P...
  6. Park J, Lee J, Jung E, Park Y, Kim K, Park B, et al. In vitro antibacterial and anti-inflammatory effects of honokiol and magnolol against Propionibacterium sp. Eur J Pharmacol. 2004;496:189-95 pubmed
    ..However, until now, their antibacterial activity against Propionibacterium sp. has not been reported...
  7. Thierry A, Maillard M, Bonnarme P, Roussel E. The addition of Propionibacterium freudenreichii to Raclette cheese induces biochemical changes and enhances flavor development. J Agric Food Chem. 2005;53:4157-65 pubmed
    Two mixtures of Propionibacterium freudenreichii commercial strains were tested as adjunct cultures in pasteurized milk Raclette cheese to investigate the ability of propionibacteria (PAB) to enhance flavor development...
  8. Oksaharju A, Kooistra T, Kleemann R, van Duyvenvoorde W, Miettinen M, Lappalainen J, et al. Effects of probiotic Lactobacillus rhamnosus GG and Propionibacterium freudenreichii ssp. shermanii JS supplementation on intestinal and systemic markers of inflammation in ApoE*3Leiden mice consuming a high-fat diet. Br J Nutr. 2013;110:77-85 pubmed publisher
    ..In the present study, we explored the effects of two probiotic bacteria, Lactobacillus rhamnosus GG (GG) and Propionibacterium freudenreichii spp...
  9. Meile L, Le Blay G, Thierry A. Safety assessment of dairy microorganisms: Propionibacterium and Bifidobacterium. Int J Food Microbiol. 2008;126:316-20 pubmed
    The genera Propionibacterium and Bifidobacterium are clustered in the class Actinobacteria and form the anaerobic branch of coryneform bacteria. The dairy propionibacteria comprising four species P. freudenreichii, P. acidipropionici, P...

More Information

Publications98

  1. Deutsch S, Parayre S, Bouchoux A, Guyomarc h F, Dewulf J, Dols Lafargue M, et al. Contribution of surface ?-glucan polysaccharide to physicochemical and immunomodulatory properties of Propionibacterium freudenreichii. Appl Environ Microbiol. 2012;78:1765-75 pubmed publisher
    b>Propionibacterium freudenreichii is a bacterial species found in Swiss-type cheeses and is also considered for its health properties. The main claimed effect is the bifidogenic property...
  2. Liu Y, Zhang Y, Zhang R, Zhang F, Zhu J. Glycerol/glucose co-fermentation: one more proficient process to produce propionic acid by Propionibacterium acidipropionici. Curr Microbiol. 2011;62:152-8 pubmed publisher
    ..The effects of glycerol, glucose, and their mixtures on the propionic acid production by Propionibacterium acidipropionici CGMCC1...
  3. Kusano K, Yamada H, Niwa M, Yamasato K. Propionibacterium cyclohexanicum sp. nov., a new acid-tolerant omega-cyclohexyl fatty acid-containing propionibacterium isolated from spoiled orange juice. Int J Syst Bacteriol. 1997;47:825-31 pubmed
    ..level of homology is its level of homology with the representative of the classical propionibacteria, Propionibacterium freudenreichii (97.1%). Strain TA-12T is phenotypically similar to P...
  4. Dherbecourt J, Maillard M, Catheline D, Thierry A. Production of branched-chain aroma compounds by Propionibacterium freudenreichii: links with the biosynthesis of membrane fatty acids. J Appl Microbiol. 2008;105:977-85 pubmed publisher
    ..In Swiss cheese, the production of short BCFAs is mainly performed by Propionibacterium freudenreichii and is strain dependent...
  5. Kekkonen R, Lummela N, Karjalainen H, Latvala S, Tynkkynen S, Jarvenpaa S, et al. Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults. World J Gastroenterol. 2008;14:2029-36 pubmed
    ..lactis Bb12 (Bb12), or Propionibacterium freudenreichii ssp. shermanii JS (PJS) or a placebo drink for 3 wk...
  6. Schwenninger S, Meile L. A mixed culture of Propionibacterium jensenii and Lactobacillus paracasei subsp. paracasei inhibits food spoilage yeasts. Syst Appl Microbiol. 2004;27:229-37 pubmed
    ..tests with several antifungal lactobacilli led to the development of three protective cultures containing Propionibacterium jensenii SM11 and Lactobacillus paracasei subsp. paracasei strain SM20, SM29 or SM63...
  7. White S, Broadbent J, Oberg C, McMahon D. Effect of Lactobacillus helveticus and Propionibacterium freudenrichii ssp. shermanii combinations on propensity for split defect in Swiss cheese. J Dairy Sci. 2003;86:719-27 pubmed
    ..A 2 x 2 x 2 factorial experiment was used to determine the effect of different Lactobacillus helveticus/Propionibacterium freudenreichii ssp. shermanii starter culture combinations on the occurrence of split defect in Swiss cheese...
