Summary: A family of gram-positive, saprophytic bacteria occurring in soil and aquatic environments.

Top Publications

  1. Monciardini P, Cavaletti L, Ranghetti A, Schumann P, Rohde M, Bamonte R, et al. Novel members of the family Micromonosporaceae, Rugosimonospora acidiphila gen. nov., sp. nov. and Rugosimonospora africana sp. nov. Int J Syst Evol Microbiol. 2009;59:2752-8 pubmed publisher
    ..On the basis of 16S rRNA gene sequence analysis, the strains are members of the family Micromonosporaceae. The two strains contain hydroxydiaminopimelic acid, glycine, alanine and glutamic acid in the peptidoglycan...
  2. Tsueng G, Lam K. A preliminary investigation on the growth requirement for monovalent cations, divalent cations and medium ionic strength of marine actinomycete Salinispora. Appl Microbiol Biotechnol. 2010;86:1525-34 pubmed publisher
    ..29 to 15.2 mS/cm). S. arenicola has a lower growth requirement for ionic strength than S. tropica and S. pacifica...
  3. Choi B, Shin C. Isolation and characterization of a novel intracellular glucosyltransferase from the acarbose producer Actinoplanes sp. CKD485-16. Appl Microbiol Biotechnol. 2004;65:273-80 pubmed
    ..Various acarbose analogs were tested as inhibitors against the GTase as a means to suppress component C formation. Valienamine was the most potent, with an IC(50) value of 2.4x10(-3) mM and showed a competitive inhibition mode...
  4. Sosio M, Kloosterman H, Bianchi A, de Vreugd P, Dijkhuizen L, Donadio S. Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus. Microbiology. 2004;150:95-102 pubmed
    ..They both recognize N-acetylglucosamine as the substrate. tGtfA can add a sugar residue in the presence or absence of N-acetylglucosamine at amino acid 4, while tGtfB can only glycosylate the teicoplanin aglycon...
  5. Choi B, Shin C. Reduced formation of byproduct component C in acarbose fermentation by Actinoplanes sp. CKD485-16. Biotechnol Prog. 2003;19:1677-82 pubmed
    ..Effects were similar in a 1,500-L pilot fermentor with acarbose and component C yields of 3,490 and 43 mg/L at 500 mOsm/kg, respectively...
  6. Park H, Lee J, Hwang J, Park D, Kim C. Glycerol affects the acyl moieties of teicoplanin components produced by Actinoplanes teichomyceticus MSl2210. Microbiol Res. 2009;164:588-92 pubmed
    ..Analysis of the total cell lipids upon the addition of glycerol also showed a corresponding change in the proportion of teicoplanin, suggesting that glycerol strongly affects a change of teicoplanin branched acyl moieties...
  7. Jung H, Jeya M, Kim S, Moon H, Kumar Singh R, Zhang Y, et al. Biosynthesis, biotechnological production, and application of teicoplanin: current state and perspectives. Appl Microbiol Biotechnol. 2009;84:417-28 pubmed publisher
    ..This review summarizes the current state of the action mechanism, antibacterial activity, resistance mechanism, biotechnological production, and application of teicoplanin...
  8. Magarvey N, Keller J, Bernan V, Dworkin M, Sherman D. Isolation and characterization of novel marine-derived actinomycete taxa rich in bioactive metabolites. Appl Environ Microbiol. 2004;70:7520-9 pubmed
    ..for the two new genera (represented by strains of the PNG1 clade and strain UMM518) within the family Micromonosporaceae. Biological activity testing of fermentation products from the new marine-derived actinomycetes revealed ..
  9. Wang X, Jia F, Liu C, Zhao J, Wang L, Shen Y, et al. Xiangella phaseoli gen. nov., sp. nov., a member of the family Micromonosporaceae. Int J Syst Evol Microbiol. 2013;63:2138-45 pubmed publisher
    ..of the 16S rRNA gene sequence indicated that NEAU-J5(T) is phylogenetically related to members of the family Micromonosporaceae. The whole-cell sugars were galactose, mannose and glucose...

More Information


  1. Wehmeier U, Piepersberg W. Biotechnology and molecular biology of the alpha-glucosidase inhibitor acarbose. Appl Microbiol Biotechnol. 2004;63:613-25 pubmed
  2. Xie Q, Wang C, Wang R, Qu Z, Lin H, Goodfellow M, et al. Jishengella endophytica gen. nov., sp. nov., a new member of the family Micromonosporaceae. Int J Syst Evol Microbiol. 2011;61:1153-9 pubmed publisher
    ..analysis based on 16S rRNA gene sequences suggested that strain 202201(T) fell within the family Micromonosporaceae. The strain formed an extensively branched substrate mycelium, which carried uneven warty-surfaced spores...
