fusobacterium necrophorum

Summary

Summary: A species of gram-negative, non-spore-forming bacteria isolated from the natural cavities of man and other animals and from necrotic lesions, abscesses, and blood.

Top Publications

  1. Chirinos J, Lichtstein D, Garcia J, Tamariz L. The evolution of Lemierre syndrome: report of 2 cases and review of the literature. Medicine (Baltimore). 2002;81:458-65 pubmed
    ..A high degree of clinical suspicion is necessary for diagnosis. Fusobacterium necrophorum is the usual etiologic agent. The disease progresses in several steps...
  2. Kuppalli K, Livorsi D, Talati N, Osborn M. Lemierre's syndrome due to Fusobacterium necrophorum. Lancet Infect Dis. 2012;12:808-15 pubmed publisher
    We present a case of a patient with Lemierre's syndrome caused by Fusobacterium necrophorum who developed a right frontal lobe brain abscess...
  3. Ehlers Klug T, Rusan M, Fuursted K, Ovesen T. Fusobacterium necrophorum: most prevalent pathogen in peritonsillar abscess in Denmark. Clin Infect Dis. 2009;49:1467-72 pubmed publisher
    ..majority of PTA aspirates also contain strains of anaerobes, and accumulating evidence indicates that Fusobacterium necrophorum (FN) could be involved in acute tonsillitis...
  4. Klug T, Henriksen J, Fuursted K, Ovesen T. Similar recovery rates of Fusobacterium necrophorum from recurrently infected and non-infected tonsils. Dan Med Bull. 2011;58:A4295 pubmed
    Recent studies implicate the presence of Fusobacterium necrophorum (FN) in recurrent tonsillitis (RT), acute tonsillitis and peritonsillar abscess...
  5. Holm K, Frick I, Bjorck L, Rasmussen M. Activation of the contact system at the surface of Fusobacterium necrophorum represents a possible virulence mechanism in Lemièrre's syndrome. Infect Immun. 2011;79:3284-90 pubmed publisher
    b>Fusobacterium necrophorum causes Lemièrre's syndrome, a serious disease with septic thrombophlebitis of the internal jugular vein, pulmonary involvement, and systemic inflammation...
  6. Bennett G, Hickford J, Sedcole R, Zhou H. Dichelobacter nodosus, Fusobacterium necrophorum and the epidemiology of footrot. Anaerobe. 2009;15:173-6 pubmed publisher
    ..nodosus) or Fusobacterium necrophorum (F. necrophorum) species were present on each swab...
  7. Aliyu S, Marriott R, Curran M, Parmar S, Bentley N, Brown N, et al. Real-time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice. J Med Microbiol. 2004;53:1029-35 pubmed
    b>Fusobacterium necrophorum is recognized as the cause of a severe life-threatening illness characterized by bacteraemia with metastatic abscesses following an acute sore throat (Lemierre's disease). However, the importance of F...
  8. Ramirez S, Hild T, Rudolph C, Sty J, Kehl S, Havens P, et al. Increased diagnosis of Lemierre syndrome and other Fusobacterium necrophorum infections at a Children's Hospital. Pediatrics. 2003;112:e380 pubmed
    To assess the apparent increase in the diagnosis of Lemierre syndrome (LS) and other Fusobacterium necrophorum infections at a large children's hospital...
  9. Ianniello F, Ferri E, Pinzani A. [Septic thrombophlebitis of the internal jugular vein due to Fusobacterium necrophorum (Lemierre's syndrome): case report and review of literature]. Acta Otorhinolaryngol Ital. 1998;18:332-7 pubmed
    ..It is usually due to Fusobacterium necrophorum. Although Lemierre's syndrome is rare, it is potentially fatal...

More Information

Publications87

  1. Riordan T. Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome. Clin Microbiol Rev. 2007;20:622-59 pubmed
    Human infection with Fusobacterium necrophorum usually involves F. necrophorum subsp. funduliforme rather than F. necrophorum subsp. necrophorum, which is a common pathogen in animals...
