actinomyces

Summary

Summary: A genus of gram-positive, rod-shaped bacteria whose organisms are nonmotile. Filaments that may be present in certain species are either straight or wavy and may have swollen or clubbed heads.

Top Publications

  1. Smith A, Hall V, Thakker B, Gemmell C. Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents. J Antimicrob Chemother. 2005;56:407-9 pubmed
    This study was conducted to assess the susceptibility of human clinical isolates of Actinomyces species to 12 antimicrobial agents.
  2. Hermida M, Della Giovanna P, Lapadula M, Garcia S, Cabrera H. Actinomyces meyeri cutaneous actinomycosis. Int J Dermatol. 2009;48:154-6 pubmed publisher
    b>Actinomyces meyeri cutaneous actinomycosis is a very rare disease. It often results from contiguous dissemination of an underlying focus...
  3. Wang G, Zhang H, Sun G, Wu L, Zhang J, Wang Y. A new method for rapid identification of ansamycin compounds by inactivating KLM gene clusters in potential ansamycin-producing actinomyces. J Appl Microbiol. 2012;112:353-62 pubmed publisher
  4. Barbour M, O Sullivan D, Jenkinson H, Jagger D. The effects of polishing methods on surface morphology, roughness and bacterial colonisation of titanium abutments. J Mater Sci Mater Med. 2007;18:1439-47 pubmed
    ..Biofilms of Actinomyces naeslundii were more extensive on polished abutment surfaces...
  5. Busscher H, Jager D, Finger G, Schaefer N, van der Mei H. Energy transfer, volumetric expansion, and removal of oral biofilms by non-contact brushing. Eur J Oral Sci. 2010;118:177-82 pubmed publisher
    ..e. at the limiting distance for non-contact removal), biofilm is expanded but not removed...
  6. van der Mei H, Rustema Abbing M, Bruinsma G, Gottenbos B, Busscher H. Sequence of oral bacterial co-adhesion and non-contact brushing. J Dent Res. 2007;86:421-5 pubmed
    ..A pair of co-adhering streptococci and actinomyces has been used previously to demonstrate non-contact removal by sonic brushing...
  7. Hou Y, Wang Q, Ding L, Li F, Qin S. attB site disruption in marine Actinomyces sp. M048 via DNA transformation of a site-specific integration vector. Biotechnol Appl Biochem. 2008;50:11-6 pubmed
    An efficient conjugation method has been developed for the marine Actinomyces sp. isolate M048 to facilitate the genetic manipulation of the chandrananimycin biosynthesis gene cluster...
  8. Renvoise A, Raoult D, Roux V. Actinomyces timonensis sp. nov., isolated from a human clinical osteo-articular sample. Int J Syst Evol Microbiol. 2010;60:1516-21 pubmed publisher
    ..and the results of biochemical analysis, this strain was tentatively identified as a novel species of the genus Actinomyces. Phylogenetic analysis based on 16S rRNA gene sequence comparisons showed that the bacterium was closely ..
  9. Delisle A, Barcak G, Guo M. Isolation and expression of the lysis genes of Actinomyces naeslundii phage Av-1. Appl Environ Microbiol. 2006;72:1110-7 pubmed publisher
    Like most gram-positive oral bacteria, Actinomyces naeslundii is resistant to salivary lysozyme and to most other lytic enzymes...

More Information

Publications74

  1. Henssge U, Do T, Radford D, Gilbert S, Clark D, Beighton D. Emended description of Actinomyces naeslundii and descriptions of Actinomyces oris sp. nov. and Actinomyces johnsonii sp. nov., previously identified as Actinomyces naeslundii genospecies 1, 2 and WVA 963. Int J Syst Evol Microbiol. 2009;59:509-16 pubmed publisher
    b>Actinomyces naeslundii is an important early colonizer in the oral biofilm and consists of three genospecies (1, 2 and WVA 963) which cannot be readily differentiated using conventional phenotypic testing or on the basis of 16S rRNA gene ..
  2. Zhang S, Qiu J, Tian F, Guo X, Zhang F, Huang Q. Corrosion behavior of pure titanium in the presence of Actinomyces naeslundii. J Mater Sci Mater Med. 2013;24:1229-37 pubmed publisher
    It is well known that some microorganisms affect the corrosion of dental metal. Oral bacteria such as Actinomyces naeslundii may alter the corrosion behavior and stability of titanium...