  3. Tsueng G, Lam K. Growth of Salinispora tropica strains CNB440, CNB476, and NPS21184 in nonsaline, low-sodium media. Appl Microbiol Biotechnol. 2008;80:873-80 pubmed publisher
    ..tropica does not have a seawater growth requirement but requirement for a specific combination of salts to provide a balance of salts and maintain a high enough ionic strength for growth...
  4. Li K, Wie S, Huang L, Cheng X. An effective and simplified scale-up strategy for acarbose fermentation based on the carbon source control. World J Microbiol Biotechnol. 2012;28:749-53 pubmed publisher
    ..As a result, 4,327 mg of acarbose/l was obtained at 168 h of fermentation...
  5. Jensen P, Mafnas C. Biogeography of the marine actinomycete Salinispora. Environ Microbiol. 2006;8:1881-8 pubmed
  6. Li K, Zhou J, Wei S, Cheng X. An optimized industrial fermentation processes for acarbose production by Actinoplanes sp. A56. Bioresour Technol. 2012;118:580-3 pubmed publisher
    ..0-7.2 of pH value and 40-50% of DO concentration were favorable for acarbose production. As a result, the final acarbose yield was elevated to approximately 5000 mg/l at 168 h of fermentation...
  7. Williams P, Buchanan G, Feling R, Kauffman C, Jensen P, Fenical W. New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica. J Org Chem. 2005;70:6196-203 pubmed
    ..New SAR data for all eight compounds, derived from extensive testing against the human colon carcinoma HCT-116 and the 60-cell-line panel at the NCI, indicate that the chloroethyl moiety plays a major role in the enhanced activity of 1...
  8. Maldonado L, Fenical W, Jensen P, Kauffman C, Mincer T, Ward A, et al. Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae. Int J Syst Evol Microbiol. 2005;55:1759-66 pubmed
    ..of a group of marine actinomycetes previously designated MAR 1 and considered to belong to the family Micromonosporaceae. The organisms had phenotypic properties consistent with their assignment to this taxon...
  9. Tamura T, Hatano K, Suzuki K. A new genus of the family Micromonosporaceae, Polymorphospora gen. nov., with description of Polymorphospora rubra sp. nov. Int J Syst Evol Microbiol. 2006;56:1959-64 pubmed
    ..The isolates formed a distinct taxon in the phylogenetic tree of the Micromonosporaceae based on analysis of 16S rRNA gene sequences and showed chemical and phenotypic properties that were ..
  10. Wang Y, Liu L, Wang Y, Xue Y, Zheng Y, Shen Y. Actinoplanes utahensis ZJB-08196 fed-batch fermentation at elevated osmolality for enhancing acarbose production. Bioresour Technol. 2012;103:337-42 pubmed publisher
    ..0 g l(-1) maltose, 6.0 g l(-1) glucose and 9.0 g l(-1) soybean meal, at 48 h, 72 h, 96 h and 120 h. This intermittent fed-batch culture produced a peak acarbose titer of 4878 mg l(-1), increased by 15.9% over the batch culture...
  11. Tsueng G, Lam K. A low-sodium-salt formulation for the fermentation of salinosporamides by Salinispora tropica strain NPS21184. Appl Microbiol Biotechnol. 2008;78:821-6 pubmed publisher
    ..We demonstrated that while S. tropica strain NPS21184 is a novel marine actinomycete that requires high salt content for growth, it does not require sodium-chloride-based seawater-type media for growth and production of NPI-0052...
  12. Sun L, Li M, Wang Y, Zheng Y. Significantly enhanced production of acarbose in fed-batch fermentation with the addition of S-adenosylmethionine. J Microbiol Biotechnol. 2012;22:826-31 pubmed
    ..By way of this novel feeding strategy, the maximum titer of acarbose achieved was 6,113 mg/l at 192 h. To our knowledge, the production level of acarbose achieved in this study is the highest ever reported...
  13. Jensen P, Gontang E, Mafnas C, Mincer T, Fenical W. Culturable marine actinomycete diversity from tropical Pacific Ocean sediments. Environ Microbiol. 2005;7:1039-48 pubmed
    ..568 strains) belonged to the seawater-requiring marine taxon 'Salinospora', a new genus within the family Micromonosporaceae. A formal description of this taxon has been accepted for publication (Maldonado et al...
  14. Bucarey S, Penn K, Paul L, Fenical W, Jensen P. Genetic complementation of the obligate marine actinobacterium Salinispora tropica with the large mechanosensitive channel gene mscL rescues cells from osmotic downshock. Appl Environ Microbiol. 2012;78:4175-82 pubmed publisher
    ..The enhanced survival of the S. tropica transformant provides experimental evidence that the loss of mscL is associated with the failure of Salinispora spp. to grow in low-osmotic-strength media. ..
