actinobacteria

Summary

Summary: Class of BACTERIA with diverse morphological properties. Strains of Actinobacteria show greater than 80% 16S rDNA/rRNA sequence similarity among each other and also the presence of certain signature nucleotides. (Stackebrandt E. et al, Int. J. Syst. Bacteriol. (1997) 47:479-491)

Top Publications

  1. Lee L, Cheah Y, Mohd Sidik S, Ab Mutalib N, Tang Y, Lin H, et al. Molecular characterization of Antarctic actinobacteria and screening for antimicrobial metabolite production. World J Microbiol Biotechnol. 2012;28:2125-37 pubmed publisher
    The present study aimed to isolate actinobacteria from soil samples and characterized them using molecular tools and screened their secondary metabolites for antimicrobial activities...
  2. Lundberg D, Lebeis S, Paredes S, Yourstone S, Gehring J, Malfatti S, et al. Defining the core Arabidopsis thaliana root microbiome. Nature. 2012;488:86-90 pubmed publisher
    ..compartments from both soils feature overlapping, low-complexity communities that are markedly enriched in Actinobacteria and specific families from other phyla, notably Proteobacteria...
  3. Kaewkla O, Franco C. Rational approaches to improving the isolation of endophytic actinobacteria from Australian native trees. Microb Ecol. 2013;65:384-93 pubmed publisher
    ..16 weeks, excising colonies when they are visible and choosing Australian endemic trees as the source of the actinobacteria. A hierarchy of polyphasic methods based on culture morphology, amplified 16S rRNA gene restriction analysis ..
  4. Santiago G, Tency I, Verstraelen H, Verhelst R, Trog M, Temmerman M, et al. Longitudinal qPCR study of the dynamics of L. crispatus, L. iners, A. vaginae, (sialidase positive) G. vaginalis, and P. bivia in the vagina. PLoS ONE. 2012;7:e45281 pubmed publisher
    ..To obtain more detailed understanding of the causes of disturbance of the vaginal microflora (VMF), a longitudinal study was carried out for 17 women during two menstrual cycles...
  5. Caldera E, Currie C. The population structure of antibiotic-producing bacterial symbionts of Apterostigma dentigerum ants: impacts of coevolution and multipartite symbiosis. Am Nat. 2012;180:604-17 pubmed publisher
    ..which the ants cultivate for food, Ascomycetous fungal pathogens (Escovopsis), which parasitize cultivars, and Actinobacteria, which produce antibiotic compounds that suppress pathogen growth...
  6. Salem H, Kreutzer E, Sudakaran S, Kaltenpoth M. Actinobacteria as essential symbionts in firebugs and cotton stainers (Hemiptera, Pyrrhocoridae). Environ Microbiol. 2013;15:1956-68 pubmed publisher
    b>Actinobacteria engage in defensive symbioses with several insect taxa, but reports of nutritional contributions to their hosts have been exceptionally rare...
  7. Becerril Espinosa A, Freel K, Jensen P, Soria Mercado I. Marine Actinobacteria from the Gulf of California: diversity, abundance and secondary metabolite biosynthetic potential. Antonie Van Leeuwenhoek. 2013;103:809-19 pubmed publisher
    ..In this work we report the isolation and characterization of Actinobacteria from different sites in the western Gulf of California...
  8. Gupta R, Chen W, Adeolu M, Chai Y. Molecular signatures for the class Coriobacteriia and its different clades; proposal for division of the class Coriobacteriia into the emended order Coriobacteriales, containing the emended family Coriobacteriaceae and Atopobiaceae fam. nov., and Egg. Int J Syst Evol Microbiol. 2013;63:3379-97 pubmed publisher
    ..One additional CSI is uniquely present in all members of the class Coriobacteriia and the phylum Actinobacteria supporting their placement within this bacterial phylum...
  9. Kang I, Lee K, Yang S, Choi A, Kang D, Lee Y, et al. Genome sequence of "Candidatus Aquiluna" sp. strain IMCC13023, a marine member of the Actinobacteria isolated from an arctic fjord. J Bacteriol. 2012;194:3550-1 pubmed publisher
    ..quot; The genome information suggests that strain IMCC13023 is a photoheterotroph carrying actinorhodopsin, with the smallest genome ever reported for a free-living member of the Actinobacteria.

More Information

Publications105 found, 100 shown here

  1. Garcia S, McMahon K, Martinez Garcia M, Srivastava A, Sczyrba A, Stepanauskas R, et al. Metabolic potential of a single cell belonging to one of the most abundant lineages in freshwater bacterioplankton. ISME J. 2013;7:137-47 pubmed publisher
    b>Actinobacteria within the acI lineage are often numerically dominating in freshwater ecosystems, where they can account for >50% of total bacteria in the surface water. However, they remain uncultured to date...