  8. Vanberg C, Lutnaes B, Langsrud T, Nes I, Holo H. Propionibacterium jensenii produces the polyene pigment granadaene and has hemolytic properties similar to those of Streptococcus agalactiae. Appl Environ Microbiol. 2007;73:5501-6 pubmed
    The red polyene pigment granadaene was purified and identified from Propionibacterium jensenii...
  9. Vasconcelos J, Elam N, Brashears M, Galyean M. Effects of increasing dose of live cultures of Lactobacillus acidophilus (Strain NP 51) combined with a single dose of Propionibacterium freudenreichii (Strain NP 24) on performance and carcass characteristics of finishing beef steers. J Anim Sci. 2008;86:756-62 pubmed
    ..design, were conducted to evaluate the effects of feeding live cultures of Lactobacillus acidophilus plus Propionibacterium freudenreichii on performance and carcass characteristics of feedlot cattle...
  10. Chen F, Feng X, Xu H, Zhang D, Ouyang P. Propionic acid production in a plant fibrous-bed bioreactor with immobilized Propionibacterium freudenreichii CCTCC M207015. J Biotechnol. 2012;164:202-10 pubmed publisher
    ..Starting at a concentration of 80g/L of glucose, Propionibacterium freudenreichii CCTCC M207015 produced 41.20±2.03g/L of propionic acid at 108h in the PFB. The value was 21...
  11. Peng M, Smith A, Rehberger T. Quantification of Propionibacterium acidipropionici P169 bacteria in environmental samples by use of strain-specific primers derived by suppressive subtractive hybridization. Appl Environ Microbiol. 2011;77:3898-902 pubmed publisher
    ..assay targeting a gene identified by suppressive subtractive hybridization (SSH) was developed to detect Propionibacterium acidipropionici P169, with a threshold of 10(4) CFU/U of dairy feed or rumen fluid...
  12. Cousin F, Jouan Lanhouet S, Dimanche Boitrel M, Corcos L, Jan G. Milk fermented by Propionibacterium freudenreichii induces apoptosis of HGT-1 human gastric cancer cells. PLoS ONE. 2012;7:e31892 pubmed publisher
    ..Such new probiotic fermented milk may thus be useful as part of a preventive diet designed to prevent gastric cancer and/or as a food supplement to potentiate cancer therapeutic treatments. ..
  13. Kiatpapan P, Murooka Y. Construction of an expression vector for propionibacteria and its use in production of 5-aminolevulinic acid by Propionibacterium freudenreichii. Appl Microbiol Biotechnol. 2001;56:144-9 pubmed
    Several promoters from Propionibacterium freudenreichii subsp. shermanii were isolated using a promoter probe vector, pCVE1, containing the Streptomyces cholesterol oxidase gene (choA) as a reporter gene...
  14. Anastasiou R, Leverrier P, Krestas I, Rouault A, Kalantzopoulos G, Boyaval P, et al. Changes in protein synthesis during thermal adaptation of Propionibacterium freudenreichii subsp. shermanii. Int J Food Microbiol. 2006;108:301-14 pubmed
    ..They were all found to belong to the Propionibacterium freudenreichii subsp. shermanii species...
  15. Sampedro M, Piper K, McDowell A, Patrick S, Mandrekar J, Rouse M, et al. Species of Propionibacterium and Propionibacterium acnes phylotypes associated with orthopedic implants. Diagn Microbiol Infect Dis. 2009;64:138-45 pubmed publisher
    b>Propionibacterium sp. is commonly isolated in association with orthopedic implants, either as a pathogen or a colonizer...
  16. Thierry A, Deutsch S, Falentin H, Dalmasso M, Cousin F, Jan G. New insights into physiology and metabolism of Propionibacterium freudenreichii. Int J Food Microbiol. 2011;149:19-27 pubmed publisher
    Dairy propionibacteria are Actinobacteria, mainly isolated from dairy environments. Propionibacterium freudenreichii has been used for a long time as a ripening culture in Swiss-type cheese manufacture, and is more and more considered ..
  17. Uchida M, Mogami O, Matsueda K. Characteristic of milk whey culture with Propionibacterium freudenreichii ET-3 and its application to the inflammatory bowel disease therapy. Inflammopharmacology. 2007;15:105-8 pubmed
    After the screening of microorganism culture, the culture of Propionibacterium freudenreichii ET-3 in the milk whey (milk whey culture) was found to stimulate the growth of our own Bifidobacteria in the colon but not the growth of other ..
  18. Stackebrandt E, Schumann P, Schaal K, Weiss N. Propionimicrobium gen. nov., a new genus to accommodate Propionibacterium lymphophilum (Torrey 1916) Johnson and Cummins 1972, 1057AL as Propionimicrobium lymphophilum comb. nov. Int J Syst Evol Microbiol. 2002;52:1925-7 pubmed
    ..of peptidoglycan, fatty acids and base composition of DNA, and supported by the phylogenetic position of the 165 rDNA sequence the species Propionibacterium lymphophilum was reclassified as Propionimicrobium lymphophilum comb. nov.