  3. Kolenbrander P, Palmer R, Rickard A, Jakubovics N, Chalmers N, Diaz P. Bacterial interactions and successions during plaque development. Periodontol 2000. 2006;42:47-79 pubmed
  4. Mishra A, Das A, Cisar J, Ton That H. Sortase-catalyzed assembly of distinct heteromeric fimbriae in Actinomyces naeslundii. J Bacteriol. 2007;189:3156-65 pubmed
    Two types of adhesive fimbriae are expressed by Actinomyces; however, the architecture and the mechanism of assembly of these structures remain poorly understood...
  5. Richman M, Jeng A. Intra-abdominal co-infection with Mycobacterium bovis and Actinomyces in an AIDS patient: the first reported case and review. J Infect. 2007;55:e115-8 pubmed
    The Mycobacterium tuberculous complex and Actinomyces can both cause indolent intra-abdominal infections that result in hard mass lesion(s), oftentimes fixed to underlying tissue and involving the right ileocecal fossa region...
  6. Wickstrom C, Svensater G. Salivary gel-forming mucin MUC5B--a nutrient for dental plaque bacteria. Oral Microbiol Immunol. 2008;23:177-82 pubmed publisher
  7. Funke G, Englert R, Frodl R, Bernard K, Stenger S. Actinomyces hominis sp. nov., isolated from a wound swab. Int J Syst Evol Microbiol. 2010;60:1678-81 pubmed publisher
    ..Chemotaxonomic investigations suggested that this bacterium was related to the genera Actinomyces, Arcanobacterium and Actinobaculum...
  8. von Graevenitz A. Actinomyces neuii: review of an unusual infectious agent. Infection. 2011;39:97-100 pubmed publisher
    b>Actinomyces neuii, a species first described in 1994, has proven to be an exception in this genus on account of its aerobic growth, microscopic morphology (no branching), and the types and location of infections...
  9. Liy Y, Yaling L, Dan J, Tao H, Xuedong Z. Regulation of urease expression of Actinomyces naeslundii in biofilms in response to pH and carbohydrate. Oral Microbiol Immunol. 2008;23:315-9 pubmed publisher
    ..b>Actinomyces naeslundii is a ureolytic bacterium that is adapted to tolerate the rapid and dramatic fluctuations in nutrient ..
  10. Periasamy S, Chalmers N, Du Thumm L, Kolenbrander P. Fusobacterium nucleatum ATCC 10953 requires Actinomyces naeslundii ATCC 43146 for growth on saliva in a three-species community that includes Streptococcus oralis 34. Appl Environ Microbiol. 2009;75:3250-7 pubmed publisher
    ..in dental plaque, but they become prevalent after the initial commensal colonizers, such as streptococci and actinomyces, have established communities...
  11. Hall V. Actinomyces--gathering evidence of human colonization and infection. Anaerobe. 2008;14:1-7 pubmed publisher
    The roles of the 'classical'Actinomyces spp. as colonizers of oral cavities of man and animals, in development of intra-oral infections and as agents of actinomycosis have been well documented...
  12. Moelling C, Oberschlacke R, Ward P, Karijolich J, Borisova K, Bjelos N, et al. Metal-dependent repression of siderophore and biofilm formation in Actinomyces naeslundii. FEMS Microbiol Lett. 2007;275:214-20 pubmed
    b>Actinomyces naeslundii is a pioneer of the oral cavity and forms a biofilm on the tooth's surface. Most bacteria require iron for survival and in pathogenic bacteria iron availability regulates virulence gene expression...
  13. Dige I, Raarup M, Nyengaard J, Kilian M, Nyvad B. Actinomyces naeslundii in initial dental biofilm formation. Microbiology. 2009;155:2116-26 pubmed publisher
    ..The purpose of this study was to analyse the patterns of colonization and population dynamics of Actinomyces naeslundii compared to streptococci and other bacteria during the initial 48 h of biofilm formation in the oral ..
