micromonospora

Summary

Summary: A genus of gram-positive bacteria that forms a branched mycelium. It commonly occurs as a saprophytic form in soil and aquatic environments.

Top Publications

  1. Wang H, Yeo S, Xu J, Xu X, He H, Ronca F, et al. Isolation of streptonigrin and its novel derivative from Micromonospora as inducing agents of p53-dependent cell apoptosis. J Nat Prod. 2002;65:721-4 pubmed
    ..novel natural derivative 7-(1-methyl-2-oxopropyl)streptonigrin (2) were isolated from an actinomycete strain, Micromonospora sp. IM 2670...
  2. Li D, Li H, Ni X, Zhang H, Xia H. Construction of a gentamicin C1a-overproducing strain of Micromonospora purpurea by inactivation of the gacD gene. Microbiol Res. 2013;168:263-7 pubmed publisher
    ..To obtain a gentamicin C1a-overproducing strain, we inactivated gacD gene in Micromonospora purpurea...
  3. Sousa T, Jimenez P, Ferreira E, Silveira E, Braz Filho R, Pessoa O, et al. Anthracyclinones from Micromonospora sp. J Nat Prod. 2012;75:489-93 pubmed publisher
    ..4), were isolated from a strain of Micromonospora sp. associated with the tunicate Eudistoma vannamei...
  4. Anzai Y, Saito N, Tanaka M, Kinoshita K, Koyama Y, Kato F. Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida. FEMS Microbiol Lett. 2003;218:135-41 pubmed
    ..desosamine and mycinose, at the C-5 and C-21 positions, is a 16-membered macrolide antibiotic produced by Micromonospora griseorubida A11725, which shows strong antimicrobial activity against Gram-positive bacteria...
  5. Gutierrez Lugo M, Woldemichael G, Singh M, Suarez P, Maiese W, Montenegro G, et al. Isolation of three new naturally occurring compounds from the culture of Micromonospora sp. P1068. Nat Prod Res. 2005;19:645-52 pubmed
    Bioassay guided isolation of an antibacterial extract prepared from the fermentation broth of a Micromonospora sp...
  6. Chan J, Lu A, Bennet A. Turnover is rate-limited by deglycosylation for Micromonospora viridifaciens sialidase-catalyzed hydrolyses: conformational implications for the Michaelis complex. J Am Chem Soc. 2011;133:2989-97 pubmed publisher
  7. Rusnak K, Troyanovich J, Mierzwa R, Chu M, Patel M, Weinstein M. An antibiotic with activity against gram-positive bacteria from the gentamicin-producing strain of Micromonospora purpurea. Appl Microbiol Biotechnol. 2001;56:502-3 pubmed
    A mixture of polycyclic aromatic compounds with activity against gram-positive bacteria was isolated from a gentamicin-producing species of Micromonospora.
  8. Himabindu M, Jetty A. Optimization of nutritional requirements for gentamicin production by Micromonospora echinospora. Indian J Exp Biol. 2006;44:842-8 pubmed
    ..inoculum levels and age were determined on gentamicin production and biomass dry weight production for Micromonospora echinospora, a gentamicin producing strain...
  9. Igarashi Y, Miyanaga S, Onaka H, Takeshita M, Furumai T. Revision of the structure assigned to the antibiotic BU-4664L from Micromonopora. J Antibiot (Tokyo). 2005;58:350-2 pubmed
    The structure assigned to the antitumor antibiotic BU-4664L from Micromonospora sp...

More Information

Publications73

  1. Kharel M, Basnet D, Lee H, Liou K, Moon Y, Kim J, et al. Molecular cloning and characterization of a 2-deoxystreptamine biosynthetic gene cluster in gentamicin-producing Micromonospora echinospora ATCC15835. Mol Cells. 2004;18:71-8 pubmed
    The organization of the 2-deoxystreptamine (DOS) biosynthetic gene cluster of Micromonospora echinospora has been determined. Sequencing of a 14...
  2. Carro L, Sproer C, Alonso P, Trujillo M. Diversity of Micromonospora strains isolated from nitrogen fixing nodules and rhizosphere of Pisum sativum analyzed by multilocus sequence analysis. Syst Appl Microbiol. 2012;35:73-80 pubmed publisher
    It was recently reported that Micromonospora inhabits the intracellular tissues of nitrogen fixing nodules of the wild legume Lupinus angustifolius...