  19. Hervé C, Fondrevez M, Chéron A, Barloy Hubler F, Jan G. Transcarboxylase mRNA: a marker which evidences P. freudenreichii survival and metabolic activity during its transit in the human gut. Int J Food Microbiol. 2007;113:303-14 pubmed
    ..In addition, the development of efficient non-invasive methods which specifically monitor Propionibacterium freudenreichii concentration and activity within the human gut is required...
  20. Jan G, Belzacq A, Haouzi D, Rouault A, Metivier D, Kroemer G, et al. Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria. Cell Death Differ. 2002;9:179-88 pubmed
    The genus Propionibacterium is composed of dairy and cutaneous bacteria which produce short-chain fatty acids (SCFA), mainly propionate and acetate, by fermentation. Here, we show that P...
  21. Feng X, Chen F, Xu H, Wu B, Li H, Li S, et al. Green and economical production of propionic acid by Propionibacterium freudenreichii CCTCC M207015 in plant fibrous-bed bioreactor. Bioresour Technol. 2011;102:6141-6 pubmed publisher
    Propionic acid production by Propionibacterium freudenreichii from molasses and waste propionibacterium cells was studied in plant fibrous-bed bioreactor (PFB). With non-treated molasses as carbon source, 12.69 ± 0...
  22. Mak T, Yu S, De Marzo A, Bruggemann H, Sfanos K. Multilocus sequence typing (MLST) analysis of Propionibacterium acnes isolates from radical prostatectomy specimens. Prostate. 2013;73:770-7 pubmed publisher
    ..The pro-inflammatory anaerobe, Propionibacterium acnes, is ubiquitously found on human skin and is associated with the skin disease acne vulgaris...
  23. Zhang A, Yang S. Engineering Propionibacterium acidipropionici for enhanced propionic acid tolerance and fermentation. Biotechnol Bioeng. 2009;104:766-73 pubmed publisher
    b>Propionibacterium acidipropionici, a Gram-positive, anaerobic bacterium, has been the most used species for propionic acid production from sugars...
  24. Foligne B, Deutsch S, Breton J, Cousin F, Dewulf J, Samson M, et al. Promising immunomodulatory effects of selected strains of dairy propionibacteria as evidenced in vitro and in vivo. Appl Environ Microbiol. 2010;76:8259-64 pubmed publisher
    ..Two selected strains of Propionibacterium freudenreichii showed a protective effect against two models of colitis in mice, suggesting a probiotic ..
  25. Cardoso F, Gaspar P, Hugenholtz J, Ramos A, Santos H. Enhancement of trehalose production in dairy propionibacteria through manipulation of environmental conditions. Int J Food Microbiol. 2004;91:195-204 pubmed
    We have shown that the ability to produce trehalose is widespread within the genus Propionibacterium. Eighteen strains isolated from dairy sources were screened for trehalose synthesis; the effect of environmental conditions on trehalose ..
  26. Falentin H, Deutsch S, Jan G, Loux V, Thierry A, Parayre S, et al. The complete genome of Propionibacterium freudenreichii CIRM-BIA1, a hardy actinobacterium with food and probiotic applications. PLoS ONE. 2010;5:e11748 pubmed publisher
    b>Propionibacterium freudenreichii is essential as a ripening culture in Swiss-type cheeses and is also considered for its probiotic use. This species exhibits slow growth, low nutritional requirements, and hardiness in many habitats...
  27. Suwannakham S, Huang Y, Yang S. Construction and characterization of ack knock-out mutants of Propionibacterium acidipropionici for enhanced propionic acid fermentation. Biotechnol Bioeng. 2006;94:383-95 pubmed
    b>Propionibacterium acidipropionici produces propionic acid from glucose with acetic acid, succinic acid, and CO2 as byproducts...
  28. Meurice G, Deborde C, Jacob D, Falentin H, Boyaval P, Dimova D. In silico exploration of the fructose-6-phosphate phosphorylation step in glycolysis: genomic evidence of the coexistence of an atypical ATP-dependent along with a PPi-dependent phosphofructokinase in Propionibacterium freudenreichii subsp. shermanii. In Silico Biol. 2004;4:517-28 pubmed
    ..the catalytic step of fructose-6-phosphate phosphorylation in glycolysis based on the raw genomic draft of Propionibacterium freudenreichii subsp. shermanii (P. shermanii) ATCC9614 [Meurice et al., 2004]...
  29. Zappe B, Graf S, Ochsner P, Zimmerli W, Sendi P. Propionibacterium spp. in prosthetic joint infections: a diagnostic challenge. Arch Orthop Trauma Surg. 2008;128:1039-46 pubmed
    b>Propionibacterium species are common inhabitants of the skin and usually non-pathogenic for humans. However, Propionibacterium spp...
  30. Matte Tailliez O, Lepage E, Tenenhaus M, Tailliez P. Use of predictive modeling for Propionibacterium strain classification. Syst Appl Microbiol. 2002;25:386-95 pubmed
  31. Furuichi K, Katakura Y, Ninomiya K, Shioya S. Enhancement of 1,4-dihydroxy-2-naphthoic acid production by Propionibacterium freudenreichii ET-3 fed-batch culture. Appl Environ Microbiol. 2007;73:3137-43 pubmed
    The production of 1,4-dihydroxy-2-naphthoic acid (DHNA) was investigated using a fed-batch culture of Propionibacterium freudenreichii ET-3...