  15. Yang C, Huang Y, Chen C. Degradation of rutin by Thermoactinomyces vulgaris and other thermophilic compost isolates. J Agric Food Chem. 2009;57:5095-9 pubmed publisher
    ..vulgaris PU18-2 in the rutin-CYC medium. These results showed that the initial attack on rutin by the extracellular enzymes of T. vulgaris PU18-2 apparently was not through the glycosidase-mediated hydrolysis of glycosidic bond. ..
  16. Boakes S, Cortes J, Appleyard A, Rudd B, Dawson M. Organization of the genes encoding the biosynthesis of actagardine and engineering of a variant generation system. Mol Microbiol. 2009;72:1126-36 pubmed publisher
    ..Deletion of this gene resulted in the production of deoxy variants of actagardine, demonstrating that the formation of the sulfoxide group is enzyme catalysed and not a spontaneous chemical modification as previously believed. ..
  17. Piao C, Jin L, Zhao J, Liu C, Zhao Y, Wang X, et al. Longispora urticae sp. nov., isolated from rhizosphere soil of Urtica urens L., and emended descriptions of the species Longisporaalbida and Longisporafulva. Int J Syst Evol Microbiol. 2017;67:4228-4234 pubmed publisher
    ..nov. is proposed. The type strain is NEAU-PCY-3T (=DSM 105119T=CCTCC AA 2017017T)...
  18. Wang H, Chen Y, Ge L, Fang T, Meng J, Liu Z, et al. PCR screening reveals considerable unexploited biosynthetic potential of ansamycins and a mysterious family of AHBA-containing natural products in actinomycetes. J Appl Microbiol. 2013;115:77-85 pubmed publisher
    ..This work demonstrates that the AHBA-based screening method is a useful approach for discovering novel ansamycins and other AHBA-containing natural products from new microbial resources. ..
  19. Chen J, Su M, Shao L, Wang Y, Lin H, Chen D. Investigation of halogenation during the biosynthesis of ramoplanin in Actinoplanes sp. ATCC33076. Appl Microbiol Biotechnol. 2016;100:289-98 pubmed publisher
    ..This study has refined our understanding of how halogenation occurs in ramoplanin biosynthetic pathway, and lays the foundation for further exploitation of ramoplanin and enduracidin halogenase in combinatorial biosynthesis. ..
  20. Niehues B, Jossek R, Kramer U, Koch A, Jarling M, Schröder W, et al. Isolation and characterization of maltokinase (ATP:maltose 1-phosphotransferase) from Actinoplanes missouriensis. Arch Microbiol. 2003;180:233-9 pubmed
    ..Tryptic peptides of the enzyme were sequenced, and the sequences of these peptides will allow construction of degenerate primers to identify the gene coding for this unique kinase. ..
  21. Ohtaki A, Iguchi A, Mizuno M, Tonozuka T, Sakano Y, Kamitori S. Mutual conversion of substrate specificities of Thermoactinomyces vulgaris R-47 alpha-amylases TVAI and TVAII by site-directed mutagenesis. Carbohydr Res. 2003;338:1553-8 pubmed
  22. Ara I, Bakir M, Kudo T. Transfer of Catellatospora koreensis Lee et al. 2000 as Catelliglobosispora koreensis gen. nov., comb. nov. and Catellatospora tsunoense Asano et al. 1989 as Hamadaea tsunoensis gen. nov., comb. nov., and emended description of the genus Catellatospo. Int J Syst Evol Microbiol. 2008;58:1950-60 pubmed publisher
  23. Bhatnagar K, Singh V. Ca2+ -dependence and inhibition of transformation by trifluoperazine and chlorpromazine in Thermoactinomyces vulgaris. Curr Microbiol. 2003;46:265-9 pubmed
  24. Liao Z, Tang S, Guo L, Zhang Y, Tian X, Jiang C, et al. Verrucosispora lutea sp. nov., isolated from a mangrove sediment sample. Int J Syst Evol Microbiol. 2009;59:2269-73 pubmed publisher
    ..gifhornensis DSM 44337T was 38.2%. Based on its phenotypic and genotypic characteristics, strain YIM 013T (=CCTCC AA207012T=KCTC 19195T) is proposed to be the type strain of a novel species, Verrucosispora lutea sp. nov. ..
  25. Yamamura H, Hanawa K, Kusunoki M, Nakamura K, Nakagawa Y, Ishida Y, et al. Variation and predicted structure of the flagellin gene in Actinoplanes species. FEMS Microbiol Lett. 2011;324:21-7 pubmed publisher
    ..Phylogenetic analysis of the 115-amino acid N-terminal sequences revealed that the Actinoplanes species formed three clusters, and type II flagellin gene containing three type strains were phylogenetically closely related each other. ..