  2. Li X, O Sullivan D. Contribution of the Actinobacteria to the growing diversity of lantibiotics. Biotechnol Lett. 2012;34:2133-45 pubmed publisher
    ..There is a growing number being identified from the Actinobacteria phylum and some of these exhibit novel modifications leading to an increased functional diversity among ..
  3. Santos C, Correia Neves M, Moradas Ferreira P, Mendes M. A walk into the LuxR regulators of Actinobacteria: phylogenomic distribution and functional diversity. PLoS ONE. 2012;7:e46758 pubmed publisher
    ..have been mainly focused on gram-negative organisms, and the presence of LuxR regulators in the gram-positive Actinobacteria phylum is still poorly explored...
  4. Strassert J, Köhler T, Wienemann T, Ikeda Ohtsubo W, Faivre N, Franckenberg S, et al. 'Candidatus Ancillula trichonymphae', a novel lineage of endosymbiotic Actinobacteria in termite gut flagellates of the genus Trichonympha. Environ Microbiol. 2012;14:3259-70 pubmed publisher
    ..genus Incisitermes (family Kalotermitidae) lacked 'Endomicrobia' and were associated with endosymbiotic Actinobacteria, which is highly unusual...
  5. Bortoluzzi A, Muskett F, Waters L, Addis P, Rieck B, Munder T, et al. Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors. J Biol Chem. 2013;288:14438-50 pubmed publisher
    ..RbpA could therefore influence the competition between principal and alternative sigma factors and hence the transcription profile of the cell...
  6. Zaremba Niedzwiedzka K, Andersson S. No ancient DNA damage in Actinobacteria from the Neanderthal bone. PLoS ONE. 2013;8:e62799 pubmed publisher
    ..Treatment with restriction enzymes prior to sequencing increased the relative proportion of mammalian DNA to 15%, but the large majority of sequences remain uncharacterized...
  7. Hoyles L, Clear J, McCartney A. Use of denaturing gradient gel electrophoresis to detect Actinobacteria associated with the human faecal microbiota. Anaerobe. 2013;22:90-6 pubmed publisher
    With the exceptions of the bifidobacteria, propionibacteria and coriobacteria, the Actinobacteria associated with the human gastrointestinal tract have received little attention...
  8. Anderson I, Abt B, Lykidis A, Klenk H, Kyrpides N, Ivanova N. Genomics of aerobic cellulose utilization systems in actinobacteria. PLoS ONE. 2012;7:e39331 pubmed publisher
    ..In contrast, aerobic actinobacteria utilize systems comprised of independently acting enzymes, often with carbohydrate binding domains...
  9. Subramani R, Aalbersberg W. Marine actinomycetes: an ongoing source of novel bioactive metabolites. Microbiol Res. 2012;167:571-80 pubmed publisher
  10. de Souza D, Lenoir A, Kasuya M, Ribeiro M, Devers S, Couceiro J, et al. Ectosymbionts and immunity in the leaf-cutting ant Acromyrmex subterraneus subterraneus. Brain Behav Immun. 2013;28:182-7 pubmed publisher
    ..Antibiotics produced by attine ectosymbionts (Actinobacteria) suppress the growth of Escovopsis spp., the specialized parasite of attine fungus gardens...
  11. Ghai R, Mizuno C, Picazo A, Camacho A, Rodriguez Valera F. Metagenomics uncovers a new group of low GC and ultra-small marine Actinobacteria. Sci Rep. 2013;3:2471 pubmed publisher
    We describe a deep-branching lineage of marine Actinobacteria with very low GC content (33%) and the smallest free living cells described yet (cell volume ca. 0...
  12. Ramon Garcia S, Ng C, Jensen P, Dosanjh M, Burian J, Morris R, et al. WhiB7, an Fe-S-dependent transcription factor that activates species-specific repertoires of drug resistance determinants in actinobacteria. J Biol Chem. 2013;288:34514-28 pubmed publisher
    ..Gene disruption experiments showed that three different Actinobacteria (Mycobacterium smegmatis, Streptomyces lividans, and Rhodococcus jostii) each exhibited a different whiB7-..
  13. McArthur K, Mitchell S, Tsueng G, Rheingold A, White D, Grodberg J, et al. Lynamicins A-E, chlorinated bisindole pyrrole antibiotics from a novel marine actinomycete. J Nat Prod. 2008;71:1732-7 pubmed publisher
    ..Significantly, compounds 1-5 were active against drug-resistant pathogens such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. ..
  14. Rokem J, Vongsangnak W, Nielsen J. Comparative metabolic capabilities for Micrococcus luteus NCTC 2665, the "Fleming" strain, and actinobacteria. Biotechnol Bioeng. 2011;108:2770-5 pubmed publisher
    Putative gene predictions of the Gram positive actinobacteria Micrococcus luteus (NCTC 2665, "Fleming strain") was used to construct a genome scale reconstruction of the metabolic network for this organism...