  32. Lan A, Lagadic Gossmann D, Lemaire C, Brenner C, Jan G. Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria. Apoptosis. 2007;12:573-91 pubmed
    The human probiotic Propionibacterium freudenreichii kills colorectal adenocarcinoma cells through apoptosis in vitro via its metabolites, the short chain fatty acids (SCFA), acetate and propionate...
  33. Ghorbani G, Morgavi D, Beauchemin K, Leedle J. Effects of bacterial direct-fed microbials on ruminal fermentation, blood variables, and the microbial populations of feedlot cattle. J Anim Sci. 2002;80:1977-85 pubmed
    ..Treatments were as follows: control, Propionibacterium P15 (P15), and Propionibacterium P15 and Enterococcus faecium EF212 (PE)...
  34. Lalani T, Person A, Hedayati S, Moore L, Murdoch D, Hoen B, et al. Propionibacterium endocarditis: a case series from the International Collaboration on Endocarditis Merged Database and Prospective Cohort Study. Scand J Infect Dis. 2007;39:840-8 pubmed
    b>Propionibacterium species are occasionally associated with serious systemic infections such as infective endocarditis...
  35. Lan A, Bruneau A, Bensaada M, Philippe C, Bellaud P, Rabot S, et al. Increased induction of apoptosis by Propionibacterium freudenreichii TL133 in colonic mucosal crypts of human microbiota-associated rats treated with 1,2-dimethylhydrazine. Br J Nutr. 2008;100:1251-9 pubmed publisher
    b>Propionibacterium freudenreichii, a food-grade bacterium able to kill colon cancer cell lines in vitro by apoptosis, may exert an anticarcinogenic effect in vivo...
  36. Myllyluoma E, Ahonen A, Korpela R, Vapaatalo H, Kankuri E. Effects of multispecies probiotic combination on helicobacter pylori infection in vitro. Clin Vaccine Immunol. 2008;15:1472-82 pubmed publisher
    ..pylori-infected Caco-2 cells were pretreated with Lactobacillus rhamnosus GG, Lactobacillus rhamnosus Lc705, Propionibacterium freudenreichii subsp. shermanii Js, Bifidobacterium breve Bb99, or all four organisms in combination...
  37. Sohail M, Gray A, Baddour L, Tleyjeh I, Virk A. Infective endocarditis due to Propionibacterium species. Clin Microbiol Infect. 2009;15:387-94 pubmed publisher
    b>Propionibacterium species rarely cause infective endocarditis. When identified in blood cultures, they may be inappropriately disregarded as skin flora contaminants...
  38. Deutsch S, Le Bivic P, Hervé C, Madec M, LaPointe G, Jan G, et al. Correlation of the capsular phenotype in Propionibacterium freudenreichii with the level of expression of gtf, a unique polysaccharide synthase-encoding gene. Appl Environ Microbiol. 2010;76:2740-6 pubmed publisher
    ..b>Propionibacterium freudenreichii is a Gram-positive food-grade bacterium with reported probiotic capabilities that is widely ..
  39. Goldstein E, Citron D, Merriam C, Warren Y, Tyrrell K, Fernandez H. Comparative in vitro activities of retapamulin (SB-275833) against 141 clinical isolates of Propionibacterium spp., including 117 P. acnes isolates. Antimicrob Agents Chemother. 2006;50:379-81 pubmed
    ..method, we studied the in vitro activity of retapamulin (SB-275833) against 141 clinical isolates of Propionibacterium species, including seven multiresistant strains, and found retapamulin to be the most active agent among ..
  40. Carvalho A, Cardoso F, Bohn A, Neves A, Santos H. Engineering trehalose synthesis in Lactococcus lactis for improved stress tolerance. Appl Environ Microbiol. 2011;77:4189-99 pubmed publisher
    ..In particular, our team detected high levels of trehalose in Propionibacterium freudenreichii in response to acid stress, a result that led to the idea that endowing Lactococcus lactis ..
  41. Butler Wu S, Sengupta D, Kittichotirat W, Matsen F, Bumgarner R. Genome sequence of a novel species, Propionibacterium humerusii. J Bacteriol. 2011;193:3678 pubmed publisher
    As part of a larger project to sequence multiple clinical isolates of Propionibacterium acnes, we have produced a draft genome sequence of a novel Propionibacterium species that is closely related to, yet distinct (by sequence) from P...
  42. Thierry A, Maillard M, Yvon M. Conversion of L-leucine to isovaleric acid by Propionibacterium freudenreichii TL 34 and ITGP23. Appl Environ Microbiol. 2002;68:608-15 pubmed
    ..Our aim was to determine the ability of Propionibacterium freudenreichii, which is one of the main components of the secondary flora of Swiss cheese, to produce ..