  3. Hoskisson P, England R, Sharples G, Hobbs G. Modulation of glycogen and trehalose levels in Micromonospora echinospora (ATCC 15837). Antonie Van Leeuwenhoek. 2004;86:225-33 pubmed
    The growth of Micromonospora echinospora was studied in high and low C/N ratio medium using both batch and continuous culture. Asparagine was consumed rapidly in batch cultures where it served as both a nitrogen and carbon source...
  4. Thawai C, Tanasupawat S, Kudo T. Micromonospora pattaloongensis sp. nov., isolated from a Thai mangrove forest. Int J Syst Evol Microbiol. 2008;58:1516-21 pubmed publisher
    ..The data from these analyses indicated that the novel strain should be classified as a member of the genus Micromonospora and that the closest relative was Micromonospora olivasterospora DSM 43868(T) (98...
  5. Carro L, Pujic P, Trujillo M, Normand P. Micromonospora is a normal occupant of actinorhizal nodules. J Biosci. 2013;38:685-93 pubmed
    ..Many of these contaminants, which were later found to be Micromonospora, were obtained from Casuarina and Coriaria...
  6. Igarashi Y, Yanase S, Sugimoto K, Enomoto M, Miyanaga S, Trujillo M, et al. Lupinacidin C, an inhibitor of tumor cell invasion from Micromonospora lupini. J Nat Prod. 2011;74:862-5 pubmed publisher
    A new anthraquinone derivative, lupinacidin C (1), was isolated from the endophytic actinomycete Micromonospora lupini...
  7. Laakso J, Mocek U, Van Dun J, Wouters W, Janicot M. R176502, a new bafilolide metabolite with potent antiproliferative activity from a novel Micromonospora species. J Antibiot (Tokyo). 2003;56:909-16 pubmed
    ..R176502 (1) was isolated from the liquid fermentation cultures of a novel Micromonospora species found in African river bottom sediment...
  8. Abdelmohsen U, Szesny M, Othman E, Schirmeister T, Grond S, Stopper H, et al. Antioxidant and anti-protease activities of diazepinomicin from the sponge-associated Micromonospora strain RV115. Mar Drugs. 2012;10:2208-21 pubmed publisher
    ..Diazepinomicin was isolated from the marine sponge-associated strain Micromonospora sp. RV115 and was identified by spectroscopic analysis and by comparison to literature data...
  9. Maravic Vlahovicek G, Cubrilo S, Tkaczuk K, Bujnicki J. Modeling and experimental analyses reveal a two-domain structure and amino acids important for the activity of aminoglycoside resistance methyltransferase Sgm. Biochim Biophys Acta. 2008;1784:582-90 pubmed publisher
  10. Carro L, Pukall R, Sproer C, Kroppenstedt R, Trujillo M. Micromonospora cremea sp. nov. and Micromonospora zamorensis sp. nov., isolated from the rhizosphere of Pisum sativum. Int J Syst Evol Microbiol. 2012;62:2971-7 pubmed publisher
    ..Phylogenetic, chemotaxonomic and morphological analyses confirmed that the three strains belonged to the genus Micromonospora. 16S rRNA gene sequence analysis of strains CR30(T) and CR36 showed a close relationship to Micromonospora ..
  11. Zhao H, Kassama Y, Young M, Kell D, Goodacre R. Differentiation of Micromonospora isolates from a coastal sediment in Wales on the basis of Fourier transform infrared spectroscopy, 16S rRNA sequence analysis, and the amplified fragment length polymorphism technique. Appl Environ Microbiol. 2004;70:6619-27 pubmed
    ..Most of them were putatively assigned to the genera Streptomyces and Micromonospora on the basis of their morphological characteristics, and there appeared to be no difference whether the ..
  12. Igarashi Y, Trujillo M, Martínez Molina E, Yanase S, Miyanaga S, Obata T, et al. Antitumor anthraquinones from an endophytic actinomycete Micromonospora lupini sp. nov. Bioorg Med Chem Lett. 2007;17:3702-5 pubmed
    ..and B (2), have been isolated from the culture broth of a new endophytic actinomycete belonging to the genus Micromonospora. Lupinacidins were found to show significant inhibitory effects on the invasion of murine colon 26-L5 ..