  26. Singh V. Mg2+ decreases arrhenius energies of activation for high temperature catalysis of phosphatases in Thermoactinomyces vulgaris. Curr Microbiol. 2007;55:179-84 pubmed
    ..The catalytic role of Mg(2+ )in enhancing the phosphatase activities was specified by the fact that this metal ion was able to recover the enzyme activities inhibited by dialysis and EDTA. ..
  27. Carro L, Nouioui I, Sangal V, Meier Kolthoff J, Trujillo M, Montero Calasanz M, et al. Genome-based classification of micromonosporae with a focus on their biotechnological and ecological potential. Sci Rep. 2018;8:525 pubmed publisher
    ..need to clarify relationships within the actinobacterial genus Micromonospora, the type genus of the family Micromonosporaceae, given its biotechnological and ecological importance...
  28. Ohtaki A, Mizuno M, Tonozuka T, Sakano Y, Kamitori S. Complex structures of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with acarbose and cyclodextrins demonstrate the multiple substrate recognition mechanism. J Biol Chem. 2004;279:31033-40 pubmed
    ..From the x-ray structures, it is suggested that the protonation of the O-4 atom is possibly carried out via a hydrogen atom of the inter-glucose hydrogen bond at the hydrolyzing site. ..
  29. Supong K, Suriyachadkun C, Suwanborirux K, Pittayakhajonwut P, Thawai C. Verrucosispora andamanensis sp. nov., isolated from a marine sponge. Int J Syst Evol Microbiol. 2013;63:3970-4 pubmed publisher
    ..Morphological and chemotaxonomic characteristics of the strain identified it as a member of the family Micromonosporaceae. Phylogenetic analysis based on 16S rRNA gene sequences showed similarity of the strain to Verrucosispora ..
  30. Xi L, Zhang L, Ruan J, Huang Y. Description of Verrucosispora qiuiae sp. nov., isolated from mangrove swamp sediment, and emended description of the genus Verrucosispora. Int J Syst Evol Microbiol. 2012;62:1564-9 pubmed publisher
    ..5826(T) =NBRC 106684(T)) is proposed as the type strain of a novel species, Verrucosispora qiuiae sp. nov. An emended description of the genus Verrucosispora is also provided. ..
  31. Jarling M, Bartkowiak K, Robenek H, Pape H, Meinhardt F. Isolation of phages infecting Actinoplanes SN223 and characterization of two of these viruses. Appl Microbiol Biotechnol. 2004;64:250-4 pubmed
    ..The latter phage is apparently widely distributed, as it was isolated from regions which are distantly located, i.e. more than 600 km apart from each other. ..
  32. Nolden S, Wagner N, Biener R, Schwartz D. Analysis of RegA, a pathway-specific regulator of the friulimicin biosynthesis in Actinoplanes friuliensis. J Biotechnol. 2009;140:99-106 pubmed publisher
    ..By real-time RT-PCR experiments, it was shown that the majority of the friulimicin biosynthetic genes is positively regulated by RegA. ..
  33. Shen Y, Liu C, Wang X, Zhao J, Jia F, Zhang Y, et al. Actinoplanes hulinensis sp. nov., a novel actinomycete isolated from soybean root (Glycine max (L.) Merr). Antonie Van Leeuwenhoek. 2013;103:293-8 pubmed publisher
    ..Therefore, it is proposed that strain NEAU-M9(T) represents a novel Actinoplanes species, Actinoplanes hulinensis sp. nov. The type strain of Actinoplanes hulinensis is NEAU-M9(T) (= CGMCC 4.7036(T) = DSM 45728(T)). ..
  34. Leemhuis H, Wehmeier U, Dijkhuizen L. Single amino acid mutations interchange the reaction specificities of cyclodextrin glycosyltransferase and the acarbose-modifying enzyme acarviosyl transferase. Biochemistry. 2004;43:13204-13 pubmed
    ..The opposite experiment, removing this typical His side chain in CGTase (H140A), introduced acarviosyl transferase activity in CGTase (0.25 micromol min(-1) mg(-1)). ..
  35. Thawai C, Tanasupawat S, Kudo T. Dactylosporangium tropicum sp. nov., isolated from soil. Int J Syst Evol Microbiol. 2011;61:2358-62 pubmed publisher
    ..On the basis of these phenotypic and genotypic data, the isolates represent a novel species, for which the name Dactylosporangium tropicum sp. nov. is proposed. The type strain is strain KB2-4(T) (?=?BCC 34760(T) ?=?JCM 15673(T)). ..
  36. Boakes S, Appleyard A, Cortes J, Dawson M. Organization of the biosynthetic genes encoding deoxyactagardine B (DAB), a new lantibiotic produced by Actinoplanes liguriae NCIMB41362. J Antibiot (Tokyo). 2010;63:351-8 pubmed publisher
    ..garbadinensis DeltagarA). Expression of this gene in A. garbadinensis DeltagarA resulted in the production of actagardine B, an oxidized form of DAB. ..