  43. El Nezami H, Chrevatidis A, Auriola S, Salminen S, Mykkanen H. Removal of common Fusarium toxins in vitro by strains of Lactobacillus and Propionibacterium. Food Addit Contam. 2002;19:680-6 pubmed
    This study was conducted to examine the ability of selected strains of Lactobacillus and Propionibacterium to remove common Fusarium toxins, trichothecenes, from liquid media...
  44. Elam N, Gleghorn J, Rivera J, Galyean M, Defoor P, Brashears M, et al. Effects of live cultures of Lactobacillus acidophilus (strains NP45 and NP51) and Propionibacterium freudenreichii on performance, carcass, and intestinal characteristics, and Escherichia coli strain O157 shedding of finishing beef steers. J Anim Sci. 2003;81:2686-98 pubmed
    ..8 kg) were used to determine the effects of Lactobacillus acidophilus (LA) plus Propionibacterium freudenreichii (PF) on performance, carcass, and intestinal characteristics; serum IgA concentrations; and ..
  45. Dishisha T, Alvarez M, Hatti Kaul R. Batch- and continuous propionic acid production from glycerol using free and immobilized cells of Propionibacterium acidipropionici. Bioresour Technol. 2012;118:553-62 pubmed publisher
    Propionic acid production from glycerol was studied using Propionibacterium acidipropionici DSM 4900 cells immobilized on polyethylenimine-treated Poraver (PEI-Poraver) and Luffa (PEI-Luffa), respectively...
  46. Balogun R, Palmisano J, Kaplan A, Khurshid H, Yamase H, Adams N. Shunt nephritis from Propionibacterium acnes in a solitary kidney. Am J Kidney Dis. 2001;38:E18 pubmed
    ..is Staphylococcus epidermidis, but less often, an organism generally regarded as nonpathogenic, such as Propionibacterium acnes, has been noted as the cause...
  47. Dalmasso M, Aubert J, Briard Bion V, Chuat V, Deutsch S, Even S, et al. A temporal-omic study of Propionibacterium freudenreichii CIRM-BIA1 adaptation strategies in conditions mimicking cheese ripening in the cold. PLoS ONE. 2012;7:e29083 pubmed publisher
    b>Propionibacterium freudenreichii is used as a ripening culture in Swiss cheese manufacture. It grows when cheeses are ripened in a warm room (about 24°C)...
  48. Kośmider A, Białas W, Kubiak P, Drożdżyńska A, Czaczyk K. Vitamin B12 production from crude glycerol by Propionibacterium freudenreichii ssp. shermanii: optimization of medium composition through statistical experimental designs. Bioresour Technol. 2012;105:128-33 pubmed publisher
    ..experimental design was employed to optimize the medium for vitamin B(12) production from crude glycerol by Propionibacterium freudenreichii ssp. shermanii...
  49. Goswami V, Srivastava A. Propionic acid production in an in situ cell retention bioreactor. Appl Microbiol Biotechnol. 2001;56:676-80 pubmed
    ..situ cell retention using spin filters (pore size 5 microm and 10 microm) for propionic acid production by Propionibacterium acidipropionici...
  50. Raeth Knight M, Linn J, Jung H. Effect of direct-fed microbials on performance, diet digestibility, and rumen characteristics of Holstein dairy cows. J Dairy Sci. 2007;90:1802-9 pubmed
    ..Under the conditions of these studies, supplementing midlactation cows with DFM products containing L. acidophilus and P. freudenreichii did not affect cow performance, diet digestibility, or rumen fermentation...
  51. Gorret N, Maubois J, Engasser J, Ghoul M. Study of the effects of temperature, pH and yeast extract on growth and exopolysaccharides production by Propionibacterium acidi-propionici on milk microfiltrate using a response surface methodology. J Appl Microbiol. 2001;90:788-96 pubmed
    To study the effects of temperature, pH and yeast extract (YE) concentration on growth and exopolysaccharide (EPS) production by Propionibacterium acidi-propionici DSM 4900 cultivated on milk microfiltrate.
  52. Falentin H, Postollec F, Parayre S, Henaff N, Le Bivic P, Richoux R, et al. Specific metabolic activity of ripening bacteria quantified by real-time reverse transcription PCR throughout Emmental cheese manufacture. Int J Food Microbiol. 2010;144:10-9 pubmed publisher
    ..activity and the stress level of the two species used as ripening cultures in Emmental cheese manufacture, Propionibacterium freudenreichii and Lactobacillus paracasei...
  53. Dherbecourt J, Falentin H, Jardin J, Maillard M, Baglinière F, Barloy Hubler F, et al. Identification of a secreted lipolytic esterase in Propionibacterium freudenreichii, a ripening process bacterium involved in Emmental cheese lipolysis. Appl Environ Microbiol. 2010;76:1181-8 pubmed publisher
    ..In Emmental cheese, the main part of lipolysis has been associated with the presence of Propionibacterium freudenreichii, a species used as a ripening culture...