  13. Xie Q, Qu Z, Lin H, Li L, Hong K. Micromonospora haikouensis sp. nov., isolated from mangrove soil. Antonie Van Leeuwenhoek. 2012;101:649-55 pubmed publisher
    ..Phylogenetic analysis of the 16S rRNA gene sequence of strain 232617(T) indicated the highest similarity with Micromonospora siamensis TT2-4(T) (99.05%), Micromonospora krabiensis A-2(T) (98...
  14. Watson J, Newstead S, Dookhun V, Taylor G, Bennet A. Contribution of the active site aspartic acid to catalysis in the bacterial neuraminidase from Micromonospora viridifaciens. FEBS Lett. 2004;577:265-9 pubmed
    A recombinant D92G mutant sialidase from Micromonospora viridifaciens has been cloned, expressed and purified...
  15. Charan R, Schlingmann G, Janso J, Bernan V, Feng X, Carter G. Diazepinomicin, a new antimicrobial alkaloid from a marine Micromonospora sp. J Nat Prod. 2004;67:1431-3 pubmed
    ..dibenzodiazepine alkaloid, diazepinomicin (1), isolated from the culture of a marine actinomycete of the genus Micromonospora was characterized using spectroscopic methods...
  16. Alonso Vega P, Normand P, Bacigalupe R, Pujic P, Lajus A, Vallenet D, et al. Genome sequence of Micromonospora lupini Lupac 08, isolated from root nodules of Lupinus angustifolius. J Bacteriol. 2012;194:4135 pubmed publisher
    b>Micromonospora strains have been isolated from diverse niches, including soil, water, and marine sediments and root nodules of diverse symbiotic plants...
  17. Bujnicki J, Rychlewski L. Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases. Acta Microbiol Pol. 2001;50:7-17 pubmed
    ..Comparison of a three-dimensional model of the Agr family member with a recently solved structure of reovirus mRNA capping MTase suggests that the mechanism of guanine-N7 methylation in rRNA and mRNA may be different...
  18. Gacto M, Vicente Soler J, Cansado J, Villa T. Characterization of an extracellular enzyme system produced by Micromonospora chalcea with lytic activity on yeast cells. J Appl Microbiol. 2000;88:961-7 pubmed
    Growth of Micromonospora chalcea on a defined medium containing laminarin as the sole carbon source induced the production of an extracellular enzyme system capable of lysing cells of various yeast species...
  19. Garcia L, Martínez Molina E, Trujillo M. Micromonospora pisi sp. nov., isolated from root nodules of Pisum sativum. Int J Syst Evol Microbiol. 2010;60:331-7 pubmed publisher
    ..The 16S rRNA gene sequence of strain GUI 15(T) showed highest similarity to Micromonospora pattaloongensis TJ2-2(T) (98.7 %) and Polymorphospora rubra TT 97-42(T) (98.5 %)...
  20. Gao Q, Thorson J. The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710. FEMS Microbiol Lett. 2008;282:105-14 pubmed publisher
    ..The development of a genetic system for the dynemicin producer Micromonospora chersina confirmed, for the first time, the requirement of the putative enediyne core biosynthetic genes (..
  21. Trujillo M, Kroppenstedt R, Fernández Molinero C, Schumann P, Martínez Molina E. Micromonospora lupini sp. nov. and Micromonospora saelicesensis sp. nov., isolated from root nodules of Lupinus angustifolius. Int J Syst Evol Microbiol. 2007;57:2799-804 pubmed
    ..chemotaxonomic and morphological analyses demonstrated that all six strains belonged to the genus Micromonospora. According to the 16S rRNA gene sequence data, the strains were divided into two clusters that are moderately ..
  22. Huang H, Wu X, Yi S, Zhou Z, Zhu J, Fang Z, et al. Rifamycin S and its geometric isomer produced by a newly found actinomycete, Micromonospora rifamycinica. Antonie Van Leeuwenhoek. 2009;95:143-8 pubmed publisher
    ..The morphological and genomic data showed that the strain merits description as a novel species, proposed as Micromonospora rifamycinica...