  2. Amess J, O NEILL W, Giollariabhaigh C, Dytrych J. A six-month audit of the isolation of Fusobacterium necrophorum from patients with sore throat in a district general hospital. Br J Biomed Sci. 2007;64:63-5 pubmed
    b>Fusobacterium necrophorum is an obligate anaerobe believed to be a member of the normal flora of the human oropharangeal and urogenital tract...
  3. Batty A, Wren M, Gal M. Fusobacterium necrophorum as the cause of recurrent sore throat: comparison of isolates from persistent sore throat syndrome and Lemierre's disease. J Infect. 2005;51:299-306 pubmed
    b>Fusobacterium necrophorum is a well established cause of Lemierre's disease (LD); a syndrome characterised by severe sore throat, septicaemia, multiple abscesses and jugular vein thrombosis...
  4. Jaremko J, Kirton A, Brenner J. A 12-year-old girl with pharyngitis, meningitis and sinovenous thrombosis. CMAJ. 2003;169:811-2 pubmed
  5. Brazier J, Hall V, Yusuf E, Duerden B. Fusobacterium necrophorum infections in England and Wales 1990-2000. J Med Microbiol. 2002;51:269-72 pubmed
    In response to a marked increase in both the number of Fusobacterium necrophorum bacteraemia reports to the PHLS Communicable Disease Surveillance Centre and the number of F...
  6. Moe K, Yano T, Misumi K, Kubota C, Nibe K, Yamazaki W, et al. Detection of antibodies against Fusobacterium necrophorum and Porphyromonas levii-like species in dairy cattle with papillomatous digital dermatitis. Microbiol Immunol. 2010;54:338-46 pubmed publisher
    ..Moreover, 16S rRNA genes of Fusobacterium necrophorum and Porphyromonas levii-like species were detected in the lesions...
  7. Batty A, Wren M. Prevalence of Fusobacterium necrophorum and other upper respiratory tract pathogens isolated from throat swabs. Br J Biomed Sci. 2005;62:66-70 pubmed
    b>Fusobacterium necrophorum, an anaerobic, Gram-negative rod, has been identified recently as a significant cause of persistent sore throat syndrome (PSTS)...
  8. Redford M, Ellis R, Rees C. Fusobacterium necrophorum infection associated with portal vein thrombosis. J Med Microbiol. 2005;54:993-5 pubmed
    ..upper respiratory tract or gastrointestinal infection who developed portal vein thrombosis secondary to Fusobacterium necrophorum septicaemia. The patient responded well to systemic antibiotic therapy. The implications of F...
  9. Kuduvalli P, Jukka C, Stallwood M, Battersby C, Neal T, Masterson G, et al. Fusobacterium necrophorum-induced sepsis: an unusual case of Lemierre's syndrome. Acta Anaesthesiol Scand. 2005;49:572-5 pubmed
    ..The causative organisms are the anaerobic fusobacteria, most commonly Fusobacterium necrophorum. We describe the evaluation, therapeutic interventions and management of a patient with Lemierre's ..
  10. Chand D, Brady R, Bissler J. Hemolytic uremic syndrome in an adolescent with Fusobacterium necrophorum bacteremia. Am J Kidney Dis. 2001;37:E22 pubmed
    ..We present the first reported case of Fusobacterium necrophorum bacteremia that presented initially with atypical HUS...
  11. Friberg N, Carlson P, Kentala E, Mattila P, Kuusela P, Meri S, et al. Factor H binding as a complement evasion mechanism for an anaerobic pathogen, Fusobacterium necrophorum. J Immunol. 2008;181:8624-32 pubmed
    b>Fusobacterium necrophorum subspecies funduliforme is an obligate anaerobic Gram-negative rod causing invasive infections such as the life-threatening Lemierre's syndrome (sore throat, septicemia, jugular vein thrombosis, and disseminated ..
  12. Jacinto R, Montagner F, Signoretti F, Almeida G, Gomes B. Frequency, microbial interactions, and antimicrobial susceptibility of Fusobacterium nucleatum and Fusobacterium necrophorum isolated from primary endodontic infections. J Endod. 2008;34:1451-6 pubmed publisher
    This study assessed the prevalence and microbial interactions of Fusobacterium nucleatum and Fusobacterium necrophorum in primary endodontic infections from a Brazilian population and their antimicrobial susceptibility to some ..