  54. Parizzi L, Grassi M, Llerena L, Carazzolle M, Queiroz V, Lunardi I, et al. The genome sequence of Propionibacterium acidipropionici provides insights into its biotechnological and industrial potential. BMC Genomics. 2012;13:562 pubmed publisher
    ..In this work we analyzed the genome of the propionic acid producer Actinobacteria Propionibacterium acidipropionici (ATCC 4875).
  55. Faye T, Brede D, Langsrud T, Nes I, Holo H. An antimicrobial peptide is produced by extracellular processing of a protein from Propionibacterium jensenii. J Bacteriol. 2002;184:3649-56 pubmed
    ..antimicrobial peptide (PAMP) and its inactive precursor were purified from the culture supernatant of Propionibacterium jensenii LMG 3032 and characterized at the molecular level...
  56. del Pozo J, Tran N, Petty P, Johnson C, Walsh M, Bite U, et al. Pilot study of association of bacteria on breast implants with capsular contracture. J Clin Microbiol. 2009;47:1333-7 pubmed publisher
    ..034). Propionibacterium species, coagulase-negative staphylococci, and Corynebacterium species were the microorganisms isolated...
  57. Roessner C, Huang K, Warren M, Raux E, Scott A. Isolation and characterization of 14 additional genes specifying the anaerobic biosynthesis of cobalamin (vitamin B12) in Propionibacterium freudenreichii (P. shermanii). Microbiology. 2002;148:1845-53 pubmed
    ..genes encoding enzymes involved in cobalamin (vitamin B12) production in the commercially important organism Propionibacterium freudenreichii (P...
  58. Clayton J, Baig W, Reynolds G, Sandoe J. Endocarditis caused by Propionibacterium species: a report of three cases and a review of clinical features and diagnostic difficulties. J Med Microbiol. 2006;55:981-7 pubmed
    b>Propionibacterium species are members of the normal flora of skin and the mouth but their pathogenic potential is often overlooked...
  59. Dalmasso M, Aubert J, Even S, Falentin H, Maillard M, Parayre S, et al. Accumulation of intracellular glycogen and trehalose by Propionibacterium freudenreichii under conditions mimicking cheese ripening in the cold. Appl Environ Microbiol. 2012;78:6357-64 pubmed publisher
    Seven Propionibacterium freudenreichii strains exhibited similar responses when placed at 4°C...
  60. Luo J, King S, Adams M. Effect of probiotic Propionibacterium jensenii 702 supplementation on layer chicken performance. Benef Microbes. 2010;1:53-60 pubmed publisher
    The effects of the probiotic, Propionibacterium jensenii 702 (PJ 702), supplementation on egg productivity, egg shell thickness, fatty acid profile of eggs, and body weight in early layer hens were investigated...
  61. Isawa K, Hojo K, Yoda N, Kamiyama T, Makino S, Saito M, et al. Isolation and identification of a new bifidogenic growth stimulator produced by Propionibacterium freudenreichii ET-3. Biosci Biotechnol Biochem. 2002;66:679-81 pubmed
    We have found a new growth stimulator for bifidobacteria in the culture broth of Propionibacterium freudenreichii ET-3. The bifidogenic growth stimulator (BGS) was purified by Diaion HP-20 column chromatography and preparative HPLC...
  62. Ruhal R, Choudhury B. Improved trehalose production from biodiesel waste using parent and osmotically sensitive mutant of Propionibacterium freudenreichii subsp. shermanii under aerobic conditions. J Ind Microbiol Biotechnol. 2012;39:1153-60 pubmed publisher
    ..Recently, crude glycerol was reported to be suitable for the production of trehalose using a food microbe, Propionibacterium freudenreichii subsp. shermanii, under static flask conditions...
  63. Saxelin M, Lassig A, Karjalainen H, Tynkkynen S, Surakka A, Vapaatalo H, et al. Persistence of probiotic strains in the gastrointestinal tract when administered as capsules, yoghurt, or cheese. Int J Food Microbiol. 2010;144:293-300 pubmed publisher
    ..faecal recovery during and after administration of a combination of Lactobacillus rhamnosus GG and LC705, Propionibacterium freudenreichii subsp. shermanii JS, and Bifidobacterium animalis subsp...
  64. Kato Mori Y, Orihashi T, Kanai Y, Sato M, Sera K, Hagiwara K. Fermentation metabolites from Lactobacillus gasseri and Propionibacterium freudenreichii exert bacteriocidal effects in mice. J Med Food. 2010;13:1460-7 pubmed publisher
    ..On the other hand, milk whey fermented by Propionibacterium freudenreichii ET-3, which increases the numbers of Bifidobacterium, is effective for intestinal disorders...
  65. Zárate G, Morata De Ambrosini V, Perez Chaia A, Gonzalez S. Some factors affecting the adherence of probiotic Propionibacterium acidipropionici CRL 1198 to intestinal epithelial cells. Can J Microbiol. 2002;48:449-57 pubmed
    ..This study investigated some factors that could affect or be involved in the adherence of Propionibacterium acidipropionici CRL 1198, a dairy strain with suggested probiotic effects and high adherence in vitro and in ..