  14. Horiuchi M, Washio J, Mayanagi H, Takahashi N. Transient acid-impairment of growth ability of oral Streptococcus, Actinomyces, and Lactobacillus: a possible ecological determinant in dental plaque. Oral Microbiol Immunol. 2009;24:319-24 pubmed publisher
    ..We, therefore, investigated the effects of physiological acidification on representative caries-related bacteria...
  15. Rieber H, Schwarz R, Krämer O, Cordier W, Frommelt L. Actinomyces neuii subsp. neuii Associated with periprosthetic infection in total hip arthroplasty as causative agent. J Clin Microbiol. 2009;47:4183-4 pubmed publisher
    b>Actinomyces neuii has until now not been described as a pathogen associated with periprosthetic infection in total joint replacement. The case presented here suggests that A. neuii subsp. neuii is a causative pathogen...
  16. Al Ahmad A, Wunder A, Auschill T, Follo M, Braun G, Hellwig E, et al. The in vivo dynamics of Streptococcus spp., Actinomyces naeslundii, Fusobacterium nucleatum and Veillonella spp. in dental plaque biofilm as analysed by five-colour multiplex fluorescence in situ hybridization. J Med Microbiol. 2007;56:681-7 pubmed
    ..0006). The decreases of Actinomyces naeslundii content on day 2 and day 7 were significant (P=0.0028). Changes in Veillonella spp...
  17. Takahashi N, Nyvad B. The role of bacteria in the caries process: ecological perspectives. J Dent Res. 2011;90:294-303 pubmed publisher
    ..The microflora on clinically sound enamel surfaces contains mainly non-mutans streptococci and Actinomyces, in which acidification is mild and infrequent...
  18. Hansen T, Wagner W, Kirkpatrick C, Kunkel M. Infected osteoradionecrosis of the mandible: follow-up study suggests deterioration in outcome for patients with Actinomyces-positive bone biopsies. Int J Oral Maxillofac Surg. 2006;35:1001-4 pubmed
    ..Recent studies showed a high prevalence of Actinomyces in IORN...
  19. Drobni M, Li T, Krüger C, Loimaranta V, Kilian M, Hammarstrom L, et al. Host-derived pentapeptide affecting adhesion, proliferation, and local pH in biofilm communities composed of Streptococcus and Actinomyces species. Infect Immun. 2006;74:6293-9 pubmed
    Salivary proline-rich proteins (PRPs) attach commensal Actinomyces and Streptococcus species to teeth...
  20. Westhoff C. IUDs and colonization or infection with Actinomyces. Contraception. 2007;75:S48-50 pubmed
    ..Approximately 7% of women using an IUD may have a finding of Actinomyces-like organisms on a Pap test...
  21. Diaz P, Chalmers N, Rickard A, Kong C, Milburn C, Palmer R, et al. Molecular characterization of subject-specific oral microflora during initial colonization of enamel. Appl Environ Microbiol. 2006;72:2837-48 pubmed
    ..observed genera (comprising at least 5% of clone sequences in at least one of the six clone libraries) were Actinomyces, Gemella, Granulicatella, Neisseria, Prevotella, Rothia, and Veillonella...
  22. Persson K. Structure of the sortase AcSrtC-1 from Actinomyces oris. Acta Crystallogr D Biol Crystallogr. 2011;67:212-7 pubmed publisher
    The crystal structure of the sortase AcSrtC-1 from the oral microorganism Actinomyces oris has been determined to 2.4?Å resolution...
  23. Drobni M, Hallberg K, Ohman U, Birve A, Persson K, Johansson I, et al. Sequence analyses of fimbriae subunit FimA proteins on Actinomyces naeslundii genospecies 1 and 2 and Actinomyces odontolyticus with variant carbohydrate binding specificities. BMC Microbiol. 2006;6:43 pubmed
    b>Actinomyces naeslundii genospecies 1 and 2 express type-2 fimbriae (FimA subunit polymers) with variant Galbeta binding specificities and Actinomyces odontolyticus a sialic acid specificity to colonize different oral surfaces...
  24. Wu C, Mishra A, Yang J, Cisar J, Das A, Ton That H. Dual function of a tip fimbrillin of Actinomyces in fimbrial assembly and receptor binding. J Bacteriol. 2011;193:3197-206 pubmed publisher
    Interaction of Actinomyces oris with salivary proline-rich proteins (PRPs), which serve as fimbrial receptors, involves type 1 fimbriae...