  37. Sazak A, Sahin N, Camas M. Actinoplanes abujensis sp. nov., isolated from Nigerian arid soil. Int J Syst Evol Microbiol. 2012;62:960-5 pubmed publisher
    ..Therefore, strain A4029T represents a novel species, for which the name Actinoplanes abujensis sp. nov. is proposed, with A4029T (=DSM 45518T=NRRL B-24835T=KCTC 19984T) as the type strain. ..
  38. Shiratori Takano H, Yamada K, Beppu T, Ueda K. Longispora fulva sp. nov., isolated from a forest soil, and emended description of the genus Longispora. Int J Syst Evol Microbiol. 2011;61:804-9 pubmed publisher
    ..of the isolate formed a monophyletic cluster with the single member of the genus Longispora in the family Micromonosporaceae. On the basis of morphological, chemotaxonomic and phylogenetic properties, strain KZ0017(T) represents a ..
  39. Ara I, Kudo T. Luedemannella gen. nov., a new member of the family Micromonosporaceae and description of Luedemannella helvata sp. nov. and Luedemannella flava sp. nov. J Gen Appl Microbiol. 2007;53:39-51 pubmed
    ..The chemotaxonomic data indicate that these strains belong to the family Micromonosporaceae. Phylogenetic analysis based on 16S rRNA gene sequence data suggested that the strains 3-9(24)(T), 3-21(27) ..
  40. Lohman D, Edwards D, Wolfenden R. Catalysis by desolvation: the catalytic prowess of SAM-dependent halide-alkylating enzymes. J Am Chem Soc. 2013;135:14473-5 pubmed publisher
    ..These rate enhancements, achieved without the assistance of cofactors, metal ions, or general acid-base catalysis, are the largest that have been reported for an enzyme that acts on two substrates. ..
  41. Pan H, Chen Z, Shao L, Li J, Chen J, Zhu C, et al. Production of ramoplanin analogues by genetic engineering of Actinoplanes sp. Biotechnol Lett. 2013;35:1685-92 pubmed publisher
    ..The MIC value of X1 was ~0.12 ?g/ml against Entrococcus sp. and was also active against vancomycin-resistant Staphylococcus aureus (MIC = 2 ?g/ml). ..
  42. Horbal L, Zaburannyy N, Ostash B, Shulga S, Fedorenko V. Manipulating the regulatory genes for teicoplanin production in Actinoplanes teichomyceticus. World J Microbiol Biotechnol. 2012;28:2095-100 pubmed publisher
    ..As an illustration of the utility of pSG5-based vector pKC1139, we improved teicoplanin production by the wild type strain via manipulations of two regulatory genes from the teicoplanin biosynthetic cluster, tcp28 and tcp29. ..
  43. Akparov V, Grishin A, Yusupova M, Ivanova N, Chestukhina G. Structural principles of the wide substrate specificity of Thermoactinomyces vulgaris carboxypeptidase T. Reconstruction of the carboxypeptidase B primary specificity pocket. Biochemistry (Mosc). 2007;72:416-23 pubmed
    ..Thus, notwithstanding the considerable structural similarity of CpT and pancreatic carboxypeptidases, the mechanisms underlying their substrate specificities are different. ..
  44. Kim B, Stach J, Weon H, Kwon S, Goodfellow M. Dactylosporangium luridum sp. nov., Dactylosporangium luteum sp. nov. and Dactylosporangium salmoneum sp. nov., nom. rev., isolated from soil. Int J Syst Evol Microbiol. 2010;60:1813-23 pubmed publisher
    ..nov. (type strain BK51T =DSM 45323T =KACC 20899T =NRRL B-24774T) and Dactylosporangium salmoneum sp. nov., nom. rev. (type strain NRRL B-16294T =ATCC 31222T =DSM 43910T =JCM 3272T =NBRC 14103T). ..
  45. Woods P, Robinson N, Swanson M, Reed C, Broadstone R, Derksen F. Airborne dust and aeroallergen concentration in a horse stable under two different management systems. Equine Vet J. 1993;25:208-13 pubmed
    ..When compared with System C, System R produced only 3% of the respirable dust burden in the breathing zone and a decreased aeroallergen challenge. ..
  46. Romeo L, Dalle Molle K, Zanoni G, Peretti A, Marangi G, Conrado L, et al. Respiratory health effects and immunological response to Thermoactinomyces among sugar cane workers in Nicaragua. Int J Occup Environ Health. 2009;15:249-54 pubmed
    ..Priority must be given to a surveillance and exposure prevention program for workers employed in sugar cane production and processing...