  23. Tsukada S, Anzai Y, Li S, Kinoshita K, Sherman D, Kato F. Gene targeting for O-methyltransferase genes, mycE and mycF, on the chromosome of Micromonospora griseorubida producing mycinamicin with a disruption cassette containing the bacteriophage phi C31 attB attachment site. FEMS Microbiol Lett. 2010;304:148-56 pubmed publisher
    Mycinamicin, a 16-membered macrolide antibiotic produced by Micromonospora griseorubida, comprises a macrolactone and two deoxysugars: desosamine and mycinose...
  24. Kojic M, Topisirovic L, Vasiljevic B. Cloning and characterization of an aminoglycoside resistance determinant from Micromonospora zionensis. J Bacteriol. 1992;174:7868-72 pubmed
    The sisomicin-gentamicin resistance methylase (sgm) gene was isolated from Micromonospora zionensis and cloned in Streptomyces lividans...
  25. Thawai C, Kittakoop P, Tanasupawat S, Suwanborirux K, Sriklung K, Thebtaranonth Y. Micromonosporin A, a novel 24-membered polyene lactam macrolide from Micromonospora sp. isolated from peat swamp forest. Chem Biodivers. 2004;1:640-5 pubmed
    ..1) was isolated from the actinomycete, Micromonospora sp. strain TT1-11, which was isolated from a very acidic peat swamp forest.
  26. Zhang L, Xi L, Ruan J, Huang Y. Micromonospora yangpuensis sp. nov., isolated from a sponge. Int J Syst Evol Microbiol. 2012;62:272-8 pubmed publisher
    ..011(T) indicated the highest similarity (98.7?%) to Micromonospora auratinigra JCM 12357(T), Micromonospora chaiyaphumensis JCM 12873(T) and Micromonospora echinofusca JCM 3327(..
  27. Trujillo M, Alonso Vega P, Rodriguez R, Carro L, Cerda E, Alonso P, et al. The genus Micromonospora is widespread in legume root nodules: the example of Lupinus angustifolius. ISME J. 2010;4:1265-81 pubmed publisher
    ..16S rRNA gene sequencing and phylogenetic analyses confirmed that all strains isolated belonged to the genus Micromonospora and that some of them may represent new species...
  28. Rodriguez E, Peirú S, Carney J, Gramajo H. In vivo characterization of the dTDP-D-desosamine pathway of the megalomicin gene cluster from Micromonospora megalomicea. Microbiology. 2006;152:667-73 pubmed
    In vivo reconstitution of the dTDP-D-desosamine pathway of the megalomicin gene cluster from Micromonospora megalomicea was achieved by expression of the genes in Escherichia coli...
  29. Huang H, Lv J, Hu Y, Fang Z, Zhang K, Bao S. Micromonospora rifamycinica sp. nov., a novel actinomycete from mangrove sediment. Int J Syst Evol Microbiol. 2008;58:17-20 pubmed publisher
    ..The strain showed closest 16S rRNA gene sequence similarity to Micromonospora matsumotoense (98.0%)...
  30. Igarashi Y, Ogura H, Furihata K, Oku N, Indananda C, Thamchaipenet A. Maklamicin, an antibacterial polyketide from an endophytic Micromonospora sp. J Nat Prod. 2011;74:670-4 pubmed publisher
    ..polyketide, maklamicin (1), was isolated from the culture extract of an endophytic actinomycete of the genus Micromonospora. The structure and relative configuration of 1 were elucidated by interpretation of NMR and other ..
  31. Zazopoulos E, Huang K, Staffa A, Liu W, Bachmann B, Nonaka K, et al. A genomics-guided approach for discovering and expressing cryptic metabolic pathways. Nat Biotechnol. 2003;21:187-90 pubmed
    ..This technology can be used to increase the scope and diversity of natural-product discovery...
  32. Ratnayake A, Janso J, Feng X, Schlingmann G, Goljer I, Carter G. Evaluating indole-related derivatives as precursors in the directed biosynthesis of diazepinomicin analogues. J Nat Prod. 2009;72:496-9 pubmed publisher
    ..halogenated anthranilates, and various substituted indoles into growing actinomycete culture DPJ15 (genus Micromonospora)...