  25. Naik N, Russo T. Bisphosphonate-related osteonecrosis of the jaw: the role of actinomyces. Clin Infect Dis. 2009;49:1729-32 pubmed publisher
    ..Bisphosphonates may not be the primary cause. Actinomyces are an underrecognized agent in pathogenesis, and timely actinomycosis-specific treatment may improve outcome.
  26. Chen P, Cisar J, Hess S, Ho J, Leung K. Amended description of the genes for synthesis of Actinomyces naeslundii T14V type 1 fimbriae and associated adhesin. Infect Immun. 2007;75:4181-5 pubmed
    The type 1 fimbriae of Actinomyces naeslundii T14V mediate adhesion of this gram-positive species to the tooth surface...
  27. Mishra A, Devarajan B, Reardon M, Dwivedi P, Krishnan V, Cisar J, et al. Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development. Mol Microbiol. 2011;81:1205-20 pubmed publisher
    ..modelling, we describe here the atomic structure of distinct adhesive moieties of FimA, the shaft fimbrillin of Actinomyces type 2 fimbriae, which uniquely mediates the receptor-dependent intercellular interactions between Actinomyces ..
  28. Valko P, Busolini E, Donati N, Chimchila Chevili S, Rusca T, Bernasconi E. Severe large bowel obstruction secondary to infection with Actinomyces israelii. Scand J Infect Dis. 2006;38:231-4 pubmed
    ..We report on a 38-y-old female with abdomino-pelvic actinomycosis, characterized by a 10 cm long filiform stenosis of the sigmoid colon and bilateral ovarian abscesses. She developed acute ileus that required emergency surgery...
  29. Chu C, Mei L, Seneviratne C, Lo E. Effects of silver diamine fluoride on dentine carious lesions induced by Streptococcus mutans and Actinomyces naeslundii biofilms. Int J Paediatr Dent. 2012;22:2-10 pubmed publisher
    ..AIM. To characterize the effects of SDF on dentine carious induced by Streptococcus mutans and Actinomyces naeslundii. DESIGN.? Thirty-two artificially demineralized human dentine blocks were inoculated: 16 with S...
  30. Seo J, Yeom J, Ko K. Actinomyces cardiffensis septicemia: a case report. Diagn Microbiol Infect Dis. 2012;73:86-8 pubmed publisher
    b>Actinomyces cardiffensis is an anaerobic, Gram-positive, non-spore-forming rod that was first identified by Hall et al. (Hall V. et al. (2002) J Clin Microbiol 40:3427-31)...
  31. Wu C, Mishra A, Reardon M, Huang I, Counts S, Das A, et al. Structural determinants of Actinomyces sortase SrtC2 required for membrane localization and assembly of type 2 fimbriae for interbacterial coaggregation and oral biofilm formation. J Bacteriol. 2012;194:2531-9 pubmed publisher
    As a pioneer colonizer of the oral cavity, Actinomyces oris expresses proteinaceous pili (also called fimbriae) to mediate the following two key events in biofilm formation: adherence to saliva deposits on enamel and interbacterial ..
  32. Do T, Henssge U, Gilbert S, Clark D, Beighton D. Evidence for recombination between a sialidase (nanH) of Actinomyces naeslundii and Actinomyces oris, previously named 'Actinomyces naeslundii genospecies 1 and 2'. FEMS Microbiol Lett. 2008;288:156-62 pubmed publisher
    b>Actinomyces spp., predominant members of human oral biofilms, may use extracellular sialidase to promote adhesion, deglycosylate immunoglobulins and liberation of nutrients...
  33. Sato T, Watanabe K, Kumada H, Toyama T, Tani Ishii N, Hamada N. Peptidoglycan of Actinomyces naeslundii induces inflammatory cytokine production and stimulates osteoclastogenesis in alveolar bone resorption. Arch Oral Biol. 2012;57:1522-8 pubmed publisher
    b>Actinomyces naeslundii, plays an important role in forming dental biofilms and causes gingival inflammation...