  13. Zhou H, Bennett G, Hickford J. Variation in Fusobacterium necrophorum strains present on the hooves of footrot infected sheep, goats and cattle. Vet Microbiol. 2009;135:363-7 pubmed publisher
    ..nodosus) and Fusobacterium necrophorum (F. necrophorum) are thought to be involved in the etiology of this disease...
  14. Giridharan W, De S, Osman E, Amma L, Hughes J, McCormick M. Complicated otitis media caused by Fusobacterium necrophorum. J Laryngol Otol. 2004;118:50-3 pubmed
    b>Fusobacterium necrophorum is implicated as an aetiological agent in a variety of necrotic diseases, such as Lemièrre's syndrome (LS) in humans...
  15. Jensen A, Hagelskjaer Kristensen L, Prag J. Detection of Fusobacterium necrophorum subsp. funduliforme in tonsillitis in young adults by real-time PCR. Clin Microbiol Infect. 2007;13:695-701 pubmed
    ..with non-streptococcal tonsillitis (NST) and 92 healthy controls were examined for the presence of Fusobacterium necrophorum DNA using a novel TaqMan-based real-time quantitative PCR assay for F. necrophorum subspecies...
  16. Bank S, Nielsen H, Mathiasen B, Leth D, Kristensen L, Prag J. Fusobacterium necrophorum- detection and identification on a selective agar. APMIS. 2010;118:994-9 pubmed publisher
    Within the last decade, Fusobacterium necrophorum subsp. funduliforme has been considered a clinically important pathogen causing pharyngitis especially in adolescents and young adults. F...
  17. Guo D, Sun D, Wu R, Yang H, Zheng J, Fan C, et al. An indirect ELISA for serodiagnosis of cattle footrot caused by Fusobacterium necrophorum. Anaerobe. 2010;16:317-20 pubmed publisher
    A serodiagnostic ELISA (rL-ELISA) using recombinant truncated leukotoxin protein PL2 (aa 311-644) of Fusobacterium necrophorum as antigen was developed for detection of antibodies against F. necrophorum from cattle footrot...
  18. Tadepalli S, Stewart G, Nagaraja T, Narayanan S. Human Fusobacterium necrophorum strains have a leukotoxin gene and exhibit leukotoxic activity. J Med Microbiol. 2008;57:225-31 pubmed publisher
    b>Fusobacterium necrophorum, a Gram-negative anaerobe, causes a variety of necrotic infections in humans and animals. There are two subspecies: subsp. necrophorum and subsp. funduliforme. In cattle, subsp...
  19. Narayanan S, Stewart G, Chengappa M, Willard L, Shuman W, Wilkerson M, et al. Fusobacterium necrophorum leukotoxin induces activation and apoptosis of bovine leukocytes. Infect Immun. 2002;70:4609-20 pubmed
    b>Fusobacterium necrophorum, a gram-negative, rod-shaped, anaerobic bacterium, is a primary or secondary etiological agent in a variety of necrotic, purulent infections in humans and animals...
  20. Hagelskjaer Kristensen L, Prag J. Lemierre's syndrome and other disseminated Fusobacterium necrophorum infections in Denmark: a prospective epidemiological and clinical survey. Eur J Clin Microbiol Infect Dis. 2008;27:779-89 pubmed publisher
    In a 3-year prospective study, all cases of disseminated Fusobacterium necrophorum infections found in Denmark from 1998 to 2001 were analysed, with the aim of describing the epidemiology and clinical features of the variants of Lemierre'..