  33. Hong W, Hong W, Ge M, Zeng Z, Zhu L, Luo M, et al. Molecular cloning and sequence analysis of the sisomicin biosynthetic gene cluster from Micromonospora inyoensis. Biotechnol Lett. 2009;31:449-55 pubmed publisher
    b>Micromonospora inyoensis produces sisomicin (Sm), an aminoglycoside antibiotic. The gene cluster of sisomicin biosynthesis spanning ca...
  34. Kasai H, Tamura T, Harayama S. Intrageneric relationships among Micromonospora species deduced from gyrB-based phylogeny and DNA relatedness. Int J Syst Evol Microbiol. 2000;50 Pt 1:127-34 pubmed
    The phylogenetic structure of genus Micromonospora within actinomycetes was examined by analysing the gyrB sequences of 15 validly described species and four subspecies...
  35. McAlpine J, Banskota A, Charan R, Schlingmann G, Zazopoulos E, Piraee M, et al. Biosynthesis of diazepinomicin/ECO-4601, a Micromonospora secondary metabolite with a novel ring system. J Nat Prod. 2008;71:1585-90 pubmed publisher
    ..These studies highlight the enzymatic complexity needed to produce this structural type, which is rare in nature...
  36. Unwin J, Standage S, Alexander D, Hosted T, Horan A, Wellington E. Gene cluster in Micromonospora echinospora ATCC15835 for the biosynthesis of the gentamicin C complex. J Antibiot (Tokyo). 2004;57:436-45 pubmed
    ..is a 4,6-disubstituted aminocyclitol antibiotic complex synthesised by some members of the actinomycete genus Micromonospora. In a search for the gentamicin biosynthetic gene cluster we identified, using a cosmid library approach, a ..
  37. Fang J, Zhang Y, Huang L, Jia X, Zhang Q, Zhang X, et al. Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics. J Bacteriol. 2008;190:6014-25 pubmed publisher
    Tetrocarcin A (TCA), produced by Micromonospora chalcea NRRL 11289, is a spirotetronate antibiotic with potent antitumor activity and versatile modes of action...
  38. Savic M, Ilic Tomic T, Macmaster R, Vasiljevic B, Conn G. Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm. J Bacteriol. 2008;190:5855-61 pubmed publisher
    The 16S rRNA methyltransferase Sgm from "Micromonospora zionensis" confers resistance to aminoglycoside antibiotics by specific modification of the 30S ribosomal A site...
  39. Hosted T, Wang T, Horan A. Characterization of the Micromonospora rosaria pMR2 plasmid and development of a high G+C codon optimized integrase for site-specific integration. Plasmid. 2005;54:249-58 pubmed publisher
    pMR2, an 11.1 kb plasmid was isolated from Micromonospora rosaria SCC2095, NRRL3718, and its complete nucleotide sequence determined...
  40. Peirú S, Rodriguez E, Tran C, Carney J, Gramajo H. Characterization of the heterodimeric MegBIIa:MegBIIb aldo-keto reductase involved in the biosynthesis of L-mycarose from Micromonospora megalomicea. Biochemistry. 2007;46:8100-9 pubmed
    ..12 of aldo-keto reductase (AKR12) superfamily of enzymes, were identified in the megalomicin gene cluster from Micromonospora megalomicea. Proteins from this family are involved in the metabolism of TDP-sugars by actinomycetes...
  41. Newstead S, Watson J, Knoll T, Bennet A, Taylor G. Structure and mechanism of action of an inverting mutant sialidase. Biochemistry. 2005;44:9117-22 pubmed
    Mutagenesis of the conserved tyrosine (Y370) of the Micromonospora viridifaciens sialidase to small amino acids changes the mechanism of catalysis from retention of anomeric configuration to inversion [Watson, J. N., et al...
  42. Sheoran A, King A, Velasco A, Pero J, Garneau Tsodikova S. Characterization of TioF, a tryptophan 2,3-dioxygenase involved in 3-hydroxyquinaldic acid formation during thiocoraline biosynthesis. Mol Biosyst. 2008;4:622-8 pubmed publisher
    ..We have expressed the Micromonospora sp. ML1 tryptophan 2,3-dioxygenase(TDO) TioF, purified it from E...