  34. Carrillo M, Valdez B, Vargas L, Alvarez L, Schorr M, Zlatev R, et al. In vitro Actinomyces israelii biofilm development on IUD copper surfaces. Contraception. 2010;81:261-4 pubmed publisher
    ..The predominant causative agent of human actinomycosis is Actinomyces israelii, which has been found on copper IUDs retrieved from patients.
  35. Reichenbach J, Lopatin U, Mahlaoui N, Beovic B, Siler U, Zbinden R, et al. Actinomyces in chronic granulomatous disease: an emerging and unanticipated pathogen. Clin Infect Dis. 2009;49:1703-10 pubmed publisher
    ..We report for the first time, to our knowledge, chronic infections with Actinomyces species in 10 patients with CGD...
  36. Wakabayashi K, Yano S, Kadowaki T, Tokushima T, Kanda H, Kobayashi K, et al. Pulmonary actinomycosis caused by Actinomyces cardiffensis. Intern Med. 2012;51:2929-31 pubmed
    We herein present the first case of pulmonary actinomycosis caused by Actinomyces cardiffensis (A. cardiffensis). A computed tomography (CT) examination revealed a nodule with cavitation in the left upper lobe of the lung...
  37. LeCorn D, Vertucci F, Rojas M, Progulske Fox A, Bélanger M. In vitro activity of amoxicillin, clindamycin, doxycycline, metronidazole, and moxifloxacin against oral Actinomyces. J Endod. 2007;33:557-60 pubmed
    b>Actinomyces spp have been increasingly associated with endodontic infections. However, the antimicrobial susceptibility of this genus has not been studied extensively...
  38. Lynch R, Ten Cate J. Effect of calcium glycerophosphate on demineralization in an in vitro biofilm model. Caries Res. 2006;40:142-7 pubmed
    ..In dentine, CaGP reduced demineralization significantly only when pulsed before the sucrose. The findings suggest that in vivo, the anti-caries potential of CaGP may be greater if it is applied before a cariogenic challenge...
  39. Yip H, Guo J, Wong W. Protection offered by root-surface restorative materials against biofilm challenge. J Dent Res. 2007;86:431-5 pubmed
    ..A biofilm of Streptococcus mutans, Streptococcus sobrinus, Lactobacillus rhamnosus, and Actinomyces naeslundii was co-cultured for 21 days on 24 glass-ionomer cement, resin-modified glass-ionomer cement, or ..
  40. Melgarejo Moreno P, Hellin Meseguer D, Marco Garrido A, Galindo Ortego X, Ruiz Macia J, Hostalet F. A correlation between age and Actinomyces in the adenotonsillar tissue of children. B-ENT. 2006;2:95-7 pubmed
    The purpose of this study was to investigate the presence of actinomyces in adenotonsillar disease, recurrent infections, or tonsillar hypertrophy in children...
  41. Jakubovics N, Gill S, Iobst S, Vickerman M, Kolenbrander P. Regulation of gene expression in a mixed-genus community: stabilized arginine biosynthesis in Streptococcus gordonii by coaggregation with Actinomyces naeslundii. J Bacteriol. 2008;190:3646-57 pubmed publisher
    Interactions involving genetically distinct bacteria, for example, between oral streptococci and actinomyces, are central to dental plaque development...
  42. Liu Y, Hu T, Jiang D, Zhang J, Zhou X. Regulation of urease gene of Actinomyces naeslundii in biofilms in response to environmental factors. FEMS Microbiol Lett. 2008;278:157-63 pubmed
    ..of oral bacteria has a profound influence on oral biofilm pH homeostasis and oral microbial ecology, and Actinomyces naeslundii is an important ureolytic organism in the oral cavity...
  43. Rickard A, Palmer R, Blehert D, Campagna S, Semmelhack M, Egland P, et al. Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth. Mol Microbiol. 2006;60:1446-56 pubmed
    ..We show that mutualistic and abundant biofilm growth in flowing saliva of two human oral commensal bacteria, Actinomyces naeslundii T14V and Streptococcus oralis 34, is dependent upon production of AI-2 by S. oralis 34...
  44. Koo H, Xiao J, Klein M, Jeon J. Exopolysaccharides produced by Streptococcus mutans glucosyltransferases modulate the establishment of microcolonies within multispecies biofilms. J Bacteriol. 2010;192:3024-32 pubmed publisher
    ..S. mutans grown with sucrose in the presence of Streptococcus oralis and Actinomyces naeslundii steadily formed exopolysaccharides, which allowed the initial clustering of bacterial cells and ..