  47. Matsumoto N, Yamada M, Kurakata Y, Yoshida H, Kamitori S, Nishikawa A, et al. Crystal structures of open and closed forms of cyclo/maltodextrin-binding protein. FEBS J. 2009;276:3008-19 pubmed publisher
  48. Trachuk L, Letarov A, Kudelina I, Yusupova M, Chestukhina G. In vitro refolding of carboxypeptidase T precursor from Thermoactinomyces vulgaris obtained in Escherichia coli as cytoplasmic inclusion bodies. Protein Expr Purif. 2005;40:51-9 pubmed
  49. Brunkhorst C, Wehmeier U, Piepersberg W, Schneider E. The acbH gene of Actinoplanes sp. encodes a solute receptor with binding activities for acarbose and longer homologs. Res Microbiol. 2005;156:322-7 pubmed
    ..Together, these findings suggest that the AcbHFG complex might be involved in the uptake of acarbose and are consistent with a role for acarbose as a 'carbophor'...
  50. Nicolaou K, Harrison S. Total synthesis of abyssomicin C and atrop-abyssomicin C. Angew Chem Int Ed Engl. 2006;45:3256-60 pubmed
  51. Breyer S, Effenberger Neidnicht K, Knauer S, Schobert R. Synthesis, anticancer activity, and iron affinity of the Actinoplanes metabolite 7,8-dihydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione. Bioorg Med Chem. 2011;19:1264-7 pubmed publisher
  52. Ha H, Hwang Y, Choi S. Application of conjugation using phiC31 att/int system for Actinoplanes teichomyceticus, a producer of teicoplanin. Biotechnol Lett. 2008;30:1233-8 pubmed publisher
  53. Otsuka M, Akiyama T, Saikai T, Tanaka Y, Saizen H, Murakami S, et al. [A case of hypersensitity pneumonitis due to the contamination of a dehumidifier by Thermoactinomyces vulgaris]. Nihon Kokyuki Gakkai Zasshi. 2008;46:39-43 pubmed
    ..We diagnosed hypersensitity pneumonitis due to a dehumidifier contaminated by Thermoactinomyces vulgaris...
  54. Yokota T, Tonozuka T, Kamitori S, Sakano Y. The deletion of amino-terminal domain in Thermoactinomyces vulgaris R-47 alpha-amylases: effects of domain N on activity, specificity, stability and dimerization. Biosci Biotechnol Biochem. 2001;65:401-8 pubmed
    ..These results suggest domain N in TVAs is an important structure for stabilization of enzymes, recognition and hydrolysis of substrates, and dimerization of TVA II...
  55. Gousterova A, Braikova D, Goshev I, Christov P, Tishinov K, Vasileva Tonkova E, et al. Degradation of keratin and collagen containing wastes by newly isolated thermoactinomycetes or by alkaline hydrolysis. Lett Appl Microbiol. 2005;40:335-40 pubmed
    ..The aim of this study was to develop a method for microbial degradation of indigenous keratin wastes and to compare it with a method of alkaline hydrolysis...
  56. Kamitori S, Abe A, Ohtaki A, Kaji A, Tonozuka T, Sakano Y. Crystal structures and structural comparison of Thermoactinomyces vulgaris R-47 alpha-amylase 1 (TVAI) at 1.6 A resolution and alpha-amylase 2 (TVAII) at 2.3 A resolution. J Mol Biol. 2002;318:443-53 pubmed
    ..A structural comparison of the active sites has clearly revealed this difference in substrate specificity...
  57. Thawai C, Tanasupawat S, Itoh T, Kudo T. Actinocatenispora thailandica gen. nov., sp. nov., a new member of the family Micromonosporaceae. Int J Syst Evol Microbiol. 2006;56:1789-94 pubmed
    ..The chemotaxonomic characteristics of these strains coincided with those of the family Micromonosporaceae, i.e...
  58. Sosio M, Bianchi A, Bossi E, Donadio S. Teicoplanin biosynthesis genes in Actinoplanes teichomyceticus. Antonie Van Leeuwenhoek. 2000;78:379-84 pubmed
    ..teichomyceticus the genes for teicoplanin biosynthesis are closely linked to homologs of glycopeptide resistance commonly found in vancomycin-resistant enterococci...
  59. Smith S, Skerrett S, Chi E, Jonas M, Mohler K, Wilson C. The locus of tumor necrosis factor-alpha action in lung inflammation. Am J Respir Cell Mol Biol. 1998;19:881-91 pubmed
  60. Penn K, Jensen P. Comparative genomics reveals evidence of marine adaptation in Salinispora species. BMC Genomics. 2012;13:86 pubmed publisher
    ..The focus was on the obligate marine actinomycete genus Salinispora and the identification of marine adaptation genes that have been acquired from other marine bacteria...
  61. Wagner N, Osswald C, Biener R, Schwartz D. Comparative analysis of transcriptional activities of heterologous promoters in the rare actinomycete Actinoplanes friuliensis. J Biotechnol. 2009;142:200-4 pubmed publisher
    ..This confirmed the results of the promoter probe experiments that indicated quite weak promoter activity of P-ermE* in Actinoplanes...