  43. Carro L, Veyisoglu A, Riesco R, Sproer C, Klenk H, Sahin N, et al. Micromonospora phytophila sp. nov. and Micromonospora luteiviridis sp. nov., isolated as natural inhabitants of plant nodules. Int J Syst Evol Microbiol. 2017;: pubmed publisher
    ..both presented chemotaxonomic and morphological properties consistent with their classification in the genus Micromonospora. For strains SG15T and SGB14T, the highest 16S rRNA gene sequence similarities were ..
  44. Belecki K, Crawford J, Townsend C. Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures. J Am Chem Soc. 2009;131:12564-6 pubmed publisher
  45. Watson J, Indurugalla D, Cheng L, Narine A, Bennet A. The hydrolase and transferase activity of an inverting mutant sialidase using non-natural beta-sialoside substrates. Biochemistry. 2006;45:13264-75 pubmed
    The Y370G inverting mutant sialidase from Micromonospora viridifaciens possesses beta-sialidase activity with phenyl beta-sialoside (Ph-betaNeuAc) to give alpha-sialic acid as the first formed product...
  46. McCoy J, Johnson H, Singh S, Bingman C, Lei I, Thorson J, et al. Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway. Proteins. 2009;74:50-60 pubmed publisher
  47. Chan J, Sandhu G, Bennet A. A mechanistic study of sialic acid mutarotation: implications for mutarotase enzymes. Org Biomol Chem. 2011;9:4818-22 pubmed publisher
    ..The mechanistic implications for Neu5Ac mutarotases are discussed. ..
  48. Trujillo M, Fernández Molinero C, Velázquez E, Kroppenstedt R, Schumann P, Mateos P, et al. Micromonospora mirobrigensis sp. nov. Int J Syst Evol Microbiol. 2005;55:877-80 pubmed
    ..The 16S rRNA gene sequence of strain WA201(T) showed closest similarity to the type strains of Micromonospora carbonacea (98.5 %) and Micromonospora matsumotoense (98.1 %)...
  49. de Menezes A, Lockhart R, Cox M, Allison H, McCarthy A. Cellulose degradation by micromonosporas recovered from freshwater lakes and classification of these actinomycetes by DNA gyrase B gene sequencing. Appl Environ Microbiol. 2008;74:7080-4 pubmed publisher
    A number of Micromonospora strains isolated from the water column, sediment, and cellulose baits placed in freshwater lakes were shown to be able to degrade cellulose in lake water without any addition of nutrients...
  50. Antal N, Fiedler H, Stackebrandt E, Beil W, Ströch K, Zeeck A. Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp. Tü 6368. I. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo). 2005;58:95-102 pubmed
    ..families, respectively, and the new lumichrome derivative 1-(alpha-ribofuranosyl)-lumichrome (4) from Micromonospora strain Tü 6368, isolated from a soil sample collected in Romania...
  51. Crimmins M, Vanier G. Enantioselective total synthesis of (+)-SCH 351448. Org Lett. 2006;8:2887-90 pubmed
    ..structure: see text] A stereoselective synthesis of SCH 351448 has been completed. Twelve of the fourteen stereogenic centers were established through chiral enolate reactions, and six key C-C bonds were formed by metathesis reactions. ..
  52. Biswas T, Zolova O, Lombo F, de la Calle F, Salas J, Tsodikov O, et al. A new scaffold of an old protein fold ensures binding to the bisintercalator thiocoraline. J Mol Biol. 2010;397:495-507 pubmed publisher
    ..Taken together, these observations rule out a direct enzymatic function of TioX and suggest that TioX is involved in thiocoraline resistance or secretion...
  53. Shidmoossavee F, Cheng L, Watson J, Bennet A. Brønsted analysis of an enzyme-catalyzed pseudo-deglycosylation reaction: mechanism of desialylation in sialidases. Biochemistry. 2010;49:6473-84 pubmed publisher
    The Micromonospora viridifaciens Y370G inverting mutant sialidase has been found to possess beta-sialidase activity with various fluoro-substituted phenyl beta-sialosides...
  54. Bruender N, Holden H. Probing the catalytic mechanism of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose. Protein Sci. 2012;21:876-86 pubmed publisher
    ..The biosynthesis of this highly unusual sugar in Micromonospora chalcea requires 10 enzymes...