  45. Jakubovics N, Gill S, Vickerman M, Kolenbrander P. Role of hydrogen peroxide in competition and cooperation between Streptococcus gordonii and Actinomyces naeslundii. FEMS Microbiol Ecol. 2008;66:637-44 pubmed publisher
    ..Streptococci do not produce catalase yet tolerate H(2)O(2). We recently demonstrated that coaggregation with Actinomyces naeslundii stabilizes arginine biosynthesis in S. gordonii...
  46. Lima E, Koo H, Vacca Smith A, Rosalen P, Del Bel Cury A. Adsorption of salivary and serum proteins, and bacterial adherence on titanium and zirconia ceramic surfaces. Clin Oral Implants Res. 2008;19:780-5 pubmed publisher
    ..In addition, the protein profiles and bacterial binding properties of pellicles on Ti and ZrO(2) were compared to those formed on hydroxyapatite (HA) surface...
  47. Paddick J, Brailsford S, Rao S, Soares R, Kidd E, Beighton D, et al. Effect of biofilm growth on expression of surface proteins of Actinomyces naeslundii genospecies 2. Appl Environ Microbiol. 2006;72:3774-9 pubmed
    The predominant surface proteins of biofilm and planktonic Actinomyces naeslundii, a primary colonizer of the tooth surface, were examined...
  48. Billington S, Post K, Jost B. Isolation of Arcanobacterium (Actinomyces) pyogenes from cases of feline otitis externa and canine cystitis. J Vet Diagn Invest. 2002;14:159-62 pubmed
    ..In both cases, the A. pyogenes isolates were presumptively identified by macrobiochemical tests, and then their identities were confirmed by polymerase chain reaction analysis and 16S rRNA gene sequencing...
  49. Tang G, Yip H, Samaranayake L, Chan K, Luo G, Fang H. Direct detection of cell surface interactive forces of sessile, fimbriated and non-fimbriated Actinomyces spp. using atomic force microscopy. Arch Oral Biol. 2004;49:727-38 pubmed
    b>Actinomyces species are predominant early colonizers of the oral cavity and prime mediators of inter-bacterial adhesion and coaggregation. Previous workers have evaluated the adhesion of Actinomyces spp...
  50. Palmer R, Kazmerzak K, Hansen M, Kolenbrander P. Mutualism versus independence: strategies of mixed-species oral biofilms in vitro using saliva as the sole nutrient source. Infect Immun. 2001;69:5794-804 pubmed
    ..coaggregating early colonizers of the tooth surface (Streptococcus gordonii DL1, Streptococcus oralis 34, and Actinomyces naeslundii T14V). Area coverage and cell cluster size measurements showed that attachment of A...
  51. Bonacho I, Pita S, Gómez Besteiro M. The importance of the removal of the intrauterine device in genital colonization by actinomyces. Gynecol Obstet Invest. 2001;52:119-23 pubmed
    ..with antibiotics, it is necessary to remove the intrauterine device (IUD) to eliminate genital colonization by Actinomyces. A randomized clinical trial was carried out. Patients were divided into two groups...
  52. Paddick J, Brailsford S, Kidd E, Gilbert S, Clark D, Alam S, et al. Effect of the environment on genotypic diversity of Actinomyces naeslundii and Streptococcus oralis in the oral biofilm. Appl Environ Microbiol. 2003;69:6475-80 pubmed
    The genotypic diversity of Actinomyces naeslundii genospecies 2 (424 isolates) and Streptococcus oralis (446 isolates) strains isolated from two sound approximal sites in all subjects who were either caries active (seven subjects) or ..
  53. Ton That H, Schneewind O. Assembly of pili in Gram-positive bacteria. Trends Microbiol. 2004;12:228-34 pubmed
  54. Figdor D, Davies J. Cell surface structures of Actinomyces israelii. Aust Dent J. 1997;42:125-8 pubmed
    b>Actinomyces israelii is the most common cause of human actinomycosis, a chronic granulomatous infection. Periapical actinomycosis involving A...