  15. Motohashi K, Irie K, Toda T, Matsuo Y, Kasai H, Sue M, et al. Studies on terpenoids produced by actinomycetes. 5-dimethylallylindole-3-carboxylic Acid and A80915G-8"-acid produced by marine-derived Streptomyces sp. MS239. J Antibiot (Tokyo). 2008;61:75-80 pubmed publisher
    ..MS239, two new terpenoids named 5-dimethylallylindole-3-carboxylic acid and A80915G-8''-acid were isolated and their structures were determined mainly by NMR analyses. ..
  16. Santos C, Vieira J, Tavares F, Benson D, Tisa L, Berry A, et al. On the nature of fur evolution: a phylogenetic approach in Actinobacteria. BMC Evol Biol. 2008;8:185 pubmed publisher
    ..On the other hand, members of the Actinobacteria comprise an ecologically diverse group of bacteria able to inhabit various natural environments, and for which ..
  17. Sharma A, Sommerfeld K, Bullerjahn G, Matteson A, Wilhelm S, Jezbera J, et al. Actinorhodopsin genes discovered in diverse freshwater habitats and among cultivated freshwater Actinobacteria. ISME J. 2009;3:726-37 pubmed publisher
    ..rhodopsin sequences named 'actinorhodopsins' (ActRs) was hypothesized to exist among uncultured planktonic Actinobacteria. ActRs were discovered by mining metagenomic data obtained during the Venter Institute's Global Ocean Sampling ..
  18. Libby E, Pascal K, Mordechai E, Adelson M, Trama J. Atopobium vaginae triggers an innate immune response in an in vitro model of bacterial vaginosis. Microbes Infect. 2008;10:439-46 pubmed publisher
    ..These results suggest that Atopobium vaginae stimulates an innate immune response from vaginal epithelial cells, leading to localized cytokine and defensin production, and possibly contributes to the pathogenesis of bacterial vaginosis. ..
  19. Chen Y, Ntai I, Ju K, Unger M, Zamdborg L, Robinson S, et al. A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria. J Proteome Res. 2012;11:85-94 pubmed publisher
    b>Actinobacteria such as streptomycetes are renowned for their ability to produce bioactive natural products including nonribosomal peptides (NRPs) and polyketides (PKs)...
  20. Olano C, Mendez C, Salas J. Antitumor compounds from marine actinomycetes. Mar Drugs. 2009;7:210-48 pubmed publisher
    ..Marine organisms have attracted special attention in the last years for their ability to produce interesting pharmacological lead compounds. ..
  21. te Poele E, Samborskyy M, Oliynyk M, Leadlay P, Bolhuis H, Dijkhuizen L. Actinomycete integrative and conjugative pMEA-like elements of Amycolatopsis and Saccharopolyspora decoded. Plasmid. 2008;59:202-16 pubmed publisher
    ..Several AICEs are able to mobilise chromosomal markers, suggesting that they play an important role in horizontal gene transfer and spread of antibiotic resistance, but also in evolution of genome plasticity...
  22. Eiler A, Heinrich F, Bertilsson S. Coherent dynamics and association networks among lake bacterioplankton taxa. ISME J. 2012;6:330-42 pubmed publisher
    ..Association networks with the abundant freshwater Actinobacteria and Proteobacteria in focus revealed complex interdependencies within bacterioplankton communities and ..
  23. Penn K, Jensen P. Comparative genomics reveals evidence of marine adaptation in Salinispora species. BMC Genomics. 2012;13:86 pubmed publisher
    b>Actinobacteria represent a consistent component of most marine bacterial communities yet little is known about the mechanisms by which these Gram-positive bacteria adapt to life in the marine environment...
  24. Das S, Ward L, Burke C. Prospects of using marine actinobacteria as probiotics in aquaculture. Appl Microbiol Biotechnol. 2008;81:419-29 pubmed publisher
    ..Marine actinobacteria were designated as the chemical factory a long time ago, and quite a large number of chemical substances have ..
  25. Babalola O, Kirby B, Le Roes Hill M, Cook A, Cary S, Burton S, et al. Phylogenetic analysis of actinobacterial populations associated with Antarctic Dry Valley mineral soils. Environ Microbiol. 2009;11:566-76 pubmed publisher
    ..conducted on mineral soil samples have revealed the presence of a wide diversity of microorganisms, with actinobacteria representing one of the largest phylotypic groups...
  26. Seviour R, Kragelund C, Kong Y, Eales K, Nielsen J, Nielsen P. Ecophysiology of the Actinobacteria in activated sludge systems. Antonie Van Leeuwenhoek. 2008;94:21-33 pubmed publisher
    This review considers what is known about the Actinobacteria in activated sludge systems, their abundance and their functional roles there...
  27. Xie G, Chain P, Lo C, Liu K, Gans J, Merritt J, et al. Community and gene composition of a human dental plaque microbiota obtained by metagenomic sequencing. Mol Oral Microbiol. 2010;25:391-405 pubmed publisher
    ..Furthermore, ~2.8% of the total predicted genes coded for proteins involved in resistance to antibiotics and toxic compounds, suggesting that the oral cavity is an important reservoir for antimicrobial resistance...