  62. Goodfellow M, Brown R, Ahmed L, Pathom aree W, Bull A, Jones A, et al. Verrucosispora fiedleri sp. nov., an actinomycete isolated from a fjord sediment which synthesizes proximicins. Antonie Van Leeuwenhoek. 2013;103:493-502 pubmed publisher
    ..Isolate MG-37(T) (=NCIMB 14794(T) = NRRL-B-24892(T)) should therefore be classified as the type strain of a novel species of Verrucosispora for which the name Verrucosispora fiedleri is proposed...
  63. Shao L, Li J, Liu A, Chang Q, Lin H, Chen D. Efficient bioconversion of echinocandin B to its nucleus by overexpression of deacylase genes in different host strains. Appl Environ Microbiol. 2013;79:1126-33 pubmed publisher
    ..These results are useful for enhancing echinocandin B nucleus production in A. utahensis. Our study could enable the engineering of commercially useful echinocandin B nucleus-overproducing stains...
  64. Economou N, Zentner I, Lazo E, Jakoncic J, Stojanoff V, Weeks S, et al. Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach. Acta Crystallogr D Biol Crystallogr. 2013;69:520-33 pubmed publisher
    ..Insights derived from this new teicoplanin structure may contribute to the development of next-generation antibacterials designed to overcome bacterial resistance...
  65. Xie Q, Lin H, Li L, Brown R, Goodfellow M, Deng Z, et al. Verrucosispora wenchangensis sp. nov., isolated from mangrove soil. Antonie Van Leeuwenhoek. 2012;102:1-7 pubmed publisher
    ..nov. is proposed. The type strain is 234402(T) (=CCTCC AA 2011018(T)=DSM 45674(T))...
  66. Tseng M, Hoang K, Yang M, Yang S, Chu W. Polyester-degrading thermophilic actinomycetes isolated from different environment in Taiwan. Biodegradation. 2007;18:579-83 pubmed
    ..1%). Base on the morphological and chemical characteristics, these 31 isolates belonging to Actinomadura (12.9%), Microbispora (25.8%), Streptomyces (48.4%), Thermoactinomyces (9.7%) and Saccharomonospora genus (3.22%)...
  67. Wiese J, Jiang Y, Tang S, Thiel V, Schmaljohann R, Xu L, et al. A new member of the family Micromonosporaceae, Planosporangium flavigriseum gen. nov., sp. nov. Int J Syst Evol Microbiol. 2008;58:1324-31 pubmed publisher
    ..characterization and 16S rRNA gene sequence analysis indicated that the strain belonged to the family Micromonosporaceae. Strain YIM 46,034(T) showed more than 3 % 16S rRNA gene sequence divergence from recognized species of ..
  68. Lechner A, Eustáquio A, Gulder T, Hafner M, Moore B. Selective overproduction of the proteasome inhibitor salinosporamide A via precursor pathway regulation. Chem Biol. 2011;18:1527-36 pubmed publisher
    ..This study exemplifies the specialized regulation of a polyketide precursor pathway and its application to the selective overproduction of a specific natural product congener...
  69. Fiedler H, Bruntner C, Bull A, Ward A, Goodfellow M, Potterat O, et al. Marine actinomycetes as a source of novel secondary metabolites. Antonie Van Leeuwenhoek. 2005;87:37-42 pubmed
    ..New marine members of the rare genus Verrucosispora seem to be a promising source for novel bioactive secondary metabolites as shown in the case of the abyssomicin producing strain AB-18-032...
  70. Schwientek P, Szczepanowski R, Ruckert C, Stoye J, Pühler A. Sequencing of high G+C microbial genomes using the ultrafast pyrosequencing technology. J Biotechnol. 2011;155:68-77 pubmed publisher
  71. Licht A, Bulut H, Scheffel F, Daumke O, Wehmeier U, Saenger W, et al. Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for ?-D-galactopyranose. J Mol Biol. 2011;406:92-105 pubmed publisher
    ..The putative role of a galactose import system in the context of acarbose metabolism in Actinoplanes sp. is discussed...
  72. Matsumoto A, Takahashi Y, Shinose M, Seino A, Iwai Y, Omura S. Longispora albida gen. nov., sp. nov., a novel genus of the family Micromonosporaceae. Int J Syst Evol Microbiol. 2003;53:1553-9 pubmed
    ..nov., sp. nov., in the family MICROMONOSPORACEAE: The type strain is K97-0003(T) (=NRRL B-24201(T)=JCM 11711(T)).
  73. Tsueng G, Lam K. Stabilization effect of resin on the production of potent proteasome inhibitor NPI-0052 during submerged fermentation of Salinispora tropica. J Antibiot (Tokyo). 2007;60:469-72 pubmed
    ..Delay in resin addition to the fermentation led to decreases in the production of NPI-0052 to the amounts that are synthesized prior to the resin addition...