  21. Jankowich M, El Sameed Y, Abu Hijleh M. A 21-year-old man with fever and sore throat rapidly progressive to hemoptysis and respiratory failure. Diagnosis: Lemierre syndrome with Fusobacterium necrophorum sepsis. Chest. 2007;132:1706-9 pubmed
  22. Schmid T, Miskin H, Schlesinger Y, Argaman Z, Kleid D. Respiratory failure and hypercoagulability in a toddler with Lemierre's syndrome. Pediatrics. 2005;115:e620-2 pubmed
    ..Blood cultures were positive for Fusobacterium necrophorum. Screening for hypercoagulability revealed 2 known risk factors: a mutation in the prothrombin gene and ..
  23. Citron D. Update on the taxonomy and clinical aspects of the genus fusobacterium. Clin Infect Dis. 2002;35:S22-7 pubmed
    ..Two subspecies have been described for Fusobacterium necrophorum, and a new species, Fusobacterium equinum, which is related to F...
  24. Nazifi S, Esmailnezhad Z, Haghkhah M, Ghadirian S, Mirzaei A. Acute phase response in lame cattle with interdigital dermatitis. World J Microbiol Biotechnol. 2012;28:1791-6 pubmed publisher
    ..None of the colonies on enriched blood agar was identified as Fusobacterium necrophorum. Four (26...
  25. Narayanan S, Chengappa M, Stewart G, Nagaraja T. Immunogenicity and protective effects of truncated recombinant leukotoxin proteins of Fusobacterium necrophorum in mice. Vet Microbiol. 2003;93:335-47 pubmed
    b>Fusobacterium necrophorum, a gram-negative, anaerobic and rod-shaped bacterium, is generally an opportunistic pathogen and causes a wide variety of necrotic infections in animals and humans...
  26. Brazier J. Human infections with Fusobacterium necrophorum. Anaerobe. 2006;12:165-72 pubmed
    b>Fusobacterium necrophorum is a Gram-negative anaerobic bacillus that can be a primary pathogen causing either localised abscesses and throat infections or systemic life-threatening disease. Systemic infections due to F...
  27. Bicalho M, Machado V, Oikonomou G, Gilbert R, Bicalho R. Association between virulence factors of Escherichia coli, Fusobacterium necrophorum, and Arcanobacterium pyogenes and uterine diseases of dairy cows. Vet Microbiol. 2012;157:125-31 pubmed publisher
    ..pyogenes specific; fimH (a type 1 pilus component), Escherichia coli specific; and lktA (leukotoxin), Fusobacterium necrophorum specific. Uterine swabs were collected from 111 postpartum dairy cows...
  28. Ravn T, Huniche B, Breum L, Jørgen Christensen J. Lemierre's syndrome: still an important clinical entity. Scand J Infect Dis. 2006;38:299-301 pubmed
    We report a case of Lemierre's syndrome caused by Fusobacterium necrophorum and discuss characteristics of this potentially fatal condition which, though rare, may have a rising frequency...
  29. Bank S, Jensen A, Nielsen H, Kristensen L, Voldstedlund M, Prag J. Fusobacterium necrophorum findings in Denmark from 2010 to 2014 using data from the Danish microbiology database. APMIS. 2016;124:1087-1092 pubmed publisher
    b>Fusobacterium necrophorum findings in Denmark and estimation of the incidence of F. necrophorum bacteraemia was described using data from the nationwide Danish microbiology database (MiBa)...
  30. Klug T. Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess. Dan Med J. 2017;64: pubmed
    ..that FN was recovered from PTA patients with increasing frequency and that patients infected with Fusobacterium necrophorum (FN) seemed to be more severely affected than patients infected with other bacteria...
  31. Checkley S, Janzen E, Campbell J, McKinnon J. Efficacy of vaccination against Fusobacterium necrophorum infection for control of liver abscesses and footrot in feedlot cattle in western Canada. Can Vet J. 2005;46:1002-7 pubmed
    A randomized and blinded field trial was carried out to evaluate the efficacy of a Fusobacterium necrophorum bacterin for control of liver abscesses and footrot under commercial feedlot conditions in western Canada...
  32. Shibahara T, Akiba T, Maeda T, Ogata T, Honda R, Ishikawa Y, et al. Immunohistochemical and ultrastructural identification of Fusobacterium necrophorum subsp. necrophorum in bovine fatal necrotizing glossitis. J Vet Med Sci. 2002;64:523-6 pubmed
    ..Immunohistochemically, Fusobacterium necrophorum subsp...