  66. Lan A, Bruneau A, Philippe C, Rochet V, Rouault A, Hervé C, et al. Survival and metabolic activity of selected strains of Propionibacterium freudenreichii in the gastrointestinal tract of human microbiota-associated rats. Br J Nutr. 2007;97:714-24 pubmed
    ..The aim of the present study was to investigate the survival and metabolic activity of Propionibacterium freudenreichii within the gastrointestinal tract of human microbiota-associated rats, and its influence on ..
  67. Coral J, Karp S, Porto de Souza Vandenberghe L, Parada J, Pandey A, Soccol C. Batch fermentation model of propionic acid production by Propionibacterium acidipropionici in different carbon sources. Appl Biochem Biotechnol. 2008;151:333-41 pubmed publisher
    ..In the present investigation, PA production by Propionibacterium acidipropionici ATCC 4965 was studied using a basal medium with sugarcane molasses (BMSM), glycerol or ..
  68. Miescher S, Stierli M, Teuber M, Meile L. Propionicin SM1, a bacteriocin from Propionibacterium jensenii DF1: isolation and characterization of the protein and its gene. Syst Appl Microbiol. 2000;23:174-84 pubmed publisher
    We purified a bacteriocin from the cell-free supernatant of Propionibacterium jensenii DF1 isolated from Swiss raw milk, and named it propionicin SM1. The heat-stable protein was strongly bactericidal against P. jensenii DSM20274...
  69. Panagea S, Corkill J, Hershman M, Parry C. Breast abscess caused by Propionibacterium avidum following breast reduction surgery: case report and review of the literature. J Infect. 2005;51:e253-5 pubmed
    b>Propionibacterium avidum was isolated from bilateral breast abscesses following breast reduction surgery. This report highlights the potential pathogenicity of the normal microbial flora following surgical interventions.
  70. Leverrier P, Dimova D, Pichereau V, Auffray Y, Boyaval P, Jan G. Susceptibility and adaptive response to bile salts in Propionibacterium freudenreichii: physiological and proteomic analysis. Appl Environ Microbiol. 2003;69:3809-18 pubmed
    ..Susceptibility to bile salts and tolerance acquisition in the probiotic strain Propionibacterium freudenreichii SI41 were characterized...
  71. Leverrier P, Vissers J, Rouault A, Boyaval P, Jan G. Mass spectrometry proteomic analysis of stress adaptation reveals both common and distinct response pathways in Propionibacterium freudenreichii. Arch Microbiol. 2004;181:215-30 pubmed
    ..Stress tolerance and cross-protection in Propionibacterium freudenreichii were thus examined after exposure to heat, acid, or bile salts stresses...
  72. Liu Z, Ma C, Gao C, Xu P. Efficient utilization of hemicellulose hydrolysate for propionic acid production using Propionibacterium acidipropionici. Bioresour Technol. 2012;114:711-4 pubmed publisher
    ..In this study, propionic acid production from glucose, xylose, or arabinose using Propionibacterium acidipropionici ATCC 4875 was investigated...
  73. van der Merwe I, Bauer R, Britz T, Dicks L. Characterization of thoeniicin 447, a bacteriocin isolated from Propionibacterium thoenii strain 447. Int J Food Microbiol. 2004;92:153-60 pubmed
    ..b>Propionibacterium thoenii 447 produced an antimicrobial peptide, thoeniicin 447, which acted bactericidal against ..
  74. Jan G, Leverrier P, Pichereau V, Boyaval P. Changes in protein synthesis and morphology during acid adaptation of Propionibacterium freudenreichii. Appl Environ Microbiol. 2001;67:2029-36 pubmed
    ..Acid stress adaptation in the probiotic SI41 strain of Propionibacterium freudenreichii was therefore investigated...
  75. Okada Y, Tsuzuki Y, Miyazaki J, Matsuzaki K, Hokari R, Komoto S, et al. Propionibacterium freudenreichii component 1.4-dihydroxy-2-naphthoic acid (DHNA) attenuates dextran sodium sulphate induced colitis by modulation of bacterial flora and lymphocyte homing. Gut. 2006;55:681-8 pubmed
    1.4-Dihydroxy-2-naphthoic acid (DHNA), a bifidogenic growth stimulator from Propionibacterium freudenreichii, is thought to have a beneficial effect as a prebiotic; however, its in vivo effect on intestinal inflammation remains unknown...
  76. Uchida M, Mogami O. Milk whey culture with Propionibacterium freudenreichii ET-3 is effective on the colitis induced by 2,4,6-trinitrobenzene sulfonic acid in rats. J Pharmacol Sci. 2005;99:329-34 pubmed
    ..The above results show that milk whey culture may become a useful prebiotic for the therapy of inflammatory bowel disease and that propionic acid may be one of the active substances contained in milk whey culture...
  77. Moussavi M, Adams M. An in vitro study on bacterial growth interactions and intestinal epithelial cell adhesion characteristics of probiotic combinations. Curr Microbiol. 2010;60:327-35 pubmed publisher
    ..GG, Lactobacillus reuteri ATCC 55730 and Bifidobacterium lactis Bb12) either alone or in combination with Propionibacterium jensenii 702 in a co-culture system and to determine their adhesion ability to human colon adenocarcinoma ..