  28. Fowler Goldsworthy K, Gust B, Mouz S, Chandra G, Findlay K, Chater K. The actinobacteria-specific gene wblA controls major developmental transitions in Streptomyces coelicolor A3(2). Microbiology. 2011;157:1312-28 pubmed publisher
    ..A3(2) sporulation gene whiB is the paradigm of a family of genes (wbl, whiB-like) that are confined to actinobacteria. The chromosome of S...
  29. Liebner S, Harder J, Wagner D. Bacterial diversity and community structure in polygonal tundra soils from Samoylov Island, Lena Delta, Siberia. Int Microbiol. 2008;11:195-202 pubmed
    ..taxonomical units (OTUs) and cells visualized by fluorescence in-situ hybridization, Bacteroidetes and Actinobacteria were the dominant members of the bacterial community in all sites...
  30. Hahn M. Description of seven candidate species affiliated with the phylum Actinobacteria, representing planktonic freshwater bacteria. Int J Syst Evol Microbiol. 2009;59:112-7 pubmed publisher
    b>Actinobacteria comprise a substantial fraction of the bacterioplankton in freshwater lakes and streams. Numerous cultivation-independent investigations have retrieved actinobacterial 16S rRNA gene sequences from such habitats...
  31. Eustáquio A, O Hagan D, Moore B. Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide. J Nat Prod. 2010;73:378-82 pubmed publisher
    ..As a proof of principle, we report here the induced production of fluorosalinosporamide by replacing the chlorinase gene salL from Salinispora tropica with the fluorinase gene flA. ..
  32. Lemke M, Lienau E, Rothe J, Pagioro T, Rosenfeld J, DeSalle R. Description of freshwater bacterial assemblages from the upper paraná river floodpulse system, Brazil. Microb Ecol. 2009;57:94-103 pubmed publisher
    ..from Patos Lagoon was least like other samples in that it had no Firmicutes present and was dominated by Actinobacteria. Verrucomicrobia OTUs were only found in the free-living assemblage...
  33. Poulsen M, Oh D, Clardy J, Currie C. Chemical analyses of wasp-associated streptomyces bacteria reveal a prolific potential for natural products discovery. PLoS ONE. 2011;6:e16763 pubmed publisher
    ..We performed enrichment isolations from 33 wasps and obtained more than 200 isolates of Streptomyces Actinobacteria. Chemical analyses of 15 of these isolates identified 11 distinct and structurally diverse secondary ..
  34. Schneider K, Keller S, Wolter F, Röglin L, Beil W, Seitz O, et al. Proximicins A, B, and C-antitumor furan analogues of netropsin from the marine actinomycete Verrucosispora induce upregulation of p53 and the cyclin kinase inhibitor p21. Angew Chem Int Ed Engl. 2008;47:3258-61 pubmed publisher
  35. Fiedler H, Bruntner C, Riedlinger J, Bull A, Knutsen G, Goodfellow M, et al. Proximicin A, B and C, novel aminofuran antibiotic and anticancer compounds isolated from marine strains of the actinomycete Verrucosispora. J Antibiot (Tokyo). 2008;61:158-63 pubmed publisher
    ..Proximicins show a weak antibacterial activity but a strong cytostatic effect to various human tumor cell lines. ..
  36. Menard J, Fenollar F, Henry M, Bretelle F, Raoult D. Molecular quantification of Gardnerella vaginalis and Atopobium vaginae loads to predict bacterial vaginosis. Clin Infect Dis. 2008;47:33-43 pubmed publisher
    ..Bacterial vaginosis (BV) is a poorly detected public health problem that is associated with preterm delivery and for which no reliable diagnostic tool exists...
  37. Olano C, Mendez C, Salas J. Antitumor compounds from actinomycetes: from gene clusters to new derivatives by combinatorial biosynthesis. Nat Prod Rep. 2009;26:628-60 pubmed publisher
  38. Kaltenpoth M. Actinobacteria as mutualists: general healthcare for insects?. Trends Microbiol. 2009;17:529-35 pubmed publisher
    ..In particular, different actinobacteria have been found to defend ants, beetles and wasps against detrimental microorganisms by producing antibiotics...
  39. Gontang E, Gaudêncio S, Fenical W, Jensen P. Sequence-based analysis of secondary-metabolite biosynthesis in marine actinobacteria. Appl Environ Microbiol. 2010;76:2487-99 pubmed publisher
    A diverse collection of 60 marine-sediment-derived Actinobacteria representing 52 operational taxonomic units was screened by PCR for genes associated with secondary-metabolite biosynthesis...