  55. Iznaga Y, Lemus M, Gonzalez L, Garmendia L, Nadal L, Vallin C. Antifungal activity of actinomycetes from Cuban soils. Phytother Res. 2004;18:494-6 pubmed
    ..Our screening method indicated the presence of many possible polyene macrolide antibiotics and the important antifungal activity in the soils rich in minerals...
  56. Lombo F, Velasco A, Castro A, de la Calle F, Brana A, Sánchez Puelles J, et al. Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two streptomyces species. Chembiochem. 2006;7:366-76 pubmed
    Thiocoraline is a thiodepsipeptide antitumor compound produced by two actinomycetes Micromonospora sp. ACM2-092 and Micromonospora sp...
  57. Hirsch P, Mevs U, Kroppenstedt R, Schumann P, Stackebrandt E. Cryptoendolithic actinomycetes from antarctic sandstone rock samples: Micromonospora endolithica sp. nov. and two isolates related to Micromonospora coerulea Jensen 1932. Syst Appl Microbiol. 2004;27:166-74 pubmed
    ..5%) and clustering (98.5%) with Micromonospora coerulea DSM 43143T...
  58. Iizaka Y, Higashi N, Ishida M, Oiwa R, Ichikawa Y, Takeda M, et al. Function of cytochrome P450 enzymes RosC and RosD in the biosynthesis of rosamicin macrolide antibiotic produced by Micromonospora rosaria. Antimicrob Agents Chemother. 2013;57:1529-31 pubmed publisher
    ..P450 enzyme-encoding genes rosC and rosD were cloned from the rosamicin biosynthetic gene cluster of Micromonospora rosaria IFO13697...
  59. Kharel M, Subba B, Lee H, Liou K, Woo J, Sohng J. An approach for cloning biosynthetic genes of 2-deoxystreptamine-containing aminocyclitol antibiotics: isolation of a biosynthetic gene cluster of tobramycin from Streptomyces tenebrarius. Biotechnol Lett. 2003;25:2041-7 pubmed
    Genes homologous to 2-deoxystreptamine (DOS) biosynthetic genes were isolated from aminoglycoside producers, Micromonospora and Streptomyces spp...
  60. Kim B, Wengerter K, Benz R. The cell wall of Micromonospora purpurea contains a high conductance channel. Arch Microbiol. 2002;177:184-91 pubmed
    In this communication it is demonstrated that the cell wall of the gram-positive bacterium Micromonospora purpurea contains a cell wall channel for the passage of hydrophilic solutes...
  61. Huong N, Hoang N, Hong S, Sohng J, Yoon Y, Park J. Characterization of fortimicin aminoglycoside profiles produced from Micromonospora olivasterospora DSM 43868 by high-performance liquid chromatography-electrospray ionization-ion trap-mass spectrometry. Anal Bioanal Chem. 2016;408:1667-78 pubmed publisher
    ..of the biosynthetic congeners involved in the aminocyclitol aminoglycosidic fortimicin pathway from Micromonospora olivasterospora fermentation. The usage of both acid extraction (pH ∼2...
  62. Trujillo M, Kroppenstedt R, Schumann P, Carro L, Martínez Molina E. Micromonospora coriariae sp. nov., isolated from root nodules of Coriaria myrtifolia. Int J Syst Evol Microbiol. 2006;56:2381-5 pubmed
    ..The 16S rRNA gene sequence of strain NAR01(T) showed most similarity to the type strains of Micromonospora endolithica (98.94 %) and Micromonospora chersina (98.4 %)...
  63. Sakai A, Mitsumori A, Furukawa M, Kinoshita K, Anzai Y, Kato F. Production of a hybrid 16-membered macrolide antibiotic by genetic engineering of Micromonospora sp. TPMA0041. J Ind Microbiol Biotechnol. 2012;39:1693-701 pubmed publisher
    ..Mycinamicin II, a 16-member macrolide antibiotic produced by Micromonospora griseorubida A11725, contains a branched lactone and two different deoxyhexose sugars, D-desosamine and D-..
  64. Zhang C, Bitto E, Goff R, Singh S, Bingman C, Griffith B, et al. Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chem Biol. 2008;15:842-53 pubmed publisher
    ..This work also reveals the common GT-B structural fold can now be extended to include enediyne GTs...