  33. Braunbeck A, Geiger E, Weber R, Maier M, Daecke W, Fiebig C, et al. [Phlegmon of the palm of the hand as initial manifestation of the Lemierre syndrome]. Unfallchirurg. 2010;113:155-8 pubmed publisher
    ..In this case, positron emission tomography (PET) was revealed to be an appropriate instrument to determine the extent of the disease in a one step procedure. ..
  34. Holm K, Bank S, Nielsen H, Kristensen L, Prag J, Jensen A. The role of Fusobacterium necrophorum in pharyngotonsillitis - A review. Anaerobe. 2016;42:89-97 pubmed publisher
    b>Fusobacterium necrophorum is a gram-negative anaerobic bacterium that is the causative agent of the invasive disease Lemierre's syndrome...
  35. Karkos P, Asrani S, Karkos C, Leong S, Theochari E, Alexopoulou T, et al. Lemierre's syndrome: A systematic review. Laryngoscope. 2009;119:1552-9 pubmed publisher
    ..radiological evidence of internal jugular vein thrombosis, and isolation of anaerobic pathogens, mainly Fusobacterium necrophorum. It was once called the forgotten disease because of its rarity, but it may not be that uncommon after ..
  36. Takazono T, Izumikawa K, Tsurutani J, Tanaka A, Kakugawa T, Fukuda Y, et al. Lemierre's syndrome followed by acute respiratory distress syndrome successfully rescued by antibiotics and hemoperfusion with polymyxin B-immobilized fiber. Jpn J Infect Dis. 2009;62:133-6 pubmed
    ..Isolation of Fusobacterium necrophorum from the blood culture and the contrast-enhanced scan revealed thrombosis and thrombophlebitis in the ..
  37. Farooq S, Wani S, Hassan M, Aalamgeer S, Kashoo Z, Magray S, et al. The detection and prevalence of leukotoxin gene variant strains of Fusobacterium necrophorum in footrot lesions of sheep in Kashmir, India. Anaerobe. 2018;51:36-41 pubmed publisher
    ..study was to determine the prevalence and identification of leukotoxin gene, lktA, variant strains of Fusobacterium necrophorum in the footrot lesions of sheep. The detection of F...
  38. Agerholm J, Boye M, Aalbaek B. Ovine fetal necrobacillosis. J Comp Pathol. 2007;136:213-21 pubmed
    The association of Fusobacterium necrophorum with late term abortion in sheep is reported...
  39. Ehrenfried Berthelsen R, Hein L. [Lemierre's syndrome following peritonsillar abscess]. Ugeskr Laeger. 2012;174:1534-5 pubmed
    Lemierre's syndrome is a rare but serious condition, characterized by disseminated infection with Fusobacterium necrophorum, most often originating from the oropharynx...
  40. Van T, Cox L, COX M, Dien Bard J. Prevalence of Fusobacterium necrophorum in Children Presenting with Pharyngitis. J Clin Microbiol. 2017;55:1147-1153 pubmed publisher
    i>Fusobacterium necrophorum, an obligate anaerobic bacterium, was recently reported to be an important cause of bacterial pharyngitis with a prevalence as high as that of group A Streptococcus (GAS) in adolescents and young ..
  41. Olson J, Mandava N. Bilateral intraocular involvement in Lemierre's syndrome. Br J Ophthalmol. 2006;90:249-50 pubmed
  42. Darling M, Bryant S, Kunz A, Weisse M. Necrobacillosis: A case report of complicated Fusobacterium necrophorum septicemia. Anaerobe. 2010;16:171-3 pubmed publisher
    Necrobacillosis due to Fusobacterium necrophorum is an uncommon anaerobic infection. It has a wide range of presentations and commonly presents as Lemierre's syndrome. We present a case of necrobacillosis defined by F...