  40. De Backer E, Verhelst R, Verstraelen H, Alqumber M, Burton J, Tagg J, et al. Quantitative determination by real-time PCR of four vaginal Lactobacillus species, Gardnerella vaginalis and Atopobium vaginae indicates an inverse relationship between L. gasseri and L. iners. BMC Microbiol. 2007;7:115 pubmed
    ..iners and L. jensenii to obtain a quantitative non culture-based determination of these species in 71 vaginal samples from 32 pregnant and 28 non-pregnant women aged between 18 and 45 years...
  41. Baltz R. Renaissance in antibacterial discovery from actinomycetes. Curr Opin Pharmacol. 2008;8:557-63 pubmed publisher
  42. Anzai K, Nakashima T, Kuwahara N, Suzuki R, Ohfuku Y, Takeshita S, et al. Actinomycete bacteria isolated from the sediments at coastal and offshore area of Nagasaki Prefecture, Japan: diversity and biological activity. J Biosci Bioeng. 2008;106:215-7 pubmed publisher
    ..The isolates were compared with taxa and biological activities of their secondary metabolites. It is suggested that a variety of actinomycetes are isolated from different marine environments. ..
  43. Alam M, Medema M, Takano E, Breitling R. Comparative genome-scale metabolic modeling of actinomycetes: the topology of essential core metabolism. FEBS Lett. 2011;585:2389-94 pubmed publisher
    ..As has been reported for low-degree metabolites in several organisms, low-degree enzymes (in linear pathways) turn out to be generally more essential than high-degree enzymes (in metabolic hubs). ..
  44. Martinez Garcia M, Swan B, Poulton N, Gomez M, Masland D, Sieracki M, et al. High-throughput single-cell sequencing identifies photoheterotrophs and chemoautotrophs in freshwater bacterioplankton. ISME J. 2012;6:113-23 pubmed publisher
    ..Our data demonstrate that Actinobacteria, including clusters acI, Luna and acSTL, are the predominant freshwater RBs...
  45. Barona Gomez F, Cruz Morales P, Noda García L. What can genome-scale metabolic network reconstructions do for prokaryotic systematics?. Antonie Van Leeuwenhoek. 2012;101:35-43 pubmed publisher
    ..Through selected examples from the Actinobacteria, which have been inferred from GSMRs and experimentally confirmed after phenotypic characterisation, it will ..
  46. Choi I, Shin H, Lee H, Kwon H. Streptochlorin, a marine natural product, inhibits NF-kappaB activation and suppresses angiogenesis in vitro. J Microbiol Biotechnol. 2007;17:1338-43 pubmed
    ..These data demonstrate that streptochlorin is a new inhibitor of NF-kappaB activation and can be a basis for the development of novel anti-angiogenic agents. ..
  47. den Hengst C, Buttner M. Redox control in actinobacteria. Biochim Biophys Acta. 2008;1780:1201-16 pubmed publisher
    As most actinobacteria are obligate aerobes, they have to cope with endogenously generated reactive oxygen species, and actinobacterial pathogens have to resist oxidative attack by phagocytes...
  48. Salas J, Mendez C. Indolocarbazole antitumour compounds by combinatorial biosynthesis. Curr Opin Chem Biol. 2009;13:152-60 pubmed publisher
    ..Combinatorial biosynthesis is therefore providing a new approach for increasing structural diversity in this family of natural products. ..
  49. Nithyanand P, Thenmozhi R, Rathna J, Pandian S. Inhibition of Streptococcus pyogenes biofilm formation by coral-associated actinomycetes. Curr Microbiol. 2010;60:454-60 pubmed publisher
    ..pyogenes) of three M types and thus may inhibit biofilm formation. CAA represent an interesting source of marine invertebrates-derived antibiofilm agents in the development of new strategies to combat Streptococcal biofilms. ..
  50. Zhi X, Li W, Stackebrandt E. An update of the structure and 16S rRNA gene sequence-based definition of higher ranks of the class Actinobacteria, with the proposal of two new suborders and four new families and emended descriptions of the existing higher taxa. Int J Syst Evol Microbiol. 2009;59:589-608 pubmed publisher
    The higher ranks of the class Actinobacteria were proposed and described in 1997...
  51. Penn K, JENKINS C, Nett M, Udwary D, Gontang E, McGlinchey R, et al. Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria. ISME J. 2009;3:1193-203 pubmed publisher
    ..A comparative analysis of the complete genome sequences of the marine Actinobacteria Salinispora tropica and Salinispora arenicola reveals that 75% of the species-specific genes are located in 21 ..
  52. Peraud O, Biggs J, Hughen R, Light A, Concepcion G, Olivera B, et al. Microhabitats within venomous cone snails contain diverse actinobacteria. Appl Environ Microbiol. 2009;75:6820-6 pubmed publisher
    ..This suggests that cone snails may represent an underexplored reservoir of novel actinomycetes of potential interest for drug discovery. ..
  53. Kanasi E, Dewhirst F, Chalmers N, Kent R, Moore A, Hughes C, et al. Clonal analysis of the microbiota of severe early childhood caries. Caries Res. 2010;44:485-97 pubmed publisher
    ..Severe early childhood caries is a microbial infection that severely compromises the dentition of young children. The aim of this study was to characterize the microbiota of severe early childhood caries...