  55. Guggenheim M, Shapiro S, Gmür R, Guggenheim B. Spatial arrangements and associative behavior of species in an in vitro oral biofilm model. Appl Environ Microbiol. 2001;67:1343-50 pubmed
    The spatial arrangements and associative behavior of Actinomyces naeslundii, Veillonella dispar, Fusobacterium nucleatum, Streptococcus sobrinus, and Streptococcus oralis strains in an in vitro model of supragingival plaque were ..
  56. Hoflack L, Yeung M. Actinomyces naeslundii fimbrial protein Orf977 shows similarity to a streptococcal adhesin. Oral Microbiol Immunol. 2001;16:319-20 pubmed
    The nucleotide sequence of the chromosomal DNA, upstream of Actinomyces naeslundii T14V fimbrial gene fimA, was determined...
  57. Palmer R, Gordon S, Cisar J, Kolenbrander P. Coaggregation-mediated interactions of streptococci and actinomyces detected in initial human dental plaque. J Bacteriol. 2003;185:3400-9 pubmed
    Streptococci and actinomyces that initiate colonization of the tooth surface frequently coaggregate with each other as well as with other oral bacteria...
  58. Ramberg P, Sekino S, Uzel N, Socransky S, Lindhe J. Bacterial colonization during de novo plaque formation. J Clin Periodontol. 2003;30:990-5 pubmed
    ..To determine microbial changes that occur during plaque formation in a dentition free of gingival inflammation...
  59. Hall V, O Neill G, Magee J, Duerden B. Development of amplified 16S ribosomal DNA restriction analysis for identification of Actinomyces species and comparison with pyrolysis-mass spectrometry and conventional biochemical tests. J Clin Microbiol. 1999;37:2255-61 pubmed
    Identification of Actinomyces spp. by conventional phenotypic methods is notoriously difficult and unreliable...
  60. Collins M, Hoyles L, Kalfas S, Sundquist G, Monsen T, Nikolaitchouk N, et al. Characterization of Actinomyces isolates from infected root canals of teeth: description of Actinomyces radicidentis sp. nov. J Clin Microbiol. 2000;38:3399-403 pubmed
    Two strains of a previously undescribed Actinomyces-like bacterium were recovered in pure culture from infected root canals of teeth...
  61. Hall V, Talbot P, Stubbs S, Duerden B. Identification of clinical isolates of actinomyces species by amplified 16S ribosomal DNA restriction analysis. J Clin Microbiol. 2001;39:3555-62 pubmed
    ..ARDRA), using enzymes HaeIII and HpaII, was applied to 176 fresh and 299 stored clinical isolates of putative Actinomyces spp...
  62. Cisar J, Sandberg A, Reddy G, Abeygunawardana C, Bush C. Structural and antigenic types of cell wall polysaccharides from viridans group streptococci with receptors for oral actinomyces and streptococcal lectins. Infect Immun. 1997;65:5035-41 pubmed
    Lectin-mediated interactions between oral viridans group streptococci and actinomyces may play an important role in microbial colonization of the tooth surface...
  63. Busscher H, Rustema Abbing M, Bruinsma G, de Jager M, Gottenbos B, van der Mei H. Non-contact removal of coadhering and non-coadhering bacterial pairs from pellicle surfaces by sonic brushing and de novo adhesion. Eur J Oral Sci. 2003;111:459-64 pubmed
    ..This study compares removal and de novo adhesion of pairs of coadhering and non-coadhering oral actinomyces and streptococci by sonic brushing on salivary pellicles in a non-contact mode as a function of the distance ..
  64. Tang G, Samaranayake L, Yip H. Genotypic diversity of oral Actinomyces naeslundii genospecies 1 and 2 in caries-active preschool children. Oral Microbiol Immunol. 2004;19:371-8 pubmed
    A total of 991 isolates of Actinomyces naeslundii were obtained from sound approximal tooth sites in either caries-active (n = 35) or caries-free (n = 20) preschool children...
  65. Fukushima H, Yamamoto K, Hirohata K, Sagawa H, Leung K, Walker C. Localization and identification of root canal bacteria in clinically asymptomatic periapical pathosis. J Endod. 1990;16:534-8 pubmed
    ..The bacteria-positive cases of asymptomatic periapical pathosis have the potential to progress to symptomatic periapical pathosis...