  43. Baills M, Freydiere A, Floret D. [Septic osteomyelitis of the hip after Fusobacterium necrophorum pharyngitis]. Med Mal Infect. 2010;40:544-7 pubmed publisher
    ..The bone and joint biopsy samples were sterile but the presence of the Fusobacterium necrophorum was demonstrated by PCR...
  44. Samant J, Peacock J. Fusobacterium necrophorum endocarditis Case report and review of the literature. Diagn Microbiol Infect Dis. 2011;69:192-5 pubmed publisher
    b>Fusobacterium necrophorum is a gram-negative anaerobic bacillus that can cause serious systemic infections typically in previously healthy young adults...
  45. Degaffe G, Murphy J, Butler I, Shelburne J, Heresi G. Severe narrowing of left cavernous carotid artery associated with Fusobacterium necrophorum infection. Anaerobe. 2013;22:118-20 pubmed publisher
    ..We report a case of Lemierre's disease in a 12 year old boy with severe narrowing of the left cavernous carotid artery. ..
  46. Hodgson R, Emig M, Pisarello J. Hyperbaric oxygen (HBO2) in the treatment of Lemierre syndrome. Undersea Hyperb Med. 2003;30:87-91 pubmed
    ..Subsequent to invasion and thrombophlebitis of the internal jugular vein, Fusobacterium necrophorum septicemia occurs, with rigors, high fever, and septic thromboembolism to peripheral sites, especially ..
  47. Jariwala R, Srialluri S, Huang M, Boppana S. Methicillin-resistant Staphylococcus aureus as a Cause of Lemierre's Syndrome. Pediatr Infect Dis J. 2017;36:429-431 pubmed publisher
    ..The organisms most often responsible are Fusobacterium necrophorum or anaerobic flora...
  48. DiLorenzo N, Dahlen C, Diez Gonzalez F, Lamb G, Larson J, DiCostanzo A. Effects of feeding polyclonal antibody preparations on rumen fermentation patterns, performance, and carcass characteristics of feedlot steers. J Anim Sci. 2008;86:3023-32 pubmed publisher
    In a previous study, preparations of polyclonal antibodies (PAP) against Fusobacterium necrophorum (PAP-Fn) or Streptococcus bovis (PAP-Sb) were successful in decreasing ruminal counts of target bacteria and increasing ruminal pH in ..
  49. Boye M, Aalbaek B, Agerholm J. Fusobacterium necrophorum determined as abortifacient in sheep by laser capture microdissection and fluorescence in situ hybridization. Mol Cell Probes. 2006;20:330-6 pubmed
    ..The present work describes the identification of Fusobacterium necrophorum in formalin-fixed tissue samples from three sets of ovine twins aborted at late pregnancy by a technique ..
  50. Hayashi M, Yamawaki I, Nakata J, Watanabe N, Ohkawa S. [A case of Lemierre syndrome]. Nihon Kokyuki Gakkai Zasshi. 2003;41:651-4 pubmed
    ..Although Lemierre syndrome is a relatively uncommon disease with the potentially life-threatening complication of acute pharyngotonsillitis, this syndrome should be considered in cases of severe tonsillitis or pharyngitis...
  51. Handler M, Miriovsky B, Gendelman H, Sandkovsky U. Fusobacterium necrophorum causing infective endocarditis and liver and splenic abscesses. Rev Inst Med Trop Sao Paulo. 2011;53:169-72 pubmed
    A 25-year-old male without prior co-morbidities was admitted to hospital with Fusobacterium necrophorum bacteremia, where he was found to have liver and splenic abscesses...
  52. Cruz C, Pescador C, Nakajima Y, Driemeier D. Immunopathological investigations on bovine digital epidermitis. Vet Rec. 2005;157:834-40 pubmed
    ..sections stained positively with polyclonal antisera to Treponema pallidum, Campylobacter jejuni and Fusobacterium necrophorum, respectively...
  53. de Sousa E, Ferraz C, Gomes B, Pinheiro E, Teixeira F, de Souza Filho F. Bacteriological study of root canals associated with periapical abscesses. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;96:332-9 pubmed
    ..canals with periapical abscesses and to ascertain the susceptibility of Peptostreptococcus prevotii and Fusobacterium necrophorum to antimicrobials...