  54. Ghai R, Rodriguez Valera F, McMahon K, Toyama D, Rinke R, Cristina Souza de Oliveira T, et al. Metagenomics of the water column in the pristine upper course of the Amazon river. PLoS ONE. 2011;6:e23785 pubmed publisher
    ..Among the microbial taxa found, the cosmopolitan freshwater acI lineage of the actinobacteria was clearly dominant...
  55. Hodges T, Slattery M, Olson J. Unique actinomycetes from marine caves and coral reef sediments provide novel PKS and NRPS biosynthetic gene clusters. Mar Biotechnol (NY). 2012;14:270-80 pubmed publisher
  56. Traag B, van Wezel G. The SsgA-like proteins in actinomycetes: small proteins up to a big task. Antonie Van Leeuwenhoek. 2008;94:85-97 pubmed publisher
    ..Here we review 10 years of research on the SsgA-like proteins in actinomycetes and discuss the most interesting regulatory, functional, phylogenetic and applied aspects of this relatively unknown protein family...
  57. Scott J, Oh D, Yuceer M, Klepzig K, Clardy J, Currie C. Bacterial protection of beetle-fungus mutualism. Science. 2008;322:63 pubmed publisher
  58. Krogius Kurikka L, Kassinen A, Paulin L, Corander J, Mäkivuokko H, Tuimala J, et al. Sequence analysis of percent G+C fraction libraries of human faecal bacterial DNA reveals a high number of Actinobacteria. BMC Microbiol. 2009;9:68 pubmed publisher
  59. Tan H, Deng Z, Cao L. Isolation and characterization of actinomycetes from healthy goat faeces. Lett Appl Microbiol. 2009;49:248-53 pubmed publisher
    ..To isolate and characterize actinomycetes with probiotic activities from healthy goat faeces...
  60. Zeder M, Peter S, Shabarova T, Pernthaler J. A small population of planktonic Flavobacteria with disproportionally high growth during the spring phytoplankton bloom in a prealpine lake. Environ Microbiol. 2009;11:2676-86 pubmed publisher
    ..An initial peak in the proportions of BrdU-positive Actinobacteria (30%) preceded a distinct rise of their cell numbers during the period of the Chl a maximum...
  61. Nett M, Ikeda H, Moore B. Genomic basis for natural product biosynthetic diversity in the actinomycetes. Nat Prod Rep. 2009;26:1362-84 pubmed publisher
  62. Veselá A, Franc M, Pelantová H, Kubac D, Vejvoda V, Sulc M, et al. Hydrolysis of benzonitrile herbicides by soil actinobacteria and metabolite toxicity. Biodegradation. 2010;21:761-70 pubmed publisher
    The soil actinobacteria Rhodococcus rhodochrous PA-34, Rhodococcus sp. NDB 1165 and Nocardia globerula NHB-2 grown in the presence of isobutyronitrile exhibited nitrilase activities towards benzonitrile (approx. 1.1-1...
  63. Hong K, Gao A, Xie Q, Gao H, Zhuang L, Lin H, et al. Actinomycetes for marine drug discovery isolated from mangrove soils and plants in China. Mar Drugs. 2009;7:24-44 pubmed publisher
    ..We conclude that actinomycetes isolated from mangrove habitats are a potentially rich source for the discovery of anti-infection and anti-tumor compounds, and of agents for treating neurodegenerative diseases and diabetes...
  64. Venancio T, Aravind L. Reconstructing prokaryotic transcriptional regulatory networks: lessons from actinobacteria. J Biol. 2009;8:29 pubmed publisher
    ..Recent studies, including one in BMC Systems Biology, address this problem in the relatively underexplored actinobacteria clade, which includes major pathogenic and economically relevant taxa.
  65. Sandoval Calderón M, Geiger O, Guan Z, Barona Gomez F, Sohlenkamp C. A eukaryote-like cardiolipin synthase is present in Streptomyces coelicolor and in most actinobacteria. J Biol Chem. 2009;284:17383-90 pubmed publisher
    ..The broad occurrence of putative orthologues of Sco1389 among the actinobacteria suggests that CL synthesis involving a eukaryotic type Cls is common in actinobacteria.
  66. Würdemann D, Tindall B, Pukall R, Lünsdorf H, Strompl C, Namuth T, et al. Gordonibacter pamelaeae gen. nov., sp. nov., a new member of the Coriobacteriaceae isolated from a patient with Crohn's disease, and reclassification of Eggerthella hongkongensis Lau et al. 2006 as Paraeggerthella hongkongensis gen. nov., comb. nov. Int J Syst Evol Microbiol. 2009;59:1405-15 pubmed publisher
    ..2006 be transferred to a new genus as Paraeggerthella hongkongensis gen. nov., comb. nov.; the type strain of Paraeggerthella hongkongensis is HKU10(T) (=DSM 16106(T) =CCUG 49250(T))...