  78. Hatakka K, Mutanen M, Holma R, Saxelin M, Korpela R. Lactobacillus rhamnosus LC705 together with Propionibacterium freudenreichii ssp shermanii JS administered in capsules is ineffective in lowering serum lipids. J Am Coll Nutr. 2008;27:441-7 pubmed
    ..of this study was to examine the effect of the administration of Lactobacillus rhamnosus strain LC705 and Propionibacterium freudenreichii ssp shermanii strain JS in capsules on serum cholesterol and triglyceride levels in mildly or ..
  79. Chopin M, Rouault A, Ehrlich S, Gautier M. Filamentous phage active on the gram-positive bacterium Propionibacterium freudenreichii. J Bacteriol. 2002;184:2030-3 pubmed
    ..Phage B5 infects Propionibacterium freudenreichii and has a genome consisting of 5,806 bases coding for 10 putative open reading frames...
  80. Brede D, Faye T, Johnsborg O, Odegård I, Nes I, Holo H. Molecular and genetic characterization of propionicin F, a bacteriocin from Propionibacterium freudenreichii. Appl Environ Microbiol. 2004;70:7303-10 pubmed
    ..work describes the purification and characterization of propionicin F, the first bacteriocin isolated from Propionibacterium freudenreichii. The bacteriocin has a bactericidal activity and is only active against strains of P...
  81. Hall P, Zheng R, Antony L, Pusztai Carey M, Carey P, Yee V. Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. EMBO J. 2004;23:3621-31 pubmed
    Transcarboxylase is a 1.2 million Dalton (Da) multienzyme complex from Propionibacterium shermanii that couples two carboxylation reactions, transferring CO(2)(-) from methylmalonyl-CoA to pyruvate to yield propionyl-CoA and oxaloacetate...
  82. Ruhal R, Choudhury B. Use of an osmotically sensitive mutant of Propionibacterium freudenreichii subspp. shermanii for the simultaneous productions of organic acids and trehalose from biodiesel waste based crude glycerol. Bioresour Technol. 2012;109:131-9 pubmed publisher
    Recently suitability of crude glycerol for trehalose and propionic acid productions was reported using Propionibacterium freudenreichii subspp...
  83. Mohammadi T, Reesink H, Pietersz R, Vandenbroucke Grauls C, Savelkoul P. Amplified-fragment length polymorphism analysis of Propionibacterium isolates implicated in contamination of blood products. Br J Haematol. 2005;131:403-9 pubmed
    b>Propionibacterium acnes is implicated in most cases of bacterial contamination of platelet concentrates (PCs). To determine the source of contamination, amplified-fragment length polymorphism (AFLP) analysis was applied...
  84. Gardner N, Champagne C. Production of Propionibacterium shermanii biomass and vitamin B12 on spent media. J Appl Microbiol. 2005;99:1236-45 pubmed
    ..This study was designed to examine the possibility of using spent media previously used to grow LAB for the production of biomass and metabolites of Propionibacterium freudenreichii subsp. shermanii.
  85. Delgado S, Suarez A, Mayo B. Identification, typing and characterisation of Propionibacterium strains from healthy mucosa of the human stomach. Int J Food Microbiol. 2011;149:65-72 pubmed publisher
    Forty two Propionibacterium isolates were recovered from biopsy samples of the gastric mucosa of eight out of 12 healthy people...
  86. Gratz S, Mykkanen H, El Nezami H. Aflatoxin B1 binding by a mixture of Lactobacillus and Propionibacterium: in vitro versus ex vivo. J Food Prot. 2005;68:2470-4 pubmed
    ..Several probiotic bacteria are able to bind AFB1 in vitro, including Lactobacillus rhamnosus LC-705 and Propionibacterium freudenreichii subsp. shermanii JS...
  87. Cardoso F, Castro R, Borges N, Santos H. Biochemical and genetic characterization of the pathways for trehalose metabolism in Propionibacterium freudenreichii, and their role in stress response. Microbiology. 2007;153:270-80 pubmed
    b>Propionibacterium freudenreichii accumulates high levels of trehalose, especially in response to stress...
  88. Deutsch S, Falentin H, Dols Lafargue M, LaPointe G, Roy D. Capsular exopolysaccharide biosynthesis gene of Propionibacterium freudenreichii subsp. shermanii. Int J Food Microbiol. 2008;125:252-8 pubmed publisher
    ..A polysaccharide synthase-encoding gene was identified in the genome of Propionibacterium freudenreichii subsp. shermanii TL 34 (CIP 103027)...
  89. Suwannakham S, Yang S. Enhanced propionic acid fermentation by Propionibacterium acidipropionici mutant obtained by adaptation in a fibrous-bed bioreactor. Biotechnol Bioeng. 2005;91:325-37 pubmed
    ..acidipropionici was thus attributed to both a high viable cell density maintained in the reactor and favorable mutations resulted from adaptation by cell immobilization in the FBB...