  54. Iwasaki T, Yamamoto T, Inoue K, Takaku K. A case of Lemierre's syndrome in association with liver abscess without any other metastatic lesions. Intern Med. 2012;51:1419-23 pubmed
    ..LS is commonly caused by Fusobacterium necrophorum. Herein, we present a case of LS with liver abscesses that presented as a sole metastatic lesion...
  55. Wright W, Shiner C, Ribes J. Lemierre syndrome. South Med J. 2012;105:283-8 pubmed publisher
    ..an uncommon complication of pharyngitis in the United States and caused most commonly by the bacterium Fusobacterium necrophorum. The syndrome is characterized by a history of recent pharyngitis followed by ipsilateral internal ..
  56. Agarwal R, Arunachalam P, Bosman D. Lemierre's syndrome: a complication of acute oropharyngitis. J Laryngol Otol. 2000;114:545-7 pubmed
    ..In this case report the patient presented with acute sore throat that led to a bacteraemia with internal jugular vein thrombosis and subsequent cranial nerve palsies...
  57. Huynh Moynot S, Commandeur D, Danguy Des Deserts M, Drouillard I, Leguen P, Ould Ahmed M. [Septic shock Fusobacterium necrophorum from origin gynecological at complicated an acute respiratory distress syndrome: a variant of Lemierre's syndrome]. Ann Biol Clin (Paris). 2011;69:202-7 pubmed publisher
    ..The microbiological blood test allows to put in evidence Fusobacterium necrophorum found in a blood culture and is sensitive to the amoxicilline-acide clavulanique and metronidazole...
  58. Bennett G, van Loenen A, Zhou H, Sedcole R, Hickford J. The detection of Dichelobacter nodosus and Fusobacterium necrophorum from footrot lesions in New Zealand goats. Anaerobe. 2009;15:177 pubmed publisher
  59. Trapp C, Tamai J, Schleiss M. Septic arthritis secondary to fusobacterium necrophorum in a 4-year-old girl: case report and review of the literature. Pediatr Infect Dis J. 2005;24:846-7 pubmed
    We report an unusual case of septic arthritis in a 4-year-old child caused by Fusobacterium necrophorum. In spite of aggressive parenteral antibiotic therapy with ampicillin-sulbactam after surgical drainage, disease recurred, requiring ..
  60. Thomas N, Brook I. Animal bite-associated infections: microbiology and treatment. Expert Rev Anti Infect Ther. 2011;9:215-26 pubmed publisher
    ..Here, we discuss the common animal bite associated infections, and provide the most up to date information regarding their management...
  61. Crum Cianflone N, Mayer R. An unusual case of Lemierre's syndrome presenting as pyomyositis. Am J Med Sci. 2008;335:499-501 pubmed publisher
    ..We present such a case involving a 17-year-old male patient with pyomyositis and fasciitis due to necrobacillosis. Fusobacterium spp. should be considered in the differential diagnosis of cases involving sepsis syndrome and pyomyositis...
  62. Bentham J, Pollard A, Milford C, Anslow P, Pike M. Cerebral infarct and meningitis secondary to Lemierre's syndrome. Pediatr Neurol. 2004;30:281-3 pubmed
    The case is reported of a young man with Fusobacterium necrophorum septicemia who developed cavernous sinus thrombosis, meningitis, carotid artery stenosis and stroke...
  63. Jane R, Johnson P. Critical care nurses be aware: Lemierre's syndrome is on the rise. Aust Crit Care. 2003;16:126-32 pubmed
    ..A case study of a young woman is presented to illustrate the complexity of the condition, and highlight how early diagnosis and prompt initiation of appropriate intravenous antibiotic therapy ensured a favourable clinical outcome...
  64. Veldhoen E, Wolfs T, van Vught A. Two cases of fatal meningitis due to Fusobacterium necrophorum. Pediatr Neurol. 2007;36:261-3 pubmed
    It is extremely important to consider Fusobacterium necrophorum as a cause of meningitis in children after otitis or other upper respiratory tract infections, because of its increasing incidence...