  67. Clavel T, Charrier C, Braune A, Wenning M, Blaut M, Haller D. Isolation of bacteria from the ileal mucosa of TNFdeltaARE mice and description of Enterorhabdus mucosicola gen. nov., sp. nov. Int J Syst Evol Microbiol. 2009;59:1805-12 pubmed publisher
    ..nov., sp. nov., to accommodate strain Mt1B8(T). The type strain of Enterorhabdus mucosicola is Mt1B8(T) (=DSM 19490(T) =CCUG 54980(T))...
  68. Sen R, Ishak H, Estrada D, Dowd S, Hong E, Mueller U. Generalized antifungal activity and 454-screening of Pseudonocardia and Amycolatopsis bacteria in nests of fungus-growing ants. Proc Natl Acad Sci U S A. 2009;106:17805-10 pubmed publisher
    ..If association with Pseudonocardia is adaptive to attine ants, alternate roles of such microbes could include the protection of ants or sanitation of the nest...
  69. SCHAFER J, Jäckel U, Kampfer P. Development of a new PCR primer system for selective amplification of Actinobacteria. FEMS Microbiol Lett. 2010;311:103-12 pubmed publisher
    The occurrence of Actinobacteria in water-damaged building materials as well as the clinical relevance of some Actinobacteria (e.g. Saccharopolyspora spp., Mycobacterium spp., Nocardia spp., etc...
  70. Bai S, Huang L, Su J, Tian Y, Zheng T. Algicidal effects of a novel marine actinomycete on the toxic dinoflagellate Alexandrium tamarense. Curr Microbiol. 2011;62:1774-81 pubmed publisher
    ..This is the first report of an actinomycete algicide to the toxic dinoflagellate A. tamarense. Our results indicate that BS01 could be a potential bio-agent for controlling harmful algal blooms...
  71. Oh D, Gontang E, Kauffman C, Jensen P, Fenical W. Salinipyrones and pacificanones, mixed-precursor polyketides from the marine actinomycete Salinispora pacifica. J Nat Prod. 2008;71:570-5 pubmed publisher
    ..This relationship was shown to be a consequence of the geometric isomerization of one double bond. The phenomenon of polyketide module skipping is proposed to explain the unusual biosynthesis of the salinipyrones and the pacificanones...
  72. Tarao M, Jezbera J, Hahn M. Involvement of cell surface structures in size-independent grazing resistance of freshwater Actinobacteria. Appl Environ Microbiol. 2009;75:4720-6 pubmed publisher
    ..strain DS on ultramicrobacterial Actinobacteria affiliated with the Luna-2 cluster and ultramicrobacterial Betaproteobacteria of the species Polynucleobacter ..
  73. Zucchi T, Guidolin A, Consoli F. Isolation and characterization of actinobacteria ectosymbionts from Acromyrmex subterraneus brunneus (Hymenoptera, Formicidae). Microbiol Res. 2011;166:68-76 pubmed publisher
    ..search for Pseudonocardia associated with several attine species, but few studies have indicated that other actinobacteria may be associated with these ants as well...
  74. Olano C, Mendez C, Salas J. Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis. Nat Prod Rep. 2010;27:571-616 pubmed
  75. Sharma A, Zhaxybayeva O, Papke R, Doolittle W. Actinorhodopsins: proteorhodopsin-like gene sequences found predominantly in non-marine environments. Environ Microbiol. 2008;10:1039-56 pubmed publisher
    ..Phylogenomic analyses of genes adjacent to those encoding these novel rhodopsins suggest affiliation to the Actinobacteria, and hence we propose to name these divergent, non-marine rhodopsins 'actinorhodopsins'...
  76. Abdulla H. Bioweathering and biotransformation of granitic rock minerals by actinomycetes. Microb Ecol. 2009;58:753-61 pubmed publisher
  77. Philosof A, Sabehi G, Beja O. Comparative analyses of actinobacterial genomic fragments from Lake Kinneret. Environ Microbiol. 2009;11:3189-200 pubmed publisher
    The high genomic G+C group of Actinobacteria possesses a variety of physiological and metabolic properties, and exhibits diverse lifestyles and ecological distribution...
  78. Khan S, Izumikawa M, Motohashi K, Mukai A, Takagi M, Shin ya K. Distribution of the 3-hydroxyl-3-methylglutaryl coenzyme A reductase gene and isoprenoid production in marine-derived Actinobacteria. FEMS Microbiol Lett. 2010;304:89-96 pubmed publisher
    During the course of our screening program to isolate isoprenoids from marine Actinobacteria, 523 actinobacterial strains were isolated from 18 marine sponges, a tunicate, and two marine sediments...
  79. Adekambi T, Butler R, Hanrahan F, Delcher A, Drancourt M, Shinnick T. Core gene set as the basis of multilocus sequence analysis of the subclass Actinobacteridae. PLoS ONE. 2011;6:e14792 pubmed publisher
    ..The subclass Actinobacteridae comprised about 85% of the actinobacteria families...