  74. Serina S, Radice F, Maffioli S, Donadio S, Sosio M. Glycopeptide resistance determinants from the teicoplanin producer Actinoplanes teichomyceticus. FEMS Microbiol Lett. 2004;240:69-74 pubmed
    ..However, similarly expressed MurF2 shows a small enzymatic activity only with D-Ala-D-lactate. Introduction of a single copy of the entire set of van genes confers resistance to teicoplanin-type glycopeptides to S. coelicolor...
  75. Husman K, Vohlonen I, Terho E, Mäntyjärvi R. Precipitins against microbes in mouldy hay in the sera of farmers with farmer's lung or chronic bronchitis and of healthy farmers. Eur J Respir Dis Suppl. 1987;152:122-7 pubmed
  76. Dai H, Wang J, Xin Y, Pei G, Tang S, Ren B, et al. Verrucosispora sediminis sp. nov., a cyclodipeptide-producing actinomycete from deep-sea sediment. Int J Syst Evol Microbiol. 2010;60:1807-12 pubmed publisher
    ..of the 16S rRNA gene of strain MS426T was determined and aligned with those of representatives of the family Micromonosporaceae available in public databases. Phylogenetic trees were inferred by using three algorithms...
  77. Lee D, Lee S. Allocatelliglobosispora scoriae gen. nov., sp. nov., isolated from volcanic ash. Int J Syst Evol Microbiol. 2011;61:264-70 pubmed publisher
    ..analysis based on 16S rRNA gene sequences showed that strain Sco-B14(T) formed a lineage within the family Micromonosporaceae and was distinct from established genera...
  78. Yamamura H, Miyazaki S, Ikoma K, Nakagawa Y, Hamada M, Otoguro M, et al. Virgisporangium myanmarense sp. nov., a novel motile actinomycete isolated from an anthill soil in Myanmar. J Antibiot (Tokyo). 2017;70:995-999 pubmed publisher
    ..nov. The type strain is MM04-1133T (=NBRC 112733T=VTCC 910008T)...
  79. Cao Y, Wang Q, Jin R, Jiang Y, Lai H, He W, et al. Planosporangium mesophilum sp. nov., isolated from rhizosphere soil of Bletilla striata. Int J Syst Evol Microbiol. 2011;61:1330-3 pubmed publisher
    ..nov. is proposed. The type strain is YIM 48875(T) (?=?CCTCC AA 209049(T) ?=?KCTC 19779(T))...
  80. Muranova T, Ruzheinikov S, Sedelnikova S, Baker P, Pasquo A, Galkin A, et al. Crystallization and preliminary X-ray analysis of substrate complexes of leucine dehydrogenase from Thermoactinomyces intermedius. Acta Crystallogr D Biol Crystallogr. 2002;58:1059-62 pubmed
    ..0 A(3) Da(-1). These crystals diffract X-rays on a synchrotron-radiation source to at least 2.8 and 3.3 A resolution, respectively, and are suitable for a full structure determination...
  81. Khan Z, Gangwar M, Gaur S, Randhawa H. Thermophilic actinomycetes in cane sugar mills: an aeromicrobiologic and seroepidemiologic study. Antonie Van Leeuwenhoek. 1995;67:339-44 pubmed
    ..The results indicate that clinically important thermophilic actinomycetes are widely prevalent in cane sugar mills, and T. sacchari and S. rectivirgula are the major species involved in the sensitization of the bagasse workers in India...
  82. Jensen P, Williams P, Oh D, Zeigler L, Fenical W. Species-specific secondary metabolite production in marine actinomycetes of the genus Salinispora. Appl Environ Microbiol. 2007;73:1146-52 pubmed
  83. Roberts A, Schultz A, Kersten R, Dorrestein P, Moore B. Iron acquisition in the marine actinomycete genus Salinispora is controlled by the desferrioxamine family of siderophores. FEMS Microbiol Lett. 2012;335:95-103 pubmed publisher
    ..Consequently, this study indicates that DFOs are the primary siderophores in laboratory cultures of Salinispora...
  84. Vidgen M, Hooper J, Fuerst J. Diversity and distribution of the bioactive actinobacterial genus Salinispora from sponges along the Great Barrier Reef. Antonie Van Leeuwenhoek. 2012;101:603-18 pubmed publisher
    ..pacifica" within the geographical area of the GBR alone. One of these new phylotypes possessed a localised regional distribution within the GBR...
  85. Hoertz A, Hamburger J, Gooden D, Bednar M, McCafferty D. Studies on the biosynthesis of the lipodepsipeptide antibiotic Ramoplanin A2. Bioorg Med Chem. 2012;20:859-65 pubmed publisher