  65. Ma M, Jauch E, Johnson M. A case of Lemierre's syndrome. Eur J Emerg Med. 2003;10:139-42 pubmed
    ..Its incidence appears to be increasing. We present a case of Lemierre's syndrome, most notable for the patient's essentially benign physical examination and lack of clinical improvement with penicillin...
  66. Solla Hach E, Salgado Ordóñez F, Díaz Morant V, Lara Fernández A, Ruiz Cantero A, Hita Pérez J. [Abdominal pain and necrobacillosis]. An Med Interna. 2002;19:545-6 pubmed
  67. Litmathe J, Zardo P, Dickgreber N, May G, Sucker C, Fischer S. Severe ARDS induced by fusobacterial infections: a rare clinical presentation of Lemierre syndrome. Thorac Cardiovasc Surg. 2013;61:754-7 pubmed publisher
    ..We report two cases of young female patients afflicted by Lemierre syndrome with additional severe ARDS and present an overview of the current literature. ..
  68. Sonsale P, Philipson M, Bowskill J. Septic arthritis of the knee due to Fusobacterium necrophorum. J Clin Microbiol. 2004;42:3369-70 pubmed
    ..We report the isolation of Fusobacterium necrophorum from joint aspirate in a case of acute septic arthritis, which presented 3 weeks after the drainage of a ..
  69. O Brien W, Lattin G, Thompson A. Lemierre syndrome: an all-but-forgotten disease. AJR Am J Roentgenol. 2006;187:W324 pubmed
  70. Fleskens A, Scheltinga M, van Eerten P, Verhoef L, Pasmans H, Vreugdenhil G. [Sore throat and a swollen neck: Lemierre's syndrome until proven otherwise]. Ned Tijdschr Geneeskd. 2006;150:2461-6 pubmed
    ..Spread of organisms may lead to sepsis and organ failure. The main pathogen is Fusobacterium necrophorum. Early recognition is essential, since prompt antibiotic treatment is usually effective...
  71. Cester C, Beguin J, Toutain P. The use of an experimental metritis model to study antibiotic distribution in genital tract secretions in the ewe. Vet Res. 1996;27:479-89 pubmed
    ..priming by inoculation in the uterine lumen of a bacterial suspension of Actinomyces pyogenes and Fusobacterium necrophorum Ewes were given a single iv administration of spiramycin at a dose of 20 mg.kg-1...
  72. Chamseddin K, Kirkwood M. Lemierre's Syndrome Associated Mycotic Aneurysm of the External Carotid Artery with Primary Internal Carotid Artery Occlusion in a Previously Healthy 18-Year-Old Female. Ann Vasc Surg. 2016;36:291.e11-291.e14 pubmed publisher
    ..The patient was managed with open ligation of the ECA with essentially complete recovery. ..
  73. Judd O, Medcalf M, Malik T. Case 2: An unusual presentation of an unusual condition (discussion and diagnosis). Acta Paediatr. 2008;97:828-9 pubmed publisher
  74. Rosique López L, Rodríguez Domínguez F, Navarro Paule P, Soler Valcárcel A. [Lemierre's syndrome. An unusual variant]. Acta Otorrinolaringol Esp. 2007;58:217-8 pubmed
    ..In most cases the syndrome is caused by Fusobacterium necrophorum. This disease usually occurs in young healthy individuals with an oropharyngeal infection, implying high ..
  75. Ergas D, Abdul Hai A, Sthoeger Z, Menahem B, Miller R. Multiple pyogenic liver abscesses following hemorrhoid banding. Isr Med Assoc J. 2007;9:753-4 pubmed
  76. Okamoto K, Kanoe M, Watanabe T. Collagenolytic activity of a cell wall preparation from Fusobacterium necrophorum subsp. necrophorum. Microbios. 2001;106 Suppl 2:89-95 pubmed
    A collagenolytic preparation of Fusobacterium necrophorum subsp. necrophorum was derived from the bacterial cell. It was further treated for gel permeation with Toyopearl HW 50, followed by Sepharose 4B column chromatography...
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