  80. Eckert E, Salcher M, Posch T, Eugster B, Pernthaler J. Rapid successions affect microbial N-acetyl-glucosamine uptake patterns during a lacustrine spring phytoplankton bloom. Environ Microbiol. 2012;14:794-806 pubmed publisher
    ..with Fluviicola and from Betaproteobacteria (BET) of the Limnohabitans cluster to more grazing resistant AcI Actinobacteria (ACT) and to filamentous morphotypes. This was paralleled by successive blooms of viruses and HNF...
  81. Ghai R, Pasic L, Fernández A, Martin Cuadrado A, Mizuno C, McMahon K, et al. New abundant microbial groups in aquatic hypersaline environments. Sci Rep. 2011;1:135 pubmed publisher
    ..We describe for the first time, a group of low GC Actinobacteria, related to freshwater Actinobacteria, abundant in low and intermediate salinities...
  82. te Poele E, Bolhuis H, Dijkhuizen L. Actinomycete integrative and conjugative elements. Antonie Van Leeuwenhoek. 2008;94:127-43 pubmed publisher
  83. Haferburg G, Groth I, Möllmann U, Kothe E, Sattler I. Arousing sleeping genes: shifts in secondary metabolism of metal tolerant actinobacteria under conditions of heavy metal stress. Biometals. 2009;22:225-34 pubmed publisher
    ..Most actinobacteria are soil-borne microbes with a remarkable capability for the synthesis of a broad variety of biologically ..
  84. Newton G, Buchmeier N, Fahey R. Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria. Microbiol Mol Biol Rev. 2008;72:471-94 pubmed publisher
    Mycothiol (MSH; AcCys-GlcN-Ins) is the major thiol found in Actinobacteria and has many of the functions of glutathione, which is the dominant thiol in other bacteria and eukaryotes but is absent in Actinobacteria...
  85. Suihko M, Priha O, Alakomi H, Thompson P, Mälarstig B, Stott R, et al. Detection and molecular characterization of filamentous actinobacteria and thermoactinomycetes present in water-damaged building materials. Indoor Air. 2009;19:268-77 pubmed publisher
    In this study the dominant filamentous actinobacteria occurring in water-damaged building materials were detected by culture and characterized by automated ribotyping and 16S rRNA gene sequencing...
  86. Baltz R. Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters. J Ind Microbiol Biotechnol. 2010;37:759-72 pubmed publisher
  87. Shivaji S, Kumari K, Kishore K, Pindi P, Rao P, Radha Srinivas T, et al. Vertical distribution of bacteria in a lake sediment from Antarctica by culture-independent and culture-dependent approaches. Res Microbiol. 2011;162:191-203 pubmed publisher
    ..T-RFLP and 16S rRNA clone libraries was similar and clones were affiliated with Proteobacteria, Bacteroidetes, Actinobacteria and Firmicutes...
  88. Ouyang Y, Wu H, Xie L, Wang G, Dai S, Chen M, et al. A method to type the potential angucycline producers in actinomycetes isolated from marine sponges. Antonie Van Leeuwenhoek. 2011;99:807-15 pubmed publisher
    ..The specific primer set targeting the cyclase can be used to identify putative angucycline producers among marine actinobacteria, and aid in the discovery of novel angucyclines.
  89. Donovan C, Sieger B, Kramer R, Bramkamp M. A synthetic Escherichia coli system identifies a conserved origin tethering factor in Actinobacteria. Mol Microbiol. 2012;84:105-16 pubmed publisher
    ..Although speculated, polar chromosome tethering factors have not been identified for Actinobacteria, to date...
  90. Servin J, Herbold C, Skophammer R, Lake J. Evidence excluding the root of the tree of life from the actinobacteria. Mol Biol Evol. 2008;25:1-4 pubmed
    The Actinobacteria are found in aquatic and terrestrial habitats throughout the world and are among the most morphologically varied prokaryotes...
  91. Dubeau M, Ghinet M, Jacques P, Clermont N, Beaulieu C, Brzezinski R. Cytosine deaminase as a negative selection marker for gene disruption and replacement in the genus Streptomyces and other actinobacteria. Appl Environ Microbiol. 2009;75:1211-4 pubmed publisher
    We developed a novel negative selection system for actinobacteria based on cytosine deaminase (CodA)...
  92. Kaltenpoth M, Winter S, Kleinhammer A. Localization and transmission route of Coriobacterium glomerans, the endosymbiont of pyrrhocorid bugs. FEMS Microbiol Ecol. 2009;69:373-83 pubmed publisher
    ..of the 16S rRNA gene, closely related bacterial symbionts were detected in the cotton stainer bug Dysdercus fasciatus (Hemiptera: Pyrrhocoridae), suggesting that the symbiosis with Actinobacteria may be widespread among pyrrhocorid bugs.